| Entries |
| Document | Title | Date |
|---|
| 20080199945 | CANTILEVER FOR MEASURING INTRA-CELLULAR AND INTER-CELLULAR MICROSPACES - A cantilever for measuring intra-cellular and inter-cellular microspaces of the present invention includes a support portion, a lever portion provided to the support portion so as to protrude therefrom, and a probe portion provided near a free end of the lever portion. The probe portion includes a conductive probe made of a carbon-based material, and an insulating film to coat a periphery of the conductive probe. | 08-21-2008 |
| 20080206847 | PROBE CONNECTOR ASSEMBLY AND METHOD OF USE - A probe assembly includes a tubular sleeve having a passage extending between a first end and an opposing second end. The tubular sleeve is movable between an extended position wherein the first end and the opposing second end are spaced apart and a collapsed position wherein the first end and the opposing second end are moved closer together. A connector is secured to the second end of the tubular sleeve, the connector having an opening extending therethrough that communicates with the passage of the tubular sleeve, a sealing layer removably covering the opening of the connector. An elongated probe has a first end and an opposing second end, the second end of the probe being positioned within the passage of the tubular sleeve, the second end of the probe being configured to pass through the opening of the connector when the sealing layer is removed therefrom. | 08-28-2008 |
| 20080213874 | WEIGHT MEASUREMENTS OF LIQUIDS IN FLEXIBLE CONTAINERS - Articles and methods for measuring weight of a liquid in a disposable bag bioreactor are presented. In certain embodiments, bioreactor systems described herein include a supported container (e.g., a flexible bag in a reusable housing) for containing a liquid, and at least two pressure indicating sensors operatively associated with the container. A first pressure indicating sensor can be placed near the bottom of the container to measure the total downward force within the container, including the liquid head in the container and the gas pressure above the liquid. The second pressure indicating sensor can be placed near the top of the container to measure only the pressure at the top of or above the liquid. Signals from the pressure indicating sensors can be directed to a control system that receives the signals and calculates a difference between the signals. This difference can be used to determine a volume or a weight of the liquid in the container. Advantageously, real-time weight measurements can be obtained while the system is in operation and continuous flow processes can be monitored. Moreover, in some embodiments, the pressure indicating sensors are isolated from contact with any fluid (e.g., liquid) in the container and, therefore, do not require cleaning after processing of each batch of reactants. Contamination of the process fluid by contact with the pressure indicating sensors can also be avoided. | 09-04-2008 |
| 20080220508 | BACTERIOPHAGES THAT INFECT BACILLUS BACTERIA (ANTHRAX) - The invention provides bacteriophages that infect | 09-11-2008 |
| 20080227183 | APPARATUS FOR SUPPORTING DIAGNOSIS OF CANCER - A cancer diagnosis supporting apparatus is provided with a memory for storing a predetermined reference value, a diagnosis support information preparer for preparing the diagnosis support information of cancer by comparing a measurement value obtained from a malignant tumor collected from a cancer patient and the reference value, and a change acceptor for accepting change of the reference value and for storing the changed reference value in the memory. | 09-18-2008 |
| 20080227184 | METHOD, APPARATUS AND SYSTEM FOR QUANTIFYING THE CONTENT OF GENETICALLY MODIFIED MATERIAL IN A SAMPLE - A method including providing an initial test sample including a primary material and a relatively smaller amount of at least one adventitious material; combining the initial test sample with a standard addition of at least one adventitious material to form a final test sample, wherein the standard addition has a known amount of genetically modified adventitious material; and analyzing the final test sample to determine the % GMO of the primary material and the % GMO of the adventitious material. | 09-18-2008 |
| 20080241909 | Microfluidic chips for pathogen detection - The present disclosure relates to methods, systems, devices, and microfluidic chips that may be used for the detection of pathogens. | 10-02-2008 |
| 20080241910 | Devices for pathogen detection - The present disclosure relates to methods, systems, devices, and microfluidic chips that may be used for the detection of pathogens. | 10-02-2008 |
| 20080241911 | Analyzer - A sample analyzer for analyzing a biological sample is disclosed that comprising: a measurement specimen preparation section for preparing a measurement specimen by using a reagent and the biological sample; a irradiator for irradiating the measurement specimen with a light; a first light receiving section for receiving a light from the measurement specimen and converting the received light into an electrical signal; a analysis section for analyzing the measurement specimen based on the electrical signal output by the first light receiving section; and a selection section for selecting an intensity of light to be irradiated by the irradiator, wherein the irradiator is configured to irradiate with a light of an intensity corresponding to the light intensity selected by the selection section. | 10-02-2008 |
| 20080274539 | Bioreactor for Studying the Effects of Imposed Stimuli on Cellular Activity - A bioreactor device for studying the effects of physical, chemical, mechanical and electromagnetic stimuli on the cellular activity. In particular, the device uses a sensorized premixing chamber ( | 11-06-2008 |
| 20080280351 | METHOD AND APPARATUS FOR PREPARING CELLS FOR MICROTOME SECTIONING AND ARCHIVING NUCLEIC ACIDS AND PROTEINS - A method and apparatus for embedding cells that utilizes a flow-through embedding technique maximizes the efficiency of extractions and decreases time for embedding the cell fragments, minimizes cell loss, and automatically positions cell samples at the position in which a microtome blade will section them. The apparatus includes a cell flow pathway defined by an inflow tube for delivering cell fragments from a cell sample to a sample port. The sample port is in fluid communication with a tissue cassette having attached thereto a filter. The cell flow pathway is in communication with a reagent flow pathway for delivering the reagents through the sample port to the cassette. The apparatus is configured such that the application of pressure directs the cell fragments from the cell sample through the cell flow pathway, and effects delivery of the reagents through the reagent flow pathway. The apparatus produces an embedded cell block having concentrated cells near the plane of the block to be sectioned in a quick and efficient manner. | 11-13-2008 |
| 20080280352 | Method and equipment for cultivating anaerobic ammonium-oxidizing bacteria - The present invention can feed substrates without waste to generate seed sludge with high bacterial cell concentrations and can start up operation within a short time, in cultivating anaerobic ammonium oxidizing bacteria with ammonium and nitrite as substrates. Equipment for cultivating anaerobic ammonium-oxidizing bacteria, which cultivates, in a cultivation tank, novel anaerobic ammonium-oxidizing bacteria that anaerobically denitrify nitrite and ammonium used as substrates, comprises an ammonium feed device which feeds ammonium at a given concentration into the cultivation tank, a nitrite feed device which feeds nitrite at a given concentration into the cultivation tank, and a control device which controls a feed rate Y of the substrate. | 11-13-2008 |
| 20080311648 | Biosensor for analyzing quantitatively analyte with a predetermined size and larger than, and manufacturing method thereof - The present invention discloses a biosensor for quantitatively analyzing a bio-material and a manufacturing method thereof. The biosensor has an exposed conductive region of a few-nanometer scale distributed on an insulated metallic substrate in a desired pattern or randomly. The quantitative analysis of protein can be carried out by means of simplified procedures, without the necessity of rinsing out a signal-producing material, which is non-specifically bonded to the materials to be analyzed. The biosensor utilizes only the size of the molecules, and thus can be universally used for the analysis of bio-materials. A selective and separate analysis can be realized in which interference caused by other materials is significantly reduced. | 12-18-2008 |
| 20090023200 | PARTICLE FOR DETECTING ENZYME ACTIVITY, METHOD FOR DETECTING THE ENZYME ACTIVITY AND ENZYME ACTIVITY DETECTION DEVICE BY THE USE THEREOF - An object is to provide a particle for detecting an enzyme activity wherein by measuring an intensity of a fluorescence wavelength in a sample solution, it is possible to not only detect the presence or absence of an enzyme but also accurately perform a quantitative analysis of the enzyme in the sample solution, handleability is excellent as well as measurement accuracy and quantitative property can be enhanced because the present invention is hardly influenced by absorbed moisture and weighing errors hardly occur, and further productivity is remarkably excellent because complicated steps such as a step of cleaving and purifying a synthesized peptide and a step of lyophilizing are not required upon production thereof. | 01-22-2009 |
| 20090035845 | Method and device for extracting and/or collecting blood from placenta and/or umbilical cord - A device for extracting and collecting blood from a delivered placenta comprising a compartment to contain and support a delivered placenta and umbilical cord. The compartment includes a flexible membrane which can be displaced (preferably under the influence of a fluid (preferably gas) pressure differential between the compartment side and non compartment side of the membrane) to impart onto the placenta a pressure to encourage the displacement of fluid carried by the placenta towards the umbilical cord. The compartment includes at least one outlet opening via which the umbilical cord can extend (preferably in a sealed manner) to allow the flexible membrane pressure induced flow of fluid carried by the placenta to displace from the compartment for external to the compartment collection of the fluid. | 02-05-2009 |
