Entries |
Document | Title | Date |
20080208162 | Device and Method For Thermophoretic Fluid Delivery - A method and device for thermolphoretic fluid or drug delivery through the creation of a thermal gradient in the skin. The device includes a heat generating mechanism capable of transdermal delivery of a beneficial agent, an insulating portion coupled with the heat generating mechanism, a cold generating mechanism coupled with the insulating portion, and wherein the heat generating mechanism and the cold generating mechanism create a thermal potential across dermal regions. The method includes generating a hot dermal region and transdermally delivering a beneficial agent, insulating, generating a cold dermal region, and creating a thermal potential across the hot dermal region and the cold dermal region. | 08-28-2008 |
20080208163 | Use of Reverse Thermosensitive Polymers to Control Biological Fluid Flow Following a Medical Procedure - One aspect of the present invention relates to a method to control biological fluid flow at a site in a mammal by use of an in situ formed polymer plug. In certain embodiments, the present invention relates to a method to control bleeding following a catheterization procedure, a method to control leakage of cerebral spinal fluid following a lumbar puncture, a method to seal a fistula, or a method to control the flow of serous fluid after a lymphadenectomy. In certain embodiments, the polymer plug is generated in situ by temperature changes, pH changes or ionic interactions. In certain embodiments, the polymer plug comprises at least one optionally purified reverse thermosensitive polymer. | 08-28-2008 |
20080208164 | METHODS FOR THE TREATMENT OF ANAL INCONTINENCE - The present invention relates to methods of preventing or treating anal incontinence comprising injecting muscle-derived cells into a site of interest via an injection device, where the injection site of interest is, or is adjacent to, muscle-tissue providing for anal continence. | 08-28-2008 |
20080208165 | METHODS, SYSTEMS, AND KITS FOR IMPLANTING ARTICLES - Methods, systems, and kits for subcutaneously implanting articles, such as drug inserts and reservoirs. The methods rely on percutaneously forming a tissue tract and radially dilating the tract to a diameter which permits introduction of the article. By fully expanding the lumenal diameter of the tissue tract prior to introduction of the article, damage to the article resulting from passage through a partially expanded tissue tract can be avoided. In the exemplary embodiment, a radially expandable sleeve is first percutaneously introduced to the subcutaneous target site. An assembly of a cannula and dilator is then passed through the sleeve, effecting radial expansion. The dilator is removed and the article is then introduced through a lumen of the cannula. | 08-28-2008 |
20080221548 | Eradication of Pigmentation and Scar Tissue - The invention is a non-surgical method for the eradication of pigmentation and scar tissue from an area of skin. The method comprises repeatedly puncturing the area of skin with an array of needles. As the needles are inserted into the skin, the needles and surface of the skin are washed with a clean solution. As the needles are withdrawn from the skin, the flow of clean solution ceases and the dirty solution, which contains cellular fluids and pigments released by the action of the needles, is removed from the surface. The invention is also a solution, which is used to clean the needles and to aid in destroying the pigment containing cells, and an apparatus, which is especially designed to move the needles into and out of the surface of the skin and to provide synchronization of the motion of the needles and flow of the solution such as to maximize the effectiveness of the method. | 09-11-2008 |
20080221549 | RAPID INJECTION DEVICE - A rapid injection device including a hand-held injection unit having multiple needles to inject at least one subject, and an injection manager to control at least the injection unit according to injection parameters, such as for performing rapid injections by receiving a mode of operation, receiving a dosage amount, receiving a needle extension length, extending a needle the length of the needle extension length out a needle storage unit, and pumping the dosage amount of fluid through the needle. | 09-11-2008 |
20080228164 | Implant delivery system - An embodiment includes a site marker deployment system that includes a deployment device having an inner cannula and a site marker that may be selectively interposed within the inner cannula. The site marker includes at least one generally elongated filament member. The filament member is selectively configurable between a first configuration, where the site marker can not be interposed within the inner cannula, and a second configuration, where the site marker may be interposed within the inner cannula. A portion of the site marker is elastically deformed when the site marker is interposed within the inner cannula. The site marker deployment system also includes a restraining member selectively interposed within the inner cannula and selectively engaging the site marker such that a force exerted on the restraining member may urge the site marker at least partially into the inner cannula. | 09-18-2008 |
20080234655 | Electroporation device and injection apparatus - An apparatus is provided for injecting a fluid into body tissue, the apparatus comprising: a hollow needle; and fluid delivery means, wherein the apparatus is adapted to actuate the fluid delivery means in use so as to automatically inject fluid into body tissue during insertion of the needle into the said body tissue. | 09-25-2008 |
20080234656 | METHOD FOR ALTERING DRUG PHARMACOKINETICS BASED ON MEDICAL DELIVERY PLATFORM - A method for directly delivering whereby a substance is introduced into an intradermal space within mammalian skin which involves administering the substance through at least one small gauge hollow needle having an outlet with an exposed height between 0 and 1 mm. The outlet is inserted into the skin to a depth of between 0.3 mm and 2 mm such that the delivery of the substance occurs at a depth between 0.3 mm and 2 mm. | 09-25-2008 |
20080243101 | ABSORBABLE POLYMER FORMULATIONS - A co-polyester which includes the reaction product of a polycondensation polyester and epsilon-caprolactone, wherein the polycondensation polyester comprises the reaction product of diglycolic acid and/or a derivative thereof and a diol. The co-polyester is injectable and absorbable into animal, such as human, tissue and can be used for facial cosmetic or reconstructive surgery of soft tissue. Another embodiment is directed to a method for preventing adhesion using a co-polyester comprising the reaction product of a polycondensation polyester and epsilon-caprolactone, wherein the polycondensation polyester comprises the reaction product of diglycolic acid and/or a derivative thereof and a diol, and the co-polyester comprises about 40 to 50% by weight of the polycondensation polyester based on the total weight of the co-polyester. | 10-02-2008 |
20080249500 | APPARATUS AND METHOD FOR TREATMENT OF ETHMOIDS - A method of treating diseased ethmoid sinuses in a patient with a therapeutic agent includes providing an injection device comprising an elongate member having a proximal end, a distal tip or end, and a lumen extending between the distal tip and the proximal end, the proximal end being operatively coupled to a source of the therapeutic agent. The distal tip of the injection device is inserted at least partially within an interior portion of an ethmoid air cell. The therapeutic agent is then injected into the interior portion of the ethmoid air cell using the injection device, the therapeutic agent being delivered via the lumen in the elongate member. | 10-09-2008 |
20080249501 | Methods for Simultaneous Injection and Aspiration of Fluids During a Medical Procedure - Methods for simultaneous injection and aspiration of fluids during a medical procedure are disclosed. Embodiments include methods for operating medical devices within the subarachnoid space of the spinal column to gain access to the ventricles of the brain, as well as the surrounding cranial subarachnoid space. A dual lumen constant volume aspiration catheter is disclosed that injects a volume of injectable fluid to break up an obstruction within the brain or cranial subarachnoid space while simultaneously aspirating a same volume of aspirated fluid from the treatment site. Methods hereof include constant volume re-circulation of cerebral spinal fluid to and from a treatment area within one of the brain and the surrounding cranial subarachnoid space, which may be desirable during a ventriculostomy. | 10-09-2008 |
20080249502 | Apparatus and method of safe placement of bulking materials for gastroscopic vagus nerve bulking to reduce appetite and to effect weight loss - An apparatus for grasping the fundal mucosa and method for delivery of and safe placement of a tissue bulking agent adjacent to the right and left vagus nerve trunk in the lesser curvature of the of the stomach or at the gastroesophageal junction to compress the vagus nerve trunks that control both electrical stimulation of the gastric ghrelin cells, and the parastolic muscular tone of the smooth muscles of the stomach to effect appetite and effect weight loss. | 10-09-2008 |
20080249503 | METHODS AND DEVICES FOR LUNG TREATMENT - A method of treating a lung comprises deploying a delivery catheter through a bronchial tree into a targeted lung region and delivering a fibrinogen suspension through the delivery catheter so that the fibrinogen suspension exits the distal end of the delivery catheter into the targeted lung region. Thrombin is also delivered through the delivery catheter so that the thrombin exits the distal end of the delivery catheter into the targeted lung region. The lung is promoted to collapse. | 10-09-2008 |
20080255537 | BIOCOMPATIBLE NANOPARTICLE COMPOSITIONS AND METHODS - Various compositions, methods, and devices are provided that use fluorescent nanoparticles, which can function as markers, indicators, and light sources. The fluorescent nanoparticles can be formed from a fluorophore core surrounded by a biocompatible shell, such as a silica shell. In one embodiment, the fluorescent nanoparticles can be delivered to tissue to mark the tissue, enable identification and location of the tissue, and/or illuminate an area surrounding the tissue. In another embodiment, the fluorescent nanoparticles can be used on a device or implant to locate the device or implant in the body, indicate an orientation of the device or implant, and/or illuminate an area surrounding the device or implant. The fluorescent nanoparticles can also be used to provide a therapeutic effect. | 10-16-2008 |
20080269715 | Use of an Adhesive as an Intestinal Barrier for Bariatrics - An apparatus for achieving weight loss in a patient is disclosed. The apparatus has a barrier material and an applicator for dispensing the barrier material about the intestine. An injector is used to place the barrier material to block nutrient transfer from the intestine into the blood stream. The barrier material is a polymerizable adhesive that can be injected interstitially between layers of the intestine, or injected into vascular structures to partially block the flow of blood to the nutrient absorbing layers. | 10-30-2008 |
20080269716 | MEDICAL DEVICE IMPLANTATION - The disclosure is directed to a method for implanting a medical device proximate to a target tissue site within an occipital region of a patient, such as proximate to an occipital nerve or a trigeminal nerve. The method comprises introducing an implant tool into a patient to define an insertion path to the target tissue site. The implant tool includes a shape memory cannula and a malleable needle at least partially disposed within an inner lumen of the cannula. The shape of the needle may be changed to accommodate different anatomical structures/features of the patient. Upon withdrawal of the needle from the cannula, the cannula may change shape, thereby changing the shape of the insertion path. | 10-30-2008 |
20080269717 | Method of deformity correction in a spine using injectable materials - A method is disclosed for increasing the stiffness of an intervertebral disc between vertebral bodies. The method includes providing a syringe with a needle approximately in the range of 16 to 25 gauge; providing a material having a first stage with a first viscosity adapted to flow through the needle, the material having a second stage with a second viscosity greater than the first viscosity, the second stage material having a stiffness in a range of 1.0-5.0 MPa; testing the annulus fibrosus of the disc to ensure that the annulus fibrosus has sufficient continuity so as to retain the first flowable stage material when subsequently injected into the disc; inserting the needle into the annulus fibrosus; injecting the first stage material into the disc; and permitting the first stage material to become the second stage material so as to form a load bearing implant in the disc. | 10-30-2008 |
20080269718 | Method for pressure mediated selective delivery of therapeutic substances and cannula - Methods and devices are disclosed for selective delivery of therapeutic substances to specific histologic or microanatomic areas of organs. Introduction of the therapeutic substance into a hollow organ space (such as an hepatobiliary duct or the gallbladder lumen) at a controlled pressure, volume or rate allows the substance to reach a predetermined cellular layer (such as the ephithelium or sub-epithelial space). The volume or flow rate of the substance can be controlled so that the intralumenal pressure reaches a predetermined threshold level beyond which subsequent subepithelial delivery of the substance occurs. Alternatively, a lower pressure is selected that does not exceed the threshold level, so that delivery occurs substantially only to the epithelial layer. Such site specific delivery of therapeutic agents permits localized delivery of substances (for example to the interstitial tissue of an organ) in concentrations that may otherwise produce systemic toxicity. Occlusion of venous or lymphatic drainage from the organ can also help prevent systemic administration of therapeutic substances, and increase selective delivery to superficial epithelial cellular layers. Delivery of genetic vectors can also be better targeted to cells where gene expression is desired. The access device comprises a cannula with a wall piercing tracar within the lumen. Two axially spaced inflatable balloons engage the wall securing the cannula and sealing the puncture site. A catheter equipped with an occlusion balloon is guided through the cannula to the location where the therapeutic substance is to be delivered. | 10-30-2008 |
20080275424 | METHODS AND DEVICES FOR TREATMENT OF OBESITY - The present invention provides methods and systems for treating obesity by creating an interruption of the vagal nerve, preferably in the region of the esophagus, by minimally or noninvasive means. | 11-06-2008 |
20080275425 | METHOD OF CONTROLLING A MEDICATION DELIVERY SYSTEM WITH A REMOVABLE LABEL CONTAINING INSTRUCTIONS FOR SETTING MEDICATION DELIVERY RATE OVERLYING A SECOND LABEL WITH PATIENT INSTRUCTIONS - A method of controlling a medication delivery system is used to deliver medication to a patient. The system includes an electronic controller, at least one control button, a patient label, and a removable overlay label disposed on top of the patient label for controlling an amount of the medication to be delivered to the patient. The method comprises the steps of selecting the amount of the medication in accordance with a first set of explanatory indicia on the removable overlay label; locking the system such that the selected amount of the medication to be delivered to the patient is unable to be modified; removing the removable overlay label to reveal the patient label; and operating the system in accordance with a second set of explanatory indicia on the patient label. | 11-06-2008 |
20080287908 | Ethmoidotomy System and Implantable Spacer Devices Having Therapeutic Substance Delivery Capability for Treatment of Paranasal Sinusitis - Substance delivering spacer devices may comprise expandable reservoirs that are implantable in paranasal sinuses and other cavities, openings and passageways of the body to maintain patency and to provide sustained local delivery of a therapeutic or diagnostic substance. Also provided are sinus penetrator devices and systems for performing ethmoidotomy procedures or for creating other openings in the walls of paranasal sinuses or other anatomical structures. | 11-20-2008 |
20080287909 | METHOD AND APPARATUS FOR INTRA-CHAMBER NEEDLE INJECTION TREATMENT - A method is disclosed that enables intra-chamber needle injection treatment using a navigable interventional device. The method includes navigation steps to systematically inject cells, drugs, or other agents in diagnostically identified target tissues, such as ischemic heart wall tissues. Magnetic navigation of a specifically designed needle catheter permits safe access to remote structures of the heart and depth-adaptable needle injections. | 11-20-2008 |
20080294142 | Removable Controller for an Infusion Pump - Some embodiments of an infusion pump system includes a controller device that is configured to removably attach to a pump device in a manner that provides a secure fitting, an overall compact size, and a reliable electrical connection. In particular embodiments, the controller device can be secured to the pump device in a generally side-by-side arrangement. The compact size can enhance the discreteness and portability of the infusion pump system. | 11-27-2008 |
20080294143 | BODY-INSERTABLE DEVICE AND LIQUID MEDICINE INJECTION METHOD - A body-insertable device is introduced into a desired part in a body for injecting a liquid medicine stored in a casing into the desired part. The body-insertable device includes a projecting portion which projects an injection needle injecting the liquid medicine toward the desired part; a detecting unit which detects a position relation between a biological tissue surface in the desired part and the injection needle; and a control unit. The control unit controls an amount of projection of the injection needle according to the position relation detected by the detecting unit, and controls a puncture depth of the injection needle from the biological tissue surface. | 11-27-2008 |
20080312635 | Chemical Applicator - The present invention relates to a device and method for a chemical applicator used applying chemicals to Irving organism's internal tissue, including the internal tissue of plants and animals, for organisms which reside in mediums such as land, air or water. The device of the present invention is predicated, in part, on the piercing elements being engageable with the chemical reservoir in order to effect the coating of the piercing elements with the chemical. Once coated, these piercing elements are then used to pierce the living organism's tissue such as plant tissue to deliver the chemical. | 12-18-2008 |
20080319413 | PERCUTANEOUS ARRAY DELIVERY SYSTEM - A system for treating tissue includes a cannula having a proximal end, a distal end, and a lumen extending between the proximal and the distal ends, and an array of delivery tubes at least partially disposed within the lumen, each of the delivery tube having a lumen, wherein each of the delivery tubes is slidable relative to the cannula, and has a first configuration when inside the lumen, and a second configuration when outside the lumen. A system for treating tissue includes a treatment device having a distal end, and an indexing device for controlling a longitudinal position of the distal end of the treatment device relative to a target tissue region, the indexing device having a tubular portion for receiving the treatment device. | 12-25-2008 |
20080319414 | Insertion device - An insertion apparatus and a method for use with a device for delivery of a therapeutic fluid into a body of a patient and/or for sensing of a bodily analyte are disclosed. The apparatus includes a housing adapted for loading therein at least one cannula cartridge unit having a protective member. The protective member accommodates at least one penetrating cartridge having a subcutaneously insertable element and a penetrating member. The apparatus includes a displacement mechanism capable of protracting the penetrating cartridge towards the body of the patient, where protraction of the penetrating cartridge results in insertion of the subcutaneously insertable element into the body of the patient. | 12-25-2008 |
20090012494 | INTRADERMAL DELIVERY OF BIOLOGICAL AGENTS - The present invention relates to methods for intradermally delivering one or more biologically active agents such as vaccines and therapeutic agents into the dermis layer of the skin of a subject to obtain systemic delivery or an immune response using a microneedle drug delivery device containing the agent to be delivered. The methods employ a microneedle device with a row of hollow microneedles. The microneedles penetrate the skin of the subject and assume an anchored state in which the microneedles are anchored in the skin and project laterally from the device. A pivotal motion is then performed with the device so that the skin in which the microneedles are engaged is lifted above the initial plane of the surface of the skin while the biologically active agent is delivered. The methods of the invention elicit increased humoral and/or cellular response as compared to conventional vaccine delivery routes, facilitating dose sparing. | 01-08-2009 |
20090018522 | TISSUE MODIFICATION BY TARGETED DELIVERY OF HEAT - A method for manipulating a tissue by targeted delivery of heat by heating a liquid contained in an injecting means to a predetermined temperature level and injecting a predetermined volume of said heated liquid into a predetermined depth of the tissue through a needle attached to the injecting means, to thereby manipulate the tissue in the injected area. An apparatus adapted for manipulating a tissue by targeted delivery of heat having a heating means adapted to heat a liquid contained in an injecting means to a predetermined temperature level; an injecting means adapted to contain liquid to be injected said tissue and to inject a predetermined volume of said liquid into a predetermined depth of the tissue through a needle; a temperature sensor adapted to identify the temperature level of the liquid contained in the injecting means and to produce a signal indicating said temperature level; a controller adapted to monitor the sensor signal and to activate or deactivate said heating means and an electromechanical element according to the temperature sensed, and an electromechanical element either integrated or non-integrated to the apparatus that is adapted to allow the injection of the heated liquid. | 01-15-2009 |
20090018523 | DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS - Devices, systems and methods for compressing, cutting, incising, reconfiguring, remodeling, attaching, repositioning, supporting, dislocating or altering the composition of tissues or anatomical structures to alter their positional or force relationship to other tissues or anatomical structures. In some applications, the invention may be used to used to improve patency or fluid flow through a body lumen or cavity (e.g., to limit constriction of the urethra by an enlarged prostate gland). | 01-15-2009 |
20090018524 | EXPANDABLE DELIVERY DEVICE - An expandable drug delivery device that can be implanted or otherwise delivered in and/or adjacent to a bone and/or soft tissue (e.g., connective tissue) for orthopedic applications is disclosed. Devices and methods are described herein for delivering agents for orthopedic and other uses. In particular such devices and methods can be useful for delivering agents to heal damaged tissue or prior to more invasive and traumatic orthopedic procedures. | 01-15-2009 |
20090030399 | Drug Delivery Device and Method - The present invention is directed to a medical device and method for delivering a drug. The medical device includes a deformable body configured to be implanted between a first vertebra and a second vertebra for providing shock absorption and stabilization of the vertebras. The deformable body comprises an impermeable inner layer forming an interior volume and an outer layer at least a portion of which is permeable. The outer layer is at least partially outside the inner layer and forms an exterior volume between the inner and outer layers. The medical device further includes a drug reservoir connected to the deformable body and in fluid communication with the exterior volume. The medical device is capable of delivering the drug from the reservoir into the exterior volume and releasing the drug through the permeable portion of the outer layer. | 01-29-2009 |
20090036868 | Spring Driven Ophthalmic Injection Device with Safety Actuator Lockout Feature - An ophthalmic injection device includes a dispensing chamber housing with an inner surface that partially defines a dispensing chamber for holding a substance, a plunger fluidly sealed to the interior surface of the dispensing chamber housing, and a needle fluidly coupled to the dispensing chamber. A temperature control device partially surrounds the dispensing chamber housing and alters a temperature of the substance. A piston is coupled to the plunger at one end and to a spring at the other end. The spring provides a force to drive the piston and the plunger. An actuator is coupled to the lockout bar with which a button is configured to interface. The actuator moves the lockout bar when the substance reaches a temperature, thereby allowing the button to be activated so that the spring provides the force to drive the plunger. An incorporated stop whose measurements may vary allow the expelled dosage to vary accordingly. | 02-05-2009 |
20090036869 | CANNULA SYSTEM - The present disclosure provides a cannula useful for introducing a thermally responsive polymer in situ. In embodiments, the cannula possesses more than one cannula, with the thermally responsive polymer introduced in one cannula, and a material such as a coolant in a second cannula which prevents premature gelling of the thermally responsive polymer. | 02-05-2009 |
20090036870 | INFUSION MEDIUM DELIVERY DEVICE AND METHOD WITH DRIVE DEVICE FOR DRIVING PLUNGER IN RESERVOIR - A delivery device includes first and second housing portions that selectively engage and disengage. A reservoir on one housing portion operatively engages a drive device and/or a needle inserting device on the other housing portion. Upon proper engagement of the housing portions, the reservoir operatively couples to the drive device and/or the needle inserting device. A first magnet on the first housing portion and a second magnet (or a magnetically-attractive material) on the second housing portion are positioned to magnetically interact with each other, upon operative engagement of the housing portions. A third magnet on the second housing portion may be opposed to the first magnet to help align the housing portions for connection. A magnet-responsive device may be on one or both housing portions to detect alignment and/or connection of the housing portions. | 02-05-2009 |
20090043278 | Body-insertable apparatus - A body-insertable apparatus that can reduce the apparatus size and perform projection operation of an injection needle in a power saving manner is provided. A body-insertable apparatus | 02-12-2009 |
20090043279 | MICRONEEDLE ARRAYS FORMED FROM POLYMER FILMS - The present invention provides for transdermal delivery devices having microneedle arrays, as well as methods for their manufacture and use. In one embodiment, a transdermal delivery device is provided. The transdermal delivery device includes a polymer layer which has microneedles projecting from one of its surfaces. The microneedles are compositionally homogenous with the polymer base layer. | 02-12-2009 |
20090043280 | Vaccine Delivery Service - The present invention relates to novel methods of vaccination and vaccine delivery. In particular, the invention relates to methods of vaccination and pre-filled vaccine delivery devices designed to deliver the vaccine into the dermis of an individual | 02-12-2009 |
20090048575 | TROCAR WITH OBTURATOR HAVING LONGITUDINAL THROUGH HOLES FOR GUIDING WIRES - Surgical apparatus includes a trocar and obturator. The trocar has a hollow cylindrical body with a handle at the proximal end thereof. The obturator has a solid cylindrical body with a handle at the proximal end thereof. A central through hole is provided extending through the body and a slot is provided in the circumference of the body, extending parallel to the hole. Guide wires can selectively extend through either the central hole or along the slot. | 02-19-2009 |
20090054866 | Transcutaneous Device Assembly - A medical device is provided comprising a cannula having a distal portion adapted to be arranged through the skin of the subject, and an outer needle arranged coaxially with and being axially moveable relative to the cannula, the needle comprising a pointed distal end, wherein the device is adapted for advancing the cannula with the distal end of the needle projecting there from through the dermis of the subject, and subsequently retract the needle. | 02-26-2009 |
20090054867 | Device for Administering of Medication in Fluid Form - An infusion device for continuously infusion of medication is disclosed, in which infusion is controlled over two separate fluid communications. The infusion is in each fluid communication controlled by restricting means and valve means, and one of the fluid communications further contains a holding device for bolus rate of infusion for a short period. The device comprises a flow regulating device comprising a passage defined by at least a fact element is a primary deformable element adapted to be elastically deformed so as to change the cross sectional area of the passage. Furthermore the device comprises a container for storage and supply of a medication in fluid form, said container comprising a first and a second chamber being arranged relatively to each other so that when volume of the first chamber increases the volume of the second chamber decreases. | 02-26-2009 |
20090062768 | Systems and methods for delivering medication - Systems and methods for delivering medication to a patient are disclosed. The system has a reservoir, a sequencer/monitor, and an insertion set which are mated during use. | 03-05-2009 |
20090069788 | System And Method For Delivering Fluid Into Flexible Biological Barrier - A system and method for delivering fluid into a flexible biological barrier employs a microneedle structure wherein a final position of microneedles ( | 03-12-2009 |
20090082754 | Cannula implantation instrument - A cannula implantation instrument for use with the delivery of guide wire based implants includes a handle having an open slot for receiving a guide wire and a cavity for receiving an implant pre-mounted on the guide wire, a cannula having an open slot for also receiving a guide wire and a sharpened tip for introducing the cannula and guide wire simultaneously into the vas deferens of a patient, and a guide wire on which an intra vas implant is pre-mounted. The instrument further includes a safety clip on the handle that secures the guide wire and/or implant to the handle until released by a physician. The cannula implantation instrument may be ergonomically formed to provide comfort and ease while being handled by the physician. | 03-26-2009 |
20090088722 | Straight Insertion Safety Infusion Set - An infusion set assembly comprising a cannula housing having a base surface and a septum housing adapted to be pivotally attached to the cannula housing for movement between a position where an axis thereof is substantially perpendicular to the base surface and a position where the axis is substantially parallel to the base surface. The infusion set assembly further comprises an insertion needle assembly including an insertion needle and a cannula supported by the needle assembly with a tip of the insertion needle extending from a distal end of the cannula. An insertion guide housing is configured to support the insertion needle assembly with the needle substantially perpendicular to the base surface and adapted for movement between a position where the needle tip and cannula distal end are spaced from the base surface and a position where the needle tip and cannula distal end extend beyond the base surface. | 04-02-2009 |
20090093787 | ERGONOMIC SYRINGE - The present embodiments relate to devices and methods for injection. More specifically, the devices and methods provide an ergonomic aspect. In some embodiments, the devices and methods are especially useful in the administration of low volumes of dermal fillers to a subject. | 04-09-2009 |
20090093788 | Thermal Coefficient Driven Drug Pellet Size For Ophthalmic Injection - A method of injecting a mixture into an eye includes: providing the mixture in a dispensing chamber with an air gap located between the mixture and an interior surface of a dispensing chamber housing, when the mixture and dispensing chamber housing are near room temperature; bringing the dispensing chamber housing and mixture to a temperature range at which the mixture expands and is in a more liquid state; maintaining air in a needle after the mixture expands and prior to an injection; and injecting the air in the needle and the mixture into the eye. | 04-09-2009 |
20090093789 | Method of Delivering A Rate And Temperature - Dependent Substance Into The Eye - A method of injecting a mixture into an eye includes: providing the mixture in a dispensing chamber with an air gap located between the mixture and an interior surface of a dispensing chamber housing, when the mixture and dispensing chamber housing are near room temperature; bringing the dispensing chamber housing and mixture to a temperature range, other than near room temperature, at which the mixture expands and is in a more liquid state; maintaining air in a needle after the mixture expands and prior to an injection; selecting a drug release rate; and injecting the mixture so as to form a shape with a surface area that results in the selected drug release rate. | 04-09-2009 |
20090093790 | METHOD OF FLUID DELIVERY AND CATHETERS FOR USE WITH SAME - A pain management system for the infusion of drug to a wound site includes a pump connected to medical tubing which is connected to an improved infusion catheter for providing uniform delivery of fluid throughout an anatomical region. The infusion catheter is inserted into the body of a patient at a pierce site, spaced from an incision site, and extended to the wound site. The pump causes the drug to flow through the medical tubing, through the infusion catheter and to the wound site. One method by which the infusion catheter is advanced to the wound site includes a guide needle that is placed within an introducer tubing. The needle is pierced through the patient's skin, after which the guide needle is withdrawn and discarded, leaving the introducer tubing in place partially under the patient's skin. The infusion catheter is then threaded through the introducer tubing and advanced to the wound site. The introducer tubing is then withdrawn and the infusion catheter remains in place to provide drug to the wound site. The introducer tubing is preferably peeled off of the infusion catheter and discarded. In accordance with one embodiment of the catheter, the catheter comprises an elongated tube with a plurality of exit holes along an infusion section of the catheter, and an elongated flexible porous member residing within the tube and forming an annular space between the tube and the member. In accordance with other embodiments, the catheter includes a tube having a plurality of exit holes in a side wall of the tube. The exit holes may combine to form a flow-restricting orifice of the catheter. Advantageously, fluid within the catheter flows through all of the exit holes, resulting in uniform distribution of fluid within an anatomical region. | 04-09-2009 |
20090099544 | METHODS AND SYSTEMS FOR CONTROLLED DEPLOYMENT OF NEEDLES IN TISSUE - Needles are deployed in tissue under direct ultrasonic or other imaging. To aid in deploying the needle, a visual needle guide is projected on to the image prior to needle deployment. Once the needle guide is properly aligned, the needle can be deployed. After needle deployment, a safety boundary and treatment region are projected on to the screen. After confirming that the safety boundary and treatment regions are sufficient, the patient can be treated using the needle. | 04-16-2009 |
20090099545 | Self-contained portable apparatus for administration of a drug solution - A self-contained portable apparatus for administration of a drug solution is disclosed, comprising: a housing having an enclosure for receiving a flexible pouch containing a drug solution, the output of which is connectable to a conduit for delivering said drug solution to a recipient. A pressurization system is arranged for providing a constant and controllable gas pressure to the housing, wherein a controllable pressure is obtained for a controllable delivery of the drug solution. The pressurization system comprises: a pressure source for delivering positive pressure gas; a pressure accumulation tank connected to said source and to said second chamber, arranged to provide a positive pressure reservoir; a one-way valve arranged between said pressure source and said pressure accumulation tank, enabling gas to flow solely in the direction from the pressure source to the pressure accumulation tank; and a mechanical pressure regulator arranged between said pressure accumulation tank and said housing. Hereby, an extremely stable and well controllable output pressure and output flow is obtainable. | 04-16-2009 |
20090112180 | Method for Inserting a Medical Device Flexible Conduit into a User's Target Site - A method for inserting a medical device flexible conduit into a user's target site includes adhering a medical device to a user with the medical device including a medical device flexible conduit and an insertion mechanism. Moreover, the medical device flexible conduit has an elongated Nitinol strip with a distal end, a proximal end, a longitudinal axis running from the distal end to the proximal end, a sharp head extending from the distal end, and a channel etched therein. In addition, the channel is dispositioned along the longitudinal axis. The medical device flexible conduit also includes a flexible tube at least partially jacketing the elongated Nitinol strip between the distal end and the proximal end, the channel and flexible tube defining a conduit. The insertion mechanism is configured to insert a portion of the flexible conduit including the sharp head into a user's target site such that the conduit provides fluid communication to the target site. The method also includes inserting the medical device flexible conduit into the user's target site. | 04-30-2009 |
20090112181 | Device and method for delivering or withdrawing a substance through the skin - An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. A device includes a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid. | 04-30-2009 |
20090118698 | DEVICE AND METHOD FOR APPLYING AN ACTIVE INGREDIENT TO THE SKIN - The invention relates to a device and a process for introducing an active ingredient into the skin. The device comprises a roller that is mounted to rotate around the longitudinal axis thereof and on whose outside peripheral surface a number of needles project radially outward. After the active ingredient has been applied on the skin, the roller rolls over the skin. In this case, the needles penetrate the skin and open up fine channels there, through which the active ingredient penetrates through the epidermis up to the dermis. | 05-07-2009 |
20090118699 | Systems and methods for treating obesity and other gastrointestinal conditions - Systems and methods affect tightening of the pyloric sphincter and/or serve to mediate or moderate receptive relaxation of muscles in the stomach, to treat or mitigate various physiologic conditions, such as obesity, biliary reflex, GERD, and/or Barrett's esophagus. The systems and methods may be used as either a primary treatment modality, or applied as a supplementary treatment before, during or after a primary intervention. | 05-07-2009 |
20090124995 | Backer Plate Adapter for a Syringe Plunger - A backer plate adapter ( | 05-14-2009 |
20090124996 | APPARATUS AND METHODS FOR INJECTING HIGH VISCOSITY DERMAL FILLERS - A method includes inserting a distal end portion of a needle of a medical injector into a skin of a body. An energy source operatively coupled to the medical injector is actuated such that a dermal filler is conveyed from the medical injector into the skin through the distal end portion of the needle. The distal end portion of the needle is moved within the skin during the actuating. | 05-14-2009 |
20090124997 | METHODS AND DEVICES FOR IMPROVING DELIVERY OF A SUBSTANCE TO SKIN - A method of delivery of a substance to a human subject's skin comprising deposition into a specific compartment of the skin, wherein the delivery occurs at a controlled rate and pressure. The methods of the invention provide accurate deposition of s pre-selected volume of the substance, e.g., greater than 90% of the pre-selected volume. The methods of the invention encompass varying one or more parameters including but not limited to configurations of the delivery device, volume, pressure, and flow rate of delivery, to enhance the efficacy of delivery of the substance to the human skin. Substances delivered in accordance with the methods of the invention result in a more efficacious deposition of the substance into the targeted compartment, improved delivery performance, i.e., completeness of delivery as measured by quantification of the substance not delivered or the amount of the substance leaked out from the injection site, and enhanced safety as measured by the occurrence of minimal adverse cutaneous events at the site of injection. | 05-14-2009 |
20090124998 | METHOD FOR DELIVERING THERAPEUTIC OR DIAGNOSTIC AGENTS - An agent delivery device includes an inner tubular body having a proximal end, a sharpened distal end, a delivery lumen extending therebetween, and one or more outlet ports on the distal end communicating with the delivery lumen. The device also includes one or more seals sealing the one or more outlet ports, the one or more seals capable of being melted to allow a fluid to be delivered from the delivery lumen through the one or more outlet ports. The agent delivery device may further include a monopolar or bipolar electrode and/or a radio-opaque marker carried at the distal end of the device. The inner tubular body can be made from a conductive material to thereby allow the inner tubular body to function as an electrode. | 05-14-2009 |
20090131907 | Endoscopic Cardiac Surgery - Apparatus and surgical methods establish temporary suction attachment to a target site on the surface of a bodily organ for enhancing accurate placement of a surgical instrument maintained in alignment with the suction attachment. A suction port on the distal end of a supporting cannula provides suction attachment to facilitate accurate positioning of a needle for injection penetration of tissue at the target site on the moving surface of a beating heart. Force applied via the suction attachment to the surface of the heart promotes perpendicular orientation of the surface of the myocardium for enhanced accuracy of placement of a surgical instrument thereon. A hollow needle and a supporting channel therefor, each include a slot along an outer wall between ends thereof, are selectably rotatable to align the slots for releasing a cardiac lead from within the needle through the aligned slots. | 05-21-2009 |
20090143762 | Methods and Compositions for Enhancing the Viability Of Microneedle Pores - Described herein is a method of transdermally administering one or more pharmaceutically active agents to a mammal. The method comprises administering one or more active pharmaceutical agents to the skin of the subject, in conjunction with microneedles and one or more COX inhibitors, whereby the COX inhibitors facilitate the absorption of the active pharmaceutical agents by prolonging the pore opening created by the application of the microneedle. | 06-04-2009 |
20090143763 | ROTATABLE INFUSION SET - An arrangement for introducing a liquid into the body of a patient or for withdrawing a liquid from the body of a patient, including a first structural part carrying a cannula for positioning in the body of the patient, and a second structural part with a connection port for detachably coupling a conduit for supplying or withdrawing a liquid, wherein the first and second structural parts are connected, can be rotated relative to each another and in relative rotational positions form a channel for introducing a liquid from the conduit to the cannula or for withdrawing a liquid from the cannula to the conduit, and whereby movement of the conduit for coupling and uncoupling is transverse to the longitudinal axis of the cannula. | 06-04-2009 |
20090149830 | Intelligent needle technology for acupuncture and injection of cosmetic preparations subcutaneously - Intelligent needles comprise a needle for insertion into the skin to deposit a substance that causes plumping of the skin. The penetration depth of the needle may be adjusted automatically in conjunction with a sensor mechanism that determines a depth the needle can penetrate without contacting blood vessels. Methods of making and using the same for acupuncture and subcutaneous injection are also provided. | 06-11-2009 |
20090157041 | Microneedel-based pen device for drug delivery and method for using same - A system and method is provided for an injectable substance delivery pen comprising a microneedle hub assembly removably engaged with a pen device body which includes a cartridge, a plunger, and a drive mechanism. The hub assembly includes at least one microneedle for intradermal or shallow subcutaneous injection of the contents of the cartridge. The cartridge, plunger and drive mechanism components of the pen body are fabricated of non-compliant and non-compressible materials to allow effective communication of the cartridge contents via the microneedle patient interface. | 06-18-2009 |
20090171314 | MOLDED ARTICLES COMPRISING MICRONEEDLE ARRAYS - A molded article comprising at least one chain of microneedle arrays wherein adjacent arrays in the chain are interconnected by integrally formed runners. Such a molded article may further comprise two or more chains of microneedle arrays, wherein adjacent chains are interconnected to each other by integrally formed runners. Also, methods of making molded articles and positioning them for delivery to a patient. | 07-02-2009 |
20090177182 | Glass Drug Chamber For Automated Ophthalmic Injection Device - A dispensing assembly has a glass tube assembly, a chamber housing, a needle, and a temperature control device. The glass tube assembly includes a glass tube with inner and outer surfaces and distal and proximal ends. A plunger is fluidly sealed to the inner surface of the glass tube at the proximal end, and a seal is located at the distal end of the glass tube. The chamber housing has an inner surface and an outer surface. The inner surface partially defines a chamber for receiving the glass tube assembly. The needle has sharp distal and proximal ends, traverses the chamber housing, and is fluidly coupled to the chamber. The temperature control device at least partially surrounds the chamber housing. The proximal end of the needle is arranged to puncture the seal when the glass tube assembly is pressed against the proximal end of the needle. | 07-09-2009 |
20090177183 | CELL DELIVERY CATHETERS WITH DISTAL TIP HIGH FIDELITY SENSORS - The present invention relates to over the wire cell delivery catheters with high fidelity sensors at their distal end. These catheters are comprised of flow rate sensors and/or pressure transducer sensors. These catheters can also be comprised of occlusion balloons. The catheters of the present invention allow for administration of the highest and safest dose of therapeutic agents, e.g., adipose derived regenerative cells, on an individualized basis. | 07-09-2009 |
20090177184 | METHOD AND APPARATUS FOR IMPROVING VENOUS ACCESS - Embodiments of the invention include a method and a device for increasing vasodilatation and/or controlling the temperature of a mammal by applying a desired vacuum pressure to the skin of the extremity of a mammal. In some cases it is also desirable to provide heat to regions of the extremity of the mammal to further dilate the veins or arteries in the patient. In some cases it is also desirable to apply a contact pressure to regions of the extremity of the mammal to improve perfusion of these regions. In one embodiment, the device includes a device that is adapted to rigidly enclose a portion of an extremity of the mammal therein so that a sub-atmospheric pressure can be applied to the mammal's extremity, which is further discussed below. | 07-09-2009 |
20090187160 | METHODS AND DEVICES FOR DELIVERING AGENTS ACROSS BIOLOGICAL BARRIERS - The invention provides for microneedle devices for delivering agents across biological barriers. The microneedles include agent reservoirs integrated into the bodies of the microneedles, themselves. | 07-23-2009 |
20090192486 | AUTOMATIC INJECTOR WITH ANTI-CORING NEEDLE - In one embodiment, an automatic injector comprises a cartridge adapted to contain a charge of medicament, a seal structure disposed toward a forward end of the cartridge, a plunger normally disposed in a generally rearward end of the cartridge and movable through the cartridge toward a generally forward end thereof in response to an actuating procedure. The movable plunger rearwardly confines the medicament within the cartridge. A needle normally disposed in communication with the medicament container provides a passage in which the medicament is released into an individual's flesh in response to an actuating procedure projecting the needle into the flesh of the individual. The cartridge having an increased friction region so as to slow the motion of the plunger when the forward end of the needle travels through the seal in order to eliminate coring. | 07-30-2009 |
20090192487 | System and Method for Intracranial Implantation of Therapeutic or Diagnostic Agents - A system and related method for delivering the anti-tumoral agent carmustine or other types of diagnostic or therapeutic agents into the brain of a patient with a brain tumor includes an insertion device, a skull mount, and a reformulated geometry of the carmustine compound (or other material) optimized for use in the insertion device and for maximized biodegradation time. The insertion device may be front loaded with the carmustine material (or other material) and inserted through the mount on a skull, to the location of the brain tumor, where the carmustine (or other material) is then released. It should be appreciated that the diagnostic and/or therapeutic system and related method thereof are not necessarily limited to the brain of a subject. It may also be used in the organ structures or tubular structures, as well as portions and locations thereof. | 07-30-2009 |
20090192488 | SINUS DELIVERY OF SUSTAINED RELEASE THERAPEUTICS - The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers. | 07-30-2009 |
20090192489 | SINUS DELIVERY OF SUSTAINED RELEASE THERAPEUTICS - The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers. | 07-30-2009 |
20090192490 | SINUS DELIVERY OF SUSTAINED RELEASE THERAPEUTICS - The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers. | 07-30-2009 |
20090192491 | SINUS DELIVERY OF SUSTAINED RELEASE THERAPEUTICS - The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers. | 07-30-2009 |
20090192492 | SINUS DELIVERY OF SUSTAINED RELEASE THERAPEUTICS - The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers. | 07-30-2009 |
20090198211 | Convenience IV kits and methods of use - A convenience kit which provides a basic configuration for use in measuring, filling and dispensing medication and flush solutions to IV sets and patient catheters through needleless connectors while improving safety and efficacy by requiring fewer post-sterilization makes and breaks compared to conventional filling and dispensing methods. Further, the kit improves flush compliance by facilitating dispensing of flush solutions and decreases likelihood of infections by providing for flushing of patient lines and catheter connecting fittings without line breaks. Convenience of operation is provided by a two-syringe assembly which is operable by a single hand for selective dispensing accomplished from either of the two syringes while obstructing flow from the other syringe. The kit comprises a clip for stabilizing the two syringe assembly. | 08-06-2009 |
20090198212 | Endoscopic injection needle assembly inluding an endoscopic hood - An endoscopic injection needle assembly and method of using the same. According to one embodiment, the assembly includes an endoscope, an injection needle, an endoscopic hood and a suction source. The endoscope is shaped to include a proximal end, a distal end, and a plurality of longitudinal channels. The distal end of the injection needle is positioned within a working channel of the endoscope. The injection needle is sized relative to the working channel to permit fluid to flow around the injection needle in the working channel. The endoscopic hood is mounted on the distal end of the endoscope and extends distally therefrom, the endoscopic hood being in fluid communication with the working channel and having an opening through which fluid may be drawn into the endoscopic hood. The suction source is applied to the proximal end of the working channel to cause fluid to be drawn into the endoscopic hood through the opening and then proximally through the working channel. In addition, suction causes tissue to be drawn into the endoscopic hood. The injection needle may then be operated to penetrate the suctioned tissued. | 08-06-2009 |
20090198213 | METHOD OF OPHTHALMIC SURGERY AND KIT THEREFOR - A method of micro-incision ophthalmic surgery, comprising, in the order mentioned, the steps of: | 08-06-2009 |
20090198214 | Butterfly Needle Devices and Methods Relating Thereto - In accordance with one embodiment of the present disclosure, a butterfly needle device is described. The device comprises a needle having a proximal end and a distal tip, a base positioned over the needle, a first wing and a second wing each extending from the base and being configured to move between a generally abducted position and a generally adducted position, a spacer element extending from the first wing, a sleeve positioned over the needle, and a bridge element connecting the sleeve to the base. | 08-06-2009 |
20090198215 | ADHESIVE PATCH SYSTEMS AND METHODS - Various embodiments of the present invention are directed to patches for medical devices. In various embodiments, an adhesive patch of a medical device may have selective areas with adhesive material of varying adhesion strengths. In other embodiments, an adhesive patch of a medical device may include adhesive material that may be activated by a catalyst to increase or decrease the adhesion strength of the adhesive material. In further embodiments, a medical device may include a pierceable membrane containing an agent, the pierceable membrane positioned to be pierced by a needle and to cause some of the agent to be carried to the user-patient. | 08-06-2009 |
20090204101 | METHOD OF APPLYING AN INJECTABLE FILLER - Methods for applying injectable fillers are provided. In some embodiments, the methods can result in a reduced risk of an adverse event occurring from the administration of the injectable filler. Also disclosed are devices and kits related to this method. | 08-13-2009 |
20090204102 | INTRADERMAL SYRINGE AND NEEDLE ASSEMBLY - A method for using a needle assembly for an intradermal injection, and a drug delivery device is provided, which includes a needle cannula and a limiter surrounding the needle cannula and includes a skin engaging surface on the limiter. The limiter is moveable from a first position in which an elongate portion of the needle cannula is exposed for access to a medication vial, to a locked second position in which the limiter is not movable from the second position to the first position. In the second position, the needle tip extends beyond the skin engaging surface a distance of about 3 mm or less. | 08-13-2009 |
20090204103 | INJECTION DELIVERY SYSTEM - An injection delivery system for automatically injecting fluid into an injection site includes at least one support element and a carriage moveably mounted to the at least one support element so that the carriage can move linearly relative thereto. The carriage has a support structure for removably receiving and carrying a syringe assembly for movement with the carriage, and a carriage actuator is operable to cause such linear movement of the carriage. A plunger actuator is carried by the carriage so as to move with the carriage, and is adapted to be operably coupled to a syringe plunger for causing linear movement of the syringe plunger within a syringe barrel. The carriage actuator and plunger actuator include respective inputs for receiving movement instructions, and may be coupled to an electronic controller that provides such instructions. | 08-13-2009 |
20090209939 | RECONSTITUTION MEANS FOR SAFETY DEVICE - The present disclosure describes a needle guard device or system that can be used with drugs requiring reconstitution. The needle guard is preferably a passive needle guard that can be used during reconstitution without activating the safety mechanism. Following administration of the medication, the needle guard shields a user from inadvertent needle sticks by extending a protective shield over the needle. | 08-20-2009 |
20090216215 | INSERTION DEVICE FOR INSERTION HEADS AND INFUSION SETS - An insertion device for applying an infusion set to the body of a patient, wherein the device has two actuation members which have to be actuated simultaneously to trigger an insertion movement by which a cannula of the infusion set is introduced into the body and wherein, in some embodiments, one of the actuation members is a securing slide including a contact face to be placed on the body of the patient, the securing slide being actuated by the insertion device being pressed, via the contact face, against the body of the patient. | 08-27-2009 |
20090216216 | METHODS OF PERFORMING A POWER INJECTION PROCEDURE - Methods of performing a power injection procedure are described. One method includes taking an x-ray of a subcutaneously implanted access port in a patient to determine whether the access port includes a radiographic feature indicating that the access port is suitable for flowing fluid at a rate of at least about 1 milliliter per second through the access port, identifying the indicating radiographic feature on the x-ray, and flowing a fluid through the access port at a rate of at least about 1 milliliter per second. | 08-27-2009 |
20090240232 | MULTI-CARTRIDGE FLUID DELIVERY DEVICE - A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments. | 09-24-2009 |
20090247984 | USE OF MICRONEEDLES FOR SMALL MOLECULE METABOLITE REPORTER DELIVERY - Systems that can include a microneedle array and a small molecule metabolic reporter are disclosed. The systems can be used to penetrate the epidermis and monitor the change in concentration of one or more metabolite or analyte. | 10-01-2009 |
20090247985 | EMBOLIC PARTICLE MIXING SYRINGE - A syringe device for agitating and delivering a liquid medication to a patient is provided. The device includes an injecting member, a first syringe, a second syringe and an accumulator. The first syringe is configured to provide the liquid medication to the device. The second syringe is configured to receive the liquid medication from the first syringe. The accumulator is biased to an empty position and cooperates with the second syringe to agitate the liquid medication back and forth between the second syringe and the accumulator. The second syringe is configured to move the liquid medication to the injecting member for patient delivery. | 10-01-2009 |
20090254060 | Motor assembly for injection control device - A spring motor mechanism for use in an injection control device having a metered/controlled injection rate proportional to the rate of withdrawal/injection suitable for cosmetic as well as other applications is described. After the cannula is advanced into an object (person) the cannula is withdrawn to create a tract or tunnel within the targeted area. As the cannula is withdrawn, filler material in the injection control device is uniformly deposited into the tract or tunnel via the automatic metering system. As one feature, the spring motor mechanism automatically retracts the positioning guide that is used in the metering systtem. The spring motor mechanism may be replaceable or customizable, offering the user enhanced safety and convenience of operation for the injection control device. | 10-08-2009 |
20090254061 | METHOD AND APPARATUS FOR REMOVING CEREBROSPINAL FLUID - An apparatus for removing cerebrospinal fluid includes a first needle having a first end, a second end, and a passage extending between the first and second ends. The proximal end of the first needle has a handle and the distal end has a cutting tip adapted to penetrate skin. A second needle is slidably disposed within the passage of the first needle. The second needle has a proximal end, a distal end, and a lumen extending between the proximal and distal ends. The proximal end of the second needle has a handle. The distal end of the second needle has an atraumatic tip and a microfilter in fluid communication with the lumen for removing cerebrospinal fluid. | 10-08-2009 |
20090264857 | LIQUID INFUSION APPARATUS - An apparatus and method are disclosed for controlling infusion of liquid into a patient using a peristaltic pump. The liquid infusion apparatus includes a liquid conduit having a proximal segment, a distal segment and an intermediate segment. The liquid infusion apparatus also includes a flow valve in fluid communication with the intermediate and distal segments. The flow valve includes a shuttle member slidably disposed within a housing about the distal segment, the shuttle member being configured for lateral movement relative to an elongated axis of the distal segment. The shuttle member is configured to operate in a first configuration to impede fluid flow through the liquid conduit and in a second configuration for which fluid flow through the liquid conduit is unimpeded. The shuttle member includes a resilient grasper for selectively engaging and disengaging a mating actuator resiliently received by the grasper. | 10-22-2009 |
20090275914 | Medication Delivery Device - The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having dose setting means and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge, to a use of such device, and to a method of manufacturing or assembling such device. | 11-05-2009 |
20090275915 | Medication Delivery Device - The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having dose setting means and a drive device enabling the administration of a medicinal product from a multi-dose medication cartridge, to a use of such device, and to a method of manufacturing or assembling such device. | 11-05-2009 |
20090275916 | Medication Delivery Device - The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device. | 11-05-2009 |
20090275917 | SKIN TREATMENT SYSTEM AND METHOD - A skin treatment system is provided for applying liquid medication through a controlled intra-dermal injection. The skin treatment system includes a microinjector unit with a proximal end and an opposing distal end. The proximal end of the microinjector unit may be press fitted or twist fit to a distal end of a tube via a luer lock mechanism. A fluid moving chamber is disposed within the microinjector unit. The fluid moving chamber is configured to receive liquid medication and distribute the liquid medication to a plurality of hypodermic needles. The plurality of hypodermic needles are operative for receiving the liquid medication from the fluid moving chamber and delivering the liquid medication to the skin of the patient. The plurality of hypodermic needles extends from the distal end of the microinjector unit. The distal end of the microinjector unit may encompass a variety of different shapes while the needles are maintained equidistantly spaced apart. | 11-05-2009 |
20090281520 | Ocular Implantation Device - An ocular implantation device comprises a housing having a longitudinal axis, a needle configured to receive an implant, and a plunger and a rod operatively coupled together. The plunger and the rod are disposed in the housing and are collectively, translationally moveable along the longitudinal axis of housing. The rod is configured to be receivable within at least a portion of the needle to enable the rod to move an implant therethrough. An actuator is operatively engaged with the plunger such that movement of the actuator in a direction aligned with the longitudinal axis of the housing results in translational movement of the plunger and the rod along the longitudinal axis of the housing in order to deliver the implant through the needle to a target site. An alternative embodiment of the device uses a retractable needle to deliver the implant. | 11-12-2009 |
20090287181 | CATHETER/FILAMENT STYLE DEVICE AND METHODS FOR TREATMENT OF WOUNDS BENEATH THE SURFACE OF THE SKIN - A reduced pressure treatment system includes a filament delivery conduit having a distal end positioned at a subcutaneous tissue site of a patient and a proximal end positioned extracorporeal to the patient. A continuous filament is positioned in the filament delivery conduit such that one end of the continuous filament extends from the proximal end of the filament delivery conduit and another end of the continuous filament extends from the distal end of the filament delivery conduit. The continuous filament forms a filament mass adjacent the tissue site. A reduced pressure delivery conduit is adapted to fluidly communicate with a reduced pressure source and the filaments mass to deliver a reduced pressure to the tissue site through the filament mass. | 11-19-2009 |
20090299328 | Injection device for soft-tissue augmentation fillers, bioactive agents and other biocompatible materials in liquid or gel form - Described herein are injection devices capable of automatically injecting substances into the soft tissue of a patient. The devices can inject low to high viscosity materials at predetermined, user selected injection rates, allowing the operator more control than a traditional syringe. The devices can allow mixing of more than one substance and/or reconstitution of a solid substance for injection. The injection devices described herein can allow the operator to easily inject one or more low to high viscosity liquid or gel soft-tissue augmentation fillers, one or more drugs, one or more other biocompatible materials, or combinations thereof. | 12-03-2009 |
20090306623 | Multiple ratio fluid dispenser - A double syringe delivery system is disclosed for holding a pair of syringes in a manner so as to accommodate the simultaneous activation of the plunger of each syringe in order to effect simultaneous delivery of the contents of each syringe. The delivery system includes a delivery mechanism for delivering the contents of both syringes to a site of application. The delivery system further includes a support member that is positioned between the two syringe bodies. The elongated support member has resilient, C-shaped clamps on one end of the support member. The clamps are designed to be removably clamped onto the applicator so that the syringe barrels will be held together in a parallel manner. The elongated support member further comprises finger grips. A plunger connects the two syringe plungers so that they can also be simultaneously activated. | 12-10-2009 |
20090306624 | DEVICES AND METHODS FOR DELIVERING ACTIVE AGENTS TO THE OSTEOMEATAL COMPLEX - Described here are devices, methods, and kits for treating sinusitis and related respiratory conditions by locally delivering active agents to the osteomeatal complex over a sustained period of time. The devices may be passively fixed within the osteomeatal complex and/or include one or more features that actively fix it within the osteomeatal complex. The devices may optionally include a portion that extends into a sinus ostium, sinus cavity, and/or the nasal passage to deliver an active agent. | 12-10-2009 |
20090312744 | Pulsatile flux drug delivery - A method of delivering a therapeutic fluid to the tissue of a mammal using pulsatile flux to prevent fluid backflow. | 12-17-2009 |
20090318888 | Prefillable Intradermal Delivery Device - An intradermal delivery method for use in intradermally injecting substances into the skin of an animal includes a needle cannula supported by a hub portion that is attachable to a prefillable container. A limiter portion surrounds the needle cannula and extends away from the hub portion toward a forward tip of the needle cannula. The limiter portion includes a skin engaging surface extending in a plane generally perpendicular to an axis of the needle cannula. The skin engaging surface is received against skin of an animal to administer an intradermal injection. The forward tip extends beyond the skin engaging surface a distance that enables penetration of the needle cannula into the dermis layer of the skin of the animal enabling injection of the substance into the dermis layer of the animal. The device includes enclosure means that is moveable for concealing the needle cannula after the injection has been administered. | 12-24-2009 |
20090326511 | METHOD TO PROTECT THE ESOPHAGUS AND OTHER MEDIASTINAL STRUCTURES DURING CARDIAC AND THORACIC INTERVENTIONS - Devices and methods are disclosed for preventing injury to a target tissue in proximity to the heart. The methods may include the use a device to externally manipulate the heart to move a portion of the heart away from the target tissue. The methods may also include applying therapy to the heart with the device. | 12-31-2009 |
20100004625 | FLOATING SPINAL CANNULA AND METHOD OF USE - A spinal cannula for delivering a therapeutic agent to a spinal cord target includes proximal and distal end portions, a middle portion, and a deployable cannula member having distal and proximal end portions and a first lumen extending between the end portions. The spinal cannula includes a fluid delivery line operably connected to the proximal end portion of the deployable cannula member, and a fluid delivery line including a second lumen in fluid communication with the first lumen. The spinal cannula includes a support cannula proximally located from the deployable cannula member and securely connected to a portion of the fluid delivery line. Additionally, the spinal cannula includes a delivery cannula having distal and proximal end portions and a third lumen extending between the end portions for receiving the support cannula. The proximal end portion includes a locking mechanism for releasably engaging the proximal end portion of the support cannula. | 01-07-2010 |
20100004626 | INTRAOSSEOUS DEVICE AND METHODS FOR ACCESSING BONE MARROW IN THE STERNUM AND OTHER TARGET AREAS - Apparatus and methods are provided to access bone marrow at various target areas. Such apparatus may include an intraosseous device operable to penetrate bone at a selected target area and a depth limiter operable to control depth of penetration of the intraosseous device into bone and associated bone marrow. A manual driver and a guide may be included to optimize optimum insertion of the intraosseous device at a selected insertion site on a sternum. | 01-07-2010 |
20100010468 | Retrobulbar Needle and Methods of Use - A syringe and needle assembly includes a needle that extends through the barrel of the syringe and is attached to a proximal portion of the syringe. The distal end of the needle extends through a sleeve attached to the distal end of the syringe. The proximal end of the needle includes a spring which biases the needle proximally, so that the distal tip of the needle is normally retracted within the sleeve. The assembly can be used for injections in portions of a patient's body including delicate tissues that could be damaged if contacted by the needle tip | 01-14-2010 |
20100016829 | APPARATUS AND METHODS FOR RETAINING A NEEDLE ON A MEDICAL INJECTOR - Medical injectors are described herein. In some embodiments, an apparatus includes a medicament container, a needle assembly, a coupler, and a retainer. The medicament container has a distal end and a proximal end and is configured to contain a medicament. The coupler is configured to couple the needle assembly, which includes a needle and a hub, to the distal end of the medicament container. The retainer is configured to be coupled to the needle assembly and the medicament container. The retainer is configured to limit the movement of the needle assembly when the coupler fails to maintain the position of the needle assembly relative to the distal end of the medicament container. | 01-21-2010 |
20100016830 | Injection of Anticoagulant Into Bone Marrow Space - A method for aspirating bone marrow includes the step of injecting anticoagulant into the area Of the bone marrow cavity surrounding the entry site of the aspiration needle. The amount of anticoagulant may be relatively small because the primary objective is to address the damage caused by entry of the needle into and through regions of the bone marrow cavity. As little as 0.5 ml heparin is injected prior to aspiration. Additional anticoagulant is provided in the collection syringe to facilitate further processing, as by centrifugal fractionation of the marrow to obtain desired components. | 01-21-2010 |
20100022988 | INFUSION SET WITH A DATA STORAGE DEVICE - An infusion device, an infusion set and a system and method involving one or the other and/or both, wherein the infusion device interacts with the infusion set, and/or wherein the device, set, system and method ensure that deviations from the therapeutically suitable operating state of an infusion set attached to the infusion device can be detected and rectified in an automated manner or with the assistance of the person using the infusion device. | 01-28-2010 |
20100036362 | Injection System with Hidden Needles - An auto-injector confines all functional components inside an enclosed housing, to keep its needle out-of-sight, at all times. Within the housing, a needle holder positions a needle at a location. A drive mechanism then simultaneously engages the needle with a fluid source and accelerates it with a predetermined momentum for insertion into a patient. After fluid delivery, the withdrawn needle is moved to storage within the housing for subsequent disposal. | 02-11-2010 |
20100042068 | HYDRAULIC INJECTION SYSTEM AND INJECTION METHOD - Disclosed is an injection system ( | 02-18-2010 |
20100057045 | Apparatus, system and method for manipulating a surgical catheter and working device with a single hand - Systems and methods are disclosed that include a guide catheter apparatus insertable through a external body passage of a subject. The guide catheter apparatus includes a substantially rigid shaft and a handle. The shaft has a proximal opening, a distal opening, and a lumen extending between the proximal opening and the distal opening. The handle has a structure to allow a position of the guide catheter to be controlled by some or all of three fingers of one hand of an operator of the handle. The structure of the handle is adapted to permit the operator to position a thumb and index finger of the hand to manipulate a working device inserted into the lumen of the guide catheter, where the working device is manipulable via a portion of the working device immediately adjacent to the handle. | 03-04-2010 |
20100076399 | Fluid dispenser - Dispensing assemblies, methods, and kits of parts for dispensing two separate fluids to an treatment site, including entraining non-atomized flow of a first fluid in an atomized flow of a second fluid, delivering a first fluid upstream from a second fluid, delivering a first fluid and a second fluid with re-shapeable malleable tubes, delivering first and second fluids with releasable connectors maintained by a handle assembly, and kits of parts with angularly offset pockets. | 03-25-2010 |
20100076400 | METHOD AND DEVICE FOR PAINLESS INJECTION OF MEDICATION - A method for providing a substantially painless injection of medication into a patient, including inserting an injection needle having an outside diameter greater than 0.20 mm and less than about 0.38 mm, and injecting a medicament through the needle and into the patient at a substantially constant volumetric flow rate of about 0.05 μL/s to about 50 μL/s that provides a painless injection. The method does not require the use of an anesthetic or that the medical personnel to spend a substantial amount of time performing the injection procedure, is relatively simple and inexpensive to perform and operate, and provides a relatively high degree of safety for both the medical personnel and for the patient. | 03-25-2010 |
20100087796 | Method For Controlling A Pump Drive - A syringe pump and associated computer are provided to achieve an ultra-low flow rate. The computer may generate syntax commands to a motion controller of the syringe pump to displace a plunger by a selected number of steps or increments and pause a period of time before repeating the displace and pause steps. The cycle may be repeated until a desired end condition has been reached. The syringe pump and computer may be embodied as separate linked units or as a standalone unit wherein the computer is an embedded controller located within the syringe pump housing. The invention may also be embodied as a method for achieving ultra-low flow. | 04-08-2010 |
20100094252 | SUBCUTANEOUS DELIVERY TOOL - Exemplary embodiments provide subcutaneous implantation tools and methods of implanting a subcutaneous micro-device using the same. Exemplary embodiments provide subcutaneous implantation tools including a syringe body, a dissection body, and a delivery assembly. Additional exemplary embodiments provide methods of implanting a subcutaneous micro-device, including inserting the dissection body of the tool described by the exemplary embodiments into an implantation site, where the dissection body includes a micro-device, and delivering the micro-device. | 04-15-2010 |
20100094253 | Drive mechanisms suitable for use in drug delivery devices - The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device. | 04-15-2010 |
20100094254 | Formulation Delivery Device - The present invention provides a device for injection of formulations into a patient. In one embodiment the injection is sub-cutaneous. The device is convenient for injecting viscous formulations that would otherwise clog conventional injection devices, for example formulations containing microspheres, suspensions, and other viscous substances. Generally, the device features a needle for piercing the skin, an internal chamber for holding and transmitting fluid, a plunger for applying pressure to the internal chamber, a switch for triggering withdrawal of the needle, a sheath at least partially encompassing the needle and having a flow path within the sheath, and a spring that expands when the switch is triggered, and which thereby at least partially withdraws the needle from the sheath. | 04-15-2010 |
20100094255 | CANNULATED SENSING DEVICE - A cannulated sensing device is disclosed and can include a housing that can have a proximal end and a distal end. A cannula can extend from the proximal end of the housing to the distal end of the housing. Further, a sensor can be attached to the distal end of the housing. | 04-15-2010 |
20100106132 | DRUG CARTRIDGE FOR DELIVERING A DRUG DEPOT COMPRISING SUPERIOR AND INFERIOR COVERS - A drug cartridge is provided for delivering a drug pellet to a site beneath the skin of a patient, the drug cartridge comprising: two or more chambers, each chamber holding a drug pellet and having a proximal end and a distal end, the proximal end of the chamber having an opening to receive the drug pellet and a plunger, the distal end of the chamber having an opening for receiving the plunger and passage of the drug pellet, superior and inferior locking covers disposed on at least one chamber opening, wherein movement of the plunger to an extended position moves the drug pellet within the chamber of the cartridge out the distal end of the chamber and out of the drug cartridge. Devices that utilize the drug cartridge are also provided. | 04-29-2010 |
20100106133 | DRUG CARTRIDGE FOR DELIVERING A DRUG DEPOT COMPRISING A BULKING AGENT AND/OR COVER - A drug cartridge is provided for delivering a drug pellet to a site beneath the skin of a patient, the drug cartridge comprising: two or more chambers, each chamber holding a drug pellet and having a proximal end and a distal end, the proximal end of the chamber having an opening to receive the drug pellet and a plunger, the distal end of the chamber having an opening for receiving the plunger and passage of the drug pellet, a bulking agent disposed within at least a portion of each chamber, wherein movement of the plunger to an extended position moves the drug pellet within the chamber of the cartridge out the distal end of the chamber and out of the drug cartridge. In some embodiments, instead or with the bulking agent pierceable superior and inferior covers are used to contain the drug pellets. | 04-29-2010 |
20100106134 | Inner Ear Drug Delivery Device and Method - A drug delivery device for the inner ear is described. A drug delivery member for the inner ear without any stimulation electrodes has an intra-cochlear portion that penetrates into the inner ear of the patient and contains a drug eluting polymer material having at least one therapeutic drug which is released over time in a therapeutically effective amount into fluid in the inner ear of the patient. | 04-29-2010 |
20100121307 | Microneedles, Microneedle Arrays, Methods for Making, and Transdermal and/or Intradermal Applications - Embodiments are directed to microneedle array devices for intradermal and/or transdermal interaction with the body of patient to provide therapeutic, diagnostic or preventative treatment wherein portions of the devices may be formed by multi-layer, multi-material electrochemical fabrication methods and wherein individual microneedles may include valve elements or other elements for controlling interaction (e.g. fluid flow). In some embodiments needles are retractable and extendable from a surface of the device. In some embodiments, interaction occurs automatically with movement across the skin of the patient while in other embodiments interaction is controlled by an operator (e.g. doctor, nurse, technician, or patient). | 05-13-2010 |
