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32nd week of 2015 patent applcation highlights part 26
Patent application numberTitlePublished
20150218607MICROORGANISM FOR PRODUCTION OF CHEMICALS DERIVED FROM ACETYL-COA - Disclosed is an acetyl-CoA-producing microorganism, which is obtained by imparting malate thiokinase and malyl-CoA lyase enzymatic activities to a microorganism having none of the following (a), (b), (c) or (d), without imparting any of (a), (b), (c) or (d), or, even when one or more of (a), (b), (c) or (d) are imparted, not allowing the functions thereof to be exerted: (a) a carbon dioxide fixation cycle having an enzymatic reaction from malonyl-CoA to malonate semialdehyde or 3-hydroxypropionate, (b) a carbon dioxide fixation cycle having an enzymatic reaction from acetyl-CoA and CO2015-08-06
20150218608Compositions and Methods for Improvement of Ligation Yields - Methods and compositions are provided for increasing the ligation yields of polynucleotides in vitro.2015-08-06
20150218609EMULSION SYSTEMS AND EMULSION-BASED AMPLIFICATION OF NUCLEIC ACID - Methods for efficient and high throughput emulsion-based nucleic amplification are provided. In some aspects, emulsion mixtures are provided that require extremely low input energy (e.g., the energy generated by pipetting) to form emulsions that are effective for nucleic acid amplification. Efficient formulations for breaking emulsions are likewise provided.2015-08-06
20150218610PROTEIN PRODUCTION METHOD - This invention relates to a method for producing a protein of interest, comprising introducing a protein expression vector which comprises a gene fragment a gene fragment comprising a DNA encoding a protein of interest and a selectable marker gene and transposon sequences at both terminals of the gene fragment, into a suspension mammalian cell; integrating the gene fragment inserted between a pair of the transposon sequences, into a chromosome of the mammalian cell to obtain a mammalian cell capable of expressing the protein of interest; and suspension-culturing the mammalian cell; and a suspension mammalian cell capable of expressing the protein of interest.2015-08-06
20150218611METHOD FOR DESIGNING A DRUG REGIME FOR HIV-INFECTED PATIENTS - The instant disclosure describes a novel genotype and phenotype assay to elucidate and/or evaluate new potential HIV integrase inhibitors, but also currently approved and experimental compounds that target protease, reverse transcriptase, and RNaseH. This assay allows studying linked mutations and mutational patterns that occur under HAART and experimental therapies.2015-08-06
20150218612APPARATUS, SYSTEM AND METHOD FOR LIVE BACTERIA MICROSCOPY - A system for detecting microbial cells in a sample includes an apparatus configured to image at least one cell in the sample, and a cooling device. The apparatus includes a holder having an internal portion and an external portion which are configured so as to secure a membrane between the portions, and an imaging device disposed above the external portion and configured to permit examination of the at least one cell. The apparatus further includes a stage attachable to a stage platform configured to connect to a motor, and a projecting member projecting from an upper surface of the stage and configured to receive and exchange solution. The cooling device includes a thermoelectric cooling element and/or at least one tube configured to circulate a cooling medium beneath the stage so as to cool the sample.2015-08-06
20150218613REAGENT CARTRIDGE AND METHODS FOR DETECTION OF CELLS - An apparatus includes a housing and an actuator. The housing, which defines a reagent volume that can receive a reagent container, can be removably coupled to a reaction chamber. The housing includes a puncturer that defines a transfer pathway in fluid communication with the reagent volume. A delivery portion of the housing defines a delivery pathway between the transfer pathway and the reaction chamber when the housing is coupled to the reaction chamber. The actuator has a plunger portion disposed within the reagent volume. An engagement portion of the actuator can be manipulated to move the plunger portion within the reagent volume to deform the reagent container. The puncturer can pierce a frangible portion of the reagent container to convey a reagent from the reagent container into the reaction chamber via the transfer pathway and/or the delivery pathway.2015-08-06
20150218614METHODS AND COMPOSITIONS FOR DETECTING PATHOGENIC BACTERIA - The present invention encompasses methods and compositions for detecting pathogenic bacteria. Additionally, the present invention encompasses methods and compositions for catalyzing the dismutation of superoxide radicals. Further, the present invention encompasses methods for determining the antibiotic susceptibility of pathogenic bacteria.2015-08-06
20150218615METHODS FOR DETECTING ORGANISMS AND ENZYMATIC REACTIONS USING RAMAN SPECTROSCOPY AND AROMATIC COMPOUNDS COMPRISING PHOSPHATE - The present disclosure provides systems for the rapid and sensitive detection of organisms and molecules in samples. Reactants that produce Raman-active products are used in combination with Raman light scattering. Such compounds may comprise phosphates permitting the detection of phosphatases. The present disclosure can also be used to measure enzyme-kinetics.2015-08-06
20150218616Methods and Systems for Rapid Detection of Microorganisms using Infectious Agents - Disclosed herein are methods and systems for rapid detection of microorganisms in a sample, without culturing for enrichment of the microorganism. A modified bacteriophage is also disclosed which comprises a non-native indicator gene in the late gene region. The indicator product is not a fusion protein. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.2015-08-06
20150218617CYCLOPENTANE-PEPTIDE NUCLEIC ACIDS FOR QUALITATIVE AND QUANTITATIVE DETECTION OF NUCLEIC ACIDS - The invention concerns methods for detecting a nucleic acid of interest in a solution comprising (a) contacting a solution suspected of containing the nucleic acid of interest with a PNA capture probe and a PNA reporter probe; wherein (i) the PNA capture probe comprises at least two trans-cyclopentanes; (ii) the PNA reporter probe comprises at least six biotin groups; (iii) the PNA capture probe bound to a surface; and (iv) the PNA capture probe and the PNA reporter probe each comprise a nucleobase sequence that is complementary to different non-overlapping portions of the nucleic acid of interest; (b) detecting the presence of the PNA capture probe and the PNA reporter probe bound to the surface; wherein the nucleic acid of interest is detected when 1-1000 molecules of the nucleic acid of interest are present in the solution being tested.2015-08-06
20150218618Light Measurement Apparatus for Reaction Vessel and Light Measurement Method - The invention relates to a light measurement apparatus for a reaction vessel, and a light measurement method, whereby the optical state on the inside of a reaction vessel can be measured efficiently and reliably.2015-08-06
20150218619DEVICES AND METHODS FOR IMMOBILIZING NUCLEIC ACIDS - The present invention generally relates to devices and methods for immobilizing nucleic acids on a substrate. In certain embodiments, devices of the invention include a voltage source, and a substrate coupled to the voltage source, in which hydrophobicity of the substrate changes in response to an applied electric field and a surface of the substrate is coated with a substance that retains nucleic acids.2015-08-06
