| Entries |
| Document | Title | Date |
|---|
| 20080221550 | RAPID EXCHANGE INFUSION CATHETER - An infusion catheter and method, with an elongated shaft having a guidewire lumen which has a proximal section and a common distal section extending to a distal port at a distal end of the shaft, and an infusion lumen which is in fluid communication with the distal port of the guidewire lumen and which joins the common distal section of the guidewire lumen at a location distal to the guidewire proximal port. A restricted passage from the infusion lumen to the common distal section of the guidewire lumen has a smaller transverse dimension than the guidewire lumen and a guidewire slidably disposed in the guidewire lumen. | 09-11-2008 |
| 20080221551 | ACUTE KIDNEY INJURY TREATMENT SYSTEMS AND METHODS - Systems and methods for the clinical treatment of individuals susceptible to or suffering from acute kidney injury are provided. Drugs, biologics, or other therapies or treatments are administered by fluid agent delivery directly to the kidneys via their arterial blood supply. Bifurcated renal artery infusion catheter devices and methods can treat kidney injury in patients with locally-delivered drugs, biologics, and other agents, so as to increase the ability of the kidneys to excrete nitrogenous waste products from the blood, and prevent or ameliorate azotemia. | 09-11-2008 |
| 20080234657 | METHODS FOR CONTRIBUTING TO CARDIOVASCULAR TREATMENTS - Disclosed herein are methods that can contribute to cardiovascular treatments. The methods are designed to provide bioactive materials to the first proximal third of coronary arteries, the portion of these arteries most likely requiring treatment. | 09-25-2008 |
| 20080234658 | Device and Methods for Controlling Blood Perfusion Pressure Using a Retrograde Cannula - Devices and methods are disclosed for the control of blood perfusion pressure within a blood vessel that undergoes arterialization. A cannula is introduced that contains a stenosis that either resorbs or is removed in time, allowing a gradual increase in blood pressure between two blood passages connected at either ends of the cannula. Particular emphasis has been made with the use of the cannula for the vessels in the heart. | 09-25-2008 |
| 20080269719 | IMPLANTABLE MEDICAL DEVICE DELIVERY SYSTEM WITH A FRANGIBLE PORTION AND METHODS OF MAKING AND USING THE SAME - An implantable medical device delivery system is provided with a carrier member having a proximal portion, a distal portion, and a frangible portion intermediate the proximal and distal portions. The frangible portion includes at least one notch providing a break hinge. A locking member is fixedly secured to the proximal portion of the carrier member and is releasably connected to an implantable medical device at or adjacent to the distal portion of the carrier member. In use, the implantable medical device is positioned generally adjacent to a target location of a body vessel and the frangible portion is broken about the break hinge. The proximal portion of the carrier member is then moved away from the distal portion to retract the locking member, thereby deploying the implantable medical device. | 10-30-2008 |
| 20080269720 | Cardiac repair, resizing and reshaping using the venous system of the heart - Structurally supportive material is implanted or injected into cardiac veins as discrete masses at various sites in the cardiac venous system to reinforce the myocardium for the purpose of preventing, moderating, stopping or reversing negative cardiac remodeling due to various adverse cardiac conditions, both acute and chronic, or for the purpose of treating localize anomalies of the heart, or for both purposes. The sites may be arranged in a pattern about one or more chambers of the heart such that the masses cooperatively reduce stress in the chamber wall and reduce chamber size. Some patterns also cause a beneficial global reshaping of the chamber. These changes occur quickly and are sustainable, and have a rapid and sustainable therapeutic effect on cardiac function. Patterns of distribution of discrete masses in the heart for global resizing and reshaping may also be used as is or augmented by supplemental patterns to treat localized conditions such as myocardial infarctions and overt aneurysm of the ventricular wall as typically forms in response to large transmural myocardial infarctions. These techniques may also be used to treat localized conditions that may not yet have progressed to cardiomyopathy. | 10-30-2008 |
| 20080287911 | CATHETER WITH LAMINAR FLOW DRUG DELIVERY PROPERTIES - Catheters with laminar flow bioactive agent delivery properties and methods of using for treating or preventing vascular disease are disclosed. | 11-20-2008 |
| 20080294144 | Touch Sensing Catheter - A touch sensing catheter having a strain sensor assembly that may resolve the magnitude and direction of a force exerted on a distal extremity of the catheter, the strain sensor assembly being substantially insensitive to bulk temperature changes. A deformable structure having a plurality of optical fibers associated therewith that are strained by the imposition of a contact force transferred thereto. The optical fibers cooperate with the deformable structure to effect variable gap interferometers, such as Fabry-Perot resonators, that vary in operative length when a force is exerted on the deformable structure. The strain sensor assembly is rendered insensitive to bulk temperature changes by matching the coefficient of thermal expansion of the deformable body with that of the optical fibers. The strain sensor assembly may also be configured to mitigate the effects of thermal gradients using various thermal isolation techniques. | 11-27-2008 |
| 20080312636 | Systems and Methods for Needle Access to an Intervertebral Disc - A catheter with a balloon anchor may be sized to fit through an inner needle and introduced into the patient through the needle. The inner needle may comprise an atraumatic needle with a side port and/or a blunt tip. The catheter may include a radiopaque coil disposed over the distal portion of the catheter body to assist with catheter placement when viewed with fluoroscopy and/or x-ray. The distal portion of the catheter can be very flexible. A balloon inflation tube may terminate proximal to a proximal end of the expandable balloon anchor such that the distal portion of catheter can be flexible. This termination of the inflation tube may also position the inflation tube away from the annulus and nerve roots, so as to avoid irritation of the annulus and rubbing of the nerve roots that may potentially obscure FAD test results. | 12-18-2008 |
| 20090018525 | Tapered catheter devices - Catheters, catheter systems, and methods of using catheters to deliver therapy are disclosed. Advantages include increased torqueability and control with catheters, having a soft distal tip. Catheter systems including a sheath and catheter are disclosed wherein the catheter fits the sheath with a dilator-like fit. | 01-15-2009 |
| 20090018526 | Devices and Methods for Perfusing an Organ - The present invention provides devices and methods for use in the perfusion of organs and anatomical regions. In one aspect the present method provides a percutaneously deliverable device for supporting a vessel in a human or animal subject including means for supporting the vessel during delivery of a fluid thereto or collection of a fluid therefrom. In another aspect the invention provides a method for delivery or collection of a fluid to or from an organ or anatomical region in a human or animal subject, the method including the step of supporting a vessel associated with the organ or anatomical region. The devices and methods may be used to deliver, remove or recirculate a therapeutic agent to an organ or anatomical region. | 01-15-2009 |
| 20090024106 | Method and apparatus for maintaining access - An apparatus and a method for sealing a puncture in a tubular tissue structure or the wall of a body cavity are provided. | 01-22-2009 |
| 20090048576 | Managing Cross-contamination in Blood Samples Withdrawn from a Multilumen Catheter - The present invention comprises methods and apparatuses that can provide accurate measurement of glucose or other analytes from a multilumen catheter in the presence of infusion of substances, including glucose. Examples of “multilumen catheters” include central venous catheters having multiple lumens, midline catheters having multiple lumens, multiple catheters configured or emplaced such that their lumens are in proximity to each other, and, in the case of indwelling analyte sensors, a catheter with a lumen for infusion and an indwelling sensor spaced apart from the infusion lumen. For blood withdrawal, anti-cross contamination controls can prevent the entrainment of blood which might be contaminated with feeding fluids or medications that are administered through other lumens within the catheter and in proximity of the blood sampling port. Cross contamination can occur under various situations, and is known to occur when the patient is connected to a ventilator. The ventilator cyclically raises the intra-thoracic pressure and diminishes blood flow rate in the central veins returning to the heart. The diminished flow can increase the chances for cross-contamination when additional lumens are introducing fluids during a draw sample. | 02-19-2009 |
| 20090076480 | Active Ingredient-Containing Silicone Elastomers - The invention relates to compositions comprising silicone elastomers and antimicrobially active substances in homogeneous distribution, a process for their production and their use in medical articles. | 03-19-2009 |
| 20090088723 | APPARATUS AND METHODS FOR TREATING PSEUDOANEURYSMS - Apparatus and methods are provided for treating pseudoaneurysms using freeze-dried hydrogel particles that expand and/or absorb fluid within a pseudoaneurysm. An apparatus includes an elongate tubular member including a proximal end, a distal end sized for introduction through tissue into a pseudoaneurysm or other body cavity, and a lumen communicating with an outlet on the distal end. The particles are provided within the lumen and dischargeable through the outlet, e.g., using a plunger or other actuator. The apparatus may include one or more of a bled-back channel, flow sensor, pressure sensor, and markers for monitoring the distal end during introduction into the pseudoaneurysm. | 04-02-2009 |
| 20090088724 | Multiple Stage Fluid Delivery Device and Method of Use - Multiple stage fluid delivery devices are provided for dispensing a first fluid at a first flow rate and thereafter dispensing a second fluid at a second flow rate which is substantially lower than the first flow rate. The device may be used to inject a fluid into a catheter to flush the catheter and to thereafter slowly deliver fluid into the catheter to maintain patency of the catheter. | 04-02-2009 |
| 20090118700 | METHOD FOR TREATING CORONARY VESSELS - A method is provided including introducing a delivery device through a vessel wall to a treatment site within one of a peri-adventitial space or a pericardium adjacent a coronary blood vessel and delivering a treatment agent through the delivery device. The treatment agent is delivered through the delivery device according to conditions that hydraulically dissect tissue planes within the peri-adventitial space. A kit is provided including a delivery device having a needle to be advanced through one of an epicardium of a heart and a wall of a coronary blood vessel into a peri-adventitial space and a treatment agent comprising particles having an average diameter on the order of 15 microns or more to be delivered through the delivery device into the peri-adventitial space. | 05-07-2009 |
| 20090247986 | Flapper Valve with Membrane Bypass for Power PICC - A bypass for power injection includes (a) a housing defining a lumen extending from a proximal end to a distal end coupled to a catheter; (b) a membrane valve mounted within the lumen, the membrane valve having an opening extending therethrough sized to tightly receive therethrough and seal around a power injection device; and (c) a flapper valve extending across the lumen distally of the membrane valve. The flapper valve includes a flap biased toward a closed position in which the lumen is sealed. The flap is rotatable away from the closed position when contacted by a power injection device to permit the device to extend therethrough. | 10-01-2009 |
| 20090254062 | Infusion catheters with slit valves and of simplified construction - The present invention relates to catheters to deliver a fluid to a patient. A catheter of the invention comprises a plurality of slits through which the fluid is delivered to the patent. A catheter of the invention is designed in a simple manner to lower costs and provide a reliable means to deliver fluids to a patient. The invention further comprises methods for making a catheter of the invention and methods of delivering a fluid to a patient with a catheter of the invention. | 10-08-2009 |
| 20090264858 | Catheter Having a Detachable Tip - A catheter is disclosed that has a detachable tip for delivery of a therapeutic substance to a chronic total occlusion (CTO) within a body vessel. The tip is made from a biodegradable material and includes an active agent dispersed therethrough. The detachable tip pierces into the calcified lesion, detaches from the catheter, and remains embedded within the lesion as the tip degrades, thereby releasing the active agent. The active agent is a therapeutic substance effective to treat of a CTO. The active agent may be a drug, an enzyme, bacteria, or a parasite that degrades or softens the calcified lesion. | 10-22-2009 |
| 20090275918 | PANCREATIC DELIVERY CATHETER - Pancreatic delivery catheters which facilitate direct intravascular access to the pancreas are described herein. A catheter which is configured particularly for pancreatic access may generally comprise a distal section which defines three curves each extending in an alternating pattern and a proximal section with an additional curve in an opposing direction. A primary curve defined along the distal section may define an acute angle with respect to a secondary curve and which also curves in an opposite direction. The secondary curve may define an acute angle with respect to both the primary curve and a tertiary curve which is proximal of the secondary curve. Similarly, a tertiary curve may extend in an opposite direction from the secondary curve. A quaternary curve along the proximal section may extend in an opposite direction from the tertiary curve. | 11-05-2009 |
| 20090318890 | Portable Medical Foam Apparatus - An apparatus for producing medical foam having a foam generation unit including a fluid reservoir, a fluid delivery line and a foam generation tip; and a compressed gas unit including at least one container of compressed gas, a source of electric power, and a gas regulator valve. | 12-24-2009 |
| 20100004627 | NEEDLE CATHETER WITH AN ANGLED DISTAL TIP LUMEN - A needle catheter configured for injecting an agent into a wall of a patient's body cavity, which directs a needle from the distal tip of the catheter into the wall of the body cavity at an angle relative to the axis of the shaft. The resulting angled injection pathway improves the retention of the agent in the body cavity wall, while keeping a distal section of the catheter substantially perpendicular to the body cavity wall for optimal push against the tissue at the injection site. | 01-07-2010 |
| 20100010469 | PRE-FORMED DELIVERY CATHETERS - A delivery catheter includes a pre-formed and resilient heart-wrapping segment. The segment may have a relaxed span that allows the segment to wrap around a left side of a heart from an anterior epicardial surface to a posterior epicardial surface, when the catheter is advanced along the epicardial surface, having been inserted from a sub-xiphoid access site. | 01-14-2010 |
| 20100016831 | Catheter Having an Oblong Slit - A catheter ( | 01-21-2010 |