20100130958 | Device and Methods for Subcutaneous Delivery of High Viscosity Fluids - The present invention provides infusion devices and methods for subcutaneous delivery of high viscosity fluids. The devices and methods described are innovative subcutaneous infusion systems that allow for the rapid delivery of viscous therapeutic fluids while avoiding adverse side effects and promoting patient comfort. The devices and methods described are also useful for rapid delivery of high volumes of therapeutic fluids. | 05-27-2010 |
20100137829 | Injection Gateway - The current invention relates to an injection gateway ( | 06-03-2010 |
20100137830 | MEDICATION DELIVERY DEVICE COMPRISING A PLURALITY OF RESERVOIRS - The present invention relates to a medication delivery device for delivering a set dose of medicament, the medication delivery device comprising pump means having first and second pump chambers. The first pump chamber is adapted to transfer medicament from a first collapsible reservoir to an outlet arrangement, said outlet arrangement being in fluidic communication with an associated hypodermic needle. The second pump chamber is adapted to transfer substance from a second reservoir to the outlet arrangement, wherein the first pump chamber is adapted to deliver the set dose of medicament during one or more pump strokes, the stroke volume(s) of said one or more pump strokes being variable. | 06-03-2010 |
20100137831 | METHODS AND DEVICES FOR INTRADERMAL INJECTION - Devices and methods for intradermal (ID) administration of diagnostic and therapeutic agents, vaccines and other compounds into the dermal layer of the skin are disclosed. The devices and the methods simplify the ID injection process and increase the consistency of the placement of the needle tip in the dermal space close to the skin surface allowing for a shallow cannula placement in the dermis. Furthermore, the devices and methods broaden the number of sites suitable for ID injection and make the ID injection possible with limited training. | 06-03-2010 |
20100137832 | Auto-Injector Apparatus - An auto-injector apparatus includes a flexible container containing a liquid medicant, a needle communicated with a container, a housing with a container being received in the housing, a pump disposed in the housing and positioned to engage the flexible container and expel the medicant from the container through the needle upon relative movement between the pump and the container, and a main drive spring operably associated with the needle to extend the needle from a first needle position wherein the needle is completely received in the housing to a second needle position wherein the needle protrudes from the housing. The pump may be a roller. | 06-03-2010 |
20100137833 | Methodology for drug delivery device with sliding valve - Drug delivery devices adapted to receive liquid medication vials to fill a reservoir, utilize sliding through valves that are closed except when driven by force of liquid medication pushed by a plunger to an open position to feed the medication via needle to a patient or via a connection to an IV port. The devices have multiple seals and automatically close up when pressure on the plunger is released. The methodology is also included. | 06-03-2010 |
20100145303 | DEVICE FOR DRUG DELIVERY - Delivery of more than one therapeutic fluid as a means to control symptoms of a health conditions is disclosed. More than one therapeutic fluid may be dispensed from more than one reservoir and delivered to a user's body via one or more cannula that penetrate the skin. The therapeutic fluids may be delivered by action of one or more pumping mechanisms that may be controlled by a processor in a portable, ambulatory device. The therapeutic fluids may optionally be insulin and one or more of an amylin analog, pramlintide acetate and an exenatide, and the health condition may optionally be diabetes. | 06-10-2010 |
20100145304 | THERMOCHEMICAL ABLATION OF BODILY TISSUE - Thermochemical ablation techniques may provide ablation of bodily tissue using chemical reaction energy. | 06-10-2010 |
20100145305 | LOW VOLUME ACCURATE INJECTOR - Substance-administration apparatus is provided, including a housing and a needle couplable to the housing, having a skin-insertion portion 0.3-2.5 mm in length and an outer diameter that is less than 0.23 mm. The apparatus also comprises a dosage regulator coupled to the housing, which regulates a dosage of the substance injected in a single injection through the needle. The dosage is selectable in accordance with a setting of the dosage regulator to be one of a plurality of selectable dosages. The plurality of selectable dosages includes at least one dosage that is less than or equal to 10 ul. The apparatus further includes an injection driver, activatable by a user to drive the substance through the needle. Other embodiments are also described. | 06-10-2010 |
20100152700 | INTEGRATED STORAGE AND DELIVERY SYSTEMS FOR NUTRITIONAL COMPOSITIONS - Apparatuses, kits and methods useful in the storage and delivery of nutritional compositions and other fluids are described. In a general embodiment, an integrated storage and delivery system for nutritional compositions comprises a container defining a chamber, a finish, and a penetrable seal. The finish defines an opening and the penetrable seal separating the chamber from an external environment. A spike assembly is attached to the container. The spike assembly including a cap and a spike. The cap is engaged with the finish of the container and the spike defines a projection having a distal end defining a second opening. The projection is moveable between a first position in which the distal end is adjacent a first side of the penetrable seal and a second position in which the distal end is adjacent a second side of the penetrable seal. | 06-17-2010 |
20100152701 | METHODS AND DEVICES FOR DELIVERING AGENTS ACROSS BIOLOGICAL BARRIERS - The invention provides for microneedle devices for delivering agents across biological barriers. The microneedles include agent reservoirs integrated into the bodies of the microneedles, themselves. | 06-17-2010 |
20100160894 | Automatic injection device - The invention provides an automatic injection device for providing a subcutaneous injection of a substance into a user, comprising: a housing having an open first end and a second end; a syringe movably disposed in the housing, the syringe including a barrel portion for holding the substance, a hollow needle in fluid communication with the barrel portion for ejecting the substance from the syringe, and a bung for sealing the barrel portion and selectively applying pressure to the substance to force the substance through the hollow needle; a plunger for first moving the syringe towards the first end such that the needle projects from the first end and subsequently applying pressure to the bung, the plunger including a rod connected at a first end to the bung, a compressible expanded central portion and a flange between a second end of the rod and the compressible expanded central portion; and a biasing mechanism for biasing the plunger towards the first open end of the housing, the biasing mechanism disposed about the second end of the rod between the flange and the second end of the housing. The present invention also provides methods and kits for using an automatic injection device, and methods and kits for promoting an automatic injection device comprising a medication based on advantageous properties of the device as compared to a pre-filled syringe. The invention also provides methods and kits for training a recipient on use of the automatic injection device. | 06-24-2010 |
20100160895 | Apparatus and Method for Transdermal Delivery of Parathyroid Hormone Agents - An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the PTH-based agent is contained in a biocompatible coating that is applied to the microprojection member. | 06-24-2010 |
20100174267 | HOLLOW CURVED SUPERELASTIC MEDICAL NEEDLE AND METHOD - A needle assembly | 07-08-2010 |
20100174268 | METHODS OF VENTING, SEALING, AND DISPENSING FROM A MEDICAMENT CONTAINER - A sealing assembly movable within an opening of a medicament container allows (1) gases to be vented from the container, (2) medication to be stored in the container, and (3) medication to be dispensed from the container. Methods of limiting exposure of the medication to oxygen to prevent degradation of the medication while in the medicament container are also disclosed. | 07-08-2010 |
20100179508 | PACKING FOR AN INFUSION SET AND METHOD OF APPLYING AN INFUSION SET - The present invention relates to a packing for an infusion set. An infusion set for intermittent or continuous administration of a therapeutical substance, such as insulin, comprises an infusion part having a cannula penetrating the skin of a patient and a connector which connects the infusion part with a medical device such as an adaptor for a syringe or an insulin pump. The insertion of the infusion part will be performed with an insertion needle which is delivered together with the infusion part under sterile conditions. The packaging comprises an impenetrable part ( | 07-15-2010 |
20100179509 | INTRATHECAL CATHETER HAVING A STYLET WITH A CURVED TIP AND METHOD OF USE - An apparatus includes a catheter for an intrathecal drug delivery system and a stylet having a curved forward end. Preferably, the curved forward end has a shape in the form of a “J” or a “C.” Also preferably, the catheter has a distal end that conforms to the curved forward end of the stylet. Thus, the present invention provides a catheter having a blunt forward end that minimizes the risk of penetrating the substance of the spinal cord. Additionally, the curved forward end of the stylet can be formed of a springy material so that it straightens out during the processes of insertion through a guide needle and retraction from the needle. | 07-15-2010 |
20100185177 | HANDS-FREE INTRAMUSCULAR INJECTION DEVICE - An injection device for hands-free, transdermal injection of a liquid medicament, configured for easy handling and for manipulation by the use of the hand or fingers of the medical technician The device includes a housing having a base for attachment of the housing to the skin of a patient, an injection needle, and a reservoir for containing a vaccine. The device also has a means for expressing the vaccine from the reservoir through the injection needle that includes a mechanical force means for storing potential energy and exerting a mechanical force, and a hydraulic force means for transmitting the mechanical force into a hydraulic force. The hydraulic force is exerted onto the vaccine in the reservoir, thereby pressurizing and passing the vaccine through the injection needle. The mechanical force means is typically a mechanical spring, and the hydraulic force means is typically a closed hydraulic circuit. | 07-22-2010 |
20100185178 | INJECTION DEVICE - An injection device including a syringe having a needle, a barrel and a plunger. The device is configured to provide an automatic injection cycle and includes a drive coupling arrangement between a driving spring and the syringe. In operation, a drive force can be selectively transmitted between the respective first and second parts of the drive coupling arrangement depending upon their relative rotational positions such that, when the first and second parts are in a first relative rotational position during the dispensing stage, a driving force is transmitted to the plunger to drive the plunger into the barrel, and, when the first and second parts are in a second relative rotational position during the retraction stage, no force is transmitted to the plunger to allow the plunger and the syringe to retract. | 07-22-2010 |
20100191217 | INJECTION DEVICE WITH A SPRING FOR A NEEDLE PROTECTING SLEEVE - An injection device including a housing, a needle guard sleeve displaceable relative to the housing, and a spring coupled to the guard sleeve such that the guard sleeve can be moved by the spring distally from a proximal position to an end position, the spring also being coupled to a forward drive element displaceable relative to the housing in a drive direction wherein the spring is tensioned upon a movement of the forward drive element in the forward drive direction. | 07-29-2010 |
20100191218 | INFUSION DEVICE AND METHOD FOR INFUSING MATERIAL INTO THE BRAIN OF A PATIENT - A fluid infusion device and a method of using the same. The device includes an outer, flexible guide catheter having a distal end for introduction beneath the skull of a patient and a proximal end remaining external of the patient. A flexible infusion fiber is located within the guide catheter and has a distal end extending outwardly from the guide catheter to be located in a target area within the patient's brain. The infusion fiber can be fixed or axially movable within the guide catheter. In the latter embodiment, the proximal end of the infusion fiber extending outwardly from the guide catheter can be manipulated to locate the distal end of the infusion fiber in the target area. An infusion pump is connected to the proximal end of the infusion fiber to infuse a minute quantity of fluid at an extremely low flow rate into the brain of the patient. | 07-29-2010 |
20100198189 | SPINAL MULTISEGMENTAL CELL AND DRUG DELIVERY SYSTEM - Delivery devices and methods related thereto may be used in humans for spinal delivery of cells, drugs or vectors. The patient population may include patients with spinal traumatic injury, amyotrophic lateral sclerosis, multiple sclerosis, spinal ischemia and any other spinal neurodegenerative disorders which will require spinal cell, vector or drug delivery. Unlike conventional methods which require multiple injection sites to make multiple, localized substrate deliveries, the delivery devices and methods of the present invention may allow for multiple substrate delivery locations with homogeneous substrate delivery with a single injection site. | 08-05-2010 |
20100211042 | Drug Delivery Device - Embodiments of the invention generally provide a device and method for minimizing injection pain and preventing needle clogging during injection of a drug formulation into skin. Generally, the invention provides a device comprising a needle having a point to penetrate skin on one end, a hub having a diameter larger than that of the needle attached to the opposite end of the needle and connectable to a housing defining a chamber for receiving a formulation, and a polymer wrap attached to the hub, wherein the polymer wrap is tapered to the needle so as to pass through skin when the point is inserted into the skin, and wherein a space between the needle and the polymer wrap lies in a flow path of the formulation into the skin, such that formulation is injected through the space between the needle and the polymer wrap. | 08-19-2010 |
20100211043 | METHODS FOR FIXING A GASTROINTESTINAL DEVICE IN THE GI TRACT - A method for fixing a gastrointestinal (GI) device in a GI tract, the method including introducing a substance into a tissue of the GI tract that reduces or eliminates the tissue's physiological capability to reject foreign bodies, and fixing a GI device into the tissue where the substance has been introduced. | 08-19-2010 |
20100217230 | Systems, Devices and Methods for Fluid/Drug Delivery - Fluid delivery systems, methods and devices for delivering a therapeutic fluid to the body of the patient are disclosed. A fluid delivery device for delivering fluid to the body of the patient includes a housing having an upper wall and a lower wall, wherein the upper wall includes an upper opening and the lower wall includes a lower opening, a well-arrangement mechanism configured to be disposed inside the housing and between the upper wall and the lower wall and including a tubular member having a bore, wherein the bore is configured to be disposed between the upper opening and the lower opening, and a penetrating cartridge for delivery of therapeutic fluid to the body of the patient, wherein the penetrating cartridge is configured to engage the bore following its insertion through the upper opening and the lower opening, wherein therapeutic fluid is configured to be delivered through the tubular member into the penetrating cartridge into the body of the patient when the penetrating cartridge engages the bore. | 08-26-2010 |
20100217231 | Device for administering an at least two-component substance - The device for administering an at least two-component substance comprises a concentric lumen arrangement including (i) an inner cannula having a lumen with an inlet opening at a first end and a tip with an outlet opening at a second end opposite its first end, and (ii) an outer sheath having opposite first and second ends facing the respective first and second ends of the inner cannula, and surrounding the inner cannula along an axial length between the first and second ends of the inner cannula, wherein the outer sheath at its second end is sealingly and fixedly connected to the inner cannula and defining an outer lumen around the inner cannula, and wherein the inner cannula is provided with at least one opening for providing fluid communication between the outer lumen around the inner cannula and the lumen of the inner cannula. | 08-26-2010 |
20100222767 | Markers for needles including temporary and pen injector types - A Marker on the dorsal (top) side of a needle allows a visually challenged user to maintain an orientation of the needle from a point within the user's comfortable visual focusing range to a desired injection site | 09-02-2010 |
20100222768 | METHODS FOR CAPACITANCE VOLUME CORRECTION IN FLUID DELIVERY SYSTEMS - A method of capacitance volume correction in fluid-containing expandable bodies and associated fluid pathways is disclosed for application in fluid delivery systems used to supply fluids to patients during radiographic imaging procedures including angiography. One embodiment is directed to a method of controlling delivery of fluid to a downstream process, including providing a fluid-containing expandable body, including a pressurizing element and in fluid communication with the downstream process, pressurizing the expandable body by moving the pressurizing element forward in the expandable body to reduce volume therein, and ceasing movement of the pressurizing element after allowing the pressurizing element to over-travel a sufficient distance to compensate for expansion of the expandable body under pressure. The expandable body may be a syringe and the pressurizing element may be a plunger disposed within the syringe. Movement of the pressurizing element is controlled by an algorithm associated with a computer. | 09-02-2010 |
20100228225 | METHOD AND SYSTEM FOR DELIVERY OF NEUROTOXINS - A method and system for delivering a neurotoxin into the body of a subject is disclosed. The method includes sequentially applying one or more arrays of micro needles on a portion of the skin of the subject that requires treatment. The micro needles are pre-coated with the neurotoxin on an array comprised of 10 to 1,000 micro needles over an area of 1 mm | 09-09-2010 |
20100228226 | Inserter Having Two Springs - The invention relates to an inserter for a medical device e.g. an infusion set or the like for intermittent or continuous administration of a therapeutical substance, such as e.g. insulin. The inserter comprises a needle hub comprising an insertion needle and two elastic elements assuring automatic insertion and automatic retraction of the insertion needle. Activation of the first elastic element ( | 09-09-2010 |
20100228227 | DUAL ACCESS SINUS SURGERY METHODS AND SYSTEMS - A method for sinus surgery includes piercing first and second access openings into the anatomy of a human subject to access an inaccessible sinus site for cooperatively manipulating respective first and second surgical instruments inserted through the openings. One instrument, for example an endoscope, can permit viewing of the sinus site while the other instrument is manipulated to effect a treatment at the sinus site. The maxillary and other sinuses can be accessed and anti-inflammatory and other treatments can be applied. Systems and instruments for performing such sinus surgery methods are also disclosed. | 09-09-2010 |
20100234828 | Methods and Compositions for Facilitating Arterial Access - Provided are methods and compositions for locally increasing arterial diameter and providing local anesthesia in a subject. The methods include applying to a skin site of the subject a topical composition that includes a vasodilation agent and an anesthetic agent in a manner sufficient for locally increasing arterial diameter and providing local anesthesia in the subject. In some embodiments, the method includes inserting a cannula into an artery at the skin site of the subject. Also provided are topical compositions that find use in performing the subject methods. | 09-16-2010 |
20100241102 | INTRAVITREAL INJECTION DEVICES AND METHODS OF INJECTING A SUBSTANCE INTO THE VITREOUS CHAMBER OF THE EYE - Intravitreal injection devices include an injection assembly adapted to receive an injector, and an alignment guide adapted to facilitate placement of the injector relative to a patient's eye for injecting an injectant therein. The injection assembly, in response to a user input, is adapted to automatically and sequentially first, translate the injector into the patient's eye, and then second, dispense the injectant from the injector. In some embodiments the injector is a typical syringe. Some embodiments are adapted to receive syringes having different configurations. Methods of injecting an injectant into a patient's eye are also provided. | 09-23-2010 |
20100241103 | CARTRIDGE ADAPTER FOR USE IN AN INFUSION SYSTEM - Infusion systems for pumping fluid into a body of a user, and methods for providing infusion systems, are disclosed. The infusion systems include an infusion pump, wherein the infusion pump comprises an infusion pump housing including a cavity. A fluid storage is removably inserted into the cavity of the infusion pump housing wherein, the fluid storage comprises a cartridge and an adapter connected to the cartridge such that the adapter encases the cartridge, and an infusion set is removably connected to the fluid storage. | 09-23-2010 |
20100249747 | Transdermal venous access locking solution - Compositions and methods of employing compositions in flushing and coating medical devices are disclosed. The compositions include combinations of a chelating agent, anticoagulant, or antithrombotic agent, with a C | 09-30-2010 |
20100249748 | NEEDLE SHIELD FOR INJECTIONS - A needle shield for hiding a needle from a patient during an injection is disclosed. The needle shield comprises an attaching portion for attaching the needle shield to a syringe and an opaque collapsible element extending from the attaching portion, the collapsible element having an orifice extending therethrough and being of a sufficient length to conceal a needle from view when the needle is disposed in the orifice, and wherein the collapsible element collapses and conceals the needle as the needle is inserted into a patient's skin and expands to retain its original shape as the needle is withdrawn from the patient's skin so that the patient does not see the needle during an injection. | 09-30-2010 |
20100262118 | Methods for Identifying Areas of a Subject's Skin that Appear to Lack Volume - The present embodiments relate to methods and systems for identifying areas of a subject's skin that lack sufficient volume. In some embodiments, this can be used to direct the administration of filler compositions or the application of techniques that increase the volume or firmness of the area. In some embodiments, the methods and systems provide for improved aesthetic benefit as well as suitability for instruction and training. In some embodiments, the methods are especially useful in the administration of dermal fillers to a subject. | 10-14-2010 |
20100262119 | RETRACTABLE NEEDLE ASSEMBLY AND SYRINGE UTILIZING THE SAME - An injection device including a barrel, a hollow plunger having a portion structured and arranged to move within the barrel, a needle unit, and a safety system that one of automatically causes the needle unit to retract into the plunger when the plunger reaches a substantially fully depressed position and utilizes a frangible or breakable seal arranged within the plunger. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way. | 10-14-2010 |
20100262120 | METHOD AND DEVICE FOR CONTROLLING DRUG PHARMACOKINETICS - Methods and devices for administration of substances into at least two compartments of skin for systemic absorption and improved pharmacokinetics, based on biphasic or bimodel kinetic profiling. | 10-14-2010 |
20100262121 | Pre-Filled Cartridge Plunger Method - A method involving a syringe, a pre-filled cartridge, a needle, a guard, and a release mechanism is described. The method may involve inserting the cartridge into the syringe. In some versions, the method may involve releasing the guard to cover a portion of the needle. In some versions, the method may involve the release retaining the guard in a retracted position. In some versions, the release may be operable to be actuated to release the guard. In some versions, the guard may be extended and locked once extended to cover the needle. | 10-14-2010 |
20100262122 | Pre-Filled Syringe Having Internal Guard - A method involving a syringe, a plunger, a needle, and a guard is described. The method may comprise the guard moving and/or translating within the syringe. In some versions, the plunger may be inserted into a syringe body of the syringe. The plunger may be moved within the syringe body. In some versions, the guard may have a retracted position, and the guard may travel axially within the syringe body. In some versions, the guard may translate within the syringe body such that it touches the skin of the patient. In some versions, the guard may cover the needle by axial translation within the syringe body. | 10-14-2010 |
20100262123 | Pre-Filled Syringe Having Flexible Hinge - A method of using a syringe and a flexible member is described. In some versions, the method may involve providing a syringe, a needle, a pre-filled cartridge, an adapter, a flexible member, a biasing element, and a guard. The method may involve retaining the guard, releasing the guard by actuating the flexible member to translate the guard in the distal direction to cover the needle, and locking the guard. In some versions, the flexible member may have a first and second position for actuation. In some versions, the flexible member may engage and disengage the guard to retain and release the guard. | 10-14-2010 |
20100268189 | SYRINGE SYSTEM FOR CONTROLLED DELIVERY OR REMOVAL OF MATERIAL - Embodiments disclosed herein relate to syringe systems for delivering and removing materials, instrument kits that include the syringe systems provided herein, and methods of using the syringe systems and kits provided herein. | 10-21-2010 |
20100268190 | Medical device to be used by a patient - A medical device to be used by a patient, having release means for administering a drug, in particular subcutaneously, and lockable triggering means for triggering the administration of the drug, characterized by telecommunication means, which are connected to the lockable triggering means in order to activate the triggering means in response to the reception data from a remote unit. The device according to the invention in particular assists in the self-injection of therapeutic agents by a patient and reduces the risk of an improper application. | 10-21-2010 |
20100274222 | METHODS AND DEVICES FOR PARANASAL SINUS DRUG DELIVERY - Described herein are methods and devices for delivering a drug to the frontal sinus system. An inflatable implant is positioned within the frontal sinus system using an anchoring means secured within the frontal sinus cavity. A drug-containing fluid is released directly into the frontal sinus drainage system. | 10-28-2010 |
20100280486 | SYSTEM AND METHOD FOR DELIVERING AND MONITORING MEDICATION - A method of delivering medication to a patient utilizing a medication delivery system is provided. A first medication to be delivered to the patient is supplied. The patient's identity is verified. The first medication is selected on a user interface to be delivered to the patient. The volume of the medication the patient will receive is entered. The first medication is injected into the patient through a flow sensor assembly. The flow rate and the volume of the first medication delivered to the patient are monitored by the flow sensor assembly while the injection occurs. A visual display provides information related to the injection. The method updates the patient's electronic medical administration record to capture the information regarding the injection of the first medication. | 11-04-2010 |
20100280487 | METHOD OF REMOVING A STYLETTE FROM A CATHETER - A hydrophilic coated stylette is pre-loaded in an implantable catheter. The hydrophilic coated stylette is wetted with saline to activate the hydrophilic coating. The stylette loaded catheter is tunneled, typically through muscle and tissue, to a desired target site within the body. The hydrophilic coated stylette is then removed from the catheter while maintaining the catheter intact. The proximal end of the catheter can be connected to an outlet of an implantable infusion pump so that medicament can be delivered directly to the target site. | 11-04-2010 |
20100280488 | APPARATUS AND METHODS FOR DELIVERING FLUID AND MATERIAL TO A SUBJECT - The present invention provides fluid and material delivery methods and devices for practicing the methods. The invention provides a method of delivering cellular material comprising injecting the cellular material into a subject such that the injected cells retain their inherent morphologic characteristics upon injection. The method comprises the steps of aspirating the cellular material into a fluid delivery device which incorporates a syringe arrangement. The cellular material is aspirated into the main body of the syringe until the desired amount of a material has filled the syringe body. The needle of the fluid delivery device is then inserted into the skin of a subject at an angle about parallel to the skin until a desired depth has been reached. The cellular material is then injected in the subject until the desired volume of material has been injected. The needle of the device is then rotated approximately 45 to 90 degrees and the needle is removed from the injection site. | 11-04-2010 |
20100286654 | Multiple Thermal Sensors in a Multiple Processor Environment for Temperature Control in a Drug Delivery Device - In various embodiments, an ophthalmic injection device may include a dispensing chamber, a first thermal sensor coupled to the dispensing chamber, a temperature control layer coupled to the dispensing chamber, a second thermal sensor coupled to the dispensing chamber, and a first processing device. The first processing device may be configured to receive temperature information from the first thermal sensor and the second thermal sensor and control the temperature control layer using the received temperature information. In some embodiments, the first processing device may receive temperature information directly from the second thermal sensor (e.g., in analog form) and may compare the temperature information from the first thermal sensor (e.g., received from the second processing device in digital form) and the second thermal sensor to detect temperature offsets between the two sensors. | 11-11-2010 |
20100286655 | Targeted Drug Delivery Device and Method - A targeted drug delivery device is provided. The device comprises an elongated member with proximal and distal ends, a plurality of infusion ports associated with the distal end of the elongated member, and a selector mechanism for selectively placing an introducer port into fluid communication with at least one infusion port. A method for treating tissue is also provided. The method comprises introducing a medical device into the tissue, selecting a region of the tissue to treat, positioning the medical device in proximity to the region, and introducing a medicament through the device to treat only that region. | 11-11-2010 |
20100298807 | APPLICATOR FOR INSERTING AN IMPLANT - The invention pertains to an applicator ( | 11-25-2010 |
20100298808 | METHOD AND A DELIVERY DEVICE FOR ADMINISTERING AN ACTIVE SUBSTANCE TO A SUBJECT - A delivery device ( | 11-25-2010 |
20100298809 | Method of Using Prefilled, Single Dose, One Time Use Self-Destructing, Auto-Disabling Safety Syringe - The present invention relates to the method of use for a single dose, single use, self-destructing, auto-disabling safety syringe. The invention successfully addresses and solves the problems of the prior art by combining the use of COC injection molding with the advantages presented by the ampoule cartridge and the traditional safety syringe all integrated into a single device. A pre-filled ampoule or barrel is molded with minimal draft enabling the syringe's piston plunger to be partially self-lubricated by the syringe's contents. The addition of an internal auto disabling coupler to the piston plunger allows the device to be used only a single time. In addition, the present invention's structure is such that its safety sleeve necessarily moves forward to cover the syringe's needle after use. The invention's elements solve the biocompatibility and safety problems of the prior art and provide an exact dose, prefilled, single use, safety syringe. | 11-25-2010 |
20100318060 | Injection Device With Rotatable Dose Setting - An injection device comprising a housing and a dose setting mechanism including a dose setting element. Contrary to prior art injection devices, the dose setting element can only be set at a few different dose settings. This is established by forming the dose setting element as a rotatable dish concealed within the housing and having a number of projections projecting outside the boundaries of the housing through a slot in the housing. A dose is set by activating a projection which in addition provides the user with a tactile guidance. Usually one projection is provided for one dose setting limiting the number of doses to be set to the number of projections. | 12-16-2010 |
20100324528 | DOSE SETTING MECHANISM FOR PRIMING A DRUG DELIVERY DEVICE - A method and system for priming a drug delivery device. The drug delivery device includes a dose dial sleeve and an internal housing portion. The dose dial sleeve is coupled to the internal housing. The dose dial sleeve rotates on a substantially circumferential rotational path during priming of the drug delivery device. Further, the dose dial sleeve rotates on a helical path during dose setting of the drug delivery device. | 12-23-2010 |
20100324529 | IMPLANT PELLETS AND METHOD USING SAME - A system comprising a plurality of implantable pellets, wherein one such implantable pellet delivers localized, controlled and sustained release of a predetermined quantity of one or more pain relief agents, in optional combination with one or more anti-inflammatory agents, one or more polymeric excipients, and/or one or more surfactants. An anesthetic/analgesic pellet is used in combination with one or more pharmaceutical pellets as part of a single procedure to provide desired a pharmaceutical to the animal while simultaneously alleviating pain and, optionally, inflammation at the injection site. | 12-23-2010 |
20100324530 | HOLLOW NEEDLE - The present invention is a hollow needle for attachment to a syringe, through which a liquid can be delivered to the stratum granulosum and/or beneath the epidermis, preferably to an area consisting from the stratum granulosum (included) to reticular dermis (included) and more preferably beneath the papillary dermis during a cosmetic procedure, the needle comprising a distal tip and including a lateral aperture adjacent to the distal tip, wherein the liquid exits the needle via the lateral aperture, and wherein the needle is flexible. Apparatus comprising a needle of the invention and a syringe, and a method of use thereof, is also provided. | 12-23-2010 |
20100324531 | APPARATUS AND METHODS FOR INJECTING HIGH VISCOSITY DERMAL FILLERS - A method includes inserting a distal end portion of a needle of a medical injector into a skin of a body. An energy source operatively coupled to the medical injector is actuated such that a dermal filler is conveyed from the medical injector into the skin through the distal end portion of the needle. The distal end portion of the needle is moved within the skin during the actuating. | 12-23-2010 |
20100331814 | Systems And Methods For Atraumatic Implantation Of Bio-Active Agents - Methods and apparatus are provided for delivering a bioactive agent in a needle track formed in a target tissue mass, following formation of the needle track, by avoiding impingement of the agent against target tissue at high velocity or by using capillary action to draw the bioactive agent out of the needle during needle withdrawal. The apparatus comprises a catheter and a needle disposed within the catheter and configured to be selectively extended into the tissue mass to a predetermined depth, while dispensing the agent simultaneously with retraction of the needle along the needle track. Alternatively, or in addition, the needle may be configured to create a tissue space surrounding a distal or lateral surface of the needle, into which the bioactive agent to be infused. | 12-30-2010 |
20110004191 | DOSING MECHANISM FOR A DRUG DELIVER DEVICE - A maximum settable dose feature is disclosed that is set by a user or health care professional one time that prevents future injections from exceeding the desired maximum dose. The feature includes a locking band initially in an unlocked configuration, which transforms to a locked configuration when activated after setting a desired maximum dose. The feature can include a trigger mechanism to transform the locking band to the locked configuration. | 01-06-2011 |
20110009847 | SYSTEMS AND METHODS FOR CREATING AND USING SUCTION BLISTERS OR OTHER POOLED REGIONS OF FLUID WITHIN THE SKIN - The present invention generally relates to devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications, for example, devices for delivering and/or withdrawing fluid from subjects, e.g., through the skin. In some embodiments, the device includes a system for accessing an extractable medium from and/or through the skin of the subject at an access site, and a pressure regulator supported by a support structure, able to create a pressure differential across the skin at least a portion of the access site. The device may also include, in some cases, a sensor supported by the support structure for determining at least one condition of the extractable medium from the subject, and optionally a signal generator supported by the support structure for generating a signal relating to the condition of the medium determined by the sensor. | 01-13-2011 |
20110034902 | INJECTION DEVICE FOR DELIVERING A FIXED DOSE OF LIQUID DRUG - An injection device ( | 02-10-2011 |
20110040279 | Particle Delivery - A method for delivering particles to a target location of a subject includes slidably disposing a polymeric carrier in a lumen of a catheter. The lumen extends in the catheter from a proximal opening to a delivery region. The method further includes inserting the delivery region of the catheter in the target location of the subject and forcing the particles through the lumen of the catheter to cause the carrier and the particles to exit the delivery region of the catheter. The particles may be cells or drug-loaded microspheres. The carrier can serve to retain the particles in the target location for a period of time. For treatment of vertebral disc degeneration, the particles can be stem cells, the carrier can be formed from collagen, and the target location can be the nucleus pulposus. | 02-17-2011 |
20110040280 | INJECTOR - An injector includes a support tube having one end surface to be brought into contact with skin, a movable tube advanceable in the support tube in the direction of the skin, an injection needle communicating with the movable tube, a plunger advanceable in the movable tube in the direction of the skin to introduce medicinal liquid filled in the movable tube to the injection needle, and a sealing material provided at the tip of the support tube and penetratable by the injection needle to penetrate the sealing material. In an initial state, the tip of the injection needle is sealed by the sealing material. | 02-17-2011 |
20110046601 | PUNCTURABLE MEMBRANE FOR SAFETY SYRINGE - A safety syringe may define a variable fluid chamber and detached needle assembly. The variable fluid chamber may be hermetically sealed off from the environment or ambient air until the needle assembly is attached to a syringe body of the safety syringe. A proximal end of the variable fluid chamber is sealed off from the environment via a seal between a piston and syringe body. The distal end of the variable fluid chamber may be sealed off from the environment via a barrier covering the distal end of the syringe body. The barrier may be punctured to allow fluid to through therethrough at or about the same time when the needle assembly is attached to the distal end portion of the syringe body. | 02-24-2011 |
20110046602 | DEVICES AND METHODS FOR FLUID ADMINISTRATION - Improved fluid delivery devices and systems are disclosed, including drug delivery devices and systems, and methods that permit, inter alia, the rapid sequential delivery of two or more fluids to a single external fluid flow or intravenous line. | 02-24-2011 |
20110046603 | Syringe Assembly with Pivoting Plunger and Integral Tip Guard - The invention provides a syringe assembly comprising a syringe barrel having an inside surface defining a chamber, an open proximal end, and a distal end having an opening therethrough. An elongated plunger rod extends between a first end and a second end, with a cap or guard disposed on the first end of the plunger rod. A plunger head extends within the chamber of the syringe barrel, and is adapted for slidable movement within the syringe barrel between the proximal end and the distal end, with the second end of the plunger rod connected with the plunger head through a pivotable connection. The plunger rod is adapted to pivot with respect to the plunger head between a first position in which the guard is adjacent the distal end of the syringe barrel and a second position in which the plunger rod is in general axial alignment with the syringe barrel, and is further adapted for axial movement so as to cause sliding movement of the plunger head through the syringe barrel to expel the contents thereof. | 02-24-2011 |
20110046604 | Syringe Assembly with Inverse Delivery - A reduced profile syringe assembly is provided that includes an overall profile that is substantially similar to the profile of the syringe barrel. The syringe assembly includes a plunger rod that is significantly disposed within the syringe barrel when filled for use, with the plunger rod adapted to be retracted from the syringe barrel during dispensing of the contents of the syringe barrel. | 02-24-2011 |
20110046605 | NEEDLE SHEATHING DEVICE WITH FLEXIBLE END-PIECE FOR SYRINGE - The invention relates to a safe support device for a syringe, said support comprising a support sheath for the body of a syringe, and safety means which comprise an inner sheath suitable for sliding relative to said support sheath between a waiting retracted position, in which said inner sheath is substantially retracted inside said support sheath, and an active protection position, in which said inner sheath projects from said support sheath. The inner sheath has a free end portion formed by a flexible end-piece. The invention also relates to an assembly comprising such a safe support device and a syringe having a body, a piston and a needle disposed at one end of said body. | 02-24-2011 |
20110046606 | Catheter injectable depot compositions and uses thereof - Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions are have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection. | 02-24-2011 |
20110054440 | DISINFECTING MALE LUER CONNECTOR CAPS - A system and method for disinfecting an exposed portion of a female luer connector is disclosed. A male luer connector coupled to a male luer connector cap is provided where the male luer connector cap has a chamber containing a disinfectant and a sealing member for sealing the disinfectant in the chamber. The chamber is at least partly opened and the disinfectant exposed by movement of the sealing member. An exposed surface of a female luer connector is caused to come in contact with the disinfecting fluid in the chamber prior to the female luer connector mating with the male luer connector. | 03-03-2011 |
20110054441 | METHODS, DEVICES, AND COMPOSITIONS FOR INTRAVITREAL INJECTION - Methods of treating disorders of the eye are disclosed. One or more substances are injected into the vitreous humor of the eye using a syringe. A needle of the syringe is inserted into the eye such that the tip of the needle is positioned inferior to the visual axis. The needle of the syringe is inserted into the eye at an injection point that is located from 3 mm to 5 mm posterior to the limbus of the eye. The tip of the needle is positioned at a depth from 1 mm to 10 mm from the retina of the eye at the injection point. | 03-03-2011 |
20110054442 | Cell Membrane Translocation of Regulated Snare Inhibitors, Compositions Therefor, and Methods for Treatment of Disease - Compositions and methods of modulating cellular function and treatment of disease in mammals comprising locally administering a regulated SNARE inhibitor and a translocating agent to the mammal. Regulated SNARE inhibitors include clostridial neurotoxins, tetanus neurotoxin and their free light chain portions and IgA protease. Translocating agents include acids, encapsulating vectors, and transduction domains. | 03-03-2011 |
20110060310 | INTRACUTANEOUS INJECTION - The delivery of biopharmaceutical and other therapeutic agents parenterally to an animal via a minimally invasive, low pain administration is provided. The agents are delivered to the patient via, e.g., the epidermal, dermal, or subcutaneous layer of the skin in a concentrated fours of injectable paste of slurry. | 03-10-2011 |
20110066135 | SINUS DELIVERY OF SUSTAINED RELEASE THERAPEUTICS - The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers. | 03-17-2011 |
20110071492 | HUB ASSEMBLY HAVING A HIDDEN NEEDLE FOR A DRUG DELIVERY PEN - A hub assembly for a pen injection device prevents a patient from seeing a needle of a hub assembly during an injection. A hub is connected to the pen injection device. A needle is received by the hub. A compressible member is connected to the hub and is compressible between a first position that entirely covers said needle and a second position that exposes the needle for an injection. | 03-24-2011 |
20110071493 | Flow-Induced Delivery from a Drug Mass - Drug solutions (or other combinations of vehicle with entrained drug) are prepared by removing drug from one or more masses of a solid form of the drug. The solid form of the drug may be sparingly soluble or insoluble in water. Examples of devices for holding solid drug and facilitating delivery of such drug to targeted regions are also described. | 03-24-2011 |
20110071494 | Intradermal Delivery Device - A system and method is provided for an injectable substance delivery device comprising a limiter, shoulder or post, that controls how deep the needle is inserted into the tissue. The limiter is sized in proportions that control the maximum insertion depth of the needle into the tissue without excessively restricting the complete insertion of the needle. The system and method further comprises an normalization or stabilizer ring that prevents distortion of the tissue in the vicinity of the infusion, so that the needle length is the major determining factor as to how deep the infusion is delivered. | 03-24-2011 |
20110077617 | Device for implanting objects into animal tissue - A device for implanting an object into animal tissue and a method for using the same device is provided. The device includes a cannula having a longitudinal axis, a passageway extending therethrough, a proximal end, and an opposite distal end that is insertable into tissue and defines an exit aperture for discharge of the object from the cannula. The device also includes an axially movable plunger disposed and oriented in a non-coaxial relationship within at least a portion of the cannula and a partial barrier disposed within the cannula adjacent to its distal end and configured to at least partially block the passageway, where the partial barrier at least partially defining an object receiving opening that is in communication with the passageway and sufficiently sized to receive the object and the plunger. When the device is in a first position, the partial barrier prevents the object from entering the passageway even when the plunger is inserted into the object receiving opening. When the device is moved to a second position, the passageway is aligned with the object, such that, upon movement of the plunger towards the distal end of the cannula, the plunger engages the object and pushes it through the object receiving opening towards and through the exit aperture. | 03-31-2011 |
20110077618 | Methods and Compositions for Treating Post-Cardial Infarction Damage - Methods and compositions for treating post-myocardial infarction damage are herein disclosed. In some embodiments, a carrier with a treatment agent may be fabricated. The carrier can be formulated from a bioerodable, sustained-release substance. The resultant loaded carrier may then be suspended in at least one component of a two-component matrix system for simultaneous delivery to a post-myocardial infarction treatment area. | 03-31-2011 |
20110082441 | Bone Marrow Aspiration Needle - Disclosed is an aspiration assembly including an outer cannulated needle having a tip, a threaded collar, and an inner aspiration needle. A material can be aspirated through at least the inner aspiration needle. The distance that the tip of the inner aspiration needle extends from the tip of the outer cannulated needle changes when the inner aspiration needle is rotated relative to the outer cannulated needle. | 04-07-2011 |
20110087189 | CONTROLLED DELIVERY OF SUBSTANCES SYSTEM AND METHOD - A fluid infusion system is described. Certain embodiments include an infusion syringe assessment device that assesses one or more characteristics of an infusion syringe coupled to a fluid infusion pump during use. The system may include a fluid infusion pump configured to accept the infusion syringe. The fluid infusion pump may advance an infusion fluid to a test subject in accordance with an infusion routine based on one or more of the assessed characteristics of the infusion syringe. The infusion routine may include at least one rate, at least one volume, at least one start time, at least one end time, and/or at least one duration. | 04-14-2011 |
20110092952 | Shield Apparatuses and Methods For Storing Syringe Assemblies and Needle Assemblies - The present invention is directed to shield apparatuses configured to hold syringe assemblies in a manner that preserves their ease of use and convenience. In some embodiments, the syringe assemblies are detachable, and the shield apparatuses provide for convenient interchanging of the needle assemblies, as well as methods for administering injections to a patient. | 04-21-2011 |
20110092953 | Flowable Carrier Matrix - A carrier matrix may be delivered to a target position within a patient in a minimally invasive manner by first cutting a collagen sponge sheet into a plurality of relatively small pieces. These pieces are sized so that, when wet, they are capable of flowing through a cannula and/or reduced-diameter syringe tip. The pieces are placed into a syringe and wetted, say with a morphogenic solution, and optionally mixed with a bulking material, which is similarly sized to fit through the cannula. The thoroughly mixed and wetted product forms a viscous aggregate which may then be injected into the patient at the target site. | 04-21-2011 |
20110092954 | Reusable Auto-Injector - An injection device comprises a first sub-assembly comprising a chamber for holding a fluid and a transfer assembly moveably disposed within the chamber. The chamber comprises an exit aperture and an inner surface and the transfer assembly has an outer surface substantially in contact with the inner surface about its perimeter. The transfer assembly is adapted to transfer fluid into the chamber when the transfer assembly is moved within the chamber. | 04-21-2011 |
20110098675 | DEVICE FOR INJECTING A SOLID | 04-28-2011 |
20110112507 | CURABLE MATERIAL DELIVERY SYSTEMS AND METHODS - A distal end of a cannula immediately proximate a target site within bone. A portion of a cavity-forming device is extended through the cannula and distally beyond the distal end, and then operated to form a cavity at the target site. A track is defined in tissue of the target site between the distal end of the cannula and the cavity. The cavity-forming device is removed from the cannula, and replaced with a delivery tube. A distal tip of the delivery tube is directed distally beyond the distal end of the cannula, through the track and into the cavity. Finally, a material (e.g., a curable material) is delivered through the delivery tube and into the cavity. The cannula can remain stationary following initial insertion, and curable material is not directly deposited into the normally occurring “dead space”. | 05-12-2011 |
20110112508 | Drug Delivery Devices, Systems, and Methods - This disclosure relates to drug delivery devices, systems, and methods. In some aspects, a drug delivery device includes an elongate member defining a fluid passage and an opening in fluid communication with the fluid passage, and a projection extending radially from the elongate member. A portion of the elongate member extending axially from the projection to a distal end of the elongate member has a length sufficient to allow the distal end of the elongate member to reach subdermal tissue of a patient when the elongate member is inserted into the patient and the projection is in contact with an outer surface of skin of the patient, and the opening is positioned at a location along the elongate member such that the opening is disposed within a dermis of the patient when the elongate member is inserted into the patient and the projection is in contact with the outer surface of the skin of the patient. | 05-12-2011 |
20110112509 | MICRONEEDLE DEVICE, AND METHOD FOR ENHANCING THE EFFICACY OF INFLUENZA VACCINE BY USING MICRONEEDLE DEVICE - The present invention provides a method for enhancing the immunogenicity using a microneedle device capable of enhancing the immunogenicity of an influenza vaccine. According to the method for enhancing the immunogenicity using the present microneedle device, a microneedle device having microneedles made of polylactic acid, coated with an influenza vaccine composed of an antigen having type A strain (H1N1), type A strain (H3N2), and type B strain as active ingredients is brought into direct contact with the skin so as to transcutaneously administer the aforementioned influenza vaccine. After the transcutaneous administration, lauryl alcohol is applied to the site of the skin where the microneedle device has been brought into direct contact. | 05-12-2011 |
20110118700 | ADMINISTRATION DEVICE COMPRISING INDICATION UNIT AND METHOD FOR SETTING A DOSE - An administration device for the administration of a liquid drug in adjustable doses may comprise an injection unit and an electronic indication unit. The injection unit may comprise a dosing mechanism and a manually operated dose setting component. The manually operated dose setting component may adjust the dosing mechanism to administer an administration dose amount of the liquid drug. The electronic indication unit may indicate a relationship between the administration dose amount and a target dose amount. A method for setting a dose of a liquid drug for administration may comprise providing an administration device, operating a manually operated dose setting component of the administration device, and continuing to operate the dose setting component until an electronic indication unit indicates that the administration dose amount is equal to the target dose amount. | 05-19-2011 |
20110118701 | Dose Dividing Delivery Device - A simple method and device enabling a unit dose from a reservoir is provided. The dose is drawn into the reservoir and is then expelled from the device by depressing the plunger. The plunger ( | 05-19-2011 |
20110118702 | DEVICE FOR LOCATING EPIDURAL SPACE WHILE SAFEGUARDING AGAINST DURAL PUNCTURE THROUGH DIFFERENTIAL FRICTION TECHNIQUE - A device for locating a cavity within two walls including a syringe including a syringe piston slideable in a first syringe barrel for discharging air or fluid contained in the first syringe barrel on forward movement of the syringe piston into the cavity, the first syringe barrel being attached to a hub of a needle cannula; and a frame which at least in part encases the syringe and which is solely connected to the back of the syringe piston. | 05-19-2011 |
20110125130 | RETRACTABLE NEEDLE ASSEMBLY AND SYRINGE UTILIZING THE SAME - An injection device including a barrel, a hollow plunger having a portion structured and arranged to move within the barrel, a needle unit, and a safety system that one of automatically causes the needle unit to retract into the plunger when the plunger reaches a substantially fully depressed position. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way. | 05-26-2011 |
20110130743 | Re-Useable Auto-Injector with Filling Means - An injection device having a first sub-assembly comprises a housing and a chamber. The chamber is disposed within the housing and has proximal and distal ends, an inner surface and an exit aperture. The sub-assembly comprises a stopper movably disposed within the chamber. The stopper has an outer surface substantially in contact with the inner surface about its perimeter. The sub-assembly comprises a port adapted to receive a container containing a fluid. The stopper is fixed with respect to the housing and movement of the port causes movement of the exit aperture in relation to the stopper. | 06-02-2011 |
20110137285 | KIT OF TAMPONING LIQUIDS AND A METHOD FOR THE TREATMENT OF TEARS AND/OR DETACHMENTS OF THE RETINA USING SUCH LIQUIDS - A kit of tamponing liquids comprising a first liquid having a density lower than 1.00 g/cm | 06-09-2011 |
20110137286 | INJECTION DEVICE FOR SOFT-TISSUE AUGMENTATION FILLERS, BIOACTIVE AGENTS AND OTHER BIOCOMPATIBLE MATERIALS IN LIQUID OR GEL FORM - Described herein are injection devices capable of automatically injecting substances into the soft tissue of a patient. The devices can inject low to high viscosity materials at predetermined, user selected injection rates, allowing the operator more control than a traditional syringe. The devices can allow mixing of more than one substance and/or reconstitution of a solid substance for injection. The injection devices described herein can allow the operator to easily inject one or more low to high viscosity liquid or gel soft-tissue augmentation fillers, one or more drugs, one or more other biocompatible materials, or combinations thereof. | 06-09-2011 |
20110137287 | MULTI-CARTRIDGE FLUID DELIVERY DEVICE - A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments. | 06-09-2011 |
20110144619 | MEMS DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS - Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid communication with the reservoir. A valve for maintaining a constant flow rate through the cannula independent of the pressure applied to the device may be included. | 06-16-2011 |
20110152831 | Peristaltic Pump with Linear Flow Control - A peristaltic pump includes a conduit having a first end for receiving a fluid from a reservoir and a second end for delivering the fluid. A plurality of fingers are disposed at respective locations along a segment of the conduit and are configured to alternately compress and release the conduit at the locations. A cyclical pump mechanism is coupled to move the fingers between respective compressed and released positions in a spatio-temporal pattern so as to drive a predetermined quantity of the fluid through the segment of the conduit in each pump cycle. A motor is coupled to drive the pump mechanism. A controller is coupled to activate and deactivate the motor in alternation during each pump cycle with a duty cycle that varies within the pump cycle. | 06-23-2011 |
20110152832 | NEEDLE SAFETY MECHANISM - A syringe needle safety apparatus comprising a syringe barrel having an open end and an opposite end adapted for a needle and a needle safety cover displaceable between a un-deployed state wherein the cover is constrained and the needle exposed, and a deployed state wherein the cover covers at least the needle tip. A plunger is slidably engaged in the syringe barrel and at least one element secures the needle safety cover in the un-deployed state. Biasing means urge the needle safety cover from the un-deployed state to the deployed state, and a housing is coupled to the opposite end of the syringe barrel, the housing comprising a corresponding securing member and a deformable member, the deformable member releasing the at least one element from the corresponding securing member upon receiving a releasing force via the plunger. During deployment, the needle safety mechanism provides for the needle safety cover to avoid contact with the needle, reducing or eliminating blood contact. | 06-23-2011 |
20110152833 | APPARATUS AND METHODS FOR TREATING TISSUE USING PASSIVE INJECTION SYSTEMS - Methods and apparatus are provided for treating damaged tissue using apparatus that atraumatically delivers a bioactive agent within the tissue, wherein the apparatus provides a column of stem cells may be advanced simultaneously with a needle during needle insertion, and then held stationary or injected at low pressure while retracting the needle. Alternatively, the needle may employ electromotive forces, or to change a dimension of the needle, to expel the bioactive agent into the needle track. | 06-23-2011 |
20110152834 | SAFETY DEVICE FOR DRUG DELIVERY DEVICES AND CONTAINERS - A drug administration safety device having a label configured to be attached to a drug container such as a syringe or IV bag, an adhesive on the back face of the label, and a backing or substrate for holding the label and protecting the adhesive prior to the application of the label to the drug container. In one embodiment, the label includes a first drug name section in a first orientation, a second drug name section in a second orientation, a third drug name section in a third orientation, a drug concentration section, a variable information section, and a gradiation viewing section. The first orientation, second orientation, and third orientation are different from each other to enable a user to readily see the drug name regardless of the position and orientation of the drug container. | 06-23-2011 |
20110160696 | INJECTION PORT DEVICE ADAPTED FOR USE WITH INSULIN PUMP - An injection port comprises a body having an outlet delivery cannula configured to pierce subcutaneous tissue of a patient to deliver medication. The port includes multiple injection sites, each of which can be used multiple times, and each of which is sealed. Each injection port is configured to temporarily receive a delivery device and reseal itself when the delivery device is removed. In one embodiment, a seal includes a pierceable stationary septum that reseals itself when a sharp cannula is removed. One injection site also includes locking features to receive a locking device of a delivery device and temporarily lock the delivery device in place at the injection site. The locking device may later be unlocked when delivery is complete and removed. In one application, a diabetic may use one injection site for syringes during the day and the locking injection site for a insulin pump during sleeping hours. | 06-30-2011 |
20110160697 | DEVICE AND METHOD FOR ENHANCED SUBCUTANEOUS INSULIN ABSORPTION - Products and methods directed to the improved infusion of fluids are disclosed. Such products and methods can be used to more efficiently and efficaciously administer therapeutic pharmaceuticals to a subject in need of treatment. In many instances, the systems comprise a therapeutic fluid delivery system and a mechanism for enhancing the absorption of the therapeutic fluid. The enhancement of the absorption of the therapeutic fluid is generally performed locally i.e., at or near the site of administration of the therapeutic fluid. The system and methods can be used to deliver any number of therapeutic fluids including but not limited to insulin. | 06-30-2011 |
20110172636 | INJECTION APPARATUS AND SPECIAL NEEDLE FOR MAKING AN INJECTION AT A PREDETERMINED DEPTH IN THE SKIN - An injection apparatus for making an injection at a predetermined depth in skin comprises: a skin positioning member, an injection needle ( | 07-14-2011 |
20110172637 | DRUG DELIVERY DEVICE INCLUDING TISSUE SUPPORT STRUCTURE - A drug delivery device for delivering a drug to a subject includes a microneedle configured to facilitate delivery of the drug to the subject. The microneedle includes a tip portion and is moveable from an inactive position to an activated position. When the microneedle is moved to the activated position, the tip portion of the microneedle is configured to penetrate the skin of the subject. The drug delivery device includes a tissue support structure that includes a channel and an engagement element. The channel has a first end and a second end and is in axial alignment with the microneedle. At least the tip portion of the microneedle extends past the second end of the channel in the activated position. The engagement element is positioned adjacent to the channel, and the engagement element is configured to engage with the skin of the subject such that the engagement element resists downward deformation of the skin caused by the microneedle as the microneedle moves from the inactive position to the activated position. | 07-14-2011 |
20110172638 | DRUG DELIVERY DEVICE INCLUDING MULTI-FUNCTIONAL COVER - An apparatus for delivering a drug to a subject is provided. The apparatus includes a housing, a microneedle coupled to the housing and configured to extend from the housing when activated, an activation control coupled to the housing and an outer shell. The outer shell includes a top wall having an inner surface and a sidewall extending from the top wall, the sidewall having an inner surface. The outer shell includes a first attachment structure configured to attach to the housing. The outer shell covers the activation control when the first attachment structure is attached to the housing. The outer shell includes a second attachment structure configured to attach to the housing. The outer shell covers the activated microneedle when the second attachment structure is attached to the housing. | 07-14-2011 |
20110172639 | DEVICE AND METHOD FOR DELIVERY OF MICRONEEDLE TO DESIRED DEPTH WITHIN THE SKIN - A device for delivering a drug into the skin of a subject is provided. The device includes a drug reservoir and a microneedle having a tip, a length, and a tip sharpness. The microneedle is coupled to the reservoir. The device includes a microneedle actuator coupled to the microneedle configured to drive the microneedle into the skin of the subject upon activation. The tip sharpness and the actuator allow the microneedle to pass through an outer layer of the skin upon activation, and the length is limited such that the tip does not extend past a desired depth below the surface of the skin of the subject, wherein the desired depth is located in the papillary dermis or the reticular dermis. | 07-14-2011 |
20110172640 | Medical injector with ratcheting plunger - A medical injector has a body with a displaceable plunger. The plunger includes a plurality of spaced-apart ratchet teeth disposed along the length thereof. At least one indexer is provided to engage the plunger, wherein the indexer is configured to allow the plunger to displace distally toward a distal end of the body but not proximally toward a proximal end of the body. The medical injector also includes an actuator having an engagement portion formed to engage one or more of the ratchet teeth. The actuator is displaceable to a ready state, the engagement portion being displaced proximally relative to the plunger with the actuator being displaced to the ready state. The indexer prevents proximal movement of the plunger, thereby allowing the engagement portion to bypass one or more of the ratchet teeth with the actuator being displaced to the ready state. In addition, the actuator is displaceable from the ready state to cause actuation of the medical injector. The displacement from the ready state causes distal displacement of the engagement portion with the engagement portion engaging one or more of the ratchet teeth and causing distal displacement of the plunger with the engagement portion. | 07-14-2011 |
20110178500 | FIRING BUTTON FOR AUTOMATIC INJECTION DEVICE - Exemplary embodiments provide firing mechanism assemblies that minimize or eliminate a misfire of an automatic injection device that causes a delay in the delivery of an injection. Exemplary embodiments provide automatic injection devices including firing mechanism assemblies that minimize or eliminate a misfire that causes a delay in the delivery of an injection. Exemplary embodiments provide methods for minimizing or eliminating misfire that causes a delay in delivery of an injection in automatic injection devices. Exemplary embodiments provide methods for using automatic injection devices that are free of a misfire that causes delay in delivery of a therapeutic substance into a patient's body. | 07-21-2011 |
20110178501 | AUTOINJECTOR - An autoinjector including a housing, in which can be mounted a syringe having a plunger, a barrel and needle at one end thereof through which medicament can be delivered to an injection site; a syringe support means capable of causing said syringe to move therewith along an axial path with respect to said housing; biasing means capable of biasing said syringe support means so that said needle is normally inside said housing, blocking means selectively moveable by a user from a first position in which rearward movement of the syringe along said axial path is substantially prevented, to a second position in which rearward movement of the syringe along said axial path relative to said housing is possible and said biasing means causes said needle to retract inside said housing. | 07-21-2011 |
20110178502 | CELL THERAPY FOR LIMITING OVERZEALOUS INFLAMMATORY REACTIONS IN TISSUE HEALING - Cells of the B cell lineage including pre-pro-B cells, pro-B cells, pre-B cells, immature B cells, and some mature B cells, and/or cells of the T cell lineage, especially those with helper or regulatory function, most preferably autologous to the recipient, can be transplanted into damaged tissue to enhance recovery following injury. In a preferred embodiment, the cells are selected based on those cells which appear at the site of injury a few days after injury, such as macrophages, lymphocytes, which accelerate clean up and repair of the injured site and to mitigate the overzealous inflammatory response, presumably by inhibiting the inflammatory cells such as neutrophils and signals released thereby immediately following injury. | 07-21-2011 |
20110184381 | REPAIR OF DEFECTS OR LESIONS IN CARTILAGE AND BONE USING A CHONDRO-REGULATIVE MATRIX - Methods and compositions are provided for the treatment and repair of defect in the cartilage in partial- or full-thickness defects in joints of animals, in particular humans. To induce cartilage formation, a defect in cartilage is filled with layers of thin flaps of synovium or of peritendineum, which contains chondro- and osteo-progenitor cells, with interposed layers of a matrix. The matrix contains a chondrogenic factor, which induces chondrogenesis of chondroprogenitor cells in the flaps, and an anti-hypertrophic agent, which arrest differentiation of chondrocytes in an early phase, in an appropriate delivery system. The matrix filling the bone area of a full-thickness defect may contain an osteogenic factor, which induces osteogenesis of osteoprogenitor cells. The layer of a flap between cartilage and bone areas may work as a barrier, which prevents blood vessels and associated cells from penetrating from the bone area into the cartilage area. To promote the induction of chondro- and osteo-genesis of the progenitor cells in the flaps of synovium or peritendineum effectively, the flaps may be treated with enzymes, e.g., matrix metalloproteinases or be punched by a needle before filling a defect. | 07-28-2011 |
20110184382 | MULTI-PURPOSE ARTICLES FOR SANITIZING AND CAPPING LUER ACCESS VALVES - Multi-purpose devices for capping fluid reservoirs and sanitizing accessible surfaces of fluid-transporting medical fittings (e.g., luer access valves) at risk of contamination with infectious agents are described, as are methods for making and using such devices. | 07-28-2011 |
20110184383 | SYRINGE PUMP - A syringe pump includes: a syringe mounting part on which to mount a syringe outer cylinder of a syringe; a clamp which is pulled downward by an elastic member, contacts an upper surface of the mounted syringe outer cylinder and thereby fix the syringe outer cylinder; a slider which holds a plunger flange of a plunger of the mounted syringe by levers and which pushes out the plunger; and a display or monitor of which the display is controlled by the computer. Regarding an operation of mounting the syringe outer cylinder onto the syringe mounting part, an operation of setting the plunger flange into the slider, and an operation of fixing the syringe outer cylinder with the clamp, the display or monitor alternately displays the respective states before and after the operations at a predetermined interval. | 07-28-2011 |
20110190725 | METHOD FOR ALTERING DRUG PHARMACOKINETICS BASED ON MEDICAL DELIVERY PLATFORM - A method for directly delivering whereby a substance is introduced into an intradermal space within mammalian skin which involves administering the substance through at least one small gauge hollow needle having an outlet with an exposed height between 0 and 1 mm. The outlet is inserted into the skin to a depth of between 0.3 mm and 2 mm such that the delivery of the substance occurs at a depth between 0.3 mm and 2 mm. | 08-04-2011 |
20110190726 | Method and apparatus for micro-needle array electrode treatment of tissue - Systems and methods for revitalizing aging skin using electromagnetic energy that is delivered using a plurality of needles that are capable of penetrating the skin to desired depths. A particular aspect is the capability to spare zones of tissue from thermal exposure. This sparing of tissue allows new tissue to be regenerated while the heat treatment can shrink the collagen and tighten the underlying structures. Additionally, the system is capable of delivering therapeutically beneficial substances either through the penetrating needles or through channels that have been created by the penetration of the needles. | 08-04-2011 |
20110196337 | Modular Drug Delivery Device for Administering Discrete Doses of a Medicament - There provided a drug delivery device adapted for providing a plurality of discrete doses of a medicament including a disposable delivery unit ( | 08-11-2011 |
20110196338 | CLOSURE CONTAINER FOR SINGLE DOSE DISPOSABLE PHARMACEUTICAL DELIVERY SYSTEM - Provided herein is a single dose disposable pharmaceutical delivery apparatus and methods of use and manufacture thereof. One aspect provides a single dose disposable pharmaceutical delivery apparatus that includes a needle hub seal attached to a needle hub and a bladder that can contain a pharmaceutical composition. Another aspect provides for dispensing a pharmaceutical composition from the delivery apparatus by rupturing the needle hub seal and fluidically connecting the needle and the bladder. Another aspect provides manufacturing the delivery apparatus according to steps including attaching a needle hub and a needle hub seal and combining the bladder and the needle hub, thereby forming an apparatus described herein. | 08-11-2011 |
20110196339 | AUTOMATIC INJECTION DEVICE FOR ADMINISTERING A FIXED DOSE - An injection device for administering a substance, including a housing, a plunger rod which can be moved relative to the housing, at least one retaining element associated with the rod to hold the rod relative to the housing, and a displaceable locking sleeve which can be displaced relative to the housing from one position in which the sleeve holds the at least one retaining element in a retaining position to a second position in which the at least one retaining element is released. | 08-11-2011 |
20110202034 | MODULAR MEDICAL FLUID HEATING APPARATUS - A controller and a plurality of concatenated heating modules in electrical communication with the controller. The controller controls the flow of current to the plurality of heating modules in response to temperature measurements from at least one of the plurality of heating modules. In one embodiment, each of the plurality of heating modules concatenated with another heating module is connected by Luer-Lok™ connectors. In another embodiment, the modular medical fluid heating system further includes an auxiliary heating unit in electrical communication with the controller and in physical juxtaposition with the plurality of heating modules. The invention also relates to a heating module for a modular medical fluid heating system including a fluid input port; a fluid output port; and serpentine tubing through which fluid passes from the fluid input port to the fluid output port. In one embodiment, the heating module can be concatenated with other heating modules. | 08-18-2011 |
20110202035 | Syringe Assemblies Having Detachable Needle Assemblies and Low Dead Space - The present invention is directed to syringe assemblies comprising detachable needle assemblies, that are configured in such a manner as to minimize the dead space after deployment of the syringe piston and injection of the material in the syringe into a patient's body, as well as with bevel indicators that provide guidance as to optimal angles at which to inject the needles into patients. | 08-18-2011 |
20110208157 | NEEDLE CONSTRUCTED WITH A TRANSPARENT OR TRANSLUCENT MATERIAL - In general, the invention features needles, with or without lumens, that contain a barrel being transparent or translucent or having a transparent or translucent portion. Needles of the invention may further include a lumen, the interior of which is visualizable through the transparent or translucent portion. A needle may also include a portion to which a suture is capable of being attached. | 08-25-2011 |
20110208158 | Apparatus and Method for Endoscopic Submucosal Dissection - A kit and a method for delivering an injectable solution to a tissue treatment site are provided. The kit includes a housing having a chamber, a proximal portion and a distal portion. An injectable solution having a viscosity greater than about 10,000 cP is provided in the chamber. A plunger is provided in the proximal portion of the housing. The kit also includes a pressure gauge operably connected to the housing. The kit may also include a handle connected to the housing and a plunger advancing member having a plunger handle connected thereto provided separate from the housing. The kit may also include an inner shaft provided separate from the housing and having a proximal end portion configured for operably connecting with the distal portion of the housing for receiving the injectable solution therethrough and a distal end of the shaft configured for insertion in to the tissue treatment site. | 08-25-2011 |
20110213333 | Hollow Curved Superelastic Medical Needle And Method - A needle assembly | 09-01-2011 |
20110213334 | SAFETY ASSEMBLY FOR A SYRINGE - A safety support device for a syringe comprises a support sheath ( | 09-01-2011 |
20110213335 | HOLLOW MICRONEEDLE ARRAY AND METHOD - Rapid, high-volume, intradermal infusion with minimal pain, is achived by applying an array of 10 to 30 hollow microneedles having a length of greater than 100 um to less than 1 mm into the skin of a patient, with a microneedle spacing of no less than 1.5 mm on average between adjacent microneedles, and pumping greater than 200 uL of fluid through the hollow microneedles at a rate of greater than 20 uL/min. | 09-01-2011 |
20110224647 | BODY CAVITY DRAINAGE DEVICES AND RELATED METHODS - Body cavity drainage devices and associated methods are disclosed herein. In some embodiments a body cavity drainage device comprises a drainage tube having a proximal end and a distal end; and an automated means to move the distal end of the drainage tube about a body cavity of a patient. In some embodiments, the distal end of the drainage tube may be moved by one or more of the application of a magnetic field, the insertion or withdrawal of fluid from a closed lumen, and manipulation by an external motion generator. In additional embodiments, a body cavity drainage device includes at least a second open lumen for the insertion of a fluid into a body cavity. In yet further embodiments, an internal tissue may be massaged from within a body cavity of a patient. | 09-15-2011 |
20110238036 | SUSTAINED RELEASE DELIVERY DEVICES - An injectable drug delivery device includes a core containing one or more drugs and one or more polymers. The core may be surrounded by one or more polymer outer layers (referred to herein as “coatings,” “skins,” or “outer layers”). In certain embodiments, the device is formed by extruding or otherwise preforming a polymeric skin for a drug core. The drug core may be co-extruded with the skin, or inserted into the skin after the skin has been extruded, and possibly cured. In other embodiments, the drug core may be coated with one or more polymer coatings. These techniques may be usefully applied to fabricate devices having a wide array of drug formulations and skins that can be selected to control the release rate profile and various other properties of the drugs in the drug core in a form suitable for injection using standard or non-standard gauge needles. | 09-29-2011 |
20110238037 | GAS-PRESSURED MEDICATION DELIVERY DEVICE - The present invention relates to medical devices and particularly to a medication delivery device for self-injection of a medication, or for healthcare professionals to administer a medication. In one embodiment, a medication delivery device utilizes a source of gas pressure to deploy a needle, deliver a desired amount of medication through the needle, and retract the needle for disposal. Fluid flow paths from the source of gas pressure communicate the gas pressure to the needle and to the medication in order to accomplish these steps. In one embodiment, a valve is positioned to open and close the flow of the pressurized gas to the needle and the flow of the medication to the needle, so that the valve can be operated to deploy the needle and deliver the medication through the needle when the user is ready for the injection. The valve can also be operated to retract the needle when the dose is complete. | 09-29-2011 |
