Entries |
Document | Title | Date |
20080299649 | Cell culture apparatus for co-culture of cells - A multilayered cell culture apparatus for the co-culturing of at least two cell types is disclosed. The cell co-culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between some cell culture chambers and the external environment. In addition, some cell culture chambers may have limited access to air creating relatively lower oxygen content cell culture chambers. The size of the apparatus, and location of an optional neck section, allows for its manipulation by standard automated assay equipment, further making the apparatus amenable to high throughput applications. | 12-04-2008 |
20080305540 | MEMBRANE SUPPORTED BIOREACTOR FOR CONVERSION OF SYNGAS COMPONENTS TO LIQUID PRODUCTS - Ethanol and other liquid products are produced by contacting syngas components such as CO or a mixture of CO | 12-11-2008 |
20090137032 | Cell- and Tissue Culture Device - The present invention relates to the field of cell and tissue culture. In particular, the invention provides a novel device for organotypic culture. The device comprises a medium conduit having one open end and one end closed by a porous membrane fused across it; and a frame holding the medium conduit in a substantially vertical orientation; wherein the medium conduit is adapted to permit retention by capillarity of a sufficient volume of liquid culture medium in the medium conduit to contact the surface of the porous membrane and thus supply nutrients to cells that may be grown on the porous membrane. The device may further comprise a cell suspension conduit having one end open and one end closed by the surface of said porous membrane contralateral to the surface of said porous membrane sealed to said medium conduit; wherein said frame holds the medium conduit and the cell suspension conduit in a substantially vertical orientation. | 05-28-2009 |
20090176301 | DISPOSABLE SPINNER FLASK - A disposable spinner flask includes an asymmetric container, a lid, and a spinning mechanism. The container can be sealingly coupled to the lid, which includes an access port and a cap configured to be coupled to the access port for preventing bacteria, viruses, and fungi from passing therethrough while allowing air to flow between the container and a surrounding environment. The lid may include a structure for retaining the cap when the cap is removed. The spinning mechanism can include a shaft, at least one blade, and a magnetic device. Further, the spinning mechanism can include a receptacle that fixedly receives the magnetic device toward an end of the blade assembly, the magnetic device configured to rotate when subjected to an external magnetic force. | 07-09-2009 |
20090197327 | Culturing Bag - A culturing bag for microorganisms has a wall formed of plastic film wherein at least one wall area of the wall is permeable for oxygen and carbon dioxide. A first layer of microporous film is attached to the at least one wall area as an exterior layer so as to form a multi-layer configuration in the at least one wall area. The first layer of microporous film is sealed by a seal-tight edge seam to the wall. The microporous film is adapted to be torn open or torn off. At least one second layer of microporous film can be placed between the exterior layer and the wall. | 08-06-2009 |
20090215163 | SYNGAS CONVERSION SYSTEM USING ASYMMETRIC MEMBRANE AND ANAEROBIC MICROORGANISM - A stable system for producing liquid products such as ethanol, butanol and other chemicals from syngas components contacts CO or a mixture of CO | 08-27-2009 |
20090263893 | Flexible membrane valve for cell culture vessel - An assembly for culturing cells includes a housing defining a reservoir for containing cell culture media and an opening in fluid communication with the reservoir. The cell culture assembly further includes a filter valve assembly configured to sealingly engage the opening. The filter valve assembly includes a flexible membrane, a contiguous side wall, an end wall, and a microbial filter. The end wall has an opening and extends across one end of the side wall to form a major cavity within the side wall and the end wall. The flexible membrane has a slit spanning the membrane and is disposable within the major cavity such that the membrane sealingly divides the major cavity into (i) a chamber formed between the end wall and the membrane and (ii) a minor cavity formed by the membrane and a portion of the side wall. The minor cavity is in fluid communication with the reservoir. The slit is biased in a closed position to prevent fluid from passing from the minor cavity into the chamber and is configured to open to allow gas to pass from the minor cavity into the chamber when the pressure differential across the membrane is above a threshold. The filter is disposed between the membrane and the opening such that air flowing through the opening in the end wall into the chamber passes through the filter. | 10-22-2009 |