| 20100016832 | SPIRALLY CONFORMABLE INFUSION CATHETER - An infusion catheter includes a catheter body having a proximal end, a distal end, and two or more lumens extending therethrough. The infusion catheter also includes an infusion tube having a proximal end, a distal end, and one or more ports disposed therethrough. The first lumen of the catheter body is in fluid communication with the lumen of the infusion tube. A central member has a distal end connected to the distal end of the infusion tube, a proximal end, and a proximal portion slidably received in the second lumen of the catheter body. The infusion tube is disposed relative to the central member such that axial advancement of the central member relative to the catheter body radially collapses the infusion tube over the central member and axial retraction of the central member relative to the catheter body radially expands the infusion tube about the central member. | 01-21-2010 |
| 20100049165 | DETACHABLE TIP MICROCATHETER - A microcatheter for delivering embolic agent to a vascular site is provided. The microcatheter has a biocompatible or biocompatible and biodegradable tip which can be detachably engaged to the microcatheter body by a thermoplastic sleeve. Once the embolic agent is delivered to the desired vascular site, the tip of the microcatheter is often entrapped within the mass of the liquid embolic fluid. Using the microcatheter, the clinician can retract the microcatheter at a predetermined retraction force thereby disengaging the tip from the microcatheter body allowing for easier removal of the microcatheter. | 02-25-2010 |
| 20100100071 | SYSTEM AND METHOD FOR CONTROLLING FLUID PRESSURE DURING A MEDICAL INFUSION - A system for controlling an infusion of fluid into living tissue includes a catheter shaped to be introduced within living tissue and operable to deliver a fluid to a location within the living tissue, a fluid infusion pump mechanically coupled to the catheter and operable to pump fluid through the catheter and, thereby, into the location, the fluid infusion pump having at least two fluid pumping states, a fluid pressure monitor fluidically coupled to the catheter and operable to measure a pressure of the fluid within the catheter, and a processor communicatively coupled to the fluid infusion pump and the fluid pressure monitor, the processor operable to select between the at least two fluid pumping states based upon the measured pressure of the fluid within the catheter. | 04-22-2010 |
| 20100106135 | ANGIOCATHETER AND METHOD OF OPERATING THE SAME - An improved angiocatheter device for introducing intravenous fluids or drugs into the lumen of a patient through a sheath. At the point of the procedure where a needle needs to be removed but the sheath is to remain implanted, a spring in the needle portion of the device is expanded thereby retracting the needle and allowing the operator to remove the needle from the sheath and an introducer hub. This feature allows for quick insertion and removal from the patient without the necessity of sliding or otherwise removing the needle from the sheath in a multiple step process. In this manner, the catheter or lead can implanted quickly and safely while also protecting the operator from accidental exposure to the patient's blood and eliminating the need to apply positive pressure to the lumen while the needle is being removed. | 04-29-2010 |
| 20100114062 | Methods and devices for providing oxygenated blood distal to an obstruction - The catheter is positioned within an obstruction so that the distal end is positioned distal to the obstruction and proximal openings are positioned proximal to the obstruction. Blood enters the proximal openings and passes through the lumen to the distal end to perfuse blood distal to the obstruction. | 05-06-2010 |
| 20100114063 | CATHETER INJECTION MONITORING DEVICE - A catheter is provided that has at least one lumen which extends from a proximal end of the catheter to a distal end of the catheter. The catheter also has a catheter hub that has a body with a proximal end, a distal end, an exterior surface, and defining an interior cavity. The exterior surface of the body further defines at least one opening. At least one opening is defined therein the proximal end, and at least one opening is defined therein the distal end. The catheter also has a means for measuring and displaying the number of times that the catheter is injected with an infusate at a pre-determined pressure. | 05-06-2010 |
| 20100114064 | MITIGATION OF CONTRAST-INDUCED NEPHROPATHY - A system, includes a pressurizing mechanism to pressurize a fluid including a contrast enhancement agent for delivery to a patient; and a control system in operative connection with the pressurizing mechanism. The control system includes a system to adjust control of fluid injection based upon a measurement of renal function of the patient. | 05-06-2010 |
| 20100137834 | SYRINGE ASSEMBLY - A syringe assembly comprises a syringe barrel having an elongated body defining a chamber for retaining fluid, an open proximal end, a distal end and a frusto-conically shaped tip extending from the distal end and having a passageway therethrough in fluid communication with the chamber. The chamber has an inside diameter of at least 13.5 mm. A stopper is in fluid-tight engagement inside the barrel. An elongated plunger rod extends proximally from the stopper through the open proximal end of the barrel. A flange is positioned at the proximal end of the plunger rod. The flange is shaped and positioned to limit the distal motion of the plunger rod in the barrel by contacting the proximal end of the barrel. A tip cap is releasably connected to the tip for sealing the passageway and the chamber contains injectable liquid. | 06-03-2010 |
| 20100137835 | DEPLOYMENT SYSTEM FOR MYOCARDIAL CELLULAR MATERIAL - A catheter-based deployment system for deploying cellular material ( | 06-03-2010 |
| 20100145306 | Various Catheter Devices for Myocardial Injections or Other Uses - A catheter device comprising a proboscis shaft and a proboscis disposed within the proboscis shaft. In certain embodiments, the catheter device further comprises an elongate tubular member, wherein the proboscis shaft is disposed within the elongate tubular member. In certain embodiments, the catheter device comprises a tissue surface engagement structure, which has a first configuration and a second configuration. In the second configuration, the tissue surface engagement structure presents a larger transverse profile in comparison to the first configuration. The tissue surface engagement structure may have any of various designs, including an expandable assembly and a hinged assembly. In certain embodiments, a deformable cushion is positioned at the distal end of the proboscis shaft. The deformable cushion comprises a pocket that is filled with a reshapeable material. In certain embodiments, the proboscis shaft comprises a longitudinally compressible portion. | 06-10-2010 |
| 20100160896 | Blood Flow Bypass Catheters and Methods for the Delivery of Medium to the Vasculature and Body Ducts - A catheterization device that may be designed by use of an adaptive genetic algorithm computational fluid dynamics approach, as well as other Global Optimization methods that may include simulated annealing, multistart and interval methods, continuous branch and bound methods, evolutionary algorithms, and tabu search and scatter search methods, as well as other available Global Optimization methods that is able to maximize/optimize the dwell time of an infused agent in the vicinity of a vascular lesion. The device may have an internal by-pass channel that allows the blood upstream of the lesion to continue its pulsatile flow through the vessel in the part of it occluded by the lesion, while simultaneously allowing the disbursement and maximal dwell time of an antithrombolytic or other diagnostic or therapeutic agent needed to treat the lesion. Different embodiments of the catheterization device are disclosed and indications for the use of these devices in the treatment of vascular diseases are discussed. | 06-24-2010 |
| 20100160897 | Apparatus and Methods for Containing and Delivering Therapeutic Agents - The present embodiments provide apparatus and methods suitable for containing and delivering a therapeutic agent to a target site. The apparatus generally comprises at least one container for holding a therapeutic agent, and a pressure source for facilitating delivery of the therapeutic agent. In one embodiment, the pressure source may be placed in selective fluid communication with a proximal region of the container and fluid from the pressure source may flow through at least a portion of the container to urge the therapeutic agent through the container towards the target site. In an alternative embodiment, the pressure source may be selectively in fluid communication with either a first hollow tube and the container so that therapeutic agent is urged into a catheter, or with a second hollow tube and a catheter so that a fluid from the pressure source bypasses the container and enters the catheter. | 06-24-2010 |
| 20100160898 | METHOD AND APPARATUS FOR STORAGE AND/OR INTRODUCTION OF IMPLANT FOR HOLLOW ANATOMICAL STRUCTURE - Apparatus for advancing a vascular implant into a blood vessel. The apparatus comprises a first elongate member, the first elongate member having sufficient column strength to function as a pusher member; and a second elongate member, the second elongate member being thinner than the first elongate member and extending to a distal end located at a first point which is at or near a distal end of the first elongate member. The elongate members form an implant retaining portion while the distal end of the second elongate member is located at the first point. The implant retaining portion is located proximal of the first point. The implant retaining portion comprises a space located between the elongate members and configured for receiving an implant portion, with the first elongate member on one side of the space and the second elongate member on another side. The implant retaining portion further comprises a proximal side and a distal side which further circumscribe the space. The proximal and distal sides are effective to prevent an implant received in the retaining portion from moving out of engagement with the retaining portion as the first elongate member is moved distally and proximally. The implant retaining portion is removable by withdrawing the second elongate member in a proximal direction with respect to the first elongate member, thereby moving the distal end of the elongate member proximally beyond the former location of the implant retaining portion. Associated methods, and other apparatus and methods, are also disclosed. | 06-24-2010 |
| 20100168713 | CATHETER FOR INTRODUCTION OF MEDICATIONS TO THE TISSUES OF A HEART OR OTHER ORGAN - A positionable, direct-injection catheter that can access a specific region of the heart or other organ. The catheter is provided with one or two needle shafts, which may be located within respective sheaths that extend axially along the interior of the lumen of a main catheter shaft. Each needle shaft carries, at a distal end thereof a penetrable element or “needle” that is normally retracted within the distal tip of the main shaft during travel to the target organ, but is subsequently deployed by action of a handle-mounted trigger mechanism to extend the needles into the organ's wall. Each extended needle is curved to relative to the shaft's axis to enter the organ wall in a flattened trajectory that both reduces the chance of puncture through the wall and anchors the needles into the wall during injection (for reduced chance of pullout under pressure). A plurality of apertures which provide for more complete agent delivery rapidly, while maintaining a low delivery velocity to effect treatment delivery in as short a period of time as possible without the problems caused by high velocity delivery. The needles are typically arranged to exit the tip at contralateral orientations relative to each other. | 07-01-2010 |
| 20100185179 | NEEDLED CANNULA WITH FILTER DEVICE - An apparatus may include a cannula. The cannula may be operable to be percutaneously advanced through a blood vessel. The cannula may have a proximal end and a distal end. At least one needle may be coupled to the distal end of the cannula. A filter device may be coupled at a position proximal to the at least one needle. The filter device may have a distal portion that is operable to have a first diameter under a first condition and a second, different diameter under a second condition. Methods of using such an apparatus are also disclosed. | 07-22-2010 |
| 20100191219 | Bacteriostatic Catheter Lock Containing Glycerol - A catheter lock composition for preventing bacterial infection having an effective amount of glycerol and sodium chloride solution. The effective amount of glycerol is between about 35-60% and sodium chloride is in a concentration range between 0.5-0.9%. The composition further includes an anticoagulant and/or an antimicrobial agent. | 07-29-2010 |
| 20100217232 | BYPASS VALVE - An intravenous fluid administration apparatus may include a proximal conduit having a spiked first end for attaching to a reservoir of fluid and a second end, a distal conduit, an intermediate conduit network providing fluid communication from the proximal conduit's second end to the distal conduit and including first and second constituent conduits that provide parallel paths from the proximal conduit to the distal conduit, a flow regulator so engaged with the first constituent conduit as to enable control of fluid flow therethrough, and a pressure-responsive valve so interposed in the second constituent conduit as to permit flow from the proximal conduit to the distal conduit through the second constituent conduit when a fluid pressure difference across the valve exceeds a threshold and to prevent such flow when the difference does not exceed the threshold. | 08-26-2010 |
| 20100286657 | HIGH-FLOW TAPERED PERIPHERAL IV CATHETER WITH SIDE OUTLETS - A high-volume peripheral intravenous (IV) catheter and method includes an elongate stylet removably disposed in the lumen of an elongate catheter with the stylet having a beveled distal end forming a piercing tip that protrudes from the outlet port of the catheter. The catheter has a proximal cylindrical shape from the inlet port transitioning at a transition to an inner lumen conical taper terminating at the outlet port, and having a larger internal diameter at the inlet port and a tapering smaller internal diameter between the transition and the outlet port. A plurality of side outlet ports is formed laterally through the catheter in the inner lumen conical taper. A cross-sectional area of the outlet port and the side outlet ports together is equal or greater than a cross-sectional area of the inlet port. | 11-11-2010 |
| 20100305547 | Method of use of fibroblast growth factor, vascular endothelial growth factor and related proteins in the treatment of acute and chronic heart disease - Disclosed herein is a rational, multi-tier approach to the administration of growth factor proteins in the treatment of heart disease. Also disclosed is a method to evaluate the effectiveness of the administration of growth factor proteins comprising the clinical assay of CPK-MB levels in a patient undergoing treatment with growth factor proteins. In addition, there is disclosed a method for treatment of heart disease comprising administration of a therapeutically effective amount of a growth factor protein by oral inhalation therapy. | 12-02-2010 |
| 20100318061 | Catheter - The invention relates to rigid surgical devices formed from rigid ceramics such as zirconium dioxide. In particular, the invention relates to a neurosurgical catheter formed from extruded zirconium dioxide. The invention also relates to an advancement means for advancing or retracting such a device along an axis of insertion into a patient. | 12-16-2010 |
| 20100324533 | CATHETER SYSTEM AND METHOD FOR DELIVERY OF THERAPEUTIC COMPOUNDS TO CARDIAC TISSUE - This is a method and an apparatus for the treatment or introduction of contrast fluids into tissue, particularly cardiac tissue. The apparatus includes a catheter having an elongated flexible body and a tissue infusion apparatus including a hollow infusion needle configured to secure the needle into the tissue when the needle is at least partially inserted into the tissue to help prevent inadvertent removal of the needle from the tissue. This permits the selected treatment or contrast fluid to be confined to a specific site. The catheter may also include a visualization assembly including a transducer at the distal end of the body. | 12-23-2010 |