20110238038 | INTRADERMAL MINI - NEEDLE INTERFACE AND ASSOCIATED DEVICES AND METHODS - An intradermal mini-needle interface has a penetration limiter providing a skin contact edge and a hollow hypodermic needle having a beveled penetrating portion protruding forward beyond the skin contact edge by no more than 3 mm. At least one skin contact surface defines a skin contact plane parallel to, or at a shallow angle to, the needle axis. The skin contact plane intersects the skin contact edge substantially at a base of the penetrating portion. Preferably, the penetration limiter is asymmetric under rotation about the needle axis. | 09-29-2011 |
20110245799 | SYSTEM AND METHOD FOR DELIVERY OF SUSPENSIONS AND OTHER MICROPARTICLE COMPOSITIONS - Disclosed herein are systems and methods useful for delivery of suspensions and other microparticle compositions, and, in particular, for delivering microparticles at desired dosing levels and eliminating blockages within microparticle suspensions positioned within a delivery device. | 10-06-2011 |
20110245800 | DEVICES, SYSTEMS, AND METHODS FOR TRANSEPTAL ATRIAL PUNCTURE USING AN ENGAGEMENT CATHETER PLATFORM - Multichannel systems for engaging a bodily tissue and methods of using the same. In at least one embodiment of an exemplary multichannel system for engaging a tissue of the present disclosure, the system comprises an engagement catheter comprising a proximal end, a distal end, and defining a first lumen and second lumen extending between the proximal end and the distal end, an inducer sheath having a proximal portion and a distal portion, and defining a lumen extending therethrough, the inducer sheath configured for insertion into the second lumen of the engagement catheter, and a dilator defining a first channel and a second channel extending therethrough and a tapered tip at the distal end of the dilator, the dilator sized and shaped for inserted into the lumen of the inducer sheath. | 10-06-2011 |
20110245801 | IMMOBILIZING OBJECTS IN THE BODY - Stabilizing an object in the body of a patient involves the injection of a lower critical solution temperature (LCST) material or other flowable material into the body of the patient so that the material contacts the object. The LCST material or other flowable material then forms a gel in the body such that the object is contained at least partially within the gel and thereby stabilized by the gel such that the object can then be easily fragmented within the body and/or retrieved from the body. | 10-06-2011 |
20110251585 | Sub-mucosal agent delivery, apparatus, system and method - An agent delivery apparatus for administering a pharmacological agent formulation to a sub-mucosal compartment of a body organ, comprising injector means having an internal formulation chamber that is adapted to receive and contain the pharmacological agent formulation therein and an elongated agent delivery member having a first end that is in communication with the internal formulation chamber and a second ejection end, the injector means including force generating means that is adapted to generate sufficient force to expel the pharmacological agent formulation from the injector means and into and through the agent delivery member, and out of the ejection end of the elongated agent delivery member. In one embodiment of the invention, the delivery-member comprises a needleless delivery member. | 10-13-2011 |
20110251586 | Subconjunctival agent delivery apparatus, system and method - A subconjunctival injection apparatus for administering a pharmacological agent formulation to a subconjunctival compartment of an eye, the apparatus including a jet injector having force generating means that is adapted to generate sufficient force to expel the pharmacological agent formulation from the jet injector and through the conjunctiva. In one embodiment of the invention, the jet injector comprises a needleless jet injector. In one embodiment, the needleless jet injector provides a delivery pressure in the range of approximately 100-1000 psi. | 10-13-2011 |
20110251587 | Syringe Housing To Facilitate Medication Injection - A syringe ( | 10-13-2011 |
20110257628 | INSTRUMENT FOR ALLEVIATING ADDICTIVE DRUG CRAVING, METHOD FOR USING SAME AND METHOD FOR TREATING ADDICTIVE DRUG DEPENDENCE - Provided is an instrument for alleviating addictive drug craving which can be safely administered to an addictive drug-dependent patient by a definite method in practice without causing any undesirable effects on therapy and terminate a series of behaviors through the administration so as to achieve an excellent effect on the therapy for alleviating addictive drug craving. An instrument for alleviating addictive drug craving ( | 10-20-2011 |
20110264072 | TRANSSEPTAL ACCESS DEVICE AND METHOD OF USE - Systems, devices, and methods are provided for transseptal access of septa within a patient. The device can be advanced to a septum, e.g., towards a fossa ovalis. Instead of applying positive pressure to “tent” the septum, a negative pressure is applied to a lumen within a sheath, e.g., within an elongated member slidable within the sheath, via a negative pressure source such as a syringe on the proximal end of the sheath. This results in the septum pulling inward. The sheath employs a stationary needle-like central core component contained within the lumen of the sheath that punctures the septum when the same is pulled passed it by the negative pressure. The stationary needle-like central core component may be hollow and may form a portion of the elongated member or may be coupled to a distal end thereof. | 10-27-2011 |
20110270219 | ADMINISTRATION DEVICE HAVING A BUTTON WITH TOUCH SENSOR - Administration devices for supplying an injectable or infusible product into an organism include a reservoir for storing the product, a supply device for supplying the product from the reservoir into the organism, a controller to control operation of the administration device, a button communicatively coupled to the controller to initiate at least one action of the administration device and a touch sensor that generates an activation signal, wherein the touch sensor is incorporated into the button or is disposed in the vicinity of the button and is communicatively coupled to the button and/or the controller. | 11-03-2011 |
20110270220 | LINEARLY ACTUATED DISPENSER AND THERAPEUTIC PACKAGE SUITABLE FOR ADMINISTERING A THERAPEUTIC SUBSTANCE AND RELATED METHOD - A device for administering a therapeutic substance includes a sealed package and an administration assembly. The sealed package includes a collapsible compartment containing the substance. The administration assembly includes a dispenser that is in fluid communication with the substance. At least one compression member is movable by linear actuation to progressively collapse the collapsible compartment and urge the therapeutic substance through the dispenser. | 11-03-2011 |
20110270221 | Nanopatterned Medical Device with Enhanced Cellular Interaction - Disclosed are nanotopography-based methods and devices for interacting with a component of the dermal connective tissue. Devices include structures fabricated on a surface to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. Microneedles may be beneficially utilized for delivery of an agent to a cell or tissue. Devices may be utilized to directly or indirectly alter cell behavior through the interaction of a fabricated nanotopography with the plasma membrane of a cell and/or with an extracellular matrix component. | 11-03-2011 |
20110270222 | Injection Pen For Intradermal Medication Injection - A pen body assembly ( | 11-03-2011 |
20110270223 | Reconstituting Infusion Device - A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed. | 11-03-2011 |
20110276026 | EXTENDED FINGER FLANGE FOR SYRINGE SYSTEMS - The present disclosure describes an extended finger flange that facilitate use of syringe systems. The extended finger flange increases the surface area available for an end user's fingers thereby allowing a more secure grip on the device and providing greater control during administrations of the medication. | 11-10-2011 |
20110276027 | APPLICATORS FOR MICRONEEDLES - An applicator for a microprojection array is described. In one embodiment, the applicator comprises an energy-storing element. Application of force causes the compressed energy-storing element to extend or transition from first and second configurations, releasing stored energy to deploy a holding member in the application which is configured to hold an array of microprojections. In another embodiment, the applicator comprises an energy storing element with two stable configurations, a first stable configuration and second stable configuration. Application of force causes the energy-storing element to transition from the higher energy first stable configuration to the lower energy second stable configuration, releasing the difference in energies of the two states to deploy a holding member in the application which is configured to hold an array of microprojections. | 11-10-2011 |
20110276028 | METHOD AND DEVICE FOR TRANSDERMAL DELIVERY OF PARATHYROID HORMONE USING A MICROPROJECTION ARRAY - A method and a drug delivery system for transdermally administering parathyroid hormone (PTH) in a pulsatile fashion are provided, where the drug delivery system comprises an array of microprojections each comprising PTH. | 11-10-2011 |
20110276029 | NEEDLE BASED HELICAL COIL SAFETY DEVICE - The present disclosure describes anti-needle stick safety mechanism that is passively activated during the normal course of giving an injection. In one embodiment, the device includes a spring member coupled at a proximal end to a needle member and at a distal end to a needle cover. The passive activation of the device is triggered when the needle is inserted to a minimum depth into the patient's tissue to unleash the force of a compressed spring to urge a needle cover towards the distal end of the needle. As the needle is withdrawn from the tissue, the needle cover advances to the end of the needle and as it partially clears the end of the needle, it adopts an orientation that prevents the needle tip from re-emerging from the needle cover. | 11-10-2011 |
20110282322 | Hemodialysis Access Needle Assembly System and Method - An access needle assembly for use with implanted hemodialysis access ports is disclosed. In some embodiments, the assembly includes the following: a tubular needle having an internal cavity including an open leading end having a beveled edge and an open trailing end opposite the leading end, the cavity including a side outflow opening adjacent the trailing end; an obturator configured to be removably positioned within the tubular needle; an interface portion including a central cavity so that the interface portion is positioned adjacent the opening, the interface including a flanged portion extending substantially perpendicular from the central cavity and positioned concentrically over the opening; a conduit portion fluidly connected with the cavity via the flanged portion; and a depth block joined with the interface portion below the flanged portion, the depth block including a lower end opposite the interface portion. | 11-17-2011 |
20110282323 | INFILTRATION CANNULA - An infiltration cannula and method of using the infiltration cannula during a tumescent infiltration procedure are disclosed herein. The infiltration cannula may have an outwardly flaring hub which may be wedged into an adit of a patient to minimize leakage of fluid being infiltrated into the patient. Also, the infiltration cannula may be utilized to hydrate a dehydrated patient by a medically untrained person. The infiltration cannula may also be used to deliver an antibiotic/vasoconstrictive drug solution to minimize surgical site infections. | 11-17-2011 |
20110288525 | OCULAR SURGICAL PROCEDURE - Aspects of forming a wound-conforming pressure seal in the eye, such as upon completion of an ocular surgical procedure, are described herein. Forming the seal includes introducing a plug member into an opening formed in the eye to block vitreous from exiting from the eye through the opening. Consequently, the seal is operable to substantially reduce or eliminate hypotony (i.e., lowering of intraocular pressure below safe levels) and/or endophthalmitis (i.e., infections to the eye). | 11-24-2011 |
20110288526 | Pen Needle Assembly For Intradermal Injection - A pen needle assembly ( | 11-24-2011 |
20110288527 | DEVICE AND METHOD FOR DRUG DELIVERY - A therapeutic treatment device, system and method for improving administration of a temperature sensitive drug into a tissue on the body of a patient at a drug injection site are disclosed. The device includes a treatment element with a controllable heating element in temperature communicative contact with the tissue adjacent to the drug injection site. The controllable heating element is configured to heat the tissue adjacent to the drug injection site to a controllable temperature but does not heat the injected drug above a predetermined limiting temperature, above which degradation of the injected drug may occur. | 11-24-2011 |
20110288528 | EXTRACTABLE FILLER FOR INSERTING MEDICINE INTO VERTEBRAL BODY - An extractable device is used to insert a medicinal filling into a vertebral body. The device comprises a filling member and a pasty medicine. The filling member is made of a flexible and permeable wall and is provided with a holding portion and an injection port via which the pasty medicine is injected into the holding portion after the filling member is inserted into the vertebral body. The holding portion is provided with an opening which is releasably lashed by one end of one or more threads so as to make the opening leakproof. Upon completion of solidification of the pasty medicine in the holding portion of the filling member, other end of the thread is pulled to unlash the opening of the holding portion, thereby enabling the filling member to be extracted from the vertebral body so as to leave only the medicine in the vertebral body. | 11-24-2011 |
20110295229 | In-plane electromagnetic mems pump - A micromechanical pumping system is formed on a substrate surface. The pumping system uses a pumping element which pumps a fluid through valves which move in a plane substantially parallel to the substrate surface. An electromagnetic actuating mechanism may also be fabricated on the surface of the substrate. Magnetic flux produced by a coil around a permeable core may be coupled to a permeable member affixed to a pumping element. The permeable member and pumping element may be configured to move in a plane parallel to the substrate. The electromagnetic actuating mechanism gives the pumping system a large throw and substantial force, such that the fluid pumped by the pumping system may be pumped through a transdermal cannula to deliver a therapeutic substance to the tissue underlying the skin of a patient. | 12-01-2011 |
20110295230 | FLUID TRANSFER DEVICE AND AN ACTIVE SUBSTANCE CARTRIDGE FOR THE FLUID TRANSFER DEVICE, AND A METHOD FOR CONTROLLING THE PRESSURE AT WHICH AN ACTIVE SUBSTANCE IS DELIVERED TO A SUBJECT FROM A FLUID TRANSFER DEVICE - A micro-needle device comprising an active substance layer ( | 12-01-2011 |
20110295231 | EXTRACTABLE FILLER FOR INSERTING MEDICINE INTO ANIMAL TISSUE - An extractable device is used to insert a medicinal filling into an animal tissue. The device comprises a filling member and a pasty medicine. The filling member is made of a flexible and permeable wall and is provided with a holding portion and an injection port via which the pasty medicine is injected into the holding portion after the filling member is inserted into the animal tissue. The holding portion is provided with an opening which is releasably lashed by one end of one or more threads so as to make the opening leakproof. Upon completion of solidification of the pasty medicine in the holding portion of the filling member, other end of the thread is pulled to unlash the opening of the holding portion, thereby enabling the filling member to be extracted from the animal tissue so as to leave only the medicine in the animal tissue. | 12-01-2011 |
20110295232 | Device and Method for the Automatic Initiation of an Injection - A system and method to automatically initiate an injection procedure of a medicament into a patient. In the system, a delivery assembly includes an injector for infusing the medicament into the patient. Further, the system includes a monitor for detecting a parameter characteristic of the procedure, for instance, a pressure indicative of a partial vacuum between the injector and the injection site, a pressure exerted by the patient against the delivery assembly, a conductance, a capacitance, or an optical blood reading. Also, the system includes a timer for determining compliance of the parameter within a predetermined range during a first time interval. In response to the timer, an actuator initiates the injection procedure at the expiration of the first time interval. Further, the actuator may stop the injection procedure if the parameter is outside the predetermined range during a second time interval. | 12-01-2011 |
20110301570 | KIT FOR INJECTING LIQUID INTO A PATIENT AND ASSOCIATED PREPARATION METHOD - This kit includes an injection device comprising a needle having a free end pricked into a septum of an implantable chamber and an intermediate tubing connected downstream to the needle. The kit includes an upstream conduit having an upstream end connected to a liquid dispensing apparatus and a downstream end removably connected to the intermediate tubing. The pressure loss through the upstream conduit is greater than 25% of the total pressure loss taken between the upstream end of the upstream conduit and the free end of the needle, upon injecting liquid through the upstream conduit and the injection device. | 12-08-2011 |
20110306946 | CELL COMPOSITIONS AND USES THEREOF - The present invention relates to blood serum and dermally-derived cells for use in tissue repair. Particularly it relates to blood serum and collagen producing cells for use in the treatment of connective tissue injuries. Preferably the cells and the blood serum are autologous and the connective tissue to be repaired is a tendon or ligament. Also provided is a method of treating connective tissue injuries by the administration of blood serum and collagen producing cells directly to the site of injury. It also relates to the use of blood serum and muscle-like cells for use in the treatment of muscle injury, particularly skeletal muscle injury. | 12-15-2011 |
20110306947 | MEDICATION DELIVERY DEVICE AND METHOD FOR OPERATING A MEDICATION DELIVERY DEVICE - A medication delivery device comprises a housing having a proximal end (P) and a distal end (D), a cartridge for holding a medication (M), the cartridge having an outlet, a moveable piston being retained within the cartridge, a drive member moveable in a proximal direction with respect to the housing for setting a dose of medication (M) to be delivered and in the distal direction with respect to the housing for delivering the dose and a piston rod adapted to drive the piston in a distal direction with respect to the cartridge for delivering the dose. The drive member is releasably coupled to the piston rod. The medication delivery device further comprises a resilient member which is arranged to move the drive member in the proximal direction with respect to the housing after dose delivery, thereby reducing pressure of the piston rod on the piston. | 12-15-2011 |
20110313396 | Adjustable dose setting plunger for syringe - A syringe includes a body for receiving a medicament and a plunger movably connected to the syringe body. The plunger is moved with respect to the syringe body to draw in and dispense the medicament. A plurality of dose setting indicators are disposed on the plunger. The plunger is rotated outwardly from the syringe body to draw medicament into the syringe body. The plunger can be pushed or rotated into the syringe body to dispense the medicament. | 12-22-2011 |
20110313397 | Adjustable plunger dose stop - A syringe includes a body for receiving a liquid medicament and a collar rotatably disposed in or on the body. The collar is rotatable to set a desired dose. A plunger is movably disposed in the collar. The plunger is movable to draw in and dispense the liquid medicament. An end of the collar limits movement of the plunger such that an accurate dose is drawn. | 12-22-2011 |
20110313398 | AUTOMATIC INJECTION DEVICES - An injection device comprises a syringe extendible against a spring bias from a retracted position in a housing to a projecting injecting position. A spring biased plunger has collapsible elbows which, when the plunger is released, initially engage the end of the syringe to drive it to the projecting position, whereupon arresting of the syringe movement causes the elbows to collapse inside the syringe to allow the plunger to engage and drive the bung. | 12-22-2011 |
20110313399 | INTRAVENOUS CANNULA - An intravenous (IV) cannula comprising an elongated body including a distal section for insertion into a blood vessel; at least one channel extending along at least a portion of a longitudinal axis of said cannula section, the at least one channel configured to maintain an amount of at least 10% of a blood flow in the blood vessel; and a central lumen configured to allow an IV fluid flow into the blood vessel. | 12-22-2011 |
20110319864 | INJECTOR FOR AUTO-INJECTION OF MEDICATION AND ASSOCIATED METHOD OF USE - A key-shaped portable injector for delivering a dose of medication, the injector preferably including a cap, a body having an internal cavity, a syringe or cartridge with an attached needle within the internal cavity, a protective sleeve, an activation mechanism and a safety mechanism wherein the injector is reconfigurable from a first, non-deployed configuration where the activation mechanism, syringe or cartridge and a safety mechanism are all in a first position with respect to the body to a second, deployed configuration where the safety mechanism, activation mechanism, and syringe or cartridge are all in a second position with respect to the body and to a third, depleted configuration where the activation mechanism is back to its first position and a protective sleeve is in its second position. | 12-29-2011 |
20110319865 | MICRONEEDLE ROLLER (MNR) INFUSION SYSTEM - A micro-needle roller (MNR) infusion system for transdermal delivery of active agents, skin-care products, and other topical formulations is described herein. The infusion system of the instant invention comprises a needle roller assembly with 0.25 mm needles enclosed in a housing with a vacuum line and a disposable cartridge having the active agent, the skin-care product or the topical formulation. The vacuum delivers the fluid and ensures that the skin is being pulled against the needle wheel surface to ensure that penetration of the needles is complete into the skin, simultaneously the fluid is flowing to the wheel and to skin as it rolls along with the outer housing of the tip cap assembly being occluded to the skin surface. | 12-29-2011 |
20120004638 | DRUG DELIVERY DEVICE WITH NEEDLES AND ROLLER - A delivery device including a roller rotatably mounted on an axle, a reservoir, and at least one hollow needle positioned in the roller are in fluid communication with the reservoir, wherein as the roller rotates about the axle, contents of the reservoir pass through the at least one hollow needle. | 01-05-2012 |
20120004639 | MULTI-STROKE DELIVERY PUMPING MECHANISM FOR A DRUG DELIVERY DEVICE FOR HIGH PRESSURE INJECTIONS - A dual-chambered drug delivery device ( | 01-05-2012 |
20120004640 | OPEN AND CLOSED VALVE MEDICATION DELIVERY SYSTEM FOR HIGH PRESSURE INJECTIONS - A dual-chambered drug delivery device ( | 01-05-2012 |
20120004641 | DUAL-CHAMBERED DRUG DELIVERY DEVICE FOR HIGH PRESSURE INJECTIONS - A dual-chambered drug delivery device ( | 01-05-2012 |
20120010593 | Method and apparatus for a strategic nerve antidote pouch - A strategic nerve antidote pouch includes a backing, a loop panel secured to the backing, first and second straps secured to the backing, and an injector pouch member secured to the backing. The injector pouch member includes first, second, and third injector pouches that receive single nerve antidote injectors therein thereby providing the maximum allowable number of single nerve antidote injectors. The first, second, and third injector pouches provide a visual indication of the number of single nerve antidote injectors employed once a single nerve antidote injectors has been removed, injected, and discarded. The loop panel aids in preventing an accidental injection by a single nerve antidote injector, while the first and second straps along with the loop panel facilitate securing of the strategic nerve antidote pouch with a wearer's body. The strategic nerve antidote pouch further includes a protection edge mounted over a lower portion of the first, second, and third injector pouches to aid in preventing an accidental injection by a single nerve antidote injector. | 01-12-2012 |
20120010594 | Drug Delivery Device - A drug delivery device includes a housing having an interior space, a needle having retracted and deployed states, an injector to move the needle between retracted and deployed states, and a reservoir disposed within the interior space, the reservoir configured to receive a volume of a drug and to be in fluid communication with the needle. The drug delivery device also includes a controller coupled to the injector and the reservoir, and configured to actuate the injector to move the needle from the retracted state to the deployed state only once, and to actuate the reservoir to deliver the volume of the drug to the patient as a single bolus after a preselected time period has elapsed, the controller disposed within the interior space and configured prior to being disposed within the interior space. The delivery device is wearable, disposable, and single-use. | 01-12-2012 |
20120010595 | IMMOBILIZING OBJECTS IN THE BODY - Stabilizing an object in the body of a patient involves the injection of a lower critical solution temperature (LCST) material or other flowable material into the body of the patient so that the material contacts the object. The LCST material or other flowable material then forms a gel in the body such that the object is contained at least partially within the gel and thereby stabilized by the gel such that the object can then be easily fragmented within the body and/or retrieved from the body. | 01-12-2012 |
20120016337 | Collection canister apparatus for closed loop fat harvesting system and method of use thereof - An improved collection canister and method of its use for a closed loop fat harvesting system is disclosed. The collection canister comprising of a main body with inner cavity, handles on each sides, a detachable lid that includes at least two liposuction lure ports, a vacuum port to provide suction within the main body and an additional port for adding additive via a syringe as needed to treat the fat cells such as growth factors. Furthermore, the collection canister has an open/close valve for draining and withdrawing fat cells into syringes. | 01-19-2012 |
20120016338 | CHEMOABLATION OF TISSUE USING BIODEGRADABLE, SOLID SALT DOSAGE FORMS - Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w salt; and (b) inserting one or more of such solid salt dosage forms into the tissue. The solid salt dosage form is optionally inserted into the tissue under real-time ultrasonic observation. An advantage of the present invention is its ability to eliminate toxic byproducts. For example, where NaCl-based solid salt dosage forms are used to effect localized chemical ablation, the concentration is ultimately reduced to the level of normal saline (i.e., about 0.9%) upon absorption by the body of the subject being treated. | 01-19-2012 |
20120022498 | Retractable Safety Syringe with Non-Loaded Seal - A retractable safety syringe may have a needle, needle holder, syringe body, a shaft seal, and a plunger assembly. A proximal portion of the body and a piston of the plunger may define a vacuum chamber. The plunger assembly may comprise a shaft coupled to a piston. The shaft may have at least one non-engaging portion and at least one engaging portion. The plunger assembly is movable between a storage position and working positions. In the storage position, little or no force is exerted on the shaft seal by the non-engaging portion. In the working positions, the engaging portion is in sealing engagement with the shaft seal to seal the vacuum chamber. Stopper movement of the retractable safety syringe may be reduced or eliminated if the retractable safety syringe is prefilled. | 01-26-2012 |
20120022499 | WEARABLE AUTOMATIC INJECTION DEVICE FOR CONTROLLED DELIVERY OF THERAPEUTIC AGENTS - Exemplary embodiments provide wearable automatic injection devices for subcutaneously injecting a therapeutic agent into a patient's body at controlled rates, for example, in a single bolus. Exemplary embodiments provide methods for assembling wearable automatic injection devices for subcutaneously injecting a therapeutic agent into a patient's body at controlled rates. Exemplary embodiments provide methods for using wearable automatic injection devices for subcutaneously injecting a therapeutic agent into a patient's body at controlled rates. | 01-26-2012 |
20120022500 | Compositions and Methods for Induced Brown Fat Differentiation - The invention provides methods and compositions for inducing brown fat cell differentiation through modulation of both Prdm1β and C/EBPβ activity and/or expression. Also provided are methods for preventing or treating obesity or an obesity related disorder in a subject through stimulation of both Prdm1β and C/EBPβ expression and/or activity. Further provided are methods for identifying compounds that are capable of modulating both Prdm1β and C/EBPβ expression and/or activity. | 01-26-2012 |
20120029469 | Lubricated pen needle - A pen needle ( | 02-02-2012 |
20120029470 | POSTERIOR SEGMENT DRUG DELIVERY - A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side. | 02-02-2012 |
20120035584 | Method and Apparatus for Delivering a Lead to a Heart - A method and apparatus for creating and accessing an anatomic space between a heart and a pericardial sac. The apparatus includes a catheter having a cryoadhesion member situated on the distal tip of the catheter. The cryoadhesion member is utilized to adhere to the pericardial sac and to retract the sac to create a tent like structure. The catheter allows introduction of an instrument to access the pericardial sac by puncture. The access to the pericardial sac allows delivery of a device, a drug, a biologic or other substance to the heart or the space around the heart. | 02-09-2012 |
20120041416 | DRUG DELIVERY DEVICE FOR FLUID RESTRICTED PATIENTS - A syringe assembly for connecting to an intravenous (“IV”) line includes: a syringe barrel having an actuation end and a discharge end; a syringe plunger moveable within the syringe barrel, the syringe plunger including a plunger head connected to a plunger arm; a seal between the plunger arm and the syringe barrel, the seal residing on an actuation end side of the syringe plunger; and a tube in fluid communication with the syringe barrel at a location between the seal and the plunger head, the tube having a distal end configured to be connected to the IV line. | 02-16-2012 |
20120041417 | User-Actuated Storage Assembly For Injection Device - A storage assembly is removably connectable to a drug delivery device. A first chamber is disposed in the housing. A plurality of penetrating members are stored in the first chamber. A second chamber is disposed in the housing for storing the plurality of penetrating members after being used in an injection. A transfer drum disposed in the housing transfers one of the penetrating members from the first chamber to an injection position and from the injection position to the second chamber following an injection. | 02-16-2012 |
20120046643 | INJECTION DEVICE - An injection device ( | 02-23-2012 |
20120059354 | METHODS OF IMPROVING FLUID DELIVERY - A method of reducing cell damage can include inserting device into a blood vessel, wherein the device includes a hollow shaft, a lumen, a fluid directing portion comprising a U-shaped lateral orifice extending between the exterior and interior surfaces and a corresponding U-shaped diverter adjacent to the U-shaped lateral orifice, wherein the diverter is disposed within the lumen and transverse to the central axis, and decreasing free plasma hemoglobin levels, thereby reducing damage to circulating blood cells or endothelium during dialysis. | 03-08-2012 |
20120065618 | Delivery system for injection through zone of body - A dispensing device which disperses medicate through a needle across a zone within a body with zero pressure differential. The device includes a needle which is, during use, becomes encapsulated within a tubular needle-receiving member, a therapeutic agent reservoir in fluid communication with the needle, positioned within said housing, and in communication with the needle, a second reservoir, a reservoir-connecting conduit in communication with the therapeutic agent reservoir, a fluid drive in communication with the fluid in the second reservoir and in communication with said reservoir-connecting conduit, and a linear drive attached to said needle or to said needle-receiving member. | 03-15-2012 |
20120078222 | INFUSION PUMPS - Ambulatory infusion pumps, pump assemblies, cartridges, baseplates, cannulas, insertion tools, and related components as well as combinations thereof and related methods. | 03-29-2012 |
20120078223 | WARMING GARMENT AND METHOD FOR PROMOTING VASODILATION - A warming garment and method of making and using are provided. The warming garment may have an inner lining and an outer lining which may form an annular space in which an exothermic composition that is activated upon exposure to oxygen may be disposed. When worn, the warming garment may aid in inducing vasodilation upon a subject's limb through the emanation of heat from the exothermic composition. Once vasodilation is achieved, venipuncture or catheter insertion procedures may be properly initiated. | 03-29-2012 |
20120078224 | DEVICE AND METHOD FOR INTRAOCULAR DRUG DELIVERY - Devices for delivering pharmaceutical formulations into the eye are described. The devices may be integrated to include features that allow safe and atraumatic manipulation of the devices with one hand. For example, accurate placement, including proper angulation, of the device on the eye and injection of a pharmaceutical formulation into the eye can be performed using one hand. The devices may also include improved safety features. For example, the devices may include an actuation mechanism that controls the rate and depth of injection into the eye. Some devices include a dynamic resistance component capable of adjusting the amount of pressure applied to the eye surface. Related methods and systems comprising the devices are also described. | 03-29-2012 |
20120078225 | Dual Chamber Syringe With Retractable Needle - Embodiments of a retractable syringe assembly are provided that include a dual syringe barrel configuration. One or more embodiments include reuse prevention features and features that prevent premature activation of the retraction mechanism. Methods for aspirating and expelling liquid from medical devices are also provided. | 03-29-2012 |
20120078226 | INJECTION CATHETER FOR DELIVERING A THERAPEUTIC AGENT INTO A SUBSTRATE - The invention relates to an injection catheter for delivering a therapeutic agent into a substrate, comprising one or more lumens and a curved delivery element, said lumen serving as a guide for said curved delivery element outside of the substrate; said curved delivery element comprising openings on its distal tip, said distal tip comprising a distal zone and a proximal zone, said injection catheter being characterized in that the specific surface in said distal zone of said distal tip of said curved delivery element is higher than the specific surface in said proximal zone of said distal tip of said curved delivery element. The invention also relates to a process for delivering a therapeutic agent into a substrate. | 03-29-2012 |
20120083762 | METHOD OF DELIVERING MATERIAL OR STIMULUS TO A BIOLOGICAL SUBJECT - A device for delivery of material or stimulus to targets within a body to produce a desired response, the targets being at least one of cells of interest, cell organelles of interest and cell nuclei of interest. The device includes a number of projections for penetrating a body surface, with the number of projections being selected to produce a desired response, and the number being at least 500. A spacing between projections is also at least partially determined based on an arrangement of the targets within the body. | 04-05-2012 |
20120089116 | DEVICES FOR DELIVERING SUBSTANCES THROUGH AN EXTRA-ANATOMIC OPENING CREATED IN AN AIRWAY - Devices and methods for delivering substances to lung tissue through an extra-anatomic passage created in an airway. | 04-12-2012 |
20120089117 | APPARATUS THAT INCLUDES NANO-SIZED PROJECTIONS AND A METHOD FOR MANUFACTURE THEREOF - An apparatus that includes a nano-projection array and an application unit configured to displace the nano-projection array to thereby deliver a composition (e.g., vaccine) to a controlled depth within the skin. The nano-projection array includes nano-projections carried by a carrier substrate. The application unit includes a peripheral structure and a displaceable carrier. The nano-projection array can be disposed within the peripheral structure. Displacement of the displaceable carrier causes a corresponding displacement to the nano-projection array. The displacement of the displaceable carrier can be controlled. For instance the distance of displacement of the displaceable carrier can be controlled. A method or process for manufacturing the apparatus is also provided. | 04-12-2012 |
20120089118 | DELIVERY OF BISPHOSPHONATES BY MICROINJECTION SYSTEMS - A system for the administration of a bisphosphonate to a subject comprises a bisphosphonate formulation and a microinjection device. In an embodiment, the bisphosphonate formulation includes ibandronate sodium. In some cases, the bisphosphonate formulation includes an excipient. The bisphosphonate formulation may be delivered to the subject subcutaneously, transdermally or intradermally. | 04-12-2012 |
20120089119 | SYSTEM AND METHOD FOR AN INJECTION USING A SYRINGE NEEDLE - An auto-injector for injecting a fluid medicament into a patient from a pre-filled syringe requires a disposable cassette that is selectively engageable with the reusable injector. The syringe is latched onto the cassette, and the cassette is then engaged with the injector. Activation of the injector causes a first motor to move the syringe so its needle is extended from a concealed position inside the cassette for injection of the medicament. A second motor on the injector is then activated to expel fluid medicament from the syringe. Then, the first motor is again activated to withdraw the syringe into the cassette for disposal of the cassette/syringe after an injection. | 04-12-2012 |
20120095438 | MEDICATION DELIVERY DEVICE WITH FOLDABLE FINGER PAD - A medication delivery device is configured to deliver medication when a button element is moved, the medication delivery device having a folding finger pad. | 04-19-2012 |
20120095439 | IMPLANTABLE THERAPEUTIC DEVICE - A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. The length of the channels extending from the first side to the second side may comprise an effective length greater than a distance across the porous structure from the first side to the second side. The therapeutic device may comprise a penetrable barrier to inject therapeutic agent into the device when implanted in the patient. | 04-19-2012 |
20120095440 | INJECTION PORT SYSTEM FOR INTRA-MARROW INJECTION/INFUSION - An injection port system for placement in or on an individual includes a first port ( | 04-19-2012 |
20120095441 | STEM CELL DELIVERY DEVICE FOR ORTHOBIOLOGICS APPLICATIONS - A method and apparatus for thawing and delivery of cryogenically frozen biological material, such as stem cells includes a housing for receiving a pouch of frozen cells, a heating element against which the pouch is placed for applying defrosting heat to the pouch, and a squeezing apparatus for applying a squeezing force to the pouch after or upon thawing of the cells. The squeezing force may be applied by a roller pressing the pouch against the heating element, which forces the thawed cells from a needle or tube connected to the housing and/or to the pouch. A rechargeable battery in the housing supplies power to the heating element and the squeezing apparatus. | 04-19-2012 |
20120101475 | High Efficiency Auto-Injector - An auto-injector apparatus and associated methods utilizing specific dimensions and parameters of use for the auto-injector are provided for achieving increased effectiveness of the auto-injector device in delivering medicament into the patient's body, and in dispersion of the medicament from the initial injection site into the surrounding bodily tissues. | 04-26-2012 |
20120109102 | CANNULATED SYRINGE - A set of instruments configured to deliver a therapy to a bone can include a cannulated syringe. The cannulated syringe can extend along a longitudinal axis between a proximal and a distal end. The cannulated syringe can have an inner tube and an outer tube that are interconnected at the distal end as a single fixed unit. A first cannulation can be formed along the longitudinal axis of the cannulated syringe within the inner tube and a second cannulation can be formed within an annular space between the inner and outer tubes. The outer tube can define an opening through a sidewall thereof. The cannulated syringe can be closed from fluid communication between the inner and outer tubes. | 05-03-2012 |
20120109103 | DEVICES AND METHODS FOR CONTROLLED-DEPTH INJECTION - Devices and methods for simultaneous injection or delivery of two or more substances from separate syringes. The syringes are loaded into a device that has a handle and a screw driven mechanism for simultaneously depressing the plungers of the syringes. The user grasps the handle and positions the device. Thereafter, the screw mechanism is used to simultaneously advance the plungers of the syringes thereby simultaneously expelling the substances from the syringes. | 05-03-2012 |
20120109104 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 05-03-2012 |
20120116348 | LIQUID MEDICINE INJECTION AMOUNT ADJUSTING METHOD, LIQUID MEDICINE INJECTION AMOUNT ADJUSTING APPARATUS, AND LIQUID MEDICINE INJECTING SYSTEM - In a liquid medicine injecting system, an open route is formed in which a liquid medicine flows from a container that contains the liquid medicine to a blood vessel of a biological body via a micro-pump, a flow volume sensor, and a tube. A back pressure from the biological body directly operates against the micro-pump via the open route. When the flow volume of the liquid medicine is constant, power of the micro-pump has a constant relationship with the back pressure. The flow volume of the liquid medicine is adjusted to be a target volume by controlling the power of the micro-pump, and the power of the micro-motor is monitored. An abnormal injecting state of the liquid medicine caused by such as pulling out of an injection needle from the biological body is immediately detected with high accuracy based on the monitored result of the power of the micro-pump. | 05-10-2012 |
20120116349 | Medicated Module with Premix Medicament - A medicated module ( | 05-10-2012 |
20120123385 | DEVICES, SYSTEMS, AND METHODS FOR MEDICAMENT DELIVERY - An apparatus includes a housing, a medicament container, an actuator, and a biasing member. The actuator is configured to move the medicament container within the housing when the actuator is moved from a first configuration to a second configuration. The actuator includes a gas container and a puncturer. When the actuator is in the first configuration, a portion of the puncturer is disposed apart from the gas container. When the actuator is in the second configuration, the portion of the puncturer is disposed within the gas container. The gas container has a longitudinal axis offset from a longitudinal axis of the medicament container. The biasing member is configured to bias the actuator toward the second configuration. | 05-17-2012 |
20120123386 | INTRADERMAL INJECTION ADAPTER - An intradermal injection assembly for injecting a medicament into skin could form an intradermal needle with an adapter, an intradermal syringe with an adapter or an adapter for a merger with a syringe with a cannula. The intradermal adapter in these devices has a body having a longitudinal axis, a central portion having a cannula channel and a distal protrusion extending generally parallel to the longitudinal axis. The distal protrusion of the adapter has a first skin contacting surface extending generally parallel to the longitudinal axis. At least a portion of the distal protrusion is generally transparent such that the portion of the cannula that extends distally relative to a demarcation plane can be viewed through the distal protrusion during insertion of the cannula into a patient's skin. | 05-17-2012 |
20120123387 | HOLLOW MICRONEEDLE ARRAYS - The present disclosure relates to apparatus, assemblies, combinations, and methods for infusing fluids by hollow microneedles. | 05-17-2012 |
20120130340 | Tissue Desensitization Instrument & Method - An automatic fluid injector ( | 05-24-2012 |
20120130341 | COMBINED IV BAG AND PUMP SYSTEM AND METHOD - An intravenous fluid container is disclosed, wherein the fluid container comprises a bag, a fluid reservoir formed within the bag, an outlet, and a pumping element formed within the bag and fluidically coupled between the fluid reservoir and the outlet. | 05-24-2012 |
20120130342 | AUTOINJECTOR HAVING AN OUTER PACKAGING AND A NEEDLE SHEATH REMOVING MEANS - An autoinjector device for delivering a dose of medicament including a syringe including a needle wherein, prior to use of the device, the needle is substantially covered by a needle sheath ( | 05-24-2012 |
20120130343 | Tissue penetration device - An agent injection device is provided that is capable of injecting an agent to a known predetermined tissue depth. An injection member has an elongate injection shaft with an outlet port configured to dispense an agent at a controllable time. A controllable driver is coupled to the elongate injection shaft and is configured to drive the injection member into target tissue. A velocity control system is in communication with the controllable driver and is configured to control the velocity of the elongate injection shaft. | 05-24-2012 |
20120130344 | Skin Gripping Means, Injector Including the Skin Gripping Means and Method of Performing a Subcutaneous Injection - A skin gripping means for use with an injector ( | 05-24-2012 |
20120130345 | RENAL NERVE STIMULATION METHOD FOR TREATMENT OF PATIENTS - A method and apparatus for treatment of heart failure, hypertension and renal failure by stimulating the renal nerve. The goal of therapy is to reduce sympathetic activity of the renal nerve. Therapy is accomplished by at least partially blocking the nerve with drug infusion or electrostimulation. Apparatus can be permanently implanted or catheter based. | 05-24-2012 |
20120130346 | Medicated Module for a Drug Delivery Device - A medicated module ( | 05-24-2012 |
20120136337 | HYPODERMIC NEEDLE SYSTEM AND METHOD OF USE TO REDUCE INFECTION - A hypodermic needle system and method for reducing the incidence of infections due to administering fluids by injection to humans or animals is provided. The hypodermic needle system may include a needle with an insert disposed within its hollow channel to substantially prevent bacteria, fungi and/or other organisms/contaminants, which may be present on the exterior surface to be penetrated, from adhering to the inner surfaces of the needle's channel or become trapped in the needle bore. The hypodermic needle system may include a film that covers at least one surface of the needle or insert, and/or have a bent or curved tip to reduce the ability of infectious agents to adhere to said surface/space within the needle. Additionally, the hypodermic needle system may include an anti-infection agent, such as an antibiotic or antiseptic to further reduce the incidence of infections, and may include an attachment member which reduces the risk of infection. | 05-31-2012 |
20120150145 | METHODS OF TISSUE SAMPLING, COLLECTION, PROCESSING AND RE-INJECTION USING MODULAR, DISPOSABLE TISSUE ASPIRATION, PROCESSING, COLLECTION AND/OR RE-INJECTION COMPONENTS - Methods of tissue sampling, collection, in situ processing and re-injection using modular, disposable tissue aspiration, processing, collection and/or re-injection components. | 06-14-2012 |
20120150146 | Syringe Devices, Components of Syringe Devices, and Methods of Forming Components and Syringe Devices - A syringe device includes a syringe barrel and piston having a fluid passageway extending from a vial port. Another syringe device includes a syringe barrel, a piston sleeve and an insert. A channel extends along a side of the insert. A valve controls fluid communication between the channel and the syringe barrel. Another syringe device has a syringe barrel, a piston sleeve and an insert. A valve controls fluid communication between a compartment within the insert and the syringe barrel. A method of preparing a medication includes providing a component within a syringe barrel and another component within a compartment of a piston insert. A seal is over-molded onto a tip of the insert and an end of a piston sleeve. The sleeve is rotated relative to the insert to establish fluid communication between the compartment and the barrel chamber. | 06-14-2012 |
20120157964 | DEVICE AND METHOD FOR THE DELIVERY OF MEDICINAL LIQUID DIRECTLY FROM A SMALL BOTTLE (VIAL) - A device for the delivery of medicinal liquids, in which the device includes a base configured for sealing attachment to a container pre-filled with liquid medicine and a displaceable actuator element associated with the base. The association is that of a piston and a cylinder such that the base and the displaceable actuator element define between them a pressure generating volume. The base includes a piercing element having at least one air delivery passage providing fluid communication between the pressure generating volume and an interior of the container, the piercing element also includes at least one liquid delivery passage providing fluid communication between the interior of the container and a medicinal delivery element. | 06-21-2012 |
20120157965 | HAZARDOUS AGENT INJECTION SYSTEM - Injection systems comprising a powered injector and one or more hazardous agents are disclosed. | 06-21-2012 |
20120157966 | Drive Mechanism for a Drug Delivery Device - A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing ( | 06-21-2012 |
20120157967 | SYSTEM AND METHOD FOR MINIMALLY INVASIVE DISEASE THERAPY - A system for treating a lesion site of a patient is disclosed. The system includes a cannula having a lumen, a conduit in communication with said lumen, an introducer stylet removably disposed within said cannula, a resecting device selectively insertable within said cannula, and an adjuvant treatment device selectively insertable within said cannula. | 06-21-2012 |
20120165783 | DEVICE FOR AT LEAST ONE OF INJECTION OR ASPIRATION - Micro-volume devices, systems, and associated methods that facilitate the injection or aspiration of precisely controlled volumes of materials at precisely controlled rates are provided. In one embodiment, a micro-volume device includes a syringe and a lead screw connected to a plunger of the syringe. A mechanical interface is connected to the lead screw and includes a first set of cams adjacent a proximal portion and a second set of cams adjacent a distal portion. A mechanism is configured to oscillate a structure in a direction parallel to a longitudinal axis of the lead screw such that one or more projections of the structure to alternatively engage cams of the first and second sets of cams in a manner that results in rotation of the mechanical interface in a single direction for highly controlled linear displacement of the plunger. | 06-28-2012 |
20120165784 | AUTOMATIC NEEDLE GUARD - A device for selectively protecting a needle includes an adapter holding the needle and a guard engaging the adapter for relative movement therebetween. Further, the device includes a means for guiding movement between the adapter and the guard. Structurally, the guiding means includes a “V” shaped slot in the guard and a radially-extending boss on the adapter. The boss is received in the slot to limit relative movement between the guard and the adapter. Specifically, in a first position of the device, the boss is in a first leg of the slot and the needle partially extends beyond the guard. In a second position, the boss is held at the apex of the slot and the needle fully extends beyond the guard. In a third position, the boss is in the second leg of the slot and the needle is retracted into the guard to protect the needle. | 06-28-2012 |
20120172834 | TISSUE SAMPLING, PROCESSING AND COLLECTION DEVICE AND METHOD OF USING SAME - Methods of collecting fat tissue samples in tissue collection syringes mounted in an in-line fat sampling device connected to a hand-held power-assisted tissue aspiration instrument. | 07-05-2012 |
20120172835 | Multi-Conduit Balloon Catheter - A suctioning and irrigating sinus balloon catheter is provided for treating a patient's paranasal sinus system, including dilating prepared openings, and natural ostia and ducts and excising sinus cavities and choana. The catheter has a number of fluid carrying conduits to provide irrigation, suction and inflation/deflation to the distally mounted balloon. The catheters have sufficient stiffness and column strength that the balloon carrying distal segment of the catheter can be pushed into the prepared opening, natural ostium or duct, choana or sinus to be excised. Some catheters can be hand bendable by the surgeon. Some catheters provide the capability of threading an endoscope through one of the conduits. The methods use the balloon catheters to dilate prepared openings to selected parts of the sinus system, to dilate natural ostia and ducts of the sinus system, choana, and/or to dilate sinus cavities to remove them. | 07-05-2012 |
20120172836 | IMPLANTABLE DEVICE FOR PRODUCTION OF INTERLEUKIN-1 RECEPTOR ANTAGONIST - Treatments and devices for generating and using interleukin-1 receptor antagonist (IL-1ra). An implantable device is loaded with adipose tissue and/or white blood cells and inserted into an inflammation site in a patient to produce interleukin-1 receptor antagonist in vivo. The implantable device has an enclosed or substantially enclosed body that defines an internal space. At least a portion of the body comprises a first bioresorbable material and a second bioresorbable material is within the internal space along with one or more voids. The second bioresorbable material includes an activation surface to activate adipose tissue and/or white blood cells loaded into the device to produce IL-1ra. | 07-05-2012 |
20120179137 | Compact Device That Rapidly Mixing and Deliverings Substances To a Patient - Injection devices are disclosed for injections of substances. The disclosed devices separately may hold two separate substances, e.g., solid, liquid or gas substances, in separate compartments which are interrupted so that the separate substances come into contact during the activation of the device. One disclosed device includes a needle for injection and two substances that are mixed with only a few actions by the operator of the device. The device may or may not activate mixing by the removal of a sleeve which triggers compartment interaction through movement of pins, pegs, springs, wires, string, or other mechanisms which allow the materials held in separate chambers to come into contact with each other. Operator error during mixing and checking the dosage of substances to be injected is avoided with the disclosed devices. Also, the needle is maintained in a sterile state because the needle is held internally of the device until the sleeve is removed and the device begins to activate. | 07-12-2012 |
20120191064 | METHODS AND APPARATUS FOR SUB-RETINAL CATHETERIZATION - Devices and methods are provided for access to the sub-retinal space that lies between the retina and the choroid in order to introduce therapies to the retina and more specifically to the sensory retina and RPE, particularly in the region of the macula. The devices comprise a catheter that incorporates advantageous size, flexibility and tip features to properly, accurately and atraumatically access the sub-retinal space. Ancillary devices to assist in placing catheters into the sub-retinal space are also provided. The catheter devices incorporate a lumen for delivery of therapeutic substances or devices into the eye. | 07-26-2012 |
20120191065 | INTRADERMAL PEN ADAPTER - An intradermal injection adapter includes a body having a longitudinal axis and a central portion located distally relative to the body along the longitudinal axis. The central portion has a cannula channel therethrough extending generally parallel to the longitudinal axis. A cannula within the cannula channel has a sharpened tip for injection into a patient and a sharpened opposite proximal end for injection into a pen injector. A distal protrusion has a first skin contacting surface extending generally parallel to the longitudinal axis. The first skin contacting surface is spaced from the cannula such that a distal portion of the cannula extends generally parallel to the first skin contacting surface. | 07-26-2012 |
20120191066 | Prefilled Cannula Assembly - A method and system for proving a cannula arrangement ( | 07-26-2012 |
20120191067 | Injection Device with Sealed Luer Fitting - The invention relates to an injection device ( | 07-26-2012 |
20120197232 | METHODS AND DEVICES FOR AUTOFLUSH SYRINGES - Described herein are syringe devices, systems and methods. In general, the syringe may include a first chamber and a cartridge movable within the first chamber. The cartridge may include a cartridge chamber and a valve in fluid communication with the cartridge chamber and the first chamber and having an open configuration and a closed configuration. The valve may allow movement of a liquid out of the cartridge chamber while in a open configuration. The cartridge may also include a second end, movable within the cartridge chamber, and a locking mechanism having a locked configuration and an unlocked configuration, the locking mechanism preventing movement of the second end within the cartridge chamber while in the locked configuration. | 08-02-2012 |
20120197233 | Injection Arrangement - The invention relates to a pump unit ( | 08-02-2012 |
20120203197 | METHOD AND APPARATUS FOR ASPIRATION - An aspiration apparatus is described that includes a guide and a set of needles. The guide preferably has an approximately conical shape with a decreasing diameter in the distal direction. A plurality of lumens extend between a distal end portion and a proximal end portion of the guide. The needles have a tubular wall and are slidingly positionable in the lumens. The needles include a longitudinal section of the tubular wall that has a plurality of apertures that decrease in size in the proximal direction. The apertures define an approximately conically shaped area of harvest. The aspiration apparatus can connect to an external source of reduced pressure through the guide or directly to each needle. | 08-09-2012 |
20120203198 | Nighttime Basal Dosing Device - A basal hub for attaching to an infusion base is disclosed. The hub includes a fluid reservoir and pressure actuating device. A septum portion of the reservoir is configured to be opened by a flow cannula that is in fluid communication with an infusion cannula of the infusion base, when the basal hub is attached to the infusion base. The pressure actuating device applies pressure to the fluid reservoir, such that when the septum portion of the fluid reservoir is pierced by the by the flow cannula, liquid stored in the fluid reservoir is released from the fluid reservoir into the infusion cannula of the infusion base via the flow cannula. The basal hub is configured to deliver a basal dose of insulin during periods of inactivity, such as during sleep time. | 08-09-2012 |
20120203199 | Method and apparatus for providing access to an internal body organ - Catheter systems and methods for facilitating the delivery of a therapeutic agent directly to the interior of a body organ, and/or the extraction of material from said organ. The catheter distal end is placed within the body organ to be treated. The catheter may carry a fixation device near the catheter distal end. When implanted, the fixation device retains the catheter distal end in the organ despite normal patient activity. The fixation device may include porous material to promote soft tissue ingrowth for anchoring the catheter distal end within the organ. | 08-09-2012 |
20120203200 | DEVICE AND METHOD FOR DELIVERING MEDICINE INTO THE TYMPANIC CAVITY - A device for substance delivery to and/or extraction from the tympanic cavity, comprising: a housing, having a distal surface, a proximal surface that is opposite to the distal surface, and a circumscribed surface that connects the distal surface and the proximal surface; at least one piercing element having at least one proximal piercing end and at least one distal piercing end, disposed within the housing in such manner that the at least one distal piercing end is/are generally facing the distal surface of the housing; and a means for flexing the tympanic membrane toward the distal end of the at least one piercing element. | 08-09-2012 |
20120209245 | Process for using a needle having multiple apertures for injections into subcutaneous tissue - The present invention discloses a process for using needle having multiple apertures for insulin injections into subcutaneous tissue, whereby the insulin dispersion pattern is such that insulin is absorbed at an optimal rate even when the needle is inserted too deeply into the muscle layer or when the insulin is injected into lipohypertrophic tissue. | 08-16-2012 |
20120209246 | System and Method for Pain-Free Injections - A system for administering pain-free injections includes an electric current source having at least two electrodes attached adjacent an injection site, the electric current source producing a variable numbness pattern and providing a frame of reference for identifying a plurality of sub-areas of the injection site; and a probe applied to the plurality of sub-areas of the injection site for pain-response testing, wherein one or more areas of numbness in the variable numbness pattern are identifiable according to the plurality of sub-areas of the injection site. A fence may be removably applied to the injection site and provide a frame of reference for identifying a plurality of sub-areas of the injection site, and may aid in identifying one or more areas of numbness in the variable numbness pattern. The fence may be removably applied to the injection site via a belt or manual pressure. | 08-16-2012 |
20120209247 | Safe Disposable Injector with Changeable and Automatically Retractable Needle - A safe disposable injector with a changeable and automatically retractable needle includes a needle cylinder ( | 08-16-2012 |
20120209248 | DEVICES AND METHODS FOR TISSUE TRANSFER - Devices and methods for tissue transfer are described where a cannula may be inserted into the breast of a subject at one of several points of entry. Insertion of the cannula into the breast may be accomplished by using a guidance system to distinguish between tissue types. Once desirably positioned, the cannula may be withdrawn from the breast while automatically (or manually) injecting the fat in multiple deposits of adipose tissue or fat such that the deposited fat remains within the tract formed by the withdrawn cannula. Multiple tracts of the deposited fat may be injected within the breast until the breast has been desirably remodeled and/or augmented. | 08-16-2012 |
20120209249 | Injection Arrangement for a Flowable Drug - The invention refers to an injection arrangement ( | 08-16-2012 |
20120220980 | Transdermal Patch Containing Microneedles - A transdermal patch that can easily deliver a controlled volume of a fluidic drug compound to the skin is provided. More particularly, the patch contains a microneedle assembly that is configured to be placed in fluid communication with a drug delivery assembly. The microneedle assembly contains a support and a plurality of microneedles that extend outwardly from the support. The microneedles are formed with one or more channels of a certain dimension such that passive capillary flow drives the flow of the drug compound. The drug delivery system contains a reservoir for the drug compound that is in fluid communication with a rate control membrane that helps control the flow rate of the drug compound by modulating its pressure downstream from the reservoir. A release member is also positioned adjacent to the microneedle and drug delivery assemblies. Prior to use, the release member acts as a barrier to the flow of the drug compound and thus inhibits premature leakage. In this manner, the patch can initially be provided in an “inactive” configuration in which the drug compound is securely retained. When it is desired to release the drug compound, the patch can simply be activated by at least partially separating the release member from the drug delivery and microneedle assemblies. | 08-30-2012 |
20120220981 | Transcutaneous Multimodal Delivery System (TMDS) - A transcutaneous multimodal delivery device for drug delivery and the methods of making and using the same are provided. | 08-30-2012 |
20120226260 | METHODS AND DEVICES FOR DRUG DELIVERY TO OCULAR TISSUE USING MICRONEEDLE - Methods and devices are provided for targeted administration of a drug to a patient's eye. In one embodiment, the method includes inserting a hollow microneedle into the sclera of the eye at an insertion site and infusing a fluid drug formulation through the inserted microneedle and into the suprachoroidal space of the eye, wherein the infused fluid drug formulation flows within the suprachoroidal space away from the insertion site during the infusion. The fluid drug formulation may flow circumferentially toward the retinochoroidal tissue, macula, and optic nerve in the posterior segment of the eye. | 09-06-2012 |
20120232522 | METHODS AND DEVICES FOR DRUG DELIVERY TO OCULAR TISSUE USING MICRONEEDLE - Methods and devices are provided for targeted administration of a drug to a patient's eye. In one embodiment, the method includes inserting a hollow microneedle into the sclera of the eye at an insertion site and infusing a fluid drug formulation through the inserted microneedle and into the suprachoroidal space of the eye, wherein the infused fluid drug formulation flows within the suprachoroidal space away from the insertion site during the infusion. The fluid drug formulation may flow circumferentially toward the retinochoroidal tissue, macula, and optic nerve in the posterior segment of the eye. | 09-13-2012 |
20120232523 | DEVICES FOR DELIVERING SUBSTANCES THROUGH AN EXTRA-ANATOMIC OPENING CREATED IN AN AIRWAY - Devices and methods for delivering substances to lung tissue through an extra-anatomic passage created in an airway. | 09-13-2012 |
20120239000 | Drug Delivery Method Via Brain Extracellular Space and a Device Thereof - The present invention relates to a method for drug delivery via brain extracellular space (ECS). It includes putting head of patient in an imaging apparatus; generating dynamic images of the brain via the imaging apparatus; delivering drugs into brain ECS of the patient according to the dynamic images and the drugs get to the therapeutic target by simple diffusion along concentration gradient. The present invention also relates to a device for drug delivery via brain ECS. Basing on the self-diffusion delivery (SDD) of drugs in brain ECS, the present invention can deliver drug into the ECS of the brain's relatively safe area in low speed, with small amounts of doses and without extra stress. Therefore, the present invention can reduce delivery time and dose of drugs, relieve injection pressure, decrease damages on normal brain tissue, and reduce the cost of treatment observably. | 09-20-2012 |
20120245557 | Laminar Injection Apparatus and Method - A laminar injection apparatus may include a slider layer, a needle flexibly coupled to the slider layer, a medication reservoir in fluid communication with the needle, and a needle guiding layer comprising an aperture for deflecting the needle from a substantially horizontal orientation to a substantially vertical orientation in response to moving the slider layer relative to the needle guiding layer. One or more spring layers may extend the laminar structure into an extended laminar structure. The needle may be thrust into a subject by compressing the extended laminar structure and causing the needle to protrude from the structure and penetrate a subject. In response to the compressive force on the laminar stack, medication may be forced from the medication reservoir through the needle and into the subject. | 09-27-2012 |
20120245558 | SELF-INJECTION DEVICE - A self-injection device ( | 09-27-2012 |
20120245559 | Grip for self-injectable device - The present invention, in one embodiment, is a gripping apparatus to ergonomically grip a self-injectable device (such as, for example, an insulin pen) to thereby provide a user's fingers with a gripping means on the self-injectable device so that the combination of the apparatus with the self-injectable device facilitates one-handed operation on various parts of the human body and comprises a complete operational self-injectable assembly. The apparatus is adapted to snap-fit the body of a self-injectable device (e.g., an insulin pen) by inserting the self-injectable device longitudinally through the flange apertures of the apparatus, and twisting the apparatus around the device's body until the apparatus is in snug engagement with the device. The apparatus assists the user in using the self-injecting device for injection on any portion of the human body. | 09-27-2012 |
20120253314 | PALM-CONTROLLED INJECTORS - A palm-controlled device is disclosed for injection of a substance into an organism. The device includes a palm-receiving surface for receiving a palm of a hand, the palm receiving surface being shaped so that the palm is substantially parallel to a surface of an injection site of the organism while operating the device. The palm receiving surface can also be shaped so that the palm is substantially perpendicular to a surface of the injection site. The device also includes an injector having at least one pre-filled syringe, the palm-receiving surface being cooperative with the injector such that when pressure is applied to the palm-receiving surface, the injector is actuated so as to inject contents of the at least one pre-filled syringe. Actuation of the injector is by gradual pressure; not sudden motion. Single or multiple doses of same or different medications can be included in a single injector. | 10-04-2012 |
20120253315 | INJECTION NEEDLE FOR FRACTURES - A cannula having proximal and distal ends defines a hollow body. A tissue-piercing tip is formed at the distal end of the cannula and is fluidically sealed from the hollow body. At least one opening is formed in a sidewall of the cannula and fluidically coupled to the hollow body. A fracture may be treated by advancing the tip through soft tissue so that the at least one opening is at least partially disposed within or adjacent to the fracture. The needle is oriented so that the at least one opening faces an exposed end of fracture or within the plane of the fracture line. Then, a therapeutic composition, such as a bone growth factor, is pressured through the hollow body to exit from the at least one opening. | 10-04-2012 |
20120253316 | PERCUTANEOUS BIOLOGIC DELIVERY SYSTEM - A bone grafting delivery device, method and kit is provided. The bone grafting material delivery device may include a needle having a cutting edge located at a distal end of the needle. The needle may be configured to be inserted within a bone via an entry point created through the skin of a patient. Additionally, the bone grafting material delivery device may include a plurality of dilators attachable sequentially to the needle using a swivel assembly. The plurality of dilators may be configured to articulate relative to needle in a plurality of directions via the swivel assembly. Furthermore, a final dilator of the plurality of dilators may include an opening at a distal end of the final dilator for depositing bone grafting material onto the bone or in a void. | 10-04-2012 |
20120253317 | ADIPOSE TISSUE MANAGEMENT SYSTEMS - The utilization of stored fat cells is provided. Fat cells removed from a patient may be subdivided into a number of fat cell subdivisions for utilization in a series of medical procedures. The fat cell subdivisions can be prepared for short term storage for use in medical procedures to be performed within a defined period time or long term storage for use in one or more medical procedures to be performed in the future. Medical practitioners can utilize stored fat cell subdivisions in a series of procedures on a patient. | 10-04-2012 |
20120259311 | FAT REMOVAL DEVICE AND OBESITY TREATMENT - A method for treatment for obesity comprising a medical device attached or implanted in patient's target body organs, wherein in each one of the device attachments, or daily in the case of long continuous attachment, the device removes up to 100 grams of energy containing materials from the body. The medical device optionally contains needles or alternatively contains crawling worm like arm. The energy containing materials may be fat cells, fatty acid molecules driven out from the fat cells or lipids or carbohydrates molecules such as glucose from the blood stream. | 10-11-2012 |
20120259312 | METHODS AND DEVICES FOR BONE PREPARATION - A manifold has at least one manifold aperture extending therethrough and selectively placed in fluid communication with a fluid source. An insertion structure has at least one interior cavity at least partially defined by a structure shell and is selectively placed in fluid communication with a corresponding manifold aperture. The insertion structure is configured for selective placement in a penetrating relationship with a patient tissue below a surface of the patient tissue. At least one shell perforation extends through the structure shell and places the interior cavity in fluid communication with a surrounding ambient space. At least one fluid path extends from the fluid source, through the manifold aperture, into the interior cavity, through at least one shell perforation, and at least one of a proximate relationship and a contacting relationship with the patient tissue beneath the outer surface thereof. A fluid is directed along the fluid path. | 10-11-2012 |
20120259313 | APPARATUS AND METHODS FOR LIMITING PRESSURE AND FLOW WITHIN A MEDICAL INJECTOR - A medical injector ( | 10-11-2012 |
20120265166 | DEVICES AND METHODS FOR ENHANCING DRUG ABSORPTION RATE - Devices, systems and methods directed to a drug delivery device including a soft subcutaneously insertable cannula are disclosed. Some embodiments of the cannula include an elongated soft tube having a plurality of apertures spaced around and/or along a wall of the elongated soft tube. The plurality of apertures is configured for fluid flow therethrough resulting-in/causing an increase in an absorption rate of the fluid in the body of the user. The drug delivery device can be an insulin pump. | 10-18-2012 |
20120265167 | BIOCOMPATIBLE MATERIAL FOR ORTHOPEDIC USES - Biocompatible material for bone repair, especially vertebral bone repair, preferably has three components. The first component is silicon nitride ceramic spheres or shells that can be polyhedral in shape. When grouped together, these ceramic spheres or shells form tessellates having a similar degree of stiffness, strain and stress resistance to cancellous bone. The second component comprises various bioactive factors that are preferably osteoconductive, osteoinductive and osteogenic. The third component is a liquid or gel that combines with the first and second components to form a composite. | 10-18-2012 |
20120271275 | MEDICAL DEVICES AND METHODS COMPRISING AN ANABOLIC AGENT FOR WOUND HEALING - Improved medical devices and methods are provided comprising an anabolic agent for wound healing. These improved medical devices and methods can enhance wound healing in wounds from cuts, abrasions, lesions, burns including sunburn, surgical incisions, pressure ulcers, diabetic ulcers, traumatic wounds, or other injuries or maladies, which can be chronic or non-chronic in origin. In some embodiments, the medical device comprises a drug depot that releases the anabolic agent over at least 3 days to enhance wound healing. | 10-25-2012 |
20120271276 | SAFETY ASSEMBLY FOR A SYRINGE - A safety support device for a syringe comprises a support sheath for the body of the syringe and an inner sheath suitable for sliding relative to the support sheath between a waiting, retracted position and the extended position for protecting the needle of the syringe. The device has means for holding the syringe body relative to the support sheath and retaining means suitable for being activated to retain g the inner sheath in the waiting, retracted position inside the support sheath and for being deactivated by the piston of the syringe to allow the inner sheath to extend into its protective, extended position. | 10-25-2012 |
20120277724 | Disposable Double Point Injection Needle and an Insulin Injection System Comprising a Disposable Double Point Injection Needle - A disposable double pointed injection needle has a needle hub to which a thin needle cannula is permanently fastened and which needle hub can be mounted on to a syringe comprising a dose setting and injection mechanism and a cartridge containing a liquid medicine to be injected subcutaneously into a human body. The needle hub is provided with a safety shield guided on the needle hub. The safety shield is urged in a direction away from the needle hub by a spring located between the needle hub and the safety shield. After injection the shield is moved away from the needle hub by the spring and locked in an irreversible position where the safety shield covers the needle cannula and prevents accidental needle stick injuries. | 11-01-2012 |
20120283695 | TRANSDERMAL DRUG DELIVERY PATCH AND METHOD OF CONTROLLING DRUG RELEASE OF THE SAME BY NEAR-IR - A transdermal drug delivery patch and a method of controlling the drug release of the transdermal drug delivery patch by near-IR are disclosed. The transdermal drug delivery patch comprises a substrate, carriers and drugs. The drugs are encapsulated in the carriers, and the carriers having the drugs are disposed on a surface of the substrate. The carriers are formed of biodegradable polymers, and nano-particles with a photothermal conversion effect are loaded in the carrier. When the carriers are punctured into the skin and the nano-particles in the carrier absorb the near-IR, the near-IR is converted into heat by the nano-particles to melt the carrier and thus releasing the drugs encapsulated in the carrier into the skin. Accordingly, the speed of releasing the drugs encapsulated in the carrier can be controlled accurately by the near-IR. | 11-08-2012 |
20120283696 | Self-Injection Device with Multi-Position Cap - A self-injection device ( | 11-08-2012 |
20120283697 | METHODS FOR STIMULATING A DORSAL ROOT GANGLION - Some embodiments of the present invention provide stimulation systems and components for selective stimulation and/or neuromodulation of one or more dorsal root ganglia through implantation of an electrode on, in or around a dorsal root ganglia. Some other embodiments of the present invention provide methods for selective neurostimulation of one or more dorsal root ganglia as well as techniques for applying neurostimulation to the spinal cord. Still other embodiments of the present invention provide stimulation systems and components for selective stimulation and/or neuromodulation of one or more dorsal root ganglia through implantation of an electrode on, in or around a dorsal root ganglia in combination with a pharmacological agent. | 11-08-2012 |
20120283698 | SYRINGE GUARD WITH SELECTED NEEDLE CONFIGURATIONS - A device for expelling a fluid through a needle mounted on a hub includes an elongated luer member that has a distal portion dimensioned to engage the needle hub to provide fluid communication between the luer member and the needle. An adapter anchors the luer member within the device. Slidingly mounted on the adapter is a cylindrical-shaped inverted plunger that is movable thereon between an advanced position and a withdrawn position. A needle guard is biased by a biasing member to extend distally from the luer member when the plunger is in the advanced position. The guard is selectively engageable with the plunger to be retracted to expose the distal portion of the luer member for fluid engagement with the needle hub when the plunger is moved to the withdrawn position. | 11-08-2012 |
20120289929 | Drive Mechanisms Suitable for Use in Drug Delivery Devices - The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device. | 11-15-2012 |
20120289930 | AUTOMATIC-LOCKING SAFETY NEEDLE COVERS AND METHODS OF USE AND MANUFACTURE - A single-use needle cover configured to obscure, protect, or hide at least a portion of a needle from view before, during, and/or after an injection and/or aspiration procedure is disclosed. In some embodiments, the cover includes a housing at least partially containing the needle and configured to couple to a syringe, wherein the housing includes an axis and a guide member. In some embodiments, a sleeve has a plurality of tracks configured to slidingly receive the guide member, wherein the sleeve is configured to retract, extend, and rotate with respect to the housing. In some embodiments, after the sleeve has been retracted and extended one time, a first locking member inhibits further retraction of the sleeve and a second locking member inhibits rotation of the sleeve. | 11-15-2012 |