20150218620METHODS TO CAPTURE AND/OR REMOVE HIGHLY ABUNDANT RNAS FROM A HETEROGENOUS RNA SAMPLE - The invention is directed to a method of using DNA oligonucleotides as baits to capture and selectively remove highly abundant RNAs from a heterogeneous RNA sample for improved enrichment of other RNAs that are unrelated to the highly abundant RNAs.2015-08-06
20150218621CULTURE MEDIUM FOR FOOD POISONING BACTERIA, AND METHOD FOR DETECTING FOOD POISONING BACTERIA - A method for detecting food poisoning bacteria includes allowing a plurality of types of food poisoning bacteria including at least 2015-08-06
20150218622COMPOSITIONS AND METHODS FOR DETECTION OF STAPHYLOCOCCUS AUREUS - The present invention relates to methods for the rapid detection of the presence or absence of 2015-08-06
20150218623COMPOSITIONS AND METHODS FOR DETECTION OF STAPHYLOCOCCUS AUREUS - The present invention relates to methods for the rapid detection of the presence or absence of 2015-08-06
20150218624COMPOSITIONS AND METHODS FOR DETECTION OF STAPHYLOCOCCUS AUREUS - The present invention relates to methods for the rapid detection of the presence or absence of 2015-08-06
20150218625COMBINATION OF DSDNA BINDING DYE AND PROBES FOR CHARACTERIZATION OF SSDNA SEQUENCES - This invention includes methods for analyzing single-stranded nucleic acid sequences, either RNA sequences or DNA sequences (ssDNA) utilizing dyes that fluoresce when associated with double strands, so-called DNA binding dyes or dsDNA-dyes. Methods according to this invention utilize a dsDNA-dye in combination with one or more hybridization probes that hybridize to a target nucleic acid sequence and that are labeled with a non-fluorescent quencher moiety, for example, a Black Hole quencher.2015-08-06
20150218626MULTIPLEX NUCLEIC ACID ANALYSIS - Here provided is a method for multiplex nucleic acid analysis. The method includes steps of hybridizing sets of probes to target nucleic acids in a sample, ligating the hybridized probes, amplifying the ligated probes, and assaying the amplification products to determining the presence, absence, or quantity of the target nucleic acids in the sample. The multiplexity is made available in part by adding detectable moieties and inserting stuffer sequences in primers so that amplification products may be identified on the basis of the detectable moieties and fragment sizes. Also provided is a sensitive method of detecting small copy number changes by measuring the copy number of a plurality of target sites in the nucleic acid in a test sample in comparison to a control sample and then determining the copy number of the nucleic acid based on the measured copy number of the plurality of target sites. Further provided is a kit for multiplex nucleic acid analysis and for small copy number change determination.2015-08-06
20150218627SINGLE LABEL COMPARATIVE HYBRIDIZATION - The present invention provides methods of detecting and mapping chromosomal or genetic abnormalities associated with various diseases or with predisposition to various diseases, or to detecting the phenomena of large scale copy number variants. In particular, the present invention provides advanced methods of performing array-based comparative hybridization that allow reproducibility between samples and enhanced sensitivity by using the same detectable label for both test sample and reference sample nucleic acids. Invention methods are useful for the detection or diagnosis of particular disease conditions such as cancer, and detecting predisposition to cancer based on detection of chromosomal or genetic abnormalities and gene expression level. Invention methods are also useful for the detection or diagnosis of hereditary genetic disorders or predisposition thereto, especially in prenatal samples. Moreover, invention methods are also useful for the detection or diagnosis of de novo genetic aberrations associated with post-natal developmental abnormalities.2015-08-06
20150218628TARGET PARTICLE DETERMINING METHOD - Provided a target particle determining method of detecting a non-light emitting particle, including the steps of: (a) combining a non-light emitting observation particles, a solid phase carriers and a target particles in a first solution; (b) forming a complex of the target particle bound with a non-light emitting observation particle and a solid phase carrier; (c) removing the observation particles that are not bound to the target particles; (d) separating observation particles from solid phase carriers; (e) dispersing the separated observation particles in a second sample solution; (f) detecting the separated observation particles; and (g) determining the target particles that correspond to each of the detected observation particles in step (f).2015-08-06
20150218629ENZYME CONSTRUCT - The invention relates to methods using constructs comprising a helicase and an additional polynucleotide binding moiety. The helicase is attached to the polynucleotide binding moiety and the construct has the ability to control the movement of a polynucleotide. The constructs can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.2015-08-06
20150218630DNA SEQUENCING METHODS AND DETECTORS AND SYSTEMS FOR CARRYING OUT THE SAME - In some embodiments, an analyte detection system is provided that includes a nanochannel, an electrode arrangement, and a plurality of nanoFET devices disposed in the nanochannel. A plurality of nucleic acid base detection components can be used that include a plurality of nanopores, a plurality of nanochannels, a plurality of hybridization probes, combinations thereof, and the like. According to other embodiments of the present teachings, different coded molecules are hybridized to a target DNA molecule and used to detect the presence of various sequences along the target molecule. A kit including mixtures of coded molecules is also provided. In some embodiments, devices including nanochannels, nanopores, and the like, are used for manipulating movement of DNA molecules, for example, in preparation for a DNA sequencing detection. Nanopore structures and methods of making the same are also provided as are methods of nucleic acid sequencing using the nanopore structures. Surface-modified nanopores are provided as are methods of making them. In some embodiments, surfaced-modified nanopores for slowing the translocation of single stranded DNA (ssDNA) through the nanopore are provided, as are nanopores configured to detect each of a plurality of different bases on an ssDNA strand.2015-08-06
20150218631METHODS OF FETAL ABNORMALITY DETECTION - Methods and kits for selectively enriching non-random polynucleotide sequences are provided. Methods and kits for generating libraries of sequences are provided. Methods of using selectively enriched non-random polynucleotide sequences for detection of fetal aneuploidy are provided.2015-08-06
20150218632SYSTEM AND METHODS FOR NUCLEIC ACID SEQUENCING OF SINGLE MOLECULES BY POLYMERASE SYNTHESIS - This invention relates to improved methods for sequencing and genotyping nucleic acid in a single molecule configuration. The method involves single molecule detection of fluorescent labeled PPi moieties released from NTPs as a polymerase extension product is created.2015-08-06