| 20090047731 | CELLULAR ELECTROPHYSIOLOGICAL MEASUREMENT DEVICE AND METHOD FOR MANUFACTURING THE SAME - A cellular electrophysiological measurement device includes a thin plate and a frame. The thin plate has a first surface with a depression and a second surface with a through-hole. The frame is in contact with an outer periphery on the second surface of thin plate. The thin plate has a laminated structure of at least two layers including a first material layer on the first surface and a second material layer on the second surface. The frame is formed of a third material layer. The structure allows the cellular electrophysiological measurement device to be not so vulnerable to breakage of thin plate and other damages, thereby having high production yield. | 02-19-2009 |
| 20090081765 | CELL ELECTROPHYSIOLOGICAL SENSOR AND METHOD FOR MANUFACTURING THE SAME - In a cell electrophysiological sensor having a thin plate with a through hole, a support plate with a through hole and a container plate with a through hole stuck to an upper portion of this support plate, the support plate and the container plate are stuck to each other through fusion with a portion of the outer shape of a first electrode in a ring shape intervening in a portion of the interface. In this configuration, a cell electrophysiological sensor which allows for measurement with high precision can be attained, and a manufacturing method which is excellent in terms of mass production can be provided. | 03-26-2009 |
| 20090081766 | MICRO BIO SENSOR AND METHOD FOR MANUFACTURING THE MICRO BIO SENSOR - A micro bio sensor which detects a microbe existing in a specimen is provided. The microbial sensor includes a base, a detector formed on the base, and a reaction layer formed on the detector, wherein the reaction layer is comprised of a self-assembled monolayer which is formed on the detector and an antibiotic which is immobilized through the self-assembled monolayer on the detector. By using the micro bio sensor, it is possible to detect species of the microbe concurrently and improve sensitivity for detecting the species of the microbe. Further, a method for manufacturing such a micro bio sensor is also provided. | 03-26-2009 |
| 20090093045 | ORGANISM TESTING APPARATUS - An organism testing apparatus adapted to measure the organisms in a specimen in stable fashion is disclosed in which the organisms are stained, the specimen is concentrated and the information on the organisms contained in the specimen are acquired through a simple process. The apparatus includes a staining unit for staining the organisms having live cells existing in a flowing liquid specimen, a concentration unit for concentrating the organisms in a flowing stained specimen, an individual measuring unit for acquiring the image information on the individuals containing the organisms in the concentrated specimen, and a control unit for measuring the organisms based on the image information on the individuals output from the individual measuring unit. | 04-09-2009 |
| 20090098643 | MULTILAYER CIRCUIT DEVICES AND MANUFACTURING METHODS USING ELECTROPLATED SACRIFICIAL STRUCTURES - A multilayer circuit includes a dielectric base substrate, conductors formed on the base substrate and a vacuum deposited dielectric thin film formed over the conductors and the base substrate. The vacuum deposited dielectric thin film is patterned using sacrificial structures formed by electroplating techniques. Substrates formed in this manner enable significant increases in circuit pattern miniaturization, circuit pattern reliability, interconnect density and significant reduction of over-all substrate thickness. | 04-16-2009 |
| 20090104689 | Microchip For Use In Cytometry, Velocimetry And Cell Sorting Using Polyelectrolytic Salt Bridges - The present invention relates to a microchip using polyelectrolyte salt bridge for cytometry, velocimetry, and cell sorting. The microchip comprises; a) an inlet for solution to be analyzed, b) a microchannel which provides a moving passage for solution to be analyzed, c) at least one outlet for solution to be analyzed which has passed through the moving passage, d) at least one electrode system comprising a first and a second salt bridges connected to the microchannel (the two salt bridges face each other), and a first and a second reservoirs connected to said each salt bridge (the reservoir comprises electrode and standard electrolyte solution). The microchip detects analytes in the solution to be analyzed (for example, a cell) by detecting change of impedance. In detail, anion in the standard electrolyte solution, which is comprised in the first reservoir, moves from the first salt bridge to the second salt bridge across the microchannel. Impedance change occurs by interference of anion moving across the microchannel and the change can be detected by impedance analyzer connected to electrodes in the first and the second reservoirs. | 04-23-2009 |
| 20090104690 | DEVICE FOR DETECTING AN ENZYME IN A SAMPLE - A device for detecting a mammalian host-derived enzyme in a sample of a wound fluid, said device comprising: a housing having an inlet for the sample and side walls defining a fluid flow path extending from said inlet an indicator moiety that is bound to a solid substrate by means of a peptide linker moiety that is cleavable by said host-derived enzyme, said solid substrate being located in a reaction zone of said fluid flow path; and a detector moiety located in a detection zone downstream from the reaction zone in said fluid flow path, wherein the detector moiety interacts with an indicator moiety that has been cleaved from said solid substrate to produce a detectable change in said detection zone. Suitably, the device further comprises a control moiety located in a control zone in said device, wherein the control moiety can interact with a component of the wound fluid sample to improve the accuracy of the device. Also provided are systems comprising a device of the invention and a swab or biopsy punch adapted for use therewith. | 04-23-2009 |
| 20090111168 | BIOCHIP AND METHOD OF FABRICATION - A biochip and method of fabricating the same are provided. The biochip can include a substrate, a capping layer pattern partially covering a top surface of the substrate, and a plurality of probes coupled to the top surface of the substrate exposed by the capping layer pattern. | 04-30-2009 |
| 20090111169 | BIOCHIP AND METHOD OF FABRICATION - A biochip and method of fabricating the same are provided. The biochip can include a substrate, a plurality of active pads formed on the substrate, each of the plurality of active pads having a surface roughness and being patterned so as to produce photonic crystals, and a plurality of probes directly or indirectly coupled with at least some of the plurality of active pads. | 04-30-2009 |
| 20090142825 | COMPOSITE DETECTION DEVICES HAVING IN-LINE DESALTING AND METHODS OF MAKING THE SAME - A composite detection device having in-line desalting is provided. The composite detection device comprises a membrane configured for desalting at least a portion of an analyte stream, and a nanostructure for detecting a bio-molecule or a bio-molecule interaction, wherein the nanostructure and the membrane are arranged such that an analyte stream desalted at least in part by the membrane is detected by the nanostructure. A bio-sending detection system having the composite detection device and method of fabrication of the composite detection device are also provided. | 06-04-2009 |
| 20090142826 | Diffraction-Based Diagnostic Devices - A biosensor includes a substrate with areas of active receptive material disposed thereon. The receptive material is specific for an analyte of interest. A pattern of the active areas is defined on the substrate by an oxidizing photo-masking process. | 06-04-2009 |
| 20090162927 | NANOTUBES AND NANOWIRES BASED ELECTRONIC DEVICES AND METHOD OF FABRICATION THEREOF - An electronic device is presented comprising at least one electrically conductive element coupled to an elongated carbon or inorganic semiconductor based nanostructure, by a biological binder. | 06-25-2009 |
| 20090181450 | Metod and unit for preparing a sample for the microbiological analysis of a liquid - The preparation unit comprises a body ( | 07-16-2009 |
| 20090186401 | LID FOR PCR VESSEL COMPRISING PROBES PERMITTING PCR AMPLIFICATION AND DETECTION OF THE PCR PRODUCT BY HYBRIDISATION WITHOUT OPENING THE PCR VESSEL - The present invention proposes a simple and effective lid being part of a device having multiwells for performing simultaneous amplifications by PCR and detections of multiple target molecules on unlabeled capture molecules immobilized on the lid. | 07-23-2009 |
| 20090191615 | DEVICE FOR DETERMINING THE QUALITY AND SOLIDNESS OF THE VASCULAR WALL - A device for determining the quality and solidness of the vascular wall is provided for testing tissue samples and includes opposed first and second fixation plates. The fixation plates are connectable to an air pump or other source of vacuum for fixing the tissue sample in position. The device is connectable to a detector such as a meter, gauge, or printing device capable of displaying or producing an image or display corresponding to the value of a force required to disrupt or break the internal links between individual layers of the vascular wall. The fixation plates are movable relative to one another and may be abducted by abductors connecting the plates or by rotational movement of one fixation plate relative to the other by a shaft or other rotational mechanism. | 07-30-2009 |
| 20090215156 | Method for Fabricating Nanogap and Nanogap Sensor - The present invention relates to a method of fabricating a nanogap and a nanogap sensor, and to a nanogap and a nanogap sensor fabricated using the method. The present invention relates to a method of fabricating a nanogap and a nanogap sensor, which can be realized by an anisotropic etching using a semiconductor manufacturing process. According to the method of present invention, the nanogap and nanogap sensor can be simply and cheaply produced in large quantities. | 08-27-2009 |
| 20090221058 | Potentiometric biosensor for detection of lactate in food and forming method thereof - The present invention discloses a potentiometric biosensor for detecting lactate in food, and the forming method thereof. The disclosed biosensor comprises a substrate, and conducting layer on the substrate, an oxide layer on the conducting layer, and an enzyme layer on the oxide layer, wherein the enzyme layer comprises Lactate dehydrogenase (LDH). The detection signal is transmitted for further processing through a wire connected to the conducting layer, or a window formed on the surface of conducting layer. | 09-03-2009 |