| 20110071495 | SHAPE MEMORY EMBOLIC PARTICLES HAVING A HIGH PACKING FRACTION - An embolization system having a high packing fraction of embolic particles for use in occluding the flow of body fluid through a body vessel and a method for using such an embolization system are described. The embolic particles, which are made from a shape memory material, exhibit both a collapsed state and an expanded state. The embolic particles exhibit at least a bimodal particle diameter distribution in the collapsed state and expanded state with a particle packing fraction of at least about 0.85. The mixture of embolic particles is delivered into the body vessel in the collapsed state. The particle packing fraction of the mixture in its expanded state causes the occlusion of the flow of body fluid through the body vessel. | 03-24-2011 |
| 20110071496 | BIOLOGICS INFUSION SYSTEM - A system for moving particles suspended in a first fluid, and for infusing them into the stream of a second fluid, includes a catheter with a multi-lumen distal tip. The tip is formed with a plurality of parallel lumens, wherein each lumen has a predetermined diameter. Importantly, the diameter of each lumen is dimensioned to sequentially receive particles therethrough, to prevent the particles from flocculating before they enter the stream of the second fluid. A valve, affixed to the outside of the catheter, can be provided to regulate flow of the second fluid and thereby facilitate entry of the particles into the stream of the second fluid. | 03-24-2011 |
| 20110125131 | ENDOLUMINAL DELIVERY OF ANESTHESIA - Described herein are methods and devices for selectively applying fluids (particularly anesthetics) to a target tissue from within a blood vessel while minimizing the amount of fluid applied to non-target tissue. The injection catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter before extending the injector. The methods of selectively applying anesthetic to a target structure generally include the steps of inserting an injection catheter into a body vessel, positioning the injection catheter within the body vessel near the target structure, anchoring the injection catheter before extending a directional injector from the injection catheter, and applying anesthetic from the injection catheter to the target structure. | 05-26-2011 |
| 20110130744 | DEVICES, SYSTEMS, AND METHODS FOR ACCESSING THE EPICARDIAL SURFACE OF THE HEART - Devices, systems, and methods for accessing the internal and external tissues of the heart are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for localized delivery of leads to the heart tissue. In addition, various disclosed embodiments provide devices, systems, and methods for closing a hole in cardiac tissue. | 06-02-2011 |
| 20110144620 | INTRAVASCULAR CATHETER WITH POSITIONING MARKERS AND METHOD OF PLACEMENT - An intravascular catheter may include a distal end for insertion and a proximal end. The distal end for insertion may terminate with a tip. It may define at least two openings, of which one is proximal-most in the distal end. The distal tip may include a first radiopaque marker that is discretely positioned at the proximal-most opening and radiographically distinguishes the proximal-most opening from the rest of the distal end. The distal tip may also include a second radiopaque marker that marks the tip. | 06-16-2011 |
| 20110152835 | METHODS AND COMPOSITIONS FOR THE REPAIR AND/OR REGENERATION OF DAMAGED MYOCARDIUM - Methods, compositions, and kits for repairing damaged myocardium and/or myocardial cells including the administration cytokines are disclosed and claimed. Methods and compositions for the development of large arteries and vessels are also disclosed and claimed. The present application also discloses and claims methods and media for the growth, expansion, and activation of human cardiac stem cells. | 06-23-2011 |
| 20110208159 | Catheter Locking Composition - The present invention relates to locking compositions, kits containing the locking compositions and methods for maintaining the patency of vascular access devices or intravascular delivery devices employing the locking compositions. The locking compositions contain water, an anticoagulant and a viscosity agent and are free of heparin and alcohol. | 08-25-2011 |
| 20110218517 | IN VIVO CHEMICAL STABILIZATION OF VULNERABLE PLAQUE - Procedures for the stabilization of vulnerable plaque can comprise identification of the vulnerable plaque and the delivery of a stabilization composition to the location of the vulnerable plaque. For example, the stabilization composition can be delivered to an isolated portion of the vessel with the vulnerable plaque and/or alternatively or additionally using a profusion balloon that delivers the stabilization composition at the vessel wall near the vulnerable plaque. Suitable stabilization compositions can comprise a collagen crosslinking agent, an elastin stabilization agent, VEGF or a combination thereof. Vascular endothelial growth factor (VEGF) can be used to encourage endothelialization of the vessel wall near the vulnerable plaque. | 09-08-2011 |
| 20110230858 | METHODS AND DEVICES FOR PROVIDING OXYGENATED BLOOD DISTAL TO AN OBSTRUCTION - The catheter is positioned within an obstruction so that the distal end is positioned distal to the obstruction and proximal openings are positioned proximal to the obstruction. Blood enters the proximal openings and passes through the lumen to the distal end to perfuse blood distal to the obstruction. | 09-22-2011 |
| 20110238039 | Method and Apparatus for Improving Delivery of an Agent to a Kidney - Methods for more uniformly delivering drugs or other treatment agents locally to the vasculature of a mammal are disclosed. These methods use one or more strategies to facilitate rapid mixing with the blood flowing past a device or otherwise improve the uniformity of drug delivery. Some of these strategies employ medical devices with diffusion members. | 09-29-2011 |
| 20110251588 | Infusion Mechanism And Method - An infusion mechanism for treating an intraluminal site in a patient includes an infusion catheter having an elongate body with a proximal body end defining at least one fluid supply orifice, and a distal body end. The elongate body defines a high head loss lumen in fluid communication with a first set of side ports defining a proximal infusion zone. The elongate body further defines a low head loss lumen in fluid communication with a second set of side ports defining a distal infusion zone. | 10-13-2011 |
| 20110251589 | Catheter With Distensible and Frangible Cap - A catheter for delivering a medical implant in a patient's vasculature includes an elongate catheter having a distensible and frangible cap mounted across the open distal end thereof. The cap is distendable by pressure within the catheter to provide a bumper tip for guiding the catheter through a patient's vasculature. At the desired site for deploying the medical implant, the cap is ruptured to permit the implant to be advanced through the distal opening. Methods of using the catheter are also disclosed. | 10-13-2011 |
| 20110264073 | DEVICE AND METHOD FOR CONTROLLING INJECTION OF LIQUID EMBOLIC COMPOSITION - A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream. | 10-27-2011 |
| 20120035585 | TAPERED VENOUS ACCESS INTRODUCER - A system and method for vessel catheterization is provided, having an introducer sheath and a catheter. The introducer sheath can include a handle and a sheath body extending from the handle. An access lumen is provided in the introducer sheath, and can include a tapered portion that is sized to receive a tapered outer surface of the catheter. The catheter may be a central venous catheter, such as a peripherally inserted central catheter, including a hub, a catheter body with at least one lumen extending distally from the hub, and at least one tube extending proximally from the hub. The introducer sheath is preferably a splittable sheath. The catheter can be inserted into the access lumen, and translated until confronting surfaces of the tapered outer surface of the catheter body and the tapered portion of the introducer sheath contact one another. This arrangement can inhibit buckling and/or kinking of the catheter during insertion, and improve initial catheter tip positioning. | 02-09-2012 |
| 20120035586 | Infusion Catheter And Method - An infusion catheter includes an elongate catheter body having a proximal body component and a distal body component. The distal body component includes a distal body outer surface and a distal body inner surface defining an infusion lumen. The distal body component further includes a skeleton, and a porous infusion control textile contacting the skeleton and extending circumferentially about a longitudinal axis of the catheter and defining a fluid emission profile thereof. The porous infusion control textile further includes a fiber network having a higher density space filling configuration at a proximal textile end and a lower density space filling configuration at a distal textile end, and defining a pressure sensitive flow rate property and a pressure insensitive flow distribution property of the fluid emission profile. | 02-09-2012 |
| 20120035587 | METHODS AND SYSTEMS FOR PROVIDING THERAPIES INTO THE PERICARDIAL SPACE - Methods and systems for transvenously accessing the pericardial space via the vascular system and atrial wall, particularly through the superior vena cava and right atrial wall, to deliver a pharmacologic agent, particularly a NO-donor drug, to the heart are disclosed. A proximal connector of an infusion catheter is coupled to an infusion pump, and a distal catheter segment having a distal infusion catheter lumen end opening is disposed in the pericardial space. The implantable infusion pump is operable in conjunction with an implantable ischemia monitor to monitor the ischemic state and trigger delivery or regulate the periodic delivery of the pharmacologic agent to optimally treat ischemia. The patient may operate a patient activator that the patient when feeling ischemia symptoms to transmit a signal that is received by the implantable infusion pump and triggers delivery of a bolus and/or continuous infusion. | 02-09-2012 |
| 20120059355 | METHODS OF MODIFYING MYOCARDIAL INFARCTION EXPANSION - A reinforcement region is formed within the myocardium by introducing a delivery device through a vessel wall to a treatment site within a myocardium. A biomaterial is then delivered to the treatment site as the delivery device is withdrawn from the treatment site to form the reinforcement regions. Formation of the reinforcement region may further include introducing a delivery device through a vessel wall to a region within a myocardium such that the delivery device is positioned within the myocardium substantially parallel to a wall of the myocardium. A biomaterial may be delivered into a space formed within the region by the delivery device. The reinforcement region may be formed around an infarct tissue region of a myocardium to reinforce the damaged tissue. | 03-08-2012 |
| 20120116350 | TRANSLATION DILATOR AND STAND ALONE VASCULAR GUIDE CATHETER - Systems and methods for delivering implantable devices, catheters, or substances in or near and/or restoring flow through body lumens, such as blood vessel lumens are described. A catheter having a proximal portion of a first diameter and a distal portion of a second diameter (smaller than the first diameter) is advanced into a body lumen. The distal portion of the catheter is caused to expand to a diameter that is larger than the second diameter but no larger than the first diameter. A working device is then advanced out of the distal end of the catheter and used to remove obstructive matter, deliver an implantable device or substance and/or restore flow. The distal portion can be reduced in diameter prior to removal from the body. A stand alone, guide catheter is also disclosed possessing high resistance to kinking even with a very thin wall. | 05-10-2012 |
| 20120116351 | Method of Operating a Microvalve Protection Device - An endovascular valve device for use in a vessel during a therapy procedure includes a catheter having at its distal end a valve. The valve is constructed of a braid of elongate first filaments coupled together at their proximal ends in a manner that the first filaments are movable relative to each other along their lengths. The first filaments have a spring bias that radially expands the valve. A filter is provided to the braid formed by electrostatically depositing or spinning polymeric second filaments onto the braided first filaments. The lumen of the catheter is in communication with the center of the valve. The device is used to provide a therapy in which a therapeutic agent is infused into an organ. | 05-10-2012 |
| 20120165785 | Catheter System for a Needle Injector with an Automatic Needle/Barrier Extension - A catheter system includes a positioning catheter for receiving an injection needle into its lumen. The injection needle incorporates a web member mounted directly onto its shaft. As the injection needle is moved in a distal direction to exit from the lumen of the catheter, the web member is biased to transition from a folded configuration, and into a flared configuration. Specifically, this transition occurs when the injection needle is deployed more than a predetermined distance “d” beyond the distal end of the catheter. In its flared configuration, the web member is disk-shaped and is oriented perpendicular to the needle. Thus, it acts as a barrier to limit the depth of insertion of the needle into target tissue of a patient, to a depth less than “d”, and to prevent perforation of the target tissue by the catheter tip. | 06-28-2012 |
| 20120172837 | METHODS FOR INHIBITING RENAL NERVE ACTIVITY VIA AN INTRA-TO-EXTRAVASCULAR APPROACH - Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. | 07-05-2012 |
| 20120184939 | TUBING SET HAVING AN INSERT FOR THE INFUSION OF DRUGS - The present invention refers to a tubing set ( | 07-19-2012 |
| 20120184940 | BIOARTIFICIAL KIDNEYS - The present invention generally relates to improved bioartificial kidneys (BAKs), and in certain embodiments to improved bioartificial kidneys that are portable and/or wearable by a user. In some embodiments, the BAKs may comprise an ultrafiltration unit and a reabsorption unit. The reabsorption unit may contain a reabsorption membrane having a layer of renal proximal tubule cells disposed thereon, where the renal proximal tubule cells selectively allow solutes to pass through the reabsorption membrane. In some embodiments, at least the reabsorption unit may be configured as a substantially flat-plate filtration device, which can impart advantageous properties such as improved maintenance of the renal proximal tubule cell layer, more facile monitoring of the renal proximal tubule cell layer as well as enhanced profile for wearability. | 07-19-2012 |
| 20120203201 | Methods for Preparing a Heat Exchange Catheter System and for Heating and/or Cooling a Subject's Body - Closed loop heat exchange catheter systems and methods for preparing and using such systems wherein a reservoir or fluid bag is connected to the catheter system and used for at least priming of the system with a heat exchange fluid. | 08-09-2012 |
| 20120203202 | METHOD AND APPARATUS FOR DELIVERING AN AGENT TO A KIDNEY - A method is described including introducing a delivery device to a point within a renal artery or a renal segmental artery and delivering a treatment agent from the delivery device according to conditions that create a turbulent blood flow and wherein the treatment agent is capable of inhibiting a biological process contributing to nephropathy. In other embodiments, an apparatus and kit are described including a delivery device for insertion to a point within a renal artery or renal segmental artery and delivery of a treatment agent capable of inhibiting a biological process contributing to nephropathy. | 08-09-2012 |