20150218633Methods and Systems for Processing Polynucleotides - The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.2015-08-06
20150218634USE OF HLA-B*1301 ALLELE - The present invention discloses uses of a HLA-B*1301 allele, comprising: 1) a use of a substance for detecting whether a person has the HLA-B*1301 allele in preparation of a product for evaluating a risk of adverse drug reactions in response to dapsone in the person; 2) a method for detecting or evaluating a risk of adverse drug reaction in response to dapsone in a person, comprising detecting whether the person has the HLA-B*1301 allele, wherein, a person with LA-B*1301 allele suffers a higher risk of adverse drug reaction upon being administered dapsone, as compared with a person without HLA-B*1301 allele, and a person with LA-B*1301 alleles at both chromosomes of a pair of homologous chromosomes suffers a higher risk of adverse drug reaction upon being administered dapsone, as compared with a person with HLA-B*1301 allele at only one of a pair of homologous chromosomes.2015-08-06
20150218635METHOD FOR OBTAINING DATA THAT CAN BE USED FOR THE DIAGNOSIS AND PROGNOSIS OF NEUROSENSORY HYPOACUSIS - A method for obtaining useful data for the determination of an individual's risk of suffering from severe sensorineural hearing loss, preferably in Ménière's disease, primers useful in the determination and kit comprising same.2015-08-06
20150218636Mutations In Calmodulin Genes - The present invention relates to an isolated polynucleotide encoding at least a part of calmodulin and an isolated polypeptide comprising at least a part of a calmodulin protein, wherein the polynucleotide and the polypeptide comprise at least one mutation associated with a cardiac disorder. The present invention also relates to a method for determining whether an individual has an increased risk of contracting a cardiac disorder, a method for diagnosing a cardiac disorder, method for treatment of an individual having a cardiac disorder, method for identifying a compound, capable of enhancing the binding of calmodulin to ryanodine receptor 2 and use of such compound in a treatment of an individual having a cardiac disorder. The invention further provides a kit that can be used to detect specific mutations in calmodulin encoding genes.2015-08-06
20150218637GENETIC MARKERS FOR PREDICTING RESPONSIVENESS TO FGF-18 COMPOUND - This application is directed to the use of biomarkers for predicting the sensitivity to treatment with an FGF-18 compound in a patient having a cartilage disorder, such as osteoarthritis, cartilage injury, fractures affecting joint cartilage or surgical procedures with impact on joint cartilage (e.g., microfracture), in order to reduce the risk of adverse events and increase the overall benefit after therapy.2015-08-06
20150218638METHODS FOR ASSESSMENT OF PEPTIDE-SPECIFIC IMMUNITY - Embodiments of the invention relate generally to methods for assessing the immune response related to a specific antigen or antigens. In several embodiments, the methods described herein are used to enable a recommendation for a particular type of therapy against a particular antigen, such as a foreign infectious agent or cancer cell. In several embodiments, the methods disclosed herein enable the ongoing monitoring of a subject's immune function.2015-08-06
20150218639BIOMARKERS PREDICTIVE OF PREDISPOSITION TO DEPRESSION AND RESPONSE TO TREATMENT - The present invention relates generally to the identification of subjects with a predisposition to recurrent depression, predicting a subject's responsiveness to therapy, and determining whether a subject has remitted from depression following therapy. In particular, provided herein are biomarkers, methods, and kits for such uses.2015-08-06
20150218640BIOMARKER SIGNATURE METHOD, AND APPARATUS AND KITS THEREFOR - The present invention discloses methods, kits, and apparatus as well as reagents and compositions associated therewith for deriving an indicator for use in diagnosing the presence, absence or degree of at least one condition in a biological subject or in prognosing at least one condition in a biological subject. Also disclosed is a biomarker signature for use in diagnosing the presence, absence or degree of at least one condition in a biological subject or in prognosing at least one condition in a biological subject. The present invention further discloses methods, kits and apparatus, as well as reagents and compositions associated therewith, for identifying biomarkers for use in a biomarker signature.2015-08-06
20150218641METHOD FOR PROGNOSTICATING THE CLINICAL RESPONSE OF A PATIENT TO B-LYMPHOCYTE INHIBITING OR DEPLETING THERAPY IN INTERFERON-DRIVEN DISEASES SUCH AS SLE - Described are methods for predicting a clinical response to B-lymphocyte inhibiting or depleting therapies (BCIDT) using expression levels of genes of the Type I INF pathway. In another aspect, disclosed is a method for evaluating a pharmacological effect of a treatment with B-lymphocyte inhibiting or depleting therapy. More particularly, it relates to methods for prognosticating the clinical response of a patient to treatment with a soluble BCID or TCID agent, the method including obtaining at least two samples from the patient wherein a first sample has not been exposed to a soluble BCID or TCID agent and wherein at least a second sample has been exposed to a soluble BCID or TCID agent, determining the level of an IFN (preferably type I) response in the at least two samples, comparing the level of the IFN (preferably type I) response in the first sample with the level of the IFN (e.g., type I) response in the at least second sample and prognosticating the clinical response from the comparison.2015-08-06
20150218642PRIMER GROUP FOR DETECTING CPG ISLAND METHYLATION OF P16 GENE USING METHYLATION- SPECIFIC FLUORESCENCE TECHNIQUE - The invention provides a primer group for detecting CpO island methylation of p16 gene using methylation specific fluorescence technique. The primer group comprises a pair of oligonucleotide primers and a fluorescence-labeled probe. Said oligonucleotide primer pair has base sequence represented by SEQ ID NO.1 and SEQ ID NO.2. Said fluorescence-labeled probe has base sequence represented by SEQ ID NO.3 or SEQ NO.4.2015-08-06
20150218643DIFFERENTIAL METHYLATION LEVEL OF CPG LOCI THAT ARE DETERMINATIVE OF KIDNEY CANCER - The present disclosure provides for and relates to the identification of novel biomarkers for diagnosis and prognosis of kidney cancer. The biomarkers of the invention show altered methylation levels of certain CpG loci relative to normal kidney tissue, as set forth.2015-08-06
20150218644THERAPY WITH CLOSTRIDIUM PERFRINGENS ENTEROTOXIN TO TREAT OVARIAN AND UTERINE CANCER - The invention discloses high levels of receptors for 2015-08-06
20150218645METHODS AND PRODUCTS RELATED TO TARGETED CANCER THERAPY - The invention relates to methods and related products for treatment and determining modes of treatment for cancer or prognosis of cancer. Preferably the methods are related to the induction of CD80 in p53 responsive cancer cells.2015-08-06