| 20090246860 | POINT SOURCE DIFFUSION CELL ACTIVITY ASSAY APPARATUS - Apparatuses and methods for determining whether a test compound solution induces cell activity, an embodiment of the method of the present invention comprising placing a test compound solution in contact with a cell suspension media containing cells, diffusing the test compound solution into the cell suspension from a point source, and detecting activity in the cells with respect to their distance from the point source. Detecting activity in the cells can involve detecting activity in a first group of the cells proximate to the point source, and detecting activity in a second group of the cells farther from the point source than the first group. | 10-01-2009 |
| 20090253193 | Apparatus and Method for Evaluating Ex Vivo Tissue Samples by Electrical Impedance - A device for characterizing ex vivo tissue employs a set of independent electrodes that may be used to scan the tissue by moving a voltage gradient across the tissue surface acquiring impedance spectrographs that may be mapped to an image. | 10-08-2009 |
| 20090269837 | System for assessing the efficacy of stored red blood cells using microvascular networks - A system for assessing the microvascular fitness of a sample of stored red blood cells. The system has a network device having at least one network unit. The network unit has a single inlet and a single outlet for the sample and a plurality of microchannels. The plurality of microchannels receive the sample from the single inlet and drain the sample into the single outlet. The network unit includes an aspiration pressure means for providing movement of liquid sample through the at least one network unit. The system further includes an analysis unit that receives the network device therein. The analysis unit includes a sensor for capturing measurements related to the sample and a processor capable of comparing the captured measurements to measurements stored in a database of healthy red blood cells to determine the microvascular fitness of the stored red blood cells. | 10-29-2009 |
| 20090275115 | MICROREACTOR - Chemical and biological reactors, including microreactors, are provided. Exemplary reactors include a plurality of reactors operable in parallel, where each reactor has a small volume and, together, the reactors produce a large volume of product. Reaction systems can include mixing chambers, heating/dispersion units, reaction chambers, and separation units. Components of the reactors can be readily formed from a variety of materials. For example, they can be etched from silicon. Components are connectable to and separable from each other to form a variety of types of reactors, and the reactors can be attachable to and separable from each other to add significant flexibility in parallel and/or series reactor operation. | 11-05-2009 |
| 20090286308 | Process for assembling two surfaces or one surface with a molecule of interest - The present invention relates to a process for assembling at least one zone of a first surface with at least one zone of a second surface or with a molecule of interest, comprising a step that consists in placing the said zone of the said first surface in contact with the said zone of the said second surface or with the said molecule of interest, the said zone of the said first surface bearing at least one radical and/or ionic species. The present invention also relates to a solid support whose surface bears at least one zone with at least one radical and/or ionic species, with at least one adhesion primer, or with at least one adhesion primer precursor, and to its various uses. | 11-19-2009 |
| 20090305393 | Apparatus, System, and Method for in-Situ Measurements - The present invention relates to apparatus, systems and methods for performing in situ measurements, and, more particularly, to apparatus, systems and methods that can isolate a sample from a bulk fluid to measure characteristics of same without unwanted effects of perturbation in the bulk fluid. | 12-10-2009 |
| 20090311773 | Novel apparatus and method for coating substrates for analyte detection by means of an affinity assay method - The invention relates to several embodiments of equipment for coating substrates for detecting one or more analytes by way of an affinity assay method, comprising: a receptacle receiving a liquid to be atomized (“liquid receptacle”) with substances (compounds) to be deposited onto at least one surface of said substrates and an atomized volume produced by the liquid in the operating state; an actuator for triggering the atomization process and; a fixture for receiving and storing the substrates during the coating process. The invention is characterized in that the substrates are not in contact with the surface of the liquid to be atomized. The invention also relates to several embodiments of methods for coating substrates with coupler and/or passivation layers for use in the detection of one or more analytes by way of an affinity assay method. | 12-17-2009 |
| 20090317896 | THIN FILM CHEMICAL ANALYSIS APPARATUS AND ANALYSIS METHOD USING THE SAME - Disclosed is a thin film chemical analysis apparatus and an analysis method using the same, which can solve the sealing problem caused by environmental factors (e.g. impact, temperature) for long circulation and storage periods, as well as can detect an analyte quickly and easily. The thin film chemical analysis apparatus includes at least one chamber adapted to store a fluid necessary for biological or biochemical analysis or to conduct a biological or biochemical reaction; channels for fluid-connection of the chambers; holes arranged between or inside the channels and connected to the channels; a rotatable body having the chambers, the channels, and the holes integrated into the body; and a burst valve having a sealing means for closing the hole and sealing a fluid in the chamber, the sealing means being torn away from the hole by centrifugal force resulting from rotation of the body and opening the hole. | 12-24-2009 |
| 20090325275 | CELL MANIPULATION AND CULTIVATION EQUIPMENTS FOR THE PRODUCTION OF CELL THERAPY PRODUCTS - Cell manipulation and cultivation equipment for the production of cell therapy products has developed for preventing contamination of cells and improving the utility of a space. The equipment includes a room for the production and testing of cell therapy products, the room having an inner space enclosed in all sides and an outer entrance/exit door provided at any one side thereof, an L-shaped partition installed in a position of the room for the production and testing of cell therapy products, the partition having an inner entrance/exit door provided at any one side thereof, and a clean bench device placed inside the partition, the clean bench device including first, second, and third clean benches for preventing contamination of cells and increasing the utility of a space to the maximum extent. The operating of the clean room and clean bench has advantages to prevent contamination and improving the quality and reliability of cell therapy products. | 12-31-2009 |
| 20100009430 | Analytical cartridge with fluid flow control - Analytical cartridges, systems and methods of processing a sample for analysis using capillary flows. Vertical gradient sample filtration provides filtrate to an incubation chamber for a time controlled by a flow modulator at the outlet of the incubation chamber. The flow modulator can include a serpentine capillary flow path without side walls. Incubated filtrate can flow from the incubation chamber to a detection channel after a predetermined time. The detection chamber can include one or more analytical regions in a porous substrate for detection of two or more analytes on the same cartridge from the same sample. | 01-14-2010 |
| 20100009431 | CARTRIDGE CONTAINING REAGENT, MICROFLUIDIC DEVICE INCLUDING THE CARTRIDGE, METHOD OF MANUFACTURING THE MICROFLUIDIC DEVICE, AND BIOCHEMICAL ANALYSIS METHOD USING THE MICROFLUIDIC DEVICE - A microfluidic device including a platform and a cartridge is disclosed. The platform includes a chamber containing a fluid. The reagent cartridge is mounted to the platform. and contains a solid reagent for detecting material contained in the fluid. | 01-14-2010 |
| 20100028981 | SPECIMEN COLLECITON AND ASSAY CONTAINER - The present invention includes but is not limited to a specimen collection device that includes a chamber capable of collecting a specimen, a specimen passage slot, a reservoir, a reservoir seal, and a test device. A sample or specimen added to the chamber flows through the specimen passage slot into the reservoir. Flow into the reservoir may be limited by the reservoir seal. The test device positioned within the reservoir detects the presence or concentration of an analyte within the sample or specimen. | 02-04-2010 |
| 20100028982 | DEVICE FOR, AN ARRANGEMENT FOR AND A METHOD OF ANALYSING A SAMPLE | 02-04-2010 |
| 20100035332 | PORTABLE DETECTION APPARATUS FOR BEVERAGE INGREDIENTS - Embodiments of the invention relate to portable detection apparatus, comprising one or more detector regions adapted to visually indicate the presence or amount of an analyte in a beverage. The detection apparatus is shaped substantially the same as a consumer product. | 02-11-2010 |
| 20100035333 | JOINED BODY TO PROVIDE FLUID ANALYSIS AND MANUFACTURING METHOD THEREOF - A joined body to provide fluid analysis having an improved joining structure, and a manufacturing method thereof. The joined body includes a plurality of pieces, and adhesive passages formed inside the joined body and filled with an adhesive resin to form a joint, where the pieces are bonded to each other by the joint. | 02-11-2010 |
| 20100035334 | BIOLOGICAL SAMPLE MEASUREMENT APPARATUS - A wireless blood glucose meter ( | 02-11-2010 |
| 20100035335 | METAL-ENHANCED FLUORESCENCE FOR THE LABEL-FREE DETECTION OF INTERACTING BIOMOLECULES - A method for enhancing fluorescence of a biomolecule includes the step of associating the biomolecule having intrinsic fluorescence with a sensing surface that contains nanostructured metal. Association of the biomolecule with the nanostructured metal enhances its intrinsic fluorescence, which is detected upon exposure to electromagnetic radiation of a suitable wavelength. The sensing surface may include capture or ligand molecule which binds to the biomolecule and sequesters it in proximity to the nanostructured metal, thereby causing its fluorescent signal to be enhanced. The method can be used in label-free bioassays for detection of interacting biomolecules, such as antibody-antigen binding. | 02-11-2010 |