20120289931 | MEDICAMENT KIT AND METHOD OF USE - A medicament delivery system and method of use. A medicament delivery system comprising a medicament, a medicament delivery device, an alerting device, operating instructions, and a carrying case. The medicament can be glucagon for use with Type 1 diabetics. A method where a person assisting a patient in medical distress locates the patient's medicament injection pen by using an alerting device that sends a signal to the pen's carrying case, and where a triggered alarm in the case alerts the assisting person of the pen's whereabouts. A method where a person assisting a patient in medical distress provides a medicament to the patient by pushing an actuator on a medicament injection pen until a diaphragm separating two chambers in the pen breaks allowing medicament and diluting solution to mix, and where the assisting person then injects the mixture into a soft tissue of the patient. | 11-15-2012 |
20120289932 | DEVICE AND METHOD FOR COMBINING A TREATMENT AGENT AND A GEL - A method including introducing a treatment agent at a treatment site within a mammalian host; and introducing a bioerodable gel material at the treatment site. An apparatus including a first annular member having a first lumen disposed about a length of the first annular member and a first entry port at a proximal end of the first annular member, and a second annular member coupled to the first annular member having a second lumen disposed about a length of the second annular member and a second entry port at a proximal end of the second annular member, wherein the first annular member and the second annular member are positioned to allow a combining of treatment agents introduced through each annular member at the treatment site. | 11-15-2012 |
20120302992 | PNEUMATIC INJECTOR - This document discloses, among other things, an air-powered auto-injector device for subcutaneous delivery of a rescue drug. The device is configured for self-administered treatment of anaphylactic shock. Air is compressed by relative movement of a piston and a cylinder and released to subcutaneously drive an hypodermic needle. | 11-29-2012 |
20120302993 | ANESTHETIC DELIVERY DEVICE - According to an example embodiment, a delivery device may include a needle and a pump operatively coupled to the needle, the pump having an expanded configuration and a collapsed configuration, the pump being biased to its expanded configuration such that fluid stored in the pump will exit the pump via the needle in response to pressure being applied to the pump, and in response to the pressure being released from the pump, the pump is configured to receive fluid from outside of the delivery device via the needle. | 11-29-2012 |
20120302994 | THROUGH TIP FOR CATHETER - Catheter having an elongate tubular shaft including an inflation lumen and a guidewire lumen defined therein, the guidewire lumen extending along at least a distal length of an inner tubular member of the elongate tubular shaft. The catheter includes a distal tip member having a proximal end and a distal end, wherein the distal tip member is monolithic and the proximal end of the distal tip member is secured to a distal end of the inner tubular member. The catheter includes a balloon having a proximal portion and a distal portion, the proximal portion of the balloon sealingly coupled to the distal portion of the elongate tubular shaft. The distal portion of the balloon is sealingly coupled to the distal tip member and the balloon defines an inner chamber in communication with the inflation lumen, wherein the proximal end of the distal tip member is disposed within the inner chamber. | 11-29-2012 |
20120310206 | Injection Device - An injection device ( | 12-06-2012 |
20120310207 | SYRINGE WITH NEEDLE GUARD INJECTION DEVICE - The present invention provides for an injection device including a syringe with a proximal end, a distal end, a needle extending from the distal end, and a plunger inserted into the proximal end. A guard is slidable on the syringe, has a proximal end, a distal end, and is biased from a first position wherein the needle is exposed towards a second position wherein the guard covers the needle. The injection device includes first and second sets of cooperating detents for retaining the guard and syringe in the first and second positions, respectively. A latch member extends proximally from the guard that is engageable by the plunger as the plunger is depressed to release the first set of cooperating detents. Upon release, a spring element biases the guard towards the second position until the second set of cooperating detents engage and secure the guard in the second position. | 12-06-2012 |
20120310208 | DEVICE FOR ADMINISTERING A FLUID PRODUCT - An administering device for a fluid product includes a product receptacle that accommodates the product to be administered, a fluid reservoir for a driving fluid, a driving means, a product chamber, and a fluid connection. The product receptacle includes an opening at a forward end and a product stopper at a rear end. The driving means acts upon the fluid reservoir, the pressure chamber adjoins the product stopper while the fluid connection is located between the fluid reservoir and the pressure chamber, and the driving means acts upon the fluid reservoir in such a way that the pressure chamber is impinged upon by pressure which affects the product stopper and the product is discharged from the product receptacle. | 12-06-2012 |
20120323216 | NEEDLESHIELD ASSEMBLY - A needleshield assembly including a needle hub, hypodermic needle and protective cover is disclosed in which the protective cover can both secure and disable the needle following use. | 12-20-2012 |
20120323217 | Cranial Evacuation System and Use Thereof - The present invention relates to a method and device for removing solid matter from a brain and controlling bleeding associated with the removal of the matter. The method involves securing a cranial anchor to a region of the skull in which an opening has been created to expose brain matter and introducing through a passage defined by the anchor a channel member that displaces brain tissue and exposes the solid matter. After removing the solid matter, a flowable hemostat is introduced into the cavity created by removal of the matter. A balloon introduced into the working channel is then inflated to compress the hemostat against the wall of the cavity to control bleeding from blood vessels around the cavity. The device includes a cranial anchor, a channel member defining a working channel, an optional removable trocar, and a catheter for introducing the hemostat and the inflatable balloon into the cavity. | 12-20-2012 |
20120323218 | DRUG-DELIVERY PUMPS AND METHODS OF MANUFACTURE - Embodiments of an implantable electrolytic pump include an electrolysis chamber, a drug chamber and an osmosis chamber, the osmosis chamber having a first portion in contact with the drug chamber and a second portion exposed to facilitate contact with a surrounding fluid. The pump further includes a cannula for conducting liquid from the drug chamber and electrolysis electrodes within the electrolysis chamber for causing generation of a gas therein, the electrolysis and drug chambers being in contact such that gas electrolysis within electrolysis chamber forces fluid from the drug chamber into the cannula, contact between the drug chamber and the osmosis chamber permitting fluid admitted into the osmotic chamber from the surrounding fluid to offset volume loss from the drug chamber and prevent buildup of vacuum pressure thereon. | 12-20-2012 |
20120323219 | DELIVERING DRUGS TO DESIRED LOCATIONS WITHIN A MAMMAL - This document provides materials and methods related to delivering drugs to desired locations within a mammal. For example, materials and methods for implanting a guide wire and a drug eluting implant into a mammal are provided. | 12-20-2012 |
20120330275 | Syringe Evacuator - A syringe evacuator configured to discharge a syringe at a controllable rate. In one embodiment, the syringe evacuator includes a threaded shaft and a syringe depressor platform threaded onto the threaded shaft. The syringe evacuator also includes a spiral spring coupled to the threaded shaft configured to rotate the threaded shaft. | 12-27-2012 |
20130006216 | LOW DOSE PREFILLED DRUG DELIVERY DEVICE AND METHOD - A drug delivery device ( | 01-03-2013 |
20130006217 | METHOD OF DRUG DELIVERY FOR PTH, PTHrP AND RELATED PEPTIDES - The present invention provides compositions, devices, methods and processes related to the intradermal delivery of PTHrP and PTHrP analogues, particularly [Glu | 01-03-2013 |
20130006218 | Assisted Injection Device - Assisted injection device including a container for containing a product to be injected, the container including a movable bottom; a needle attached to the end of the container opposite the movable bottom; a piston acting on the movable bottom to expel through the needle a product located in the container and which is to be injected; a rotary motor for moving the piston by means of a drive mechanism, which converts the rotary motion of the rotary motor into a linear motion of the piston, the piston acting on the movable bottom by means of a compressible damping element. | 01-03-2013 |
20130006219 | LOW-PROFILE MICRONEEDLE ARRAY APPLICATOR - An applicator used to apply microneedle arrays to a mammal In particular, an application device for applying a microneedle device to a skin surface comprising a flexible sheet having a raised central area attached to the microneedle device and a supporting member at or near the periphery of the flexible sheet, wherein the flexible sheet is configured such that it will undergo a stepwise motion in the direction orthogonal to the major plane of the sheet. | 01-03-2013 |
20130012918 | STEADY GRIP OPHTHALMIC SURGICAL SYRINGE AND METHOD - A disposable hypodermic syringe for stable one-handed dispensing of fluids and precision positioning comprises a hollow barrel for retaining fluid. The barrel has proximal end, a midpoint, and a distal end, and a proximal end. At least one forward barrel flange is fixedly formed around or connected to the barrel and positioned at a point between the midpoint and the distal end of the barrel. | 01-10-2013 |
20130012919 | RETROBULBAR SYRINGE AND METHODS OF USE - A device useful for making retrobulbar injections includes an inner syringe contained within an outer syringe. A spring retained within the outer syringe biases the inner syringe proximally, which a catch mechanism on the two syringes prevents the inner syringe from moving out of the outer syringe. A distal needle on the inner syringe is movable within a distal sheath of the outer syringe, and can be extended beyond the distal end of the sheath to permit the device to piece more resilient tissues, and can be withdrawn by action of the spring within the sheath to protect more delicate tissues from the needle. | 01-10-2013 |
20130018356 | CHARACTERIZING MEDICATION CONTAINER PREPARATION, USE, AND DISPOSAL WITHIN A CLINICAL WORKFLOW - Data characterizing a medication container (e.g., an identifier, etc.) is received from a manually administrable medication device within a clinical workflow. Thereafter, one or more data records are generated, modified, or appended to include a portion of the received data. Subsequent requests that include the medication source from remote sources are answered by transmitting data stored in the one or more data records. Related apparatus, systems, methods, and articles are also described. | 01-17-2013 |
20130018357 | MEDICATION RESERVOIR - A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. A base is provided which is adapted to receive a reservoir. The base has a base engagement member, such as a detent, projecting therefrom. A cap is provided which is adapted to receive the base. The cap includes a first cap engagement member, such as a detent opening, which is adapted to removably engage the base detent. The cap further includes a second cap detent opening which is adapted to removably engage the base detent. A piercing member, such as a needle, is disposed in the interior of the cap in such a manner that the needle is separated from the reservoir septum when the base detent is in the first cap detent opening, and the needle pierces the reservoir septum when the base detent is in the second cap detent opening. When the reservoir, the base and the cap are connected to form an integrated unit, this unit is then capable of being inserted and secured in the infusion pump housing. | 01-17-2013 |
20130023851 | System and method for administering medicaments to a patient - The invention relates to a system and method for administering medicaments to a patient. The system comprises: a mobile medicament container with a liquid medicament; an identification-element-generating device for generating a first identification element with first data relating to the patient, medication and/or treatment, in order to apply this identification element to the medicament container; a reading device for reading the first data; a delivery device for delivering the medicament to the patient from the medicament container inserted into the delivery device, wherein the reading device is suitable for reading second data provided on/in a second identification element assigned to the patient and connected to the delivery device, and a control device within the delivery device sends a first control signal for activating the delivery process to at least one of a plurality of delivery units of the delivery device if the first and second data at least partially match. | 01-24-2013 |
20130030409 | DRUG DELIVERY DEVICE, ASSEMBLY FOR A DRUG DELIVERY DEVICE AND METHOD FOR SETTING UP A DRUG DELIVERY DEVICE - The instant application is directed to an assembly for a drug delivery device which is arranged to operate in two distinct modes, a priming mode starting from a pre-priming state and a dispense mode operating in a post-priming state, and a drug delivery device comprising this assembly. The assembly comprises a dose member, an actuating member and a piston rod which is configured to act on a bung of an assembled cartridge containing the drug. In the pre-priming state the actuating member is configured to be moved by a user such that the movement of the actuating member causes a movement of the dose member and such that the movement of the dose member causes a movement of the piston rod. In the post-priming state the dose member is configured to be moved by a user without causing a movement of the actuating member in order to perform a set and dispense action of the drug delivery device. | 01-31-2013 |
20130035664 | DUAL CHAMBER MIXING DEVICE FOR A SYRINGE - A mixing device and a retractable syringe comprising same are provided. The mixing device comprises concentric outer and inner barrels that form an outer chamber, the inner barrel having an inner chamber. A mixing plunger is slidably located in the outer chamber. A seal located in the outer chamber is capable of axial movement, in response to depression of the mixing plunger, from a first position in sealing engagement with one or more apertures in the inner barrel to a second position intermediate the apertures and vents in the outer barrel. This allows depression of the mixing plunger to force a first substance from the outer chamber through the apertures to mix with a second substance in the inner chamber. The mixed substance in the inner barrel is then delivered by the syringe with subsequent needle retraction. | 02-07-2013 |
20130041344 | Medication Delivery Device and Method for Dispensing a Medication - A medication delivery device ( | 02-14-2013 |
20130041345 | STERNAL LOCATORS AND ASSOCIATED SYSTEMS AND METHODS - Apparatuses, systems, and methods for sternal locators for placement of an intraosseous device into the sternum of a human patient. | 02-14-2013 |
20130041346 | LOW VOLUME ACCURATE INJECTOR - Substance-administration apparatus ( | 02-14-2013 |
20130041347 | MEDICAMENT DELIVERY DEVICE - The present invention relates to a medicament delivery device comprising a drive means configured to act on a medicament container for expelling a medicament; a holding means configured to hold said drive means in a pre-tensioned state; an activation means configured to interact with said holding means for releasing said drive means from the pre-tensioned state; wherein the device further comprises feedback means configured to interact both with said holding means and with said drive means for generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled. | 02-14-2013 |
20130060229 | DEVICES, SYSTEMS, AND RELATED METHODS FOR DELIVERY OF FLUID TO TISSUE - A fluid delivery system including a first balloon and a second balloon at least partially positioned within the first balloon, wherein the second balloon has an inner surface, an outer surface, and at least one micro-needle extending outwardly from the outer surface of the second balloon. The delivery system can further include a fluid source in communication with at least one of the micro-needles of the second balloon. | 03-07-2013 |
20130060230 | INJECTABLE FILLERS FOR AESTHETIC MEDICAL ENHANCEMENT AND FOR THERAPEUTIC APPLICATIONS - The present invention relates to a biocompatible injectable filler composition comprising calcium phosphate particles having a porosity of about 10% to about 90%, a BET surface area of about 1 m | 03-07-2013 |
20130060231 | AUTO-INJECTOR FOR RETRACTABLE PREFILLED SYRINGE - An actuation mechanism for an automatic injector includes a first actuation spring, a first actuation pill, a second actuation spring, and a second actuation pill. In an initial configuration the first actuation spring resides in a compressed, energized state substantially within an upper portion of first actuation pill and the second actuation spring resides in a compressed, energized state between the first actuation pill and the second actuation pill. An automatic injector includes a housing, an activation mechanism, an actuation mechanism, and a syringe cartridge having a plunger and a needle assembly. A retractable syringe may be utilized as a syringe cartridge, such as a prefilled retractable syringe with integrated safety features which retract the needle after use. The automatic injector may be utilized to inject the needle, deliver a drug treatment, and activate retraction of the needle. Methods of assembly and operation are also provided. | 03-07-2013 |
20130060232 | AUTOMATIC RECONSTITUTION FOR DUAL CHAMBER SYRINGE - An automatic mixing device, an actuating device removably mounted to the automatic mixing device and a retractable syringe having the automatic mixing device are provided. The actuating device has an initially compressed spring and a trigger member that initiates spring decompression to drive depression of a mixing plunger of the automatic mixing device. A seal located in the outer chamber is capable of axial movement upon depression of the mixing plunger, from a first position in sealing engagement with one or more apertures in an inner barrel to a second position intermediate the apertures and vents in an outer barrel. This allows depression of the mixing plunger to force a first substance from the outer chamber through the apertures to mix with a second substance in an inner chamber of the inner barrel. The mixed substance in the inner barrel is then delivered by the syringe with subsequent needle retraction. | 03-07-2013 |
20130060233 | INSERTION MECHANISM FOR A DRUG DELIVERY PUMP - An insertion mechanism for a drug pump includes an insertion mechanism housing; a manifold guide; an insertion biasing members initially held in an energized state; a retraction biasing member and a hub connected to a proximal end of a needle, wherein the retraction biasing member is held initially in an energized state between the hub and the manifold guide; and a manifold having a septum and a cannula, wherein the annular space between the septum and the cannula defines a manifold header. The needle and cannula are inserted into the body of a user by the insertion biasing member(s), after which only the needle is retracted. Retraction of the needle may open a fluid pathway from the manifold header to the body through the cannula. A drug delivery pump includes an activation mechanism, a drive mechanism, a fluid pathway connection, and the insertion mechanism. Assembly and operation methods are provided. | 03-07-2013 |
20130072900 | APPARATUS AND METHOD FOR SAFELY INSERTING AN INTRODUCER NEEDLE INTO EPIDURAL SPACE - An epidural needle assembly is provided, permitting the accurate introduction of a large bore introducer sleeve needle into the epidural space in the spinal column of a patient using the loss of resistance technique. The large bore introducer needle has a beveled side opening at its tip and with a tissue piercing point at the distal extension of the needle. A syringe needle is received within the introducer needle with a distal head of the syringe needle filling the beveled side opening at the distal end of the introducer needle when the syringe hub is fully seated. The lumen of the syringe needle exits the syringe needle head at the side opening of the introducer needle immediately adjacent the tissue piercing point of the introducing needle. The needle assembly may be inserted and advanced, with precise tactile feedback, into a patient, thus accurately detecting the introduction of the introducer needle into epidural space. | 03-21-2013 |
20130072901 | Fixation and Protection of an Implanted Medical Device - Fixation and protective components for use with implantable medical devices, such as access ports and catheters, are disclosed. In one embodiment, a protective sleeve is employed about a catheter so as to distribute compressive loads and ensure patency of the catheter lumen, even in areas prone to pinch-off. A catheter assembly in one embodiment thus comprises an elongate catheter tube that defines at least one lumen. A protective mesh sleeve is disposed about an external portion of the catheter tube so as to cover at least a portion of the longitudinal length of the catheter tube. The protective sleeve is configured to distribute a compressive load on the catheter tube so as to ensure patency of the at least one lumen of the catheter tube. | 03-21-2013 |
20130072902 | MICRONEEDLE ASSEMBLY FORMULATION FOR SKIN TREATMENT - A problem to be solved of the present invention is to provide a drug formulation and a method of administering an active ingredient which allow the active ingredient to be delivered evenly into the site of action in the skin with high efficiency while ensuring stability of the active ingredient over a long time, and which are easily handled and are less stressful for patients. Mean for solving the problem is a microneedle assembly formulation for skin treatment comprising a platform and a plurality of conical or pyramidal microneedles formed on the platform containing a base composed of a bio-soluble and thread-forming polymer substance and an objective substance retained in the base, wherein the objective substance is a substance effective for prevention or treatment of skin senescence, or treatment of skin scar. | 03-21-2013 |
20130079746 | INTRODUCER SHEATH WITH THIN-WALLED SHAFT - A thin-walled introducer sheath is described. In some embodiments, the introducer sheath includes structural support components, such as wires, used in connection with a polymeric inner coating, a polymeric outer coating, or both. Further, in some embodiments, the wire components are annealed to reduce cold-work-related stresses and hardness. Use of annealed components may enable a reduction in the thickness of the polymeric outer coating in some applications. | 03-28-2013 |
20130079747 | DRUG DELIVERY DEVICE - A drug delivery device having a housing containing a gas generator controlled by an electronic controller. The gas generator generates gas into a reciprocable chamber, whereby reciprocation of the chamber causes a lever to reciprocate a pawl, and this action causes a ratchet to The device may also be provided with manually control for delivering a bolus dose of drug when necessary. | 03-28-2013 |
20130079748 | STEPPED CANNULA - Described herein are cannulas having a stepped exterior. Also described are methods of making and using these cannulas, for example to deliver one or more materials to the central nervous system of an animal. | 03-28-2013 |
20130085472 | MICRONEEDLE NASAL DELIVERY DEVICE - The invention is directed to a nasal delivery device comprising one or more microneedles, and to methods of nasally administering a composition with a nasal delivery device comprising one or more microneedles. In certain embodiments, the nasal delivery device comprises a substrate for administration of a composition to the nasal and/or sinus mucosa, wherein the substrate is non-absorbent and comprises one or more microneedles. In some embodiments, the nasal delivery device comprises a reservoir comprising one or more therapeutic agents, wherein the reservoir is in fluid communication with one or more microneedles. | 04-04-2013 |
20130096531 | HYPODERMIC NEEDLE ASSEMBLY HAVING A TRANSITION HUB FOR ENHANCING FLUID DYNAMICS AND MICROSPHERE INJECTABILITY - A hypodermic needle assembly and a method of delivering a microsphere drug. A hypodermic needle assembly includes an injection needle; an injection device; and a hub defining a cavity including a transition portion having a first end and a second end between the first end and an inlet of the injection needle and having a gradually decreasing diameter from the first end to the second end, wherein the hub is coupled between the injection needle and the injection device such that the first end is in fluidic communication with an outlet of the injection device and the second end is in fluidic communication with the inlet of the injection needle, wherein the diameter of the cavity at the first end is larger than an outlet diameter of the injection device, and wherein the diameter at the second end is substantially the same as an inlet diameter of the injection needle. | 04-18-2013 |
20130096532 | Polymer-Based Micro-Needle Array Designs, Fabrication Processes, and Methods of Use Thereof for Drug Delivery - A micro-needle array is provided that may be used to deliver a bioactive agent to a therapeutic target. The micro-needle array preferably includes a substrate, a plurality of micro-needles integral with the substrate, and a bioactive agent. At least one micro-needle preferably includes a top surface, a bottom surface, a side surface, and a cavity defined by an inner surface. The bioactive agent may be disposed on the substrate and the plurality of micro-needles. The at least one micro-needle may further include a slit connecting the cavity to an aperture, the slit extending from the top surface to the bottom surface. A plurality of micro-needles on a patch is also disclosed for transdermal drug delivery applications. | 04-18-2013 |
20130096533 | Tissue penetration device - An agent injection device is provided that is capable of injecting an agent to a known predetermined tissue depth. An injection member has an elongate injection shaft with an outlet port configured to dispense an agent at a controllable time. A controllable driver is coupled to the elongate injection shaft and is configured to drive the injection member into target tissue. A velocity control system is in communication with the controllable driver and is configured to control the velocity of the elongate injection shaft. | 04-18-2013 |
20130096534 | Drug Delivery Systems and Methods - A delivery system includes a housing along with a tip connected to one end of the housing. A first cannula extending from the tip is provided for inserting a rod implant into tissue. A second cannula, concentrically disposed within the first cannula, is utilized to force the rod implant from the first cannula and for ejecting a fluid behind the inserted rod implant in the tissue. | 04-18-2013 |
20130102994 | SEALING ARRANGEMENT FOR SYRINGE - A syringe containing a high water content product and for use in a drug infusion system is provided. The syringe includes a plunger carrying front and rear o-rings made of a diene rubber compound such as chlorobutyl rubber or bromobutyl rubber to impart very low gas permeability characteristics to the o-rings. The plunger may be molded as a single part or in two parts. If molded as one part with radially-engaging mold portions, the seal glands in the plunger may include parting lines from the mold. If molded as two parts with axially-engaging mold portions, the front seal gland may include a sealing surface and under cut that has no parting line. The o-rings may be surface treated with a lubricant to improve sealing where the molding process gives rise to parting lines in the seal glands. | 04-25-2013 |
20130110076 | Single-Use Auto-Disable Syringe | 05-02-2013 |
20130110077 | Implant Cannula Having an Implant and a Method for Securing Implants in an Injection Cannula | 05-02-2013 |
20130110078 | Vaccination Method Using Microneedle Arrays | 05-02-2013 |
20130110079 | ACCESS NEEDLE WELL-SUITED FOR PERCUTANEOUS IMPLANTATION IN A BODY LUMEN | 05-02-2013 |
20130110080 | SYSTEMS AND METHODS FOR DELIVERING THERAPEUTIC AGENTS | 05-02-2013 |
20130116650 | DIALYSIS APPARATUS AND METHOD FOR CONTROLLING A DIALYSIS APPARATUS - Dialysis apparatus including a blood treatment unit having a dialysate chamber and a blood chamber separated by a semipermeable membrane, a dialysate circuit presenting a supply line and a discharge line connected to the blood treatment unit, a preparation device for preparing a dialysate containing a substance present in the blood too and a regulator regulating the concentration of the substance in the dialysate. A blood circuit to circulate extracorporeal blood through the blood chamber; a controller that determines a value representative of the concentration of the substance in the blood and are programmed for driving the regulator as a function of the determined value representative of the substance concentration in the blood such that the substance concentration in the dialysate tends towards the substance concentration in the blood. | 05-09-2013 |
20130116651 | CATHETER AND METHOD - The presently disclosed subject matter relates to a catheter and method. The catheter can be configured as a guiding catheter with a flexible shaft section, a hub disposed at a proximal portion of the shaft section, and a strain relief section that surrounds a predetermined proximal-side range of the shaft section. A distal end of the strain relief section can be moved along an axial direction of the shaft section at least toward the side where the hub is located. | 05-09-2013 |
20130116652 | CATHETER CANNULA WITH ANCHORING ELEMENTS, CATHETER INCLUDING THEREOF, AND/OR CATHETERIZATION METHOD USING - Catheter cannula, catheter, and catheterization method, for administering a fluid or/and substance to, or for draining a fluid or/and substance from, a treatment space of a body vessel, duct, or cavity. In some embodiments the cannula includes: an elongated flexible tube mountable on a needle, and having an invasive section and a non-invasive section; and at least one anchoring element protruding from, a surface of the invasive section in a manner such that an operative configuration of each anchoring element increases outer circumferential diameter of the cannula to an extent less than lumen diameter of the body vessel, duct, or cavity, at the treatment space, thereby anchoring the invasive section to inside the body vessel, duct, or cavity, at the treatment space. The catheter includes a needle and the cannula mounted thereupon. | 05-09-2013 |
20130123746 | TATTOO REMOVAL SYSTEM - Described is a system and associated materials and methods for delivering a fluid to a subject's skin, e.g., for tattoo removal. In one embodiment, the fluid is provided in a continuous flow by associating the fluid with a pump. In another embodiment, a disposable template is provided that allows for precise and ideal placement of eschar-inducing material fluid for, for example, tattoo removal. | 05-16-2013 |
20130123747 | Device and method for preparing tissue, particularly adipose tissue - A device and a method for preparing adipose tissue for transplantation from lobular fat extracted, for instance by liposuction, the fat including a fluid component that have an oily component, a blood component and/or sterile solutions, and a solid component including cell fragments, cells and one or more cell macroagglomerates of heterogeneous size, wherein the device includes at least one washing and separating container having a washing chamber, the container has an inlet and an outlet for the liposuctioned material to enter the washing chamber through the inlet and for at least part of the material to exit the washing chamber through the outlet, the washing chamber including stirring means for forming an emulsion of fluid components. | 05-16-2013 |
20130123748 | TOOLS AND METHODS RELATED TO CATHETER DELIVERY - A syringe adapter tool facilitates inline connection of a syringe with a catheter lumen, as well as torque transfer between the syringe and catheter. The adapter tool may further facilitate passage of an instrument through a seal zone portion of the catheter lumen, which seal zone portion is located in a proximal section of the catheter. | 05-16-2013 |
20130123749 | DRUG DELIVERY PUMP DRIVE USING LINEAR PIEZOELECTRIC MOTOR - A drug delivery pump drive which uses a linear piezoelectric motor to advance a syringe piston to deliver a liquid drug and a method thereof are disclosed. The pump drive, provided in a drug delivery pump, provides silent operation and very low energy consumption compared to electric motor-based drives. The small size of the motor helps also to reduce overall size of the pump drive and the resulting drug delivery pump. | 05-16-2013 |
20130131632 | INJECTION DEVICE AND METHOD FOR DILUTING AN INJECTABLE FLUID - An injection device enables a user to control the dilution ratio of mixed injectable fluid. In one embodiment, the injection device includes a drive unit configured to apply extrusion forces to fluids. In one embodiment, the injection device produces the mixed injectable fluid based on a selected dilution ratio. In one embodiment, the injection device produces the mixed injectable fluid based on selected injection rates. | 05-23-2013 |
20130131633 | MODULAR INJECTION SYSTEM AND METHOD FOR DILUTING AN INJECTABLE FLUID - A modular injection system enables a user to control the dilution ratio of mixed injectable fluid. In one embodiment, modular injection system includes a handheld injection device operatively connected to a separate control device. In one embodiment, the control device includes a drive unit configured to apply extrusion forces to fluids. In another embodiment, the handheld injection device includes the drive unit. In one embodiment, the modular injection system produces the mixed injectable fluid based on a selected dilution ratio. In one embodiment, the modular injection system produces the mixed injectable fluid based on selected injection rates. | 05-23-2013 |
20130131634 | Nucleus Augmentation Delivery Device and Technique - A method of performing a procedure on an intervertebral disc includes inserting a cannulated delivery tube through an opening in an annulus fibrosus of the intervertebral disc, positioning an expandable portion of the tube within the opening in the annulus fibrosus, expanding the expandable portion into contact with the annulus fibrosus about the opening to create a seal between the expandable portion and the annulus fibrosus, performing a procedure through the cannulated delivery tube within the annulus fibrosis, removing the tube, and closing the opening in the annulus fibrosus. | 05-23-2013 |
20130131635 | TISSUE TRANSFER SYSTEMS - Devices and methods for tissue transfer are described where a cannula may be inserted into the breast of a subject at one of several points of entry. Insertion of the cannula into the breast may be accomplished by using a guidance system to distinguish between tissue types. Once desirably positioned, the cannula may be withdrawn from the breast while automatically (or manually) injecting the fat in multiple deposits of adipose tissue or fat such that the deposited fat remains within the tract formed by the withdrawn cannula. Multiple tracts of the deposited fat may be injected within the breast until the breast has been desirably remodeled and/or augmented. | 05-23-2013 |
20130138078 | INFUSION PUMPS AND INSERTERS FOR USE WITH SAME - Ambulatory infusion pumps, pump assemblies, and disposable assemblies, including cartridges, baseplates, cannulas, inserters, and related components therefor, as well as component combinations and related methods. | 05-30-2013 |
20130138079 | SYRINGE AND METHOD FOR RECONSTITUTION OF DRY-FORM DRUGS AND MEDICINES - A method of reconstituting and administering an injectable fluid distributed to practitioners in dry-form includes receiving a drug or medicine in dry form, selecting a reconstitution concentration for the drug or medicine, reconstituting a desired number of units of the drug or medicine by adding diluent to the dry-form drug or medicine, selecting a syringe having units marked according to the selected reconstitution concentration, drawing up a desired number of drug or medicine units using the selected syringe, and administering a desired number of units according to the unit markings on the selected syringe. Such a syringe includes a barrel, a plunger assembly that has a plunger handle and a piston, a needle, and a needle cap. The syringe includes a visual indicia, representing a first drug concentration contained in the barrel, that is distinguishable from a corresponding visual indicia, on a second syringe, representing a second drug concentration. | 05-30-2013 |
20130144255 | SYRINGE ASSEMBLIES INCLUDING A SAFETY SHIELD FOR A NEEDLE - A safety shield for use with a hypodermic syringe device is disclosed. The safety shield is moveable relative to the syringe barrel between refracted position and a needle containing position. In the retracted position, the syringe device may be used to inject the needle into the patient. After the needle has been withdrawn or as the needle is withdrawn from the patient, in its operative mode, the shield extends from its retracted position to a needle containing position to shield the point of the needle to prevent accidental sticks and to render the syringe unuseable after a single injection. | 06-06-2013 |
20130144256 | MEDICAL MARKING APPARATUS AND METHODS - The present invention provides the materials and methods related to marking the injection site on a patient's skin. Specifically, the present invention provides the materials and methods for applying a medical marking tattoo containing at least one injecting targeting site, injecting a medical substance into the area of the injection target site, and marking the injecting targeting site using a tattoo activation element. The present invention also provides the materials and methods for a medical marking apparatus that can be used to perform the methods of the present invention to mark the injection site on a patient's skin. | 06-06-2013 |
20130144257 | DEVICE FOR DELIVERY OF RHEUMATOID ARTHRITIS MEDICATION - Disclosed are devices for delivering a rheumatoid arthritis drug across a dermal barrier. The devices include microneedles for penetrating the stratum corneum and also include structures fabricated on a surface of the microneedles to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. The pattern of structures on the surface of the microneedles may include nano-sized structures. | 06-06-2013 |
20130144258 | METHOD FOR DELIVERY OF ANTIMICROBIAL TO PROXIMAL END OF CATHETER - Systems, methods, and articles for delivering an antimicrobial composition into the lumen of a trans-dermal catheter and to proximal elements of the transdermal catheter are disclosed. In an embodiment, the system comprises an elongate member configured for insertion into a lumen of a catheter, the elongate member containing an antimicrobial. In an alternative embodiment, an antimicrobial composition placed on an interior surface a cap element, and transfers antimicrobial to the exterior of the proximal end of the transdermal catheter. | 06-06-2013 |
20130144259 | Catheter having proximal heat sensitive deflection mechanism and related methods of use and manufacture - Deflectable catheter systems, apparatuses and methods utilizing thermal expansion to influence catheter deflection. A representative embodiment includes a catheter having one or more pull wires or other tensioning elements. One end of the tensioning element(s) is connected at a distal portion of the catheter to facilitate shaft deflection upon pulling the tensioning element(s). A heat-sensitive control member(s) is coupled to a proximal portion of the tensioning element(s). The elongate tensioning element(s) is pulled in a proximal direction to deflect the distal portion of the catheter in response to a temperature change applied to the heat- sensitive control member. | 06-06-2013 |
20130144260 | DEVICE AND METHOD FOR THE CONTROLLED DELIVERY OF OPHTHALMIC SOLUTIONS - The present disclosure is directed to an injector device for delivering an ophthalmic solution to a cornea of an eye. The device may include a base configured to contact part of the eye, and a needle connected to the base, wherein needle may deliver the ophthalmic solution to the cornea. | 06-06-2013 |
20130144261 | STRUCTURES FOR TRANSDERMAL DRUG DELIVERY - A preparation for the transdermal delivery of a biologically active substance into the body of a patient comprises particles of a formulation comprising the active substance. The particles are irregular in size and shape and may be produced by a low cost manufacturing method such as grinding from a thin film. The particles are angular, i.e. they have sharp edges and corners that allow them to penetrate the outer layer of the skin when subjected to pressure from a roller or an array of blunt-tipped microstructures. Sucrose may be used as an excipient with the active substance to form suitably rigid and angular particles. | 06-06-2013 |
20130144262 | Package for Delivering Microdoses of Medicament - A primary package for simultaneously dispensing microdoses of from 5 to 500 microliters of one medicament contained in a medicated module and another medicament contained in an attached injection system is disclosed, where the primary package contains a single dose of medicament contained within a reservoir cavity sealed with closure caps that secure top and bottom septa. | 06-06-2013 |
20130150825 | TISSUE TRANSFER SYSTEMS - Devices and methods for tissue transfer are described where a cannula may be inserted into the breast of a subject at one of several points of entry. Insertion of the cannula into the breast may be accomplished by using a guidance system to distinguish between tissue types. Once desirably positioned, the cannula may be withdrawn from the breast while automatically (or manually) injecting the fat in multiple deposits of adipose tissue or fat such that the deposited fat remains within the tract formed by the withdrawn cannula. Multiple tracts of the deposited fat may be injected within the breast until the breast has been desirably remodeled and/or augmented. | 06-13-2013 |
20130150826 | APPARATUS AND METHOD FOR TRANSDERMAL DELIVERY OF BIOACTIVE SOLUTION - Apparatus for transdermal or subcutaneous delivery of a bioactive solution, including a plurality of needles fixed on a needle carrier in a spaced apart relationship and projecting from the needle carrier, each needle having a tip zone adapted to receive an amount of bioactive solution from a reservoir coupled to the needle carrier and to deliver the bioactive solution upon penetrating a skin. | 06-13-2013 |
20130150827 | MEDICAL DEVICE SECUREMENT SYSTEM - A securement device, system, and method for use with a medical article. The securement device, system, or method may include a body that has a top surface and a bottom surface. The bottom surface has an adhesive compound thereon. A resilient retainer formed from a soft, tacky elastomeric gel or foam is supported by the bottom surface of the body. The resilient retainer receives and secures a medical device. The medical device is secured to the skin of a patient upon affixing the bottom surface to the patient via the adhesive compound. | 06-13-2013 |
20130158505 | MEDICAL DEVICES FOR DELIVERY OF siRNA - Disclosed are medical devices that incorporate siRNA. In addition to one or more siRNA constructs, devices include nanostructures fabricated on a surface to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. Microneedles may be incorporated on devices. The pattern including nanostructures may be formed on the surface of the microneedles. | 06-20-2013 |
20130158506 | CATHETER AND NEEDLE SYSTEM AND METHOD OF INSERTING A CATHETER - A system and method for inserting a catheter into a patient, the system comprising a frame including a catheter hub configured to provide a first anchoring point on a patient and receive a catheter insertable in the patient at an insertion site, a stabilization hub configured to provide a second anchoring point on the patient, and a flexible tubular lateral member, extending between the catheter hub and the stabilization hub; a fluidic channel configured to fluidically communicate with the catheter and transfer fluid to the catheter; a flush fluid source configured to couple to the fluidic channel and supply flush fluid to the catheter; a housing comprising a needle mount and a flash chamber; and needle having a distal end insertable through the frame and the catheter and a proximal end coupled to the needle mount, wherein the needle is configured to provide a fluid path to the flash chamber. | 06-20-2013 |
20130158507 | Biliary System Catheter - A catheter system and a method for accessing the bile duct are provided. The catheter system includes an elongate shaft having a proximal portion and a distal portion. The catheter also includes a first lumen extending at least partially through the elongate shaft, a distal portion of the first lumen extending generally parallel to a longitudinal axis of the elongate shaft and a distal port operably connected to the first lumen. The catheter system also includes a second lumen extending at least partially through the elongate shaft and a side port operably connected to the second lumen, the side port positioned proximal to the distal port and operably connected to the second lumen. The second lumen includes an angled wall portion adjacent to the side port. A marker is included on the distal portion of the elongate shaft, the marker configured to indicate the position of the side port. | 06-20-2013 |
20130158508 | MULTIPLE DOSAGE INJECTOR - A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion. | 06-20-2013 |
20130165902 | MICRONEEDLE ARRAY APPLICATOR AND METHOD FOR APPLYING A MICRONEEDLE ARRAY - A microneedle array applicator is configured to apply a microneedle array in cosmetic and medical applications. The microneedle array applicator has a holding apparatus configured to define detachable holding of a microneedle array comprising a planar substrate. The microneedle array applicator also has a drive mechanism for driving the microneedle array in a first direction perpendicular to the planar substrate and in a second direction parallel to the planar substrate. A method for applying a microneedle array includes the microneedle array applicator enabling safe breaking off of the microneedles, optionally laden with an active ingredient, in the skin. | 06-27-2013 |
20130172850 | APPARATUS AND METHOD FOR DISPENSING BONE CEMENT - An apparatus and method for dispensing bone cement includes a cartridge for containing the bone cement. The apparatus also includes a plunger insertable into the cartridge. An impedance sensor is coupled to the plunger and configured to produce an output signal indicative of an impedance of bone cement contained in the cartridge. The apparatus may also include a processing circuit configured to determine an impedance value of bone cement contained within the cartridge based on the sensor signal. The processing circuit may activate a visual indicator based on the impedance value to indicate that the dough time, the end-of-work time, and/or setting-time of bone cement contained in the cartridge has been reached. | 07-04-2013 |
20130178822 | DELIVERY AND EXTRACTION DEVICES - This invention provides a device for delivering substances such as medical implants and tissues. The device comprises a mandrel and a mandrel guide whereby substances are delivered by retracting the mandrel guide relative to the mandrel. Included among the various embodiments are devices specialized for delivering retinal pigment epithelial (RPE) cells or nanoplates containing RPE cells to the retina, devices with precise control of delivery, devices with specialized mandrels and/or nozzles, and multifunctional devices adapted to provide additional functions such as infusion and/or suction, illumination, and diathermy. | 07-11-2013 |
20130178823 | AUTOMATIC MIXING DEVICE AND DELIVERY SYSTEM - A wet/dry auto-mixing injector having a mixing device containing at least one microfluidic channel for mixing or dissolving a dry component with a wet component stored in the injector device. | 07-11-2013 |
20130178824 | RENAL NERVE DENERVATION VIA THE RENAL PELVIS - Apparatus, systems, and methods provide access to the renal pelvis of a kidney to treat renal nerves embedded in tissue surrounding the renal pelvis. Access to the renal pelvis may be via the urinary tract or via minimally invasive incisions through the abdomen and kidney tissue. Treatment is effected by exchanging energy, typically delivering heat or extracting heat through a wall of the renal pelvis, or by delivering active substances. | 07-11-2013 |
20130178825 | CATHETER-DRESSING SYSTEMS WITH INTEGRATED FLUSHING MECHANISMS - Methods and devices are disclosed herein that generally involve a sterile catheter-dressing system that allows for integrated injection of fluids, e.g., a saline flush, during the process of catheter insertion and sterile dressing placement. Such methods and devices can be used as a fully integrated catheter insertion system, or to convert existing catheter insertion devices and methods into integrated flush and sterile sealing catheter-dressing systems. Such methods and devices can greatly simplify the catheter insertion process, and can allow the reproducible placement of a fully sterile and flushed vascular catheter, as well as the placement of a durably sterile circumferentially sealing and securing dressing. | 07-11-2013 |
20130178826 | ACCURATE FLOW CONTROL IN DRUG PUMP DEVICES - The accuracy of drug delivery with drug pump devices may be improved by a combination of pump operation at high flow resistances and pump pressures, pressure-relief mechanisms, and sensor-based feedback for pump control. | 07-11-2013 |
20130178827 | COMPOSITIONS AND METHODS FOR TREATING JOINTS - Compositions and methods are provided for treating joint conditions, such as osteoarthritis and/or the pain associated therewith. The compositions and methods utilize a first component, namely hyaluraonic acid (“HA”), in combination with a lyophilized second component that is effective to at least temporarily reduce the viscosity of the HA. In an exemplary embodiment, the second component is one or more glycosaminoglycans (“GAG”), such as chondroitin sulfate (“CS”), including CS4 and/or CS6, dermatan sulfate, heparin, heparan sulfate, and keratan sulfate. The composition can optionally include other joint supplements, such as glucosamine (“GlcN”) | 07-11-2013 |
20130178828 | DEVICE FOR MEDICAL TREATMENT - A medical treatment device enables an injection needle to accurately puncture brain tissue at a prescribed position and a drug solution to be injected into brain tissue, while avoiding damage to the brain tissue as the injection needle is handled. The use of the medical treatment device involves inflating a first balloon located on the outside of a catheter, directing a distal portion of a puncture needle, which is located inside the catheter, to outside the catheter through an opening in the catheter, after which the first balloon is deflated and a second balloon is inflated, and moving the catheter towards the brain tissue located on the opening side so that the injection needle projecting from the opening punctures the brain region. | 07-11-2013 |
20130178829 | METHODS OF TREATING MEDICAL CONDITIONS BY TRANSVASCULAR NEUROMODULATION OF THE AUTONOMIC NERVOUS SYSTEM - The present invention is directed to a method of treating a respiratory or pulmonary condition in a patient by transvascular neuromodulation of an adrenal gland or neural structures that innervate the adrenal gland or components thereof. Methods also include implanting a controller in the patient to control delivery of a therapy signal to the patient's adrenal gland. The therapy signal can be an electrical and/or chemical signal. | 07-11-2013 |
20130178830 | DEVICES FOR TRANSDERMAL DRUG DELIVERY - A transdermal drug delivery device comprises needles or other means for piercing the skin of a patient to form pores in a predefined pattern; and carriers in the same pattern that may be loaded with a drug for delivery. Means are provided for applying the carriers to the pores to deliver the drug through the pores to a location beneath the surface of the skin. The carriers may remain outside the pores, be introduced into the pores after the needles have been removed, or be inserted alongside the needles while they are still in place. | 07-11-2013 |
20130184675 | Infusion Monitoring Device and Method for Monitoring the Infusion Dripping Rate and Alarming for the Irregularities of the Infusion - The present invention discloses an intravenous infusion monitoring device for monitoring the infusion dripping rate. This device is attached to an infusion tube above the dripping chamber, including two polar plates forming a capacitor, a capacitance measurement unit electrically connected to the capacitor, a micro control unit (MCU) configured to collect data from the capacitance measure unit and analysis and display the infusion dripping rate. A method for monitoring infusion rate includes setting the infusion solution surface to a specific height in the dripping chamber so that the infusion solution in the tube is conducted and have a pulse change of the capacitance at the moment when a droplet drips down, determining the cycle of the pulse corresponding to the infusion rate and displaying the dripping rate by LCD screen, and alarming when the infusion irregularities occurs such as too fast, too slow or fully stop. | 07-18-2013 |
20130184676 | System, Method, and Apparatus for Estimating Liquid Delivery - A pump for administering an agent to a patient includes a housing, a motor, a gearbox, a sensor, and a controller. The motor may be coupled to housing. The gearbox is operatively connected to said motor. The sensor senses a rotation of said motor. The controller acts to control operation of said motor and monitor the quantity of said agent delivered to said patient. The pump also includes a pump assembly such that the pump is configured such that the pump assembly may be interchangeable from a syringe pump assembly and a peristaltic pump assembly. | 07-18-2013 |
20130184677 | Multiple Dose Syringe and Method - A multiple dose syringe has a first valve defining a first valve opening pressure and a second valve defining a second valve opening pressure. A storage chamber in fluid communication with the second valve stores multiple doses of a substance therein and includes an outlet for dispensing multiple doses of the stored substance therethrough. A compression surface is movable between first and second positions and defines a compression chamber between the compression surface and the first valve. Movement of the compression surface in a direction from the first position toward the second position dispenses substance in the compression chamber through the first valve and out of the syringe. Movement of the compression surface in a direction from the second position toward the first position causes substance to flow from the storage chamber through the second valve and into the compression chamber. | 07-18-2013 |
20130184678 | DUAL ACTION SYRINGE - In one aspect, a dual action syringe includes an external body having a distal end defining an anesthetic gel receptive concavity surrounding a needle passage through the distal end. The external body also includes a proximal end defining a plunger receptive passage. An internal body is slidably disposed in the external body. The internal body receives a needle in a distal end of the internal body and an anesthetic carpule to provide fluid flow communication between the carpule and the needle in response to pressure on the plunger. A biasing member is disposed in the external body, between the external body and the internal body, biasing a distal end of the needle away from the distal end of the external body into the external body; whereby, pressure on the plunger first moves the needle through the needle passage and subsequently provides fluid flow communication between the carpule and the needle. | 07-18-2013 |
20130190718 | BONE GRAFT DELIVERY DEVICE - Aspects of the claimed invention relate generally to devices for delivering bone graft compositions to implants that have been positioned between vertebral bodies during surgery and methods of using such devices. Embodiments of the invention provide ease of bone graft delivery in situ while providing an environment for the mixing of bone graft, insertion of the bone graft, and packing of the graft into the voids above and below the implant. | 07-25-2013 |
20130190719 | DRUG DELIVERY DEVICE WITH DRIVE MEMBER HAVING INDICATION ELEMENTS - A drug delivery device is proposed, which comprises a housing, a drive member which is movably retained within the housing, a piston rod which is operatively coupled to the drive member, wherein the drug delivery device is configured to convert movement of the drive member with respect to the housing into movement of the piston rod with respect to the drive member, wherein a surface of the drive member is provided with one or a plurality of indication elements, and wherein the drug delivery device is adapted to display at least one of the indication elements through the housing. Furthermore it is proposed to use a single member in a drug delivery device for driving movement of a piston rod of the device and for displaying dose related information to a user of the device. | 07-25-2013 |
20130190720 | BULKING AGENTS - The invention relates to bulking agents and apparatus and methods for using the disclosed bulking agents. The bulking agents can be used to treat such conditions as urinary and fecal incontinence, gastro-esophageal reflux, aneurismal blockages, and cosmetic deformities. The invention also relates to an injection method that reduces the injection pressure required to place the bulking agents. | 07-25-2013 |
20130190721 | AUTO-INJECTOR - The invention refers to an auto-injector and to a method for operating it, the auto-injector comprising of a tubular chassis; a carrier subassembly comprising a tubular carrier slidably arranged in the chassis, the carrier containing a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe; a wrap-over trigger sleeve arranged over the distal end (D) of the auto-injector; the trigger sleeve extending at least almost over the whole length of the auto-injector; a control spring arranged around the carrier; first interlock means for coupling a proximal end of the control spring to either the carrier for advancing it for needle insertion or to the chassis for needle retraction; second interlock means arranged for releasing the drive spring for injection; third interlock means arranged for coupling the chassis to the carrier for joint axial translation relative to the trigger sleeve; and fourth interlock means arranged for coupling a distal end of the control spring to either the carrier for needle retraction or to the trigger sleeve otherwise. | 07-25-2013 |
20130190722 | AUTO-INJECTOR - The invention refers to an auto-injector for administering a medicament (M) and to a method for operating it, the auto-injector comprising of a tubular chassis and a carrier subassembly, comprising a tubular carrier slidably arranged in the chassis. The carrier contains a syringe, a drive spring and a plunger for forwarding load of the drive spring to a stopper arranged in the syringe. The syringe is locked for joint axial translation with the carrier. A control spring is connectable to the carrier by first interlock means for needle insertion, wherein the whole carrier subassembly is advanced. Second interlock means are arranged for releasing the drive spring when the carrier has at least almost reached an injection depth thus delivering the medicament (M). The first interlock means are arranged for decoupling the control spring from the carrier and coupling it to the chassis for advancing it over the needle into a needle safe position. | 07-25-2013 |
20130197474 | Medicated Module Having a Double Needle Guard - A medicated module ( | 08-01-2013 |
20130197475 | INJECTOR - An injector for delivering medicament comprises a collapsible container ( | 08-01-2013 |
20130197476 | Catheter for Positioning a Wire Guide - A system and a method of positioning a wire guide are provided. The method includes inserting a wire guide in a first configuration into a lumen of a catheter, distally advancing the wire guide to a distal portion of the lumen so that a distal end of the wire guide is distal to an opening in a wall of the catheter and advancing a distal portion of the wire guide through the opening by distally advancing the distal portion relative to the catheter so that the distal end remains in the lumen as the distal portion of the wire guide extends out of the opening. The method includes advancing the distal portion of the wire guide further out of the opening so that the distal end exits through the opening so that the distal portion is distal to the distal end of the wire guide in a second configuration. | 08-01-2013 |
20130197477 | NEEDLE ASSEMBLY WITH RELEASE MECHANISM - A needle assembly comprises a body configured for attachment to a drug delivery device. The body defines a cavity. A septum is positioned within the cavity and a stopper positioned within the cavity such that the cavity, septum, and stopper define a reservoir. A double ended needle is positioned in the stopper and septum, the needle comprising a proximal end and a distal end. A release mechanism is positioned near a distal end of the body. A biasing element is positioned to drive the stopper. During a dose dispensing step, the release mechanism drives the proximal end of the needle out of the septum so that the proximal end resides in said reservoir. The biasing element may also drive the stopper proximally. | 08-01-2013 |
20130197478 | DOSE SETTING MECHANISM AND METHOD OF USING SAME - The present invention relates to a dose setting mechanism for a drug delivery device and a method of using same. The mechanism comprises a drug delivery device housing, a dose dial sleeve positioned at least partly in the housing and being rotatable during dose setting and dose delivery, a clutch rotatable during dose setting and non-rotatable during dose delivery, and a clutch nut, that is threadedly engaged with the clutch and is splined to the housing to prevent rotation of the clutch nut. | 08-01-2013 |
20130197479 | Dose Setting Mechanism and Method of Setting a Dose - A method and system for preventing delivery of less than a predetermined minimum dose of a medicament by providing a dose setting mechanism having a spindle nut and a sprung lock nut. The mechanism includes a housing and a dose dial component positioned in the housing. The dose dial component is rotatable during a dose setting step. The mechanism further includes a drive sleeve positioned within the dose dial component. The drive sleeve is configured to drive a rotatable spindle during a dose administration step. The spindle nut is coupled to the spindle and the sprung lock nut is removably coupled to the drive sleeve and rotationally fixed to the housing. In one arrangement, when the dose dial component is rotated to select a dose less than a preselected minimum dose, the sprung lock nut allows the spindle nut to rotate thereby preventing the dose from being administered. | 08-01-2013 |
20130204224 | CONTROLLING A MOTOR OF AN INJECTION DEVICE - In order to improve the energy efficiency of an injection device | 08-08-2013 |
20130204225 | SAFETY SYRINGE AND SAFETY DOSE COMBINATION KIT - Methods, apparatuses, and systems are disclosed for reducing Medical Administered Errors, (MAE) in the administration of injectable medications to patients by using a syringe device that is designed, labeled, and calibrated to decrease the risk of such errors. The syringe may be designed for a specific medication, and labeled to indicate the name of the medication for which it was designed. The syringe is calibrated to deliver a specific amount of the medication that is the appropriate dosage for a patient of a particular weight or other feature, thereby making it unnecessary for the user to perform calculations to determine the correct dosage volume for the particular patient. The syringe may also be calibrated with additional measurement scales that enable the user to verify that the correct dosage. | 08-08-2013 |
20130204226 | Pressure Actuated Catheter Valve - This invention provides catheter assemblies and methods for insertion of a catheter into a vessel. The assemblies include a resilient valve in the hub of the catheter that can be opened by pressure from a male luer fitting. The methods include piercing a vessel with the needle and catheter of the assembly, retraction of the needle component thus closing the resilient valve. Finally the catheter can be accessed by applying a male luer fitting to the catheter hub and a shoulder of the resilient valve. | 08-08-2013 |
20130204227 | Medication Injection Site and Data Collection System - A medication delivery apparatus for use with a medication container includes a housing, a fluid conduit at least partially extending within the housing and configured to deliver medication within the medication container to a patient, a medication port extending from the housing and configured to be coupled to a fluid outlet of the medication container, the medication port being fluidically coupled to the fluid conduit, and at least one sensor disposed within the housing to generate information characterizing administration of the medication for processing by a remote data collection system. The housing can have a size and shape that enables it to be supported by a first hand of a user while the user administers the medication from the medication container via the medication port using a second hand of the user. Related apparatus, systems, and techniques are also described. | 08-08-2013 |
20130204228 | PUNCTURABLE MEMBRANE FOR SAFETY SYRINGE - A safety syringe may define a variable fluid chamber and detached needle assembly. The variable fluid chamber may be hermetically sealed off from the environment or ambient air until the needle assembly is attached to a syringe body of the safety syringe. A proximal end of the variable fluid chamber is sealed off from the environment via a seal between a piston and syringe body. The distal end of the variable fluid chamber may be sealed off from the environment via a barrier covering the distal end of the syringe body. The barrier may be punctured to allow fluid to through therethrough at or about the same time when the needle assembly is attached to the distal end portion of the syringe body. | 08-08-2013 |
20130204229 | PALM ACTIVATED DRUG DELIVERY DEVICE - A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position. | 08-08-2013 |
20130211373 | Method of Managing History of Injection of Medicinal Fluid - The present invention relates to a method of managing a history of the injection of a medicinal fluid. More particularly, the present invention relates to a method of managing a history of the injection of a medicinal fluid, which is capable of managing the history of the injection of a medicinal fluid in an apparatus for injecting a medicinal fluid that automatically injects a predetermined volume of medicinal fluid into a vein or epidural space of a patient in order to manage the pain of the patient. | 08-15-2013 |
20130211374 | Injection Control Device for Proportional Injection, Extraction during the Syringe's Insertion, Retraction - An injection control device (ICD) for a syringe, injects/extracts material into/from at a rate controllably proportional to the rate of movement of the syringe. The device has body with a first and opposite second side, syringe holder, first aperture in the first side to accommodate a cannula of the accommodated syringe, second aperture in the first side, and third aperture in the second side. A positionable transmission reference member may be linearly extendable from the second aperture; a spooling rotating member with an axle is coupled to the body; a clutch is coupled to the rotating member; and a transmission system is interior to and coupled to the body which translates body motion, in relation to a fixed state of the reference member, to move the plunger of the syringe, causing injected/extracted of material into/from a subject as the syringe's cannula is traveling with the moving body. | 08-15-2013 |
20130211375 | Syringe Devices, Components of Syringe Devices, and Methods of Forming Components and Syringe Devices - Syringe assemblies are provided that can include a valve within a plunger having a fluid channel extending longitudinally therethrough and along the channel, the valve including a piston extending substantially normally to the channel and configured to slidably engage the plunger along the extension. Syringe assemblies can also include: a syringe barrel having a first cross sectional diameter; a syringe piston configured to operatively couple with the barrel; a fluid channel extending the length of the piston; a vial port extending from an end of the piston, the vial port having a second cross sectional diameter, the second diameter being greater than the first diameter. Methods for controlling fluid along a fluid channel within a syringe plunger are also provided. The methods can include extending a piston in one direction normally to the fluid channel to provide fluid communication between two sections of the fluid channel. | 08-15-2013 |
20130211376 | CLOSURE CONTAINER FOR SINGLE DOSE DISPOSABLE PHARMACEUTICAL DELIVERY SYSTEM - Provided herein is a single dose disposable pharmaceutical delivery apparatus and methods of use and manufacture thereof. One aspect provides a single dose disposable pharmaceutical delivery apparatus that includes a needle hub seal attached to a needle hub and a bladder that can contain a pharmaceutical composition. Another aspect provides for dispensing a pharmaceutical composition from the delivery apparatus by rupturing the needle hub seal and fluidically connecting the needle and the bladder. Another aspect provides manufacturing the delivery apparatus according to steps including attaching a needle hub and a needle hub seal and combining the bladder and the needle hub, thereby forming an apparatus described herein. | 08-15-2013 |
20130211377 | Dose Setting Mechanism for a Drug Delivery Device - The present invention relates to a dose setting mechanism for a drug delivery device and a method of using same. The mechanism comprises a housing, a mechanism member movable in a first axial direction relative to the housing during dose setting and movable in a second, opposite axial direction relative to the housing during injection, wherein the mechanism member is designed and arranged such that the mechanism member is able to change its condition between a first condition preventing movement in the second axial direction and a second condition allowing movement in the second axial direction, and a switching member forcing the mechanism member to change from its second condition into its first condition at a predefined position of the movement in the first axial direction during dose setting. | 08-15-2013 |
20130218127 | Anchoring An Intravenous Cannula - Some embodiments of a medical system include a subcutaneous anchor device that extends outwardly from side wall of an intravenous cannula so as to secure the intravenous cannula in a position relative to a skin penetration point. | 08-22-2013 |
20130218128 | AUTOINJECTORS - An autoinjector includes a housing for receiving in use in a generally longitudinal loading direction a syringe assembly including a syringe carrier and a syringe, the syringe including a syringe body having a slideable internal piston for expressing a dose contained in the body through a needle at a forward end thereof; a drive mechanism for providing drive for operation of the autoinjector and being disposed generally within the housing and including a mechanical energy source and a winder element for being rotated to charge the energy source, and an input transmission train operational between the syringe assembly and the winder element in use, whereby loading of the syringe assembly into the housing rotates the winder element to charge the energy source. | 08-22-2013 |
20130218129 | Intradermal Delivery Device - A system and method is provided for an injectable substance delivery device comprising a limiter, shoulder or post that controls how deep the needle is inserted into the tissue. The limiter is sized in proportions that control the maximum insertion depth of the needle into the tissue without excessively restricting the complete insertion of the needle. The system and method further comprises an normalization or stabilizer ring that prevents distortion of the tissue in the vicinity of the infusion, so that the needle length is the major determining factor as to how deep the infusion is delivered. | 08-22-2013 |
20130218130 | Dose Setting Mechanism or Priming a Drug Delivery Device - A method and system for priming a drug delivery device. The drug delivery device includes a dose dial sleeve and an internal housing portion. The dose dial sleeve is coupled to the internal housing. The dose dial sleeve rotates on a substantially circumferential rotational path during priming of the drug delivery device. Further, the dose dial sleeve rotates on a helical path during dose setting of the drug delivery device. | 08-22-2013 |
20130226139 | METHOD AND SYSTEM FOR DETERMINING INFORMATION RELATED TO A DRUG RESERVOIR - Disclosed herein are methods and systems for detecting information related to a drug reservoir. According to one example disclosed herein, a method includes a detector feature determining an electrical property related to a coded material for a drug reservoir, wherein the coded material comprises at least one circuit. The at least one circuit may be printed onto the drug reservoir. The method further includes determining information related to the drug reservoir based at least on the determined electrical property. | 08-29-2013 |
20130226140 | Device and a system for delivery of biological material - The present invention provides a device and a system for the delivery of biological material across the biological tissue. The device may be for the programmed delivery of biological material through a needle or a micro-needle or micro-needles or biodegradable micro-needles. | 08-29-2013 |
20130226141 | Reduced Friction Catheter Introducer and Method of Manufacturing and Using the Same - Tear-away sheath introducers for catheters, methods for making such introducers, and methods for using such introducers are described. A splittable sheath introducer may include a sheath, a hub disposed at a proximal end of the sheath, a valve included with the hub, and a valve actuator movable from a first position to a second position, the valve actuator opening the valve when in the second position. The valve actuator may include a retaining member that enables the valve actuator to be retained by a portion of the hub when the sheath introducer is split apart. | 08-29-2013 |
20130226142 | BONE TREATMENT SYSTEMS AND METHODS - Systems and methods for treating bone, such as vertebral compression fractures are disclosed. A method includes controllably applying energy to a bone cement volume outside of a patient's body to selectively accelerate the polymerization rate of the bone fill material volume prior to introduction into a bone. The method further includes sequentially introducing a plurality of cement carrying structures with the accelerated polymerization rate bone cement volume into the bone. A system for use in the method includes at least one elongated cement-carrying structure sized to carry a bone cement volume therein and an energy source operatively coupleable to the cement-carrying structure. The energy source applies energy to the bone cement volume to selectively accelerate a polymerization rate thereof. An elongated injector insertable into the bone has a passageway that removably receives the elongated cement-carrying structure to allow delivery of the accelerated polymerization rate bone cement into the bone. | 08-29-2013 |
20130226143 | Medicated Module Having a Collapsible Feature - A system and method for priming a medicated module during attachment of the medicated module to a drug delivery device. The drug delivery device has a drug reservoir holding a first medicament. The medicated module includes an upper retention feature and a lower retention feature, wherein the upper retention feature is axially moveable relative to the lower retention feature. The medicated module also includes an engagement needle and an output needle, wherein the output needle is in fluid communication with the engagement needle. The module also includes a collapsible feature holding a second medicament, wherein the collapsible feature is operably connected to the upper retention feature. During attachment to the drug delivery device, (i) the upper retention feature moves axially relative to the lower retention feature, (ii) the collapsible feature collapses, and (iii) the engagement needle and the output needle are primed with the second medicament. | 08-29-2013 |
20130231633 | DEVICE FOR THE RAPID INJECTION OF LOCAL ANESTHESIA THROUGH A PLEURALITY OF NEEDLES - This device is a compressible chamber designed to inject a liquid medication through a plurality of needles. It is a self-contained, rapidly deployed device that replaces a classic syringe. It consists of a shallow chamber that is closed on one end and sealed on the other with a sliding elastomeric seal. A rigid ring slides up into the chamber that has multiple small double-ended needles mounted through the periphery of the ring perpendicularly so as to be able to perforate the seal of the chamber with the proximal end and simultaneously penetrate the subcutaneous tissues with the distal end thus allowing medication to flow from the chamber into the tissues when pressure is applied to the top of the chamber. The needles are also imbedded in, or juxtapose to a ring of compressible dye-containing material that serves to conceal the needles and provide demarcation of the area injected. | 09-05-2013 |
20130231634 | DILATION CAP FOR ENDOLUMINAL DEVICE - A dilation cap may include a distal tip, an intermediate body, and a proximal coupling member. The distal tip may at least partially surround a longitudinal axis of the dilation cap and may include a cavity to receive a distal end of a cannula of a medical device. The intermediate body may extend proximally from the distal tip and include a dilator portion. The dilator portion may include a projection extending laterally in a direction away from the longitudinal axis of the dilation cap. The proximal coupling member may extend proximally from the intermediate body and at least partially surround the longitudinal axis of the dilation cap. The proximal coupling member may be configured to engage an intermediate portion of the cannula of the medical device. The intermediate body may be asymmetrical with respect to the longitudinal axis of the dilation cap. | 09-05-2013 |
20130231635 | MULTIVOLUME CARTRIDGE ASSEMBLY AND METHOD OF MAKING THE SAME - A multivolume cartridge assembly having two or more internal compartments for storing and administering one or more medicinal compounds. In some embodiments, a second internal volume is positioned in the distal end of the cartridge assembly, and in other embodiments, the second internal volume is positioned in the apical end of the cartridge assembly. In some embodiments, the cartridge is configured to allow for long term storage of two or more medicinal compounds without mixing of the two or more compounds during storage. The cartridge, in some embodiments, utilizes a stopper assembly to create fluid communication between the two or more internal compartments of the cartridge and allow for mixing of the contents of the two or more compartments prior to the administration of those contents to a patient. | 09-05-2013 |
20130231636 | METHODS AND SYSTEMS FOR FACILITATING STIMULATION OF ONE OR MORE STIMULATION SITES - Methods and systems of facilitating stimulation of a stimulation site within a patient include implanting a distal portion of a stimulating member such that the distal portion of the stimulating member is in communication with a stimulation site located within a patient, securing the distal portion of the stimulating member at a first securing site with a first securing device, forming at least two curves of opposite concavity with a proximal portion of the stimulating member, securing the stimulating member at a second securing site with a second securing device, and coupling a proximal end of the stimulating member to a stimulator. In some examples, the at least two curves of opposite concavity are located in between the first and second securing devices. | 09-05-2013 |
20130237958 | NEEDLE STYLET AND METHODS OF IMPLEMENTATION AND MANUFACTURE - A needle apparatus and a method of implementing a needle apparatus are disclosed. The needle apparatus includes a hollow tube component including, at a first end of the hollow tube component, a pointed portion configured for piercing tissue of a patient and a needle hub disposed at a second end of the hollow tube component. The hollow tube component includes a bend disposed therein. The bend is positioned between the first and second ends of the hollow tube component. The needle apparatus also includes a stylet removably positioned in the hollow tube component. The stylet is characterized by a proximal end and a distal end. The stylet includes a stylet hub coupled to the distal end. At least a portion of the proximal end of the stylet includes a first diameter that is smaller than a second diameter of at least a portion of the distal end of the stylet. | 09-12-2013 |
20130237959 | METHOD AND A DELIVERY DEVICE FOR ADMINISTERING AN ACTIVE SUBSTANCE TO A SUBJECT - A delivery device for administering an active substance to a subject transdermally includes a first plate member having a plurality of first chambers formed therein. Solid form structures including the active substance and of conical shape having a pointed skin penetrating tip are located in the first chambers. A second plate member having a plurality of second chambers including a driving substance is secured to the first plate member with a first membrane of an expandable material sealably located between the respective first and second plate members. Expansion of the driving substance in the second chambers urges the first membrane into the corresponding first chambers for in turn urging the solid form structures to penetrate through a second membrane into the skin of the subject. A third plate member includes a plurality of electrically powered heating elements aligned with the second chambers for heating and expanding the driving substance. | 09-12-2013 |