20090298165 | Process for removing selenium from air or water - A process for removing selenium from air or water can use proteins naturally found in bacteria able to live in selenium rich environments to capture and/or reduce the selenium to an insoluble form that can be captured. | 12-03-2009 |
20100055776 | BIOREACTOR, ARRANGEMENT OF BIOREACTORS, PROCESS FOR PRODUCTION THEREOF AND USE THEREOF - The invention relates to a bioreactor including a housing having a lower housing half and an upper housing half that are respectively connected to one another on one side by a film joint. At least one of the upper or lower housing halves includes a device to exchange fluids. The bioreactor further includes at least one support element to support at least one cell culture substrate. The invention furthermore relates to an arrangement of such bioreactors, processes for production thereof and use thereof for culturing cells or as an implant. | 03-04-2010 |
20100120136 | BIOREACTOR FOR CELL AND TISSUE CULTURE - The present invention provides a bioreacto 1r for incubation of cell cultures, tissue biopsies, cell clusters, tissue-like structures, ‘prototissues’ or similar samples. The bioreactor is generally adapted for rotation for use in microgravity conditions and equipped with an incubation cavity having a small internal fluid volume, generally less than 1 ml. To avoid problems associated with small volume incubation, the bioreactor may include a humidity chamber or other means of avoiding dehydration as well as substantially fluid-tight closures for access ports that avoid introduction of air bubbles to the incubation cavity. The small-volume bioreactor permits long term maintenance of tissue differentiation states in cultures. Also provided are methods of incubating cells or tissues using the bioreactor including methods of creating molecular profiles of biological effects of chemical compositions on differentiated cell or tissue samples maintained in long term culture. | 05-13-2010 |
20100120137 | Apparatus for growing biological mass - An apparatus for growing biological mass has a container for accommodating and growing a biological mass, a unit for supplying liquid in the container, a unit for supplying CO | 05-13-2010 |
20100159580 | CELL CULTURE COMPARTMENT UNIT AND ARRAY INCLUDING THE SAME - Provided are a cell culture compartment unit and an array including the same. The cell culture compartment unit includes: a cell culture region and a bio material emission region including a cell culture fluid, which are separated with a porous membrane therebetween; a piezoelectric device on the porous membrane of the cell culture region; a thin layer for cell attachment being on the piezoelectric device and having at least one surface on which cells are attachable; and a first power supply applying a first electric field to the piezoelectric device. | 06-24-2010 |
20100159581 | Adsorbent Filter Media For Removal Of Biological Contaminants In Process Liquids - Adsorbent filter media particularly suited for removal of biological contaminants in process liquids. A porous fixed bed of adsorbent material is formed, using only a granular adsorbent and a water-insoluble thermoplastic binder. The resulting composite filter allows for a higher amount of adsorbent with smaller adsorbent particles than conventional depth filters. Elimination of cellulose fiber, as well as the elimination of the thermoset binder, results in reduced contamination of the process liquid. | 06-24-2010 |
20100227390 | Ethanol Water Solution Concentrating Device - A device for concentrating ethanol from an ethanol water solution yielded from lignocellulose is equipped with a water separation membrane, an ethanol water solution storing unit and a depressurizing container provided so as to sandwich the water separation membrane, a dry gas cylinder for supplying dry gas to an ethanol vapor residing unit above the ethanol water solution storing unit, a pump for sucking in the interior of the ethanol vapor residing unit, and a cold trap for collecting the concentrated ethanol by condensing the ethanol vapor sucked in by the pump. | 09-09-2010 |