| 20100062520 | Biomaterial Measuring Device and Manufacturing Method Thereof - A method of producing a biomaterial measuring device is disclosed. The method includes forming a plurality of reactions elements, to which an assay reagent is applied, on a first substrate, cutting the resulting first substrate in a unit of individual reaction element, and attaching a first substrate piece, which is formed by cutting the resulting first substrate in the unit of individual reaction element, to a predetermined portion of a second substrate. In the biomaterial measuring device, since a material cost in minimized and it is easy to automate production, it is possible to reduce a production, it is possible to reduce a production cost. | 03-11-2010 |
| 20100068795 | BLOOD TEST DEVICE - It is intended to make it easy to recognize the attachment site of a blood sensor in a blood test device to which the blood sensor is attached by insertion. Especially, it is attempted to make the recognition of the attachment site easy and facilitate the insertion of a blood sensor which is to be attached to a blood test device by a person with visual impairment (in particular, a patient suffering from diabetic retinopathy) for the daily measurement of blood glucose level. More specifically speaking, it is intended to provide a blood test device comprising a housing; an electrical circuit unit contained in the housing; and an attachment site for inserting a blood sensor thereinto that is exposed on the surface of the housing; wherein the surface of the attachment site has a color which is lighter than the surface color of the housing and distinguishable by a patient having impairment in the blue cone. | 03-18-2010 |
| 20100068796 | Blood Glucose Tracking Apparatus and Methods - A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand-held computer. Electronics determine the amount of glucose present in a sample of body fluid, when the test strip is positioned in the receptacle and the body fluid is placed on a test strip, and communicate the glucose amount to the hand-held computer via the connector portion. | 03-18-2010 |
| 20100075406 | CELL CULTURE APPARATUS, CELL CULTURE SYSTEM AND CELL CULTURE METHOD - By maintaining the cell density during culture at an appropriate level and eliminating the procedure of transferring cells from a container to another container when a large amount of cells are cultured, damage on cells can be reduced, risk of contamination can be lowered, labor saving can be attained and automation can be attained. | 03-25-2010 |
| 20100081188 | APPARATUS FOR DETECTING DRUGS IN A BEVERAGE - A test kit for detecting the presence of one or more drugs in a beverage comprising a support having a plurality of detector strips attached thereto. Drugs to be detected are e.g. benzodiazepines, gamma hydroxy butyrate (GHB), Ketamines, Ectasy (MDMA), cocaine barbiturates, opiates, cannabis and flunitrazepam (Rohypnol®). | 04-01-2010 |
| 20100081189 | Sample Chamber - The invention relates to a sample chamber for testing samples, comprising a bottom plate and a cover plate connected thereto, a sample reservoir for receiving a liquid and/or a sample to be tested, and a contact electrode which is arranged entirely in the bottom plate, in the cover plate or between the bottom plate and the cover plate and which is electrically conductively connected to a conductor element or semiconductor element disposed in and/or on the sample chamber, wherein the bottom plate and/or the cover plate are designed in such a way that an electrical contact with the contact electrode can be established from the outside in such a way that an electrically conductive connection to the conductor element or to the semiconductor element can be established from the outside through the bottom plate or through the cover plate via the contact electrode. | 04-01-2010 |
| 20100086992 | BIOSENSOR, BIOSENSOR CHIP AND METHOD FOR PRODUCING THE BIOSENSOR CHIP FOR SENSING A TARGET MOLECULE - A biosensor chip for sensing a target molecule, includes: a substrate having a surface with a sensing area; and adhesive material for immobilizing a mollicute having a cell membrane on the sensing area. The chip may includes cell-resistant material for preventing the mollicute from being immobilized on those parts of the surface of the substrate that do not belong to the sensing area. Further, the adhesive material may comprise a first adhesive material for immobilizing a body of the mollicute on the sensing area and a second adhesive material for immobilizing a tip of the mollicute on the surface of the substrate. | 04-08-2010 |
| 20100093067 | Gassing or Fumigation Device and System - Gassing or fumigation apparatus comprising a one-piece specimen receptacle block including at least two specimen receptacles formed therein and a fluid supply device formed therein for the at least two specimen receptacles, and a gassing or fumigation head for supplying gassing or fumigation medium, which gassing or fumigation head is connected to the specimen receptacle block, comprises a gassing or fumigation medium outlet for each of the at least two specimen receptacles and a device formed therein for conducting gassing medium to the gassing or fumigation medium outlets, and gassing or fumigation system including such a gassing or fumigation apparatus. | 04-15-2010 |
| 20100099173 | QUANTITATIVE LIQUID INJECTION DEVICE OF PLASMA STERILIZER - Disclosed herein is a device for quantitatively supplying a liquid in a plasma sterilization system. The device includes a quantitative cylinder, a quantitative piston and a quantitative basket. The quantitative cylinder includes a quantitative inlet pipe, which is configured such that the outlet of a liquid container is inserted thereinto, and a liquid in the liquid container is vertically supplied to the quantitative cylinder, and a quantitative outlet pipe, which is configured such that the liquid is vertically drained from the quantitative cylinder. The quantitative piston is configured to rectilinearly reciprocate in the quantitative cylinder, and is provided with a quantitative transfer depression, which is formed in the leading end thereof to a predetermined depth. The quantitative basket is configured to quantitatively receive the liquid according to the rectilinear reciprocation of the quantitative piston. | 04-22-2010 |
| 20100099174 | Method and Apparatus for Providing Power Management in Data Communication Systems - A blood glucose meter having a compact housing, a display unit disposed on the housing, the display unit including a display light source to illuminate the display unit, an input unit disposed on the housing, the input unit configured to provide input functions for the blood glucose meter, and a power source provided within the housing for providing power to the blood glucose meter, where the housing includes a port integrated on said housing configured to receive a blood glucose test strip, and corresponding methods of measuring blood glucose meter is provided. | 04-22-2010 |
| 20100112678 | ANALYTICAL TEST STRIP WITH MINIMAL FILL-ERROR SAMPLE VIEWING WINDOW - An electrochemical-based analytical test strip includes an electrically-insulating substrate, a patterned conductive layer disposed over the electrically-insulating substrate, a patterned insulating layer disposed over the patterned conductive layer, an enzymatic reagent layer disposed over the patterned conductive layer, a patterned adhesive layer disposed above the enzymatic reagent layer and a top layer disposed over the enzymatic reagent layer. In addition, the test strip has a sample-receiving chamber defined by the electrically-insulating substrate, the patterned conductive layer, the patterned insulating layer, the enzymatic reagent layer, the patterned adhesive layer and the top layer. The sample receiving chamber of the test strip has a working portion and a non-working portion and the top layer has a first portion and an opaque second portion. The first portion is configured such that a user can view the working portion of the sample-receiving chamber through the first portion of the top layer, while the opaque second portion is configured to preclude a user from viewing the non-working portion of the sample-receiving chamber. | 05-06-2010 |
| 20100129897 | BIOLOGICAL COMPONENT-MEASURING UNIT, BIOLOGICAL COMPONENT-MEASURING UNIT PACKAGE, MEDICAL SUPPORT INSTRUMENT KIT, AND MEDICAL SUPPORT INSTRUMENT KIT PACKAGE - A biological component-measuring unit, a package of a biological component-measuring unit, a medical support instrument kit, and a package of a medical support instrument kit, for improving workability and enabling the measurement of components of body fluids hygienically. The biological component-measuring unit comprising a substrate detachably mountable on a medical support device proper, fluid channels fixed to said substrate, the medical support device proper including a fluid transfer structure where fluids in the fluid channels flow in one direction, wherein the fluid channels comprise a biological component-measuring channel which is: attachable to and detachable from a body fluid-drawing channel for drawing a fluid that has been sampled through a body fluid sampler; capable of transferring the fluid in the biological component-measuring channel in one direction, in cooperation with the fluid transfer structure; provided with a biological component sensor for measuring a biological component in the fluid being transferred; and capable of discharging the fluid as a waste after measurement of the biological component. | 05-27-2010 |
| 20100144020 | DISPOSABLE DIAGNOSTIC KIT - Provided is a disposable diagnostic kit capable of diagnosing diseases. The disposable diagnostic kit includes a preprocessor, a target material reactor, and a microfluidic channel. The preprocessor filters target materials from a fluid containing various biomaterials. The target material reactor includes a diffraction grating on whose surface sensing materials reacting with the target materials are immobilized. Herein, a wavelength of light penetrated into the diffraction grating or a wavelength of light reflected by the diffraction grating varies depending on the target materials. The microfluidic channel moves the filtered fluid from the preprocessor to the target material reactor. | 06-10-2010 |