| 20120277725 | SYSTEMS AND METHODS FOR ENGAGING HEART TISSUE - A system for engaging heart tissue includes an engagement catheter defining a first lumen therethrough and having a suction port at or near a distal end and a vacuum port at or near a proximal end, a delivery catheter defining a delivery catheter lumen therethrough and configured for slidable insertion into the first lumen of the engagement catheter, and an implantable device capable of insertion into the delivery catheter lumen such that at least part of the implantable device extends from a delivery catheter distal end upon implantation into a patient, where the suction port is operable to removably attach to a targeted tissue on an interior wall of a heart of the patient after the engagement catheter has been advanced through a blood vessel and into the heart, thereby forming a reversible seal with the targeted tissue when a vacuum source is operatively coupled to the vacuum port. | 11-01-2012 |
| 20120296312 | DEVICE AND METHOD FOR COMBINING A TREATMENT AGENT AND A GEL - A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first annular member and a first entry port at a proximal end of the first annular member, and a second annular member coupled to the first annular member having a second lumen disposed about a length of the second annular member and a second entry port at a proximal end of the second annular member, wherein the first annular member and the second annular member are positioned to allow a combining of treatment agents introduced through each annular member at the treatment site. | 11-22-2012 |
| 20120302995 | Localized Therapy Delivery and Local Organ Protection - A system for perfusing a localized site within a body includes a catheter assembly having a venous access line that is adapted to deliver perfusate to the localized site, a venous or arterial drainage line adapted to drain perfusate from the localized site, and an occlusion device adapted to prevent some or substantially all physiological blood flow between the localized site and the systemic circulation of the body during and in the course of perfusing and draining perfusate to and from the localized site. The system may include a blood circuit associated with the catheter assembly to facilitate blood conditioning for use as the perfusate, in the course of a controlled perfusion and/or drainage of untreated, treated, or inactivated treated blood to and from the localized site. A delivery machine may control the blood circuit and catheter assembly in order to both deliver perfusate to, and drain some or all perfusate from, the localized site in a manner that provides perfusate to substantially only the localized site. | 11-29-2012 |
| 20120310209 | Catheter And Treatment Methods For Lower Leg Ischemia - A method of treating lower leg ischemia includes advancing a wire guide upstream through a vascular access sheath extending into an artery, and increasing a downstream flow of blood at least in part by dilating a constriction in the artery with a treatment mechanism guided into the constriction via the wire guide. The method further includes withdrawing a catheter which is coupled with the treatment mechanism from the patient at the percutaneous entry point via sliding the catheter downstream through the vascular access sheath. A low profile balloon may be used as the treatment mechanism, and is advanced through the artery while the vascular access sheath protects the artery from irritation such that spasm of the artery is less likely to occur. Reduced risk of spasm advantageously enables retrograde access to chronic total occlusions such that multiple entry points into a patient's body are not necessary. | 12-06-2012 |
| 20130023852 | Flow Protection Device - A catheter for provides protection to the brachiocephalic and left common carotid arteries against embolic delivery associated with transcatheter aortic valve implantation (TAVI). A catheter having two lumens is introduced into the radial artery and the distal end is delivered to the aorta and an intermediate end is delivered to the brachiocephalic artery. Blood is taken from the aorta and is delivered to the intermediate end via a pump. Fluid flow out of the brachiocephalic artery prevents embolic debris from entering the brachiocephalic artery; streamlines of blood flow into the aorta prevent embolic debris from entering the neighboring left common carotid artery. | 01-24-2013 |
| 20130041348 | Catheter-Based Delivery of Skeletal Myoblasts to the Myocardium of Damaged Hearts - The present invention provides improved systems and methods for the minimally invasive treatment of heart tissue deficiency, damage and/or loss, especially in patients suffering from disorders characterized by insufficient cardiac function, such as congestive heart failure or myocardial infarction. In certain embodiments, a cell composition comprising autologous skeletal myoblasts and, optionally, fibroblasts, cardiomyocytes and/or stem cells, is delivered to a subject's myocardium at or near the site of tissue deficiency, damage or loss, using an intravascular catheter with a deployable needle. Preferably, the cell transplantation is performed after identifying a region of the subject's myocardium in need of treatment. The inventive procedure, which can be repeated several times over time, results in improved structural and/or functional properties of the region treated, as well as in improved overall cardiac function. In particular, the inventive therapeutic methods may be performed on patients that have previously undergone CABG or LVAD implantation. | 02-14-2013 |
| 20130046282 | Method Of Treating An Intravascular Site In A Patient, And Thrombolysis Catheter Therefor - A method of treating an intravascular site in a patient includes spraying jets of treatment fluid out of spray orifices formed in an elongate catheter body, and changing an impingement pattern of the treatment fluid on material within the intravascular site in response to a torque induced by a back pressure of the jets. A thrombolysis catheter includes an elongate catheter body having a plurality of spray orifices formed in a body wall, and communicating with a fluid lumen longitudinally extending in the elongate catheter body. The plurality of spray orifices define a torque inducing spray jet pattern, whereby a back pressure of spray jets exiting the spray orifices induces a torque on the elongate catheter body. | 02-21-2013 |
| 20130131636 | METHODS OF TREATING MEDICAL CONDITIONS BY TRANSVASCULAR NEUROMODULATION OF THE AUTONOMIC NERVOUS SYSTEM - The present invention is directed to a method of treating a respiratory or pulmonary condition by transvascular neuromodulation of a target site adjacent to an adrenal gland. A method for treating a respiratory or pulmonary condition via transvascular neuromodulation incorporating a closed-loop feedback system is also provided. | 05-23-2013 |
| 20130138080 | MEDICAL ARTICLE WITH ROTATABLE WINGS - A medical article is configured to provide access to a patient's vasculature. The medical article includes an elongated body and a pair of stabilizing wings that extend from the elongated body and are configured to stabilize the medical article on a patient. The stabilizing wings are configured to rotate together or independently about the longitudinal axis of the elongated body between at least a first configuration and a second configuration. The elongated body can include a one-way valve disposed therein. The medical article can also one or more adhesive layers configured to releasably attach at least a portion of the wings to a patient. | 05-30-2013 |
| 20130158509 | SYSTEM, APPARATUS, AND METHOD FOR DENERVATING AN ARTERY - The present disclosed subject matter is directed to a less invasive surgical system, apparatus and method including a guidable catheter for providing electroporation therapy to a subject suffering from heart or kidney disease. The system includes an electrical generator and an apparatus for denervating an artery. The apparatus includes a catheter having a proximal end, a distal end, a first lumen with a first exit port, a second lumen having a second exit port. The apparatus also includes a first needle including a first electrode. The apparatus also includes a displacement mechanism engaged to the catheter near the proximal end such that the displacement mechanism controls the linear position and angular position of the catheter. | 06-20-2013 |
| 20130172851 | DISTAL ACCESS ASPIRATION GUIDE CATHETER - Distal access aspiration guide catheter system and methods for delivering implantable devices, catheters, or substances in or near and/or restoring flow through body lumens, such as blood vessel lumens are described. A distal access aspiration guide catheter having a proximal, medial, and distal possessing high flexibility, high resistance to kinking and a large lumen to wall thickness ratio. | 07-04-2013 |
| 20130172852 | ENDOLUMINAL DELIVERY OF ANESTHESIA - Described herein are methods and devices for selectively applying fluids (particularly anesthetics) to a target tissue from within a blood vessel while minimizing the amount of fluid applied to non-target tissue. The injection catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter before extending the injector. The methods of selectively applying anesthetic to a target structure generally include the steps of inserting an injection catheter into a body vessel, positioning the injection catheter within the body vessel near the target structure, anchoring the injection catheter before extending a directional injector from the injection catheter, and applying anesthetic from the injection catheter to the target structure. | 07-04-2013 |
| 20130184679 | DEVICE FOR DELIVERY OF ANTIMICROBIAL AGENT INTO TRANS-DERMAL CATHETER - A system, method, and article for delivering an antimicrobial agent into the lumen of a trans-dermal catheter are disclosed. In an embodiment, the system comprises an elongate member configured for insertion into a lumen of a catheter, and the elongate member containing an antimicrobial. In the alternative an antimicrobial agent can be placed on an interior surface of a retaining ring. | 07-18-2013 |
| 20130190724 | PREVENTION OF INDWELLING DEVICE RELATED INFECTION: COMPOSITION AND METHODS - Catheters used for medical treatment, e.g., hemodialysis are filled with a locking solution, usually heparin between treatments. To prevent infections, antimicrobial or antibiotic substances have been used as locking solution alone or in combination with antithrombotic substances. It has been found that these locking solutions are rapidly washed out from the catheter tip. The invention describes a thixotropic gel that can be used as locking solution. Beneficial substances, e.g., antimicrobial or antibiotic substances can be added to the gel. A preferred antimicrobial substance is taurolidin alone or in combination with salicylic acid or one of its salts. | 07-25-2013 |
| 20130204230 | Expandable Catheter - A fluid delivery mechanism that has a substantially cylindrical sleeve and an actuator coupled to the sleeve for controlling a circumference of the sleeve. | 08-08-2013 |
| 20130204231 | METHOD FOR APPLYING ANTIMICROBIAL TO PROXIMAL END OF CATHETER - Systems, methods, and articles for delivering an antimicrobial composition to the proximal elements of a trans-dermal catheter and into the lumen of the transdermal catheter are disclosed. In an embodiment, an antimicrobial composition placed on an interior surface a cap element, and transfers antimicrobial to the exterior of the proximal end of the transdermal catheter. The system comprises an elongate member configured for insertion into a lumen of a catheter, the elongate member containing an antimicrobial. | 08-08-2013 |
| 20130211378 | PUMP AND MONITOR FOR IV PRESSURE INFUSERS - A pumping device that can be used with currently-available pressure bag infusers is disclosed. The pumping device is hand-held and lightweight. The device is controlled by a microprocessor. Thus constant pressure to the bag is maintained through automatic adjustment of pumping and venting functions. In addition, a novel, new pressure bag infuser and a modified Luer Lock fitting for use with the pumping device are described. | 08-15-2013 |
| 20130211379 | CATHETER ASSEMBLY AND METHOD OF TREATING A VASCULAR DISEASE - A catheter assembly comprises a catheter including a catheter wall and a lumen extending lengthwise of the wall. The wall has inner and outer surfaces. The wall includes plural openings that extend through the wall and communicate with the lumen. An elongated hollow needle includes a proximal end portion and a distal end portion. The needle is movable in the lumen to move the distal end portion between the openings. The distal end portion is directed radially outward so as to extend into an adjacent opening. The distal end portion has a configuration that stores potential energy when in the lumen. The potential energy is converted to kinetic energy to produce movement of the proximal end portion as the distal end portion moves from the inner surface of the catheter wall across an edge of an opening. The movement of the proximal end portion is haptically perceptible. | 08-15-2013 |
| 20130211380 | Compartmentalized method of nucleic acid delivery and compositions and uses thereof - Provided herein is a method of delivering nucleic acid molecules to a compartmentalized tissue or organ of a subject. Also provided herein are uses and processes for delivering a nucleic acid molecule to the parenchyma of a compartmentalized tissue or organ. The methods and uses can be used in the treatment of diseases and conditions and in industrial, agricultural and veterinary applications. Also provided herein are compositions containing an adenovirus or adeno-associated virus or other recombinant virus formulated for administration to the parenchyma of a tissue or organ. | 08-15-2013 |
| 20130226145 | PRESSURE ACTIVATED SAFETY VALVE WITH GROOVED MEMBRANE - A pressure activated valve comprises a valve housing defining a linen for receiving bodily fluids therein and a flexible membrane disposed in the valve housing. The flexible membrane includes a slit extending therethrough so that the flexible membrane may be moved between an open and a dosed configuration based on fluid pressure within the lumen. A nonthrombogenic coating may be formed on fluid contacting surfaces of the flexible membrane. | 08-29-2013 |
| 20130274711 | Variable Infusion Length Catheter And Method - A variable infusion length catheter includes a tube assembly having a plurality of coaxial tubes each with a plurality of side ports formed therein, and having among the tubes a plurality of different rotational configurations each defining a different pattern of fluid communication among the side ports and a corresponding different infusion length of the catheter. Related methodology is also disclosed. | 10-17-2013 |
| 20130281978 | EXPANDABLE TRANS-SEPTAL SHEATH - Disclosed is an expandable transluminal sheath, for introduction into the body while in a first, low cross-sectional area configuration, and subsequent expansion of at least a part of the distal end of the sheath to a second, enlarged cross-sectional configuration. The sheath is configured for use in the vascular system and has utility in the performance of procedures in the left atrium. The access route is through the inferior vena cava to the right atrium, where a trans-septal puncture, followed by advancement of the catheter is completed. The distal end of the sheath is maintained in the first, low cross-sectional configuration during advancement to the right atrium and through the atrial septum into the left atrium. The distal end of the sheath is subsequently expanded using a radial dilatation device. | 10-24-2013 |
| 20130289526 | ENDOVASCULAR CATHETER AIR BLOCK - This invention is an air block for industrial, medical, and non-medical uses. For example, the air block is connected to the proximal end of a vascular access catheter. The air block is either removably connected to the proximal end of the catheter or it is integral to the proximal end of the catheter. The air block permits introduction of other catheters or instrumentation through its central lumen and on into a lumen of the catheter while minimizing fluid loss or gain into the catheter. The air block further prevents air from entering the catheter and provides for removal of the air or other gas from the central lumen before it can enter the catheter where it could cause harm to the patient. The air block can be attached to various standard proximal catheter terminations including Luer fittings and hemostasis valve outer barrels. | 10-31-2013 |