20100273253 | DYNAMIC SYSTEMS FOR CULTURING CELLS IN 3D SUPPORTS - The present invention refers to the conception process of new dynamic systems for cell culture in | 10-28-2010 |
20110020922 | BIOREACTOR - The invention relates to a bioreactor for cultivating cells having a filter bag for separating culture fluid and cells, the filter medium of the filter bag having a degree of swelling of less than 1%. The bioreactor according to the invention is characterized by a high durability of the filter bag thereof. | 01-27-2011 |
20110076758 | APPARATUS FOR HIGH-THROUGHPUT CELL CULTURE WITH MECHANICAL COMPRESSION STIMULATION - An apparatus for high-throughput cell culture with mechanical compression stimulation includes a cell culture vessel and a fluid pressure supply unit. The cell culture vessel includes at least one culture chamber, at least one pressure chamber disposed above the culture chamber, a membrane disposed between the culture chamber and the pressure chamber, and at least one pressurizing member that projects downwardly from the membrane into the culture chamber. The fluid pressure supply unit is connected fluidly to the pressure chamber, and has a fluid pressure supply device to supply a pressurized fluid to the pressure chamber so as to deform the membrane and move the pressurizing member, and a control device that is adapted to vary a pressure of the pressurized fluid in the pressure chamber. | 03-31-2011 |
20110076759 | BIOREACTOR WITH CONDENSER - Bioreactor with a vessel having at least one gas dissipation duct for gas discharge, the orifice of the gas dissipation duct being connected to a hydrophobic sterile filter and to a condenser arranged between them and having condensation surfaces, a turbulence generator for generating a turbulent flow is arranged in the gas dissipation duct in the region of the condenser. | 03-31-2011 |
20110129913 | Device for cell culture - The device for cell culture comprises: a container body ( | 06-02-2011 |
20110165667 | Method and System for Converting Electricity Into Alternative Energy Resources - A system to convert electric power into methane includes a reactor having a first chamber and a second chamber separated by a proton permeable barrier. The first chamber includes a passage between an inlet and an outlet containing at least a porous electrically conductive cathode, a culture comprising living methanogenic microorganisms, and water. The second chamber includes at least an anode. The reactor has an operating state wherein the culture is maintained at a temperature above 50° C. The system also includes a source of electricity coupled to the anode and the cathode, and a supply of carbon dioxide coupled to the first chamber. The outlet of the system receives methane from the first chamber. | 07-07-2011 |
20110171724 | Apparatus and Method for Removing Microbial Contaminants From a Flowing Fluid - Methods and apparatuses for removing microbial contaminants from a flowing fluid in a cell culture incubator are disclosed. Some embodiments of the invention provide a cell culture incubator including a chamber, an airflow passage through which gasses circulate within the chamber, a filter configured to filter gasses that flow through the airflow passage and chamber, and a blower for circulating gasses through the airflow passage, chamber and filter. The blower includes a structural component at least partially formed from an anti-microbial material. | 07-14-2011 |
20110177587 | NUCLEIC ACID AMPLIFICATION WITH CONTINUOUS FLOW EMULSION - Embodiments of the present invention are directed to methods and devices/systems for amplifying genetic material and may include providing a water-in-oil emulsion in a continuous flow. The emulsion may include a plurality of water droplets comprising microreactors. Each of the plurality of microreactors may include a single bead capable of capturing a nucleic acid template, a single species nucleic acid template and sufficient reagents to amplify the copy number of the nucleic acid template. The method also includes flowing the emulsion across a first temperature zone and a second lower temperature zone to thermally process the microreactors to amplify the nucleic acid template by polymerase chain reaction. | 07-21-2011 |
20110183410 | BIOMASS POWER PLANT - The invention relates to a biomass power plant for dry-wet simultaneous fermentation, having dry fermenter modules comprising dry fermenters. In order to refine the biomass power plant such that the length of the pipes for delivering process water is reduced to a minimum, the invention proposes to integrate a process water reservoir between two dry fermenter modules. | 07-28-2011 |