20130237960 | INTRADERMAL DELIVERY OF SUBSTANCES - The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gauge needles, especially microneedles, placed in the intradermal space to deliver the substance to the intradermal space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient. Delivery devices which place the needle outlet at an appropriate depth in the intradermal space and control the volume and rate of fluid delivery provide accurate delivery of the substance to the desired location without leakage. | 09-12-2013 |
20130237961 | INTRADERMAL DELIVERY OF SUBSTANCES - The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gauge needles, especially microneedles, placed in the intradermal space to delver the substance to the intradermal space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient. Delivery devices which place the needle outlet at an appropriate depth in the intradermal space and control the volume and rate of fluid delivery provide accurate delivery of the substance to the desired location without leakage. | 09-12-2013 |
20130245600 | APPARATUS AND FORMULATIONS FOR SUPRACHORIDAL DRUG DELIVERY - Drug formulations, devices and methods are provided to deliver biologically active substances to the eye. The formulations are delivered into scleral tissues adjacent to or into the suprachoroidal space without damage to the underlying choroid. One class of formulations is provided wherein the formulation is localized in the suprachoroidal space near the region into which it is administered. Another class of formulations is provided wherein the formulation can migrate to another region of the suprachoroidal space, thus allowing an injection in the anterior region of the eye in order to treat the posterior region. | 09-19-2013 |
20130245601 | INTRADERMAL DELIVERY OF SUBSTANCES - The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gauge needles, especially microneedles, placed in the intradermal space to deliver the substance to the intradermal space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient. Delivery devices which place the needle outlet at an appropriate depth in the intradermal space and control the volume and rate of fluid delivery provide accurate delivery of the substance to the desired location without leakage. | 09-19-2013 |
20130245602 | METHOD AND DEVICE FOR DELIVERING MEDICINE TO BONE - A method for the long-term delivery of fluids to a bone of a patient includes providing a cannulated bone screw and an insert configured to be coupled to the bone screw. The method further includes creating an aperture in the skin of a patient, inserting the bone screw into a bone of the patient through the aperture, and coupling the insert to the bone screw. The method further includes the steps of providing a fluid source, coupling the fluid source to the insert, and delivering a fluid from the fluid source to the insert. | 09-19-2013 |
20130245603 | Drug Eluting Balloons with Ability for Double Treatment - In embodiments, medical devices, such as balloon catheters, can deliver a biologically active material to body tissue of a patient. The medical device includes a sponge delivery layer which can deliver multiple doses of one or more therapeutic agents to the body tissue. The medical device can further include a drug reservoir, which can supply the delivery layer with one or more therapeutic agents. | 09-19-2013 |
20130245604 | Auto-Injector Device with a Medicated Module - Disclosed herein are various examples of a drug delivery system and corresponding method for delivering three or more medicaments. The system includes two major components: an auto-injector device that contains at least two medicaments and a medicated module that contains at least one medicament. The medicated module interfaces with the auto-injector device such that a combination dose comprising all of the medicaments can be delivered via a single dispense interface of the medicated module. In order to deliver a pre-defined combination dose, a user need only set the dose of one of the medicaments contained in the auto-injector device and need only activate the system once by actuating a dose delivery button on the auto-injector device. | 09-19-2013 |
20130253472 | MOTION ACTIVATED SEPTUM PUNCTURING DRUG DELIVERY DEVICE - A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum. | 09-26-2013 |
20130253473 | ORTHOPAEDIC SCREWS - An orthopaedic screw having a plurality of regions, at least one of which may be porous. The orthopaedic screw includes a head, a tip and at least one thread. The porosity of the screw of the present invention can vary within the part or region, including changes in pore shape, size and density. These characteristics can vary along the length of the screw axis and/or radially (from the outer diameter to the axis). The orthopaedic screw may further include at least one solid region formed of any implantable polymer, reinforced polymer or metal. | 09-26-2013 |
20130261596 | DRUG DELIVERY SYSTEM - A drug delivery device for delivering a drug pellet to a site beneath the skin of a patient is provided, the drug delivery device including a housing having a chamber configured to hold at least one drug pellet, the chamber having a loading end and a delivery end, the loading end of the chamber having an opening for receiving a plunger and a drug pellet and the delivery end having an opening for receiving the plunger and passage of the drug pellet. The housing includes at least one hole substantially perpendicular to the chamber and formed to at least partially intersect the chamber. A capture pin is provided configured to be receivable within the at least one hole. | 10-03-2013 |
20130261597 | Therapeutic Material Delivery System for Tissue Voids and Cannulated Implants - Described herein is a novel drug delivery assembly having particular applicability to the field of orthopedic and surgical medicine. The devices and assemblies described herein enable the efficient application and retention of potentially expensive therapeutic materials to very specific locations, particularly those associated with voids in bone and tissue. One particularly unique aspect of the present invention involves the introduction of constructs which promote the retention of therapeutic material in the target area of application for beneficial use, for example by forming a proximal barrier that prevents leakage of the therapeutic material out of the target area. Additionally, the present invention provides unique devices and methods for surgical introduction of such constructs. The present invention finds particular application in connection with introduction of stem and progenitor cells, bioactive molecules and bone scaffold materials in conjunction with bone voids and with the use of cannulated implants, such as bone screws (also surgical screws) and pins. The present invention also has beneficial use in the delivery of cancer drugs, antimicrobials, bone cements and other therapeutic materials. | 10-03-2013 |
20130261598 | IMPROVED METHOD OF TREATING PLEURAL EFFUSION - The present invention provides methods of treating pleural effusion in a subject, comprising removing fluid from the pleural space at an increased frequency, as compared to previous methods. | 10-03-2013 |
20130261599 | Dosing Unit With Safety Valve - A valve for an infusion pump device comprising a pump connection fluidly connected to a piston pump, an infusion site connection fluidly connected to an infusion set, and a reservoir connection fluidly connected to a reservoir is presented. The valve is in a first state (I) when the pump connection is fluidly connected to the infusion site connection and the reservoir connection is sealed closed and in a second state (II) when the pump connection is fluidly connected to the reservoir connection and the infusion site connection is sealed closed. The valve comprises one or more conduits, grooves, and/or recesses connected to environment and arranged so that no path exists within the valve between the infusion site connection and the reservoir connection that does not cross at least one of the conduits, grooves, and/or recesses, establishing a drain, independently if a path is closed during normal operation of the valve. | 10-03-2013 |
20130261600 | SURGICAL INSTRUMENT WITH DISTAL SUCTION CAPABILITY - A surgical instrument including a main unit and a suction conduit. The main unit includes at least one tubular body having a distal end, a proximal end, and an inlet disposed near the distal end. The suction conduit is slidably disposed over the main unit, and is slidably movable along the main unit between a retracted position, at which the suction conduit does not cover the inlet of the main unit, and an extended position at which the suction conduit covers the inlet of the main unit and a suction inlet of the suction conduit is placed in fluid-communication with the main unit inlet. The surgical instrument can be used as a suction tool by placing the suction conduit in the extended position and applying a vacuum through the inlet of the main unit and the suction inlet. | 10-03-2013 |
20130267931 | INJECTOR APPARATUS WITH FIXED PLUNGER AND METHOD OF USE - Disclosed herein is an injector device for delivering an implant, the device including a retracting element, a cannula needle, and a plunger. The device may comprise an latch that, when actuated by a user, causes the retracting element to move the cannula needle away from the delivery site, allowing the plunger to eject the implant into the site. The device may be configured for intraocular drug delivery. | 10-10-2013 |
20130267932 | Needle Assembly for the Delivery of at Least Two Medicaments - Various embodiments of needle assemblies for use with a drug delivery device to deliver two or more medicaments are provided. Additionally, various embodiments of methods for delivering two or medicaments are provided. In one embodiment, a needle assembly comprises an injection needle, a proximal housing member, a distal housing member, and a medicament transfer element. The proximal housing member contains a first medicament and is configured to attach to a drug delivery device containing a second medicament. The distal housing member is movably engaged with the proximal housing member such that relative axial movement between the proximal and distal housing members causes the first medicament to be delivered. Upon activation of the drug delivery device (e.g., activation of a dose button of the drug delivery device) the second medicament is transferred, via the medicament transfer feature, from the drug delivery device to the injection needle of the needle assembly such that the second medicament can be delivered. | 10-10-2013 |
20130274706 | MEDICAL INJECTOR WITH POST-AUTORECONSTITUTION DOSE SETTING AND AUTOPLUNGER DRIVE - A medical injector is provided herein having a body; a reservoir containing first and second mixable components; a stopper; a plunger disposed in the body; a spring disposed to advance the plunger; a first releasable retainer for releasably retaining the plunger in a first state against force of the spring; a first trigger for causing the first releasable retainer to release the plunger; a second releasable retainer for releasably retaining the plunger in a second state against force of the spring; and, a second trigger for causing the second releasable retainer to release the plunger. The spring causes the plunger to advance so that the stopper traverses at least a predetermined extent of advancement thereby causing mixing of the first and second mixable components. Advantageously, with the subject invention, a medical injector is provided which allows for autoreconstitution with subsequent dose setting and autoplunger activation being activated by separate triggers. | 10-17-2013 |
20130274707 | Three-Chambered Autoinjector - The present invention relates to a three-chambered autoinjector as well as to the methods of administering medicaments to a human using the three-chambered autoinjector. In certain embodiments, the autoinjector includes a first medicament in liquid form, a second medicament preferably in solid form, and a liquid composition for diluting the second medicament, and utilizes a three-chambered design so as to administer the first medicament and a solution comprising the second medicament and the liquid composition at different injection depths into the body of a human. In an alternative embodiment an autoinjector is provided that delivers medicaments at the same injection depth. | 10-17-2013 |
20130281970 | SAFETY SYRINGE AND NEEDLE SHIELD - The disclosure pertains to a safety syringe having a retractable needle shield which is capable of being retracted to expose the needle for use; being advanced to a needle shielding position; and, if desired, of being removed from the syringe with the shielded needle safely contained within the retractable needle shield via a frangible segment between the syringe barrel and the needle/needle shield components. The disclosure further pertains to a method of using the safety syringe having a retractable needle shield. | 10-24-2013 |
20130281971 | CATHETER ALLOWING VARIABLE DOSING OF AN ACTIVE AGENT - A drug eluting catheter includes an active agent, such as a drug or chemical substance, which is integrated with the catheter and allows variable dosing of the agent for elution to the patient's body. The catheter includes a dosing region and graduated markings or is associated with a measurement device that includes graduated markings that correspond to a range of dose of the active agent associated with the catheter. By removing or masking an undesired dosing region prior to administration, a user may vary the dosage to suit a patient's needs. | 10-24-2013 |
20130281972 | PASSIVELY SHIELDING NEEDLE ASSEMBLY WITH SKIN SENSOR - A shielding needle assembly is provided with a hub having a needle cannula with a puncture tip extending from a forward end thereof, and a shield member in telescoping association with the hub. A drive member biases the hub and the shield member away from each other for relative telescopic movement between a first position in which the puncture tip extends from a forward end of the shield member, and a second position in which the puncture tip is encompassed within the shield member. A pivoting lever maintains the hub and the shield member in the first position against the bias of the drive member with the needle cannula exposed for use. The lever is pivotable during contact with a patient's skin surface such as during venipuncture, thereby releasing the hub and the shield member from the first position and permitting the drive member to bias the hub and the shield member toward the second position. | 10-24-2013 |
20130281973 | DEVICES AND METHODS FOR ANTERIOR ARYTENOID ADDUCTION - Provided herein are devices and methods for anterior arytenoid adduction. The device may comprise a wire having a first end and a second end at opposite ends of a longitudinal axis, the wire forming a spiral along the longitudinal axis and having a double hook at the first end, a suture threaded through the spiral of the wire from the second end to the first end, the suture forming a turn at the first end and passing exterior to the spiral to the second end. The method may comprise advancing a suture and hook from the subject's anterior thyroid cartilage or cricothyroid membrane to the muscular process of the subject's arytenoid, attaching the hook to the muscular process, and applying tension to the suture to rotate the muscular process and adduct the arytenoid. | 10-24-2013 |
20130281974 | PUMP ASSEMBLY WITH SWITCH - A wearable infusion pump assembly includes a reusable housing assembly, and a disposable housing assembly including a reservoir for receiving an infusible fluid. The wearable infusion pump assembly also includes a releasable engagement assembly configured to allow the reusable housing assembly to releasably engage the disposable housing assembly. A switch assembly of the wearable infusion pump assembly is configured to effectuate a functionality of the infusion pump assembly. | 10-24-2013 |
20130281975 | METHOD FOR VECTOR DELIVERY - Provided is a lentiviral vector for delivery to the brain for use in treating a neurological condition, wherein the lentiviral vector is delivered directly to the brain by delivering the lentiviral vector via six or fewer tracts per hemisphere, at a single deposit point per tract. | 10-24-2013 |
20130281976 | CANNULA SYSTEM - The present disclosure provides a cannula useful for introducing a thermally responsive polymer in situ. In embodiments, the cannula possesses more than one cannula, with the thermally responsive polymer introduced in one cannula, and a material such as a coolant in a second cannula which prevents premature gelling of the thermally responsive polymer. | 10-24-2013 |
20130281977 | DEVICE FOR CONTROLLED RELEASE OF A BIOACTIVE AGENT - Present invention relates to a device for controlled release of a bioactive agent. The device comprises a thin film located on the surface of the device, wherein said thin film comprises a bioactive agent-containing layer comprising a polymeric matrix and at least one bioactive agent. | 10-24-2013 |
20130289523 | DEVICE, KIT AND METHOD FOR PLACING JEJUNAL TUBE DEVICE THROUGH STOMACH AND INTO SMALL INTESTINE - A device and method for placing jejunal tube device through stomach and into small intestine with spring mechanism that is curled to diameter that is similar small bowel diameter, wherein the spring mechanism can be straightened during placement with a stiffening apparatus. The stiffening apparatus is guided by a forceps, and includes a retractable wire for use in attachment to the forceps. A c-plug is provided for centering jejunal tube during the placement procedure and to facilitate insufflation, the c-plug being split about midline to facilitate removal of the c-plug after tube placement. | 10-31-2013 |
20130289524 | Passively Shielding Needle Device - A shieldable needle device includes a hub with and a needle cannula having a puncture tip extending from a forward end thereof, and a shield member in telescoping association with the hub. At least one of the hub and the shield member are adapted for relative axial movement with respect to the other between a first position in which the puncture tip of the needle cannula is exposed from a forward end of the shield member and a second position in which the puncture tip of the needle cannula is encompassed within the shield member. A drive member extends between the hub and the shield member, biasing the hub and the shield member axially away from each other. A packaging cover may further extend about the needle cannula, applying external pressure between the cooperating portions of the hub and the shield. | 10-31-2013 |
20130289525 | Auto-Injector - The invention refers to an auto-injector for administering a dose of a liquid medicament, comprising: | 10-31-2013 |
20130296824 | MICRONEEDLE BASED TRANSDERMAL DRUG DELIVERY DEVICE AND METHOD - A minimal pain microneedle based transdermal drug delivery device and method. The device has a clamshell configuration, where the top part of the clamshell holds one or more chambers configured to store liquid drugs, and also configured to store one or more spring operated plungers, and at least one microneedle. The top portion of the device is attached to the bottom portion of the device by a combination hinge and a moveable shutter mechanism. In its shut position, the shutter mechanism prevents the plungers from moving, and the open shutter position releases the plunger. When the user applies the bottom of the device to the user's skin and presses on the top portion with enough force to overcome a detent mechanism, the top portion pivots against the bottom portion forcing the microneedle through an aperture and into the skin painlessly. Pressing on the shutter mechanism then results in drug self-administration. | 11-07-2013 |
20130296825 | INTRAOCULAR DELIVERY DEVICES AND METHODS THEREFOR - Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described. | 11-07-2013 |
20130296826 | SAFETY CATHETER - A device and method for positioning a catheter to establish a fluid access site into the vasculature of a patient includes a luer assembly having a cannula or catheter, a shuttle assembly having a stylet for stiffening the catheter, and a holder assembly having an actuator for providing controlled retraction into a handle. The safety catheter comprises a flash window that allows a clinician to view when the vasculature of a patient has been properly accessed and to confirm that the stylet has been fully retracted into a safe position. | 11-07-2013 |
20130296827 | DEVICES AND METHODS FOR PROTECTING A USER FROM A SHARP TIP OF A MEDICAL NEEDLE - There are disclosed devices and methods for protecting a user from a sharp tip of a medical needle. In an embodiment, a device includes a central body portion, a medical needle having a sharp tip, a pair of wings in attachment to the central body portion, and a mechanical fastener disposed on at least one of the wings, the mechanical fastener configured to selectively attach the wings together with the medical needle positioned between the wings so as to protect a user from the sharp tip of the medical needle. In another embodiment, a method includes withdrawing a sharp tip of a medical needle from a patient, closing a pair of wings with the medical needle positioned between the wings, and fastening the wings together with the medical needle positioned between the wings so as to protect a user from the sharp tip of the medical needle. | 11-07-2013 |
20130296828 | THERAPEUTIC MATERIAL DELIVERY SYSTEM FOR TISSUE VOIDS AND CANNULATED IMPLANTS - Described herein is a novel drug delivery assembly having particular applicability to the field of orthopedic and surgical medicine. The devices and assemblies described herein enable the efficient application and retention of potentially expensive therapeutic materials to very specific locations, particularly those associated with voids in bone and tissue. One particularly unique aspect of the present invention involves the introduction of constructs which promote the retention of therapeutic material in the target area of application for beneficial use, for example by forming a proximal barrier that prevents leakage of the therapeutic material out of the target area. Additionally, the present invention provides unique devices and methods for surgical introduction of such constructs. The present invention finds particular application in connection with introduction of stem and progenitor cells, bioactive molecules and bone scaffold materials in conjunction with bone voids and with the use of cannulated implants, such as bone screws (also surgical screws) and pins. The present invention also has beneficial use in the delivery of cancer drugs, antimicrobials, bone cements and other therapeutic materials. | 11-07-2013 |
20130296829 | NON-SEDATING ANTIHISTAMINE INJECTION FORMULATIONS AND METHODS OF USE THEREOF - Described herein are automatic injectors suitable for administration of a non-sedating antihistamine, and methods of using the automatic injectors. A specific non-sedating antihistamine is cetirizine. The automatic injectors are useful in treating acute urticaria or angioedema associated with an acute allergic reaction including anaphylaxis. | 11-07-2013 |
20130304020 | BLOOD TREATMENT SYSTEMS AND METHODS - Dialysis systems comprising actuators that cooperate to perform dialysis functions and sensors that cooperate to monitor dialysis functions are disclosed. According to one aspect, such a hemodialysis system comprises a user interface model layer, a therapy layer, below the user interface model layer, and a machine layer below the therapy layer. The user interface model layer is configured to manage the state of a graphical user interface and receive inputs from a graphical user interface. The therapy layer is configured to run state machines that generate therapy commands based at least in part on the inputs from the graphical user interface. The machine layer is configured to provide commands for the actuators based on the therapy commands. | 11-14-2013 |
20130304021 | DISENGAGEMENT RESISTANT TELESCOPING ASSEMBLY AND UNIDIRECTIONAL METHOD OF ASSEMBLY FOR SUCH - Extension rods of a telescoping assembly (TSA) may be assembled in a single direction. The rods may optionally be threaded together from a reverse extended configuration. The rods may optionally resist disattachement during extension. The inner rod may optionally included a leading fastener and/or the outer rod may optionally include a rear fastener. Each rod may optionally be molded as a single piece. End caps may optionally be added to the TSA after extension of the rods. An end cap may optionally include a rotation stopper. In some embodiments the TSA may include a supporting shoulder. | 11-14-2013 |
20130304022 | CATHETER WITH DIRECTION ORIENTATION - A regional anesthesia catheter used with a guide, for example a cannula, has a distal portion integrally connected to its main portion by a junction portion that has a cross-sectional profile different from the distal and main portions, so as to predispose the distal portion of the catheter to move in a given direction when it is not constrained by the guide. The cross-sectional profile of the junction portion may be configured in a particular shape, or be constructed to have a flexibility that predisposes the distal portion to bend, curve or move toward a given direction. A number of portions of a catheter may be configured to bend at a predefined direction. Further, a catheter may be configured to have a cross sectional profile or a predefined flexibility along its entire length to cause the catheter to move in a predefined direction. | 11-14-2013 |
20130304023 | Fabric Medical Device Having a Tapered Transition and Method of Making - A fabric medical device and method of making the device can include warp yarns and fill yarns woven together to form a first tubular extent having a first diameter, a second tubular extent having a second diameter, and a transition tubular extent having a graduated diameter between the first and second tubular extents. A tapered edge can be formed along the transition tubular extent by weaving such that a graduated number of warp yarns are disengaged along the transition tubular extent. A seam can be woven along the tapered edge that is configured to provide a substantially fluid-tight transition between the first and second tubular extents. The device can further include the warp yarns in at least the transition tubular extent having a tenacity higher than the tenacity of the fill yarns. The device can be a bone filler delivery device adapted to deliver bone filler in an internal body region. | 11-14-2013 |
20130304024 | PEN-TYPE INJECTOR - The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same. | 11-14-2013 |
20130304025 | SAFE NEEDLE METHODS, APPARATUS, AND SYSTEMS - A bandage can be used to secure a needle to an access site so as to prevent unintended movement or withdrawal of the needle from the access site during administration of a treatment to a patient. After treatment, the needle can be removed by manipulating a portion of the bandage. Another portion of the bandage can be maintained in position over the access site during needle removal and can be used to promote clotting of the site after needle removal. The bandage may include a clotting agent, a hemostasis pad, and/or a clot-promoting structure. Additionally or alternatively, finger pressure can be applied to the access site through the bandage. For example, the bandage may include a viewing window without any adhesive to allow visual monitoring of the access site during treatment. Finger pressure may be applied to the viewing window and thereby to the access site during and after needle removal to encourage hemostasis. | 11-14-2013 |
20130304026 | FLUSH ENTRANCE HEMOSTASIS VALVE WITH UNOBSTRUCTED PASSAGEWAY - A method of placing a catheter into a patient while preventing disadvantageous escape of fluid from the patient comprises providing a catheter secured to a valve hosing. The catheter has a proximal end, a distal end and an interior lumen. The valve housing has a first port, a second port, and a fluid path running between the first and second ports. The catheter and the valve housing have a hollow needle extending therethrough. The method further comprises piercing the patient's skin, thereby inserting the catheter into the patient. The method further comprises holding the catheter and valve housing in place while removing the hollow needle through the catheter and valve housing. The hollow needle passes through the first and second ports of the valve housing. | 11-14-2013 |
20130310801 | SYSTEMS, DEVICES AND METHODS FOR FLUID/DRUG DELIVERY - Fluid delivery systems, methods and devices for delivering a therapeutic fluid to the body of the patient are disclosed. A fluid delivery device for delivering fluid to the body of the patient includes a housing having an upper wall, a lower wall, and an opening. The device includes a well-arrangement mechanism disposed inside the housing. The well-arrangement mechanism includes a tubular member having a bore disposed between the wall openings. The device also includes a penetrating cartridge for delivery of therapeutic fluid to the body of the patient. The cartridge is configured to engage the bore following its insertion through the opening such that the therapeutic fluid can be delivered through the tubular member into the penetrating cartridge, and into the body of the patient, when the penetrating cartridge engages the bore. | 11-21-2013 |
20130310802 | Portable Insulated Carrier Containing Prepared Doses of Medications - Provided herein is a portable insulated carrier for maintaining a syringe at an acceptable temperature for an extended period of time. The portable insulated carrier includes: a container having a front, a back, an open top, and defining an interior cavity; a closure for covering the open top of the container; at least one syringe holder in the interior cavity of the container, which is configured to receive and retain the syringe in an upright position; and an insulating member positioned in the insulating pocket, the insulating member being configured to prevent body heat of a user from being transferred to the syringe in the at least one syringe holder. The carrier is configured to maintain the syringe at a temperature of below 25 degrees Celsius for at least one hour. | 11-21-2013 |
20130317476 | COLLAPSE-RESISTANT SWELLABLE CATHETER - A catheter and method of making it are disclosed. The catheter includes a swellable inner element and a non-swellable outer sleeve covering an outer wall of the inner element. The inner element absorbs liquid from infusate administered through the catheter and swells in size. Outward swelling of the inner element is restrained by the non-swellable outer sleeve. The inventive catheter can be substituted for a conventional catheter that is used in an insulin infusion system. | 11-28-2013 |
20130317477 | DEVICES AND METHODS FOR DELIVERING MEDICAMENTS FROM A MULTI-CHAMBER CONTAINER - An apparatus includes a medicament container, a first elastomeric member, a second elastomeric member and a stopper. The first and second elastomeric members are disposed within the medicament container. The first elastomeric member, a first portion of the medicament container and the second elastomeric member collectively define a medicament volume. The stopper is coupled to a distal end portion of the medicament container. The second elastomeric member, a second portion of the medicament container and the stopper collectively define a vent volume. A first retainer of the stopper is configured to engage a first portion of a carrier to limit movement of the medicament container when in a first position. A second retainer of the stopper is configured to engage a second portion of the carrier to limit movement of the medicament container when in a second position. | 11-28-2013 |
20130317478 | VISCOUS FLUID INJECTOR - A self-contained apparatus and corresponding methods are provided for delivering viscous fluids in a controlled manner, such as delivering a viscous fluid in a surgical setting. The self-contained apparatus can include a motion following pressure regulator that allows for linear control of a regulated pressure. The regulated pressure can be used for dispensing a viscous fluid from a syringe that is coupled to the self-contained apparatus. The pressure regulator regulates a pressure derived from a pressurized fluid reservoir located at least partially within a housing of the apparatus. This allows the viscous fluid to be delivered using pressure to provide a driving force greater than a force easily delivered manually, while still allowing a surgeon to retain fine control over the rate of viscous fluid delivery. | 11-28-2013 |
20130317479 | AUTO-INJECTOR - An auto-injector for administering a dose of a liquid medicament is presented that has a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. There is also a trigger button arranged distally or laterally in or on the case, a control spring arranged around the carrier, and a needle extension control mechanism for coupling a proximal end of the control spring to either the carrier for advancing it for needle extension or to the chassis for needle retraction depending on the relative axial position of the carrier and the chassis. | 11-28-2013 |
20130317480 | DRIVE ASSEMBLY FOR AN AUTOINJECTOR AND A METHOD OF ASSEMBLING AN AUTOINJECTOR - The invention provides a drive mechanism for an autoinjector, configured to be coupled to a drug containing portion to form a complete autoinjector, the drive mechanism comprising: a housing ( | 11-28-2013 |
20130324965 | Preservative-Free Follicle Stimulating Hormone Solution Delivery Device - A one-time use device to deliver preservative-free follicle stimulating hormone (FSH) solution is disclosed. The device includes a needle covered by a sliding needle shield, which covers the needle in all modes of the device. The device can be placed into a ready-to-use position in four or fewer user steps. The device has a knob for setting a desired dose of FSH. The knob includes longitudinally spaced elements respectively corresponding to the lock position and the seven or fewer discrete dosing positions. The device locks after one use and cannot be reused thereafter. | 12-05-2013 |
20130324966 | DEVICE FOR HARVESTING, PROCESSING, AND TRANSFERRING ADIPOSE TISSUE - The present disclosure provides devices and methods for harvesting and processing tissue from patients for grafting. The devices can include a tissue collection chamber for ascetically collecting, processing, and/or re-implanting adipose tissue. | 12-05-2013 |
20130324967 | TRANSVASCULAR ACCESS DEVICE AND METHOD - Transvascular access devices and methods for transvascular access are provided. The transvascular access devices can include a guidewire lumen and a guide tube and stylet disposed in a second lumen. The guide tube can be used to control the orientation of the stylet and provide additional support for the stylet. The methods include providing a second entry point in a vessel of a patient remote from a first entry point. A vascular catheter can enter the vascular system of a patient at a first entry point and be advanced to a second entry point. A guide tube can be advanced out the second lumen of the vascular catheter with a stylet advanced out of the guide tube to pierce the vessel wall and skin of the patient at the second entry point. A catheter can be introduced to the vascular system at the second entry point. | 12-05-2013 |
20130331817 | FLUSHING MEDICAL DEVICES - Syringes and flushing medical devices are generally discussed herein for withdrawing, injecting, or instilling fluids. More particularly, syringe tips and flushing tip adaptors with multiple flow channels are discussed for flushing vascular access devices. The tips have cut-outs that are located and sized to produce a relatively wider flow profile than a typical syringe tip with a single central lumen to facilitate flushing the vascular access devices. | 12-12-2013 |
20130331818 | DRUG RELEASING PELVIC TREATMENT SYSTEM AND METHOD - Various embodiments of a pelvic treatment system and method are provided. The present invention can include one or more drug eluting darts or barbs that are lodged into the wall and will elute the drug over a desired time period (weeks, months for example) to treat OAB, BPH, tissue weaknesses, or other disorders or diseases. | 12-12-2013 |
20130338631 | Disposable Syringe Applicators for Multi-Component Formulations, and Methods of Use Thereof - Aspects of the invention relate to an applicator which can house multiple components of a formulation in separate receptacles. In certain embodiments, an applicator of the invention can be used for, but is not limited to, applying hydrogel formulations to dura mater, abdominal tissue in hernia repair, tissues near the spine, lung tissue, intestinal tissue, or any of the internal tissues. | 12-19-2013 |
20130338632 | SILK FIBROIN-BASED MICRONEEDLES AND METHODS OF MAKING THE SAME - A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery. | 12-19-2013 |
20130338633 | Methods And Compositions For Treating Post-Cardial Infarction Damage - Methods and compositions for treating post-myocardial infarction damage are herein disclosed. In some embodiments, a carrier with a treatment agent may be fabricated. The carrier can be formulated from a bioerodable, sustained-release substance. The resultant loaded carrier may then be suspended in at least one component of a two-component matrix system for simultaneous delivery to a post-myocardial infarction treatment area. | 12-19-2013 |
20130338634 | Methods And Compositions For Treating Post-Cardial Infarction Damage - Methods and compositions for treating post-myocardial infarction damage are herein disclosed. In some embodiments, a carrier with a treatment agent may be fabricated. The carrier can be formulated from a bioerodable, sustained-release substance. The resultant loaded carrier may then be suspended in at least one component of a two-component matrix system for simultaneous delivery to a post-myocardial infarction treatment area. | 12-19-2013 |
20130338635 | PRESSURE INDEPENDENT DELIVERY METHOD FOR PORTABLE INFUSION PUMP - Described is method for maintaining proper drug delivery rate by monitoring atmospheric effects on a drug infusion device. The device may include one or more vents that permit the passage of gas between the exterior and interior of the device's housing. The device may also include one or more pressure and/or temperature sensors, the readings from which may be used to determine malfunctions in the venting of the device and/or changes in pressure that could cause the unintended over-delivery or under-delivery of medication. | 12-19-2013 |
20130338636 | MATERIALS AND METHODS FOR FILLING BIOLOGICAL CAVITIES AND PREVENTING LEAKAGE OF INJECTED THERAPEUTIC AGENTS - The subject invention pertains to medical apparatuses and methods for reducing or preventing leakage of injected therapeutic agents (including liquid-containing substances, cells) into a solid or hollow tissue/organ after puncturing. | 12-19-2013 |
20130345665 | CATHETER SYSTEM - An infusion catheter system comprises a surgical needle and an infusion catheter. The infusion catheter has an internal bore; and the needle has a protrusion extending from its proximal end. The protrusion is adapted to mate with the internal bore of the infusion catheter. Through this innovative connection method, the needle can take the same diameter as the catheter. Therefore the puncture marks caused in the patient will have a smaller diameter than with conventional “introducer needles”, reducing pain, leakage and the chances of infection. Furthermore, the catheter may be introduced subcutaneously, further reducing the risk of infection by eliminating the risk of skin bacteria being drawn into the wound cavity. | 12-26-2013 |
20130345666 | User Interface for Delivery System Providing Dual Setting of Parameters - The invention provides a user input device for operating a drug delivery system is provided, comprising display means adapted to simultaneously display at least two user controllable settings, and user input means allowing a user to simultaneously and directly set each of the simultaneously displayed user controllable settings. By this arrangement a user can effectively and safely enter related information without having to jump between two or more input screens. | 12-26-2013 |
20130345667 | BONE TAMP APPARATUS AND METHOD - A tamping apparatus is described that includes a cannula that has a tubular wall that includes a distal end portion that defines a tamping face. The cannula defines a longitudinally aligned aperture or lumen that provides access for an insert and the injection of treatment materials such as a bone graft. The distal end portion of the cannula can also include a plurality of movable elements that can be a part of or connected to the tubular wall. The tamp apparatus can also include a cannula or stylet that can be moved within aperture of cannula to move elements between the first position and second position of tamp apparatus. | 12-26-2013 |
20130345668 | SKIN SECURABLE INFUSION ASSEMBLY AND METHOD OF USE - A skin securable infusion assembly includes a housing having a skin contacting adhesive layer and supporting an infusion cannula. An elongate tubular reservoir having a plunger slidably disposed therein is configured to contain a supply of liquid medication between a distal opening of the reservoir and the plunger. The reservoir has an assembled configuration in which the reservoir is supported on the housing. An actuation mechanism is coupled with the plunger and, when the reservoir is in the assembled configuration, an actuation of the actuation mechanism moves the plunger toward the distal opening and forces a portion of the liquid medication through the distal opening and into the infusion cannula. | 12-26-2013 |
20130345669 | Clip Syringe - A single use pre-filled delivery device is disclosed having a deformable container including a side wall having an inside surface defining a chamber for retaining fluid, a clip element, and a locking element. The deformable container further includes a closed proximal end and an open distal end including a male luer tip having a passageway therethrough providing fluid communication with the chamber. The male luer tip may be removably connectable to a female luer connection of a vascular access device. The clip element includes a distal end, proximal end, and a pivot located between the distal end and the proximal end of the clip element for collapsing the deformable container to drive fluid out of the chamber by movement of the proximal end towards the distal end. The pivot may be a hinge, which may be in the form of a living hinge. The deformable container may be attached to the clip element. The locking element may be disposed on the clip element. A method of administering a fluid to a vascular access device using a single use pre-filled delivery device as described herein is also disclosed. | 12-26-2013 |
20130345670 | DEVICES AND METHODS FOR THE TREATMENT OF TISSUE - Systems, methods and devices for the treatment of tissue are disclosed. A system includes an elongate tube with a distal portion. A treatment element is positioned on the elongate tube distal portion, the treatment element constructed and arranged to treat target tissue. In one embodiment, gastrointestinal tissue is modified for the treatment of diabetes. | 12-26-2013 |
20130345671 | MICRONEEDLE-CONTAINING DRUG DELIVERY DEVICE TO BE ATTACHED TO EXTERIOR WALL OF VASCULAR VESSEL AND METHOD FOR DRUG DELIVERY THEREWITH - A drug delivery device, which is to be attached to the exterior wall of a vascular vessel, includes: a) a biocompatible device body for surrounding a vascular vessel; b) one or plurality of biocompatible microneedle, which are connected to the interior of the biocompatible device body and capable of penetrating up to the tunica media so as to deliver drug to the vascular smooth muscle cells. The drug delivery device and method enable spatial and temporal control of the drug ejected onto the blood cells and enable insertions of two or more different drugs at different delivery speeds and durations, thereby significantly improving the treatment success rate. | 12-26-2013 |
20140005634 | ASPIRATION APPARATUS AND METHODS | 01-02-2014 |
20140005635 | Bone Cement System For Bone Augmentation | 01-02-2014 |
20140012226 | DRUG INFUSION WITH PRESSURE SENSING AND NON-CONTINUOUS FLOW FOR IDENTIFICATION OF AND INJECTION INTO FLUID-FILLED ANATOMIC SPACES - An automatic injection apparatus uses non-continuous fluid-flow of drugs to identify an intended injection site and includes a drive mechanism, a sensor and a controller for establishing fluid flow and pressure and preventing fluid flow until the pressure drops below a predetermined threshold. The pressure threshold is determined based on an internal pressure generated during an injection and more fluid will not flow until it drops below a predetermined pressure. An injection is performed to establish an initial pressure threshhold and then to stop the fluid flow into a patient until the pressure drops below a predetermined pressure which allows fluid flow to resume, thus identifying a fluid filled tissue space. The initial pressure threshold is used as a control parameter to a microprocessor below which controls the rate of injection. Fluid flows below certain pressures are also used to identify a specific location within the body during injections. | 01-09-2014 |
20140012227 | SYRINGE - The present invention relates to a syringe, particularly to a small volume syringe such as a syringe suitable for ophthalmic injections. | 01-09-2014 |
20140012228 | METHODS, DEVICES AND SYSTEMS FOR ACCESSING A HOLLOW ORGAN - The methods, devices and systems described herein relate to accessing a hollow organ with increased accuracy and safety. In one example, they relate to transseptal crossings of the atrial septal wall, preferably from the right atrium into the left atrium. Numerous different devices are described for performing access methods, each of which can be used with a piercing stylet that transitions to an atraumatic configuration after piercing the intervening tissue. | 01-09-2014 |
20140012229 | DRIVE CONTROL MECHANISMS AND AUTOMATIC INJECTORS FOR INJECTABLE CARTRIDGES - An automatic injector includes a housing having a guide, a drive control mechanism, a transmission assembly, a motor, and an energy source. The housing may further include a cartridge cover. A drive control mechanism includes a drive screw, a cartridge carrier, a plunger carrier, and one or more control transfer instruments, such as a puck or cylinder. The drive screw interfaces and connects with the plunger carrier. The automatic injector is configured to accept a variety of syringes as cartridges for drug delivery. The cartridges may be ejected from the injector and safely disposed after use, making the injector a reusable automatic injector. The reusable automatic injector may further include one or more sensors, such as a cartridge sensor and a patient sensor. The novel incorporation of the drive control mechanisms into the automatic injectors of the present invention enables a single motor and transmission assembly to drive the function of multiple components, which may include the steps of: preparation and alignment of a cartridge for injection, removal of a safety cap or needle shield, needle injection, drug dose delivery, and syringe and/or needle retraction. Methods of manufacture and methods of use are also disclosed. | 01-09-2014 |
20140012230 | METHOD AND APPARATUS FOR TREATMENT OF CARDIAC DISORDERS - The present invention is directed to systems and methods for delivering therapy for a cardiac disorder, wherein the system comprises a source for supplying a protein formulation containing a protein that is otherwise deficient in cardiac cells in a patient with a cardiac disorder, and a catheter having a proximal end and a distal end for delivering the protein formulation to the pericardial sac region of a human heart. | 01-09-2014 |
20140018769 | MOBILE TRACKING AND SUBDUING APPARATUS, METHOD, AND COMPUTER PROGRAM PRODUCT - A mobile tracking and subduing apparatus of a target object that includes liquid storage tank that is configured hold a predetermined amount of a liquid, a probe configured to inject the liquid from the liquid storage tank into a skin surface of a target object, an optical detection unit for obtaining image or video data, a GPS unit that generates positional data, a wireless communications interface configured to receive command data, and a target tracking unit for detecting and tracking the target object based on the received positional data, command data, and images or video data and inject the contents of the liquid storage section into the target object via the probe. | 01-16-2014 |
20140018770 | HANDHELD MEDICAL SUBSTANCE DISPENSING SYSTEM, APPARATUS AND METHODS - Various handheld medical dispensing configurations and methods including the following. Handheld medical dispensing system comprises a syringe, which has a plunger, releasably mounted to syringe actuation apparatus, the apparatus having an actuator configured such that it can move the plunger more than once to dispense a plurality of amounts of substance from the syringe. A method of dispensing fluid from a syringe comprises holding a medical substance delivery system including a syringe, which has a needle, and which is secured to syringe actuation apparatus configured to dispense predetermined amounts of the substance from the syringe, penetrating the needle at one patient site and using the apparatus to deliver a predetermined amount of the substance, and penetrating the needle at another patient site and using the apparatus to deliver a predetermined amount of the substance. | 01-16-2014 |
20140018771 | MINIATURE IMPLANTED DRUG DELIVERY DEVICES AND INSERTER SYSTEMS FOR INTRODUCING SUCH DEVICES | 01-16-2014 |
20140025035 | MULTI-LUMEN BIOLOGIC-DELIVERING DEVICE - Arrangements and methods for delivering bioactive agents and/or cells into an extended volume of tissue are disclosed. In one embodiment, a cell-delivering needle arrangement has a tube positioned within a tube and fixedly attached to a wall thereof. In one exemplary method, a cell-delivering needle is advanced into tissue, a suspension of cells is passed through a first lumen and out of side ports, and a suspension of cells is passed through a second lumen and out of a distal opening. Other embodiments are disclosed. | 01-23-2014 |
20140025036 | ACCESS DEVICE - An access device for placing a medical article within a body space includes a needle, a dilator, and a sheath. The needle can include an elongated needle body and a hub from which the needle body extends. The dilator can be slideably disposed on the needle body and include a dilator hub and an elongated dilator shaft that extends from the dilator hub. The sheath can include a tubular sheath body, and a sheath hub. The tubular body can be disposed on the dilator. The needle, dilator, and sheath can be held together by a disposable bracket engaged with the needle and the sheath. | 01-23-2014 |
20140031788 | RIGID REINFORCING EXOSKELETAL SLEEVE FOR DELIVERY OF FLOWABLE BIOCOMPATIBLE MATERIALS - Exoskeletal devices or sleeves that can be used with the delivery tube of an applicator device to help dispense fluids, typically flowable biocompatible materials such as hemostatic agents, adhesives, or sealants, onto specific sites in the human body for a medical reason are disclosed. | 01-30-2014 |
20140031789 | DEVICES, SYSTEMS AND METHODS FOR MEDICAMENT DELIVERY - An apparatus includes a movable member and a valve coupled to the movable member. The movable member is configured to be disposed within a housing of a medical device and has a first end portion and second end portion. A portion of the first end portion is configured to define a portion of a boundary of a gas chamber. The first end portion defines an opening configured to be in fluid communication between the gas chamber and an area outside the gas chamber. The second end portion is configured to be coupled to a needle configured to deliver a medicament into a body. The valve is configured to selectively allow fluid communication between the gas chamber and the area outside the gas chamber through the opening defined by the first end portion of the movable member. | 01-30-2014 |
20140031790 | POULTRY INJECTION APPARATUS AND METHODS - Injection apparatus and methods of positioning an injection needle in an injection apparatus are described herein. The injection apparatus may include one or more axes of rotation. The injection apparatus may include an injection unit attached to a support assembly that moves between a rearward position and a forward position, with the injection unit attached to the support such that it rotates relative to the support assembly about an injection unit axis. | 01-30-2014 |
20140031791 | BONE SCREWS AND METHODS OF USE THEREOF - The invention features bone screws having a threaded screw body and a screw head attached to one end of the screw body, the bone screw further including: a) an interior channel extending longitudinally through the screw head and through at least a portion of the screw body, wherein the interior channel has a width of less than 5.0 millimeters; and b) a plurality of radially-disposed delivery channels connecting the interior channel to the exterior of the screw body, each delivery channel having exterior openings. The invention further features devices that include a bone screw and a delivery manifold detachably attached to the screw head of the bone screw. In addition, the invention features methods of treating a patient having a bone defect by using a bone screw described herein. | 01-30-2014 |
20140039451 | DEVICES AND METHODS FOR WEARABLE INJECTION GUIDES - Wearable injection guides and manufacture and use thereof are described, which include: a rigid material formed to substantially conform in shape to a topography of a body region of an individual, the rigid material substantially impenetrable to an injection needle, and the rigid material including one or more injection needle access regions arranged in a treatment pattern. | 02-06-2014 |
20140039452 | DEVICES AND METHODS FOR WEARABLE INJECTION GUIDES - Wearable injection guides and manufacture and use thereof are described, which include: a rigid needle-penetrable material having an inner surface and an outer surface, the inner surface having form-fitting contours substantially conforming to a topography of a body region of an individual and the outer surface including one or more fiducials indication of at least one treatment parameter. | 02-06-2014 |
20140039453 | Subcutaneous Infusion Set With Side Port Fluid Connector - An infusion set preferably for use with an inserter is disclosed. The infusion set includes a septum cap that encapsulates an upper resilient septum and a lower resilient septum of a base, and includes at least one radial port to receive insertion of a blunt cannula when an extension set hub is engaged with the infusion set in a direction substantially parallel to the skin surface. The extension set hub is configured to provide a snap-fit engagement with the septum cap, wherein the blunt cannula of the extension set hub is guided through the radial port of the septum cap and penetrates the interface between the upper septum and the lower septum. The extension set hub and the septum cap can be rotated in a 360 degree manner about the base of the infusion set. | 02-06-2014 |
20140039454 | METHODS OF TREATING SUBCHONDRAL BONE TO PREVENT THE PROGRESSION OF OSTEOARTHRITIS IN JOINTS - Methods of therapeutically treating osteoarthritis in a joint are disclosed. These methods aim to prevent the progression of osteoarthritis of a joint by treating the subchondral bone to heal, or delay the onset or progression of, bone marrow edema or lesions in the subchondral bone region of the joint. Associated devices and instruments for such subchondral treatment are also provided. | 02-06-2014 |
20140039455 | User Profile Backup System For an Infusion Pump Device - Some embodiments of an infusion pump system can include a controller device that communicates with a pump device, the pump device having a memory device. The controller device can be configured to record controller-related data, such as user profile data on the memory device of the pump device. This user profile data that is stored in the memory of the pump device can serves as a data backup system that permits the user to program a new controller device in a situation where the original controller device is lost or damaged. In addition or in the alternative, the controller device can be configured to receive controller-related data, such as software update programs or backup controller data, from the memory device of the pump device. | 02-06-2014 |
20140039456 | INTRAOCULAR DELIVERY DEVICES AND METHODS THEREFOR - Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on the injector device, or on a portion of the injection device housing, or on a drug reservoir. Some devices may be removably attached to a drug reservoir, for example, through a luer connector. Other devices may comprise internal luer seal for securely connecting a drug conduit of the device to the luer cavity of a drug reservoir. Yet other devices may comprise a priming-enabling element to facilitate the drug priming of a shielded needle. Related methods and systems comprising the devices are also described. | 02-06-2014 |
20140046292 | Method Of Drug Delivery For PTH, PTHrP And Related Peptides - The present invention provides compositions, devices, methods and processes related to the intradermal delivery of PTHrP and PTHrP analogues, particularly [Glu | 02-13-2014 |
20140046293 | Method Of Drug Delivery For PTH, PTHrP And Related Peptides - The present invention provides compositions, devices, methods and processes related to the intradermal delivery of PTHrP and PTHrP analogues, particularly [Glu | 02-13-2014 |
20140046294 | DEVICE AND METHOD FOR DISCHARGING A REACTIVE LIQUID - A device and method for dispensing a liquid with a gas includes an instrument having a cannula and a low-pressure tip. The low-pressure tip includes a tip housing that at least partially defines a high pressure chamber. A distal wall of the tip housing includes an aperture in fluid communication with the high pressure chamber. The low-pressure tip also includes a tube and a gas flow channel. The tube fluidly communicates liquid at a relatively low pressure from the cannula through the first aperture. The gas flow channel fluidly communicates gas from the cannula at a relatively high pressure and to the high pressure chamber for discharge from the aperture. The tube and aperture are adapted to dispense the liquid and the gas in order to create a low pressure zone distal of the tube to dispense droplets of the liquid. | 02-13-2014 |
20140052096 | PUMP ENGINE WITH METERING SYSTEM FOR DISPENSING LIQUID MEDICATION - An infusion pump system is disclosed for dispensing liquid medication, such as insulin. The infusion pump system includes a first reservoir for storing liquid medication, a first fluid driver for exerting pressure on the first reservoir, a second reservoir for storing liquid medication, and a second fluid driver for exerting pressure on the second reservoir. One or more valves are used to permit flow of liquid medication from the first reservoir to the second reservoir, and to permit flow of liquid medication from the second reservoir to an infusion site. Each of the valves is selectively opened or closed to fill the second reservoir with liquid medication from the first reservoir and to dispense liquid medication from the second reservoir to the infusion site. A controller and one or more sensors are used to monitor and control the system. | 02-20-2014 |
20140052097 | GUIDE EXTENSION CATHETER - Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a guide extension catheter. The guide extension catheter may include an elongate tubular member having a proximal region, a distal region, and a slot formed in the tubular member between the proximal region and the distal region. The proximal region of the tubular member may be configured to shift between a first configuration and a collapsed configuration. The guide extension catheter may also include an elongate shaft for shifting the proximal region between the first configuration and the collapsed configuration. | 02-20-2014 |
20140052098 | Retractable Safety Syringe with Non-Loaded Seal - A retractable safety syringe may have a needle, a syringe body, a shaft seal, and a plunger assembly. A proximal portion of the body and a piston of the plunger may define a vacuum chamber. The plunger assembly may comprise a shaft coupled to a piston. The shaft may have at least one non-engaging portion and at least one engaging portion. The plunger assembly is movable between a storage position and working positions. In the storage position, little or no force is exerted on the shaft seal by the non-engaging portion. In the working positions, the engaging portion is in sealing engagement with the shaft seal to seal the vacuum chamber. Stopper movement of the retractable safety syringe may be reduced or eliminated if the retractable safety syringe is prefilled. | 02-20-2014 |
20140052099 | INJECTION NEDDLE ASSEMBLY AND MEDICINE INJECTION DEVICE - A needle tube having a needle tip for puncturing skin; a needle hub; and a fluid-draining portion for enabling draining of a medicine. The needle hub includes: a retention part (first member) for retaining the needle tube; an insertion part into which the output portion of a syringe is inserted; and a flange-like skin contact portion that is disposed in a manner so as to cover an area surrounding the needle tube and makes contact with and/or faces the skin when a living body is punctured with the needle tube. The fluid-draining portion is disposed in the skin contact portion of the needle hub and enables a user to drain the medicine that has spilled when removing air and is held in the skin contact portion. | 02-20-2014 |
20140052100 | INJECTION NEEDLE ASSEMBLY AND MEDICINE INJECTION DEVICE - A needle tube having a needle tip for puncturing skin; a needle hub; and an absorption part for absorbing a medicine. The needle hub includes: a retention part (first member) for retaining the needle tube; an insertion part into which the output portion of a syringe is inserted; and a flange-like skin contact portion that is disposed so as to cover an area surrounding the needle tube and that makes contacts with and/or faces the skin when a living body is punctured with the needle tube. The absorption part is disposed in the skin contact portion of the needle hub and absorbs medicine that has been spilled during air removal and is held in the skin contact portion so as to thereby prevent the medicine from attaching to or contacting the skin of a user. | 02-20-2014 |
20140052101 | Devices, Assemblies and Methods for Controlling Fluid Flow - A valve is provided for controlling flow along a fluid line that includes an outer shell and an inner housing slidably disposed therein that includes connector threads surrounding a boss on one end and a passage through the boss. A backing member is coupled to the outer shell and has a sealing pin extending into the passage. The inner housing is movable helically relative to the outer shell from a closed position wherein a sealing pin engages an outlet opening at the distal end of the boss to seal the opening and an open position in which the inner housing is directed away from the sealing pin to open a fluid path through the valve. A torque limiter mechanism between the outer shell and inner housing resists movement from the valve closed position to the valve open position until a selected torque level is reached. | 02-20-2014 |
20140052102 | Reuse Protection for Disposable Parts - The present invention inter-alia relates to an apparatus comprising a receiving opening configured to receive a connecting part of a medical device in a spread condition of the receiving opening and to block receiving the connecting part of the medical device in a relaxed condition of the receiving opening, and a spreader configured to spread the receiving opening in the spread condition such that an opening diameter of the receiving opening is at least as big as an outer diameter of the connecting part of the medical device. | 02-20-2014 |
20140058353 | Subcutaneous Infusion Device - An infusion system having an integrated inserter and infusion set ( | 02-27-2014 |
20140058354 | Huber Needle Safety Enclosure - A method of using a safety enclosure for a needle, the needle including an aft end and a fore end together forming a right angle, the fore end including a sharp outer end. The method includes providing a safety enclosure including a needle housing and a panel unit, the needle housing having a finger pad, orienting the safety enclosure in a desired location for insertion of the needle, and applying pressure to the finger pad sufficient to cause penetration of the needle at the desired location and to move the panel unit to the installation position. | 02-27-2014 |
20140058355 | HOLLOW CURVED SUPERELASTIC MEDICAL NEEDLE AND METHOD - A needle assembly | 02-27-2014 |
20140066891 | Devices and Methods for Modulating Medium Delivery - Devices, systems and methods for controlling, regulating, altering, transforming or otherwise modulating the delivery of a substance to a delivery site. The devices, systems and methods optimize the delivery of the substance to an intended site, such as a vessel, vascular bed, organ and/or other corporeal structures, while reducing inadvertent introduction or reflux substance to other vessels, vascular beds, organs, and/or other structures, including systemic introduction. | 03-06-2014 |
20140066892 | INSULIN ON BOARD COMPENSATION FOR A CLOSED-LOOP INSULIN INFUSION SYSTEM - An electronic controller for an insulin infusion device includes a processor architecture and at least one memory element. The memory element stores executable instructions that, when executed by the processor architecture, provide an insulin on board (IOB) compensation module to estimate a current IOB value that indicates an amount of active insulin in the body of the user, calculate an IOB rate based at least in part on the estimated current IOB value, determine an adjusted insulin infusion rate based at least in part on the calculated IOB rate and an uncompensated insulin infusion rate, select a final insulin infusion rate for the device, and provide the selected final insulin infusion rate to regulate delivery of insulin by the device. | 03-06-2014 |
20140066893 | Roller Clamp - A roller clamp includes at least two opposing and spaced apart side walls, a guide wall, a further wall opposite the guide wall defining an aperture therethrough, a hollow body and a roller. The hollow body has a body aperture therethrough. The roller comprises a roller wheel having two axial projections protruding from a center of each side of the roller. Each side wall is provided with an opposing guide groove on the interior surface thereof. The two axial projections of the roller wheel are slidingly seated in the guide grooves so that the roller can move in the aperture of the further wall as the projections slide in the grooves. At least one respective long edge of each corresponding guide groove is provided with at least one notch. The resulting at least one pair of corresponding notches can at least partially seat the two projections. | 03-06-2014 |
20140066894 | Self-Sealing Pad for a Needle-Based Infusion Set - A safety needle assembly of an infusion set is disclosed. The needle assembly is configured to prevent fluid/vapor escape therefrom so as to reduce or prevent fluid exposure to a clinician using the needle assembly. In one embodiment, the needle assembly comprises a handle portion including a needle extending therefrom, the needle defining a lumen for passage of a fluid therethrough. The needle assembly also includes a safety assembly defining a needle hole through which the needle initially extends. The safety assembly is selectively and axially slidable along the needle in order to shield a distal tip of the needle and prevent user contact therewith. A fluid isolation component is included in the safety assembly for isolating fluid escape from the needle. In one embodiment, the fluid isolation component includes a self-sealing pad that prevents needle leakage when the distal tip is shielded by the safety assembly. | 03-06-2014 |
20140074062 | PISTON PUMP DEVICES - Drug pump devices with syringe or pen-injection configurations may utilize pre-filled drug vials or cartridges; the prefilled vials may be equipped with mechanisms for stirring their contents and/or changing a chemical environment therein to improve therapies. To facilitate combination therapies, multiple drug pump devices may be assembled into a larger system. Lancet insertion devices for use in conjunction with the drug pump devices may feature improved safety characteristics and/or mechanisms for minimizing pain and discomfort. | 03-13-2014 |
20140074063 | THERMOCHEMICAL ABLATION OF BODILY TISSUE - Thermochemical ablation techniques may provide ablation of bodily tissue using chemical reaction energy. | 03-13-2014 |
20140074064 | INTRADERMAL DELIVERY DEVICE INCLUDING A NEEDLE ASSEMBLY - A drug delivery device including a needle assembly facilitates making intradermal injections using a variety of drug container types such as a syringe. A hub supports the needle while a limiter surrounds the needle. The limiter includes a skin engaging surface that is adapted to be received against the skin of an animal to be intradermally injected. A forward end of the needle extends beyond the skin engaging surface a selected distance to limit a depth that the needle penetrates into the animal's skin. | 03-13-2014 |
20140081237 | HAND-HELD MICRO-LIPOSUCTION ADIPOSE HARVESTER, PROCESSOR, AND CELL CONCENTRATOR - Devices and methods are provided for aspirating adipose tissue with a portable device. This device may include a processing chamber, a cannula, a vacuum source, a filter or screen for separating connective tissue strands from adipose tissue, a digestion area, and a product cell concentration chamber. | 03-20-2014 |
20140081238 | METHOD OF RECONSTITUTING A SUBSTANCE USING AN INJECTOR DEVICE - The present invention is directed to an automatic reconstitution drug delivery device. The inventive device effects simple and automatic reconstitution of a dry drug. To effect reconstitution, a user displaces a release button which causes first and second chambers of a drug cartridge to communicate, resulting in automatic mixing of a diluent and dry drug to effect reconstitution of the dry drug. The user then simply sets the dose volume using a dose-setting mechanism, and administers the injection in a manner typical of self-injection drug delivery devices. Whole or partial automatic priming can be also achieved by the device. | 03-20-2014 |
20140081239 | INJECTION DEVICE - An injection device ( | 03-20-2014 |
20140088549 | Angled Inserter For Drug Infusion - An infusion set adapted to be secured to a skin surface includes a fixed base member and a movable slide member. The fixed base member is connectable to the skin surface. The movable slide member has a needle or cannula connected thereto and is movable relative to the fixed base member. The movable slide member is movable from a first position in which the needle or cannula is not exposed externally of the fixed base member to a second position in which the needle or cannula is exposed externally of the fixed base member. The movable slide member is locked to the fixed base member in the second position. | 03-27-2014 |
20140088550 | PERPENDICULAR INFUSION SET AND DISPOSABLE INSERTER - An infusion set is disclosed that includes an inserter including an inserter housing having at least one flexible arm for holding an infusion set in a single axial position prior to insertion of at least a portion of a cannula of the infusion set, the inserter housing having a surface for contacting the patient's skin. The inserter also includes a movable plunger disposed within the inserter housing for releasing the infusion set from the inserter housing, impacting the infusion set, and imparting momentum to the infusion set to insert the cannula into the patient's skin. The inserter additionally includes a biasing element biasing the plunger toward the activated position. | 03-27-2014 |
20140088551 | CARTILAGE REPAIR, PRESERVATION AND GROWTH BY STIMULATION OF BONE-CHONDRAL INTERFASE AND DELIVERY SYSTEM AND METHODS THEREFOR - Therapeutics and methods of treatment to repair, preserve and grow cartilage are presented. In addition, systems and methods for delivering a therapeutic to a hard to reach anatomical area, such as, for example, the BCI, are presented. A cannulated delivery device provided with a cutting tip, cutting flutes and threads on its distal end is disclosed, as well as therapies for joint and cartilage repair, preservation and generation using it. Alternatively, for disc repair, a “PIARES” device for Percutaneous Intradiscal Annular Repair introduces therapeutics intradiscally. The device may have two-needles; a first cannula/needle with a finger grip, and a longer inner needle to penetrate through the outer needle into the disc, and introduce therapeutics via a syringe. When provided with a septum at the inner needle's proximal end, the PIARES device is a completely closed system; using it minimizes trauma. | 03-27-2014 |
20140088552 | Intravitreal Injection Device - The present disclosure provides a new and improved intravitreal injection device, which is capable of locating the injection site with precision and reproducibility, ensuring the smooth delivery of medications or other treatments, and reducing potential need contaminations. In various embodiments, the device comprises a head unit and a hollow stem extending orthogonally from a bottom of the head unit. The device additionally includes a locating foot slidingly disposed on a distal end of the stem and a biasing device structured to bias the locating foot toward an extended position. | 03-27-2014 |
20140088553 | RETRACTABLE PLUNGER DESIGN FOR INJECTION CONTROL DEVICE FOR PROPORTIONAL INJECTION EXTRACTION DURING THE SYRINGE'S INSERTION EXTRACTION - An injection control device (ICD) for a syringe, injects/extracts material into/from at a rate controllably proportional to the rate of movement of the syringe. A transmission reference member is extendable outward from the ICD body, being connected to a transmission system/clutch which has an engage/disengage trigger for independent movement of a plunger arm. The ICD, via the transmission translates motion from movement of the body, in relation to a fixed state of the transmission reference member, to action on the plunger of an accommodated syringe. The clutch also allows the transmission reference member to be positioned, without transferring power to the transmission system. | 03-27-2014 |
20140088554 | DRUG-DELIVERY PUMP WITH INTELLIGENT CONTROL - Embodiments of the present invention utilize a closed-loop feedback control system to ensure accurate drug delivery. This control system may, for example, utilize a flow sensor to measure the volume of delivery and an intelligent control algorithm to anticipate and compensate for overdoses and underdoses. Feedback control systems in accordance herewith can be applied to any piston- or plunger-driven pump system utilizing sensors that measure flow directly or indirectly. Depending on the mode of operation, fluid may be dispensed continuously or in discrete pulses, and the manner of adjustment or calibration may be tailored to the operational mode in use. | 03-27-2014 |
20140088555 | Systems and Methods for Electrolysis Pump Control - Drug-delivery devices may utilize electrolysis pumps to push a plunger so as to deliver drug from a reservoir. The volume and/or rate of drug delivery may be monitored based on pressure measurements in the pump chamber. Pressure signatures characteristic of end-of-dose and occlusion events may be used to detect when plunger movement stops. | 03-27-2014 |
20140088556 | RESERVOIR FLUID VOLUME ESTIMATOR AND MEDICAL DEVICE INCORPORATING SAME - Apparatus are provided for infusion devices and related control systems and methods. In one embodiment, an infusion device includes a voided portion adapted to receive a shaft portion that includes a shaft coupled to a plunger of a reservoir. The shaft portion includes a detectable feature having an optically detectable pattern such as gray code, and the infusion device includes a sensing arrangement having an optical sensor proximate the voided portion to sense the detectable feature. In some embodiments, a control module is coupled to the sensing arrangement to determine a remaining amount of fluid in the reservoir based at least in part on the sensed position of the detectable feature. In embodiments, the optical sensor detects the sensed position of the shaft based on the detectable feature only when the reservoir is replaced and/or after each delivery of fluid to reduce power consumption. | 03-27-2014 |
20140088557 | Infusion Pump System - An infusion pump system is described that increases patient comfort and convenience. The infusion pump system includes an infusion site interface that is releasably connected to an infusion pump body, and has no tubing associated between the infusion site interface and the pump body. The infusion pump body may include a carrier frame that may be adhered to the skin of a user. | 03-27-2014 |
20140088558 | USE OF SWITCHES TO FACILITATE A SAFE AND CONVENIENT ATTACHMENT AND REMOVAL PROCEDURE - The present invention inter alia relates to an apparatus, comprising a detecting arrangement comprising a first and a second detecting unit, wherein the detecting arrangement is configured to at least detect a partial attaching of an attachable unit to the apparatus and a complete attaching of the attachable unit to the apparatus, wherein the attachable unit is configured to be removably attached to the apparatus, and wherein the detecting arrangement is configured to only enable at least one function of the apparatus, when a complete attaching of the attachable unit to the apparatus is detected. | 03-27-2014 |
20140094767 | IMPLANT INSERTION SYSTEM - A needle shell is inserted through skin with a needle insert within the needle shell occluding an insertion end of the needle shell. The needle insert is withdrawn from the needle shell and an implant tube is inserted into the needle shell and below the skin. An implant insertion rod is inserted into the needle shell to implant an implant below the skin. | 04-03-2014 |
20140094768 | Movable magnet for magnetically guided catheter - A catheter is disclosed having a flexible tubing with a proximal end and a distal end. The catheter comprising at least one movable magnet provided within the distal end of the flexible tubing. A control mechanism is operable to selectively activate the at least one movable magnet from the proximal end of the flexible tubing. The at least one movable magnet is responsive to an external magnetic field to position and guide the distal end of the flexible tubing within a body of a patient. | 04-03-2014 |
20140094769 | GAS-PRESSURED MEDICATION DELIVERY SERVICE - The present invention relates to medical devices and particularly to a medication delivery device for self-injection of a medication, or for healthcare professionals to administer a medication. In one embodiment, a medication delivery device utilizes a source of gas pressure to deploy a needle, deliver a desired amount of medication through the needle, and retract the needle for disposal. Fluid flow paths from the source of gas pressure communicate the gas pressure to the needle and to the medication in order to accomplish these steps. In one embodiment, a valve is positioned to open and close the flow of the pressurized gas to the needle and the flow of the medication to the needle, so that the valve can be operated to deploy the needle and deliver the medication through the needle when the user is ready for the injection. The valve can also be operated to retract the needle when the dose is complete. | 04-03-2014 |
20140094770 | DRUG-DELIVERY PUMP WITH INTELLIGENT CONTROL - Embodiments of the present invention utilize a closed-loop feedback control system to ensure accurate drug delivery. This control system may, for example, utilize a flow sensor to measure the volume of delivery and an intelligent control algorithm to anticipate and compensate for overdoses and underdoses. Feedback control systems in accordance herewith can be applied to any piston- or plunger-driven pump system utilizing sensors that measure flow directly or indirectly. In some embodiments, adjustments are made during a “priming” stage when liquid is pumped through the internal fluid path but does not exit the pump. | 04-03-2014 |
20140094771 | DRUG-DELIVERY PUMP WITH INTELLIGENT CONTROL - Embodiments of the present invention utilize a closed-loop feedback control system to ensure accurate drug delivery. This control system may, for example, utilize a flow sensor to measure the volume of delivery and an intelligent control algorithm to anticipate and compensate for overdoses and underdoses. Feedback control systems in accordance herewith can be applied to any piston- or plunger-driven pump system utilizing sensors that measure flow directly or indirectly. In some embodiments, adjustments are made based on the flow “tail” that occurs in a piston- or plunger-type pump as relaxation of the plunger material continues to push fluid out of the drug reservoir; this residual flow eventually ceases after the plunger returns to its natural state. | 04-03-2014 |
20140094772 | Methods for Detecting Failure States in a Medicine Delivery Device - A fluid medicament delivery device includes a patient attachment unit, containing the fluid medicament, and an indicator unit adapted to be detachably coupled to the patient attachment unit. A method for monitoring the fluid medicament includes independently setting a flow rate of a fluid medicament with the patient attachment unit. A pressure and/or a flow rate of the fluid medicament is sensed with a sensor located in a separate indicator unit in a sensing mode. A status of the fluid medicament delivery device is determined based at least in part on the pressure and/or the flow rate. | 04-03-2014 |
20140094773 | ADJUSTABLE LENGTH CATHETER AND METHOD OF USE - An adjustable length catheter is disclosed. In some embodiments, the catheter is configured for use with a hub configured to couple to an end of the catheter. A cutting tool and/or a flaring tool may further be provided in connection with the catheter. In some embodiments, these tools are coupled to a hub member. The catheter may be configured such that a user, for example a medical practitioner, may cut the catheter to a desired size as part of a therapy or other procedure. | 04-03-2014 |