| 20100151560 | Compact disk based platform for separating and detecting immunomagnetic bead labeled cells - Disclosed is a disk based platform for separating and detecting cells that are labeled with immunomagnetic beads. A disk-like carrier board forms therein at least one flow channel structure, which includes an inner reservoir for receiving a sample fluid, an outer reservoir, and a plurality of micro flow channels arranged between and in fluid communication with the inner and outer reservoirs. When the disk-like carrier board spins, cells labeled with immunomagnetic beads are attracted by a magnetic attraction unit that is arranged above the disk-like carrier board and adjacent to the inner reservoir to thereby remain in the inner reservoir, and cells that are not so labeled are acted upon by a centrifugal force induced by the spinning of the disk-like carrier board to flow with the sample fluid from the inner reservoir through the micro flow channels into the outer reservoir. | 06-17-2010 |
| 20100159572 | DEVICE AND ASSOCIATED METHOD - A microfluidic device for detecting one or more molecules of interest comprising: a non-conductive substrate; wherein the non-conductive substrate is provided with a plurality of thermally active elements is provided. A method for selectively functionalizing a plurality of thermally active elements is also provided. | 06-24-2010 |
| 20100159573 | MICROFLUIDIC DILUTION DEVICE - Provided is a microfluidic dilution device that uses capillary force to dilute first and second fluids in a predetermined ratio. The microfluidic dilution device includes a channel plate, a cover plate, fluid chambers, and a confluence chamber. The fluid chambers are filled with first and second fluids in a predetermined ratio. First and second fluids flowing to the confluence chamber are diluted in a predetermined ratio. | 06-24-2010 |
| 20100159574 | MICROFLUIDIC DEVICE AND MICROFLUIDIC ANALYSIS EQUIPMENT - Provided are a microfluidic device and a microfluidic analysis equipment. The microfluidic device includes guides disposed along both edges, a lower plate including a flow path defined between the guides, and a movable upper plate moved along the guides on the lower plate and having a length less than that the flow path. A fluid flow can be simply accurately controlled by adjusting a position of the movable upper plate. As a result, the fluid can sufficiently react in the detection part and the reaction part. Therefore, effective reaction and detection can be realized using only a small amount of fluid, thereby improving sensitivity. In addition, due to the improved sensitivity, a washing process for removing materials that are not consumed in the reaction can be omitted. Also, the movable upper plate can be manually moved using a user's finger. | 06-24-2010 |
| 20100167385 | User interface features for an electronic device - A method is provided for controlling a display device of an electronic device. A data field may be displayed on the display device. An editing process may be executed that provides for editing of the data field displayed on the display device. The data field on the display device may be magnified relative to other portions of the display device when selected for editing according to the editing process. | 07-01-2010 |
| 20100178688 | ACOUSTIC WAVE BIOSENSOR FOR THE DETECTION AND IDENTIFICATION OF CHARACTERISTIC SIGNALING MOLECULES IN A BIOLOGICAL MEDIUM - An acoustic wave biosensor comprises a plurality of spaced apart electrodes disposed on a substrate of piezoelectric material and having a biolayer matched to a specific type of autoinducer signaling molecule to be detected. The biolayer comprises a layer of heterobifunctional molecules disposed on the electrodes and on the piezoelectric material between the electrodes, and a plurality of bioreceptor molecules which bind exclusively with the specific type of autoinducer signaling molecule to be detected. The bioreceptor molecules are supported by the layer of heterobifunctional molecules, and a hydrogel layer surrounds the bioreceptor molecules to support a three-dimensional structure thereof. The bioreceptor molecules can bind with the specific type of autoinducer signaling molecule to be detected, and the biolayer is reactive thereto such that corresponding autoinducer signaling molecules bind to the biolayer and detectably vary acoustic characteristics of the acoustic wave biosensor. | 07-15-2010 |
| 20100178689 | DEVICE FOR DECANTATION DEPOSITION OF CELLS ON AN ANALYSIS PLATE - A device includes a reception chamber ( | 07-15-2010 |
| 20100184200 | Cell culture device - The present invention relates to a cell culture device which includes: a cell culture container comprising a container body and a neck connecting to the container body wherein the container contains a top wall, a bottom wall having a first opening, and at least one side wall to define a cell culture zone, and an end of the neck has a second opening for cells or culture media being injected into the cell culture zone; a biosensor chip having a detective surface which faces the top wall of the cell culture container; and a fastening component for the biosensor chip being fastened in the first opening of the bottom wall. The cell culture of the present invention can be used for real-time detection of the cell growth and further for drug screening. | 07-22-2010 |
| 20100184201 | MEASURING UNIT FOR MEASURING CHARACTERISTICS OF A SAMPLE LIQUID, IN PARTICULAR VISCOELASTIC CHARACTERISTICS OF A BLOOD SAMPLE - The present invention is directed to a measuring unit, for measuring characteristics of a sample liquid, comprising a support member, having at least one upper bearing arm, with an upper bearing unit, at least one lower bearing arm, with a lower bearing unit, and a base, for being attachable to a respective measuring system; a shaft, having shaft toes and being rotatably supported about a rotation axis, by said upper bearing unit, and said lower bearing unit, wherein said upper bearing unit, said lower bearing unit, and said shaft toes form toe bearings, respectively; an interface member, having a detecting element, and a drive element, said interface member, being fixed on said shaft, and being connected to a coupling shaft, with a probe connector section, for measuring characteristics of said sample liquid; wherein said interface member, and the coupling shaft, are coaxially aligned with said shaft. | 07-22-2010 |
| 20100196999 | REAGENT VESSEL - Provided is a reagent vessel which is inserted into a measuring cassette for measuring a biological sample. The reagent vessel includes: a reagent storage unit including at least one space in which a reagent that is to react with the biological sample is stored; and an adhesive cover sealing up the at least one space in which the reagent is stored, and being stripped off to discharge the reagent from the at least one space when the reagent vessel is inserted into the measuring cassette. Therefore, since a plurality of reagents are poured simultaneously and automatically into a measuring cassette through a reagent vessel, it is possible to simplify manipulations and minimize a measuring time. Furthermore, it is possible to resolve problems regarding storage and distribution of reagents. | 08-05-2010 |
| 20100203621 | BIOSENSOR - A biosensor has the following elements: a diaphragm having a through-hole; a frame supporting the diaphragm and having a cavity; and pillars formed on the side of inner wall surface of the frame and on the surface of the diaphragm. This structure can suppress the occurrence of bubbles in the vicinity of the through-hole, and easily remove the remaining bubbles. Thus the measuring reliability of the biosensor can be improved. | 08-12-2010 |
| 20100210008 | Configurable Microfluidic Substrate Assembly - A microfluidic substrate assembly includes a substrate body having at least one fluid inlet port. At least one microscale fluid flow channel in the substrate is in fluid communication with the inlet port for transport of a fluid to be tested. The substrate body also has a plurality of sockets, with each of one or sockets configured to receive an operative component. At least one socket is in communication with the microscale fluid flow channel. | 08-19-2010 |
| 20100221815 | SUBSTRATES, DEVICES, AND METHODS FOR QUANTITATIVE LIQUID CRYSTAL ASSAYS - The present invention relates to the field of molecular diagnostics, and in particular to diagnostics based on a liquid crystal assay format. In particular, the present invention provided improved substrates and methods of using liquid crystal assays for quantitating the amount of an analyte in a sample. The present invention also provides materials and methods for detecting non-specific binding of an analyte to a substrate by using a liquid crystal assay format. | 09-02-2010 |
| 20100227382 | Nanoscale sensors - Various aspects of the present invention generally relate to nanoscale wire devices and methods for use in determining analytes suspected to be present in a sample, and systems and methods of immobilizing entities such as reaction entities relative to nanoscale wires. In one aspect, a nucleic acid, such as DNA, may be immobilized relative to a nanoscale wire, and in some cases, grown from the nanoscale wire. In certain embodiments, the nucleic acid may interact with entities such as other nucleic acids, proteins, etc., and in some cases, such interactions may be reversible. As an example, an enzyme such as telomerase may be allowed to bind to DNA immobilized relative to a nanoscale wire. The telomerase may extend the length of the DNA, for instance, by reaction with free deoxynucleotide triphosphates in solution; additionally, various properties of the nucleic acid may be determined, for example, using electric field interactions between the nucleic acid and the nanoscale wire. In another aspect, the invention provides systems and methods for attaching entities such as nucleic acids, receptors such as gangliosides, or surfactants to a nanoscale wire, for example, using aldehyde-producing reactions or hydrophobic interactions. In some aspects, certain systems and methods of the present invention may be used to determine an analyte suspected to be present in a sample, for example, a toxin, a virus, or a small molecule. Systems and methods of using such nanoscale wires are disclosed in other aspects of the invention, for example, within a microarray. Still other aspects of the invention include assays, sensors, kits, and/or other devices that include such nanoscale wires, methods of making and/or using functionalized nanoscale wires (for example, in drug screening or high-throughput screening), and the like. | 09-09-2010 |
| 20100233792 | Microdevices for Chemical Sensing and Chemical Actuation - The invention relates to sensors for detecting chemical and biological material and for chemical actuation. In particular, the sensors of the present invention incorporates membranes or beams that are deformable in the presence of chemical adsorption on its surface. The sensor of the present invention contains a polymeric membrane or beam ( | 09-16-2010 |