20110207209 | CULTURE SYSTEMS, APPARATUS, AND RELATED METHODS AND ARTICLES - Culture systems, devices and related methods and articles may automate the culturing or incubation process according to defined culturing protocols. Such may employ removable multi-well growth cassette. Wells may be subdivided into subwells. Such may employ removable media and waste cartridges and/or gas canisters to supply consumables, which may be supplied in kits, for example with processor executable culturing protocols. Direct fluidic coupling between growth cassettes and the removable cartridges or canisters may be employed. Operational and/or environmental conditions may be sensed or monitored, and may be used to adjust or alter operation. A microscopy subsystem may capture images which may be stored and/or analyzed. Analysis may be used to adjust or alter operation. | 08-25-2011 |
20110263009 | METHOD FOR THE FILTRATION OF A BIOREACTOR LIQUID FROM A BIOREACTOR; CROSS-FLOW MEMBRANE MODULE, AND BIOREACTOR MEMBRANE SYSTEM - The invention provides a method for the filtration of a bioreactor liquid ( | 10-27-2011 |
20120058551 | TECHNOLOGY AND METHOD TO STUDY MICROBIAL GROWTH AND ADHESION TO HOST-RELATED SURFACES AND THE HOST-MICROBIOTA INTERACTIONS - The present invention relates to in vitro adhesion modules that allow growth, stabilization and study of microbial communities that adhere to and colonize host-related surfaces, that mimic transport of chemical compounds across epithelial surfaces and simulate host-microorganism interactions and adaptation. It includes the provision of micromolar amounts of oxygen via the basal side of a mucus layer towards the adhered microorganisms thus establishing the microaerophilic conditions prevailing at the base of a biofilm. It can also include cells, simulating the host, in a chamber on the basal side of a functional layer comprising said mucus layer. The adhesion module of the present invention can be placed between the different compartments of the SHIME—the Simulator of the Human Intestinal Microbial Ecosystem. An extension of the SHIME is made where the duodenum, jejunum and ileum are separately mimicked. | 03-08-2012 |
20120094372 | Ex Vivo Cell Culture: Enabling Process and Devices - A device which is capable of providing an artificial condition for three dimensional culture of animal and human cells comprising of two components; First component is a vessel coated in the entire internal surface rendered not suitable for cell adhesion and proliferation and a second component is a cell interactive biomaterial on which cells can attach and grow as monolayer or multiple layers in three dimensions. | 04-19-2012 |
20120238011 | CONTINUOUS RECOVERY HARVEST BAG - Disclosed herein is a single use continuous recovery, flow-through harvest vessel and corresponding method for harvesting culture medium and simultaneously either leaving the microcarrier beads behind in the vessel or flowing microcarrier beads and medium back into a bioreactor. | 09-20-2012 |
20120315693 | MULTILAYERED CELL CULTURE APPARATUS - A multilayered cell culture apparatus for the culturing of cells is disclosed. The cell culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between the cell culture chambers and the external environment. The flask body also includes an aperture that will allow access to the cell growth chambers by means of a needle or cannula. The size of the apparatus, and location of an optional neck and cap section, allows for its manipulation by standard automated assay equipment, further making the apparatus ideal for high throughput applications. | 12-13-2012 |
20130005027 | FILTRATION DEVICE AND SYSTEM - The invention relates to a filtration device ( | 01-03-2013 |
20130045532 | METHODS AND KITS FOR ISOLATING MICROORGANISMS FROM CULTURE - The present invention is directed to methods and kits for separating, accumulating, characterizing and/or identifying microorganisms known to be present or that may be present in a test sample. The method of the invention comprises optional lysing non-microorganism cells and/or particulates that may be present in a test sample, followed by a subsequent filtration step for isolation and/or accumulation of microorganisms. The kit of the present invention may comprise at least one filter membrane or an integrated filtration and sample transfer device for isolation and/or accumulation of microorganisms. | 02-21-2013 |