20150218646METHODS, KITS AND COMPOSITIONS FOR PROVIDING A CLINICAL ASSESSMENT OF PROSTATE CANCER - The present invention relates to prostate cancer signatures which are useful for providing a clinical assessment of prostate cancer from a biological sample of a subject. By performing initial gene expression studies on urine samples from prostate cancer and non-prostate cancer subjects, and using the PCA3/PSA prostate cancer test as a performance benchmark, the present inventors have surprisingly discovered multiple signatures that are informative in urine-based prostate cancer tests, as well as in tissue-based tests. The signatures relate to combinations of at least two prostate cancer markers whose expression pattern in urine has been validated as being associated (either positively or negatively) with a clinical assessment of prostate cancer. The prostate cancer markers can be used in conjunction with bioinformatics approaches to generate a prostate cancer score, which correlates with a clinical assessment of prostate cancer. Methods, kits and compositions relating to the aforementioned signatures are also described.2015-08-06
20150218647BIOMARKERS FOR IDENTIFYING ESOPHAGEAL CANCER PATIENTS FOR TREATMENT WITH AN ANTI-EGFR DRUG - The present invention provides methods for the treatment of esophageal cancer patients as well as the identification and selection of esophageal cancer patients for treatment with an anti-EGFR agent treatment including anti-EGFR antibody treatment, e.g., cetuximab treatment. In some embodiments, the drug is against a heterodimer formed by EGFR and another member of the ErbB receptor family such as EfbB2/Her2/neu.2015-08-06
20150218648METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS IN BREAST CANCER - The present invention relates to methods for diagnosing breast cancer; methods for assigning risk of reoccurrence of breast cancer; methods for assigning risk of mortality due to breast cancer, methods of monitoring breast cancer; methods of staging breast cancer; and various devices and kits adapted to perform such methods. These methods comprise measurement gene expression from one or more protein fatty acyl transferase genes in a tissue sample, and preferably in a tumor sample, from the patient.2015-08-06
20150218649BIOMARKER ASSOCIATED WITH RISK OF MELANOMA REOCCURRENCE - The present invention provides a method of predicting the risk of reoccurrence of melanoma in a patient from whom melanoma tissue was previously removed which comprises the following: 2015-08-06
20150218650METHODS AND KITS FOR SCREENING PATIENTS WITH A CANCER - A method for screening patients with a cancer comprising i) determining in a tumor sample obtained from a patient an expression level ELA2015-08-06
20150218651USE OF DNA IN CIRCULATING EXOSOMES AS A DIAGNOSTIC MARKER FOR METASTATIC DISEASE - The present invention is directed to methods of diagnosing, prognosing, and monitoring cancer in a subject. These methods involves selecting a subject having cancer, and obtaining, from the selected subject, a sample containing exosomal DNA. The presence or absence of one or more mutations in BRAF and/or EGFR is detected in the exosomal DNA sample from the subject, and a diagnosis and/or prognosis of the cancer is given based on the detection of the one or more mutations in BRAF and/or EGFR. The present invention further relates to methods of treating a subject having cancer and/or monitoring a subject response to therapy based on the detection of one or more mutations in BRAF and/or EGFR in the exosomal DNA sample.2015-08-06
20150218652METHODS FOR DIAGNOSIS AND TREATMENT OF CANCER - Disclosed are markers, methods and assay systems for the identification of patients suspected of having lung cancer and/or cancer patients who are predicted to respond, or not respond to the therapeutic administration of specific chemotherapeutic regimens. Particularly, the invention provides a testing paradigm based on tumor cell samples to select cancer patients who will benefit from chemotherapy including one or more kinase inhibitor(s), as well as a paradigm to select cancer patients who will not benefit from such chemotherapy regimen.2015-08-06
20150218653METHOD OF DETERMINING THE PRESENCE OR ABSENCE OF A TARGET NUCLEIC ACID IN A CELL SAMPLE - A method of determining the presence or absence of a target nucleic acid in a cell sample, said method comprising: a) contacting a surface comprising anion exchange moieties with the sample under conditions suitable to induce binding between the cells and said surface; b) separating the surface with the bound cells from the remaining sample to collect the cells; c) releasing nucleic acids from the cells and d) generating a hybrid between the target nucleic acid and a probe specific for the target nucleic acid e) detecting the presence or absence of the hybrid. The present invention is provides a rapid and automatable method, wherein cells, such as epithelial cells originating from cervical swab samples, are collected from the surrounding liquid medium, such as a liquid based cytology medium, by binding them to an anion exchange surface. The cells bind directly with high affinity and quick kinetics to the anion exchange surface which preferably is provided by magnetic particles carrying anion exchange moieties. The cells that are bound to the anion exchange surface can be easily separated from the surrounding medium and can be directly resuspended in a composition that is suitable for a subsequent hybrid capturing assay which is performed in step d) to detect e. g. pathogen nucleic acids such as HPV nucleic acids.2015-08-06
20150218654METHODS FOR PREDICTING MULTIPLE MYELOMA TREATMENT RESPONSE - The present invention relates to a method of testing whether a patient suffering of multiple myeloma will respond or not to a DNA methyltransferase inhibitor (DNMTi) comprising: i. determining the expression level (ELi) of several genes G2015-08-06
20150218655BIOMARKERS FOR PROSTATE CANCER PROGNOSIS - Described are embodiments related to prostate cancer biomarkers, agents, and systems for detecting and targeting the same, and associated prostate cancer diagnostic and prognostic methods.2015-08-06
20150218656METHODS FOR DETECTION AND DIAGNOSIS OF A LYMPHOID MALIGNANCY USING HIGH THROUGHPUT SEQUENCING - Methods and compositions are provided for detection and diagnosis of a lymphoid malignancy using high throughput sequencing of rearranged T cell receptor DNA sequences.2015-08-06
20150218657REAL-TIME PCR ASSAY FOR DETECTION OF BABESIA MICROTI AND CLINICAL UTILIZATION IN DIAGNOSIS AND TREATMENT OF BABESIOSIS - Methods and kits are provided for detecting 2015-08-06
20150218658MOLECULAR MARKERS LINKED TO PPO INHIBITOR TOLERANCE IN SOYBEANS - This invention relates generally to the detection of genetic differences among soybeans. More particularly, the invention relates to soybean quantitative trait loci (QTL) for tolerance to protoporphyrinogen oxidase inhibitors, to soybean plants possessing these QTLs, which map to a novel chromosomal region, and to genetic markers that are indicative of phenotypes associated with protoporphyrinogen oxidase inhibitor tolerance. Methods and compositions for use of these markers in genotyping of soybean and selection are also disclosed.2015-08-06
20150218659COTTON TRANSGENIC EVENT MON 88701 AND METHODS OF USE THEREOF - The invention provides cotton event MON 88701, and plants, plant cells, seeds, plant parts, and commodity products comprising event MON 88701. The invention also provides polynucleotides specific for event MON 88701 and plants, plant cells, seeds, plant parts, and commodity products comprising polynucleotides specific for event MON 88701. The invention also provides methods related to event MON 88701.2015-08-06