| 20100233793 | HEALTHCARE MANAGEMENT APPARATUS, HEALTHCARE MANAGEMENT METHOD, AND DISPLAY METHOD OF DETERMINATION RESULTS - A healthcare management apparatus for determining a health condition of subjects is provided. | 09-16-2010 |
| 20100240119 | MICROSEPARATION STRUCTURE AND DEVICES FORMED THEREWITH - A microseparation structure is provided that includes a top surface defining a first chamber. A second chamber is provided that is in fluid communication with the first chamber and characterized by a volume less than the volume of the first chamber. At least one hole extends in fluid communication with the second chamber to transmit fluids into a capillary draw void volume filled with a capillary draw-inducing agent such that liquid placed in the first chamber is drawn through the second chamber and through the hole to the capillary draw void volume filled with capillary draw-inducing agent. Particles of interest within the liquid are unable to pass into the hole and are therefore isolated within the second chamber. This structure is amenable to forming into a compact chromatographic filtration media made up of multiple such structures that is well suited for sealed testing for diseases such as malaria. | 09-23-2010 |
| 20100240120 | ANALYTICAL STRIP AND THE MANUFACTURING METHOD THEREOF - An analytical strip including a substrate and a channel structure is disclosed. A substrate has a flat surface and the channel is formed on the flat surface according to a predetermined pattern. The surface of channel structure is not lower than the surface of the substrate. The channel has a hollow-matrix conformation and the channel is more hydrophilic than the flat surface of the substrate is. The strip also contains a reaction material formed in the hollow-matrix. | 09-23-2010 |
| 20100248345 | PARTICLE FACILITATED TESTING - Magnetic particles are distributed across a fluid flow by applied magnetic field to interact with a test substance in fluid. Alternatively or additionally, particles, which may be magnetic, are combined with cells and energy, e.g. ultrasonic energy, is applied to cause the particles to create a lysate. Alternatively or additionally, the size of a quantity of magnetic particles is assessed by its impact on the tuning mechanism of a controlled oscillator that is affected by the particles. | 09-30-2010 |
| 20100248346 | ANALYZER - An analyzer comprising: a housing comprising a first space therein; a reagent accommodation section, disposed in the housing, comprising a second space therein for accommodating a reagent container containing a reagent, and an air induction port for inducting air from the first space to the second space; and a cooler for cooling the air which has been inducted from the first space through the air induction port into the second space, is disclosed. | 09-30-2010 |
| 20100248347 | DIAGNOSTIC SUPPORT APPARATUS FOR RENAL DISEASE AND COMPUTER PROGRAM PRODUCT - The present invention is to present a diagnostic support apparatus for renal disease, comprising: a red blood cell information obtainer for obtaining at least one of red blood cell numerical information representing the number of red blood cells in a urine sample, and red blood cell morphological information representing morphology of the red blood cells in the urine sample; a quantitative value information obtainer for obtaining at least one of quantitative value information representing amount of protein component in the urine sample, and quantitative value information representing amount of lipid component in the urine sample; and a diagnostic support information output unit for outputting diagnostic support information related to renal disease based on information obtained by the red blood cell information obtainer and information obtained by the quantitative value information obtainer. | 09-30-2010 |
| 20100255564 | Apparatus for Preventing Electrical Shock in Devices - A device for preventing electrical shock from a device with electrical interfaces. A shutter or other barrier associated with the device that physically prevents access or contact to one of the electrical interfaces while another electrical interface is in use. | 10-07-2010 |
| 20100255565 | Apparatus for Preventing Electrical Shock in Devices - A device for preventing electrical shock from a device with electrical interfaces. A shutter or other barrier associated with the device that physically prevents access or contact to one of the electrical interfaces while another electrical interface is in use. | 10-07-2010 |
| 20100255566 | Apparatus for Preventing Electrical Shock in Devices - A device for preventing electrical shock from a device with electrical interfaces. A shutter or other barrier associated with the device that physically prevents access or contact to one of the electrical interfaces while another electrical interface is in use. | 10-07-2010 |
| 20100261263 | UP AND DOWN CONVERSION SYSTEMS FOR PRODUCTION OF EMITTED LIGHT FROM VARIOUS ENERGY SOURCES - A system for energy upconversion and/or down conversion and a system for producing a photostimulated reaction in a medium. These systems include 1) a nanoparticle configured, upon exposure to a first wavelength λ | 10-14-2010 |
| 20100273244 | APPARATUS FOR PERFORMING COUNTS WITHIN A BIOLOGIC FLUID SAMPLE - An apparatus for enumerating one or more specific elements within a biologic fluid sample is provided. The apparatus includes a first planar member that is transparent, and a second planar member. The members are separated from one another by a substantially uniform height, and the height is sized relative to the specific elements within the sample such that the specific elements non-uniformly distribute within the sample upon introduction into the chamber. | 10-28-2010 |
| 20100273245 | REACTION VESSEL, REACTION VESSEL LIQUID INTRODUCING DEVICE, LIQUID INTRODUCING AND REACTION MEASURING DEVICE, AND LIQUID INTRODUCING DEVICE - The invention relates to a reaction vessel, a reaction vessel liquid introducing device, a liquid introducing and reaction measuring device, and a liquid introducing device, and is directed to being able to perform temperature control of a liquid stored within the reaction vessel with a high accuracy and faithful responsiveness. The reaction vessel comprises: a storage chamber in which a liquid is storable, that has an opening part; a reaction chamber that is formed thinner or narrower than the storage chamber; and at least one flow passage that communicates between the storage chamber or the exterior and the reaction chamber. The reaction vessel is formed such that it is connectable to a liquid introducing section provided externally, and the liquid can be introduced into the reaction chamber by connecting to the liquid introducing section. | 10-28-2010 |
| 20100273246 | WHOLE SMOKE EXPOSURE APPARATUS - An apparatus includes a smoke emitting section which emits smoke containing particulate matter, a dilution section for diluting the smoke emitted by the smoke emitting section, a clean air unit which supplies clean air to the dilution section, at least one chamber which incorporates a cell-adhered surface and into which the smoke diluted by the dilution section is introduced, and an exhaust section for exhausting the smoke from the chamber and the dilution section. A smoke flow in the chamber is shut off to make the smoke settle down in the chamber and expose the cell-adhered surface to the smoke. | 10-28-2010 |
| 20100279393 | MICRO CHIP DEVICE | 11-04-2010 |
| 20100279394 | METHOD OF COMPONENT ASSEMBLY ON A SUBSTRATE - A method of component assembly on a substrate, and an assembly of a bound component on a substrate. The method comprises the steps of forming a free-standing component having an optical characteristic; providing a pattern of a first binding species on the substrate or the free standing component; and forming a bound component on the substrate through a binding interaction via the first binding species; wherein the bound component exhibits substantially the same optical characteristic compared to the free-standing component. | 11-04-2010 |
| 20100291665 | BIOCOMPATIBLE THREE DIMENSIONAL MATRIX FOR THE IMMOBILIZATION OF BIOLOGICAL SUBSTANCES - The present invention relates to a method of producing a solid coated carrier carrying biological material. Furthermore, the invention relates to a solid coated carrier to which biological material is attached and uses of the solid coated carrier for the preparation of a medical product. Moreover, the invention provides a method for the contacting, filtration or cleaning of blood, lymph or liquor cerebrospinalis of a patient, a method for the diagnosis of a disease and a diagnostic composition. | 11-18-2010 |
| 20100297743 | COENZYME-BINDING GLUCOSE DEHYDROGENASE - The present invention provides a microorganism-derived soluble coenzyme-binding glucose dehydrogenase which catalyzes a reaction for oxidizing glucose in the presence of an electron acceptor, has an activity to maltose as low as 5% or less, and is inhibited by 1,10-phenanthroline. The invention also provides a method for producing the coenzyme-binding glucose dehydrogenase, and a method and a reagent for measuring employing the coenzyme-binding glucose dehydrogenase. According to the invention, the coenzyme-binding glucose dehydrogenase can be applied to an industrial field, and a use becomes possible also in a material production or analysis including a method for measuring or eliminating glucose in a sample using the coenzyme-binding glucose dehydrogenase as well as a method for producing an organic compound. It became also possible to provide a glucose sensor capable of accurately measuring a blood sugar level. Therefore, it became possible to provide an enzyme having a high utility, such as an ability of being used for modifying a material in the fields of pharmaceuticals, clinical studies and food products. | 11-25-2010 |
| 20100311149 | BIOSENSOR - Disclosed herein is a biosensor. The biosensor includes a measuring layer configured to measure whether reaction to a biological sample has occurred. An upper cover is disposed on a top of the measuring layer, and is provided with an open window configured to allow a measurement area of the measuring layer to be exposed and an upper protrusion configured to protrude from an outer portion of the open window in a direction in which the upper protrusion is coupled to a lower panel. The lower panel is disposed below the measuring layer, and is provided with a lower protrusion which protrudes between the open window and the upper protrusion of the upper cover so that the lower protrusion is spaced apart from the upper protrusion by a gap and which presses the measuring layer so that a top of the measuring layer upwardly protrudes from the open window. | 12-09-2010 |