20130109086 | DISPOSABLE SET FOR CELL CULTURE, CELL CULTURE DEVICE AND CELL PREPARATION METHOD | 05-02-2013 |
20130115690 | Cell Culture Vessel and Cell Culture Device - Disclosed is a cell culture vessel that can prevent liquid leakage from the cell culture space and entry of particles containing microorganisms from outside the cell culture space, and that can prepare regenerated tissue in a manner that is safe and results in peace of mind. The cell culture vessel is mounted to a cell culture device, holds/cultures cells, and is characterized by being provided with: a culture solution holding section that holds a culture solution, a protruding structure section that is for supplying and discharging the aforementioned culture solution; and a culture solution duct that passes from the aforementioned protruding structure section to the aforementioned culture solution holding section. | 05-09-2013 |
20130189772 | MULTIWELL-PLATE REACTOR AND SYSTEM THEREFOR - A multiwell-plate reactor is provided herein for small scale cell culturing and fermenting. Advantageously, with the multiwell-plate reactor of the subject invention, a small scale cell culturing and fermenting process can be conducted with the fluid, such as a liquid nutrient or one or more gases, being introduced in a controlled manner. | 07-25-2013 |
20130210132 | BIOREACTOR AND METHOD - The bioreactor is for use in performing biological and/or biochemical reactions and includes a vessel, an agitator, a reaction assembly, and a harvesting outlet. The vessel of the bioreactor includes several ports including a mixing port, a reaction port, and a harvesting port. The agitator extends through the mixing port into the vessel while the harvesting outlet extends through the harvesting port and permits the withdrawal of reaction medium to another vessel. The reaction assembly extends through the reaction port into the vessel and has multiple components including a gas conduit adapted to introduce gas into a reaction medium in the vessel, a sampling device adapted to remove a portion of the reaction medium from the vessel without contamination of the remaining reaction medium, and an introduction conduit permitting the introduction of at least the reaction medium into the vessel. | 08-15-2013 |
20130267019 | CELL CULTURE INSERT - A cell culture device allows co-cultivation on both sides of a membrane and has an outer tubular body with upper end having an opening and lower end closed by the membrane, an inner surface and an outer surface, which can be colonized with biological material, a complementary tubular body whose inner diameter fits onto the outer diameter of the lower end and a hanger component with upper end and a lower end. A flange extends from the upper end and the outer diameter component fits the inner diameter of the outer tubular body. The outer tubular body in a first step is connected to the complementary tubular body to form a standing insert for a first cell cultivation, and in a second step wherein the outer tubular body is disengaged from the complementary tubular body and is attached to the hanger component for a second cell cultivation. | 10-10-2013 |
20130295660 | BIOREACTOR SYSTEM - A bioreactor or culture vessel for incubation of one or more cell cultures, tissue biopsies, cell clusters, tissue-like structures, “prototissues” or similar samples. The bioreactor comprises an incubation chamber, a liquid reservoir and conduction means separated from each other by semipermeable membranes. Specifically, the invention provides a humidity chamber design which simplifies the construction of the bioreactor. | 11-07-2013 |
20130295661 | Methods and Systems for Removing Undissolved Solids Prior to Extractive Fermentation in the Production of Butanol - A method and system for efficiently producing a fermentative product alcohol such as butanol utilizing in situ product extraction are provided. The efficiency is obtained through separating undissolved solids after liquefying a given feedstock to create a feedstock and prior to fermentation, for example, through centrifugation. Removal of the undissolved solids avoids problems associated with having the undissolved solids present during in situ production extraction, and thereby increases the efficiency of the alcohol production. | 11-07-2013 |
20130344587 | FOAM REMOVAL DEVICE IN AUTOMATIC CELL HANDLING ROBOT - A system for culturing a cell mass comprising:
| 12-26-2013 |