20150218660COMPOSITIONS AND METHODS FOR ENHANCING RESISTANCE TO NORTHERN LEAF BLIGHT IN MAIZE - The invention relates to methods and compositions for identifying and selecting maize plants with enhanced resistance to northern leaf blight. Maize plants generated by the methods of the invention are also a feature of the invention.2015-08-06
20150218661METHOD USING GLYCAN IMMOBILIZED METAL NANOPARTICLES FOR EARLY HIV-1 DETECTION - Disclosed is a method used thereof for detecting HIV-1 in a saliva sample at early stages of viral infection. The method comprises the steps of: (A) providing glycan immobilized metal nanoparticles which can recognize HIV-1 and diluting the saliva sample to half of the concentration; (B) contacting the glycan immobilized metal nanoparticles with the saliva sample and a mixture is obtained, wherein a volume ratio of the glycan immobilized metal nanoparticles to the saliva sample is 1:49, wherein the HIV-1 in the saliva sample is approximately 0.1 to 10 copies/ml; (C) concentrating the mixture; and (D) determining HIV-1 in the concentrated mixture by a detecting method; wherein each of the glycan immobilized metal nanoparticles includes a ligand-conjugate, the ligand-conjugate has a linker compound, the linker compound has a formula (1).2015-08-06
20150218662METHOD FOR DETECTING AND TYPING NUCLEIC ACIDS OF PATHOGENIC MICROORGANISM WITHOUT AMPLIFICATION - The invention discloses a method for directly detecting and typing nucleic acids of pathogenic microorganism without amplification and a related kit, the invention achieves detecting and typing nucleic acids of pathogenic microorganism without amplification by the combination of multiprobe and the layer by layer assembly of fluorescence quantum dots. The method according to the invention can directly detect a nucleic acid with low concentration without amplification; the multiprobe prevents the false positives which are likely to occur in the process of signal amplification and thus increases detection accuracy. Such technology can achieve the real-time detection and simultaneous genotyping of pathogenic microorganisms with rapid speed and low cost.2015-08-06
20150218663METHODS AND SYSTEMS FOR PRODUCING SUGARS FROM CARBOHYDRATE-RICH SUBSTRATES - A method for producing sugars from lignocellulosic biomass is provided. Lignocellulosic biomass is composed of lignocellulosic fibers which are hollow and primarily contain cellulose, hemicellulose and lignin. Lignin is concentrated in the outer fiber wall and glues the fibers into bundles, but the inner fiber wall has a much lower concentration of lignin and has more easily accessible cellulose and hemicellulose. This method uses vacuum infusion to infuse homogeneous reagents into the lumen (hollow center) of lignocellulosic fibers to hydrolyze the hemicellulose and cellulose to produce sugars and oligomers, and then uses cycles of vacuum pressure to pump these homogeneous reagents and sugars and oligomers into and out of the lumen. Some types of reagents are dilute acids, cellulase enzymes, hemicellulase enzymes, Fenton or Fenton-like reagents, and hydrogen peroxide. These reagents are homogenized by mixing the reagents with process water using turbulent mixing to produce a homogeneous reagent.2015-08-06
20150218664DISPLACEMENT OF SCRAPING ROLLERS - An apparatus is disclosed for processing the skin side (2015-08-06
20150218665SOFTENING PROCESS AND SYSTEM FOR ROLL GOODS - A method and system for softening a high-density leather finished roll good and other stiff high density roll goods may include adjusting a first horizontal distance between a first impact grid and a first tunnel opening and adjusting a second horizontal distance between a second impact grid and a second tunnel opening based on the stiffness of the roll good. The method also may include introducing the roll good in a first direction through the air tunnel until the roll good hits the second impact grid, and introducing the roll good in an opposite direction through the air tunnel until the roll good hits the first impact grid. The method may further include passing the roll good through a cooling chamber.2015-08-06
20150218666BLAST FURNACE INSTALLATION - This blast furnace installation is configured such that when pulverized coal, which has been prepared by pulverizing high-grade coal, is pneumatically conveyed into a supply tank by a combustion gas, pulverized coal, which has been prepared by drying, dry-distilling, cooling, and pulverizing low-grade coal with a drying device, a dry-distillation device, a cooling device, and a pulverization device, is supplied from a storage tank by a feeder and pneumatically conveyed into the supply tank by a nitrogen gas, and then the pulverized coals in the supply tank are pneumatically conveyed from a supply line into an injection lance by a carrier gas, a control unit controls the feeders so as to gradually increase the supply amount of pulverized coal while maintaining the total amount of supply amount of pulverized coal and supply amount of pulverized coal to be supplied to the tuyere at a prescribed amount.2015-08-06
20150218667Method and Device for Measuring Levels of Cast Iron and Slag in a Blast Furnace - The present invention relates to a method for measuring the liquid-metal surface level (2015-08-06
20150218668Ferritic Lightweight High-Strength Steel Sheet Having Excellent Stiffness and Ductility, and Method of Manufacturing the Same - Provided is a ferritic lightweight high-strength steel sheet having excellent stiffness and ductility and a method of manufacturing the same. The steel sheet including 0.02 wt % to 0.1 wt % of carbon (C), 4 wt % to 15 wt % of manganese (Mn), 4 wt % to 10 wt % of aluminum (Al), 2.0 wt % or less (excluding 0) of silicon (Si), 0.01 wt % to 0.3 wt % of titanium (Ti), 0.005 wt % to 0.2 wt % of antimony (Sb), and iron (Fe) as well as unavoidable impurities as a remainder, and having a value of 0.25×Ti/C ranging from 0.17 to 1.0 and a value of Mn/Al×Log(C×Ti×10000) ranging from 1.0 to 10.2015-08-06
20150218669METHOD FOR LEACHING NICKEL, COBALT AND IRON FROM A NICKEL LATERITE ORE - We propose a method for leaching nickel, cobalt and iron from a nickel laterite ore, characterized in that the nickel laterite ore is brought into contact with a solution of sulphuric acid and urea mixture. In this way, there is provided a method for efficient recovery of nickel and cobalt from nickel laterite ores where leaching in sulphuric acid/urea mixture can be completed in about less than 1 hour.2015-08-06
20150218670EXTRACTION SOLVENT FOR EXTRACTING METALLIC ELEMENTS, METHOD FOR PRODUCING SAME, AND METHOD FOR RECOVERING METALLIC ELEMENTS - The present invention provides an extraction solvent for extracting metallic elements that is characterized in that: the total concentration of chlorine (Cl2) and hypochlorous acid (HOCl) is from 20 to 1000 ppm; chlorine (Cl2) and hypochlorous acid (HOCl) are included at a molar ratio of 1:1 to 1:11; the oxidation-reduction potential is from 1100 to 1400 mV; and the pH is from 1.7 to 3.7. The present invention also provides a method for producing said extraction solvent, and a method for recovering metallic elements by using said extraction solvent.2015-08-06
