| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 435297200 | Including perfusion means | 17 |
| 20090311777 | BIOREACTOR - The present invention relates to a bioreactor comprising a first fluid distribution chamber and a first fluid collection chamber, the reactor adapted to receive at least one conduit in fluid communication between the first fluid distribution chamber and the first fluid collection chamber; wherein the reactor includes a second fluid distribution means including a plurality of distributors arranged to distribute the second fluid between the first fluid distribution chamber and the first fluid collection chamber. The invention extends to a removable insert for a bioreactor comprising a first fluid distribution plate; a first fluid collection plate; and a second fluid distribution means including a plurality of distributors arranged to distribute the second fluid between the first fluid distribution plate and the first fluid collection plate. | 12-17-2009 |
| 20110256619 | MICROFABRICATED COMPOSITIONS AND PROCESSES FOR ENGINEERING TISSUES CONTAINING MULTIPLE CELL TYPES - The present invention relates to a three-dimensional system, and compositions obtained therefrom, wherein individual layers of the system comprise channels divided longitudinally into two compartments by a centrally positioned membrane, and wherein each compartment can comprise a different cell type. | 10-20-2011 |
| 20120322142 | BIOREACTOR - The present invention relates to a bioreactor comprising a first fluid distribution chamber and a first fluid collection chamber, the reactor adapted to receive at least one conduit in fluid communication between the first fluid distribution chamber and the first fluid collection chamber; wherein the reactor includes a second fluid distribution means including a plurality of distributors arranged to distribute the second fluid between the first fluid distribution chamber and the first fluid collection chamber. The invention extends to a removable insert for a bioreactor comprising a first fluid distribution plate; a first fluid collection plate; and a second fluid distribution means including a plurality of distributors arranged to distribute the second fluid between the first fluid distribution plate and the first fluid collection plate. | 12-20-2012 |
| 20130157353 | CELL-CULTURE-BAG - A cell-culture-bag for use in the expansion of stem cells from a crude biopsy, comprising: outer walls; a chamber located within the walls; a first inlet, and first and second outlets, providing fluid communication with the chamber, for connection to a perfusion apparatus; and a filter arrangement constructed to allow passage of red blood cells and block passage of stem cells from the first outlet, and block passage of microcarriers from the second outlet. | 06-20-2013 |
| 20140038279 | CELL CULTURE SYSTEM - The embodiments of the invention described herein relate to systems and methods for culturing and/or maintaining intestinal cells, tissues and/or organoids in vitro. The cells, tissues and/or organoids cultured according to the methods and systems described herein can mimic or reproduce natural intestinal epithelial structures and behavior as well as support co-culture of intestinal microflora. | 02-06-2014 |
| 20140045256 | CELL CHIP - There is provided a cell chip including: a first substrate having biomaterials fixed thereto; a second substrate provided with one or more receiving space in which a culture medium is stored; and a circulation unit circulating the culture medium stored in the receiving space. | 02-13-2014 |
| 20140120610 | SENSOR UNIT AND CONSTANT-TEMPERATURE DEVICE - In order to enable the inside of a constant-temperature device to be sterilized using sterilization gas and prevent contamination during incubation, even when provided with an atmosphere measuring means having a CO | 05-01-2014 |
| 20140154795 | BIOREACTOR USING ACOUSTIC STANDING WAVES - A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor. | 06-05-2014 |
| 20140170744 | CELL CULTURE DEVICE - There is provided a cell culture device including a cell chip accommodation unit accommodating a cell chip therein, a drug storage unit storing a drug and having a closed structure, a first pipe connecting the drug storage unit and the cell chip accommodation unit and transferring the drug from the drug storage unit to the cell chip accommodation unit, a second pipe connecting the drug storage unit and the cell chip accommodation unit and transferring the drug from the cell chip accommodation unit to the drug storage unit, and a pump circulating the drug between the cell chip accommodation unit and the drug storage unit. | 06-19-2014 |
| 20140234955 | CELL CULTURE DEVICE - There is provided a cell culture device including a cell chip receiving part coupled to a cell chip and having at least one passage through which a liquid-type medium is circulated, and a vortex generation part formed in the passage to generate a vortex in the liquid-type medium. | 08-21-2014 |