20140094774 | Guidewire Extension System for a Catheter Placement Device - An insertion tool for inserting a catheter into a patient's body is disclosed. The insertion tool unifies needle insertion, guidewire advancement, and catheter insertion in a single device. In one embodiment, the insertion tool comprises a housing in which at least a portion of the catheter is initially disposed, a hollow needle distally extending from the housing with at least a portion of the catheter pre-disposed over the needle, and a guidewire pre-disposed within the needle. A guidewire advancement assembly is also included for selectively advancing the guidewire distally past a distal end of the needle in preparation for distal advancement of the catheter. In one embodiment a catheter advancement assembly is also included for selectively advancing the catheter into the patient. Each advancement assembly can include a slide or other actuator that enables a user to selectively advance the desired component. Guidewire and catheter advancement assemblies are also disclosed. | 04-03-2014 |
20140094775 | CATHETER/FISTULA NEEDLE TO BLOODLINE CONNECTION ASSURANCE DEVICE - In general, multiple embodiments of a catheter/fistula needle to bloodline connection assurance device, which secures and strengthens a connection between an extension tube end of a catheter or fistula needle and a bloodline, are provided. One embodiment includes internal and external clamshells. Internal clamshell halves pressure seal to the bloodline connector, and form outwardly extending barbs. The external clamshell opens rotatably about at least one hinge and includes inwardly facing threads that catch the outer barbs of the internal clamshell. After a user connects the catheter or fistula needle to the bloodline, the user closes the internal clamshell about the bloodline connector. Then, the user closes the external clamshell about the internal clamshell, causing the inwardly facing barbs of the external clamshell to engage the outwardly facing barbs of the internal clamshell. Such engagement prevents axial movement of the bloodline connector relative to the external clamshell. | 04-03-2014 |
20140094776 | INJECTION DEVICE WITH AUTOMATED SUBSTANCE COMBINING FEATURE - An injection device for automatically combining two substances, including a body and a cartridge displaceably disposed within the body having a first chamber for containing a first substance, a second chamber for containing a second substance, a first stopper displaceably disposed within the cartridge separating the first and second chambers, a second stopper displaceably disposed within the cartridge defining an end of the second chamber. The device also includes a needle hub displaceably disposed within the body having threads thereon for connecting a pen needle to the injection device. The device additionally includes a plunger displaceably disposed within the body, a biasing member, a sleeve, biased by the biasing member and communicating the bias to the plunger, and an activation button radially displaceable with respect to the body to selectively release the sleeve to drive the plunger and automatically mix the first and second substances. | 04-03-2014 |
20140100544 | INFUSION SET WITH SAFETY DEVICE - An infusion set includes a base with a rigid piercing cannula or a soft catheter and rigid introducer needle. The infusion set also includes a line set with a fluid connector. The base and line set are configured such that the fluid connector can be used as a protector for the piercing cannula or the soft catheter, either before the device is attached to a user, or after the device is detached from the user, or both. | 04-10-2014 |
20140100545 | INSULIN PUMP HAVING MISSED MEAL BOLUS ALARM - A pump for delivering insulin to a user. The pump comprises a pump mechanism and a meal-bolus program module. The meal-bolus program module is programmed to control the pump mechanism to deliver a meal bolus. An alarm program module is in data communication with the alarm, the timer, and the meal-bolus program module. The alarm module is programmed to generate an alarm signal when the meal-bolus program module does not control the pump mechanism to deliver a meal bolus within a predetermined period of time. | 04-10-2014 |
20140100546 | Syringe Having A Collapsible Plunger Rod - A syringe assembly includes a syringe barrel having an exterior surface, an inside surface defining a chamber, an open proximal end, a distal end, and an outlet disposed adjacent the distal end in fluid communication with the chamber; and a plunger assembly disposed at least partially within the syringe barrel. The plunger assembly includes an elongated plunger rod and a plunger head. The elongated plunger rod is associated with the plunger head to move the plunger head within the chamber of the syringe barrel through an injection cycle. The plunger rod is adapted to move from a collapsed position extending alongside the exterior surface of the syringe barrel to an extended position engaging the plunger head to move the plunger head through the injection cycle. | 04-10-2014 |
20140107611 | CONTROLLING FLOW IN A MEDICAL INJECTION SYSTEM - A valve apparatus for a medical injection system includes a pinching member and at least one spring-loaded anvil. A tubing line of the injection system may be positioned between the pinching member and the anvil, such that when the pinching member is moved into a pinching position adjacent to the anvil, for example, by rotation of a shaft to which the member is coupled, the pinching member compresses the tubing line against the spring-loaded anvil. The pinching member is preferably rotatable about an auxiliary axis, which is eccentric, or offset from a central axis of the shaft. A spring member of the spring-loaded anvil is preferably pre-loaded. In certain applications, the pinching member, when moved into the pinching position, applies a pinching force of greater than approximately 45 pounds, for example, to prevent flow through the tubing line at an injection pressure of up to approximately 1200 psi. | 04-17-2014 |
20140107612 | Protection against spill and syringe related contamination - Methods and apparatus for employing an adhesive strap about a medical connection for improving connection integrity for greater safety and reliability and a cross contamination barrier for medical syringes is disclosed. Also, a shielding tube for a medical syringe which acts as a barrier against cross contamination across a syringe plunger is disclosed. The tube comprises a pattern of raised ribs inside to protect against potentially tube tearing edges of an associated plunger rod assembly and to provide a skid resistant surface when disposed about flanges of the syringe. | 04-17-2014 |
20140107613 | SYSTEM AND METHOD FOR DETECTING OCCLUSIONS IN A MEDICATION INFUSION SYSTEM USING PULSEWISE PRESSURE SIGNALS - A medical fluid communication system is disclosed comprising a pump controller and a fluid detector. The fluid detector detects characteristics of the fluid and provides fluid measurements to the pump controller, which detects if the fluid is flowing in the medication delivery system. In the event fluid is not flowing due to an occlusion, the pump controller may attempt to resolve the occlusion or may provide a warning to a user that an occlusion is occurring. | 04-17-2014 |
20140114279 | MODULATION NEURAL PATHWAYS - An administration device comprising an array of needles, one or more fluid agents, and at least one hydrogel is described. The device can simultaneously deliver a plurality of fluid agents along respective axes into a tissue. The use of hydrogel leads to constrained delivery of the fluid agents. The constrained delivery of an agent is also achieved by depositing a drug implant into a tissue. The effect of an agent on the tissue can be evaluated thereafter. In addition, the invention is directed to treating muscle diseases by delivering a therapeutic agent in vivo, and the use of reporter tissues for candidate drug evaluation, detecting and characterizing resistance. | 04-24-2014 |
20140114280 | MATERIALS AND METHODS FOR REPAIR OF CARTILAGE DEFECTS - In one embodiment, the present invention includes a method for repairing a cartilage defect including: preparing a cartilage defect by removing unwanted or damaged tissue; creating at least one perforation into or through subchondral bone, below and/or adjacent to the cartilage defect to induce the flow of bone fluid; allowing the bone fluid to bleed through the at least one perforation up into the cartilage defect to fill at least a portion of the cartilage defect; and applying a biomaterial into the defect to produce a clot for cartilage regeneration. | 04-24-2014 |
20140114281 | LAUNCHER FOR ANIMAL TREATMENT - A launcher for remotely treating an animal is described. The launcher having a first chamber adapted to receive a first dosage projectile having a first calibre, a second chamber adapted to receive a second dosage projectile having a second caliber smaller than the first calibre, a launcher barrel comprising a first cooperating caliber facilitating launching of the first dosage projectile, an adaptor comprising a second cooperating caliber facilitating launching of the second dosage projectile, and a propulsion assembly for propelling the dosage projectiles. An adaptor is also described, for adapting the launcher to launch dosage projectiles of calibers other than those associated with the launcher barrel. | 04-24-2014 |
20140114282 | Patch-Sized Fluid Delivery Systems and Methods - A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device. | 04-24-2014 |
20140121636 | SYSTEMS AND METHODS FOR GUIDING INJECTIONS - Systems and methods are described herein for guided injection, which include: one or more controllable light-emitting elements configured to emit non-destructive light and a computing device operably connected to the one or more controllable light-emitting elements configured to emit non-destructive light, the computing device including a processor operable to receive at least one digital representation of a body region of an individual, the body region of the individual including one or more physical registration landmarks, the at least one digital representation including one or more digitally registered injection sites and one or more digital registration landmarks corresponding to the one or more physical registration landmarks on the body region; and control the one or more controllable light-emitting elements to illuminate a location of a surface of the body region of the individual corresponding in location to at least one of the one or more digitally registered injection sites. | 05-01-2014 |
20140121637 | SYSTEMS AND METHODS FOR GENERATING AN INJECTION GUIDE - System and methods are described herein for generating an injection guide, which include receiving one or more digital images of a body region of an individual, the body region including one or more physical registration landmarks, generating at least one digital representation of the body region using the one or more digital images, the at least one digital representation including one or more digital registration landmarks corresponding to the one or more physical registration landmarks on the body region, adding one or more digitally registered injection sites to the at least one digital representation of the body region in an injection-treatment pattern, the one or more digitally registered injection sites registered relative to the one or more digital registration landmarks, and generating one or more output signals having information for controlling one or more controllable light-emitting elements to illuminate a location on a surface of the body region of the individual corresponding in location to at least one of the one or more digitally registered injection sites. | 05-01-2014 |
20140121638 | DRESSING FOR USE WITH AN INFUSION KIT - A dressing, for use in securing an infusion set on a skin surface, the dressing consisting of a film having a skin contacting surface and a non-skin-contacting surface, the skin-contacting surface being provided with an adhesive; a releasable backing layer provided on the non-skin-contacting surface of the film; a releasable liner provided on the skin-contacting surface of the film layer and overlaying the adhesive wherein an aperture is provided having a first portion extending from an edge of the film, backing layer and liner opening into a second portion having a geometry which is identical or substantially similar to the geometry of the perimeter of the hub of an infusion set, and wherein at least one handle is provided between the film and the liner. | 05-01-2014 |
20140128840 | Shroud Deployment in Automatic Injection Devices - Exemplary embodiments provide automatic injection devices in which a shroud is automatically deployed to protectively sheath a needle after an injection is performed. Exemplary embodiments also provide shroud deployment assemblies including a shroud and a syringe carrier that, when cooperatively configured in an automatic injection device, ensure that the shroud is automatically and completely deployed after an injection is performed using the automatic injection device. Exemplary embodiments are also configured to ensure that, once the shroud is deployed to an extended position to sheath the needle, accidental forces applied to the shroud do not succeed in subsequently retracting the shroud to a retracted position in which the needle would become exposed. | 05-08-2014 |
20140128841 | Controlled Injection Devices, Systems, and Methods - Medical devices are described herein. More particularly, the disclosure relates to controlled injection devices, systems, and methods used for the introduction of treatment material into a cavity. An exemplary controlled injection system comprises an injection device and a jig. The jig is adapted to receive the injection device and has a jig head, jig shaft, and a jig housing. | 05-08-2014 |
20140128842 | Medicament Administration - A system comprises a pad and an injection device. A first side of the pad is configured to be attached to a skin of a user; the pad is provided with coded information; the injection device is configured to read the coded information from the pad when the injection device is brought into proximity of or contact with the pad; the injection device is configured to determine whether the coded information on the pad meets a predetermined criterion; and the injection device is configured to respond to a positive determination by autoinjecting medicament through the pad into the user, permitting medicament administration, or indicating to the user that medicament administration is appropriate. The pad and the injection device also are separate aspects. | 05-08-2014 |
20140128843 | DRUG DELIVERY DEVICE WITH ELECTRO-MECHANIC DRIVE MECHANISM - The present invention relates to a drug delivery device for setting and dispensing of a dose of a medicament is presented comprising a housing to accommodate a cartridge filled with the medicament, an electrically operated drive mechanism to be operably engaged with the cartridge to expel a predefined dose of the medicament from the cartridge, and at least one dose element displaceably arranged relative to the housing to set and/or to dispense the dose of the medicament, wherein the dose element and the drive mechanism are mechanically decoupled from each other. | 05-08-2014 |
20140135733 | METHODS FOR INJECTING A DRUG INTO PROSTATE TISSUE - Method and surgical instrument for treating prostate tissue including a surgical instrument having a main body, a needle deployment port, a needle, first and second handles and a lockout release mechanism to limit needle extension. Additionally, a kit includes the surgical instrument, together with a cystoscope, and optionally a syringe and reservoir of ethanol. The method includes needle-less injection and visualizing the ethanol injection by delivering both an echogenic agent and ethanol either by needle or needle-less injection or by providing an ultrasonically visible marker near the tip of the ethanol delivery cannula. The method also includes extending the needle transversely of the instrument housing using a link assembly. | 05-15-2014 |
20140142541 | MECHANICALLY ROBUST FAST-DISSOLVING MICRONEEDLES FOR TRANSDERMAL DRUG AND VACCINE DELIVERY - Disclosed are biocompatible, dissolving microneedle structures with enhanced mechanical strength. More particularly, the present disclosure relates to microneedles containing nanomaterials. Also disclosed are methods of producing such microneedle structures, as well as methods for using them to deliver drugs or biomolecules into the skin or epithelia, or the cytoplasm and/or nucleus of a skin or epithelia cell, of a subject. | 05-22-2014 |
20140142542 | Catheter and Support Cannula Assembly - A system may include a catheter and a support cannula within the catheter. The catheter may include a tapered tip and a body extending proximally therefrom. The catheter tip may have a smaller inner diameter than the catheter body. The support cannula may include a tip disposed within the catheter tip such that the support cannula tip does not extend distally beyond the catheter distal end and a support segment extending proximally from the support cannula tip and disposed within the catheter body such that the catheter body remains in a non-stretched configuration. An outer diameter of the cannula tip may correspond to the inner diameter of the catheter tip. An outer diameter of the support segment may correspond to the inner diameter of the catheter body. The support segment may extend proximally to at least a proximal end of a perforated segment of the catheter body. | 05-22-2014 |
20140142543 | Methods and apparatus for lancet actuation - A lancet driver is provided wherein the driver exerts a driving force on a lancet during a lancing cycle and is used on a tissue site. The driver comprises of a drive force generator for advancing the lancet along a path into the tissue site, and a manual switch for a user interface input. | 05-22-2014 |
20140142544 | MEDICATION INJECTOR APPARATUS WITH DRIVE ASSEMBLY THAT FACILITATES RESET - A medication injector apparatus such as an injection pen. The injection pen includes a resettable, cartridge plunger drive assembly including an axially floating nut, a cartridge plunger engaging screw, and a drive clutch movable with the nut and which when rotated causes the screw to screw through the nut. When a cartridge assembly is mounted to the pen base, the floating nut and drive clutch are shifted proximally such that the drive clutch is in torque transmitting engagement with a rotatable drive member of the pen, such that rotation of that drive member results in drive screw advancement through the nut in the distal direction. When the cartridge assembly is not mounted to the pen base, the floating nut and drive clutch are biased distally to disengage the drive clutch from torque transmitting engagement with the rotatable drive member and to thereby allow the drive screw to be reset proximally through the nut to a position more retracted within the pen base. The injection pen also may include an injection clicker assembly having a collar arranged coaxially on a drive sleeve and which oscillates axially on the drive sleeve that rotates during medication dispensing to provide an audible clicking sound that indicates injecting use of the pen. The injection pen also may include a doseable quantity identifier that uses a rotational matrix and a sensor for electrically sensing the arrangement of the dose setting mechanism of the pen, which identifier may be part of a therapeutic dose indicating system that utilizes a cartridge recognizer to recognize a concentration of medication so as to allow an automatic determination of a therapeutic dose. The injection pen further may include an assembly for selectively rotating a drive sleeve of the pen, which assembly has a dial that rotates out during dose setting and which translates in without rotation during dose injecting. | 05-22-2014 |
20140148780 | Catheter with Depth Electrode for Dual-Purpose Use - A catheter assembly for intracranial treatment of a patient for facilitating concurrent electrical sensing and fluid flow is provided and includes an outer flexible tube having a proximal end, a principal lumen extending therealong to the proximal end, and at least one radial aperture through the wall communicating with the lumen as well as a secondary lumen adjacent to the tube outer-wall surface and extending therealong. The catheter assembly including a depth electrode within the secondary lumen, extending along the length thereof. The depth electrode having electrical contacts exposed to brain tissue along the flexible tube. | 05-29-2014 |
20140148781 | Methods and Apparatus for Disinfecting and Reflux Prevention Flush Syringe Assembly - Embodiments of the invention are directed to flush syringe assemblies comprising an integrated contamination-prevention device integrated with device connector flushing positioned so that the practitioner cannot forget to apply disinfectant. The flush syringe assemblies comprise a barrel with an elongate plunger rod disposed therein and a cap comprising a passageway. The plunger rod includes a stopper of which at least a portion can be embedded in the passageway of the cap to form a plug in the cap. | 05-29-2014 |
20140148782 | TISSUE INFUSION SYSTEM AND METHOD - An apparatus and corresponding method for providing convection enhanced delivery of bioactive agent to a tissue site. The apparatus involves the use of semipermeable membranes, typically in the form of one or more hollow fibers, together with a source and conduit of solution containing the bioactive agent to be delivered. The use of hollow fiber technology provides an optimal combination of features, including delivery kinetics and distribution, as compared to conventional (e.g., standard needle) type delivery devices. | 05-29-2014 |
20140148783 | DEVICES, SYSTEMS AND METHODS FOR MEDICAMENT DELIVERY - An apparatus includes a housing, a medicament container, an actuator, and a biasing member. The actuator is configured to move the medicament container within the housing when the actuator is moved from a first configuration to a second configuration. The actuator includes a gas container and a puncturer. When the actuator is in the first configuration, a portion of the puncturer is disposed apart from the gas container. When the actuator is in the second configuration, the portion of the puncturer is disposed within the gas container. The gas container has a longitudinal axis offset from a longitudinal axis of the medicament container. The biasing member is configured to bias the actuator toward the second configuration. | 05-29-2014 |
20140148784 | WEARABLE AUTOMATIC INJECTION DEVICE FOR CONTROLLED ADMINISTRATION OF THERAPEUTIC AGENTS - Exemplary embodiments provide wearable automatic injection devices for administering a therapeutic agent to a patient's body at fast, controlled rates, for example, in a single fast bolus. Exemplary embodiments also provide methods for assembling wearable automatic injection devices for administering a therapeutic agent to a patient at fast, controlled rates. Exemplary embodiments also provide methods for using wearable automatic injection devices for administering a therapeutic agent to a patient at fast, controlled rates. | 05-29-2014 |
20140148785 | METHOD AND APPARATUS FOR DETECTING OCCLUSIONS IN AN AMBULATORY INFUSION PUMP - An improved pump, reservoir and reservoir piston are provided for controlled delivery of fluids. A motor is operably coupled to a drive member, such as a drive screw, which is adapted to advance a plunger slide in response to operation of the motor. The plunger slide is removably coupled to the piston. A method, system, and an article of manufacture for automatically detecting an occlusion in a medication infusion pump is provided. The electrical current to an infusion pump is measured. Based on a series of measurements of one or more variables, the infusion pump detects whether there is an occlusion in the system. | 05-29-2014 |
20140155861 | EXTRUSION METHODS AND DEVICES FOR DRUG DELIVERY - Disclosed herein are devices and methods for delivering agents to a solid tissue. | 06-05-2014 |
20140163518 | Safety Syringe - A safety syringe which includes an outer casing having a closed and an open end, a transition chamber having a closed and an open end, a spring assembly, and a plunger. The transition chamber is held for sliding movement within the outer casing and defines a needle concealment chamber, while the plunger defines a needle receiving chamber and is held for sliding movement within the transition chamber. A liquid medicine chamber within the transition chamber holds a precharged quantity of injectable medicine. The spring assembly is moved from its initial compressed configuration, including a needle within a needle containment chamber, when movement of the plunger and the transition chamber are moved together within the outer casing to extend the needle from a needle exit hole in the end of the outer casing. The medicine is ejected from the needle upon further movement of the plunger within the transition chamber, after which further movement of the plunger within the transition chamber retracts the needle to eject safely into the needle receiving chamber. | 06-12-2014 |
20140163519 | MEDICAL SYSTEM AND METHOD OF USE - A medical system and method can used to treat a bone. The system and method can include the preparation of bone cement to be used in the treatment. A non-liquid component and a liquid component can be combined to form a bone cement. A vacuum system can be used to saturate the non-liquid component with the liquid component. The bone cement and/or components can be heated and/or cooled. | 06-12-2014 |
20140163520 | COLLAGEN BIOMATERIAL FOR CONTAINMENT OF BIOMATERIALS - A biocompatible, resorbable collagen membrane containment member for a bone regenerative material, and a method of using such a containment member to regenerate a bone defect by surgically accessing the bone defect; disposing the containment member adjacent the bone defect, and thereafter injecting a bone regenerative material into the containment member. | 06-12-2014 |
20140163521 | MEDICAL INFUSION PUMP MECHANISM - A medical device pump with a housing with a compartment for removably receiving a cartridge containing a therapeutic agent, a conduit configured to operatively provide a fluid flow path for therapeutic agent to exit from the cartridge, a user activated delivery button, a trigger mechanism, and a pump mechanism employing an articulating, coiled drive spring. | 06-12-2014 |
20140163522 | FLUID RESERVOIR SEATING PROCEDURE FOR A FLUID INFUSION DEVICE - A method of seating a fluid reservoir in a housing of a fluid infusion device is presented here. The method is performed prior to establishing an outgoing fluid flow path from the fluid reservoir. The method begins by detecting insertion of the fluid reservoir into the housing of the fluid infusion device. In response to detecting the insertion, the method determines whether the fluid reservoir is in need of depressurization. When the fluid reservoir is in need of depressurization, the drive motor assembly of the fluid infusion device is rewound to depressurize the fluid reservoir. After depressurizing the fluid reservoir, an equalization state for the fluid reservoir is achieved. After achieving the equilibrium state, the drive motor assembly is advanced to obtain an initial seated state for the fluid reservoir. | 06-12-2014 |
20140171900 | Method to Determine a Material Distribution - A combination material can be infused into a subject and a determination can be made of a VOD and/or a convection gradient of a liquid material portion in the VOD. The combination material can be infused in the subject using selected parameters. A correlation of data relating to the liquid material can be made to a selected material to determine parameters for infusion the selected material. | 06-19-2014 |
20140171901 | DEVICE FOR RETAINING AND STORING LIQUID MEDIA AND METHOD OF EXPELLING THE LIQUID MEDIA - A device for retaining and storing a liquid medium, such as medication, includes a syringe body, a retention and/or storage container, consisting essentially of a glass material, a closure element for the retention and/or storage container consisting essentially of a rubber elastic material, and at least one needle. The retention and/or storage container is a vial having a solid bottom and a pushing device is provided to move the vial in a substantially axial direction in the syringe body, the pushing device acting upon the solid bottom of the vial. | 06-19-2014 |
20140171902 | SYSTEMS AND METHODS FOR REDUCING OR PREVENTING BACKFLOW IN A DELIVERY SYSTEM - Systems and methods are disclosed herein that generally involve CED devices with various features for reducing or preventing backflow. In some embodiments, CED devices include a tissue-receiving space disposed proximal to a distal fluid outlet. Tissue can be compressed into or pinched/pinned by the tissue-receiving space as the device is inserted into a target region of a patient, thereby forming a seal that reduces or prevents proximal backflow of fluid ejected from the outlet beyond the tissue-receiving space. In some embodiments, CED devices include a bullet-shaped nose proximal to a distal fluid outlet. The bullet-shaped nose forms a good seal with surrounding tissue and helps reduce or prevent backflow of infused fluid. | 06-19-2014 |
20140171903 | TRANSSEPTAL SHEATH WITH AIR BUBBLE TRAP - A transseptal sheath defining a sheath lumen, a proximal end, and a distal end. A valve disposed within the sheath lumen proximate the distal end. The transseptal sheath defining at least one port along a portion of its periphery proximate the valve. | 06-19-2014 |
20140171904 | DISPOSABLE PEN NEEDLE WITH RE-USE PREVENTION FEATURES - A pen needle ( | 06-19-2014 |
20140180242 | DILATION DEVICE FOR PLACING CATHETER TUBES - A stoma dilation device that includes a tubular support and an inflatable dilation portion located on the tubular support. The inflatable dilation portion includes a stiffening portion and inflation lumen. The device may have a retention portion configured to have a diameter upon full, unrestrained inflation that is greater than the diameter of the dilation portion. The device is designed to be placed in a patient to dilate the stoma for the installation of a catheter feeding tube. The device may be placed and withdrawn with the use of an endoscope which need be inserted into the patient only one time. The single insertion of the endoscope significantly reduces the trauma to the patient in comparison with multiple endoscope insertion methods. | 06-26-2014 |
20140180243 | INVENTIVE DIABETIC SYSTEMS, TOOLS, KITS, AND SUPPLIES FOR BETTER DIABETIC LIVING AND MOBILITY - A pocket sized diabetic kit carrying supplies that a diabetic patient will need for 24 hours includes but not limited to Lancet pen, lancets, small test strip bottle filled with test strips, blood test meter, one or more insulin types stored in a plurality of pre-filled syringes, one syringe splint or just one hard plunger, a plurality of alcohol pads, one blood plotter pad, Velcro straps and a syringe clipper. The pocket diabetic kit is compact, small and thin and can fit into a pocket so that a diabetic patient can be easily carried in the pants' pocket or other pockets without causing inconvenience or uncomfortable. The present invention also discloses ways to modify supplies including tools, medication syringes, etc. | 06-26-2014 |
20140180244 | LOCKING ASSEMBLY FOR PREVENTING DISPENSING OF DOSE FROM MEDICATION DISPENSING DEVICE - A locking assembly for a medication dispensing device including a housing, a drive member, a medication cartridge having a barrel holding medication between a movable plunger and a septum, and a dose delivery mechanism for controlling the advancement of the drive member. The locking assembly, in one form, includes a lock member, biased to move from a first position to a second position, with a first actuating element. The locking assembly also includes a second actuating element disposed on the drive member and cooperatively configured with the first actuating element. If the drive member of the device moves rearward from the shipped position due to a freezing of the medication, the second actuating element engages the first actuating element such that the lock member moves from the first position to the second position to lock the medication dispensing device from further dose dispensing. | 06-26-2014 |
20140180245 | DOSE GUIDES FOR INJECTION SYRINGE - Devices that guide the accurate loading and dispensing of predetermined doses of fluid from injection syringes are disclosed. | 06-26-2014 |
20140188073 | DOOR AND DOORSTOP FOR PORTABLE ONE USE DRUG DELIVERY APPARATUS - An aspect of some embodiments of the current application is a doorstop to a drug delivery apparatus that encourages a user of the apparatus to perform the proper usage steps in the proper order. For example, a user may be expected to receive an injector in a transport state, open it to an open state, insert a cartridge, and/or close the cartridge before operation. The doorstop may have an obstructing mode, optionally preventing closing of the door. The cartridge may optionally have a non-obstructing mode allowing closing of the door. Inserting the cartridge may optionally cause a doorstop to move from the obstructing mode to the non-obstructing mode. In the non-obstructing mode the doorstop may optionally prevent removal of the cartridge. | 07-03-2014 |
20140188074 | MEDICAL MARKING APPARATUS AND METHODS - The present invention provides the materials and methods related to marking the injection site on a patient's skin. Specifically, the present invention provides the materials and methods for applying a medical marking tattoo containing at least one injecting targeting site, injecting a medical substance into the area of the injection target site, and marking the injecting targeting site using a tattoo activation element. The present invention also provides the materials and methods for a medical marking apparatus that can be used to perform the methods of the present invention to mark the injection site on a patient's skin. Other embodiments are also included herein. | 07-03-2014 |
20140188075 | MEDICAMENT DELIVERY DEVICE WITH CARTRIDGE SENSOR AND CARTRIDGE HOLDER DOOR SENSOR AND METHOD OF CONTROLLING THE DEVICE - A medicament delivery device is presented for the administration of one or more drug agents, wherein the device comprises a retainer for holding a medicament cartridge. The retainer is moveable between an open and closed position. A position sensor for generating a position output is indicative of whether the retainer is in the open or closed position. Further, a cartridge sensor generates a cartridge output indicative of whether the retainer is holding a medicament cartridge. A controller controls a predetermined operation of the device in dependence on the output of the position sensor and on the output of the cartridge sensor. | 07-03-2014 |
20140188076 | Syringe Pump, and Related Method and System - A method for discharging fluid from a syringe and for mitigating occlusion conditions includes actuating the plunger of a syringe into a barrel. The method monitors fluid pressure within the barrel of the syringe and determines that an occlusion exists when the fluid pressure exceeds a predetermined threshold. The method actuates the plunger out of the barrel by a predetermined amount in response to the detected occlusion and actuates the plunger of the syringe into the barrel until a measured fluid pressure within the barrel of the syringe exceeds another predetermined threshold. | 07-03-2014 |
20140188077 | DEVICE FOR FACILITATING INTRAVENOUS NEEDLE INSERTION OR CANNULATION WITH VACUUM GENERATION MEANS AND TOURNIQUET FASTENER | 07-03-2014 |
20140194849 | REMOVABLE CLIP FOR CATHETER - A removable clip for connection with a catheter for a remote surgical procedure is provided. The clip includes a body and an arcuate concave surface configured to rest upon a central portion of the body and opposed first and second legs that each extend therefrom. A ramp surface extends from the body portion, the ramp surface with a portion that extends at an acute angle with respect to a longitudinal axis through the concave surface. A portion of the ramp surface is configured to extend within an aperture within a side wall of a catheter when the clip is fixed to the side wall of the catheter. | 07-10-2014 |
20140194850 | ACCESSORY FOR A SYRINGE - An accessory for a syringe is disclosed, including a body with a proximal end having at least one zone for application of an injection force in order to apply a force for discharging a product from the syringe, and a distal end having a bearing element for bearing against a needle mounted on the mouth of the syringe with a force that includes a radial component perpendicular to the longitudinal axis of the syringe and directed towards the centre of the syringe. An assembly including such an accessory and a syringe is also disclosed. | 07-10-2014 |
20140194851 | Flow Actuated Valve for Implantable Drug Delivery Device - An “MRI-safe” implantable infusion apparatus and method that includes a flow actuated valve (FAV) that closes to prevent a free flow of infusate to a patient during an MRI procedure, and a release mechanism that opens the valve so that the device may return to normal operation following the MRI procedure. In this manner, patient safety is improved and the inconvenience of having to empty the pump reservoir before undergoing an MRI procedure may be avoided. | 07-10-2014 |
20140194852 | MICRON-SIZED GOLD, KIT COMPRISING SAID GOLD AND ITS USE AS A NON-TOXIC IMMUNE SUPPRESSOR - Sterile micron-sized gold particles contained in capped vials, a kit of part including the vial and a liquid capable of suspending the particles, as well as their preparation, medical devices or medicaments prepared by their preparation as well as uses thereof in treating inflammation. Also, gold coated implants preferably for use in combination with the medical devices. | 07-10-2014 |
20140200545 | SYSTEM FOR OPTIMIZING A DRUG DOSAGE REGIMEN OVER TIME - A system for optimizing a patient's basal insulin dosage regimen over time, adapted to determine from blood glucose values whether and by how much to vary a patient's present recommended amount of the insulin-containing drug in order to maintain the patient's future blood glucose level measurements within a predefined range, and wherein a given blood glucose value is disregarded if no patient-actuated operation being indicative of the administration of a dose of an insulin containing drug has been detected in a pre-defined amount of time prior to the determination of the given blood glucose value. | 07-17-2014 |
20140200546 | Fluid Delivery Device And A Method of Delivering Fluid - A fluid delivery device is provided for delivering fluid to a target site such as an intervertebral disc during discography. The fluid delivery device includes pressure and volume sensors to determine the pressure and the volume of the fluid delivered to the intervertebral disc. The fluid delivery device is hand-held during use and includes a syringe assembly having a plunger with threads that enables controlled discharge of the fluid from the fluid delivery device by rotating the plunger in a housing of the fluid delivery device. The fluid delivery device includes a communication module to wirelessly transfer data to an external device outside of a sterile field, while the fluid delivery device is in the sterile field. The fluid delivery device may also include a physiological sensor to monitor involuntary pain responses based on changing physiological parameters such as increases in body temperature or blood pressure. | 07-17-2014 |
20140200547 | Method for Altering Drug Pharmacokinetics Based on Medical Delivery Platform - A method for directly delivering whereby a substance is introduced into an intradermal space within mammalian skin which involves administering the substance through at least one small gauge hollow needle having an outlet with an exposed height between 0 and 1 mm. The outlet is inserted into the skin to a depth of between 0.3 mm and 2 mm such that the delivery of the substance occurs at a depth between 0.3 mm and 2 mm. | 07-17-2014 |
20140207100 | HYBRID CANNULA AND METHODS FOR MANUFACTURING THE SAME - A hybrid cannula may comprise a first portion formed from a first material, a second portion formed from a second material overmolded to the first portion, a third portion formed from a third material and a fourth portion formed from a fourth material overmolded to the third material. The third portion is coupled to the first portion. The first portion may prevent the proximal end of the hybrid cannula from being pushed through a portal. The second portion may include a membrane and the fourth portion may include a dam, the dam defining interior spaces thereof between the proximal and distal ends of the hybrid cannula. The membrane and/or dam may prevent liquid from projecting during insertion or removal of instruments. The distal end of the hybrid cannula may comprise a variety of features. | 07-24-2014 |
20140207101 | MICROSTRUCTURE DEVICE WITH REMOVABLE MICROSTRUCTURE PATCH - A device and method for creating microchannels in the stratum corneum. The device includes a handle and a substrate detachably attached to the handle by a coupler. The substrate has a plurality of microstructures for creating microchannels in the stratum corneum. The substrate is detachable from the handle for disposal. | 07-24-2014 |
20140207102 | MEDICAMENT DISPENSING DEVICE - A portable medicament dispensing device having a mechanism which is not susceptible in jamming for dispensing the medication to a user. The device employs employs a coupling for coupling the relative motion between reciprocating body members housing the ancillary components and a barrel plunger associated with the syringe. One embodiment provides a pivoting coupling whereas an alternate uses a rack and pinion system. The advantage of simplifying such mechanisms results in a structure which has smooth unemcumbered motion with fewer parts to avoid mechanical jamming during use. | 07-24-2014 |
20140207103 | HAND-HELD ADIPOSE PROCESSOR AND CELL CONCENTRATOR - Devices and methods are provided for processing adipose tissue with a hand-held device. This device may include a processing chamber, a cannula, a vacuum source, a digestion area, and a product cell concentration chamber. | 07-24-2014 |
20140207104 | FLUID DISPENSER - A fluid dispensing device is provided for dispensing a measured amount of fluid into a living organism. The device has a needle having a first end and a second end. The needle is adapted for interfacing, on the first end, with a septum of a flexible hollow membrane, and at a second end thereof, for subcutaneously inserting into a living organism. The needle is guided by a guide to permit an injection into the living organism at a substantially non-orthogonal angle with respect to a surface of the living organism. The first and second ends of the needle pierce their respective piercing surface while translating together in a common direction. In other embodiments, the dispensing device includes a main housing, a flexible fluid reservoir, an injection assembly and a trigger mechanism. The main housing houses the operative components of the device. | 07-24-2014 |
20140207105 | Methods for Effectively and Rapidly Desensitizing Allergic Patients - Methods and compositions for delivering antigens to the lymphatic system in doses that desensitize patients to future exposure to antigens have been developed. Rapid desensitization is achieved by introducing small quantities of antigen into the lymphatic system. In preferred embodiments, the compositions are administered to yield therapeutically effective levels of antigen within the lymph, where macrophages reside in the greatest concentration, by intradermal administration, using for example, microneedles or microparticles, oral administration, using for example, enteric coated capsules or tablets, or autologous transfusion. In some embodiments, the methods and compositions for delivering antigens orally achieve uptake by the Peyer's patches of the small intestines. | 07-24-2014 |
20140207106 | AN AUTO INJECTOR WITH SEPERATE NEEDLE INJECTION - An auto injector having sequential control of needle insertion and dose injection is disclosed. A syringe with a needle is movably positioned in a housing between a first position in which the needle is accommodated inside the housing and a second position in which the needle protrudes outside the housing. A plunger rod tube has at least one locking member configured to normally lock a plunger rod to the plunger rod tube. A syringe driver applies a force to the syringe to move the syringe together with plunger rod tube, plunger rod and plunger rod driver from the first position to the second position. In the second position, the locking member is unlocked and releases the plunger rod to thereby activate the plunger rod driver to advance the plunger rod in the syringe for delivering of at least one dose of medicament. | 07-24-2014 |
20140213999 | Biological Chamber Interbody Spinal Fusion - Embodiments of the current invention provide minimally invasive methods for interbody fusion. In one aspect, the invention relates to a method of treating a patient that includes the steps of introducing a channel-forming instrument into a first vertebra, forming a channel through an endplate of the first vertebra and into a nucleus of an adjacent intervertebral disc without penetrating an annulus of the disc, and supplying a therapeutic agent to the nucleus of the disc via the channel. | 07-31-2014 |
20140214000 | Device for Moving a Piston Inside a Cartridge - A device for moving a piston inside a cartridge having a cartridge body and the piston displaceable along a longitudinal axis of the cartridge body is presented. The device comprises a first portion having first coupler for coupling the cartridge body to the first portion such that in both directions of the longitudinal axis, a connection exists between the cartridge body and the first portion; and a second portion having second coupler for coupling the piston to the second portion such that in both directions of the longitudinal axis, a connection exists between the piston and the second portion. The first and second portions move relative to each other to effect at least a forward displacement of the piston coupled to the second portion inside the cartridge body coupled to the first portion along the longitudinal axis. The second coupler establishes and releases the connection with the piston. | 07-31-2014 |
20140214001 | FLUID DISPENSING DEVICE - A device for delivering fluid, comprising an elongated outer casing ( | 07-31-2014 |
20140221967 | STEERABLE NEEDLE ASSEMBLY FOR USE IN VERTEBRAL BODY AUGMENTATION - Disclosed herein are devices for minimally invasive vertebral augmentation and restoration of spinal lordosis using a steerable cannula assembly. When deployed, the articulating cannula, including an outer cannula and an inner cannula extending into a central lumen of the outer cannula and coupled to each other at their distal ends, can be manipulated to curve/bend the body of the articulating cannula. This manipulation is used to create a void within the interior body and may also be used to control delivery of a treatment element to the interior body. | 08-07-2014 |
20140221968 | DEVICES AND METHODS FOR IMPROVED VASCULAR ACCESS - Devices and methods of use for obtaining and maintaining vascular access for the insertion of diagnostic or therapeutic drugs or devices into a patient. A device may include a first conduit extending along a longitudinal axis between a first end and a second end, the first end configured for coupling to a needle and the second end configured for coupling to a syringe. The device also includes a second conduit oblique to the first conduit and in communication with the first conduit. And the device includes a valve in communication with the second conduit, the valve being operatable between a closed position and an open position, wherein the open position is configured to provide access to the second conduit, such that an object may be introduced through the valve and second conduit into the first conduit and out the needle. | 08-07-2014 |
20140221969 | Endoscopic Injection Needle Device - An endoscopic injection needle device includes a flexible elongate sheath attached to a handle. Disposed within the sheath is drive shaft having a lumen within and a needle at its distal end. The drive shaft is movable longitudinally within the sheath and is attached at its proximal end within the handle to an actuator. Advancing the actuator extends the needle from the distal end of the device. The actuator includes a locking mechanism that locks it in place with the handle when advanced a certain distance. The locking mechanism includes multiple locking positions wherein the exposed length of the needle corresponds to the distance advanced by the actuator at each locking position. Also included in the distal end of the sheath are a spring coil and a collar. The collar is positioned distal to the spring coil and includes a dome shaped distal end that extends beyond the distal end of the sheath. The drive shaft extends through the spring coil and, when retracted, the needle is housed within the collar. The spring coil and collar stabilize the distal end of the sheath, facilitating consistent deployment and retraction of the needle. | 08-07-2014 |
20140221970 | SYSTEMS AND METHODS FOR PERFORMING AN INJECTION - Devices, systems, and methods for performing injections with lowered likelihood of infection include needles and other injection means with protective sleeves or sheaths. The protective sleeve can protect the needle before, during, or before and during an injection. The force needed to administer an injection or penetrate an insertion site using an injection device or system with a protective sleeve can be about the same to up to 50% more than the force needed for a system or device without a protective sleeve. The force needed to collapse the protective sleeve can be less than 100 gram-force. The material, the thickness, or both the material and the thickness of the protective sleeve may differ when comparing the portion of the sleeve near the needle tip and the portion near the base of the needle. | 08-07-2014 |
20140221971 | INJECTOR FOR AUTO-INJECTION OF MEDICATION AND ASSOCIATED METHOD OF USE - A key-shaped portable injector for delivering a dose of medication, the injector preferably including a cap, a body having an internal cavity, a syringe or cartridge with an attached needle within the internal cavity, a protective sleeve, an activation mechanism and a safety mechanism wherein the injector is reconfigurable from a first, non-deployed configuration where the activation mechanism, syringe or cartridge and a safety mechanism are all in a first position with respect to the body to a second, deployed configuration where the safety mechanism, activation mechanism, and syringe or cartridge are all in a second position with respect to the body and to a third, depleted configuration where the activation mechanism is back to its first position and a protective sleeve is in its second position. | 08-07-2014 |
20140221972 | METHOD FOR TREATING GLAUCOMA - A method of treating glaucoma or other eye disease in a patient is provided. The method includes injecting an eye of the patient with a cohesive monophasic gel containing cross-linked hyaluronic acid or its salt. The injection can be under the scleral flap and/or conjunctiva of the eye, thereby creating and maintaining a conjunctival bleb, and/or the injection can be in the supra-scleral and/or supra-choroidal (sub-scleral) space of the eye thereby reducing the intraocular pressure. | 08-07-2014 |
20140221973 | INTRAVENOUS PISTON PUMP DISPOSABLE AND MECHANISM - An apparatus for delivery of fluids to a patient includes an inlet tube and an outlet tube connected to each other at an angular joint. A rotary valve and a piston are fitted to the angular joint forming a chamber. The rotary valve is provided with a priming channel notch and a pumping notch. For priming operation with the fluid delivery apparatus, a user sets the rotary valve to a priming position. During pumping operation, the rotary valve rotates in coordination with the piston to transfer a quantum of fluid from the inlet tube to the outlet tube via the chamber. A second piston is optionally provided on the outlet tube for smoothing out flow rate pulsations. | 08-07-2014 |
20140221974 | RE-LOADABLE AUTO INJECTOR - A reloadable auto injector wherein a syringe assembly is movably positioned between a first position in which the needle is accommodated inside a housing and a second position in which the needle protrudes outside the housing. The assembly comprises a syringe, a plunger rod and a plunger rod driver configured to apply a force to the plunger rod to advance the plunger rod in the syringe for delivering at least one dose of medicament. A syringe driver is configured to apply a force to the assembly thereby moving the assembly from the first position to the second position. A reload handle may be connected to the assembly so that user operation of the reload handle retracts the assembly to the first position and simultaneously reload the syringe driver to thereby ready the auto injector for delivering a further dose of medicament. The plunger rod driver is not re-activated. | 08-07-2014 |
20140236119 | Method for Processing Infusion Data and an Infusion Pump System - A distributed infusion pump system is provided with long-term recording of the type of medication, nutrition or hydration, pump output pressure, corresponding infusion flow, infusion flow resistance, and an automatic or manual alarm in the event that thresholds applied to these parameters or their derivatives are exceeded. | 08-21-2014 |
20140236120 | ADJUSTABLE STIFFNESS CATHETER - The present invention relates to a catheter that has adjustable stiffness that enables a user to select the stiffness of at least one region of the catheter during insertion and navigation through a body lumen. A preferred embodiment of the invention works in combination with a guidewire to enable placement of the catheter at a position within the vascular system, for example, to enable treatment of a variety of medical conditions. The catheter can include segments that undergo relative movement in response to actuation by the user to adjust the flexibility of the at least one region, preferably located at or near the distal end of the catheter. | 08-21-2014 |
20140243783 | METHOD OF BACKFLOW REDUCTION DURING MATERIAL DELIVERY THROUGH A NEEDLE INTO TISSUE - Interstitial tissue structure is treated with a flowable liquid agent by: providing a delivery cannula having a proximal end and a distal end and an external surface with at least one expandable member located on the external surface of at least one catheter or needle. The delivery cannula is inserted into live tissue, creating a hole in the tissue surrounding the delivery cannula. Contact is made against an inner surface of the hole with contact pressure from the at least one expandable member, said contact pressure establishing a first level of stress in tissue surrounding the hole in the tissue. The expandable member is expanded to increase the contact pressure and provide a second level of stress in the tissue surrounding the hole in the tissue to a second level of stress that is greater than the first level of stress. | 08-28-2014 |
20140243784 | Medication Delivery Device - The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device. | 08-28-2014 |
20140243785 | Extensible Internal Bolster for a Medical Device - An internal bolster for use securing a medical device, such as a feeding tube, within a body of a patient is disclosed. In one embodiment, a feeding tube includes an internal bolster, comprising one or more bolster arms that each include a first end hingedly connected to a distal end of the medical device and a free second end. The bolster arms are selectively deployable between a first position wherein the bolster arms are substantially in-line with an axis of feeding tube, and a second position wherein the bolster arms are substantially deflected from the axis of the feeding tube to enable securement of the feeding tube within a stoma or other opening defined in the body. Various means for selectively moving the bolster arms between the first and second positions are disclosed. Related methods of use are also disclosed. | 08-28-2014 |
20140243786 | DELIVERY SYSTEM FOR HOLLOW MICRONEEDLE ARRAYS - The present disclosure relates to systems and methods for delivering microneedles to a patient's skin. In one aspect, the present disclosure provides a system for delivering a microneedle array to a patient's skin surface, the system comprising: a delivery apparatus including a housing; and an infusion device detachably received in the housing. | 08-28-2014 |
20140243787 | PHARMACEUTICAL INJECTION DEVICE, METHOD FOR CONTROLLING PHARMACEUTICAL INJECTION DEVICE, AND RECORDING MEDIUM - A pharmaceutical injection device comprises a main body case ( | 08-28-2014 |
20140243788 | TRANSDERMAL ADHESIVE PATCH ASSEMBLY WITH REMOVABLE MICRONEEDLE ARRAY AND METHOD OF USING SAME - A transdermal adhesive patch assembly and method of using same. The assembly can include a backing, and an adhesive and a matrix coupled to the backing. The matrix can include an active ingredient. The assembly can further include a microneedle array in at least partially overlapping relationship with the matrix; and a carrier that couples the microneedle array to the matrix opposite the backing, wherein the carrier and the microneedle array form a skin treatment assembly that, along with the matrix, can be located on a flap. The method can include adhering at least a portion of the adhesive to skin to form an anchor; applying pressure adjacent the microneedle array to treat an area of the skin; moving the flap away from the skin; removing the skin treatment assembly to expose the matrix; and replacing the flap to position the matrix over the treated area of the skin. | 08-28-2014 |
20140249501 | System and Method for Injection Protocol Management - A fluid injection system for controlling at least one fluid delivery system is provided. The fluid injection system includes at least one computing device in communication with the at least one fluid delivery system. The at least one computing device is configured to: display, on or with at least one display device, at least one graphical user interface configured to facilitate a user selection of at least one injection protocol of a plurality of injection protocols; receive, from at least one user, at least one selected injection protocol from the plurality of injection protocols; retrieve, from at least one remote server computer, the at least one selected injection protocol; and control the at least one fluid delivery system based at least partially on the at least one selected injection protocol. | 09-04-2014 |
20140249502 | Single Step Removal of Cannula Guard and Adhesive Liner in Medical Device - A medical device includes a body and a cannula extending from the body, for insertion into a patient's skin. The medical device also includes a guard covering the cannula, an adhesive for securing the medical device to the patient's skin, and an adhesive liner covering the adhesive. The guard is connected to the adhesive liner to enable conjoint and at least partial removal of the guard and the adhesive liner. | 09-04-2014 |
20140249503 | INTRAVENOUS FLUID MONITORING - Apparatus, systems and methods related to monitoring intravenous fluids during administration to a subject are disclosed. These apparatus, systems and methods provide near real-time monitoring of the identity of one or more components of an intravenous fluid. | 09-04-2014 |
20140257239 | BONE FRACTURE REDUCTION SYSTEM AND METHODS OF USING THE SAME - A method of treating a fracture includes creating an access path to a fracture site in a bone and inserting a guidewire through the access path into the fracture site is provided. The method includes the steps of positioning a cannulated drill bit having a distal end including helical flutes configured for drilling through bone over the guidewire into the fracture site, and advancing the drill bit to create a passageway in the bone configured to receive a screw. Positioning a cannulated inflatable bone tamp over the guidewire and inflating the inflatable bone tamp to compress at least a portion of the bone in or near the fracture site so as to create a void. Delivering a bone void filler into the void through the access path to fill the void. Systems and kits are disclosed. | 09-11-2014 |
20140257240 | ARTICULABLE INTRODUCER SHEATH - Articulable introducer sheaths and related methods and systems for accessing various surgical sites are disclosed. An introducer sheath comprises a tubular body and a filament. The tubular body has a proximal portion, a distal portion, and a central lumen. The filament is constrained on or within at least a portion of the proximal portion and unconstrained over at least a portion of the distal portion. The distal end of the filament is held or attached near a distal end of the tubular body so that advancement of the filament relative to the tubular body causes the unconstrained portion to bow out or extend radially outward, such as to engage a body tissue so as to steer the tubular body when the tubular body has been introduced into a surgical site, such as an epidural space. A surgical tool or medical implant can then be advanced through the sheath. | 09-11-2014 |
20140257241 | HANDHELD MEDICAL SUBSTANCE DISPENSING SYSTEM, APPARATUS AND METHODS - Various handheld medical dispensing configurations and methods including the following: Handheld medical dispensing system comprises a syringe, which has a plunger, releasably mounted to syringe actuation apparatus, the apparatus having an actuator configured such that it can move the plunger more than once to dispense a plurality of amounts of substance from the syringe. A method of dispensing fluid from a syringe comprises holding a medical substance delivery system including a syringe, which has a needle, and which is secured to syringe actuation apparatus configured to dispense predetermined amounts of the substance from the syringe, penetrating the needle at one patient site and using the apparatus to deliver a predetermined amount of the substance, and penetrating the needle at another patient site and using the apparatus to deliver a predetermined amount of the substance. | 09-11-2014 |
20140276559 | DEVICES, SYSTEMS AND METHODS FOR PLACEMENT OF INSTRUMENTS FOR MEDICAL PROCEDURES - Medical guide devices, systems and methods are provided, comprising a base member and a rotatable medical guide component seated on the base member. The guide component defines a path extending through the guide component. The guide component includes a first radio-opaque marker located at a first end of the guide component corresponding with an entry point of the path and a second radio-opaque marker located at a second end of the guide component corresponding with an exit point of the path, and the second end is opposite the first end. | 09-18-2014 |
20140276560 | Infusion Management Platform For Medication Container Volume Tracking - An infusion management platform specifies, for each of a plurality of containers, an identification for one of a plurality of patients, an identification for an infusion module, and attributes characterizing fluid within the container for infusion into the corresponding patient. Thereafter, the infusion management platform receives data from a plurality of infusion modules characterizing administration of fluid to each of a plurality of patients. It can then be determined by the infusion management platform for each container using a rule set, an amount of the fluid infused to the corresponding patient and an amount of fluid remaining in the container. Data can then be provided that characterizes the determined amount of infused fluid and the determined amount of remaining fluid for each container. Related apparatus, systems, techniques and articles are also described. | 09-18-2014 |
20140276561 | DEVICE FOR PERFORMING A SURGICAL PROCEDURE AND METHOD - A device including a first member extending along an axis. The first member includes an inner surface defining a cavity extending through a first surface and an opposite second surface and a side surface extending between the first and second surfaces. The inner surface defines an opening extending that is in communication with the cavity. A pivoting member is disposed in the cavity and includes an inner surface defining a passageway having a second member disposed therein. An engaging member is disposed in the opening. The pivoting member is movable between a first orientation such that the engaging member is spaced apart from the pivoting member and the pivoting member is rotatable to a selected trajectory relative to the longitudinal axis and a second orientation such that the engaging member engages the pivoting member and the second member is fixed in the selected trajectory. Methods of use are disclosed. | 09-18-2014 |
20140276562 | CATHETER WITH SPRAY IRRIGATION - A medical probe, including a flexible insertion tube having a distal end for insertion into a body cavity, and a channel contained within the insertion tube and configured to convey a fluid to the distal end. A terminal member is fixed to the distal end of the insertion tube and includes a distal tip configured to be brought into contact with tissue in the body cavity, the distal tip having a first diameter, and a protruding shoulder surrounding the distal tip and having a second diameter, which is greater than the first diameter. The distal tip has one or more spray ports passing through the shoulder which are coupled to the channel so as to direct the fluid from the shoulder toward the tissue so as to irrigate the tissue. | 09-18-2014 |
20140276563 | Angled Inserter For Drug Infusion - An infusion set adapted to be secured to a skin surface includes a fixed base member and a movable slide member. The fixed base member is connectable to the skin surface. The movable slide member has a needle or cannula connected thereto and is movable relative to the fixed base member. The movable slide member is movable from a first position in which the needle or cannula is not exposed externally of the fixed base member to a second position in which the needle or cannula is exposed externally of the fixed base member. A hub is fixedly connected to the movable member and has a slot extending rearwardly in a lower surface from a first end thereof. The needle or cannula is received in the slot. The movable slide member is locked to the fixed base member in the second position. | 09-18-2014 |
20140276564 | PUMP CONTROLLER AND PUMP FOR INDIVIDUALIZED HEALTHCARE USE - According to an aspect of the present disclosure, a pump system for individualized healthcare use includes an infusion pump, a display, an input interface, and a pump controller. The pump controller is associated with a memory in which a closed set of predefined infusion therapies and a personalized identifier associated with an individual patient are stored. The pump controller is programmed to display the personalized identifier; to operate according to a first operational state, wherein the pump controller receives an input via the input interface, selects a predefined infusion therapy according to the input received, and controls the infusion pump to provide the selected predefined infusion therapy; to operate according to a second operational state; and to receive an operational state code via the input interface, and to change from the first to the second operational state only when the operational state code is received. | 09-18-2014 |
20140276565 | Infusion Channel Identifiers - The current subject matter describes generation and use of infusion channel identifiers that identify infusion channels transporting medication from an infusion pump to a patient. The infusion pump includes a user interface device, a controller, and at least one infusion device. At a first user interface of the user interface device, data associated with an infusion channel is received. Based on the data, the controller generates an infusion channel identifier identifying the infusion channel. On the first user interface, the infusion channel identifier is displayed. At a second user interface of the user interface device, the infusion channel identifier, a beginning time of a desired provision of the medication to the patient, and a time duration of the desired provision is received. The controller actuates the infusion device and the infusion channel at the beginning time for the time duration. The infusion device delivers, via the infusion channel, the medication to the patient. Related apparatus, systems, techniques and articles are also described. | 09-18-2014 |
20140276566 | INFUSION TUBING TRACING SYSTEM USING VIBRATION GENERATOR AND VIBRATION SENSOR - A system for tracing tubing which forms a conduit from a source of infusion liquid to a patient by way of an infusion pump has a vibration generator manually operable by a user to generate vibrations at an origin location along the tubing, wherein the vibrations are propagated by the tubing and have a vibration signature. A vibration sensor arranged at a destination location along the tubing receives the vibrations and generates a digital vibration signal. Signal processing circuitry connected to the vibration sensor processes and evaluates the digital vibration signal to determine a trace status of the tubing between the vibration generator and the vibration sensor. An indicator connected to the signal processing circuitry provides an indication of the determined trace status. Trace status possibilities include clear, cross-over, and null. A likely number of cross-overs may also be indicated. | 09-18-2014 |
20140276567 | Device and System for Dispensing a Biological Sealant - A system and method for delivery of a biological material using a gas-assisted delivery, including a gas entry port at the proximal end of the delivery system, particularly useful for the delivery of a two-part biological component. | 09-18-2014 |
20140276568 | SYSTEMS AND METHODS FOR DAMPENING FRICTION IN AN AUTOINJECTOR DEVICE - Systems, devices, and methods are described for using an autoinjector device. In one aspect, an autoinjector device comprises a housing and a plunger slidably mounted to the housing, the plunger including a tapered region. An actuator urges the plunger with respect to the housing from a storage position to a launch position, and a friction element about a portion of the tapered region resists a movement of the plunger from the storage position to the launch position. | 09-18-2014 |
20140276569 | SYSTEM AND METHOD FOR DETECTING PRESENCE OF AN INFUSION CARTRIDGE IN AN INFUSION PUMP - Infusion devices, systems, and methods can detect a presence or absence of an infusion cartridge in an infusion pump. Embodiments may include a loading sequence, recording loading pulse width modulation (PWM) commands applied to an infusion pump motor during the loading sequence, setting a value of threshold PWM commands based on the commands applied during the loading sequence and comparing values of operational PWM commands applied during pumping operations to the value of the threshold PWM commands. If the value of the operational PWM commands drops below the threshold by a predetermined amount, a missing infusion cartridge warning may be generated. | 09-18-2014 |
20140276570 | GRADUAL TRANSITION BETWEEN BASAL RATES IN AN AMBULATORY DRUG DELIVERY DEVICE - A controller in an ambulatory drug delivery device automatically creates gradual transitions between basal rates entered by a user. The user may enter at least two target basal rates and two corresponding durations for delivering a medication at each rate. Systems and methods for such drug delivery are described. | 09-18-2014 |
20140276571 | FIELD UPDATE OF AN AMBULATORY INFUSION PUMP SYSTEM - Portable or ambulatory infusion devices and systems capable of remotely updating an ambulatory fluid delivery device include safety protocols that verify the status of the ambulatory fluid delivery device before and after a field update of software. Methods of accomplishing the same field update of software are also described. | 09-18-2014 |
20140276572 | DEVICE FOR PERFORMING A SURGICAL PROCEDURE AND METHOD - A medical balloon device includes an outer member extending along an axis. An inflatable member has a proximal end extending from a first end of the outer member and a distal end. An inner member is positioned within the outer member and the inflatable member such that a first end of the inner member is coupled to the distal end of the inflatable member. A support member is movably disposed within the inner member and includes a first end configured to removably engage the first end of the inner member. Translation of the support member along the axis causes the inflatable member to move between a first position in which the inflatable member has a first length and a first profile and a second position in which the inflatable member has a second reduced length and a second reduced profile. Methods of use are disclosed. | 09-18-2014 |
20140276573 | Filling Methods and Apparatus for Implanted Medical Therapy Delivery Devices - Transdermal insertion of a transcutaneous filling apparatus, for the purpose of filling a fill chamber of an implanted therapy delivery device, is monitored by measuring each impedance between pairs of electrodes of a needle of the apparatus, and comparing each to a threshold impedance; the electrodes, preferably at least three in number, are isolated and spaced apart from one another along a length of the needle. A confirmation signal is generated when at least one of the measured impedances is greater than the threshold impedance, and another is less than the threshold, the condition indicating that one of the electrodes is located within a non-conductive septum, through which the apparatus must pass to access the fill chamber. A detection circuit, which may be located in a housing of the apparatus that is attached to a proximal end of the needle, measures and compares the impedances. | 09-18-2014 |
20140276574 | METHOD AND DEVICE UTILIZING INSULIN DELIVERY PROTOCOLS - A method of infusing liquid medicaments including insulin via an insulin pump, includes identifying an insulin delivery protocol associated with ingestion of carbohydrates wherein the insulin delivery protocol is likely to lead to a postprandial drop in blood glucose to a level below a basal level, then proposing at least one alternative insulin delivery protocol to inhibit the postprandial drop in blood glucose by delivering a metered amount of insulin that is appropriate to facilitate the metabolism of the carbohydrates without the postprandial blood glucose level drop. The invention further includes querying the patient as to whether to apply the alternative insulin delivery protocol, receiving instructions from the patient in response to the query, and applying the alternative insulin delivery protocol following receiving instructions from the patient to apply the alternative insulin delivery protocol. | 09-18-2014 |
20140276575 | SYSTEM AND METHOD FOR VERIFYING ALIGNMENT OF DRUG PUMP AND FLUID SUPPLY - A patient care system is configured for infusing fluid to a patient. The system includes a plurality of fluid infusion pumps, each of which is connected to a respective fluid supply for pumping the contents of a fluid supply to a patient via fluid supply lines. The system includes a pressure sensor downstream of the fluid infusion pumps for determining if a particular fluid is connected to a designated infusion pump. | 09-18-2014 |
20140276576 | Automatic Angled Infusion Set Assembly - An infusion set adapted to be secured to a skin surface includes a fixed base member connectable to the skin surface and a movable member. A needle or cannula is connected to the movable member and movable relative to the fixed base member. The movable member is movable from a first position in which the needle or cannula is not exposed externally of the fixed base member to a second position in which the needle or cannula is exposed externally of the fixed base member. A release member retains the movable member in the first position. Removal of the release member allows movement of the movable slide member to the second position. | 09-18-2014 |
20140276577 | Thermochemical Reaction Ablation Catheter - Embodiments disclosed herein are directed to devices, methods, and systems for the treatment of tissue using energy delivery. Specifically, certain embodiments may utilize a thermochemical reaction between at least two reagents where a first reagent has been preloaded into a catheter while a limiting reagent is circulated through the catheter to react with the first reagent. The resulting chemical reaction may be exothermic or endothermic, and a heat transfer fluid may be used to exchange energy between the chemical reaction and surrounding tissue. | 09-18-2014 |
20140276578 | METHODS AND APPARATUS FOR SELECTIVELY OCCLUDING THE LUMEN OF A NEEDLE - A fluid transfer device for parenterally transferring fluid to and/or from a patient includes a housing, a needle, and an occlusion mechanism. The housing defines a fluid flow path and is couplable to a fluid reservoir. The needle has a distal end portion that is configured to be inserted into the patient and a proximal end portion that is configured to be fluidically coupled to the fluid flow path of the housing, and defines a lumen therebetween. The occlusion mechanism selectively controls a fluid flow between the needle and the fluid flow path. The occlusion mechanism includes an occlusion member that is movable between a first configuration where the lumen of the needle is obstructed during insertion into the patient and a second configuration where the lumen of the needle is unobstructed after the needle has been inserted into the patient allowing fluid transfer to or from the patient. | 09-18-2014 |
20140276579 | DEVICES AND METHODS FOR SECURING AN ANTI-LEAK FEEDING TUBE FOR GASTRIC AND/OR INTESTINAL USE - Medical device designs for enteral nutrition that inhibit the relative motion of one device member to another device member are herein disclosed. The gastric and/or intestinal feeding tube shaft is disposed of teeth, furrows, ridges, indentions, tabs, or corrugations that operate with an external retaining member. Alternative embodiments utilize an external retaining member with a collet fitting that applies pressure against the gastric and/or intestinal feeding tube shaft. The assemblies prevent the relative motion of the internal retention member relative to the external retaining member and assist in maintaining the internal retention member against the gastric wall. | 09-18-2014 |
20140276580 | MICROPROJECTION APPLICATORS AND METHODS OF USE - Applicators for a microprojection array and methods of using the applicators are described. | 09-18-2014 |
20140276581 | ASSEMBLY FOR DISPENSING BIOMATERIAL, PLUNGER THEREFOR, AND RELATED METHODS - An assembly includes a dispensing syringe device configured to receive an amount of biomaterial and to dispense the biomaterial. The dispensing syringe device includes a syringe barrel for receiving the biomaterial, a discharge outlet for dispensing the biomaterial from the syringe barrel, and a plunger received in the syringe barrel. The plunger has a plunger body and a plunger passageway extending therethrough configured to receive a stylet. The assembly further includes a cannulus device configured to be coupled with the dispensing syringe device, to receive biomaterial from the dispensing syringe device, and to dispense the biomaterial. The cannulus device includes a cannulus passageway configured to receive the biomaterial and a dispensing opening configured for dispensing the biomaterial. | 09-18-2014 |
20140276582 | SUBSTANCE DELIVERY DEVICES, SYSTEMS AND METHODS - A substance delivery device includes an elongated tubular body having opposing proximal and distal ends, and a diaphragm that is in slideable sealing engagement with an inside wall of the tubular body. The diaphragm is movable in opposite first and second directions within the tubular body. A substance is contained within the tubular body between the diaphragm and the tubular body distal end, and a slave fluid is contained within the tubular body between the diaphragm and the tubular body proximal end. When pressure is exerted on the slave fluid, the slave fluid causes the diaphragm to move and eject the substance through the tubular body distal end. | 09-18-2014 |
20140276583 | INJECTION DEVICE WITH AUTOMATIC DATA CAPTURE AND TRANSMISSION - An injection device, which can be, e.g., an insulin pen, can capture and transmit injection and/or medicament information to another device, such as, e.g., a blood glucose meter. The injection and medicament information can include, e.g., time and date of injection, type of medicament injected, and dosage amount. The injection device can include a dial cap that can be rotated to select a dosage amount to be injected. In some embodiments, the dial cap can include a microcontroller with transmitter, a Hall effect sensor, and a ring magnet. In some embodiments, the injection device can include a medicament cartridge with a 1-wire EEPROM, which can have medicament information stored therein. Methods of operating an injection device are also provided, as are other aspects. | 09-18-2014 |
20140276584 | DILATING CANNULA WITH RADIALLY EXPANDABLE FLANGE AND METHOD OF USING THE SAME - A dilating cannula includes a radially expandable flange and an expandable shaft. The radially expandable flange is disposed at a proximal end portion of the dilating cannula and includes two or more sectors that are each independently movable. The expandable shaft extends from the proximal end portion to a distal end portion of the dilating cannula and defines an inner passageway of the dilating cannula and includes two or more arms. A first branch of the two or more arms extends from one end of the base section and a second branch of the two or more arms extends from another end of the base section. The first branch is connected to a first sector of the two or more sectors of the radially expandable flange and the second branch is connected to a second, different sector of the two or more sectors of the radially expandable flange. | 09-18-2014 |