| 20100311150 | CELL PROCESSING DEVICE - In a closed system having a large number of containers connected via pipes, a leakage of a liquid from the closed system can be more reliably detected by a convenient and inexpensive method. Provided is a cell processing device ( | 12-09-2010 |
| 20100311151 | Blood Glucose Tracking Apparatus and Methods - A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand-held computer. Electronics determine the amount of glucose present in a sample of body fluid, when the test strip is positioned in the receptacle and the body fluid is placed on a test strip, and communicate the glucose amount to the hand-held computer via the connector portion. | 12-09-2010 |
| 20100317092 | COMPONENT MEASURING APPARATUS - A component measuring apparatus is provided with a case having a cylindrical case main body and a cover arranged to cover the base end opening section of the case main body; a chip mounting section for mounting a chip; a light measuring section for detecting a prescribed component; a printed board whereupon a control section having a function of controlling the operation of the light measuring section is arranged; a liquid crystal display device; a battery arranging section for arranging a battery provided on the cover; an O-ring arranged between the case main body and the light measuring section on the leading end section of the case main body; and an O-ring arranged between the case main body and the cover on the base end opening section of the case main body. Sealing of inside the case is ensured by the O-ring. | 12-16-2010 |
| 20100330661 | Peptides for Detection of Antibody to Ehrlichia ewingii - The invention provides compositions and methods for the detection and quantification of | 12-30-2010 |
| 20110027872 | CANTILEVER FOR MEASURING INTRA-CELLULAR AND INTER-CELLULAR MICROSPACES - A cantilever for measuring intra-cellular and inter-cellular microspaces of the present invention includes a support portion, a lever portion provided to the support portion so as to protrude therefrom, and a probe portion provided near a free end of the lever portion. The probe portion includes a conductive probe made of a carbon-based material, and an insulating film to coat a periphery of the conductive probe. | 02-03-2011 |
| 20110027873 | MICRO-NANO FLUIDIC BIOCHIP FOR ASSAYING BIOLOGICAL SAMPLE - Disclosed is a micro-nano fluidic biochip for assaying a biological sample comprising a first substrate, a second substrate and a third substrate which are sequentially stacked from bottom to top, wherein an upper channel assembly disposed on the second substrate is coupled with the lower channel assembly provided on the first substrate, to form a microfluidic channel, and the microfluidic channel has nano interstices formed at both sides thereof, the nano interstices having a height less than that of the center of the channel. | 02-03-2011 |
| 20110045577 | Fabrication of conductive pathways, microcircuits and microstructures in microfluidic networks - Disclosed herein are a variety of microfluidic devices and solid, typically electrically conductive devices that can be formed using such devices as molds. In certain embodiments, the devices that are formed comprise conductive pathways formed by solidifying a liquid metal present in one or more microfluidic channels (such devices hereinafter referred to as “microsolidic” devices). In certain such devices, in which electrical connections can be formed and/or reformed between regions in a microfluidic structure; in some cases, the devices/circuits formed may be flexible and/or involve flexible electrical components. In certain embodiments, the solid metal wires/conductive pathways formed in microfluidic channel(s) may remain contained within the microfluidic structure. In certain such embodiments, the conductive pathways formed may be located in proximity to other microfluidic channel(s) of the structure that carry flowing fluid, such that the conductive pathway can create energy (e.g. electromagnetic and/or thermal energy) that interacts withy and/or affects the flowing fluid and/or a component contained therein or carried thereby. In other embodiments, a microsolidic structure may be removed from a microfluidic mold to form a stand-alone structure. In certain embodiments, the solid metal structures formed may interact with light energy incident upon a structure or may be used to fabricate a light-weight electrode. Another aspect of the invention relates to the formation of self-assembled structures that may comprise these electrically conductive pathways/connections. | 02-24-2011 |
| 20110045578 | METHOD OF MANUFACTURING BIOSENSOR AND BIOSENSOR PRODUCED THEREBY - Provided are a biosensor and a method of manufacturing the same which can reduce an amount of liquid specimen required for measurement (a required amount of the liquid specimen), and conduct measurement with higher accuracy. In the biosensor, the liquid specimen is developed on a development layer by using chromatography and a test substance in the liquid specimen is measured. By reducing the thickness of the development layer (to 20 μm to 135 μm), the required amount of the liquid specimen is reduced. The thickness of the development layer is controlled to a smaller thickness thus, so that the required amount of the liquid specimen can be reduced in response to the measurement of a test substance in each liquid specimen in a state in which the accuracy of analysis is properly kept. | 02-24-2011 |
| 20110065172 | DIRECT MIXING AND INJECTION FOR HIGH THROUGHPUT FLUIDIC SYSTEMS - A system and method of mixing and injecting discrete sample mixtures into a flow cytometer or other sample analysis apparatus may generally comprise a sample injection guide coupling a liquid handling apparatus with a sample analysis apparatus and facilitating injection of discrete sample mixtures into a fluidic system of the apparatus. | 03-17-2011 |
| 20110070633 | ANALYTICAL TOOL, ANALYTICAL TOOL PACK, CARTRIDGE INCLUDING PLURALITY OF PACKS, METHOD OF MAKING ANALYTICAL TOOL PACK, ANALYZER, AND MECHANISM FOR TAKING OUT OBJECT - The present invention relates to an analytical tool pack ( | 03-24-2011 |
| 20110091963 | High resolution flow cytometer - High resolution particle differentiation process and separation system that provides enhanced resolution of particles based upon selected particle characteristics. In particular, the system may include an enhanced resolution flow cytometer. In an embodiment, the invention can include at least one fluid source conduit ( | 04-21-2011 |
| 20110091964 | CELL MANIPULATION OBSERVATION APPARATUS - An introducing position arrangement unit arranges a position of a cell into which a substance is introduced, of the cells in a culture dish mounted on a stage, specified by a specification unit to a predetermined cell manipulation position in a viewing field of an observation unit by stage driving. A cell manipulation unit introduces an introduction substance mixed in a culture fluid in the culture dish into the cell by making a hole on a cell membrane of the cell moved to the predetermined cell manipulation position. A diagram display unit displays a diagram associated with an observation range which is a range of the culture dish observable by the observation unit and also displays a cell manipulation range which is a cell manipulation enabled range and a position currently observed by the observation unit to be superimposed on the diagram associated with the observation range. | 04-21-2011 |
| 20110091965 | CELL MANIPULATION OBSERVATION APPARATUS - An introducing position arrangement unit arranges a position of a cell into which a substance is introduced, of the cells in a culture dish mounted on a stage, specified by a specification unit to a predetermined cell manipulation position in a viewing field of an observation unit by driving the stage. A cell manipulation unit introduces an introduction substance mixed in a culture fluid in the culture dish into the cell by making a hole on a cell membrane of the cell moved to the predetermined cell manipulation position by the introducing position arrangement unit. A display unit displays introduced cell information including positional information of the cell indicative of the specified position and introduction substance information indicative of the introduction substance. | 04-21-2011 |
| 20110097788 | NANO AND MICRO-TECHNOLOGY VIRUS DETECTION METHOD AND DEVICE - The invention relates to methods and devices for detecting the presence of a particle of interest (hereinafter an analyte particle) in a fluid. A detection device exemplary of the present invention filters a sample of the fluid to remove particles larger than the analyte particles. A reagent solution, containing reagent particles smaller than the analyte particles, is then added to the sample. The reagent particles will react with the analyte particles, if any are present, to form reagent-analyte complexes which are larger than the analyte particles. The sample is then filtered a second time to remove particles the same size as or smaller than the analyte particles. The sample is then tested for the presence of reagent-analyte complexes to detect the presence of the analyte particle in the fluid. | 04-28-2011 |
| 20110097789 | TUBE PORTS AND RELATED CONTAINER SYSTEMS - A tube port includes a tubular first stem having an interior surface and an exterior surface extending between a first end and a longitudinally spaced apart second end. The interior surface bounds a passage that longitudinally extends through the first stem. The tube port also includes a flange encircling and radially outwardly projecting from the first end of the first stem. The flange and the first stem are integrally formed as a unitary member comprised of a flexible elastomeric material having a durometer on a Shore A scale with a value of less than 90. | 04-28-2011 |
| 20110111486 | BIOREACTOR SYSTEMS AND DISPOSABLE BIOREACTOR - The present invention is in the field of cell bioreactors, and specifically in the field of disposable bioreactors. | 05-12-2011 |
| 20110124095 | Method and apparatus for high throughput diagnosis of diseased cells with microchannel devices - The method and apparatus of the present invention detects changes in cell biomechanics caused by any of a variety of diseases and conditions. In one embodiment, the method and apparatus of the invention detect infection of red blood cells. In one embodiment, the invention is a method and apparatus comprising a microfluidic channel with a constriction, for trapping infected red blood cells while allowing healthy red blood cells to deform and pass through the channel. In another embodiment, the invention comprises a suspended microchannel resonator for detecting and counting red blood cells at the constriction of the microfluidic channel. | 05-26-2011 |