20150218671METHOD FOR RECOVERING PRECIOUS METAL FROM METAL CARRIER CATALYST - A method for recovering precious metal held in a metal carrier catalyst from said catalyst, that includes a step (1) in which the catalyst is heated in a nitric acid solution, and a step (2) in which the post-step (1) catalyst is heat treated in a sulfuric acid solution.2015-08-06
20150218672PROCESS FOR RECOVERING METAL VALUES FROM OXIDES OF MANGANESE-CONTAINING MATERIALS - An improved method for treating manganese-containing materials, such as nodules recovered by undersea mining, including reacting the materials with ammonia, and leaching with a mineral acid, and to methods for recovering valuable constituents from such nodules, especially manganese, cobalt, nickel, iron, copper, titanium, vanadium, cerium, and molybdenum. A method for the production of nitrate products is also disclosed.2015-08-06
20150218673AL-NB-B MASTER ALLOY FOR GRAIN REFINING - A method of producing a master alloy for refining the grain size of a bulk alloy comprises the step of providing an Al—B alloy and adding Nb in elemental form to form an Al—Nb—B master alloy. The Al—B alloy may be prepared by providing an Al—B alloy with a higher boron content than is required and diluting it with elemental aluminium.2015-08-06
20150218674Fastening Copper Alloy - A copper alloy for fastening wherein the alloy has a structure of a mixture of α-phase and a β-phase; and wherein the alloy has a composition represented by the general formula: Cu2015-08-06
20150218675HIGH-TEMPERATURE TiAl ALLOY - The present invention relates to a TiAl alloy for use at high temperatures having the main constituents titanium and aluminum and having a proportion of aluminum of greater than or equal to 30 at. % and a matrix composed of β phase and precipitates of ω phase embedded in the matrix, with the β phase and the ω phase together making up at least 55% by volume of the microstructure, and also a process for the production thereof and the use thereof.2015-08-06
20150218676METAL-CARBON COMPOSITE MATERIAL, METHOD FOR PRODUCING METAL-CARBON COMPOSITE MATERIAL AND SLIDING MEMBER - Provided are a metal-carbon composite material having good workability and a high carbon content and a method for producing the same. The metal-carbon composite material (2015-08-06
20150218677ALUMINUM ALLOY SHEET FOR AUTOMOBILE PART - Provided is a 7000-series aluminum alloy sheet that is for an automobile part and that is provided with both strength and stress corrosion cracking resistance. The cold-rolling rate and solution treatment conditions are controlled of an Al—Zn—Mg alloy sheet having a specific composition and produced by means of a conventional method. Also, the structure has a low average crystal size, an average fraction of low-angle grain boundaries at an inclination angle of 5-15° of at least 15%, and an average fraction of high-angle grain boundaries at an inclination angle exceeding 15° of 15-50%. Alternatively, there is a specific aggregate structure having a low average crystal size, and a total area ratio of the specific orientation of the Brass orientation, S orientation, Cu orientation, and the like of at least a set amount.2015-08-06
20150218678AL-ZN ALLOY FOR DIE CASTING HAVING BOTH HIGH STRENGTH AND HIGH THERMAL CONDUCTIVITY - The present invention relates to an aluminum alloy which has excellent thermal conductivity as well as high castability and satisfactory tensile characteristics, and is thus applicable to various kinds of structural products that require heat dissipation characteristics. According to the present invention, the aluminum alloy for die casting includes 5.5-8.5 wt % of zinc (Zn), 0.5-3.0 wt % of magnesium (Mg), 0.45-1.5 wt % of iron (Fe), and the remainder consisting of aluminum (Al) and inevitable impurities.2015-08-06
20150218679ALUMINUM ALLOY AUTOMOBILE PART - Provided is an automobile part comprising a 7000-series aluminum alloy sheet and provided with both strength and stress corrosion cracking resistance. The automobile part is configured from a 7000-series aluminum alloy sheet having a specific composition, and after artificial aging processing, the grain size distribution of precipitates evaluated by means of a small angle x-ray scattering among the crystal grains of the aluminum alloy plate and the normalized dispersion of the grain size distribution are controlled, resulting in being simultaneously provided with high strength in the form of an 0.2% proof stress of at least 350 MPa, high ductility, and SCC resistance. Also, the automobile part is configured from a 7000-series aluminum alloy sheet having a specific composition, and after artificial aging processing, a specific number density of nanosized precipitates are caused to be present as measured by a transmission electron microscope at 300,000× magnification in the crystal grains of the aluminum alloy plate, resulting in being simultaneously provided with high strength in the form of an 0.2% proof stress of at least 350 MPa, high ductility, and SCC resistance.2015-08-06
20150218680WROUGHT MAGNESIUM ALLOY - An extrusion of a magnesium-based alloy consisting of, by weight:2015-08-06
20150218681BORON-CONTAINING ALUMINUM MATERIAL AND METHOD FOR MANUFACTURING THE SAME - This boron-containing aluminum material is obtained by carrying out the following: a mixed powder, obtained by mixing a boride powder containing first boride particles, second boride particles and particles of unavoidable impurities with an aluminum powder or aluminum alloy powder that forms a matrix, is filled into in a square aluminum pipe having a prescribed shape and then rolled by using pressure rolls the gap between which is adjusted.2015-08-06
20150218682Machine Structural Steel Material Having Low Heat-Treatment Deformation - There is provided a steel material with small heat treatment deformation, comprising a machine structural steel used for components for power transmission, such as gears and shafts used in automobiles, industrial machines, and the like. In the steel material, the Ms point of the steel material comprising a machine structural steel, comprising in mass %: C: 0.20 to 0.30%; Si: 0.10 to 1.50%; Mn: 0.10 to 1.20%; P: 0.030% or less; S: 0.030% or less; Cr: 1.30 to 2.50%; Cu: 0.30% or less; Al: 0.008 to 0.300%; O: 0.0030% or less; and N: 0.0020 to 0.0300%; and the balance Fe and unavoidable impurities, is 460° C. or less; a ratio (J9/J1.5) of hardness J9 at a distance of 9 mm from the quenched end of the steel material to hardness J1.5 at a distance of 1.5 mm from the quenched end of the steel material, as measured by Jominy end quenching method, is in a range of from 0.70 to 0.85; and a ratio (J11/J1.5) of hardness J11 at a distance of 11 mm from the quenched end of the steel material to hardness J1.5 is in a range of from 0.67 to 0.78.2015-08-06
20150218683FERRITIC STAINLESS STEEL - A ferritic stainless steel having a good thermal fatigue property and oxidation resistance while minimizing the contents of Mo, W, and Nb which are expensive elements and minimizing the content of Cu which deteriorates oxidation resistance and workability.2015-08-06