20140276585 | LENGTH ADJUSTABLE BALLOON CATHETER FOR MULTIPLE INDICATIONS - Adjustable balloon catheter including an inner tubular member that has an inflation lumen. An expandable member is coupled to the distal end portion of the inner tubular member and has an inner chamber in fluid communication with the inflation lumen. The expandable member is transitionable between a deflated and an inflated configuration. The expandable member defines has a non-cylindrical shape including a first section having a first diameter in the inflated configuration and a second section having a second diameter when in the inflated configuration. The first diameter is different than the second diameter. An outer tubular member is movable relative to the inner tubular member. The outer tubular member is moveable between an extended position disposed over the expandable member and a fully retracted position proximal to the extended position. The outer tubular member is selectively positioned between the extended position and the fully retracted position. | 09-18-2014 |
20140276586 | STEERABLE SURGICAL NEEDLE - A steerable surgical needle ( | 09-18-2014 |
20140276587 | Infusion System for the Controlled Delivery of Therapeutic Agents - Embodiments of the invention provide infusion systems for the intravenous or other delivery of drugs and other therapeutic agents to a patient including a human or mammal. The therapeutic agents may be dissolved in solution or comprise the solution itself. Embodiments of the systems can utilize a chemical reaction to predictably drive a flow of drug(s) through a catheter or other flow path and into the patient. More specifically, the reaction may include an acid-base reaction or any other reaction that produces a gaseous substance. The gas is produced and contained in an expandable drive balloon when the acid-base reactants are combined with a liquid. As the gas is produced, the drive balloon expands to exert pressure on a separately-contained drug reservoir which, in turn, pushes drug(s) from the reservoir into the flow path where the drug is ultimately delivered to the patient in a controlled and predetermined manner. | 09-18-2014 |
20140276588 | INJECTION DEVICES WITH CONTROLLABLE DEPTH ADJUSTABILITY AND METHODS OF USE - An injection device for injecting a material into tissue may include a sheath having a distal end. The injection device may also include an injector having an outlet tube. The outlet tube may be received in the sheath, and may include a distal portion with a penetrating tip for penetrating the tissue. The sheath and the outlet tube may be slidable relative to each other, to extend a length of the distal portion from the distal end. The injection device may also include an adjuster operatively coupled to at least one of the sheath and the outlet tube. The adjuster may be configured to control relative movement between the sheath and the outlet tube for selectively adjusting the extended length. | 09-18-2014 |
20140276589 | MICROARRAY FOR DELIVERY OF THERAPEUTIC AGENT AND METHODS OF USE - Microstructure arrays and methods for using and manufacturing the arrays are described. | 09-18-2014 |
20140276590 | DELIVERY DEVICES AND RELATED METHODS OF USE - According to an aspect of the disclosure, a treatment method may include treating a wall of a portion of a gastrointestinal tract of a patient. Treating the wall may include positioning one or more injection units adjacent to the wall. Treating the wall may also include affecting at least one of movement of gastrointestinal tract contents through the gastrointestinal tract and absorption of gastrointestinal tract contents by the gastrointestinal tract, by injecting material into the wall using the one or more injection units. Injecting the material may include injecting the material between layers forming at least a portion of the wall. | 09-18-2014 |
20140276591 | PERCUTANEOUS INTERVERTEBRAL ANNULAR REGENERATION - A regeneration device and method for sealing annular tears between the nucleus pulposus and the annulus fibrosus of an intervertebral disc. The regeneration device includes a trocar having a sharp tip at a distal end, an inner cavity, and a handle portion attached to a proximal end of the trocar. The device further includes a plunger coupled to a catheter that extends through the inner cavity. The regeneration method includes inserting the trocar into an intervertebral disc via Kambin's triangle, and once the trocar reaches the nucleus pulposus, the catheter is extended alongside the annulus fibrosus wall to surround the nucleus pulposus. A syringe is mounted to the plunger and injects a biochemical, biological and/or synthetic material through multiple ports in the catheter to form a collagen barrier that prevents the nucleus pulposus from protruding through the annulus fibrosus. | 09-18-2014 |
20140276592 | LOCKABLE SYRINGE ASSEMBLIES AND RELATED DEVICES AND METHODS - The embodiments disclosed herein relate to lockable syringe assemblies and related devices and methods. The syringe assembly may include a barrel, a plunger, and a locking mechanism. In some arrangements, the locking mechanism is an elastomeric locking ring or a rigid partial ring. The plunger may include a plurality of ribs and is longitudinally moveable within the barrel. Once the plunger is disposed at a desired longitudinal location, the plunger can be axially rotated and locked in such a way that further longitudinal movement is restricted. | 09-18-2014 |
20140276593 | METHODS AND SYSTEMS FOR TREATMENT OF A BLADDER - A medical device is disclosed. The medical device may include an elongate member having a proximal end and a distal end an expandable end effector assembly extending distally from the distal end of the elongate member. The end effector assembly may include a plurality of end effector units each having an injector for simultaneously delivering material into tissue. | 09-18-2014 |
20140276594 | CATHETER TENSION SENSING - This disclosure covers various concepts to use for obtaining measurement of tension in catheter pullwires to improve controllability of a robotic surgical system. | 09-18-2014 |
20140276595 | MULTI-STAGE BIODEGRADABLE DRUG DELIVERY PLATFORM - Embodiments of the invention provide multi-stage biodegradable drug delivery platforms and methods for the subcutaneous delivery of therapeutic agents (TA). Embodiments of the platform may be configured to subcutaneously deliver a first dose of a first TA which is absorbed into the body and/or blood stream (BBS) to produce a first therapeutic effect for a first selectable time period (STP), and subsequently after a second STP, deliver a second dose of a second TA which is absorbed into the BBS to produce a second therapeutic effect for a third STP. An embodiment of the platform may comprise a body having a tissue-penetrating end, a primary cavity having a first TA dose and a shell having a secondary cavity having a second TA dose. The first TA dose is released after the first STP and the second TA dose is released after the second STP by biodegradation of the shell. | 09-18-2014 |
20140276596 | CANNULATED SYRINGE - A set of instruments configured to deliver a therapy to a bone can include a cannulated syringe. The cannulated syringe can extend along a longitudinal axis between a proximal and a distal end. The cannulated syringe can have an inner tube and an outer tube that are interconnected at the distal end as a single fixed unit. A first cannulation can be formed along the longitudinal axis of the cannulated syringe within the inner tube and a second cannulation can be formed within an annular space between the inner and outer tubes. The outer tube can define an opening through a sidewall thereof. The cannulated syringe can be closed from fluid communication between the inner and outer tubes. | 09-18-2014 |
20140276597 | NASAL VENTILATION SYSTEM AND METHOD OF USING SAME - An apparatus for creating an accessory maxillary ostium for purposes of ventilation, irrigation, or procedural work within the maxillary antrum. An introducer having a ventilation tube and grommet is provided to create and then provide access through the accessory maxillary ostium. An irrigation catheter may be advanced through the ventilation tube in order to irrigate or express the contents of the sinus cavities. A secondary irrigation catheter or a balloon catheter may be advanced through an outer irrigation catheter, deeply into the sinus cavity, in order to irrigate or express the contents of the sinus cavities. Moreover, the balloon catheter may alternatively or additionally be employed to for dilation of the natural ostium. Still further, a device for delivering drugs, fluids or the like, may be coupled to the ventilation tube for delivery of same. | 09-18-2014 |
20140276598 | INJECTION DEVICE FOR DELIVERING A FIXED DOSE OF LIQUID DRUG - An injection device ( | 09-18-2014 |
20140288528 | SINGLE-USE NEEDLE ASSEMBLY AND METHOD - A needle assembly that has a flexible shield movable between (i) a first position, where the flexible shield is uncompressed, and (ii) a second position, where the flexible shield is compressed and an administering member located within the flexible shield, where at least one of the administering member and the flexible shield is axially movable with respect to the other of the administering member and the flexible shield in an unlocked position prior to and during usage of the needle assembly, and the at least one of the administering member and the flexible shield is no longer axially movable with respect to the other of the administering member and the flexible shield in a locked position. Prior, during and after use of the needle assembly, the needle is never exposed. After a single usage of the needle assembly, the needle is locked within the flexible shield and cannot be reused. | 09-25-2014 |
20140288529 | ROTATING LOCK RESET SYSTEM AND METHOD - A system and method for resetting a locking mechanism of a medicament delivery or training device is provided herein. The system and method include a central shaft comprising a slotted ring, a pronged ring, a spring, a spring clamp, an actuator button, and a lock ring. Following the firing of the medicament device, wherein the actuation member has been activated and the lock ring in the unlocked position, the system and method can be initiated to reset the locking mechanism such that the components of the system and the lock ring are reset to the locked position before the actuation member can be actuated for a subsequent injection or training. | 09-25-2014 |
20140288530 | SYSTEM AND METHOD FOR ADAPTABLE SAFETY SYRINGE - One embodiment is directed to a method of conducting an injection, comprising: providing an assembly of a syringe plunger movably coupled to a syringe body which may contain fluid for infusion, the syringe body having a distal end that is removably coupled to a Luer adaptor, the Luer adaptor defining a needle lumen through which a needle may be coupled, the Luer adaptor comprising a distal surface configured to be removably coupled to a Luer fitting of another device; deciding upon infusion via needle injection or Luer coupling; and selectably configuring the assembly for needle injection or Luer coupling by removing the Luer adaptor to further expose the needle for needle injection, or by leaving the Luer adaptor in place and coupling it to the Luer fitting of the other device. | 09-25-2014 |
20140296824 | APPARATUS AND METHODS FOR SELF-ADMINISTRATION OF VACCINES AND OTHER MEDICAMENTS - A medicament delivery device includes a housing, a medicament container disposed within the housing, an activation mechanism, a cover and an electronic circuit system. The activation mechanism includes an energy storage member configured to produce a force to deliver the dose of a medicament and/or vaccine. The cover is configured to receive at least a portion of the housing. The electronic circuit system is coupled to the housing such that a protrusion of the cover electrically isolates a battery from a portion of the electronic circuit system when the portion of the housing is received by the cover. The electronic circuit system is configured to be electrically coupled to the battery and to produce a recorded speech output when the portion of the housing is at least partially removed from the cover. The electronic circuit system configured to produce a signal when the activation mechanism is actuated. | 10-02-2014 |
20140296825 | METHOD AND DEVICE FOR INSERTING NEEDLES - The invention relates to a device for inserting needles, including a body defined by a proximal end and a distal end, a mounting movably mounted inside the body, at least one needle secured to the mounting, a drive means suitable for driving the mounting towards said distal end, said mounting comprising a distal surface onto which the needle projects, said distal end comprising a contact area intended for contacting the tissue, the mounting being configured so as to reach a position, after activating the driving means, in which the distal surface thereof, relative to said proximal end, is more distant than said contact area, wherein the device is further configured so as to enable a gradual passive return movement of the mounting once said position has been reached. | 10-02-2014 |
20140296826 | PREPARATION PATCH AND SAFETY SYRINGE SYSTEM - A safety syringe system including a safety syringe and an injection site preparation patch adapted for use with the safety syringe. The safety syringe includes a syringe body and a safety shield slidably disposed about the syringe body. The injection site preparation patch has a tissue-facing side and a syringe-facing side, and may include a substrate, a syringe adhesive layer adapted to adhere to a distal flange of the safety shield, a hydrogel layer adapted to adhere to tissue, and removable release liners disposed on either side. The patch may include a medicament, anesthetic, or a thermal compound. Adhesion between the patch and the flange is less than adhesion between the patch and tissue, so that the patch adheres to the shield with sufficient strength to enable the shield to slide over the needle upon withdrawal, but with insufficient strength to cause the patch to pull away from a patient's skin. | 10-02-2014 |
20140296827 | Medicine Delivery Device Having Detachable Pressure Sensing Unit - A fluid medicament delivery device includes a patient attachment unit and a separate indicator unit. The patient attachment unit includes a housing and a fluid channel located therein, wherein at least a portion of the fluid channel includes a flexible member substantially coterminous with the housing. The separate indicator unit is adapted to be detachably coupled to the housing of the patient attachment unit and includes a first sensing element for contacting the flexible member when the indicator unit is coupled to the housing to sense a flexure of the flexible member. | 10-02-2014 |
20140296828 | STYLET ASSEMBLIES, CATHETER KITS AND ASSEMBLIES INCLUDING STYLET ASSSEMBLIES, AND RELATED METHODS - Stylet assemblies include one or more securing members extending from a base portion of the stylet assembly and configured to removably attach to a portion of an associated structure. Catheter kits and catheter assemblies may include such stylet assemblies. Methods of using a catheter assembly may include inserting at least a portion of a stylet coupled to a stylet cap in a catheter associated with a catheter connection and securing a portion of the stylet cap to only a portion of the catheter connection hub. | 10-02-2014 |
20140303593 | DELIVERY OF MATERIALS INTO MARGINS OF TISSUE CAVITIES - Surgery is performed on a patient with a novel device by:
| 10-09-2014 |
20140303594 | FOLDABLE ADHESIVE COMPOSITE DRESSING - An adhesive composite dressing useful for applying an active ingredient to a treated skin site, as well as methods of manufacture and use of such dressings. In one embodiment, an adhesive composite dressing comprising an anchor member, a target member, and a folding member, where the anchor member comprises a first skin-contact adhesive, the target member comprises an opening adapted to enable skin treatment, the folding member comprises a drug reservoir, and where the folding member is attached to the anchor portion through a hinge defined by a line of attachment that is not contiguous with an edge of the anchor member. | 10-09-2014 |
20140309616 | SIMULATED MEDICAMENT DELIVERY DEVICE CONFIGURED TO PRODUCE AN AUDIBLE OUTPUT - An apparatus includes a simulated medicament delivery device and an electronic circuit system. The simulated medicament delivery device includes a housing, and is devoid of a medicament delivery mechanism that causes a medicament to be delivered. The electronic circuit system is coupled to the housing and includes an audible output device and a cover. The housing of the medicament delivery device and the cover of the electronic circuit system collectively define an acoustic enclosure. The audible output device is configured to be disposed within the acoustic enclosure. | 10-16-2014 |
20140309617 | FLUID FLOW MEASUREMENT AND CONTROL - In accordance with another embodiment, a controller in a fluid delivery system initiates drawing fluid into a chamber of a diaphragm pump. During a delivery phase of pumping the fluid in the chamber to a target recipient, the controller applies pressure to the chamber. At multiple different times during the delivery phase, the controller temporarily discontinues application of the pressure to the chamber to calculate how much of the fluid in the chamber has been pumped to the target recipient. | 10-16-2014 |
20140309618 | Safety Device Actuation System - The present disclosure relates to a safety needle assembly that includes a syringe and a safety mechanism. The safety mechanism includes a housing defining an internal cavity, a shield member at least partially disposed within the internal cavity, and first and second locking members that are configured to selectively engage and maintain the shield member in one or more predetermined positions. The locking members are movable between a locked position, in which the locking members are in engagement with the shield member to substantially prevent axial movement thereof, and a release position, in which the locking members are disengaged from the shield member to permit axial movement thereof. The first and second locking members each include biasing members. The biasing member of the each locking member is positioned to cooperate with the other locking member to normally bias the locking members towards the locked position. | 10-16-2014 |
20140309619 | MECHANICAL LEECH SYSTEM - A mechanical leech system may include a fluid exchange assembly. The fluid exchange assembly may be attached to a patient's target tissue area via suturing or the like, and may be activated to perform blood removal and treatment agent infusion. The fluid exchange assembly may include an inflow pathway for infusion of treatment agents into the tissue area, and an outflow pathway for removal of blood. The outflow pathway may be sized and/or shaped to promote laminar fluid flow and avoid coagulation. The assembly may include a channel housing, gasket, and base. Needles seated in the assembly may receive blood from a patient and infuse a treatment agent into the patient. The assembly may be connectable to a pump to urge the blood and the treatment agent through the inflow and outflow pathways. A cradle optionally provides protection and storage for the assembly. | 10-16-2014 |
20140309620 | TRANSILLUMINATING OBTURATOR - Methods and devices for placement of a medical device using illumination are disclosed. | 10-16-2014 |
20140316373 | Cerebrospinal Fluid Cooling Device - A device for topical cooling of the nervous system via cooling of cerebrospinal fluid, or CSF, using a solid thermally conductive material. The solid thermally conductive material is coupled to a heat exchange apparatus. The thermally conductive material may be coupled to any catheter that is used in existing clinical standard of care for acute neuronal injuries, such as catheters used to monitor and relieve intracranial pressure. The thermally conductive material is a biocompatible and solid material, for instance, metals such as steel, tungsten and titanium, and non-metallic materials such as thermal diamond paste. | 10-23-2014 |
20140316374 | DRIVE MECHANISMS SUITABLE FOR USE IN DRUG DELIVERY DEVICES - A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device. | 10-23-2014 |
20140316375 | Insulin Pump Dermal Infusion Set Having Partially Integrated Mechanized Cannula Insertion With Disposable Activation Portion - An infusion set has a partially integrated ballistic inserter that can insert a needle at a controlled rate of speed to a depth to deliver content to the upper 3 mm of skin surface, and a skin-securing adhesive layer to secure the skin surface at the insertion site such that the inserter that can insert a needle with a reduced risk of tenting of the skin surface. A removable turnkey or pushable handle can be provided to release a driving spring of the ballistic inserter to insert a needle at a controlled rate of speed, of 3.3 ft/sec. (1.0 m/sec.) up to and including those greater than 10 ft/sec. (3.0 m/sec.), then release from the set for disposal. The infusion set can further include an extendable interface ring that retracts when the inserter is removed from the infusion set. | 10-23-2014 |
20140316376 | METHOD AND DEVICE FOR PAINLESS INJECTION OF MEDICATION - A method for providing a substantially painless injection of medication into a patient, including inserting an injection needle having an outside diameter greater than 0.20 mm and less than about 0.38 mm, and injecting a medicament through the needle and into the patient at a substantially constant volumetric flow rate of about 0.05 μL/s to about 50 μL/s that provides a painless injection. The method does not require the use of an anesthetic or that the medical personnel to spend a substantial amount of time performing the injection procedure, is relatively simple and inexpensive to perform and operate, and provides a relatively high degree of safety for both the medical personnel and for the patient. | 10-23-2014 |
20140316377 | Hemostatic Devices and Methods For Use Thereof - Materials and methods for reducing or preventing bleeding and associated side effects during and after percutaneous medical procedures. | 10-23-2014 |
20140316378 | PATCH AND INFUSION SET ASSEMBLY - The invention relates to an assembly that includes an infusion set and a patch intended for receiving a pump for the transcutaneous administration of a product, said patch including an adhesive portion and a non-adhesive portion, the assembly being characterised in that said set includes patch-guiding elements and sliding elements intended for sliding along the guiding elements. | 10-23-2014 |
20140316379 | NEEDLE SHIELDING ASSEMBLIES AND INFUSION DEVICES FOR USE THEREWITH - A needle assembly includes a needle and a needle shield device. The needle shield device includes an inner shield connectable to at least one a base and a fluid connector connectable to the base, and an outer shield fixedly connected to the opposing end the needle and displaceable relative to the inner shield between a first position, in which the sharpened end of the needle is exposed outside the inner shield, and a second position, in which the sharpened end of the needle is shielded by the inner shield. Interaction between portions of the inner and outer shields during or after proximal displacement of the outer shield from the first position to the second position automatically releases or permits release of the inner shield from connection to the at least one of the base and the fluid connector. | 10-23-2014 |
20140324015 | CONTROL HANDLES FOR CATHETERS - A plunger-type control handle for controlling the deflection of a distal tip of a catheter. The control handle includes a spool driven by a gear, the spool being connected to the proximal end of at least one pull wire. For bi-directional deflection, a second proximal end of a pull wire is connected to the spool such that when one of the proximal ends is collected by the spool, the other of the proximal ends is released in an equal amount. The gear is operatively coupled to the plunger and engages a gear rack disposed on the control handle housing, such that when there is relative movement between the housing and the plunger, the gear and spool are rotated. In one embodiment, a switching mechanism is provided that reverses the rotation direction of the gear and spool, thereby providing full stroke resolution of the plunger in each of the bi-directional directions. | 10-30-2014 |
20140324016 | Methods and Devices for Renal Nerve Blocking - A method and apparatus for treatment of cardiac and renal diseases associated with the elevated sympathetic renal nerve activity by implanting a device to block the renal nerve signals to and from the kidney. The device can be a drug pump or a drug eluding implant for targeted delivery of a nerve-blocking agent to the periarterial space of the renal artery. | 10-30-2014 |
20140324017 | Adjustable Height Needle Infusion Device - An infusion set has a retraction dial that can be removably assembled with the infusion set and access a threaded needle hub contained therein such that the dial can be used to advance or retract a needle hub and an inserted needle to a more precisely controlled insertion depth to deliver insulin or other medicament intradermally (i.e. to the upper 3 mm of skin surface). Position of the inserted needle can be maintained by providing a separated and isolated needle hub, main base and main hub of the infusion set that can isolate the inserted needle from external forces such that the needle can be maintained at a depth to deliver content to the upper 3 mm of skin surface during normal use. | 10-30-2014 |
20140324018 | RESERVOIR PLUNGER POSITION MONITORING AND MEDICAL DEVICE INCORPORATING SAME - Apparatus are provided for infusion devices and related control systems and methods. In one embodiment, an infusion device includes a voided portion adapted to receive a shaft portion that includes a shaft coupled to a plunger of a reservoir. The shaft portion includes a detectable feature, and the infusion device includes a sensing arrangement proximate the voided portion to sense the detectable feature. In some embodiments, a control module is coupled to the sensing arrangement to determine a remaining amount of fluid in the reservoir based at least in part on the sensed position of the detectable feature. In other embodiments, the control module identifies an anomalous condition based at least in part on the sensed position of the detectable feature. | 10-30-2014 |
20140324019 | INFUSION DATA COMMUNICATION SYSTEM - An infusion data communication system provides a communication link among a fluid container, an infusion pump, and a patient through which identification data may be communicated. Data devices are located at the fluid container and the patient and conduct low frequency RF energy at a low power level containing the data into the medical fluid. The data-laden RF energy propagates through the medication fluid to data readers at the infusion pump which receives the RF energy and reads the data. A comparison is made to verify that the right medication is mounted to the infusion pump for administration to the right patient. RFID devices may be used for the data devices and readers. Pump programming data may also be propagated to the infusion pump from the container RFID tag. The RFID device at the patient may be writable and may be used to store a patient MAR. | 10-30-2014 |
20140324020 | Dual Purpose Advisory Device - A system for optimizing a patient's insulin treatment, comprising a drug delivery device ( | 10-30-2014 |
20140324021 | MEDICINAL PATCH AND INJECTOR SYSTEM - An injection system including a wearable component (e.g., a patch) adapted to be worn by a user, and a medication delivery component (e.g., injection device) configured to cooperate with the wearable component to deliver medication to the user. The wearable component can provide a target area to the user for targeting the medication delivery component during use, and further serve to prepare the injection site to minimize the potential for injection site reactions. Both the wearable component and the medication delivery component can include electronics and/or other devices for detecting and/or communication information regarding usage of the injection system including dose amount, frequency, time, etc. The system can be configured to communicate such information to a third party, such as a health care professional. | 10-30-2014 |
20140324022 | PROCESSES FOR DELIVERY OF VISCOUS DRUG THERAPIES - Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein. | 10-30-2014 |
20140324023 | DRUG DELIVERY SYSTEM WITH A DELAY MECHANISM - Accordingly, it is an aspect of the present invention to provide a medicament delivery system with a delay mechanism to ensure dose completion prior to activation of at least one subsystem or operation. The foregoing and/or other aspects of the present invention are achieved by providing a medicament delivery system, including a medicament container and a delay mechanism that is activated prior to completion of medicament delivery from the medicament container. The delay mechanism automatically activates a subsystem or initiates an operation subsequent to completion of medicament delivery. The foregoing and/or other aspects of the present invention are also achieved by providing a method of delivering a medicament, the method including receiving an activation command, and in response to receiving the activation command, releasing an ejection mechanism to eject medicament from a container. | 10-30-2014 |
20140330247 | SYSTEMS AND METHODS FOR ANCHORING MEDICAL DEVICES - Some embodiments of a medical device anchor system include an anchor device that secures a medical instrument (such as a catheter or the like) in place relative to a skin penetration point using subcutaneous anchors. In some implementations, the medical instrument can be coupled to the anchor device using a snap-lock cap mechanism. | 11-06-2014 |
20140330248 | SYSTEMS AND METHODS FOR IMPLANTING A MEDICAL ELECTRICAL LEAD - Implant tools and techniques for implantation of a medical lead, catheter or other implantable component are provided. The implant tools and techniques are particularly useful in implanting medical electrical leads in implant locations such as substernal spaces or subcutaneous locations. The implant tools include a sheath coupled to a sealing device. The sheath includes a continuous lumen that is in fluid communication with a passage of the sealing device. The lead is advanced through the passage and the lumen for placement of the distal end of the lead at the implant location. | 11-06-2014 |
20140330249 | Apparatus and Method for Controlled Depth of Injection into Myocardial Tissue - An injector for delivering an injectate into the myocardium of the heart may be implemented as a catheter or a handheld unit. The injector includes a body, a stabilizer secured to a distal end of the body, and a needle that may be controllably advanced from the distal end of the body. The stabilizer stabilizes the distal end of the body relative to the myocardium while the heart beats. An enlarged region disposed along the needle prevents the needle from being advanced into the myocardium beyond a desired penetration depth. To make an injection, the physician brings the distal end of the body in proximity to the myocardium, actuates the stabilizer to stabilize the distal end relative to the myocardium, and advances the needle into the myocardium. Advancement of the needle is impeded by the enlarged region, thereby placing the needle tip at the desired penetration depth for the injection. | 11-06-2014 |
20140336615 | Systems And Methods For Injecting Cellular Fluids - A system includes at least one pressurizing mechanism, a fluid path adapted to be placed in operative connection with the pressurizing mechanism to deliver an injectate to a patient, wherein the injectate includes cells, a control system operably associated with the at least one pressurizing mechanism; and at least one parameter generation system in operative connection with the control system. The parameter generation system includes an input system to receive data of a type of cells to be injected and is adapted to generate at least one parameter for the injection procedure at least in part on the basis of the data of the type of cells. The at least one parameter for the injection procedure may, for example, be a variable associated with the injectate, a variable associated with an injection protocol or a variable associated with at least one component of the fluid path. | 11-13-2014 |
20140336616 | DELIVERY DEVICE - A device for delivery of a measured or predetermined dose of an active agent to a dermal or mucosal surface comprising: a) a deformable chamber comprising at least one dome-shaped member defining a reservoir for an active agent; and b) a porated disc. | 11-13-2014 |
20140343531 | INFUSION SITE RETAINER FOR MAINTAINING INFUSION TUBING - An infusion site retainer configured to maintain tubing coupled to an infusion port includes a base configured to be secured to a patient and comprises a patient surface opposite a first surface. At least one trench is formed in the base to couple the tubing to the base. | 11-20-2014 |
20140343532 | Transdermal Delivery of High Viscosity Bioactive Agents - A device and method for delivering a high viscosity composition is described. The composition includes a bioactive agent for delivery to a subject in need thereof. The method delivers the bioactive agent at a high bioavailability and with little loss of agent to the natural defense mechanisms of the body. The device includes one or more microneedles with structures fabricated on a surface of the microneedles to form a nanotopography. A random or non-random pattern of structures may be fabricated such as a complex pattern including structures of differing sizes and/or shapes. | 11-20-2014 |
20140343533 | INFUSION PUMP WITH DRIVE DEVICE AND BLOCKING MECHANISM FOR THE INFUSION SYRINGE PISTON DRIVE HEAD - A drive device of an infusion syringe piston drive head for moving an infusion syringe piston is described. The device includes an advancing means including an advancing slide, an advancing spindle and a multi-part advancing spindle nut having at least one radially movable nut shell, and a blocking means adapted to be automatically triggered by a control sensor for blocking an infeed motion of the drive head in which the advancing slide is drivable by the advancing spindle nut at the advancing spindle and in which the drive head is arranged at the advancing slide, wherein the blocking means adapted to be automatically triggered by a control sensor includes the multi-part advancing spindle nut for blocking the infeed motion of the drive head on the advancing spindle. | 11-20-2014 |
20140343534 | Safety Needle with Positive Flush - A needle assembly including a positive flush mechanism for use with a vascular access port. The needle assembly is configured to supply fluid to the port and to provide a positive flush to overcome negative pressures in the port that can potentially occur during withdrawal of the needle from the port. | 11-20-2014 |
20140343535 | Syringe Housing To Facilitate Medication Injection - A syringe ( | 11-20-2014 |
20140350514 | SYSTEMS AND METHODS FOR INTRADERMAL DELIVERY OF THERAPEUTICS USING MICRONEEDLES - Methods are disclosed for delivering a substance to the skin of a human subject. The methods include, obtaining a substance, such as hormones, for example, Insulin; and delivering the substance into an intradermal space within the skin of the human subject through a plurality of microneedles. The microneedles are of a height of approximately 400 micrometers to approximately 750 micrometers. | 11-27-2014 |
20140350515 | Ultra Flexible Surgical Drain and Catheter - A new flexible surgical drain/catheter system is provided. The flexible system encompasses a flexible section that can be incorporated in the design of surgical drains/catheters of any kind. By incorporating this flexible system, a surgical. drain/catheter will possess three significant additional characteristics. These additional characteristics will make the herein designs superior to the existing designs. The first characteristic is that the surgical drain/catheter can be bent without causing any fold/crease to its outer and inner surfaces. The second characteristic prevents internal occlusions while the drain/catheter is bent. The third characteristic is that the flexible section can also be used as a reliable region of drain/catheter anchorage to the patient's body. | 11-27-2014 |
20140350516 | MECHANICAL SYRINGE ACCESSORY - Described herein are syringe accessories that can be attached to standard syringes. These accessories utilize one or more mechanisms that can provide at least one additional sensory feedback to the user when performing an aliquot or dosed injection. In other embodiments, the accessories can prevent overdosing. | 11-27-2014 |
20140350517 | INJECTION DEVICE WITH STRESS PROTECTION - Described are devices and systems for protection of injectable substances such as adipose cells from excessive stress or pressure during injection procedures. Further described are stress control mechanisms for detecting and/or controlling stress or pressure within injection devices. | 11-27-2014 |
20140350518 | SYRINGE EXTRUSION ACCESSORY - Described herein are syringe extrusion accessories comprising: a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one prawl operatively coupled to the handle and configured to engage with a plunger of the syringe, wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe. | 11-27-2014 |
20140350519 | CATHETER GUIDE WIRE - A catheter guidewire for facilitating introduction of a flexible catheter into the human body (e.g., into the bladder) has a proximal end having a first stiffness which is sufficient to facilitate guidance of a stiff plastic expansion sheath through the tissue. A distal end of the guide wire has a second stiffness, substantially less than the first stiffness, to avoid damage to internal walls of the bladder. Preferably, the guide wire incorporates an intermediate portion having a stiffness between the first stiffness value and the second stiffness value. | 11-27-2014 |
20140350520 | APPARATUS AND METHOD FOR ACCESSING A SINUS CAVITY - A system for accessing a sinus cavity of a subject includes an access tool configured to penetrate into the sinus cavity from a location external the subject. The system further includes an access sheath having a distal tubular portion, a lumen extending through the access sheath and the distal tubular portion and dimensioned to receive the access tool, the distal tubular portion comprising one or more cutting surfaces disposed about an external surface thereof. The one or more cutting surfaces may include a plurality of longitudinally oriented grooves for flutes disposed about the periphery of the distal tubular member. | 11-27-2014 |
20140350521 | Connector And Fluid Path Set For A Fluid Delivery System - The fluid injector system includes a source of injection fluid, a pump device, a fluid control device operably associated with the pump device, and a fluid path set in fluid connection with the source of injection fluid and the pump device. The fluid path set includes a multi-patient fluid path section adapted for fluid connection to at least one pressurizing device, a per-patient fluid path section adapted for fluid connection with a patient and comprising at least one check valve, and a connector for removably and fluidly connecting the multi-patient fluid path section with the per-patient fluid path section. | 11-27-2014 |
20140358117 | FIRING BUTTON FOR AUTOMATIC INJECTION DEVICE - Exemplary embodiments provide firing mechanism assemblies that minimize or eliminate a misfire of an automatic injection device that causes a delay in the delivery of an injection. Exemplary embodiments provide automatic injection devices including firing mechanism assemblies that minimize or eliminate a misfire that causes a delay in the delivery of an injection. Exemplary embodiments provide methods for minimizing or eliminating misfire that causes a delay in delivery of an injection in automatic injection devices. Exemplary embodiments provide methods for using automatic injection devices that are free of a misfire that causes delay in delivery of a therapeutic substance into a patient's body. | 12-04-2014 |
20140358118 | Protector And Method For Using Same - A protector ( | 12-04-2014 |
20140358119 | Nighttime Basal Dosing Device - A basal hub for attaching to an infusion base is disclosed. The hub includes a fluid reservoir and pressure actuating device. A septum portion of the reservoir is configured to be opened by a flow cannula that is in fluid communication with an infusion cannula of the infusion base, when the basal hub is attached to the infusion base. The pressure actuating device applies pressure to the fluid reservoir, such that when the septum portion of the fluid reservoir is pierced by the by the flow cannula, liquid stored in the fluid reservoir is released from the fluid reservoir into the infusion cannula of the infusion base via the flow cannula. The basal hub is configured to deliver a basal dose of insulin during periods of inactivity, such as during sleep time. | 12-04-2014 |
20140364830 | INJECTOR AUTO PURGE - An auto purge for an intravenous contrast injector of the type having a motor which advances a plunger drive ram and configured for use with a pre-filled or user-filled syringe containing an approximate known amount of air including a processor which causes the motor to move and a memory storing a predetermined purge stop point representative of the approximate known amount of air in the syringe, the injector configured to automatically advance the plunger drive ram an amount substantially equal to the predetermined purge stop point representative of the approximate known amount of air contained in the syringe. | 12-11-2014 |
20140364831 | REVOLVING MULTI-CARTRIDGE HYPODERMIC SYRINGE AND METHOD OF USE - A revolving multi-cartridge syringe device includes a needle and two or three revolving holders, each for receiving a cartridge containing medical fluid to be injected. The holders can be pre-loaded with the cartridges, with a first cartridge placed in a loaded position ready to dispense. After fluid in the first cartridge is injected into a patient, a second holder and cartridge are revolved into the loaded position, without breakdown of the syringe. The process can be repeated with a third cartridge. The engagement of each cartridge with the needle, retraction from the needle, and rotation of the revolving holder are all implemented by sliding a sliding actuator in either a first direction or a second, opposite, direction, depending on which action is desired. Thus, injection and reloading of the cartridges can be easily actuated by the user through manipulation of a single slidable actuator, without requiring withdrawing the needle from the mouth area to reload. | 12-11-2014 |
20140364832 | TAMPONADE TROCAR DEVICE AND METHOD - A tamponade trocar includes an elongate balloon having a closed distal end and is adapted to expand from a small diameter to a large diameter. A cannula is positioned at a proximal portion within the balloon lumen. A rigid stylet is removably positioned within the balloon and cannula lumens. A distal end of the stylet supported balloon is inserted into a perforation in a body wall and advanced into a body cavity while the balloon is unexpanded. The balloon is expanded and the cannula is advanced to a distal portion of the balloon lumen and across the body wall. At this stage, the perforation is dilated and in compressive tamponade. The proximal portion of the balloon may be removed and a seal housing may be coupled to the proximal end of the cannula. The distal end of the balloon may be punctured and opened, making the trocar ready for use. | 12-11-2014 |
20140371710 | IN VIVO DRUG DEVELOPMENT AND DELIVERY SYSTEMS AND METHODS - The present disclosure generally pertains to in vivo drug development and delivery systems and methods. The systems include a hollow tubular assembly with a chamber for receiving and transmitting an ionizing substrate solution, and a structure to transmit non-radioactive ionizing radiation to the ionizing substrate solution. The resulting free radical drug is transferred directly into a patient treatment site through an applicator. The systems and methods described herein provide simple, inexpensive techniques for in vivo production of an optimal chemotherapeutic drug without the use of radioactive radiation and directly injecting the drug into the patient's tissue with very minimal systemic side-effects. | 12-18-2014 |
20140371711 | METHODS AND DEVICES FOR PROTECTING CATHETER TIPS AND STEREOTACTIC FIXTURES FOR MICROCATHETERS - Methods and devices are disclosed herein that generally provide protection for devices (e.g., microcatheters) having small tips. Methods and devices are also disclosed herein that generally facilitate use of commercially-available stereotactic systems with devices (e.g., microcatheters) having small tips. | 12-18-2014 |
20140371712 | CONVECTION ENHANCED DELIVERY APPARATUS, METHOD, AND APPLICATION - An embodiment of the invention is directed to a microfabricated, silicon-based, Convection Enhanced Delivery (CED) device. The device comprises a silicon shank portion, at least one individual parylene channel disposed along at least a part of an entire length of the shank, wherein the channel has one or more dimensioned fluid exit ports disposed at one or more respective locations of the channel and a fluid (drug) input opening. The fluid input opening may be configured or adapted to be connected to a fluid reservoir and/or a pump and/or a meter and/or a valve or other suitable control device(s) or apparatus that supplies and/or delivers fluid (e.g., a drug) to the microfabricated device. The device may have multiple channels disposed side by side or in different surfaces of the device. The device may be rigid, or flexible, in which case a flexible device can be attached to a bio-degradable support scaffold that provides sufficient structural rigidity for insertion of the device into the target tissue. In certain “functionalized” embodiments of the invention, the CED device is equipped with integrated electrodes and/or a sensor (e.g., glutamate) to detect and convey selective parametric information. Another embodiment of the invention is directed to a CED method for drugs and/or other agents. The method may comprise the delivery of enzymes or other materials to modify tissue permeability and improve drug diffusion. Another embodiment of the invention is directed to a method for making a device for CED of drugs. | 12-18-2014 |
20140371713 | SHORT-TIME SOLUBLE MICRONEEDLE - According to the present invention, a microneedle material capable of dissolving in a short-time and being absorbed quickly in order to shorten the application time of the microneedle is provided. | 12-18-2014 |
20140371714 | DEVICES, SYSTEMS AND METHODS FOR MEDICAMENT DELIVERY - An apparatus includes a label configured to be coupled to a medicament delivery device. The label includes a first surface and a second surface. The first surface is configured to be coupled to an outer surface of the medicament delivery device. The second surface includes a textual indicia. The label further includes an electronic circuit system configured to output an electronic signal. | 12-18-2014 |
20140378940 | Anti-nociceptive apparatus - The present invention presents an apparatus and methods to generate and deliver circumferential mechanical vibrations to a hypodermic needle penetration site of a human body to reduce pain of needle prick by activating inhibitory neuronal mechanisms for pain perception. The apparatus comprises a detachably disposable proximal end that contacts with a tissue of a recipient and encircles a needle penetration site, a distal end that is configured as a conduit for electric power to the apparatus and a longitudinally tubular handle assembly that is connected to both proximal and distal ends and that houses a vibration assembly and a control and power assembly. The vibration assembly generates and delivers resonant vibrations to the recipient through the proximal end. A needle penetrates the recipient's tissue circumferentially surrounded by vibrations transmitted by the proximal end. | 12-25-2014 |
20140378941 | CORTICAL POTENTIAL MONITORING - Techniques, devices, and systems may include screening effective therapies using cortical evoked potentials. In one example, a system may be configured to receive a first sensed cortical evoked potential of a patient that occurred in response to an induced sensation at an anatomical region different from a brain region of the patient and receive a second sensed cortical evoked potential that occurred in response to electrical stimulation delivered to one or more nerves associated with the anatomical region. The electrical stimulation may be at least partially defined by a set of therapy parameter values. The system may also compare a first value of a characteristic of the first sensed cortical evoked potential to a second value of the characteristic of the second sensed cortical evoked potential and determine, based on the comparison, efficacy of a therapy configured to treat a condition associated with the anatomical region. | 12-25-2014 |
20140378942 | Implantable Access Port Including Fluid Handling Features - An access port for subcutaneous implantation into a body of a patient is disclosed. The port is typically subcutaneously connected to a catheter, a distal portion of which is disposed within a vein or other vessel of the patient. The port is configured with enhanced fluid handling features to improve fluid flow therethrough while reducing the likelihood of clotting or occlusions in the attached catheter, thus improving system patency. In one embodiment, for instance, an implantable access port is disclosed and comprises a body defining a reservoir, a needle-penetrable septum covering an opening to the reservoir, a stem defining an outlet to the reservoir, and a deformable element included in the reservoir. The deformable element is operably connected to a main portion of the septum and deforms in response to displacement of the septum to counteract a change in volume within the reservoir and prevent blood ingress into the catheter. | 12-25-2014 |
20140378943 | AMBULATORY INFUSION SYSTEM WITH DETACHABLE DRUG CONTAINER - Methods and devices for drug infusion and for storing a drug container. The methods and devices can include ambulatory infusion systems and dosing units. The dosing units can have and an inlet port for attachment to an external liquid drug container, an outlet port, a pump kernel, and a control valve. | 12-25-2014 |
20140378944 | METHODS FOR DRUG DELIVERY - Methods and devices for delivering an agent to a solid tissue in vivo for assessment of efficacy are described. One method involves withdrawing of a needle from and injecting of the agent into the solid tissue; another method involves delivering the agent using a plurality of microdialysis probes to a solid tissue. | 12-25-2014 |
20150011971 | Anti-nociceptive apparatus - The present invention presents an apparatus and methods to generate and deliver resonant vibrations to a hypodermic needle penetration site of a human body to reduce pain of needle prick by activating inhibitory neuronal mechanisms for pain perception. The apparatus comprises a longitudinal syringe carriage assembly which releasably holds and slidably moves a proximal portion of a syringe and a vibration assembly which generates and delivers vibrations to a vibration resonance enclosure located at a proximal end of the apparatus. The vibration assembly adjoins in parallel the syringe carriage assembly. A syringe with a needle moves forward in the syringe carriage assembly along a longitudinal axis and the needle penetrates a recipient's tissue which is in direct contact with and is vibrated by the proximal end of the apparatus. | 01-08-2015 |
20150011972 | PUNCTURE NEEDLE DEVICE AND METHOD OF USING THE SAME - The present invention provides a puncture needle device, comprising a light source assembly, an optic fiber assembly, an ejection assembly, and a puncture needle assembly, wherein the light source assembly comprises a light source sleeve configured with a light source, the optic fiber assembly comprises an optic fiber sleeve configured with an optic fiber, the ejection assembly comprises an ejection sleeve configured with an ejection spring, and the puncture needle assembly comprises a puncture needle with a catheter. | 01-08-2015 |
20150011973 | DEVICES, SYSTEMS, AND METHODS FOR MEDICAMENT DELIVERY - Certain exemplary embodiments comprise can comprise an auto-injector, which can comprise: a vial configured to store and/or contain an injectable medicament, the vial defining a vial longitudinal axis, and a housing comprising the vial. In various embodiments, the injectable medicament can be a medicine, medication, drug, pharmaceutical, prescriptive, agent, antidote, anti-venom, hormone, stimulant, vasodilator, anesthetic, and/or nutritional supplement that is substantially ready for injection. | 01-08-2015 |
20150011974 | PEN NEEDLE TIP - A needle tip assembly for a pre-loaded syringe or a pen needle injection device, the needle tip assembly including a body comprising a double-ended needle and being installable and removable from the pre-loaded syringe or pen needle injection device. A needle cap is configured to cover a skin puncturing end of the double-ended needle and is removable to exposed the skin puncturing end. An outer safety member has a first portion that surrounds the body and a second portion that surrounds the skin puncturing end. | 01-08-2015 |
20150011975 | SYRINGE ASSEMBLY - A syringe assembly which has a barrel for containing one or more medicaments and a stopper disposed in the barrel defining and separating a first volume and a second volume within the syringe assembly. The stopper includes a permanent seal fluidly sealing the stopper to the barrel about the entire perimeter of the stopper intermediate the first volume and second volume, and a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the second volume and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable between a sealing configuration and an open configuration to selectively seal the channel from the first volume and is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume or second volume exceeding a first pressure threshold. | 01-08-2015 |
20150018797 | MOTORIZED DRUG DELIVERY DEVICE WITH NEEDLES AND ROLLER - A delivery device ( | 01-15-2015 |
20150018798 | BRUISELESS CANNULA - A needle device including a housing. The housing includes a first housing element provided towards a proximal end of said needle device and a second housing element provided towards a distal end of said needle device. A cutting element having a sharp proximal end is arranged at a proximal end of said first housing element. A cannula having a blunt proximal end is fitted to the second housing element and an opening for the cannula is provided at the proximal end of the first housing element. The first housing element and the second housing element are moveable relative to each other between an extended position where the proximal end of the cannula does not extend beyond the proximal end of the cutting element and a compressed position where the cannula extends through the opening of the first housing element and past the proximal end of the cutting element. | 01-15-2015 |
20150018799 | DRUG STORAGE APPARATUS - Fluid storage apparatus for medical use is described that includes a length of tubing having a first end and a second end. A first sealable connector portion is provided at the first end and a second sealable connector portion is provided at the second end. The volume of fluid that can be stored within the apparatus is known and an infusate or therapeutic agent is contained within the apparatus. In this manner, a known volume of therapeutic agent can be infused to a patient. The use in neurosurgical applications is described. | 01-15-2015 |
20150025497 | Adaptive Volume Per Motor Revolution System and Method - A patient care system is configured for infusing fluid to a patient. The system includes at least one fluid infusion pump connected to a respective fluid supply for pumping the contents of a fluid supply to a patient via fluid supply lines. The system includes a programming module that determines the efficiency of the fluid infusion pumps and dynamically adapt the infusion pumps based on one or more system parameters. | 01-22-2015 |
20150025498 | Infusion Pump System and Method - Some embodiments of an infusion pump system may be configured to wirelessly communicate with other devices using near field communication (NFC). In particular embodiments, by incorporating near field communication capabilities into the infusion pump system, user communications with the infusion pump system can be enhanced and simplified. | 01-22-2015 |
20150025499 | DETECTING UNINTENTIONAL MOTOR MOTION AND INFUSION DEVICE INCORPORATING SAME - Apparatus are provided for infusion devices and related systems and operating methods. An exemplary system includes a motor, a sensing arrangement coupled to the motor to provide output indicative of a detected characteristic of the motor when the sensing arrangement is enabled, and a module coupled to the sensing arrangement to periodically enable the sensing arrangement while the motor is idle and detect potential unintended motion of the motor based on the output from the sensing arrangement while periodically enabling the sensing arrangement. In some embodiments, the motor includes a rotor configured such that its rotation provides translational displacement of a plunger in a fluid reservoir, and the sensing arrangement includes one or more sensors configured to provide output indicative of a detected magnetic field of the rotor magnet. | 01-22-2015 |
20150025500 | APPARATUS AND METHOD FOR INTRAOSSEOUS FLUID INFUSION - A system allows for rapid intraosseous delivery of fluids from a fluid reservoir via an intraosseous port having a tip disposed within the bone marrow of a patient. The system includes a housing with a chamber and a plunger. An actuator is moveable between first and second positions to move the plunger between the distal and proximal positions. A valve housing includes a first one-way valve fluidly coupled to the fluid reservoir, and a second one-way valve fluidly coupled to the intraosseous port. The valves of the valve housing are oriented such that movement of the actuator from the first to the second position moves the plunger from the distal to the proximal position, drawing fluid from the fluid reservoir through the first valve and into the chamber. Movement of the actuator from the second to the first position moves the plunger from the proximal to the distal position, driving fluid from the chamber through the port and second valve and through the intraosseous port. A grip manipulated by a user effects movement of the actuator, which provides sufficient mechanical advantage for the user to easily overcome resistance to the flow of fluid into the bone marrow. The plunger may be biased in the proximal position such that it is automatically retracted to that position, causing re-filling of the chamber, when the user releases forces imparted to the grip. The tubing and valve mechanism are of sufficient caliber to allow rapid and low-resistance flow of fluid from the reservoir into the chamber. The combination of these components allows rapid infusion of large volumes into the bone marrow without user fatigue, and requiring only one hand to operate the mechanism. | 01-22-2015 |
20150025501 | Composition and Method for the Treatment or Prevention of Spinal Disorders - The present invention provides compositions of matter suitable for the prevention of and/or treatment of a spinal disorder and/or spinal pain, e.g., caused by and/or associated with intervertebral disc (IVD) degeneration, and methods of treatment of a spinal disorder and/or spinal pain. For example, the compositions of the present invention comprise a modulator of growth differentiation factor (GDF)-6 signaling sufficient to reduce or prevent or delay IVD degeneration and/or to enhance or induce IVD regeneration. The present invention also provides medical devices comprising such compositions, and methods of treatment making use of such compositions. | 01-22-2015 |
20150025502 | SYRINGE CRADLE - A syringe cradle for holding a syringe, the syringe cradle comprising a syringe holder at a proximal end for engaging a barrel of a syringe and a rider for pressing on a plunger of the syringe, a cylindrical body for surrounding the syringe, a distal cap for closing a distal end of the cylindrical body, a stepwise advancing mechanism for advancing the rider along the cylindrical body towards the proximal end, and a stopping mechanism to prevent the rider from moving backwards towards the distal end of the cylindrical body. | 01-22-2015 |
20150025503 | Wireless Communication for On-Body Medical Devices - Apparatuses, systems and methods for the wireless communication of medical devices in a subcutaneous fluid delivery system are disclosed. A system for subcutaneous fluid delivery includes a primary patch pump adapted to attach a first infusion cannula to a user and to perform a plurality of primary patch pump functions, and a secondary patch pump adapted to attach a second infusion cannula to a user. The secondary patch pump is further adapted to perform a plurality of secondary patch pump functions substantially similar to the plurality of primary patch pump functions if an error condition associated with the primary patch pump is determined. | 01-22-2015 |
20150025504 | NEURAL INJECTION SYSTEM AND RELATED METHODS - A novel neural injection system and related methods are herein disclosed. Various embodiments of an embodiment of a neural injection system of the present invention provide for at least one benefit of enhanced injection characteristics, increased operational efficiency, reduced cost per unit, reduced incidence of injury through intraneural/intravascular injection, reduced incidence of injury through pricking/piercing, and/or the like. | 01-22-2015 |
20150032084 | MOTION ACTIVATED SEPTUM PUNCTURING DRUG DELIVERY DEVICE - A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum. | 01-29-2015 |
20150038941 | DRUG DELIVERY IMPLANTS - An orthopaedic implant system includes an external fixation device implantable at a selected location within a corporeal body and configured for delivering at least one therapeutic agent to the corporeal body. The external fixation device includes an implantable pin, a sheath coupled with the pin, a reservoir coupled with the sheath and a plurality of channels. The pin defines the plurality of channels. The reservoir is configured for receiving the at least one therapeutic agent. The plurality of channels are configured for conveying the at least one therapeutic agent from the reservoir to a treatment site relative to the corporeal body. | 02-05-2015 |
20150038942 | Syringe Assembly and a Needle Unit for Attachment to a Syringe Unit to Form a Syringe Assembly - A retractable syringe is proposed having a cutting head mounted on a plunger of the syringe. When the plunger is advanced to expel fluid from the syringe, the cutting crown cuts a retention mechanism which holds a needle unit of the syringe, allowing a drive mechanism to drive the needle unit into the syringe. The cutting crown is shaped to reduce the force which has to be applied to cut the retention mechanism. Furthermore, a disposable needle assembly for attachment to a syringe unit is proposed. The disposable needle assembly has a needle and connector element for connecting the needle to the syringe unit. The connector element encircles the needle and has a thread on its outer surface for mating with the syringe unit. | 02-05-2015 |
20150045768 | DELIVERY NEEDLE WITH ELEVATOR/PADDLE FOR MICRONIZED ALLOGRAFT TISSUE - Techniques, kits and a delivery instrument for providing a material at a defect repair site. The instrument is a combined delivery needle/elevator/paddle that includes a delivery needle and a paddle/elevator tip attached to the end of the needle and around the most distal opening of the needle. The combined needle/elevator/paddle instrument allows both delivery (insertion or injection) of the material/mixture as well as leveling/flattening of the delivered material. The mixture/material may be micronized allograft tissue such as BioCartilage® and the surgical site may be a defect site such as a microfracture site or cartilage defect. | 02-12-2015 |
20150045769 | INJECTION DEVICE FOR MINIMALLY INVASIVE PROCEDURES AND USES THEREOF - Provided herein is an injection device that can be used in minimally invasive procedures, such as laparoscopic surgeries, for direct administration of a fluid, such as a therapeutic, to a target tissue or organ. | 02-12-2015 |
20150045770 | ADVANCED STEP THERAPY DELIVERY FOR AN AMBULATORY INFUSION PUMP AND SYSTEM - Embodiments relate to systems, methods and devices for delivering a drug or other therapy to a patient with an ambulatory infusion pump configured to provide a series of tolerance-building steps leading up to a plateau delivery rate. The plateau delivery rate is maintained until the prescribed amount of drug or therapy fluid is delivered to the patient. Embodiments of the invention include providing the patient or other user with a mechanism to decrease, or step down, the therapy delivery rate if a tolerance was not achieved at a lower rate, and providing notifications prior to a step up in a dosage delivery rate. | 02-12-2015 |
20150051578 | Prefilled Safety Pen Needle - A pre-filled, single-use injection device includes a passive dual shield on the patient end of the needle. The device is self-contained so that the entire needle is shielded after use without a separate passive shield system for the non-patient end. | 02-19-2015 |
20150051579 | DEVICES HAVING THERMOCHROMIC RESPONSE INDICATORS - The present invention relates to medical devices, in particular autoinjectors and syringes having one or more thermochromic response indicators that are sensitive to temperature changes of a drug formulation or solution. The present invention provides for a pre-filled delivery device comprising a syringe, a cartridge, or a capsule having a barrel, where the barrel is marked on the outer surface with a first thermochromic indicator, and wherein the thermochromic indicator is responsive to temperature changes of the drug formulation or solution within the barrel. | 02-19-2015 |
20150051580 | SELECTABLE SINGLE DOSE AUTO-INJECTOR AND METHODS OF MAKING AND USING SAME - An auto-injector device for administering a liquid pharmaceutical composition, in which an end-user can select between doses that the device is capable of delivering. The end-user choices that translate into the selected doses can be based on end-user perceived severity of symptoms, end-user weight and other such factors. In some embodiments the auto-injector is configured to administer the one chosen dose only. In other embodiments, the auto-injector can deliver second and subsequent doses up to full dose of the pharmaceutical composition disposed in the injector. The auto-injector can provide visual, audio, and tactile feedback, alone or in combination, to the user to indicate the dose selected, instructions for use, and when the dose has been administered. | 02-19-2015 |
20150051581 | APPARATUS AND METHODS FOR OCULAR INJECTION - An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location. | 02-19-2015 |
20150051582 | Microneedle-Based Pen Device For Drug Delivery And Method For Using Same - A system and method is provided for an injectable substance delivery pen comprising a microneedle hub assembly removably engaged with a pen device body which includes a cartridge, a plunger, and a drive mechanism. The hub assembly includes at least one microneedle for intradermal or shallow subcutaneous injection of the contents of the cartridge. The cartridge, plunger and drive mechanism components of the pen body are fabricated of non-compliant and non-compressible materials to allow effective communication of the cartridge contents via the microneedle patient interface. | 02-19-2015 |
20150057637 | Extended Hub for a Safety Pen Needle - A shielded pen needle assembly is provided in which the hub extends distally beyond an outer sleeve of the assembly. | 02-26-2015 |
20150065990 | APPARATUS AND METHOD FOR AN INTEGRATED REUSEABLE INJECTION DEVICE WITH A MEDICINE VIAL FOR HOME USERS - A portable handheld fluid-medicine-injection device for individual users, has a medicine vial has a substantially rectangular cross section that reduces a thickness profile of the device and a dispense mechanism coupled with the vial, the dispense mechanism has an inject push rod inside a threaded cylinder that reduces a length profile of the device. The device has a needle with a needle mount/dismount mechanism coupled with the medicine vial and a needle storage mechanism that stores the needle when not in use and replenishes the needle for reuse. | 03-05-2015 |
20150065991 | VIAL DOSING SYSTEMS AND METHODS - Vial dosing systems and methods are disclosed. A vial dosing device includes a connecting body coupleable to a vial, a cannulated plunger having a proximal end coupled to the connecting body, a dose chamber adapted to slidably receive a distal end of the cannulated plunger and to expel medicament through a distal end of the dose chamber, and a plunger tip check valve coupled to the cannulated plunger and adapted for fluid flow from the cannulated plunger through the plunger tip check valve into the dose chamber. | 03-05-2015 |
20150065992 | SYRINGE WITH INTEGRAL AMPULE - A syringe having an integral ampule is disclosed. The syringe includes a barrel defining a reservoir configured to store a fluid and a plunger defining an inner cavity. The plunger includes an ampule within the inner cavity, where the ampule seals the fluid. The plunger also includes a cap at a proximal end of the plunger that is configured to move distally relative to the plunger, and a first one-way valve at the distal end of the plunger. The distal movement of the cap relative to the plunger causes an opening within the ampule. A method of injecting a fluid within a patient using a syringe having an integral ampule is also disclosed. | 03-05-2015 |
20150065993 | DOUBLE-CHAMBER MIXING SYRINGE AND METHOD OF USE - Described is a syringe housing at least one removable carpule containing at least two injectable solutions and having a mixing chamber for mixing two injectable solutions during administration of the solutions, and methods of using the syringe. | 03-05-2015 |
20150073382 | ROTATABLE HYPODERMIC NEEDLE AND METHOD OF USE - One possible embodiment of the invention could be a hypodermic needle that rotatably connects to a shield comprising a hypodermic needle denoted into a distal needle portion and a proximal needle portion, the distal needle portion's injection aperture continuously connected to the proximal needle portion's connection aperture; a shield that comprises at least a skin pad portion, the proximal needle portion being rotatably held within a portion of the shield in a manner that allows the distal needle portion to be moved between an operative position, wherein the distal needle portion descends downward and away from a bottom of the skin pad portion to hold the needle tip away from the skin pad portion to a stored position that has the needle tip of the distal needle portion placed proximate to the skin pad portion. | 03-12-2015 |
20150073383 | High Efficiency Auto-Injector - An auto-injector apparatus and associated methods utilizing specific dimensions and parameters of use for the auto-injector are provided for achieving increased effectiveness of the auto-injector device in delivering medicament into the patient's body, and in dispersion of the medicament from the initial injection site into the surrounding bodily tissues. | 03-12-2015 |
20150073384 | Injection Mechanism Utilizing a Vial - An injection device is provided for delivering a liquid medicament. The injection device includes a housing with a first chamber for storing a supply of the medicament. The first and second chambers are coupled within the housing. The second chamber is in fluid communication with the first chamber. The injection device also includes an outlet port for dispensing the medicament outside the housing. The outlet port is coupled to the housing and in fluid communication with one of said first and second chambers. | 03-12-2015 |
20150073385 | REMOTE RESERVOIR MICRONEEDLE DRUG DELIVERY SYSTEMS - Transdermal drug delivery patch devices are described in which microneedle array insertion or application forces are decoupled or separated from drug delivery actuation or application forces. Dual-reservoir devices are described in detail for such purposes as are associated methods of use in various examples. | 03-12-2015 |
20150073386 | Infusion Pumps - Ambulatory infusion pumps, pump assemblies, and baseplate assemblies, including cartridges, baseplates, cannulas, inserters, and related components and batteries therefor, as well as component combinations and related methods. | 03-12-2015 |
20150080845 | POLYMER SYSTEM FOR SECURING IMPLANTS IN SYRINGE NEEDLES - Disclosed herein are methods of delivering implants to a target organ with an implant administration device, where the implant administration device includes a polymer retainer. Methods of making polymer retainers and methods of securing an implant within an implant administration device using a polymer retainer are also disclosed herein. | 03-19-2015 |
20150080846 | INSERTION AND REMOVAL METHODS AND APPARATUS FOR THERAPEUTIC DEVICES - Described herein is an apparatus to insert an implantable therapeutic device into a patient. The apparatus includes a proximal handle ( | 03-19-2015 |
20150080847 | MEDICAMENT, METHOD, AND DRUG DELIVERY DEVICE FOR TREATMENT OF OVARIAN CANCER - Drug delivery devices, medicaments, and methods are provided for the intraperitoneal treatment of ovarian cancer. An implantable device for drug delivery includes an elongated, flexible device having a housing defining a reservoir that contains a drug in solid or semi-solid form, and configured to be wholly deployed within the peritoneal cavity of a patient and continuously release a therapeutically effective amount of the drug over a period of at least 24 hours. A medicament includes cisplatin for administration into the peritoneal cavity of a patient continuously over a treatment period of at least 24 hours. A method of drug delivery includes implanting within the peritoneal cavity of a patient an elongated, flexible device having a reservoir containing a drug, solubilizing the drug at least in part with peritoneal fluid, and releasing an effective amount of the solubilized drug from the reservoir continuously for a period of at least 24 hours. | 03-19-2015 |
20150080848 | PUNCTURABLE MEMBRANE FOR SAFETY SYRINGE - A safety syringe may define a variable fluid chamber and detached needle assembly. The variable fluid chamber may be hermetically sealed off from the environment or ambient air until the needle assembly is attached to a syringe body of the safety syringe. A proximal end of the variable fluid chamber is sealed off from the environment via a seal between a piston and syringe body. The distal end of the variable fluid chamber may be sealed off from the environment via a barrier covering the distal end of the syringe body. The barrier may be punctured to allow fluid to through tberethrough at or about the same time when the needle assembly is attached to the distal end portion of the syringe body. | 03-19-2015 |
20150080849 | MULTIPART FLUID SYSTEM AND A SYSTEM FOR REGIONAL CITRATE ANTICOAGULATION IN AN EXTRACORPOREAL BLOOD CIRCUIT - A method of treating blood withdrawn from patient including: simultaneously withdrawing blood and infusing withdrawn blood from and to the patient by flowing the withdrawn blood through an extracorporeal dialysis circuit including a dialyzer having a semi-permeable dialysis membrane and a dialysate side adjacent the membrane; feeding a dialysate containing 1 to 5 mM total calcium and 2 to 8 mM citrate to the dialysate side of the dialyzer, and introducing an anticoagulation fluid including at least 8 mM citrate into the | 03-19-2015 |
20150088091 | Indicia Informative of Characteristics of Insertable Medical Devices - A system by which resource information relating to an insertable medical device, such as an intravascular catheter, can be identified by its source so as to be accessed by a practitioner, caregiver, or patient, is disclosed. In particular, a resource information key is included at a predetermined key location on or proximate to the medical device, wherein the key indicates the source of the resource information. In one example embodiment, therefore, an insertable medical device for establishing intravascular access to a patient, such as a peripherally inserted central catheter (“PICC”), is disclosed and comprises: an internal portion, and a portion external to the patient that includes a resource information key indicating a website where a user can acquire resource information relating to the medical device. In other embodiments indicia are provided as quick response (“QR”) codes, and as various markings to indicate compatibility of the medical device with ethanol. | 03-26-2015 |
20150088092 | Drug Delivery Device and Method for Detection of End-Of-Dose Condition - Method for detecting an end-of-dose condition in a pressurized system, comprising the steps of (a) providing a system having a fluid-filled variable volume reservoir comprising an elastically deformable portion and an outlet, pressurizing means, and means for detecting a property of the elastically deformable portion which varies with the internal pressure in the reservoir, (b) pressurizing the reservoir to expel a desired amount of fluid by applying a force, thereby deforming the elastically deformable portion, (c) measuring, after the actuating step, a property related to the elastically deformable portion as it regains its initial configuration, (d) comparing a value for the measured property with one or more threshold values, and (e) providing a user with an indication when a given threshold value has been reached, and/or when a given threshold value has not been reached within a given period of time. | 03-26-2015 |
20150088093 | IMPLANTABLE MEDICAL DEVICES STORING GRAPHICS PROCESSING DATA - In one example, a device includes a telemetry module configured to retrieve graphics processing data from a device that is not configured to perform a rendering process using the graphics processing data and that is associated with delivering therapy to a therapy target of a patient, and a control unit configured to apply the graphics processing data while performing the rendering process to generate an image of an anatomical feature of the patient, wherein the anatomical feature comprises the therapy target for an implantable medical device, and to cause a display unit of a user interface to display the image, wherein the image of the anatomical feature is specific to the patient. The graphics processing data may include a list of vertices or a transform to be applied to a non-patient-specific anatomical atlas. The data may also include a location of a therapy element of the implantable medical device. | 03-26-2015 |
20150094685 | CATHETERS INCLUDING BEND INDICATORS, CATHETER ASSEMBLIES INCLUDING SUCH CATHETERS AND RELATED METHODS - Epidural catheters include a tubular member and at least one bend indicator located proximate a distal end of the tubular member to provide a reference point for a user to bend the catheter. Catheter assemblies may include such catheters. Methods of inserting an epidural catheter having a bent distal end into a patient include bending a catheter at a location proximate at least one bend indicator formed proximate a distal end of the catheter and inserting at least a portion of the catheter into a patient. Methods of making an epidural catheter include forming a tubular member having a proximal end and a distal end and forming at least one bend indicator on the catheter proximate the distal end of the tubular member to provide a reference point for a user to bend the catheter. | 04-02-2015 |
20150094686 | NEEDLE BASED HELICAL COIL SAFETY DEVICE - The present disclosure describes anti-needle stick safety mechanism that is passively activated during the normal course of giving an injection. In one embodiment, the device includes a spring member coupled at a proximal end to a needle member and at a distal end to a needle cover. The passive activation of the device is triggered when the needle is inserted to a minimum depth into the patient's tissue to unleash the force of a compressed spring to urge a needle cover towards the distal end of the needle. As the needle is withdrawn from the tissue, the needle cover advances to the end of the needle and as it partially clears the end of the needle, it adopts an orientation that prevents the needle tip from re-emerging from the needle cover. | 04-02-2015 |
20150094687 | Dosing and Drive Mechanism for Drug Delivery Device - The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device. | 04-02-2015 |
20150094688 | Disposable Inserter for Use With a Medical Device - An inserter and methods of using embodiments of the inserter are described. The inserter includes a housing having a cannula assembly and an insertion mechanism. Two buttons are located on the inserter and are concomitantly actionable for actuation of the insertion mechanism, wherein the insertion mechanism is configured to place a cannula assembly in a well that is disposed on the cradle. The inserter also includes a first parts and second part, whereby the first part includes a handle and the second part comprises the entire insertion mechanism, whereby the first and second part are connected via an indentation. | 04-02-2015 |
20150100039 | DEVICE FOR EXTERNAL PERCUTANEOUS CONNECTIONS - The present invention provides devices for creating an external percutaneous fluidic connections. In one embodiment, a needle is configured for extending through an endoscope. The needle includes a distal sharp tip and a lumen extending therethrough. The needle extends out of the endoscope within a body cavity to create an incision through a patient's skin. A safety cap is attached over the distal sharp tip without occluding the needle lumen. A wire is inserted through the needle lumen such that it extends from outside the body at the incision, through the body, and outside the body at the patient's mouth. After removing the needle and the endoscope from the body, a PEG device is coupled to the wire at the patient's mouth, and the PEG device is delivered through the upper GI tract and out through the incision. | 04-09-2015 |
20150105749 | DISPENSE INTERFACE FOR AN EJECTION DEVICE - The invention inter alia relates to a dispense interface for an ejection device. The dispense interface comprises at least two inlets, at least one outlet and a part having a body portion and a cover portion; wherein the body portion and the cover portion are connected by a living hinge such that the body portion and the cover portion are foldable towards each other; wherein the body portion and the cover portion are configured to form a fluid channel arrangement between surfaces of the body portion and the cover portion facing each other when the body portion and the cover portion are folded towards each other; wherein the living hinge is arranged next to the facing surfaces; and wherein the fluid channel arrangement is configured to provide fluid communication between the at least two inlets and the at least one outlet. | 04-16-2015 |