| 20130289527 | CATHETER DEVICE - A catheter assembly comprising an elongated tubular structure having a distal end and a proximal end; a septum disposed within the interior of the tubular structure so as to define a first lumen and a second lumen, and a valve element disposed at the distal end of the tubular structure and configured to move longitudinally relative to the tubular structure between (i) a closed position in which the distal end of the tubular structure is closed off by the valve element, and (ii) an open position in which the distal end of the tubular structure is not closed off by the valve element; wherein the tubular structure, septum and valve element are configured so as to provide fluid communication between the first and second lumen when the valve element is disposed in its closed position. | 10-31-2013 |
| 20130304028 | CATHETER CLAMPS AND CATHETERS - Provided are devices and methods for reducing or preventing fluid flow through a catheter lumen. For example, the devices and methods can be used to reduce blood flow through a catheter. Optionally, the catheter is an intravenous catheter. Also provided are catheters. | 11-14-2013 |
| 20130310803 | Clot Removal Device and Method of Using Same - A minimally invasive endovascular device for treating a blocked or obstructed biological lumen, such as a blood vessel fully or partially obstructed by deposits of biological matters in or non-biological matters. Certain embodiments of the present invention comprise two capture members that are configured to be placed on either side of the obstruction and enclose around the obstruction for removal. Embodiments of the present invention also provide methods for implementing an endovascular device according to aspects of the present invention. | 11-21-2013 |
| 20130345675 | HIGH FLOW RATE ISOLATED INFUSION FOR REGIONAL TREATMENT OF CANCER AND MEDICAL CONDITIONS - The present application relates to high flow rate isolated regional treatment of cancer and proliferative disorders and conditions. For example, provided are methods, systems and devices for treating a cancer in a region of a subject using high flow rate isolated infusion. | 12-26-2013 |
| 20140018772 | SELF-CENTERING CATHETER WITH ANTI-OCCLUSION FEATURES - Disclosed herein are various embodiments of catheters configured to reduce, minimize or prevent occlusion of blood flow resulting from thrombus or fibrin sheath formation, related systems, and methods of use. | 01-16-2014 |
| 20140025037 | Method and Apparatus for Intra-Aortic Substance Delivery to a Branch Vessel - A renal flow system injects a volume of fluid agent into a location within an abdominal aorta in a manner that flows bi-laterally into each of two renal arteries via their respectively spaced ostia along the abdominal aorta wall. A local injection assembly includes two injection members, each having an injection port that couples to a source of fluid agent externally of the patient. The injection ports may be positioned with an outer region of blood flow along the abdominal aorta wall perfusing the two renal arteries. A flow isolation assembly may isolate flow of the injected agent within the outer region and into the renals. The injection members are delivered to the location in a first radially collapsed condition, and bifurcate across the aorta to inject into the spaced renal ostia. A delivery catheter for upstream interventions is used as a chassis to deliver a bilateral local renal injection assembly to the location within the abdominal aorta. | 01-23-2014 |
| 20140039457 | INFUSION SET IMPROVEMENTS - A method and device for adjusting the unstored length of tubing directed to improving the use of infusion sets that deliver fluids to a user. The device includes a storage module and other features for adjusting, storing and securing the length of the tubing. The method of adjusting the length of the tubing to a desired length typically comprises removably attaching the tubing to the adjuster, adjusting the tubing by wrapping the tubing around a hub or post of the adjuster, and fixing the length of the unstored tubing by attaching the tubing to a securing device such as a friction structure or fastener. | 02-06-2014 |
| 20140039458 | Compact Spring Inserter For Drug Delivery Infusion Set - An infusion set ( | 02-06-2014 |
| 20140046297 | Distal Access Aspiration Guide Catheter - Distal access aspiration guide catheter system and methods for delivering implantable devices, catheters, or substances in or near and/or restoring flow through body lumens, such as blood vessel lumens are described. A Distal access aspiration guide catheter having a proximal, medial, and distal possessing high flexibility, high resistance to kinking and a large lumen to wall thickness ratio. | 02-13-2014 |
| 20140046298 | METHODS OF TREATING ATRIAL FIBRILLATION - At the present time, physicians often treat patients with atrial fibrillation (AF) using radiofrequency (RF) catheter systems to ablate conducting tissue in the wall of the Left Atrium of the heart around the ostium of the pulmonary veins. These systems are expensive and take time consuming to use. The present invention circular ablation system CAS includes a multiplicity of expandable needles that can be expanded around a central axis and positioned to inject a fluid like ethanol to ablate conductive tissue in a ring around the ostium of a pulmonary vein quickly and without the need for expensive capital equipment. The expansion of the needles is accomplished by self-expanding or balloon expandable structures. The invention includes centering means so that the needles will be situated in a pattern surrounding the outside of the ostium of a vein. Also included are members that limit the distance of penetration of the needles into the wall of the left atrium. The present invention also has application to ablating tissue around the ostium of a renal artery for the treatment of hypertension. | 02-13-2014 |
| 20140052103 | DEVICES AND SYSTEMS FOR THROMBUS TREATMENT - A thrombus treatment device includes a support wire, a body frame portion that is disposed about an axis defined by the support wire, one or more tethers that each have a first end and a second end, and a filter element extending from the body frame portion. Each of the one or more tethers is attached at its first end to the body frame portion, and at its second end to a collar that couples the second end of each of the multiple tethers to the support wire. When the collar is positioned substantially within a region interior of the body frame portion, a rotational actuation of the support wire causes a swiveling motion of the one or more tethers. | 02-20-2014 |
| 20140058356 | In Situ Blood Vessel and Aneurysm Treatment - Treatment of aneurysmal blood vessels with local delivery of therapeutic agents thereby reduces or lessens the severity of an aneurysm, and, where used in conjunction with the placement of an excluding device, provides for more rapid recovery of the blood vessel from any disturbance occurring during placement of the excluding device. Therapeutic agents are placed in the aneurysmal site in a time-release carrier medium, such that the therapeutic agent is released into the aneurysmal site over a period of time without the need to provide systemic introduction of the therapeutic agent. The carrier may be introduced through the patient's dermis, such as with the use of a laparoscope, or intravascularly, through the use of a catheter. The carrier may be in a solid matrix, viscous liquid or liquid form. | 02-27-2014 |
| 20140081240 | METHOD OF DELIVERING VECTORS TO PANCREAS AND LUNGS BY CANNULATING THE AORTA - The present invention relates to a safe and effective way to deliver and express therapeutic compositions (e.g., transgenes) to the pancreas and lungs of a mammal. | 03-20-2014 |
| 20140088559 | Multi-Dose Medical Fluid Injection System Having Patient-Specific Tubing Set with Use Indicator - A single-use, single-patient, or patient-specific tubing set ( | 03-27-2014 |
| 20140100547 | CATHETER/FISTULA NEEDLE TO BLOODLINE CONNECTION ASSURANCE DEVICE - In general, multiple embodiments of a catheter/fistula needle to bloodline connection assurance device, which secures and strengthens a connection between an extension tube end of a catheter or fistula needle and a bloodline, are provided. In one embodiment, the assurance device includes a clamshell having two halves that open rotatably about at least one hinge. The assurance device includes a male luer portion that pressure seals to the male luer portion of the bloodline connector. The bloodline male luer portion of the device extends to a female luer portion, which is lined with a compressible material that conforms around any industrial catheter/fistula needle connector when the assurance device is closed about the mated connectors. Once the assurance device is closed, this prevents axial movement of the bloodline connector relative to the assurance device. | 04-10-2014 |
| 20140100548 | CATHETER/FISTULA NEEDLE TO BLOODLINE CONNECTION ASSURANCE DEVICE - In general, multiple embodiments of a catheter/fistula needle to bloodline connection assurance device, which secures and strengthens a connection between an extension tube end of a catheter or fistula needle and a bloodline, are provided. A first embodiment of the assurance device is configured for use with a bloodline connector having locking clips which are biased slightly outwardly from the bloodline connector. The first embodiment of the assurance device includes clamshell halves that open rotatably about at least one hinge. The first embodiment of the assurance device includes an upper, threaded portion and a lower housing portion. The interior wall of the upper portion defines a plurality of barbs configured to engage with distal or moveable ends of the locking clips. Each locking clip is biased slightly outwardly to enable the distal or moveable end of the locking clip to fit between two respective barbs. | 04-10-2014 |
| 20140100549 | FOLLOW-UP OF THE VASCULAR ACCESS OF A DIALYZED PATIENT - The invention relates to a calculation and control system for the determination of the state of a vascular access of a patient intended to follow successive sessions of extracorporeal blood treatment by extraction and return of the blood via the vascular access, the system comprising: means for determining the value of at least one hemodynamic extracorporeal parameter of the patient for at least two sessions; means for determining the value of the purification effectiveness of the treatment for at least two sessions; programmed means for determining a risk score relating to the state of the vascular access of the patient as a function of at least two values of the hemodynamic extracorporeal parameter and of at least two determined values of the purification effectiveness. | 04-10-2014 |
| 20140107614 | Connection System for Multi-Lumen Catheter - A catheter connection system and a method of connecting the catheter connection system to a catheter. The catheter connection system includes a hub assembly and a collar. The hub assembly includes a cannula extending from a distal end thereof, and a collet defining an inner surface spaced apart from the cannula to permit passage of a catheter wall between the body and the cannula. | 04-17-2014 |
| 20140135734 | DEVICES AND METHODS FOR DELIVERING VASCULAR IMPLANTS - Embodiments of the present disclosure are directed to delivery devices, methods, and systems for delivering an implant to a target site. In one embodiment, a delivery device includes a core member defining a proximal end and a distal end and an outer winding defining a proximal end and a distal end, wherein the outer winding surrounds and is coupled to the core member. The outer winding extends at least partially between the proximal end of the core member and the distal end of the core member, and the outer winding is configured for displacement within a delivery catheter. The delivery device further includes a coupling member at the distal end of the core member configured to releasably attach to an implant. | 05-15-2014 |
| 20140142546 | Low-Profile Intravenous Catheter Device - An intravenous catheter device and system includes: (a) a medical tubing connector at a first end of the intravenous catheter device; (b) a length of flexible, non-kinking, supported medical tubing, a first end of the non-kinking tubing being connected to a first end of the medical tubing connector; (c) an intravenous catheter portion having a first end attached to a second end of the non-kinking tubing, the non-kinking tubing extending between the intravenous catheter portion and the tubing connector; and (d) a cylindrical-shaped cuff attached to a fast outside end portion of the intravenous catheter portion, and a second outside end portion of the non-kinking tubing; wherein a central channel of the intravenous catheter portion is in fluid communication with a channel of the non-kinking, flexible tubing when the intravenous catheter device is in use. This simplified abstract is not intended to limit, and should not be interpreted as limiting, the scope of the claims. | 05-22-2014 |
| 20140148787 | ELONGATE FLEXIBLE TORQUE INSTRUMENTS AND METHODS OF USE - Torque shafts and other related systems and methods are described herein. In one embodiment, the torque shafts are both flexible and capable of transmitting torque. An apparatus for transmission of torque includes an elongate body, comprising a plurality of joint segments, each joint segment configured to pivot with respect to an adjacent segment and being further configured to have at least two link elements. | 05-29-2014 |
| 20140148788 | SELECTIVELY POSITIONABLE CATHETER CUFF - Devices and methods for securing a catheter with the body of a patient are generally disclosed. In particular, selectively positionable cuffs and methods for attaching selectively positionable cuffs to long-term tunneled catheters are disclosed. In one embodiment, a slidable, selectively-positionable cuff comprises an adhesive on a foldable tab. In another embodiment, a slidable, selectively positionable cuff comprises an activatable adhesive that is convertible from a nonadherent state to an adherent state beneath the skin of the patient. Additionally, the present disclosure teaches a wrappable sheet comprising a harvested extracellular matrix with an adhesive positioned on a side thereon and arranged to be adhered to the surface of a catheter so as to form a cuff. Methods of securing and/or positioning a cuff on a catheter, kits, and other embodiments are disclosed. | 05-29-2014 |
| 20140155862 | DEVICES AND METHODS FOR PERFUSION THERAPY - Devices, methods, and assemblies for perfusion therapy including cerebral perfusion therapy such as those for use in the treatment of acute ischemic stroke. The treatment includes delivery of blood to or about the vicinity of a thrombus site. | 06-05-2014 |
| 20140155863 | METHOD FOR A CENTRAL VENOUS LINE CATHETER HAVING A TEMPERATURE CONTROL SYSTEM - A kit of parts comprises a system and instructions for use for controlling patient temperature which uses a central venous line catheter having a heat exchange element. The central venous line catheter is provided with one or more lumens for providing access to the central blood supply of the patient, and with additional lumens for communicating heat exchange fluid to the heat exchange element. Heat exchange fluid temperature is controlled through a feed back loop in which patient temperature is sensed and used to control a temperature control unit comprising a heating device and/or a cooling device in heat exchange relationship with the heat exchange fluid. A tubing set transports the heat exchange fluid between the central venous line and the temperature control unit, with a pump serving to circulate the fluid in a closed fluid circuit in the system. | 06-05-2014 |
| 20140163523 | Folding Inserter For Drug Delivery Infusion Set - An infusion set ( | 06-12-2014 |
| 20140163524 | DUAL PLUNGER BASED SYSTEMS AND METHOD FOR USE IN DETERMINING A VOLUME IN A RESERVOIR - A system, for use in determining a volume in a reservoir, includes a bulkhead, a plunger assembly, and a base. The plunger assembly is connected to the bulkhead. The plunger assembly includes a first plunger and a second plunger. The first plunger has a corresponding first biasing member. The second plunger has a corresponding second biasing member. The base of the reservoir is connected to the first plunger. Movement of the base causes compression or expansion of the first biasing member, which causes compression or expansion of the second biasing member. The bulkhead, the first plunger, and the base define a first portion of the reservoir. Positions of the first plunger and the base, relative to the bulkhead, are based on the volume in the reservoir. | 06-12-2014 |