| 20140273199 | System And Method For Producing A Consistent Quality Syngas From Diverse Waste Materials With Heat Recovery Based Power Generation, And Renewable Hydrogen Co-Production - A system and method for converting waste and secondary materials into synthesis gas (syngas) through the use of a molten metal bath gasifier for the initial breakdown of waste feeds and an A/C plasma reactor for complete dissociation of waste feeds into syngas, and an anaerobic digester. The system includes a heat recovery and steam power generation process for the production of electricity. The system produces a net output of electricity above plant load sufficient for the co-production of renewable Hydrogen and Oxygen. The process does not require the use of fossil fuels or fossil feedstocks during normal operations, and it eliminates combustion produced stack emissions or landfill residuals. | 09-18-2014 |
| 435297300 | Including a spinning semipermeable membrane or filter | 2 |
| 20130260450 | BIOREACTOR WITH LID FOR EASY ACCESS TO INCUBATION CAVITY - There is provided a bioreactor which is provided with a lid ( | 10-03-2013 |
| 20150017714 | CENTRIFUGATION CHAMBER WITH GAS PERMEABLE MEMBRANE LAYERS FOR CELL CULTIVATION - The invention is directed to a centrifuge chamber comprising a cylinder having a base plate and a cover plate, a rotational axis with at least one port for input and/or output of liquids, at least one port for input of gases and at least one layer for cell culturing, wherein the layer for cell culturing comprises a gas-permeable membrane on which cells can be cultured and wherein the at least one port for input and/or output of gases is connected to the gas-permeable membrane. | 01-15-2015 |
| 435297400 | Including hollow fiber or capillary | 4 |
| 20090155895 | LIQUID-GAS-PHASE EXPOSURE REACTOR FOR CELL CULTURING - Initiation of growth and cultivation of cells can be performed by introducing the cells into culture compartments of a liquid-gas-phase exposure bioreactor containing a supply chamber in which there are disposed hollow-filament membranes having an inside diameter of no larger than 5 mm, wherein an inner volume of said hollow-filament membranes forms the culture compartments. Approximately one half of the supply chamber is filled with a nutrient medium and a remainder is filled with a gas mixture. Perfusion of medium and gas is turned on simultaneously or separately. The hollow-filament membranes and the cells contained therein are cyclically exposed to the gas or liquid phase. | 06-18-2009 |
| 20130059371 | Device, System and Process for Modification or Concentration of Cell-depleted Fluid - A product concentration device that utilizes a reservoir connected to a hollow-fiber filter element where the reservoir can serve as a container for filtrate emanating from another filtering device, such that product in the reservoir can be stored, concentrated and/or further processed as desired. Enclosed reactor systems, each of at least three chambers, fluid flow between the chambers controlled by selectively permeable barriers, flow controlled by an alternating flow diaphragm pump. | 03-07-2013 |
| 20130295662 | Apparatus and Method for Growing Cells - A system and method for culturing cells is provided that includes an extra-capillary space between at least one permeable hollow fiber and an enclosed chamber. Cells are placed in the extra-capillary space to grow. One or more reservoirs containing cell-culture media and/or an oxygen-containing gas are provided in communication with the at least one fiber. The system is configured to generate alternating flows of both the cell-culture media and the gas through a lumen of the hollow fiber(s), thereby passing both nutrients and gas through the walls of the fiber(s) to the cells in the extra-capillary space to provide a suitable environment for growth and/or proliferation of the cells. Flows of liquid and gas through the hollow fiber(s) can be produced by gravity and/or various pumping configurations. | 11-07-2013 |
| 20140093952 | Bioreactor Tangential Flow Perfusion Filter System - A bioreactor hollow fiber perfusion system increases the capacity of standard fed batch bioreactors. The bioreactor hollow fiber perfusion system cycles bioreactor mass through a hollow fiber tangential flow filter which separates the metabolic wastes (as well as proteins) from the biomass material allowing the reactions in the bioreactor to continue when compared to a fed batch bioreactor. The bioreactor hollow fiber perfusion system preferably includes a low shear gamma stable disposable pumphead responsible for biomass re-cycling and can be easy installed or replaced without the risk of contamination. | 04-03-2014 |