20150112301 | APPARATUS AND METHOD FOR ENDOLUMINAL STENT TRANSIT - An endoluminal stent transit device. The endoluminal stent transit device includes a wire having a distal end and a proximal end, and a guide element attached to the wire at the distal end, which is movable between a first position and a second position. The guide element in the first position is in a contracted configuration while located within a lumen of a catheter and has a first diameter smaller than the catheter, and in the second position is in an expanded configuration while located outside of the lumen of the catheter and has a second diameter larger than the catheter. | 04-23-2015 |
20150112302 | METHODS AND SYSTEMS FOR INHIBITING FOREIGN-BODY RESPONSES IN DIABETIC PATIENTS - Methods and devices are provided for reducing a diabetic patient's foreign body immune response, including infusion site-loss and/or occlusion. Such foreign body responses are associated with the treatment of the diabetic patient where the treatment requires subcutaneous implantation of a foreign body, such as a cannula or catheter. In certain embodiments of the invention, a response-inhibiting agent is administered to a patient at the site of cannula/catheter insertion, thereby facilitating delivery of insulin to the diabetic patient and mitigating site-loss and/or occlusion over a period of time. | 04-23-2015 |
20150119849 | METHODS AND DEVICES FOR ACTIVATING BROWN ADIPOSE TISSUE WITH COOLING - Methods and devices are provided for activating brown adipose tissue (BAT) with cooling. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a medical device is provided that activates BAT by cooling tissue having a high density of cold sensitive thermoreceptors and/or by cooling BAT depots directly, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure. | 04-30-2015 |
20150119850 | Maintenance of Bronchial Patency by Local Delivery of Cytotoxic, Cytostatic, or Anti-Neoplastic Agent - Methods for maintaining patency in a bronchus of a patient are presented. A catheter is positioned within the bronchus. A target region of one or more of a bronchial wall, submucosa, media, and adventitia is punctured at or adjacent a location of a debulked bronchial carcinoma with an injection needle disposed on a distal end of the catheter. Such puncturing is achieved by expanding a balloon disposed on the distal end of the catheter. The balloon is comprised of at least two materials of different elastic modulus, which allows for a flexible but relatively non-distensible, unfolding component of the balloon as well as an elastomeric, inflatable component of the balloon. Through the injection needle, an amount of cytotoxic, cytostatic, or anti-neoplastic agent is delivered to the target region. The delivered amount is effective to limit by a therapeutically beneficial amount recurrent bronchial occlusion due to recurrence of the bronchial carcinoma. | 04-30-2015 |
20150126961 | Dispense Interface for an Ejection Device - The invention inter alia relates to a dispense interface for an ejection device. The dispense interface comprises at least two inlets, at least one outlet and a part having multiple portions; wherein the multiple portions are connected by living hinges such that the multiple portions are foldable towards each other; wherein the multiple portions are configured to form a fluid channel arrangement between functional surfaces of the multiple portions facing each other when the multiple portions are folded towards each other; wherein at least two functional surfaces of the functional surfaces are inclined to each other when the multiple portions are folded towards each other; and wherein the fluid channel arrangement is configured to provide fluid communication between the at least two inlets and the at least one outlet. | 05-07-2015 |
20150126962 | TISSUE PENETRATION DEVICE - An agent injection device is provided that is capable of injecting an agent to a known predetermined tissue depth. An injection member has an elongate injection shaft with an outlet port configured to dispense an agent at a controllable time. A controllable driver is coupled to the elongate injection shaft and is configured to drive the injection member into target tissue. A velocity control system is in communication with the controllable driver and is configured to control the velocity of the elongate injection shaft. | 05-07-2015 |
20150126963 | INJECTION DEVICE CONFIGURED TO MATE WITH A MOBILE DEVICE - Injection systems powered, controlled and network-enabled by a mobile device, and methods for powering and controlling an injection system using a mobile device, are disclosed. An injection device includes a fluid container having a fluid container exit port, an injection driving element adapted to displace fluid from the fluid container through the fluid container exit port, and a connection module connected to the injection driving element, connectable to a mobile device, and adapted to receive electrical power or injection input data from the mobile device. | 05-07-2015 |
20150133890 | OCCLUSION DETECTION - A system for occlusion detection could include a syringe pump for a syringe containing a medication, wherein the syringe includes a plunger and the syringe pump includes a plunger driver. A bendable element could be integrally formed with the plunger driver, and a force sensor could also be integrally formed with the plunger driver. Upon occurrence of an occlusion, the plunger would exert a force backwardly against the bendable element, thereby deflecting the bendable element into contact with the force sensor to thereby generate a signal indicating the occurrence of the occlusion. | 05-14-2015 |
20150141954 | DEVICE FOR INSERTING NEEDLES - A device for inserting at least one hollow needle for the injection or withdrawal of a solution into/from a tissue, said device comprising a casing ( | 05-21-2015 |
20150141955 | INFUSION PUMP AUTOMATION SYSTEM AND METHOD - An infusion pump automation system and method includes an infusion pump, an infusion pump and a remote processor. The remote processor is remote to the infusion pump and includes a controller interface and a controller, such that the controller bidirectionally communicates with the infusion pump, determines a current infusion state of the infusion pump and a current infusion pump user interface state and accepts a command to change the infusion state of the infusion pump from an external server. The controller determines if the command is consistent with the current infusion state of the infusion pump and the current infusion pump user interface state, executes the command if the command is able to be successfully executed, and confirms that the command is successfully executed. | 05-21-2015 |
20150141956 | MULTI-BARREL SYRINGE INJECTION SYSTEM - An injection device for injecting a medicant into a plurality of tissue sites in a patient for a selected treatment is constructed and arranged such that the number of tissue sites is the total number for the selected treatment thereby requiring a single positioning step. The injection device includes a body having a syringe and a control linkage, the syringe including a plurality of barrels, and a cooperating plunger array including a plurality of plungers. Each barrel receives a corresponding plunger. The injection device further includes a plurality of injection needles connected to the syringe wherein one injection needle is connected to each barrel, a multi-lumen tip, a shaft connected to the multi-lumen tip and extending between said multi-lumen tip and said body. The control linkage is connected to each needle so as to move each needle between a deployed injection position and a retracted position. | 05-21-2015 |
20150148775 | DRUG DELIVERY DEVICE WITH RETAINING MEMBER - A drug delivery device is provided for delivering a drug to a target tissue site. The drug delivery device comprises a body comprising a proximal end and a distal end and a chamber disposed therebetween. An upper portion is disposed about the proximal end of the body. A retaining member is disposed within a wall of the body and engageable with the chamber and a plunger is configured for disposal within the upper portion and the chamber. The upper portion is movable about the proximal end of the body to open the chamber such that the plunger is disposed within a passageway defined within the chamber, and movement of the plunger in a distal direction pushes the retaining member such that the drug moves out of the body. Methods are also disclosed. | 05-28-2015 |
20150148776 | PERITONEAL DIALYSIS CONNECTION SYSTEM AND METHOD FOR USING ULTRAVIOLET LIGHT EMITTING DIODES - Peritoneal dialysis systems and methods are provided by the present disclosure. In a general embodiment, a peritoneal dialysis system includes a peritoneal dialysis fluid supply, a supply line in fluid communication with the peritoneal dialysis fluid supply, the supply line terminating at a supply connector, a patient connector in fluid communication with a patient's indwelling catheter, and a device configured to be placed around at least one of the supply connector and the patient connector during a connection of the supply connector and the patient connector, the device including an ultraviolet (“UV”) transmissive material to allow UV energy to be directed inwardly through the device towards a mating surface of the at least one of the supply connector and the patient connector during the connection of the supply connector and the patient connector. | 05-28-2015 |
20150148777 | HYDRAULIC DEVICE FOR THE INJECTION OF BONE CEMENT IN PERCUTANEOUS VERTEBROPLASTY - The present invention relates to the medical field, in particular relates to the practice of percutaneous vertebroplasty where a pair of syringes in the distal extreme of a lengthened hydraulic device, are united by a camera of intermediate connection of larger diameter (pressure exerting body) or modified inverted syringe tube with a bolster, a hydraulic connecting tube of flexible material that transmits the pressure of the smaller diameter manual or impulsion syringe in the proximal extreme of the device toward the intermediate cylindrical larger diameter camera (pressure exerting body), this camera is in an inverted position with regard to the first syringe (fluid control), this intermediate camera has a moving piston longitudinal to the axis of the cylinder that is controlled with the first syringe (manual) and in cooperation with the atmospheric pressure. The injecting syringe loaded with bone cement is coupled with the bolster of the body of pressure, and to the needle that drives the cement toward the interior of the bone. The intermediate camera (pressure exerting body) together with the hydraulic tube and the manual syringe form a hydraulic press system (F/A=f/a) that allows to increase in a potential way the pressure exerted in the first syringe and to make the injection of polymethylmethacrylate (PMMA) at an approximate distance of 1.0 m to 1.5 m. | 05-28-2015 |
20150289927 | Method and Apparatus For Dermatological Treatment and Tissue Reshaping - The present invention provides improved methods and apparatus for skin treatment and tissue remodeling. The apparatus includes an array of needles that penetrate the skin and serve as electrodes to deliver radio frequency current or other electrical or optical energy into the tissue being treated, causing thermal damage in controlled patterns. The damaged regions promote beneficial results such as uniform skin tightening by stimulation of wound healing and collagen growth. | 10-15-2015 |
20150290401 | PROTECTIVE INJECTION AID - The present aids and their attendant methods allow injectors to achieve injection and sampling using syringes with reduced danger of incurring accidental needle punctures upon themselves. Injection aids feature a needle cap receptacle as part of the aid such that a needle may be uncapped, the cap being retained on the injection aid. In accordance with present methods, a fold of skin may be created with the aid in order to facilitate insertion of the needle. The used needle may thereafter be inserted into the protective cap while that cap is retained on the injection aid, rather than being held in the fingers of the injector. Kits are also provided comprising the injection aids of the invention. | 10-15-2015 |
20150297829 | INJECTABLE DRUG DELIVERY ARRANGEMENT WITH CONTROLLED DELIVERY CANNULA POSITION RELATIVE TO POINT OF DELIVERY - A cannula for administration of a medicine to a target location includes a tube with at least one nodule disposed along the circumferential surface and spaced at a defined distance from the distal end of the tube. An arrangement for delivery of a medicine to a target location includes the cannula and a pump fluidly coupled to the cannula. The distal end of the cannula may be inserted into a target location until the nodule reaches a surface that limits a depth of penetration before delivery of the medication. | 10-22-2015 |
20150306318 | APPARATUS AND METHOD FOR IMPROVED MEDICATION DOSING - An apparatus and method for improving medication dosing is provided. The apparatus preferably includes a template configured to fit over a barrel of a syringe, the template having a substantially opaque exterior and at least one substantially transparent section in the substantially opaque exterior permitting a view of the syringe barrel and a distal end of a plunger within the barrel of the syringe. A method includes the steps of positioning a dosing template on a syringe, operating a plunger within the syringe, and drawing a predetermined dose of medication into the syringe. | 10-29-2015 |
20150306350 | Anchoring Nerve Block Catheter - The invention relates to medical devices and, particularly, catheter medical devices. In an aspect is a nerve block catheter system comprising a dual-sheath catheter comprising an inner sheath and an outer sheath, wherein distal ends of the sheaths are connected, the inner sheath defines a fluid delivery lumen, and the outer sheath comprises a tissue lock movable between a collapsed position and an extended position, wherein the tissue lock forms a reversible tissue anchor when in the extended position, and an actuator connected to the proximate end of the catheter and configured to activate the tissue lock by sliding the outer sheath length-wise relative to the inner sheath. | 10-29-2015 |
20150314064 | IMPLANTABLE DRUG-DELIVERY DEVICES, AND APPARATUS AND METHODS FOR FILLING THE DEVICES - In various embodiments, a tool is employed in filling a drug-delivery device. The tool may include, for example, a needle that is admitted through a fill port of the drug-delivery device. | 11-05-2015 |
20150320931 | LIQUID MEDICINE INJECTION DEVICE, CONTROLLER, LIQUID MEDICINE INJECTION SYSTEM, AND CONTROL METHOD - A liquid medicine injection device is controlled by a controller. The liquid medicine injection device includes: a liquid medicine injection unit; a first communication unit which communicates with the controller; and a control unit which switches off the communication by the first communication unit while the liquid medicine injection unit is injecting a liquid medicine. Communication between the liquid medicine injection device and the controller is carried out securely. | 11-12-2015 |
20150320942 | DISPENSE INTERFACE - The invention relates to a dispense interface comprising a body comprising at least a first channel structure and a second channel structure, wherein each of the at least two channel structures comprises at least a first inlet channel comprising a first inlet opening and a second inlet channel comprising a second inlet opening, wherein each of the at least two inlet openings of one channel structure is configured for fluid communication with a respective reservoir of at least two reservoirs and wherein at least one connecting channel configured for a fluid communication between at least one outlet opening and one of the at least two channel structures is provided. | 11-12-2015 |
20150328444 | Capillary injection needle - Apparatus for the repeated injection of substances into an organic skin, with a housing ( | 11-19-2015 |
20150335351 | LOW PROFILE INTRODUCER APPRATUS - An introducer apparatus includes an outer sleeve and an inner cannula received within the lumen of the outer sleeve. The outer sleeve has a profile such that at least a portion of the distal end of the outer sleeve tapers in the distal direction at an angle not exceeding about 2° relative to a longitudinal axis of the apparatus. The distal open end of the outer sleeve has a wall thickness not exceeding about 0.003 inch. The inner cannula includes a tapered distal end portion. The tapered distal portion of the inner cannula extends distal to the distal open end of the outer sleeve, such that a generally smooth diametrical transition is provided between the outer sleeve tapered portion and the open distal end of the inner cannula. | 11-26-2015 |
20150335825 | DRUG DELIVERY DEVICE WITH FRONT LOADING FEATURE - A drug delivery device adapted to receive a cartridge and hold it in a mounted position is provided, comprising a housing, an expelling assembly, and a front-loaded cartridge holder assembly adapted to receive and hold a cartridge in a mounted state. The assembly comprises cartridge holding means actuatable between a receiving state and a holding state, as well as a user operated actuation sleeve being rotationally actuatable relative to the housing between a loading state and an operational state, such that the cartridge holding means is actuated from the receiving state to the holding state when the actuation sleeve is actuated from the loading state to the operational state. The actuation sleeve is configured to enclose at least a portion of a mounted cartridge and is provided with inspection means allowing at least a portion of an enclosed cartridge portion to be visually inspected. | 11-26-2015 |
20150342635 | POSITIONING AND TISSUE SENSING DEVICES AND METHODS - A positioning device with sensing capacities is provided, which facilitates needle or catheter introduction into a body tissue or cavity and is configured to sense the types of encountered tissue. Using the epidural access procedure as an example, device and method designs are presented, which enable the sensing of needle entrance to the epidural space and anchoring of the cannula within the ligamentum flavum tissue to prevent puncturing of the dura mater. In case of tissue sensing by an expandable balloon, balloon fluid pressure and volume are used to indicate tissue and cavity characteristics encountered during the procedure. Device embodiments, device construction methods and treatment methods are provided. | 12-03-2015 |
20150343147 | INJECTION DEVICE - Disclosed herein are devices and methods that can provide assistance with extruding and/or aspirating high viscosity materials such as dermal fillers. | 12-03-2015 |
20150343157 | MEDICATION INJECTOR WITH NEAR-EMPTY ALERT - A medication injector that has an alert indicator that alerts the user when the medication injector is approaching near the end of its medication supply is disclosed. The alert indicator gives the user an opportunity to make preparations to obtain additional medication for the injector if there is an insufficient amount of medication in the injector to enable the user to dispense the required dosage amount with the next injection. Initially, the alert indicator is not visible to the user, but becomes visible to the user when the injector is near empty. | 12-03-2015 |
20150352293 | INJECTION DEVICE FOR MINIMALLY INVASIVE PROCEDURES AND USES THEREOF - Provided herein is an injection device that can be used in minimally invasive procedures, such as laparoscopic surgeries, for direct administration of a fluid, such as a therapeutic, to a target tissue or organ. | 12-10-2015 |
20150352294 | SYRINGE PUMP ENGAGEMENT DETECTION APPARATUS AND METHODS - Syringe pump apparatus and methods for detecting proper or improper engagement of a syringe pump drive system with a syringe in the syringe pump are disclosed. The apparatus and methods can determine proper or improper engagement between a drive system and the plunger of a syringe in a syringe pump by detecting the force required to move a plunger clip in reverse while restricting flow into the syringe. The apparatus and methods may also be used to determine that a syringe in the syringe pump apparatus is properly connected to a delivery line. | 12-10-2015 |
20150352296 | DEVICE, A SYSTEM AND A METHOD FOR IDENTIFICATION/AUTHENTICATION OF PARTS OF A MEDICAL DEVICE - Disclosed is a dispensing system. The dispensing system includes a dispensing unit to dispense therapeutic fluid, and a validation mechanism to enable operation of the dispensing unit based, at least in part, on a determination of whether operation of the dispensing device is authorized. | 12-10-2015 |
20150359960 | User-Actuated Storage Assembly For Injection Device - A storage assembly is removably connectable to a drug delivery device. A first chamber is disposed in the housing. A plurality of penetrating members are stored in the first chamber. A second chamber is disposed in the housing for storing the plurality of penetrating members after being used in an injection. A transfer drum disposed in the housing transfers one of the penetrating members from the first chamber to an injection position and from the injection position to the second chamber following an injection. | 12-17-2015 |
20150359966 | SYSTEM FOR MONITORING AND DELIVERING MEDICATION TO A PATIENT AND METHOD OF USING THE SAME TO MINIMIZE THE RISKS ASSOCIATED WITH AUTOMATED THERAPY - A system and method for monitoring and delivering medication to a patient. The system includes a controller that has a control algorithm and a closed loop control that monitors the control algorithm. A sensor is in communication with the controller and monitors a medical condition. A rule based application in the controller receives data from the sensor and the closed loop control and compares the data to predetermined medical information to determine the risk of automation of therapy to the patient. A system monitor is also in communication with the controller to monitor system, remote system, and network activity and conditions. The controller then provides a predetermined risk threshold where below the predetermined risk threshold automated closed loop medication therapy is provided. If the predetermined risk threshold is met or exceeded, automated therapy adjustments may not occur and user/clinician intervention is requested. | 12-17-2015 |
20150360004 | Over-the-Needle Expandable Catheter - The present disclosure is directed to an over-the-needle (OTN) catheter assembly having an expandable catheter. More specifically, the OTN catheter assembly includes a catheter having an expandable body with a proximal end and a distal end coaxially mounted onto a needle. The body defines a lumen extending from the proximal end to the distal end. Further, the body is expandable between a compressed length and an expanded length. The needle is configured within the lumen of the catheter and has a first length. The first length is longer than the compressed length of the catheter and shorter than the expanded length of the catheter. In addition, the body of the catheter is configured to expand from the compressed length to the expanded length when heat is applied to the catheter such that the distal end of the catheter extends past a distal end of the needle. | 12-17-2015 |
20150360018 | Drug Delivery Device - A drug delivery device is disclosed that may include a skin penetrating assembly having a support defining an upper surface and a lower surface. The skin penetrating assembly may also include a plurality of skin penetrating members extending outwardly from the lower surface. Each skin penetrating member may define a channel for receiving a drug formulation. In addition, the device may include a reservoir positioned adjacent to the upper surface of the support for initially retaining the drug formulation. The reservoir may include a top surface and a bottom surface and may define a plurality of passages extending between the top and bottom surfaces. The passages may be configured such that the drug formulation is retained within the passages against gravity. | 12-17-2015 |
20150367066 | Medicine Delivery Device Having Detachable Pressure Sensing Unit - A fluid medicament delivery device includes a patient attachment unit and a separate indicator unit. The patient attachment unit includes a housing and a fluid channel located therein, wherein at least a portion of the fluid channel includes a flexible member substantially coterminous with the housing. The separate indicator unit is adapted to be detachably coupled to the housing of the patient attachment unit and includes a first sensing element for contacting the flexible member when the indicator unit is coupled to the housing to sense a flexure of the flexible member. | 12-24-2015 |
20150367070 | Empty Infusion Supply Container Annunciator and Detection Method - A medical fluid infusion system includes a pump system configured to deliver a fluid drug to a patient. The system includes a device and method for detecting when the level of a fluid in a fluid supply container (such as an IV bag) is exhausted or near exhausted. | 12-24-2015 |
20150367101 | TIP PROPELLED DEVICE FOR MOTION THROUGH A PASSAGE - A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, the end ones of which expand at least radially when inflated. Connecting passages provide fluid communication between each pair of adjacent chambers. A fluid source is attached to one of the end chambers. The connecting passages are such that the fluid inflates the chambers in a sequence, beginning with the chamber closest to the source, and ending with the chamber furthest from the source. The same sequence occurs when the chambers deflate, beginning with the chamber closest to the source, and ending with the chamber furthest from the source. The fluid source can either be a fluid supply tube, extending to a supply outside the lumen, or it can be built-in and carried by the device. The device can crawl either along the lumen wall or on an inserted guide wire. | 12-24-2015 |
20150367105 | SHEATH WITH SENSING CAPABILITIES - Disclosed are sheaths that comprise a first sheath member having a first passageway, a first length, and a first proximal end defined by a first valve apparatus configured to seal the first passageway, the first passageway having a first passageway diameter at a location in the first passageway; and a second sheath member coupled to the first sheath member, the second sheath member having a second passageway and a second length, the second passageway having a second passageway diameter at a location in the second passageway; where the first passageway and the second passageway are separate from each other and not co-axial, the first length is different from the second length, and the first and second sheath members are positioned beside each other for a portion of their first and second lengths. | 12-24-2015 |
20150367117 | Transdermal Drug Delivery Device - A transdermal drug delivery device is disclosed that may comprise a housing including an upper housing portion and a lower housing portion. The lower housing portion may define a bottom surface including skin attachment means for releaseably attaching the lower housing portion to skin of a user. The upper housing portion may at least partially surround a central region of the device. The device may also include a microneedle assembly and a reservoir disposed within the central region. The reservoir may be in fluid communication with the microneedle assembly. Additionally, the device may include a pushing element disposed above the microneedle assembly within the central region. The pushing element may be configured to provide a continuous bilateral force having a downward component transmitted through the microneedle assembly and an upward component transmitted through the skin attachment means. | 12-24-2015 |
20150374587 | BARIATRIC DEVICE AND METHOD - A bariatric device and procedure configured to control the amount of food and nutrients entering a person's duodenum and reduce the weight of the person, in one aspect, comprises a gastrostomy tube having a proximal end and a distal end; a feeding tube assembly, said assembly including a feeding tube having a proximal end and a distal end; a gastrostomy tube anchor for securing the distal end of said gastrostomy tube inside the stomach; and a first feeding tube anchor designed to be expanded after the pyloric sphincter so as to anchor the distal end of said feeding tube in the duodenum. | 12-31-2015 |
20150374908 | MRI-Compatible Surgical Cannulae for Transferring a Substance to and/or from a Patient - A cannula for transferring a substance to and/or from a patient includes a tubular support sleeve and a transfer tube. The support sleeve includes a rigid tubular member defining a lumen extending from a proximal end to a distal end of the tubular member. The transfer tube is positioned in the lumen and extends beyond each of the proximal end and the distal end of the tubular member. The tubular member includes a rigid, MRI-compatible material. | 12-31-2015 |
20150374918 | SELECTABLE SINGLE DOSE AUTO-INJECTOR AND METHODS OF MAKING AND USING SAME - An auto-injector device for administering a liquid pharmaceutical composition, in which an end-user can select between doses that the device is capable of delivering. The end-user choices that translate into the selected doses can be based on end-user perceived severity of symptoms, end-user weight and other such factors. In some embodiments the auto-injector is configured to administer the one chosen dose only. In other embodiments, the auto-injector can deliver second and subsequent doses up to full dose of the pharmaceutical composition disposed in the injector. The auto-injector can provide visual, audio, and tactile feedback, alone or in combination, to the user to indicate the dose selected, instructions for use, and when the dose has been administered. | 12-31-2015 |
20150374923 | METHOD AND APPARATUS FOR CONTROLLING THE DISCHARGE RATE OF A SYRINGE - A method and apparatus for use in controlling a dispensing rate of medication or other substance via a syringe, including, without limitation, into a patient, intravenous line port or heparin lock. A force (typically manual) is applied to an input plunger of a dashpot, which is directly coupled to a piston which, in turn, is coupled to an output plunger. The force applied to the input plunger is buffered and transmitted to the output plunger. The output plunger acts upon the plunger of a conventional syringe, thereby resulting in flow of medicine or any other substance from the syringe at a desired and controlled flow rate. | 12-31-2015 |
20150374954 | METHOD OF PROVIDING POST OPERATIVE EPIDURAL ANALGESIA IN SPINAL SURGERY - A method of placing spinal epidural catheters prior, during or after spinal surgery is provided. The method may include an epidural catheter tunneled externally down an epidular space above the operative site so as to continuously infuse analgesic solution through the catheter into a predetermined site. | 12-31-2015 |
20160000996 | APPARATUS FOR RECEIVING A SYRINGE IN A FLUID-DISPENSING APPARATUS AND A METHOD FOR SAME AND USE OF SUCH A RECEPTACLE - The invention relates to a device and a method for receiving of a syringe in a fluid-dispensing apparatus without play, said apparatus having at least two elastically prestressable clamping means which grip the plunger flange of a syringe, such that an elongated hole is provided for each clamping means, the clamping means sliding in the elongated hole and thus executing a rotational movement and a translatory movement at the same time during the gripping operation. In addition, the invention relates to a method for doing so and a device having such an apparatus. | 01-07-2016 |
20160001007 | DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE - A drive mechanism for a drug delivery device having a rotationally fixed plunger rod driven by a lead screw. The lead screw engages a free lock which is coupled to a release knob. A dose setting dial cooperates with an inner cylinder using a clutch to establish the axial movement of the plunger rod during dose setting and dispensing. | 01-07-2016 |
20160001009 | DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE - A drive mechanism for a drug delivery device having a rotationally fixed plunger rod driven by a lead screw. The lead screw engages a free lock which is coupled to a release knob. A dose setting dial cooperates with an inner cylinder using a clutch to establish the axial movement of the plunger rod during dose setting and dispensing. | 01-07-2016 |
20160008541 | SUBSTANCE DISPENSING DEVICE WITH SIGNALING DEVICE | 01-14-2016 |
20160008544 | FLUID DELIVERY DEVICE AND METHOD | 01-14-2016 |
20160008545 | LOW WASTE SYRINGE AND NEEDLE ASSEMBLAGE | 01-14-2016 |
20160008546 | ADD-ON GRIP AND ACTUATION-SLEEVE FOR A PEN-TYPE DRUG INJECTION DEVICE | 01-14-2016 |
20160008552 | Dose Capturing Cartridge Module for Drug Delivery Device | 01-14-2016 |
20160008556 | NEEDLE INSERTION SYSTEM AND METHOD FOR INSERTING A MOVABLE NEEDLE INTO A VERTEBRATE SUBJECT | 01-14-2016 |
20160015423 | EXCHANGER SURGICAL ACCESS PORT AND METHODS OF USE - A surgical instrument access port assembly and method of use, the surgical instrument access port a surgical instrument has a needle lumen and a surgical access port. The needle lumen extends in a longitudinal direction and includes a needle tip at a distal end, and a body portion at a proximal end, the body portion having at least one recess or finger. The surgical access port has a cannula defining a hollow cannula shaft, and a tapered hub attached to a proximal end of the cannula. The tapered hub includes at least one inner ring configured to abut against the at least one recess or finger while the surgical instrument is inserted into the cannula of the surgical access port. | 01-21-2016 |
20160015755 | SPINAL DISK REGENERATIVE COMPOSITION AND METHOD OF MANUFACTURE AND USE - The present invention provides a novel way to replenish the disc using retooled disc compositions to repair degenerative discs. There is no better source of proteoglycans than the actual disc material ( | 01-21-2016 |
20160015904 | Drug Delivery Device and Method for Eliminating a Clearance of the Piston Rod for Drug Delivery Devices - The piston rod arrangement is in an assembled state before use and comprises a piston rod, a bung, which is intended to be driven by the piston rod, a body member, and a drive member. The piston rod is threadedly engaged with the body member, and the drive member is threadedly engaged with the piston rod and movable relative to the body member. A mechanism is provided defining unit steps of movement of the drive member and corresponding unit steps of movement of the piston rod. The piston rod is arranged in contact with the bung or at a distance from the bung that is less than a distance of one corresponding unit step of movement. When the piston rod, the bung and the drive member are assembled in the body member, the piston rod is advanced with respect to the body member towards the bung, until the piston rod is stopped by the bung. The drive member is rotated until the piston rod begins to advance again and the drive member is then stopped, and the piston rod is fixed at or near the position obtained. | 01-21-2016 |
20160022312 | MODIFIED VERESS NEEDLE FOR TENSION PNEUMOTHORAX DECOMPRESSION - Disclosed are devices and methods for treating tension pneumothorax. A needle assembly may include an outer cannula defining a lumen and having a distal end portion with a sharp bevel, and an inner cannula slidably-disposed through the lumen of the outer cannula. The inner cannula moves between an extended and retracted position and includes a blunt distal end portion configured to extend beyond the sharp bevel of the outer cannula when the inner cannula is in the extended position. The blunt distal end portion can retract within the lumen of the outer cannula when the inner cannula is in the retracted position, thereby exposing the sharp bevel. The needle assembly further includes a bias disposed inside the housing and coupled to the inner cannula. A proximal end portion of the inner cannula is configured to extend through the housing when the inner cannula is in the retracted position. | 01-28-2016 |
20160022539 | A PREFILLED MEDICATION DEVICE, METHOD OF MAKING AND USING THE SAME - The invention generally relates to prefilled disposable medication devices, method of making, and using to store, contain and deliver at least a diluent for allergenic extract and more particularly to a prefilled cartridge containing a diluent for allergenic extract for use with an injection pen for allergy treatments. | 01-28-2016 |
20160022912 | SYSTEM FOR DELIVERING MEDICATION - Aspects of the present disclosure disclose a system for delivering medication. In one aspect, the disclosure is directed a medical dispensing device that includes a label with a series of zones of varying widths, with each of the zones corresponding to a pre-determined volumetric dose of the drug that is correlated to one of the physical characteristics of a patient. In one specific example, the label is further affixed to the medicine dispensing device such that the smallest dose of the drug to be administered corresponds to a first zone that is proximate an opening through which the drug is to be dispensed. | 01-28-2016 |
20160022920 | Syringe - A lock unit for a syringe provides a proper dose of an agent or medication from the syringe. The lock unit sets the dose of the syringe and is not thereafter affected by subsequent shipping or handling. The lock unit is applied to the plunger to limit the travel of the syringe piston in the syringe barrel thus limiting the dose that is delivered. Optionally, one or more syringes can be provided with a plurality of lock units of differing dimensions each set to deliver a specific dose of the agent when attached to a syringe. | 01-28-2016 |
20160022926 | Methods for Detecting Failure States in a Medicine Delivery Device - A fluid medicament delivery device includes a patient attachment unit, containing the fluid medicament, and an indicator unit adapted to be detachably coupled to the patient attachment unit. A method for monitoring the fluid medicament includes independently setting a flow rate of a fluid medicament with the patient attachment unit. A pressure and/or a flow rate of the fluid medicament is sensed with a sensor located in a separate indicator unit in a sensing mode. A status of the fluid medicament delivery device is determined based at least in part on the pressure and/or the flow rate. | 01-28-2016 |
20160022974 | DRUG DELIVERY DEVICE AND METHODS HAVING AN OCCLUDING MEMBER - Drug depot delivery devices and methods for delivering a drug depot to a site beneath the skin of a patient are provided. In various embodiments the device has a housing having a top housing end, and a bottom housing end. The housing defines a housing channel. The device has a drug cartridge defining a depot channel aligned with the housing channel and configured to slidably accept the drug depot. The drug cartridge has at least a first occluding device configured to occlude the depot channel at a first position such that the drug depot cannot pass through the depot channel without force applied to the drug depot sufficient to deflect the first occluding device. The bottom end of the housing has a coupling configuration for engaging a cannula. A plunger has a push rod to expel the drug depot through the occluding device and the cannula. | 01-28-2016 |
20160022975 | DRUG DELIVERY DEVICE AND METHODS HAVING A RETAINING MEMBER - Various embodiments of a device, a kit and method for delivering a drug depot are disclosed. The device comprises a housing including a lower body, an upper body, a ring member; and a drug cartridge. The lower body defines a lower body channel. The upper body defines an upper body channel. The drug cartridge defines a depot channel. The ring member is disposed extending upward from an annular step surface of the lower body toward a housing upper end. The ring member includes indicia indicating a characteristic of one or more drug depots in the drug cartridge. A plunger has a push rod for expelling the drug depot through the cannula to a site in the patient. A kit comprises the above components. A method includes assembling the components including selecting a ring member having indicia corresponding to one or more drug depots in the drug cartridge. | 01-28-2016 |
20160030107 | BLADDER TREATMENT BY ABLATIVE DENERVATION - In one aspect, the present disclosure is directed to methods of treating various conditions including bladder conditions in a patient, comprising: positioning at least one ablative element of an ablative device on or over an adventitial surface of the bladder; and using the ablative device to denervate bladder nerve fibers. Other aspects of the present disclosure pertain, for example, to devices and kits for of treating bladder conditions. | 02-04-2016 |
20160030293 | Vented Connector for Feeding Syringe - An enteral feeding connector includes a connector body that can be removably attached to a tip of a syringe, which has a component that makes a fluid tight seal with the syringe tip. An air venting stem integrally formed with the component can extend into a barrel of the syringe. An air venting passage extends through the air venting stem and opens in the barrel of the syringe. An enteral fluid passage extends through the component and is in fluid communication with the barrel of the syringe. | 02-04-2016 |
20160030677 | Injection System - Methods and systems for an injection system are provided. An example injection system includes a container for a pharmaceutical that is sealed at a proximal end with a plunger having a pushing surface for engaging an inner surface of the hollow body. A plunger rod extends axially from the proximal end of the container and is covered with a plunger rod cover. Removal of the cover activates the system and allows for delivery of the pharmaceutical product from the container by advancing the plunger within the container towards the seal. | 02-04-2016 |
20160030685 | DEVICE FOR REDUCTION OF NEEDLE INSERTION SITE PAIN IN PATIENTS - Various embodiments of the present invention are directed to a device for the reduction of needle insertion site pain in patients. Various embodiments comprise a shell defining a hollow interior cavity filled at least in part by a freezable substance. The shell defines a first surface and a second surface opposite the first surface, and a passage extending through the shell between the first surface and the second surface, wherein the passage is configured to at least partially surround a needle insertion site while a needle is inserted therethrough. At least one of the first and second surfaces comprise a plurality of protrusions distributed therein and configured to be depressed into the skin of the patient. When chilled and depressed against the patient's skin, the freezable device provides a sensory confusion sensation to the patient, thereby reducing perceived pain caused by the needle insertion. | 02-04-2016 |
20160030728 | EXTRUDABLE TUBING AND SOLVENT BONDED FITTING FOR DELIVERY OF MEDICINAL FLUIDS - Assembly, and method of fabricating an assembly including an extruded polymeric tube and a prefabricated tubular polymer body (fitment), the method including the steps of: extruding an outer tubular surface of a thermoplastic propylene-based elastomer (PBE) material; treating the outer surface along a selected axial length at one end of the tube with a solvent; inserting the treated one end into a hollow tubular passage of a prefabricated tubular body having an inner passage wall of a polypropylene-based material; and allowing the mated juncture to dry such that the treated outer surface solvent bonds to the inner wall. The tubing is preferably a coextruded tube having an innermost layer of a thermoplastic ethylene-based olefinic material. The mating tubing and fitment overcome the prior art problems of stress cracking, fluid contamination and/or processing difficulties. | 02-04-2016 |
20160038675 | INFUSION PUMP ASSEMBLY AND METHOD - Some embodiments of an infusion pump assembly may be equipped with one or more components to facilitate wireless operation of an infusion pump via a user-operated mobile device. In some embodiments, the mobile device and/or the infusion pump may prompt the user to confirm acceptance of a wirelessly communicated command to prevent an operation by the infusion pump (e.g., a dispensation of medicine) that is not desired by the user. | 02-11-2016 |
20160038678 | Auto-Injector - The invention refers to an auto-injector for administering a dose of a liquid medicament, comprising:
| 02-11-2016 |
20160045217 | METHODS AND DEVICES FOR LAPAROSCOPIC SURGERY - Two part laparoscopic tools and surgical methods using such tools are presented. The tools and methods enable use of multiple surgical tools each having wide tool heads to be used in a body cavity using a single wide trocar and one or more narrow incisions, thereby reducing surgical risk and enhancing patient comfort and shortening recovery time. Additional instruments for facilitating laparoscopic surgery are also presented. | 02-18-2016 |
20160045765 | SYSTEM AND METHOD FOR OPTOGENETIC THERAPY - Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells. | 02-18-2016 |
20160051755 | LOW COST FLUID DELIVERY DEVICE - Embodiments of the invention described herein include low cost infusion devices having basal and/or bolus fluid delivery options. Embodiments of the device include a housing, a reservoir to contain the fluid, a source of pressure to exert a force to expel the fluid contained in the reservoir, a bolus port adapted to receive an optional extra dose of fluid, and a cannula in fluid communication with the reservoir and the bolus port. The cannula is adapted for insertion into the user's skin for delivery of the fluid to the user's body. The device can provide a continuous delivery of the fluid along a first fluid flow path from the reservoir to the cannula and the optional extra dose of fluid along a second fluid flow path from the bolus port to the cannula. | 02-25-2016 |
20160058945 | Injection Device with Audio Output - A medical injection device and associated methods of use are disclosed which facilitate the self-administration of injectable medicine by a user who is visually impaired. In an aspect, the medical injection device and associated methods assist a visually impaired user by providing a speaker attached to the injection device that communicates audibly with a user the size of the dosage of medicine the device is currently set to administer, as well as what amount of medicine is currently available within the device. | 03-03-2016 |
20160067406 | Modular Apparatus for Delivery of Fluid Materials - Apparatuses and methods for delivery of fluid materials, particularly multi-part fluid materials, including modular apparatuses in which various components are maintained separately until ready for use. Each fluid component is maintained in a separate housing until mixing of the fluid components is desired. Maintaining components separately until use allows for proper filling, sterilization, packaging and storing until use. | 03-10-2016 |
20160074213 | INJECTOR APPARATUS - The devices and methods described herein relate to injector devices for delivering payloads to a tissue. | 03-17-2016 |
20160074597 | HEAT-CURLING POLYMERIC NEEDLE FOR SAFE DISPOSAL - A needle having shaft that forms a tip and a portion proximate to the tip that is formed from a shape memory polymer. The shaft of the needle may be programmed to curl from a straight configuration to a curved configuration upon triggering by heat, thereby moving the sharp tip and providing a non-stick needle for safe and easy disposal. | 03-17-2016 |
20160082242 | MICRONEEDLE INJECTION AND INFUSION APPARATUS AND METHOD OF USING SAME - A microneedle injection and infusion apparatus, and a method of using same. The apparatus ( | 03-24-2016 |
20160089495 | AUTOMATIC INJECTION DEVICE - A method for treating a disorder using an automatic injection device is disclosed. The device includes a syringe movably disposed in a housing and including a barrel portion, a needle and a bung for sealing the barrel portion. The device includes a syringe actuation component for moving the syringe towards a first open end of the housing such that the needle projects from the first end, and for subsequently applying pressure to the bung. The syringe actuation component includes a pressurizer, a rod comprising a compressible portion projecting therefrom, and a flange between a second end of the rod and the compressible portion. The device also includes a biasing mechanism for biasing the syringe actuation component towards the first open end of the housing, the biasing mechanism disposed about the second end of the rod between the flange and a second end of the housing. | 03-31-2016 |
20160089501 | Frontloaded Drug Delivery Device with Dynamic Axial Stop Feature - Drug delivery device adapted to receive a cartridge and comprising a housing, a front-loaded cartridge holder adapted to receive and hold a cartridge in a loaded position, and stop means adapted to engage a proximal surface of a received cartridge The stop means is actuatable between a receiving state in which the stop means is positioned in a first axial position thereby defining how far proximally a received cartridge can be inserted, and an operational state in which the stop means allows an inserted cartridge to be moved axially to a second more proximal position. | 03-31-2016 |
20160089502 | MULTIPLE DOSE SYRINGE AND METHOD - A multiple dose syringe has a first valve defining a first valve opening pressure and a second valve defining a second valve opening pressure. A storage chamber in fluid communication with the second valve stores multiple doses of a substance therein and includes an outlet for dispensing multiple doses of the stored substance therethrough. A compression surface is movable between first and second positions and defines a compression chamber between the compression surface and the first valve. Movement of the compression surface in a direction from the first position toward the second position dispenses substance in the compression chamber through the first valve and out of the syringe. Movement of the compression surface in a direction from the second position toward the first position causes substance to flow from the storage chamber through the second valve and into the compression chamber. | 03-31-2016 |
20160089503 | PALM ACTIVATED DRUG DELIVERY DEVICE - A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position. | 03-31-2016 |
20160089527 | Microneedle Roller (MNR) Infusion System - A micro-needle roller (MNR) infusion system for transdermal delivery of active agents, skin-care products, and other topical formulations is described herein. The infusion system of the instant invention comprises a needle roller assembly with needles enclosed in a housing with a vacuum line and a disposable cartridge having the active agent, the skin-care product or the topical formulation. The vacuum delivers the fluid and ensures that the skin is being pulled against the needle wheel surface to ensure that penetration of the needles is complete into the skin, simultaneously the fluid is flowing to the wheel and to skin as it rolls along with the outer housing of the tip cap assembly being occluded to the skin surface. | 03-31-2016 |
20160095984 | DEVICES FOR INJECTION AND DOSING - Injection devices are provided which include a handpiece capable of housing a cartridge containing an injectable composition, and a head coupled to the handpiece and housing a plurality of retractable needles and a dosing mechanism. Methods of treating skin surfaces are also provided. | 04-07-2016 |
20160101237 | INDICATION MECHANISM FOR AN AUTOMATIC APPLICATOR, PARTICULARLY FOR INSULIN - The present disclosure concerns an indication mechanism for an automatic applicator, particularly for insulin or other liquid preparations, particularly for multiple injection administration of set doses of a medicine from an exchangeable container, for example for the self-application of insulin by diabetes patients. An indication mechanism for an automatic applicator, having an assembly of at least two barrels movably coupled to each other has an indication barrel mounted on the driving barrel contains only marking on its external surface and is co-axially connected to the pull-push control nut. | 04-14-2016 |
20160101240 | NEEDLE FOR DELIVERING TREATMENT FLUID TO AN AVIAN BIRD, AND ASSOCIATED ASSEMBLY AND METHOD - A needle for delivering a treatment fluid to a target site of an avian bird is provided. Such a needle includes a shaft defining a longitudinal axis and having a proximal end and a distal end. Discrete grooves are defined by the shaft and extend partially along a length thereof. A needle tip extends from the shaft at the distal end thereof. A reservoir assembly includes a body defining first and second holes for receiving the needle therethrough such that the body supports the needle along the length thereof. The reservoir assembly defines a reservoir adapted to receive a treatment fluid through which the grooves pass to carry the treatment substance to the target site. An associated assembly and method are also provided. | 04-14-2016 |
20160101242 | SYSTEM AND METHOD FOR DIFFERENTIATING CONTAINERS IN MEDICATION DELIVERY - The present invention relates to a fluid delivery system that comprises a fluid container having a chamber structured to hold a fluid therein and a delivery device operable to control delivery of a fluid from the chamber of the fluid container. The fluid container includes a geometric mating member extending from an outer surface thereof. The delivery device includes a geometric mating receptacle structured to mate with at least a portion of the geometric mating member of the fluid container to verify compatibility of the fluid container with the delivery device. Alternatively or additionally, the fluid container may include a first data fixture component and the delivery device may include a second data fixture component that cooperates with the first data fixture component of the fluid container to verify compatibility of the fluid container with the delivery device. | 04-14-2016 |
20160106462 | Bone Marrow Aspiration Device And Method - A bone marrow aspiration device and related method includes an introducer assembly and an aspiration assembly to couple to the introducer assembly. The introducer assembly includes an introducer cannula having a proximal end and a distal end. The introducer cannula defines a lumen between the distal and proximal ends, the distal end being configured to penetrate bone of a patient. The aspiration assembly includes an aspiration cannula that is receivable in the lumen of the introducer cannula and that extends beyond the distal end of the introducer cannula. The aspiration cannula includes a port to aspirate bone marrow, the port being distal to the distal end of the introducer cannula. The aspiration device further includes a mechanism at the introducer assembly to move the introducer cannula and the aspiration cannula in tandem relative to a distal end of the mechanism when the aspiration cannula is positioned within bone. | 04-21-2016 |
20160106579 | INFUSION DEVICE AND METHOD - An ophthalmic infusion support and associated methods are shown. Example infusion support devices include a base unit, a fixation device coupled to the bottom surface of the base unit, and an infusion tube holding device configured to hold a loop of an infusion tube an angle projecting upward from the patient. | 04-21-2016 |
20160106587 | OCULAR GELS OR HYDROGELS AND MICROINJECTORS - Devices and materials for treating an ophthalmic pathology affecting an eye of a patient comprising forming, in situ, a continuous cohesive layer of covalently-crosslinked hydrogel at a choroid in the eye, wherein the hydrogel comprises a therapeutic agent that is released into the eye to treat the ophthalmic pathology. An injection device for injection into a tissue, for example an eye, comprising a syringe, and a needle, with the syringe comprising a reservoir in fluid communication with an outlet and a piston for expelling contents of the reservoir from the syringe through the outlet. An embodiment provides for setting or using a force for moving the piston so as to deliver the contents at, for instance, a suprachoroidal location. | 04-21-2016 |
20160106924 | INJECTION DEVICE - An injection device for delivering an injection comprises a housing having a longitudinal axis, a proximal end and a distal end, the housing being arranged such that the injection is delivered from its distal end; and a release mechanism comprising an impediment, the release mechanism being moveable between a first position, in which the impediment is in an impeding position so as to impede the delivery of the injection, and a second position, in which the impediment is in a non-impeding position so as to not impede the delivery of the injection, wherein the force required to move the release mechanism from the first position to the second position varies with the distance moved by the release mechanism, the variation in the force required with distance being represented by a force profile, which is non-linear. | 04-21-2016 |
20160106925 | SELF-CONTAINED MEDICATION INJECTION SYSTEM AND METHOD - A self-contained system for medication injection is activated by the user, who is able to distribute the medication through the self-contained needle system for intradermal or intramuscular application of the medication. The self-contained system may be a medication delivery pen having a pen body assembly comprising a distal end, a proximal end and a needle array containing a plurality of needles disposed within the pen body assembly. | 04-21-2016 |
20160106927 | Drug Delivery Device and System with Pre-Set Dose Feature - A drug delivery device comprises drug expelling means and a drug-filled cartridge, the cartridge comprising an outlet and an axially displaceable piston. The drug expelling means comprises a drive member adapted to engage and axially move the piston to thereby expel an amount of drug from the cartridge through the outlet, and a motor for moving the drive member. The device further comprises a display adapted to display a dose amount to be expelled, communication means allowing dose setting data to be received from an external device, and an electronic controller adapted to store received dose setting data, control the display, and control the motor to move the drive member to thereby expel an amount of drug corresponding to a set dose. | 04-21-2016 |
20160106932 | DEVICE AND METHOD FOR HINDERING FORMATION OF LIPOHYPERTROPHY - A device for rotating sites of subcutaneous injections into external tissue is provided. The device comprises a pad having an interlaced structure. The device further comprises a liquid disposed within the interlaced structure. The liquid is configured to leave a visible imprint onto the external tissue upon contact of the pad with the external tissue. | 04-21-2016 |
20160114107 | Frontloaded Drug Delivery Device with Actuated Cartridge Holder and Piston Rod Coupling - Drug delivery device adapted to receive a drug cartridge, comprising a cartridge holder, an expelling assembly with a piston rod and a coupling. The device further comprises user operated actuation means actuatable from a loading state to an intermediate state, and from the intermediate state to an operational state, wherein the cartridge holder is actuated from a receiving state to a holding state when the actuation means is actuated from the loading state to the intermediate state, and the coupling is actuated from a free resetting state to a locked operational state when the actuation means is actuated from the intermediate state to the operational state. | 04-28-2016 |
20160114110 | INFANT EPINEPHRINE AUTOINJECTOR - An injection device suitable for use with infants is disclosed. The injection device is formed from a body shield member and a cylindrical handle. The body shield member includes a concave flange at the base, which is pressed against the patient's limb and reduces local compression at the needle insertion site. The injection device also has a softer form and operates through a pressing motion. A catch member is located in the cylindrical handle, and is deployed upon fully depressing the handle. Once the handle returns to its starting position, the catch member prevents the handle from being depressed a second time and permitting the used needle to be exposed. | 04-28-2016 |
20160120587 | TRANSVASCULAR METHODS OF TREATING EXTRAVASCULAR TISSUE - An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand with open ends around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system also includes means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The preferred embodiment of the catheter includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall. | 05-05-2016 |
20160120694 | INJECTION INSTRUMENT AND METHOD - An injection instrument that includes a saddle configured to receive a syringe aligned on a saddle axis; a linear member coupled to the saddle at a sliding joint, the linear member having a first end and a second end, the sliding joint allowing relative movement between the linear member and the saddle in a direction aligned with a slide axis, the slide axis parallel with the saddle axis; and a guide member located at the second end, the guide member including an edge spaced apart from the saddle axis by a prescribed distance, the guide member including a tissue contact surface, wherein the tissue contact surface is located on a single side of the saddle axis. | 05-05-2016 |
20160121046 | ROTATABLE INFUSION SET - An arrangement for introducing a liquid into the body of a patient or for withdrawing a liquid from the body of a patient, including a first structural part carrying a cannula for positioning in the body of the patient, and a second structural part with a connection port for detachably coupling a conduit for supplying or withdrawing a liquid, wherein the first and second structural parts are connected, can be rotated relative to each another and in relative rotational positions form a channel for introducing a liquid from the conduit to the cannula or for withdrawing a liquid from the cannula to the conduit, and whereby movement of the conduit for coupling and uncoupling is transverse to the longitudinal axis of the cannula. | 05-05-2016 |
20160129183 | WIRELESS STRAIN GAUGE/FLOW SENSOR - A flow rate sensor is provided in a wireless, leadless package. The flow rate sensor includes a MEMs sensor coupled to an ASIC and an antenna. The flow rate sensor is powered by radiation received from a control module adjacent the flow rate sensor. The flow rate sensor is placed within a fluid and monitors the flow rate of the fluid. The control module is not in the fluid and receives flow rate data from the flow rate sensor. | 05-12-2016 |
20160129184 | DOSING METHOD WITH A DEVICE FOR TRANSFERRING AND DOSING BIOMEDICAL FLUIDS BETWEEN HOSPITAL CONTAINERS - A dosing method using a device for transferring and dosing biomedical fluids between hospital containers includes a syringe body containing a biomedical fluid and a piston sealed fitted therein, the syringe body including a first extremity having joining elements to a first container and to a second container, and a second extremity opposite the first extremity, the method including gripping a handle having a coupling seat for fastening to the second extremity; placing first temporary fastening elements between the coupling seat and second extremity; placing second temporary fastening elements between the piston and thrust rod; operating a thrust rod of a motorised element mounted in the handle for pushing the piston; and dosing using control elements mounted on the handle, associated with the motorised element to dose volumetric quantities of biomedical fluid from the first container and dispensing to the second container. | 05-12-2016 |
20160129185 | FIELD UPDATE OF AN AMBULATORY INFUSION PUMP SYSTEM - Portable or ambulatory infusion devices and systems capable of remotely updating an ambulatory fluid delivery device include safety protocols that verify the status of the ambulatory fluid delivery device before and after a field update of software. Methods of accomplishing the same field update of software are also described. | 05-12-2016 |
20160129192 | SYRINGE HAVING MULTIPLE LUMENS - A syringe can be used to receive fluid from a patient. The syringe can include a syringe body, a first lumen disposed within an internal space of the syringe body, a second lumen disposed within the internal space of the syringe body, and a plunger slideably received along an internal surface of the second lumen. The syringe can also include a stem elongate along a first direction, a handle coupled to the stem, and a needle coupled to the syringe body. The syringe can be configured such that the plunger is moved through the second lumen along a first direction and the fluid is received into the first lumen along a second direction that is opposite the first direction. | 05-12-2016 |
20160129204 | METHODS AND APPARATUS FOR LANCET ACTUATION - A lancet driver is provided wherein the driver exerts a driving force on a lancet during a lancing cycle and is used on a tissue site. The driver comprises of a drive force generator for advancing the lancet along a path into the tissue site, and a manual switch for a user interface input. | 05-12-2016 |
20160136355 | MEDICAL INFUSION PUMP MECHANISM - A medical device pump with a housing with a compartment for removably receiving a cartridge containing a therapeutic agent, a conduit configured to operatively provide a fluid flow path for therapeutic agent to exit from the cartridge, a user activated delivery button, a trigger mechanism, and a pump mechanism employing an articulating, coiled drive spring. | 05-19-2016 |
20160136363 | REPEATABLE INJECTION TARGETING SYSTEM - Systems and method of targeted injection are provided. A method includes: capturing an image of a subject; displaying the image on a touch screen display; providing input to the touch screen display, wherein the input generates at least one mark superimposed on the image; saving the image and the at least one mark as a modified image; projecting the modified image onto the subject; and administering an injection to the subject where the at least one mark is projected on the subject. | 05-19-2016 |
20160136406 | HOLLOW MICRONEEDLE WITH BEVELED TIP - An article having at least one microneedle ( | 05-19-2016 |
20160136407 | MICRONEEDLE ARRAYS FOR CANCER THERAPY APPLICATIONS - A method of forming a microneedle array can include forming a microneedle array having one or more chemotherapeutic agents. The microneedle array can include a base portion and plurality of microneedles extending from the base portion, and the one or more chemotherapeutic agents can be present in a higher concentration in the plurality of microneedles than in the base portion. | 05-19-2016 |
20160136410 | INTRAOSSEOUS INFUSION PORTS AND METHODS OF USE - Example embodiments are related to intraosseous infusion port (IOP) devices to provide access to bone marrow cavities. The IOP device according to example embodiments may comprise a proximal portion with a hollow chamber extending through the proximal portion, the hollow chamber having a proximal inlet for receiving an insertion device. The IOP device may also include an anchor portion positioned distally to the proximal portion, the anchor portion may be configured for anchoring the infusion port device in a bone, and an open-ended channel extending through the anchor portion, the channel being in fluid communication with the hollow chamber, such that, when the infusion port is implanted into a bone, the channel and the hollow chamber create a substantially straight pathway terminating at an opening at its distal end for insertion of the insertion device towards the bone marrow. | 05-19-2016 |
20160144100 | MICRO-NEEDLE DRUG DELIVERY SYSTEMS - Generally, devices, systems and methods of using one or more needle(s) or micro-needle arrays are described in which a shift of fluid volume from a first expansion member position to a second expansion member position drives delivery of the fluid, which can be a drug or drug solution, through the needle(s) or micro-needle arrays. | 05-26-2016 |
20160144101 | MECHANICAL INJECTION PUMP AND METHOD OF USE - A mechanical injection pump wearable by a user to deliver a first fluid and a second fluid, including: a pump body having a first fluid chamber to hold the first fluid and a second fluid chamber to hold the second fluid; a common connector having a first inlet, a second inlet, and a common outlet; a first fluid system including the first fluid chamber, a first button drive connected to the first fluid chamber, and first fluid delivery path between the first fluid chamber and the first inlet; and a second fluid system including the second fluid chamber, a second button drive connected to the second fluid chamber, and second fluid delivery path between the second fluid chamber and the second inlet. Force by the user on the button drive increases pressure within the fluid chamber to drive a predetermined volume of the fluid from the fluid chamber. | 05-26-2016 |
20160144119 | Syringe with Visually Coded Needle Hub - A medication delivery device included molded cylindrical barrel having visual marks on the surface of the barrel in the axial direction, a plunger seals the distal opening of the cylindrical barrel, a molded needle hub disposed in the proximal opening of the cylindrical barrel for sealing the needle hub to the barrel. A needle is disposed in the needle hub for communicating liquids by operation of the plunger in the axial direction. The circumferential surface on the flange of the needle hub comprises a colored mark that corresponds to a characteristic of the medication delivery device or its contents. | 05-26-2016 |
20160144122 | Syringe Assembly with Plunger Rod Backstop and Method of Use - A syringe assembly includes a syringe barrel having a tubular body that bounds a compartment extending between a proximal end and an opposing distal end and a flange that radially outwardly projects from the proximal end of the body. A stopper is movably disposed with the compartment of the syringe barrel. A plunger rod includes a shaft having a proximal end and an opposing distal end and a plurality of teeth disposed on the shaft, the distal end of the shaft being secured to the stopper. A backstop engages the flange of the syringe barrel and at least a portion of the plurality of teeth of the plunger rod. | 05-26-2016 |
20160144125 | SYRINGE EXTRUSION ACCESSORY - Described herein are syringe extrusion accessories comprising: a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one pawl operatively coupled to the handle and configured to engage with a plunger of the syringe, wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe. | 05-26-2016 |
20160144136 | PORTABLE FLUID WARMER - A method for warming infusion or transfusion fluids by an exothermic reaction of a reactive liquid using a warming device. The device comprises a reaction chamber and a secondary chamber. The reaction chamber and the secondary chamber are aligned end on and are abutting. The reaction chamber contains a trigger and the secondary chamber contains the reactive liquid. The exothermic reaction results when the reactive liquid contacts the trigger leading to crystallization of the reactive liquid. The secondary chamber is compressible. An inlet is positioned between the secondary chamber and the reaction chamber to allow passage of the reactive liquid. The inlet is transversely elongate relative to the flow of the reactive liquid. A frangible or removable barrier closes the inlet. A passageway for movement of said infusion or transfusion fluids extends through reaction chamber. The passageway, the reaction chamber and the secondary chamber are all flexible. The method comprises the steps of rupturing or removing the barrier; urging reactive liquid from the secondary chamber into the reaction chamber by compressing the secondary chamber and rolling up the secondary chamber, the reaction chamber expanding on receiving the reactive liquid; continuing to roll the device so that the reaction chamber is rolled around the secondary chamber two or more times before the reactive liquid solidifies, and passing infusion or transfusion fluid through the passageway after the exothermic reaction has commenced. | 05-26-2016 |
20160144137 | RETRACTABLE INSULIN INFUSION SYSTEM - A device for introducing a liquid (e.g., insulin) into tissue of a subject (e.g., a mammal, such as a human) in need of the liquid. The device includes a cannula having a distal tip. A cannula positioner adjustably (and incrementally) controls a position of the cannula after introduction subcutaneously into a subject. A cannula positioner body allows adjustable support of the cannula and the cannula positioner and may be worn by the subject. The cannula positioner includes a cannula position control member that is adapted to be driven (e.g., longitudinally) to advance or retract the cannula so that a subcutaneous position of the distal tip is changeable among a plurality of locations over a period of at least four days, without removal of the cannula from the subject. | 05-26-2016 |
20160144161 | DRUG RELEASING PELVIC TREATMENT SYSTEM AND METHOD - Various embodiments of a pelvic treatment system and method are provided. The present invention can include one or more drug eluting darts or barbs that are lodged into the wall and will elute the drug over a desired time period (weeks, months for example) to treat OAB, BPH, tissue weaknesses, or other disorders or diseases. | 05-26-2016 |
20160151015 | SYSTEM AND METHOD FOR DYNAMICALLY ADJUSTING PATIENT THERAPY | 06-02-2016 |
20160151565 | FLUID CONTAINER DISPLACEMENT PUMP | 06-02-2016 |
20160151575 | INTRATHECAL BACLOFEN PHARMACEUTICAL DOSAGE FORMS AND RELATED DELIVERY SYSTEM | 06-02-2016 |
20160151608 | Self-Anchoring Catheters and Methods of Use | 06-02-2016 |
20160158101 | SYRINGE FOR AND METHOD OF DELIVERING A VOLUME OF SOLUTION - Methods and apparatuses are disclosed with regard to syringe-transfer of a solution or other fluid within a carpule. One embodiment includes an apparatus that is a non-standard carpule barrel having a top portion, a bottom portion, and a barrel portion therebetween. The top portion includes an opening for receiving a syringe plunger and at least a first portion of a connection mechanism for connecting to an upper portion of the syringe. The bottom portion includes another opening capable of holding a bottom end of the carpule, wherein the carpule may be a standard carpule or a non-standard carpule. The barrel portion is located between the top portion and bottom portion, wherein the barrel portion includes a cradle, and wherein the cradle has a length capable of holding a standard carpule or a non-standard carpule and a width greater than the standard carpule. | 06-09-2016 |
20160158429 | HYPERTHERMIC BODY FLUID TREATMENT SYSTEM AND METHOD FOR THE SAME - A method for hyperthermic treatment of body fluid includes diverting at least a portion of a body fluid through a body fluid inlet from a body. A viral load of a pathogen is measured in the body fluid, and a target treatment temperature is determined based on the measured viral load. The body fluid is heated to the target treatment temperature to decrease the viral load in the body fluid. The body fluid is returned to the body after hyperthermic treating through a body fluid outlet. Hyperthermic treating of the body fluid is repeated with another portion of body fluid diverted through the hyperthermic treatment assembly. | 06-09-2016 |
20160158447 | SYRINGE FOR AND METHOD OF DELIVERING A VOLUME OF SOLUTION WITH GUIDANCE BEARING IN VIEW OF STANDARD AND NON-STANDARD CARPULES - Methods and apparatuses are disclosed with regard to syringe-transfer of a solution or other fluid, optionally with a guidance bearing, within a standard or non-standard carpule, optionally having sealed top ends and measurement gradations, i.e., indicia. One embodiment is a non-standard carpule barrel having a top portion, a bottom portion, and a barrel portion therebetween. The top portion includes an opening for receiving a syringe plunger and at least a first portion for connecting to an upper portion of the syringe. The bottom portion includes another opening capable of holding a bottom end of the carpule, wherein the carpule may be a standard carpule or a non-standard carpule. The barrel portion is located between the top portion and bottom portion, and includes a cradle, which has a length capable of holding a standard or a non-standard carpule, which has a greater width than a standard carpule. | 06-09-2016 |
20160158450 | AUTOMATIC INJECTION DEVICES HAVING OVERMOLDED GRIPPING SURFACES - Exemplary embodiments provide automatic injection devices, housing components for automatic injection devices and methods for fabricating the same. An exemplary housing of an automatic injection device may be overmolded with one or more gripping surfaces to facilitate gripping and manipulation of the automatic injection device by a user when performing an injection. In an exemplary embodiment, an overmolded left gripping surface may extend along a left side of the housing and an overmolded right gripping surface may extend along a right side of the housing opposite to the left side. | 06-09-2016 |
20160158516 | THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE - Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. | 06-09-2016 |
20160166429 | Methods and Devices for Pain Management | 06-16-2016 |
20160166650 | THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE | 06-16-2016 |
20160166761 | Apparatus, Kits and Related Methods for Fluid Infusion | 06-16-2016 |
20160166764 | Patch-Sized Fluid Delivery Systems and Methods | 06-16-2016 |
20160166767 | Fluid Line Occlusion Detection System And Methods | 06-16-2016 |
20160166774 | SAFETY SYRINGE AND METHODS FOR ADMINISTRATION OF A MEDICAMENT DOSE BY SUBJECT WEIGHT | 06-16-2016 |
20160166777 | DEVICE, SYSTEM AND METHOD FOR DELIVERY OF A LONG-ACTING DRUG | 06-16-2016 |
20160166819 | HOLLOW MICRONEEDLE WITH BEVEL OPENING | 06-16-2016 |
20160175408 | DIRECT APPLICATION SYSTEM AND METHOD FOR THE DELIVERY OF BIOACTIVE COMPOSITIONS AND FORMULATIONS | 06-23-2016 |
20160175524 | AUTO-INJECTOR | 06-23-2016 |
20160175535 | METHODS OF PERFORMING RETROBULBAR INJECTIONS | 06-23-2016 |
20160175536 | PLUNGER RETRACTION FOR LEAK PREVENTION IN INJECTION DEVICE | 06-23-2016 |
20160184531 | INJECTION AID FOR USE WITH AN INJECTION DEVICE AND METHOD OF USE - An injection aid for use with an injection device, such as a safety syringe, for example, is disclosed. The injection aid employs a flexible clip-based design to compensate for manufacturing tolerances associated with the injection device. The injection aid includes a body and a lever mounted to the body, the lever being configured to rotate about the body. The injection aid may further include gears rotate with rotation of the lever, and which function to remove a needle shield from the injection device. The body positions the injection device so as to ensure consistent injection depth. | 06-30-2016 |
20160193080 | DEVICE FOR OCULAR ACCESS | 07-07-2016 |
20160193383 | CROSS-LINKABLE TISSUE BULKING COMPOSITIONS | 07-07-2016 |
20160193407 | CONFORMABLE PATCH PUMP | 07-07-2016 |
20160193428 | INJECTION DEVICE | 07-07-2016 |
20160199574 | DRUG DELIVERY DEVICE | 07-14-2016 |
20160199581 | Needle Insertion Device | 07-14-2016 |
20160199592 | DRUG DELIVERY DEVICE COMPRISING A CAP SENSOR AND A RADIATION SENSOR | 07-14-2016 |
20160250403 | METHOD AND DEVICE FOR CREATING TURBULENCE BY PULSATING FLOW | 09-01-2016 |
20160250451 | METHODS OF USING A DUAL-LUMEN SHEATH IN INTRALUMINAL PROCEDURES | 09-01-2016 |
20160375199 | BOOT REMOVER - The invention relates to a boot remover ( | 12-29-2016 |
20160375200 | METHODS FOR UNCAPPING AND RECAPPING A SYRINGE USING A PROTECTION DEVICE - Methods for removing a covering cap from a syringe needle and for recapping the needle, using a protection device with improved functionality, particularly for syringes, comprising a supporting body which is provided with a through hole for the insertion of the covering cap of a needle of a syringe, the supporting body being provided with at least one flat face, being arranged on the opposite side with respect to a face for the insertion of the covering cap in the hole, for the resting contact of the supporting body on a resting surface, the face lying opposite the flat face being provided with a raised perimetric containment rim, the hole having a diameter that is substantially larger than the diameter of the central portion of the covering cap and substantially smaller than the diameter of the end portion of the covering cap, a collar being provided around the hole, the collar extending from the face for the insertion of the covering cap. | 12-29-2016 |
20170231816 | OPHTHALMIC INJECTION DEVICE AND METHOD | 08-17-2017 |
20170232197 | Portable Drug Mixing and Delivery Device and Associated Methods | 08-17-2017 |
20170232229 | INTRABODY SURGICAL FLUID TRANSFER ASSEMBLIES WITH ADJUSTABLE EXPOSED CANNULA TO NEEDLE TIP LENGTH, RELATED SYSTEMS AND METHODS | 08-17-2017 |
20180021526 | PEN NEEDLE HUB WITH A PATIENT CONTACT SURFACE | 01-25-2018 |
20180021548 | LOW PROFILE INTRODUCER APPARATUS | 01-25-2018 |
20190143032 | SUBCUTANEOUS INFUSION SET WITH SIDE PORT FLUID CONNECTOR | 05-16-2019 |
20190143042 | EPINEPHRINE AUTO-INJECTING WATCH AND METHOD OF USE | 05-16-2019 |
20190143083 | AUTOLOGOUS PLEURODESIS METHODS AND DEVICES | 05-16-2019 |
20190143090 | MICRONEEDLE ARRAY ASSEMBLY, DRUG DELIVERY DEVICE AND METHOD FOR ADMINISTERING LIQUID ACROSS A BROAD AREA AT LOW PRESSURE | 05-16-2019 |
20190143092 | TRANSDERMAL DELIVERY OF HIGH VISCOSITY BIOACTIVE AGENTS | 05-16-2019 |
20190147998 | INFUSION PUMP AUTOMATION SYSTEM AND METHOD | 05-16-2019 |
20220133861 | HYALURONIDASE COMPOSITIONS AND METHODS OF USING SAME TO TREAT EDEMA - The present disclosure provides a method of treating edema in a subject in need thereof, comprising the step of administering a composition that comprises a protein having hyaluronidase activity to a region of the subject having edema. | 05-05-2022 |
20220134072 | MINIATURIZED DELIVERY SYSTEM AND METHOD - A miniature delivery system includes a base; a pumping mechanism attached to the base; and a housing having needles, the housing being attached to the base so that the pumping mechanism is enclosed by the housing. The needles are configured to not buckle or break when pressed directly into a skin or organ of a human to which the miniature delivery system is attached to, and the pumping mechanism is configured to pump a fluid from the housing into the skin or organ, through the needles. | 05-05-2022 |