| 20140171907 | LIQUID EMBOLIC MATERIAL INCLUDING CARBOXYMETHYL CHITOSAN CROSSLINKED WITH CARBOXYMETHYL CELLULOSE - A liquid embolic material may include a mixture of a first solution comprising between about 1.2% and about 2.5% weight per volume (w/v) carboxymethyl chitosan (CCN) in a first solvent and a second solution comprising between about 1.2% and about 2.5% w/v oxidized carboxymethyl cellulose (OCMC) in a second solvent. The liquid embolic material may be used to embolize a targeted embolization location by mixing the first solution and the second solution to form a liquid embolic material (or hydrogel precursor material), introducing the hydrogel precursor material to a targeted embolization location within a body of a patient, and allowing the CCN and the OCMC to react to form the hydrogel material and embolize the targeted embolization location. | 06-19-2014 |
| 20140171908 | Intra-Myocardial Agent Delivery Device, System and Method - An intra-myocardial agent delivery device comprising a myocardial tissue access line that is configured to receive a pharmacological agent therein and at least a first agent delivery line having a central lumen therethrough, the first agent delivery line being in fluid communication with the tissue access line and including a plurality of dispersal lumens extending through the delivery line wall, wherein, when the first agent delivery line is disposed in myocardial tissue and the pharmacological agent is introduced into the tissue access line, the plurality of dispersal lumens allow the pharmacological agent to be transferred from the central lumen to the myocardial tissue. | 06-19-2014 |
| 20140171909 | Tunneling System - A tunneling system for use with a catheter includes an elongate tunneling member defining a longitudinal axis along at least a portion of a longitudinal length thereof. The elongate member has a first end and a second end. The tunneling system further includes a connector configured for releasably engaging the second end of the elongate tunneling member to the catheter. | 06-19-2014 |
| 20140171910 | Treatment Fluid Delivery Method, And Turbulator For Promoting Uptake Of A Treatment Agent - A turbulator for promoting mixing of fluids passing through a body lumen includes an elongate flow perturbing component and an elongate shape controlling component freely slidable within the flow perturbing component. The turbulator is adjustable from a low profile, lumen access configuration to a deployed configuration via sliding the shape controlling component within the flow perturbing component. Adjusting the turbulator within a body lumen of a patient induces turbulence within a flow of fluid passing through the body lumen to increase mixing of a treatment fluid with the body fluid by way of the induced turbulence. | 06-19-2014 |
| 20140180246 | ASSEMBLIES, SYSTEMS, AND METHODS FOR INFUSING THERAPEUTIC AGENTS INTO THE BODY - An infusion catheter assembly has the ability to infinitely titrate the length of a porous fluid distribution section in situ. The infusion catheter assembly thereby provides a length of infusion that can be infinitely varied over a prescribed range, to control the effective infusion length and the rate of infusion. Using the infusion catheter assembly, a physician has the capability to treat only the length of the vessel desired, thereby preventing excessive drug/patient exposures. The porous fluid distribution section can include an array of spaced apart apertures that vary in size and/or density along the length of the porous fluid distribution section, such that the flow rate remains essentially constant for a given inlet pressure independent of the effective infusion length. | 06-26-2014 |
| 20140188078 | CATHETER SECUREMENT DEVICE - A securement system ( | 07-03-2014 |
| 20140188079 | APPARATUS AND METHOD FOR CONTROLLING VISIBILITY AND ACCESS TO CENTRAL VENOUS ACCESS DEVICES - A device for controlling visibility and access to central venous access devices is comprised of a two-sided body fitted around the torso of a patient. The device has an interior surface and an exterior surface. The interior surface is fitted with a layer of absorbent, wicking material and further includes strips of anti-slip material to fix the device in place. A flexible window is positioned between two lumen retaining flaps and fixed between the interior and exterior surfaces. A pair of indentions is positioned above and below the window. A pair of locking closures is attached to the body over the indentions. The body includes a flexible closure including a resilient gauze section to provide flexibility and size adjustability. The window allows visual access to the intravenous site and prevents patient tampering. The intravenous lines are protected from breakage and tampering by the locking closures, indentions, and lumen retaining flaps. | 07-03-2014 |
| 20140194853 | CONNECTOR HUB APPARATUS FOR CATHETER AND METHODS OF USE - A hub assembly is provided for accommodating a medical professional to grip and manipulate two components of a catheter hub and move one component longitudinally relative to the other, then removably engaging the two components of the catheter hub to restrict movement there between. The two catheter hub components include a proximal hub and a distal hub. The proximal hub and the distal hub are configured to removably engage with one another. The proximal hub is affixed to a first catheter member, such as a multi-lumen catheter, while the distal hub is affixed to a second catheter member, such as a sheath. The first catheter member and the second catheter member are cooperatively engaged and concentric with one another. Relative movement of the proximal and distal hubs translates into relative movement of the first and second catheter members. | 07-10-2014 |
| 20140200549 | IV CATHETER FOR PREVENTING BACKFLOW - The present invention provides an improved intravenous (IV) catheter that enables a hands free means of preventing backflow of blood. The disclosed device incorporates a flow back inhibitor that includes leaflets radially layered upon one another in a conical form. In open mode the leaflets allow fluid flow and in closed mode the leaflets inhibit fluid flow. The device is attachable to a patient by means of an attachment component. | 07-17-2014 |
| 20140221975 | APPARATUS AND METHODS FOR TREATING PULMONARY HYPERTENSION - A method is described for decreasing activity of at least one sympathetic nerve, nerve fiber or neuron innervating at least one blood vessel in the pulmonary vasculature of a patient to ameliorate pulmonary hypertension. In one embodiment, the method may involve advancing an intravascular treatment device to a target location in a target blood vessel within the pulmonary vasculature of the patient and using the treatment device to decrease activity of at least one sympathetic nerve, nerve fiber or neuron innervating the target blood vessel at or near the target location to ameliorate pulmonary hypertension. | 08-07-2014 |
| 20140243789 | Subcutaneous Dialysis Catheter with Ultrasound Agitation - A subcutaneous, venous catheter is provided in conjunction with a method of installation in hemodialysis treatments. The catheter has an implantable hub attached to a first end of the primary lumen. An anchoring back plate is pivottably secured to the catheter hub and surgically anchored to underlying musculature. Once the device is implanted, the hub can be arcuately translated underneath the skin by applying gentle pressure to either side of the hub. To reduce fluid stagnation within and around the lumen, a series of piezo-electric elements are integrated therein. A vibration processor is electrically connected to the piezo-electric elements such that the initiation of electrical current by the vibration processor results in contraction of the piezo-electric elements. Expansion and contraction of these elements propagates low-energy acoustic waves through the lumen, agitating liquid contained therein and improving flow of same through the catheter lumen. | 08-28-2014 |
| 20140249505 | Method and System of Utilizing ECG Signal for Central Venous Catheter Tip Positioning - Disclosed herein are a method and a medical system for utilizing of a intravascular ECG signal for central venous catheter placement. The medical system is capable of detecting the position of a catheter tip and assessing its location relative to the cavoatrial junction. The detection and assessment are performed by a multiscale analysis of the complexity of the intravascular signal data points. | 09-04-2014 |
| 20140257242 | ALL IN ONE ANTIMICROBIAL DRESSING FOR CATHETER COVERAGE - We have disclosed dressing devices that combine the functions of coverage of a catheter insertion site, fluid handling capacity for the puncture site of a catheter, and fixation of the catheter. More specifically, we have disclosed dressing devices comprising a base, a pad, and a dressing film, and the devices possess antimicrobial properties. We further disclose a method of making the disclosed dressing devices, a kit comprising the disclosed dressing devices and a catheter fastener means, a method of installing the dressing devices on a patient's skin over an indwelling catheter, and a method of replacing the disclosed dressing devices. | 09-11-2014 |
| 20140257243 | CONTROLLING CATHETER FLOW - A catheter assembly includes an elongate member and a balloon. The elongate member defines at least one lumen and an outer surface. The outer surface defines at least one opening in fluid communication with the at least one lumen. The balloon is disposed within the at least one lumen. The balloon is inflatable such that a portion of the balloon expands from the at least lumen through the at least one opening. The expansion of the balloon increases the flow restriction through the at least one opening compared to the flow restriction through the at least one opening when the balloon is in a deflated condition. Methods for using a catheter assembly to remove occlusive material from a catheter are also described. | 09-11-2014 |
| 20140257244 | FLUSHING STYLET - Systems and methods for use medical procedures including catheters and stylets are disclosed. The catheter includes a wall having an inner surface and an outer surface, the inner surface defining a lumen, and the wall defining at least one side opening from the outer surface to the inner surface. The stylet includes an elongate body defining a passage and at least one aperture in fluid communication with the passage. The stylet also includes a first blocking dam secured to the elongate body proximal to the at least one aperture and a second blocking dam secured to the elongate body distal to the at least one aperture. The stylet is movable within the lumen to a position in which the first and second blocking dams are, respectively, proximal and distal to the at least one side opening of the catheter and each of the first and second blocking dams is sealingly enaged with the inner surface of the catheter such that fluid introduced into the lumen, from the passage and through the at least one aperture of the stylet, is directed through the at least one side opening of the catheter. | 09-11-2014 |
| 20140276601 | CATHETER STIFFNESS ADJUSTMENT SYSTEM AND METHOD - A catheter stiffener adjustment system including a first member with an outer diameter and having at least three first segments with at least one joint enabling the segments to bend relative to each other, and a second member having an inner diameter defining a passageway through which the first member is movable relative to the second member. The second member has at least three second segments with at least one joint enabling the segments to bend relative to each other. In a first position, the first segments and the second segments are alignable substantially in phase to generate a first flexure condition. In a second position, the first segments and the second segments are alignable substantially out of phase to generate a second, stiffer flexure condition. | 09-18-2014 |
| 20140276602 | CATHETER SYSTEM - A multi-station hydrodynamic catheter includes an outer catheter having a first lumen, the outer catheter having a plurality of orifice stations positioned along a portion of the outer catheter, where each orifice station includes one or more orifices extending from an outer catheter external surface to the first lumen. The multi-station hydrodynamic catheter includes an inner catheter having a second lumen, the inner catheter movable within the first lumen and includes at least one emanator, where the at least one emanator includes one or more fluid delivery ports extending from an inner catheter external surface to the second lumen. | 09-18-2014 |
| 20140276603 | INTELLIGENT CATHETER - A system includes a microprocessor executable verification module in a base unit and a microprocessor readable identifier of an endovascular device in a memory of the endovascular device. The microprocessor executable verification module, based on the identifier, at least one of configures the endovascular device for use and determines whether the endovascular device can be enabled for use. | 09-18-2014 |
| 20140276604 | Medical Tube Securing Device - A medical tube securing device including: (a) an anchor that can be attached to the skin of a patient, wherein at least one opening extends through the anchor and is shaped and sized to receive a medical tube; (b) a first padding layer having a first side and a second side, wherein the first side of the first padding layer is joined to the anchor and has at least one opening that extends through the first side and the second side of the first padding layer; (c) at least one clasp joined to the second side of the first padding layer, wherein the clasp receives and holds in place a portion of the medical tube; and (d) a second padding layer. A method of securing a medical tube is also disclosed. | 09-18-2014 |
| 20140276605 | CATHETER FOR VASCULAR INTERVENTIONS - Embodiments provide adjustable vascular catheter systems suitable for use in radial access procedures. In embodiments, the adjustable catheter includes an elongated tubular member having a wall defining a proximal end, a distal end, and a main lumen extending therebetween; a first micro-lumen having a proximal end, a distal end, and a hollow lumen extending therebetween, wherein the first micro-lumen extends substantially outwardly from the catheter wall and runs in parallel with the main lumen; and a first shape wire adapted to pass within the first micro-lumen, wherein the first shape wire has a shape memory function sufficient to deflect a deflectable distal portion of the elongated tubular member. In various embodiments, the shape of the deflected distal portion may allow a user to navigate the catheter past one or more tortuosities and reach normally positioned and anomalous positioned vascular ostia. Some embodiments include second and third shape wires, each having a different shape memory function. | 09-18-2014 |
| 20140276606 | MOVEABLE CUFF - Disclosed is a catheter assembly that includes a catheter, a sheath on the catheter, a sleeve on the sheath and a tissue ingrowth cuff affixed to the sleeve. The sleeve and sheath are movable along the length of the catheter with the sheath being removable from between the sleeve and the catheter. When the sheath is removed, the sleeve becomes substantially fixed in position on the catheter. The sheath may have a comparatively low coefficient of friction against the catheter while the sleeve may have a comparatively high coefficient of friction against the catheter. | 09-18-2014 |
| 20140276607 | MOVEABLE CUFF - Embodiments of the disclosed positioning systems can include a catheter assembly having a catheter with an external surface and an outer diameter, and a movable cuff assembly engaged around the circumference of the catheter. An exemplary movable cuff assembly includes a sleeve, a tissue ingrowth cuff affixed to the sleeve, and a clamp affixed to the sleeve, where when the first clamp is engaged, the movable cuff assembly is substantially fixed in position on the external surface of the catheter and wherein when the first clamp is disengaged, the movable cuff assembly is slidably movable over the external surface of the catheter. | 09-18-2014 |