20150218684Cold-Rolled Flat Steel Product and Method for the Production Thereof - A cold-rolled flat steel product where Rm≧1400 MPa and A80≧5% and also a method for producing such product. The product includes, in addition to Fe and unavoidable impurities (in wt. %), 0.10-0.60% C, 0.4-2.5% Si, ≦3.0% Al, 0.4-3.0% Mn, ≦1.0% Ni, ≦2.0% Cu, ≦0.4% Mo, ≦% Cr, ≦1.5% Co, ≦0.2% Ti, ≦0.2% Nb, ≦0.5% V. The microstructure includes (in vol. %) ≧20% bainite, 10-35% residual austenite and martensite as the remainder. A slab, thin slab or a cast strip having said composition, is hot-rolled to form hot strip with a hot-rolling end temperature ≧830° C., coiled at a coiling temperature ≦560° C., cold-rolled at ≧30% reduction and heat-treated by firstly being heated to an annealing temperature ≧800° C., then being cooled at a cooling rate of ≧8° C./s to a holding temperature of 470° C. to greater than the martensite start temperature and then being held at the holding temperature until at least 20 vol. % bainite is present in the microstructure.2015-08-06
20150218685NON-HEAT TREATED STEEL - A non-heat treated steel according to the present invention includes, as steel composition, by mass %, 0.20 to 0.60% of C, 0.50 to 2.0% of Si, 0.20 to 2.0% of Mn, 0.010 to 0.15% of P, 0.010 to 0.15% of S, 0.10 to 0.50% of V. 0.002 to 0.02% of N, and a balance consisting of Fe and impurities, in which, when a ratio of a maximum value of a V content in the steel to an average value of the V content in the steel in a cross section of the steel is defined as a segregation ratio of V, the segregation ratio of V is 1.0 or more and less than 3.0.2015-08-06
20150218686Ultra High Strength Alloy for Severe Oil and Gas Environments and Method of Preparation - A high strength, corrosion resistant alloy suitable for use in oil and gas environments includes, in weight percent: 0-15% Fe, 18-24% Cr, 3-9% Mo, 0.05-3.0% Cu, 4.0-6.5% Nb, 0.5-2.2% Ti, 0.05-1.0% Al, 0.005-0.040% C, balance Ni plus incidental impurities and deoxidizers. A ratio of Nb/(Ti+Al) is equal to 2.5-7.5.2015-08-06
20150218687CYLINDER LINER AND METHOD FOR PRODUCING SAME - The invention relates to a method for producing a thermally sprayed, thin-walled cylinder liner for insertion into a cylinder crankcase and to a cylinder liner produced with said method.2015-08-06
20150218688METHOD & STEEL COMPONENT - A method for heat treating a steel component, which comprises the steps of: (a) carburizing the steel component with a carbon potential above 1.0, (b) carburizing the steel component with a carbon potential above 0.6, (c) quenching the steep component, and (d) subjecting the steel component to a bainitic treatment.2015-08-06
20150218689COATED CUTTING INSERT - A cutting tool insert having a cemented carbide substrate and a coating including a layer of NbN, wherein the cemented carbide substrate includes 11-12.5 wt % cobalt, 0.2-1.2 wt % chromium, and 86.3-88.4 wt % wolfram carbide.2015-08-06
20150218690Vacuum Vapor Deposition Apparatus and Method - The present invention provides a vacuum vapor deposition apparatus, comprising a vacuum chamber, a vapor deposition source disposed in the vacuum chamber, and a positioning unit arranged above the vapor deposition source; wherein the vapor deposition source includes a heating container and a heating unit; wherein the heating container includes a material container, a steam vessel, and an output unit successively arranged from bottom to top; wherein a first partition disposed between the material container and the steam vessel defines a first vent; wherein a second partition disposed between the steam vessel and the output unit defines a second vent; and wherein the caliber of the first vent is larger than the second vent.2015-08-06
20150218691VACUUM VAPOR DEPOSITION APPARATUS - In a vacuum vapor deposition apparatus including a plurality of linear-shaped vaporization sources, equal-thickness surfaces are calculated for vaporization containers, respectively. Each of the equal-thickness surfaces indicates where a deposition amount of vapor of a vaporization material released from release holes in the corresponding vaporization container is the same per unit time. Then, the vaporization containers are placed in such a manner that contact points of the respective equal-thickness surfaces all coincide with each other on a deposition surface of a substrate, each of the contact points being where the corresponding equal-thickness surfaces come in contact with the surface of the substrate.2015-08-06
20150218692HIGH-TEMPERATURE PROCESSING FURNACE AND REINFORCEMENT FIBER JOINING METHOD - Arranged in the middle of an upper communication sleeve 2015-08-06
20150218693Chemical Vapour Infiltration Apparatus Having a High Loading Capacity - An installation for chemical vapor infiltration of porous preforms of three-dimensional shape extending mainly in a longitudinal direction, the installation comprising a reaction chamber of parallelepiped shape, the side walls of the reaction chamber including heater means and a plurality of stacks of loader devices arranged in the reaction chamber. Each loader device being in the form of an enclosure of parallelepiped shape provided with support elements for receiving porous preforms for infiltrating.2015-08-06
20150218694Substrate Including a Diamond Layer and a Composite Layer of Diamond and Silicon Carbide, and, Optionally, Silicon - A multilayer substrate includes a diamond layer CVD grown on a composite layer. The composite layer includes particles of diamond and silicon carbide and, optionally, silicon. A loading level (by volume) of diamond in the composite layer can be ≧5%; ≧20%; ≧40%; or ≧60%. The multilayer substrate can be used as an optical device; a detector for detecting radiation particles or electromagnetic waves; a device for cutting, drilling, machining, milling, lapping, polishing, coating, bonding, or brazing; a braking device; a seal; a heat conductor; an electromagnetic wave conductor; a chemically inert device for use in a corrosive environment, a strong oxidizing environment, or a strong reducing environment, at an elevated temperature, or under a cryogenic condition; or a device for polishing or planarization of other devices, wafers or films.2015-08-06
20150218695PROCESS AND METHOD FOR IN-SITU DRY CLEANING OF THIN FILM DEPOSITION REACTORS AND THIN FILM LAYERS - The invention relates to the use of thionyl chloride and related materials for dry etching of internal surfaces of metalorganic vapour phase epitaxy (MOVPE) reactors to remove deposits. The method is also useful for the dry etching of process substrates within such reactors for cleaning and processing of those substrates. The invention may be particularly adaptable to chemical vapor deposition reactors used in the manufacture of high brightness LED's based on III-V semiconductors such as GaN and related materials. Features of the process include thermal, UV, and plasma activated dry cleaning, and the use of etchant gases such as COCl2015-08-06
20150218696METHOD AND APPARATUS TO HELP PROMOTE CONTACT OF GAS WITH VAPORIZED MATERIAL - Vaporizable material is supported within a vessel to promote contact of an introduced gas with the vaporizable material, and produce a product gas including vaporized material. A heating element supplies heat to a wall of the vessel to heat vaporizable material disposed therein. The vessel may comprise an ampoule having a removable top. Multiple containers defining multiple material support surfaces may be stacked disposed within a vessel in thermal communication with the vessel. A tube may be disposed within the vessel and coupled to a gas inlet. Filters, flow meters, and level sensors may be further provided. Product gas resulting from contact of introduced gas with vaporized material may be delivered to atomic layer deposition (ALD) or similar process equipment. At least a portion of source material including a solid may be dissolved in a solvent, followed by removal of solvent to yield source material (e.g., a metal complex) disposed within the vaporizer.2015-08-06