20140113364 | CELL CULTURE DEVICE - There is provided a cell culture device including: a cell chip receiving part receiving a cell chip; a drug storing part storing a drug; and a circulation part connecting the cell chip receiving part and the drug storing part to one another and circulating the drug therebetween. The cell culture device may allow for the observation or examination of a reaction between a cell and a drug in an environment similar to that of the inside of a body. | 04-24-2014 |
20140120609 | HUMIDITY CONTROL IN CHEMICAL REACTORS - Control of humidity in chemical reactors, and associated systems and methods, are generally described. In certain embodiments, the humidity within gas transport conduits and chambers can be controlled to inhibit unwanted condensation within gas transport pathways. By inhibiting condensation within gas transport pathways, clogging of such pathways can be limited (or eliminated) such that transport of gas can be more easily and controllably achieved. In addition, strategies for purging condensed liquid from chemical reactor systems are also described. | 05-01-2014 |
20140193897 | BIOREACTOR CONTAINER AND INTEGRITY CHECK METHOD FOR BIOREACTOR CONTAINERS - A bioreactor container comprising has an at least locally flexible wall and at least one container opening. The wall of the bioreactor container has a fluid-tight inner sheet, and an at least locally fluid-permeable or structured outer sheet. A method for testing the integrity of the bioreactor container also is provided. | 07-10-2014 |
20140234953 | FABRICATION OF VASCULARIZED TISSUE USING MICROFABRICATED TWO-DIMENSIONAL MOLDS - Methods and materials for making complex, living, vascularized tissues for organ and tissue replacement, especially complex and/or thick, structures, such as liver tissue is provided. Tissue lamina is made in a system comprising an apparatus having (a) a first mold or polymer scaffold, a semi-permeable membrane, and a second mold or polymer scaffold, wherein the semi-permeable membrane is disposed between the first and second molds or polymer scaffolds, wherein the first and second molds or polymer scaffolds have means defining microchannels positioned toward the semi-permeable membrane, wherein the first and second molds or polymer scaffolds are fastened together; and (b) animal cells. Methods for producing complex, three-dimensional tissues or organs from tissue lamina are also provided. | 08-21-2014 |
20140234954 | Methods and apparatus for independent control of product and reactant concentrations - A microreactor with a reaction chamber comprising two sub-chambers with reconfigurable volumes, an input conduit with input valve, an un-filtered output conduit with first output valve, and a filtered output conduit with a second output valve is used to perform a method to control a different dilution rate for cells and molecules in continuous culture bioprocesses. In preferred embodiments flow control is achieved using the difference in volume of the two sub-chambers. | 08-21-2014 |
20140308740 | MULTILAYER TISSUE CULTURE VESSEL - The present invention discloses a vessel for culturing cells which includes: a bottom, a top, a tubular neck, and, one or more shelves. The first shelf adjoins the top with the first shelf being located intermediate the bottom and the top. The bottom, the top and the one or more shelves collectively define an enclosed volume for culturing cells with the enclosed volume being accessible by the opening in the tubular neck. Advantageously, this vessel provides high volume cell culture in a manner that increases efficiency and reduces the cost of culturing cells. | 10-16-2014 |
20140342446 | PNEUMATIC ALTERNATING PRESSURE MEMBRANE CELL SEPARATION SYSTEM - Described are filtration systems that can be referred to as Pneumatic Alternating Cell Separators (PACS), useful components thereof in the form of assemblies or kits of parts that can be used to build the system, and use of the system for filtering fluids, for instance, in cell culture perfusion systems comprising a filter-containing chamber, an expansion chamber and a gas flow controller. | 11-20-2014 |
20140342447 | CASSETTE FOR STERILITY TESTING - The invention provides a device for growing cells—referred to as a cassette. The cell culturing device includes a housing that contains a lid having an optically clear window; a fluid distribution channel; a sample injection port fluidically connected to the fluid distribution channel; a base housing a porous media pad; and a media injection port fluidically connected to the media pad. The lid mates to the base to form a sterile seal; the fluid distribution channel is disposed over the media pad, which is viewable through the optical window; and sample fluid introduced into the fluid distribution channel is distributed evenly to the media pad, e.g., via a plurality of channels. The invention also provides kits that include cassettes of the invention and a tube set. | 11-20-2014 |