| 20140288531 | Methods for Bilateral Renal Neuromodulation - Methods and apparatus are provided for bilateral renal neuromodulation, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney. | 09-25-2014 |
| 20140296829 | INTEGRATED VASCULAR DELIVERY SYSTEM - An integrated vascular delivery system and method of use, the system including: a frame having a catheter hub that provides a first anchoring point on the patient and receives a catheter insertable in the patient to transfer fluid at an insertion site, a stabilization hub that provides a second anchoring point on the patient, at least one lateral member extending between the catheter and stabilization hubs, and a fluidic channel. The frame operates in a folded configuration in which the hubs are coupleable and an unfolded configuration in which the anchoring points are distributed around the insertion site to anchor the frame to the patient, thereby stabilizing the catheter. In some embodiments, the system further includes a septum that helps prevent fluid leakage from the catheter hub, or a needle shield that covers the distal end of a needle used during catheter insertion. | 10-02-2014 |
| 20140303595 | CATHETER INJECTION PORT LOCK - A lock for an outpatient's peripherally inserted central catheter (PICC) line limits access to the catheter by patients seeking to abuse injectable narcotics. The lock has two plastic housing halves which slide together, and which define an interior enclosure which receives the catheter line injection port. The housing halves have overlying flanges, through which a fastener extends to secure the device in a closed configuration. The fastener interacts with the flanges in such a way that it cannot be removed without distorting the device and giving evidence of tampering. A zippered sleeve may be provided which surrounds the line leading to the injection port and which has a pull tab which may be engaged within the housing to further prevent access to the line directly. | 10-09-2014 |
| 20140316380 | DEVICES AND METHODS FOR MAINTAINING AN ASEPTIC CATHETER ENVIRONMENT - A device for maintaining an aseptic catheter environment is provided. The device includes a first housing and a second housing. The first housing and the second housing are coupled to one another by way of at least one coupler. The first housing and the second housing are configured to engage one another when in a closed configuration and to define an interior space when in the closed configuration. At least one aperture and/or notch is defined within at least one of the first housing and the second housing. The at least one aperture and/or notch is sized and shaped to allow at least part of a catheter to be positioned therethrough. | 10-23-2014 |
| 20140324024 | CATHETER RETENTION DEVICE - Embodiments provide catheter retention devices such as catheter clips that may be used to stabilize a vascular access catheter during a procedure, particularly a radial access procedure. The catheter clips may include a frame that includes a first frame member portion, a second frame member portion hingeably coupled to the first frame member portion, the first and second frame member portions defining a first aperture therebetween, and a base member extending from the second frame member; and an inner gripping membrane that includes a first inner gripping membrane portion coupled to the first frame member portion and a second inner gripping portion coupled to the second frame member portion, wherein the first and second inner gripping portions define a second aperture within the first aperture. | 10-30-2014 |
| 20140330250 | BI-DIRECTIONAL PERFUSION CANNULA - A bi-directional perfusion cannula is provided that includes an elongate tube for insertion into an artery. The elongate tube has a first aperture at a distal end of the tube which is forward during insertion and configured so that blood can flow into the artery in the direction of insertion, an elbow formed in the elongate tube, and a second aperture formed in or slightly rearward of the elbow and configured for supplying blood into the artery in a second direction which is generally opposite to the insertion direction. | 11-06-2014 |
| 20140358120 | MEDICAL SYSTEM AND CATHETER CONNECTOR APPARATUS - A medical system for connecting a multiple lumen medical catheter to associated medical instrumentation includes a connector member defining a longitudinal axis and having a first end for releasable coupling to the medical catheter and a second end for coupling to medical instrumentation. A mounting segment is adjacent the first end of the connector member. The mounting segment includes first and second mounting elements extending in a general longitudinal direction and arranged in spaced relation, and being adapted for reception within respective lumens of the catheter. The first and second mounting elements define inner opposing surfaces. At least one of the opposing surfaces may have an irregular surface portion dimensioned to engage the septum wall of the catheter to facilitate gripping engagement with the septum wall to assist in coupling of the connector member with the catheter. | 12-04-2014 |
| 20140358121 | PROPHYLACTIC DRESSING AND USE OF SAME IN THE PREVENTION OF INFECTION - Wounds and temporary appliances can be protected against liquid contamination using a prophylactic dressing. The dressing includes a liquid resistant sheet and disposed thereon a first liquid barrier/adhesive strip and a second liquid barrier/adhesive strip wherein the first and second liquid barrier/adhesive strips are concentric; located at or near the periphery of the liquid resistant sheet; and are separated from one another by a gap. Adsorbent's and liquid indicators can be employed within the gap to add further functionality to the dressing. Also disclosed herein is a support useful for stabilizing leads to transcutaneous or percutaneous devices. | 12-04-2014 |
| 20140371715 | SAFETY NEEDLE SYSTEM OPERABLE WITH A MEDICAL DEVICE - A safety needle system operable with a medical device includes: a housing with a needle mount having a needle; and a sheath telescopically engaged with the housing and surrounding the needle such that the sheath operates in a retracted position, in which the sheath exposes the needle, and an extended position, in which the sheath surrounds the needle. The sheath is coupleable to the medical device such that removal of the needle from the medical device draws the sheath over the needle, transitioning the sheath from the retracted position to the extended position. In one embodiment, the system includes a slider engaged with the sheath and/or housing and including a restraint that engages and disengages the sheath to respectively reinforce and weaken the coupling of the sheath and medical device. In another embodiment, the sheath includes a longitudinal track that slidingly engages a setting of the housing between sheath positions. | 12-18-2014 |
| 20150032085 | HEPATIC NEUROMODULATION TO TREAT FATTY LIVER CONDITIONS - According to some embodiments, a method of treating conditions affecting a liver of a subject is provided. The method may include delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery. | 01-29-2015 |
| 20150051583 | SPLIT AND SIDE-PORTED CATHETER DEVICES - A catheter for use in medical applications is disclosed. The catheter comprises tubing with a tip hole at one end and an end portion at the other end. Fluid exits the catheter at the tip hole thereof. One or more alternative fluid pathway(s) are provided on the sidewall of the catheter to permit outflow of fluid medication from the catheter to ensure proper delivery of the medication to the intended target area, particularly when the tip opening is occluded or restricted for any reason. | 02-19-2015 |
| 20150080853 | Aspiration Thrombectomy Catheter System, And Associated Methods - An aspiration thrombectomy catheter system includes an aspirator and an aspiration catheter for insertion in a blood vessel. The catheter has a shaft with a proximal end for connection with the aspirator and a tapering distal end with a tip for insertion in the vessel. A plurality of aspiration ports are arranged in sets along the tapering distal end, for aspirating thrombus from the vessel. At least one aspiration lumens within the shaft conducts thrombus from the vessel, through the aspiration ports, to the aspirator. Variably sized or shaped ports provide differing aspiration vectors for enhanced thrombus removal. The aspiration thrombectomy catheter additionally provides for uniform drug dispersion at a thrombotic area, alone or in combination with aspiration of the thrombus. In the event of an adverse reaction, drug dosage may be easily reduced by aspirating dispersed drugs back into the catheter. | 03-19-2015 |
| 20150100040 | MEDICAL MATERIAL SUPPLY DEVICE - A medical material supply device which can percutaneously supply a material for nerve regeneration that promotes the regeneration of a nerve is insertable into a vessel and includes: a supply section configured to penetrate from an inner wall to an outer wall of the vessel at a predetermined position in the vessel, thereby being able to supply a material for nerve regeneration to the outer wall of the vessel; and an elongated body which is inserted into the vessel, in which the supply section is provided with a linear portion which is provided at the elongated body and is configured to penetrate from the inner wall to the outer wall of the vessel. | 04-09-2015 |
| 20150112304 | APPARATUS HAVING A SELECTIVELY CURVED DISTAL END AND METHODS FOR USE - An apparatus having a distal end that may be selectively bent in situ. The apparatus has a curved configuration and a substantially straightened configuration. First and second tubular components of the apparatus each include a distal portion that is at an acute angle with respect to a longitudinal axis of the apparatus. The second tubular component is rotatably disposed within the first tubular component. In the curved configuration, the distal portions of the first and second tubular components are positioned to extend at substantially the same acute angle with respect to the longitudinal axis of the apparatus. In the substantially straightened configuration, the distal portions of the first and second tubular components are positioned such that the curvatures thereof counterbalance each other. The first and second tubular components may be used in an occlusion bypassing apparatus for re-entering the true lumen of a vessel after subintimally bypassing an occlusion. | 04-23-2015 |
| 20150112305 | FLUID TRANSPORT APPARATUS, FLUID INFUSING APPARATUS, AND TROUBLE DETERMINING METHOD FOR TRANSPORTING TUBE - A fluid transport apparatus includes: a first electrode provided on the insulating transporting tube which constitutes part of a flow channel in which conductive fluid is transported, and configured not to come into contact with the fluid in the flow channel a second electrode configured to come into contact with fluid in the flow channel; and a determining unit connected to the first electrode and the second electrode, and configured to determine a trouble of the transporting tube. Accordingly, the trouble of the transporting tube is determined. | 04-23-2015 |
| 20150119852 | METHOD AND APPARATUS FOR INTRODUCING AN INTRAVENEOUS CATHETER - An improved catheter insertion assembly having a transparent tubular member open at each end; a plunger assembly slidable within the tubular member having a stem portion at a first end; and at least a partially transparent chamber having a needle base and sealing member on a second end of the plunger assembly; an elongated tubular needle embedded within the needle base and extending there from with the needle in fluid communication with the transparent chamber; a catheter assembly, a transparent cannula and a transparent hub attached to the second end with the tubular needle passing longitudinally through the cannula; a fluid passage formed between the needle and the cannula so that when the plunger is retracted a vacuum is established within the fluid passage and blood is visibly drawn through the fluid passage into the transparent cannula and if volume permits, blood then would be visible in the transparent hub, and then if volume permits blood would be visible in the void of the catheter body (barrel) created by pulling the plunger; and wherein the tubular needle is threaded through a lumen of the cannula; and wherein the sealing member provides a sliding seal between the plunger assembly and the transparent tubular member; and wherein, a fluid communication exists through the needle into the flashback chamber of the plunger apparatus and through a porous vent. The distal end of the catheter device described herein has the addition of an external flange and dual plunger paddles which allow dynamic positioning of the fingers and one handed operation. Furthermore these structures are ergonomically associated to maximize finger surface area operation; and wherein the user can change the orientation of the beveled needle. | 04-30-2015 |
| 20150119853 | Convertible Shape Catheter And Method Of Use - A method of controlling and changing the shape of a catheter in situ that includes the use of two nested catheters. The catheters have two different shapes that may add, cancel, or override each other when one catheter is placed within the other. The shape may be changed by advancing or rotating one catheter relative to the other catheter. | 04-30-2015 |
| 20150119854 | Catheter Introducer Including a Valve and Valve Actuator - Tear-away sheath introducers for catheters and methods for making and using such introducers are described. The sheath introducers contain movable valves that are encapsulated in a movable housing that allows the valve to move along the introducer axis. As the movable valve and housing travel along the axis, a portion of the hub protrudes past the valve and is exposed. As well, the sheath introducers can also contain a stationary valve and housing that can be opened to expose a portion of the hub when a conduit penetrates the stationary valve. The conduit can include a one-way, two-way, or other suitable valve actuator that can penetrate and open the valve, yet remain attached to a portion of the introducer when the introducer is split for removal from a patient. In both instances, the protruding portion of the hub contains a friction-free pathway for a catheter into the sheath introducer. | 04-30-2015 |
| 20150141958 | DEVICES AND METHODS FOR VASCULAR ACCESS - A vascular access needle assembly is disclosed. The needle assembly contains a needle and a sheath. The needle has a first part, a second part, and a third part. The needle contains a pointed end configured to penetrate skin of a patient and a sheath slidably and rotatably coupled with the needle. The sheath having one or more irrigation slots configured to transmit a fluid from a fluid source to a vascular region. | 05-21-2015 |
| 20150141959 | METHODS AND SYSTEMS FOR INHIBITING VASCULAR INFLAMMATION - Methods and kits for delivering pharmaceutical agents to the adventitia and other regions outside the external elastic lamina (EEL) surrounding a blood vessel utilize a catheter having a needle. The needle is positioned in up to 5 mm beyond the EEL and delivers an amount of pharmaceutical agent sufficient to circumferentially permeate around the blood vessel and, in many cases, extend longitudinally and radially along the blood vessel. Confirmation that a delivery aperture of the needle lies beyond the EEL may be required before delivering the pharmaceutical agent. In one example, the catheters are used to deliver dexamethasone and other anti-inflammatory agents to the peripheral and other vasculature to treat peripheral vascular disease and other conditions. | 05-21-2015 |
| 20150148778 | Systems And Methods For Performing An Injection - Devices, systems, and methods for performing injections with lowered likelihood of infection include catheters and other injection means with protective coverings. The protective covering can protect the catheter or other injection means before, during, or before and during insertion of the catheter into an insertion site. The protective covering includes two or more parts of interlocking protrusions and channels that allow for sliding motion of the parts relative each other but that resist separation of the parts in the direction perpendicular to the long axis of the two or more parts. | 05-28-2015 |