20150218697INLINE DPS CHAMBER HARDWARE DESIGN TO ENABLE AXIS SYMMETRY FOR IMPROVED FLOW CONDUCTANCE AND UNIFORMITY - The present disclosure generally relates to apparatus and methods for symmetry in electrical field, gas flow and thermal distribution in a processing chamber to achieve process uniformity. Embodiment of the present disclosure includes a plasma processing chamber having a plasma source, a substrate support assembly and a vacuum pump aligned along the same central axis to create substantially symmetrical flow paths, electrical field, and thermal distribution in the plasma processing chamber resulting in improved process uniformity and reduced skew.2015-08-06
20150218698SPATIAL DEPOSITION OF MATERIAL USING SHORT-DISTANCE RECIPROCATING MOTIONS - Embodiments relate to performing deposition of material on a substrate by causing short-distance reciprocating motions of the substrate. A series of reactors for injecting material onto the substrate is arranged along the length of the substrate in a repeating manner. During each reciprocating motion, the susceptor moves a distance shorter than an entire length of the substrate. Portions of the substrate are injected with materials by a subset of reactors. Since the movement of the substrate is smaller, a linear deposition device including the susceptor may be made smaller.2015-08-06
20150218699HEAT EXCHANGER TYPE REACTION TUBE - A heat exchanger type reaction tube includes a first tube part that forms a first flow channel into which a feed gas flows and in which the feed gas moves down; a second tube part that forms a second flow channel which is connected to the first flow channel and in which the feed gas moves up and that has a granular catalyst carrying support medium charged therein; and a heating device that heats the first tube part and the second tube part. Then, the first flow channel and the second flow channel are adjacent to each other while being separated from each other by a partition wall, and the second flow channel is provided with a distributor which holds the catalyst carrying support medium and through which the feed gas passes.2015-08-06
20150218700CHAMBER COMPONENT WITH PROTECTIVE COATING SUITABLE FOR PROTECTION AGAINST FLOURINE PLASMA - Embodiments described herein relate to a protective coating that protects an underlying chamber component (i.e. the object upon which the coating is being deposited) from corrosion or deterioration within a corrosive environment.2015-08-06
20150218701TEMPERATURE CONTROLLED SHOWERHEAD FOR HIGH TEMPERATURE OPERATIONS - A temperature controlled showerhead assembly for chemical vapor deposition (CVD) chambers enhances heat dissipation to provide accurate temperature control of the showerhead face plate and maintain temperatures substantially lower than surrounding components. Heat dissipates by conduction through a showerhead stem and removed by the heat exchanger mounted outside of the vacuum environment. Heat is supplied by a heating element inserted into the steam of the showerhead.2015-08-06
20150218702ELECTROLESS PLATING METHOD, ELECTROLESS PLATING APPARATUS AND STORAGE MEDIUM - A multiple number of accurately-patterned metal layers can be formed on a substrate. On a substrate 2015-08-06
20150218703Method for manufacturing product with bright surface - A method of manufacturing a bright surface product comprises a step of performing electroless plating to form a first metal film on a base coat layer formed on a substrate, a step of performing electrolytic plating to form a second metal film thereon so that the bonding strength between each film of a multi-layered metal film comprising the first metal film and the second film is higher than the bonding strength between the base coat layer and the first metal layer, a step of integrally and discontinuously segmentalizing the multi-layered metal film with cracks to form an island-like metal film comprising a collection of fine multi-layered metal regions with island-like structures; and a step of forming a translucent top coat layer to cover the fine multi-layered metal regions of the island-like metal film and enter into the cracks to make contact with the base coat layer.2015-08-06
20150218704METHOD FOR APPLYING A COATING TO A SUBSTRATE - A method for applying a coating to a substrate surface is provided. The method involves cold spraying a coating material against the surface of the substrate at a first velocity. The first velocity is lower in magnitude than a critical velocity. The method also involves cold spraying the coating material against the surface of the substrate at a second velocity. The second velocity is greater in magnitude than the critical velocity. The critical velocity is a threshold velocity below which the coating material is substantially deflected by the surface of the substrate and above which the coating material substantially adheres to the surface of the substrate.2015-08-06
20150218705CONVERSION COATING COMPOSITION, SURFACE TREATED STEEL SHEET, AND METHOD FOR MANUFACTURING THE SAME - A conversion coating composition comprising 0.01 wt % to 0.2 wt % of phosphorous (P); 0.01 wt % to 0.2 wt % of magnesium (Mg); 0.005 wt % to 0.15 wt % of zirconium (Zr); 0.005 wt % to 0.15 wt % of titanium (Ti); 0.005 wt % to 0.15 wt % of vanadium (V); 0.05 wt % to 1 wt % of phenol resin; the balance of water and other unavoidable impurities is provided. A surface treated steel sheet comprising a base steel sheet; a zinc or zinc alloy plated layer formed on the base steel sheet; a blackening layer formed on the zinc or zinc alloy plated layer; and an organic and inorganic complex conversion coating layer formed on the blackening layer, wherein the organic and inorganic complex conversion coating layer may satisfy the weight ratio of P:Mg:Zr:Ti:V=1:0.045 to 2:0.035 to 1.5:0.035 to 1.3:0.035 to 1.5 (based on the weight of P) is also provided. A method for manufacturing a steel sheet treated with the conversion coating composition is also provided.2015-08-06
20150218706PRODUCTION METHOD OF GALVANNEALED STEEL SHEET HAVING EXCELLENT FORMABILITY AND EXFOLIATION RESISTANCE AFTER ADHESION - The production method of the galvannealed steel sheet includes: performing a hot dip galvanization on a steel sheet; performing an alloying and forming a galvannealed layer; performing a skin pass rolling at an elongation ratio of 0.3% or more; applying a treatment liquid on a surface of the galvannealed layer using a roll coater, and allowing the treatment liquid to react with the surface immediately after the application to form a mixed layer; in the forming the mixed layer: a first applied part is formed in the mixed layer using the protrusions of the roll coater; and a second applied part is formed in the mixed layer using the recesses of the roll coater; the second applied part having an attached amount of P of 20 mg/m2015-08-06
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