20140342448 | Bioengineering and Medical Modular System - The invention relates to bioengineering and medical modular systems for the realization of self-contained equipment for influencing biological media, cells, tissue and tissue-like structures as objects. | 11-20-2014 |
20140356939 | CELL SEPARATION CONTAINER - A cell separation container includes a collection chamber and a tissue holding chamber which are partitioned by a filter. The cell separation container includes a first air pressure adjuster configured to adjust the inflow and outflow of gas in the collection chamber and a second air pressure adjuster configured to adjust the inflow and outflow of gas in the tissue holding chamber. Thus, the inflow and outflow of the outside air and the gases in the collection chamber and the tissue holding chamber can be adjusted. In the cell separation container, switching between holding a treatment liquid in the tissue holding chamber and ejecting a treatment liquid to the collection chamber can be performed by adjusting the inflow and outflow of the outside air and the gas in the connection chamber. | 12-04-2014 |
20140377857 | INTEGRATED ELECTRO-BIOREACTOR - The disclosure provides a process and bioreactor that converts CO | 12-25-2014 |
20150050724 | SILAGE WASTE RECOVERY PROCESS, FACILITY, SYSTEM, AND PRODUCT - A silo of conventional construction is provided with a collection pan at its bottom to collect effluent. The effluent can be stored and/or processed. Processing can include separation of water to concentrate the effluent. The effluent can contain fermentation product, such as alcohol, generated within the silo prior to collection, and it can also be fermented after collection. Processed effluent can be handled safely without risk of contamination to ground water at the silo site. | 02-19-2015 |
20150056691 | Apparatus and methods for cell isolation - A unitary apparatus for isolating cells from adipose tissue including a lipid separation processor with a dispersing head equipped with a plurality of ports and a digestion chamber for dissociation of the constituent cells disposed in adipose tissue. The lipid separating apparatus is useful for the separation of lipids and adipocytes from a mixed cell population. A cell seeding chamber may be attached to the cell isolation apparatus. The components of the apparatus may be packaged in modular kit form. | 02-26-2015 |
20150072410 | DARK SHADE DYEING METHOD FOR MICROPOROUS TRACK ETCH MEMBRANES WITH LARGE PORES AND LOW POROSITY - Methods for dyeing of microporous track etched membranes are provided. In particular, these methods are suitable for dark shade dyeing of membranes having large pores with low porosity. Desirably, such methods provide dyed membranes wherein the membrane parameters are not significantly changed as compared to those prior to dyeing. Likewise, the resultant dyed membranes exhibit no negative influence on sensitive cell culture system applications. | 03-12-2015 |
20150307831 | APPARATUS AND METHOD FOR REMOVING MICROBIAL CONTAMINANTS FROM A FLOWING FLUID - Methods and apparatuses for removing microbial contaminants from a flowing fluid in a cell culture incubator are disclosed. Some embodiments of the invention provide a cell culture incubator including a chamber, an airflow passage through which gasses circulate within the chamber, a filter configured to filter gasses that flow through the airflow passage and chamber, and a blower for circulating gasses through the airflow passage, chamber and filter. The blower includes a structural component at least partially formed from an anti-microbial material. | 10-29-2015 |
20150344833 | MEDIUM EXCHANGE SYSTEM - Supply and discharge of a solution, such as a medium, in a cell culture bag are easily controlled. Provided is a system including a sac-like cell culture bag having a supply port for supplying a solution, such as a medium, to the inside and having a discharge port for discharging the solution, such as a medium, from the inside, wherein gate opening and closing means for opening and closing inner holes of the supply port and the discharge port are attached to the supply port and the discharge port, and the gate opening and closing means are controlled to easily exchange the medium or the like in the cell culture bag. | 12-03-2015 |