| 20150148779 | SYSTEM AND METHOD FOR DELIVERING MATERIAL INTO A PATIENT - Apparatus for delivering material into a patient includes a catheter having a proximal end and a distal end. Material, preferably of filamentary or thread form, is fed from a material supply into a Y-fitting having a main branch and a side branch. The side branch is connected to a source of driving fluid able to feed drive fluid under pressure into the material carrier so as to pull material forwardly and out of the distal end of the catheter. The assembly includes an inner cannula within which material is passed from the material source. This increases the speed of delivery of material though the device and reduces the amount of drive fluid which is required. | 05-28-2015 |
| 20150290247 | METHODS FOR REJUVENATING RED BLOOD CELLS - Methods and a system for transfusing blood to a mammalian subject. The method includes obtaining a volume of donated red blood cells (RBCs), adding an enhancement composition to the RBCs to form a treated blood composition, incubating the treated blood composition to form an incubated blood composition, and administering the incubated blood composition to a patient. The system includes a functionally-closed, sterile Y-type tube set. | 10-15-2015 |
| 20150297834 | MIXING NOZZLE - A mixing nozzle includes at least two individual mixing channels dimensioned to create a turbulent flow effect to facilitate dispersion of the components of a medical agent, such as a liquid embolic composition, during delivery, e.g., to vasculature of a subject. In some examples, the mixing nozzle is configured to be mechanically and fluidically connected to a syringe, a catheter, or both the syringe and the catheter. | 10-22-2015 |
| 20150306307 | CANNULA DEPLOYMENT MECHANISM - A cannula insertion device is disclosed. The device includes a needle carriage, a rail device on which the needle carriage is slidable, a yoke having a channel, a linkage connected to the needle carriage and extending into the channel, a torsion spring with one end connected to the linkage, and locking device for locking the torsion spring in tension and maintaining the needle carriage and the linkage in a locked position prior to activation. Upon release of the locking device, the tension of the torsion spring is released, which causes the linkage to move in the channel and slide the needle carriage along the rail device. A catheter carriage may also be provided for actuation by the linkage. | 10-29-2015 |
| 20150306310 | Method for Processing Infusion Data and an Infusion Pump System - A distributed infusion pump system is provided with long-term recording of the type of medication, nutrition or hydration, pump output pressure, corresponding infusion flow, infusion flow resistance, and an automatic or manual alarm in the event that thresholds applied to these parameters or their derivatives are exceeded. | 10-29-2015 |
| 20150306311 | Closed Tip Dynamic Microvalve Protection Device - An endovascular microvalve device for use in a vessel during a therapy procedure includes an outer catheter, an inner catheter displaceable within the outer catheter, and a filter valve coupled to the distal ends of the inner and outer catheters. The valve is constructed of a braid of elongate first filaments coupled together at their proximal ends in a manner that the first filaments are movable relative to each other along their lengths. A filter is provided to the braid formed by electrostatically depositing or spinning polymeric second filaments onto the braided first filaments. The lumen of the inner catheter delivers a therapeutic agent beyond the valve. The device is used to provide a therapy in which a therapeutic agent is infused into an organ. | 10-29-2015 |
| 20150314074 | Apparatus And Methods For Purging Catheter Systems - Apparatus and methods for providing controlled pressure-flow pulses which purge a catheter system with turbulent flow flushing. Accomplishment of such controlled pressure-flow pulses is provided by a variety of inventive devices including a special plunger rod for a conventional syringe, other interactive parts for conventional syringes, an in-line catheter attachable device which automatically generates the controlled pressure-flow pulses and also single pulse, digitally operated devices. | 11-05-2015 |
| 20150320976 | Catheter Connection and Stabilization Device and Methods of Using Same - A device for stabilizing a patient catheter includes a docking pod with a body, an inlet, an outlet, an internal fluid path between the inlet and the outlet, and a securement surface located on an underside of the docking pod. A docking pod adhesive layer located at least partially on the securement surface of the docking pod may secure the docking pod to the patient such that the securement surface and the docking pod adhesive layer form a generally planar or concave surface when secured to the patient. A valve mechanism located within the internal fluid path of the docking pod may control fluid flow through the docking pod. The device may also have a luer connector that is fluidly connected to the outlet of the docking pod and configured to be connected to the catheter. | 11-12-2015 |
| 20150327875 | SYSTEMS AND METHODS FOR REMOVAL OF BLOOD AND THROMBOTIC MATERIAL - A system for aspirating thrombus includes a catheter having a supply lumen having a distal end and an aspiration lumen configured to couple to a vacuum source and having an interior wall surface and an open distal end, an orifice at or near the distal end of the supply lumen, in fluid communication with the interior of the aspiration lumen, the orifice located proximally of the open distal end of the aspiration lumen, wherein the orifice is configured to create a spray pattern that impinges on the interior wall surface of the aspiration lumen when a distal end of the aspiration catheter is immersed within an aqueous environment, and a disposable tubing set having a first conduit configured to couple the supply lumen of the aspiration catheter to a fluid source, and a pump component associated with the first conduit and configured to detachably couple to a drive unit. | 11-19-2015 |
| 20150343131 | DIALYSIS SYSTEM AND METHODS - Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysate solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy. For example, the dialysis systems include disposable cartridge and patient tubing sets that are easily installed on the dialysis system and automatically align the tubing set, sensors, venous drip chamber, and other features with the corresponding components on the dialysis system. Methods of use are also provided, including automated priming sequences, blood return sequences, and dynamic balancing methods for controlling a rate of fluid transfer during different types of dialysis, including hemodialysis, ultrafiltration, and hemodiafiltration. | 12-03-2015 |
| 20150343169 | DEVICES AND METHODS FOR LUNG VOLUME REDUCTION - Methods and devices for treating a lung are disclosed. The method may include deploying a catheter into a blood vessel directing blood towards a portion of the lung, and discharging a media into the blood vessel through the catheter, the media may be configured to at least partially block the flow of blood within the portion of the lung. | 12-03-2015 |
| 20150343175 | Fluid Delivery Catheter with Pressure-Actuating Needle Deployment and Retraction - A fluid delivery catheter that uses micro-needles for fluid delivery though a vessel wall. The catheter may provide fluid delivery therapy for various procedures, such as, for example, delivery of tumescent fluid or renal denervation. The catheter includes an elongate member with deployable and retractable needles disposed about a distal end of the elongate member. The needles may be disposed radially about the distal end and/or along a length of the distal end. | 12-03-2015 |
| 20150374953 | CONTROLLING CATHETER FLOW - A catheter assembly includes an elongate member and a balloon. The elongate member defines at least one lumen and an outer surface. The outer surface defines at least one opening in fluid communication with the at least one lumen. The balloon is disposed within the at least one lumen. The balloon is inflatable such that a portion of the balloon expands from the at least lumen through the at least one opening. The expansion of the balloon increases the flow restriction through the at least one opening compared to the flow restriction through the at least one opening when the balloon is in a deflated condition. Methods for using a catheter assembly to remove occlusive material from a catheter are also described. | 12-31-2015 |
| 20160030730 | TRANSFER DEVICE VALVE - A valve is disclosed, the valve comprising a housing having an first opening and a second opening, and an elastomeric member positioned in the housing, the elastomeric member comprising a thickness, a continuous peripheral wall projecting from the thickness, and a slit extending through the thickness, a continuous portion of the peripheral wall creating a continuous sealable contact with the housing and partitioning the housing into an upper section and a lower section, the elastomeric member configured such that upon creating a pressure differential between the upper section and the lower section of the housing causes either: (i) the peripheral wall to deflect from the housing permitting fluid flow around the elastomeric member; or (ii) the slit to open permitting fluid flow through the elastomeric member. Methods using the valve are also disclosed. | 02-04-2016 |
| 20160074621 | VASCULAR MICROCATHETER - There is provided a microcatheter with a tapering wall thickness shaft having varying stiffness/flexibility along its length from proximal end near the medical practitioner to the distal end near the target site in the patient, such as with at least three segments. The shaft is prepared of a thermoplastic material having varying composition along its length. The distal end may be shaped according to the required use just prior to the medical procedure. The microcatheter is particularly adapted for the delivery of microspheric compositions for treatment of tumors or fibroids by embolization of peripheral blood vessels of the tumor or fibroid. | 03-17-2016 |
| 20160120571 | DEVICES AND SYSTEMS FOR THROMBUS TREATMENT - A thrombus treatment device includes a support wire, a body frame portion that is disposed about an axis defined by the support wire, one or more tethers that each have a first end and a second end, and a filter element extending from the body frame portion. Each of the one or more tethers is attached at its first end to the body frame portion, and at its second end to a collar that couples the second end of each of the multiple tethers to the support wire. When the collar is positioned substantially within a region interior of the body frame portion, a rotational actuation of the support wire causes a swiveling motion of the one or more tethers. | 05-05-2016 |
| 20160121079 | BI-DIRECTIONAL CANNULA - A bi-directional cannula for perfusing blood in two directions. The cannula has a distal opening in fluid communication with a cannula first lumen. The cannula has a secondary opening proximal of the distal opening, and may include a movable tubular extension selectively extendable from the cannula via the secondary opening. The tubular extension may be in fluid connection with the cannula first lumen and/or a cannula second lumen. The tubular extension may have distal and/or side openings, with the openings providing antegrade fluid perfusion. The cannula second lumen may be separate from the first lumen, so that perfusion can be selectively provided to just the cannula distal opening, just the secondary opening/tubular extension, or simultaneously to both the distal opening and secondary opening/tubular extension. | 05-05-2016 |
| 20160129220 | CATHETER DEVICES, SYSTEMS AND METHODS FOR INJECTION OF ADHESIVE MATERIALS - Embodiments relate to a system for providing a first fluid and a second fluid. The system includes a catheter hub, a flexible cover, and a catheter. The flexible cover is configured to attach to the catheter hub and provide a seal therewith. The catheter is configured to be at least partially arranged within the catheter hub and the flexible cover and pass through the seal. The catheter includes a primary lumen and a secondary lumen, wherein the primary lumen is configured to provide the first fluid at a distal end of the catheter, and the secondary lumen is configured to provide the second fluid at each of a plurality of apertures arranged on an outer radial wall of the catheter. | 05-12-2016 |
| 20160136395 | SYSTEMS AND METHODS FOR PROVIDING SECUREMENT AND POSITION VERIFICATION FOR MEDICAL CATHETERS - An antimicrobial, securement, and position verification device for medical catheters is disclosed. A film, medical grade adhesive, and antimicrobial substance disposed on the medical grade adhesive operate in conjunction to secure the device to the patient's skin and to prevent infections. The catheter is secured by guide channels in the foundation and securement cover through the use of one or more adhesives impregnated with antimicrobial substances. The device further comprises catheter position alert media and indicators configured to indicate any unintentional positional changes. | 05-19-2016 |
| 20160151089 | DISTALLY ORIENTED NEEDLE OBTURATOR | 06-02-2016 |
| 20160158499 | Two-Part Multi-Function Vascular Catheter And Integrated Circumferentially Sealing Securement Dressing - A catheter and dressing assembly is disclosed including a dressing having a distal adhesive plate configured for attachment to a skin region surrounding a catheter insertion site to provide a first circumferential seal around the catheter at the insertion site, a dressing body extending from the adhesive plate and configured to surround a catheter segment external to the insertion site and a proximal sealing element. The assembly further includes a two-part catheter having a first distal part consisting of a hub base bonded to a tubular catheter body; and a second proximal interconnector-cap that is adapted to couple to the distal hub base, whereby the attachment of the interconnector-cap to the hub-tubular body portion of the catheter establishes at least one continuous fluid pathway extending from a proximal end of the interconnector-cap to a lumen of the catheter and wherein either the hub base or the interconnector cap further comprises a mating feature for mating to the proximal sealing element of the dressing such that the dressing and interconnector-cap provide a second circumferential seal around the catheter body. | 06-09-2016 |
| 20160175575 | DEVICES, SYSTEMS AND METHODS FOR REMOVAL AND REPLACEMENT OF A CATHETER FOR AN IMPLANTED ACCESS PORT | 06-23-2016 |
| 20160192944 | Venous Insufficiency Treatment Method | 07-07-2016 |
| 20160193390 | Perivascular Delivery System And Method | 07-07-2016 |
| 20160193457 | FLEXIBLE MEMBER FOR RESISTING RETROGRADE FLOW | 07-07-2016 |
| 20160199067 | MEDICAL DEVICE WITH A REMOVABLE LINER | 07-14-2016 |
| 20160250442 | CATHETER | 09-01-2016 |
| 20170232232 | Resource Information Key For An Insertable Medical Device | 08-17-2017 |
| 20190143074 | BI-DIRECTIONAL PERFUSION CANNULA | 05-16-2019 |
| 20220133571 | AUTOMATED INTRAVENOUS FLUID CONTAINER DELIVERY DEVICE AND SYSTEM - A transport device configured to transport an IV product or medication from one location to another in automated fashion. The transport device may comprise a chassis with one or more ports for IV products. A drive mechanism is configured to move the transport device, and instructions for execution can be provided by a controller. Information may be provided to the controller about an IV product, such as its intended destination or use. The controller may also exchange information with a delivery location or device, such as an infusion pump, to verify that the IV product is delivered to the proper destination. The transport device may include a delivery mechanism for off-loading an IV product. The transport device may deliver IV products of various configurations, including configurations in which the product comprises a flexible bag and a container housing for supporting and protecting the fluid bag. | 05-05-2022 |