20150344931 | MICROBIAL DETECTION SYSTEM AND METHODS - The disclosure provides culture devices and methods for a microorganism in a sample. The devices include a base member, a cover sheet, an adhesive layer coupled to the base member or the cover sheet, and a cold water-soluble gelling agent disposed on the base member; wherein the devices are substantially optically transmissive when the gelling agent is hydrated with a clear liquid. Methods of use include detecting or enumerating microorganisms. The methods further provide for detecting a microorganism by detecting the presence or size of an abiogenic gas bubble in a culture device. | 12-03-2015 |
20150361386 | Biomimetic Device - Described herein are apparatus comprising: a first layer comprising a first microfluidic channel; a second layer comprising a second microfluidic channel; and a membrane for culturing cells; along with methods of making and using same. | 12-17-2015 |
20160010046 | APPARATUS FOR PRODUCING SUGAR SOLUTION | 01-14-2016 |
20160040109 | BIOREACTOR CONTAINER AND INTEGRITY CHECK METHOD FOR BIOREACTOR CONTAINERS - A bioreactor container comprising has an at least locally flexible wall and at least one container opening. The wall of the bioreactor container has a fluid-tight inner sheet, and an at least locally fluid-permeable or structured outer sheet. A method for testing the integrity of the bioreactor container also is provided. | 02-11-2016 |
20160108356 | MIXING AND FILTERING SYSTEM AND METHOD - An apparatus for growing and separating cells or micro carriers from fluid medium in an aseptic environment, has a sealed, air and liquid tight, container having a port to allow for the introduction of fluid, gas or components, a filter with a filtration medium mounted centrally around an axis extending through the container, a mixing assembly that rotates around the filtration medium to allow for suspension of media or agitation thereof, and the mixing assembly has vanes containing a magnetic unit in a lower portion thereof that allows for coupling to a stir plate for driving the vanes of the mixing assembly. The vanes are preferably suspended by a central bearing located above the filter, and preferably the vanes extend downward to proximate the bottom of the container to the same extent as the filter and a diptube located along the axis of the filter and vanes. | 04-21-2016 |
20160129441 | THERMAL REACTION DEVICE AND METHOD FOR USING THE SAME - An M×N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block. | 05-12-2016 |
20160144320 | FILTER DEVICE, MANUFACTURING DEVICE FOR CHEMICAL, AND OPERATION METHOD FOR FILTER DEVICE - In order to efficiently transport a filtration target liquid to a separation membrane module and to facilitate additional simplification of equipment in a filtration device including the separation membrane modules in which a plurality of lines thereof are disposed in series, a filtration device according to the present invention is a filtration device including a plurality of separation membrane modules each of which separates a liquid to be filtrated into a permeated liquid and a non-permeated liquid, in which the filtration device includes: a series non-permeated liquid flow channel that forms a series unit by connecting non-permeation sides of the plurality of separation membrane modules in series; and a parallel permeated liquid flow channel that forms a parallel unit by connecting permeation sides of the plurality of separation membrane modules in parallel. | 05-26-2016 |
20160152935 | BIOREACTOR SYSTEM AND SINGLE-USE CELL CULTURE CONTAINER FOR USE THEREIN | 06-02-2016 |
20160176743 | METHOD AND APPARATUS FOR CULTURE OF ANAEROBIC AMMONIUM OXIDIZER | 06-23-2016 |
20160186113 | CELL CULTURE APPARATUS FOR CO-CULTURE OF CELLS - A multilayered cell culture apparatus for the co-culturing of at least two cell types is disclosed. The cell co-culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between some cell culture chambers and the external environment. In addition, some cell culture chambers may have limited access to air creating relatively lower oxygen content cell culture chambers. The size of the apparatus, and location of an optional neck section, allows for its manipulation by standard automated assay equipment, further making the apparatus amenable to high throughput applications. | 06-30-2016 |
20160251607 | SYSTEM FOR RECYCLING WATER TO FACILITATE THE PRODUCTION OF ETHANOL | 09-01-2016 |