| 20110159578 | Multiple-input Analytical System - The present disclosure provides an automated sample processing system that can receive samples in different first and second formats and process both sample formats. The disclosure also provides a human papillomavirus testing apparatus. The apparatus has a first input to receive first test specimens in the form of pre-processed cervical samples, and a second input to receive unprocessed cervical samples. A first subsystem prepares second test specimens from the unprocessed cervical samples, and a second subsystem selectively processes and tests first specimens, second test specimens, or first and second test specimens to determine the presence of one or more human papillomavirus indicators. | 06-30-2011 |
| 20110177584 | ACOUSTIC WAVE SENSOR AND DETECTION METHOD USING ACOUSTIC WAVE SENSOR - An acoustic wave sensor having significantly increased sensitivity and excellent sensing reproducibility and stability includes a piezoelectric substrate, an acoustic wave element including an electrode disposed on the piezoelectric substrate, and a reactive membrane which overlies the acoustic wave element and which is reduced in mass by direct or indirect chemical reaction with a measured substance. The measured substance is detected such that a change in mass applied to the acoustic wave element from the reactive membrane is detected by a change in frequency. | 07-21-2011 |
| 20110183407 | APPARATUS AND METHOD FOR TIP ALIGNMENT IN MULTIWELL PLATES - Apparatuses and methods of aligning at least one tip of a tip manifold with a plurality of wells of a multiwell plate. The tip manifold includes a plate, at least one tip depending from the plate, a first tip alignment pin depending from the plate, and a second tip alignment pin depending from the plate. The second tip alignment pin opposes the first tip alignment pin. The multiwell plate includes a body defining a plurality of non-porous wells for holding biological material, a first alignment hole, and a second alignment hole. The second alignment hole opposes the first alignment hole. | 07-28-2011 |
| 20110183408 | REAGENT CARTRIDGE FOR MICROORGANISM DETECTION APPARATUS - A reagent cartridge for a microorganism detection apparatus includes a plurality of reagent vessels, a support plate, and side plates, wherein the reagent vessels are integrally connected with each other in parallel by the support plate, and a group of the plurality of the reagent vessels is surrounded by the side plates; the reagent cartridge further includes an independent reagent vessel instead of at least one of the plurality of the reagent vessels and separately therefrom; and an engagement portion, wherein the engagement portion engages the independent reagent vessel in the engagement portion so as to be universally attached and detached, and to be in parallel with the plurality of the reagent vessels. | 07-28-2011 |
| 20110189762 | ELECTROCHEMICAL SENSOR AND METHOD FOR MANUFACTURING - The present disclosure relates to a sensor including an elongated member including at least a portion that is electrically conductive. The elongated member includes a sensing layer adapted to react with a material desired to be sensed. An insulating layer surrounds the elongated member. The insulating layer defines at least one access opening for allowing the material desired to be sensed to enter an interior region defined between the elongated member and the insulating layer. The insulating layer has an inner transverse cross-sectional profile that is different from an outer transverse cross-sectional profile of the elongated member. The difference in transverse cross-sectional profiles between the elongated member and the insulating layer provides channels at the interior region defined between the insulating layer and the elongated member. The channels extend generally along the length of the elongated member and are sized to allow the material desired to be sensed to move along the length of the sensor. | 08-04-2011 |
| 20110195490 | CARTRIDGE FOR APPARATUS FOR CHEMICALLY ANALYZING BLOOD AND APPARATUS USING THE SAME - The present invention provides a cartridge for an apparatus for analyzing blood chemistry that is used for medical treatment, and automatically analyzes and records data needed for medical service, such as the concentrations of electrolytes, the partial pressures of gases, and the concentrations of metabolites, or the volume ratio of red blood cells contained in blood. The apparatus for analyzing blood chemistry of present invention includes: an apparatus frame having a compartment; a cartridge that is inserted into the compartment of the apparatus frame and includes a sensor card, a solution valve unit, and a blood introducing unit; a controller that receives a signal generated from the sensor card and processes the signal; a lever for the blood introducing unit is connected to the apparatus frame; a power transmitting unit that is provide to the apparatus frame and transmits power of the lever for the blood introducing unit to open/close the blood introducing unit of the cartridge; a solution transporting unit that is provided to the apparatus frame and transports the solutions in the cartridge; and driving units that actuates the solution valve unit of the cartridge by the controller and opens or close the tubing flowing of the solutions. | 08-11-2011 |
| 20110201098 | Polymer Replicated Interdigitated Electrode Array for Bio(Sensing) Applications - A sensor is disclosed. In one embodiment, the sensor includes an insulating substrate comprising a first zone, a second zone, and an intermediate zone, where the intermediate zone comprises a portion of the second zone that overlaps the first zone. The sensor further comprises a first electrode in the first zone that comprises a first plurality of fingers of a conductive material, a second electrode in the second zone that comprises a second plurality of fingers of the conductive material that are interdigitated with the first plurality of fingers, a plurality of three-dimensional isolation structures, and a plurality of shadow zones, wherein each shadow zone is adjacent to at least one isolation structure and is substantially free of conductive material. The plurality of isolation structures may comprises hills and/or channels. | 08-18-2011 |
| 20110207205 | CHIP FOR INSPECTING TOXICITY AND EFFICACY - Disclosed herein is a chip for inspecting toxicity and efficacy, including: a first substrate including fitting holes formed at corners thereof; and a second substrate including gap forming members formed at corners thereof corresponding to the fitting holes to form a gap between the first substrate and the second substrate, and protrusions formed on the gap forming members corresponding to the fitting holes and fitted in the fitting holes. The chip for inspecting toxicity and efficacy is advantageous in that alignment of the chip can be easily performed, in that problems with the emission of fluorescence or the penetration of measuring light in the chip can be solved, and in that the cost of producing the chip can be reduced. | 08-25-2011 |
| 20110207206 | NON-SHRINKABLE SOL-GEL-POLYMER HYBRID AND METHODS THEREOF - A composite including a cross-linked interpenetrating network of an organic polymer including an alcohol adduct of, for example, a glycidyl ether substituted acrylate or epoxy substituted acrylate; and a sol-gel polymer. The composite having a low or no-shrinkage characteristic, and a method for making and using the composite, as defined herein. | 08-25-2011 |
| 20110217762 | PHOTO-ACOUSTIC DETECTION DEVICE AND METHOD - An example method for detecting an analyte in a sample of a bodily fluid comprises the steps of exposing the bodily fluid sample to electromagnetic energy to cause a thermoelastic expansion in the analyte, and detecting a photoacoustic signal in the sample that results from the thermoelastic expansion. | 09-08-2011 |
| 20110217763 | A SEMICONDUCTOR FOR MEASURING BIOLOGICAL INTERACTIONS - An apparatus and method are disclosed for electrically directly detecting biomolecular binding in a semiconductor. The semiconductor can be based on electrical percolation of nanomaterial formed in the gate region. In one embodiment of an apparatus, a semiconductor includes first and second electrodes with a gate region there between. The gate region includes a multilayered matrix of electrically conductive material with capture molecules for binding target molecules, such as antibody, receptors, DNA, RNA, peptides and aptamer. The molecular interactions between the capture molecules and the target molecules disrupts the matrix's continuity resulting in a change in electrical resistance, capacitance or impedance. The increase in resistance, capacitance or impedance can be directly measured electronically, without the need for optical sensors or labels. The multi-layered matrix can be formed from a plurality of single-walled nanotubes, graphene, or buckeyballs or any kind of conductive nanowire, such as metal nanowires or nanowires made from conductive polymers. | 09-08-2011 |
| 20110223651 | APPARATUS FOR TESTING ELECTRICAL ACTIVITY FROM A BIOLOGICAL TISSUE SAMPLE - An apparatus ( | 09-15-2011 |
| 20110229960 | TAPE MAGAZINE FOR A HAND-HELD DEVICE - The present invention concerns a tape magazine especially for a hand-held device for analysing a body fluid with a test tape that can be unwound from a storage unit and wound onto a waste unit where the waste unit can be driven in order to wind forward the test tape. The invention provides that a lock which keeps the test tape under tension is integrated in the tape magazine at least on the storage unit. The present invention also concerns a hand-held device with such a tape magazine. The present invention also concerns a hand-held device with a mechanical drive for the test tape and a disposable hand-held device with polymer-based electronic components. | 09-22-2011 |
| 20110229961 | ACTIVE MICROFLUIDIC SYSTEM FOR IN VITRO CULTURE - Described herein are systems and methods for microfluidic cell support, including a microfluidic cell support system and methods for its use. The microfluidic cell support system can include a base assembly, a manifold assembly, and a microfluidic celltray including a microcirculatory path in fluid communication with the manifold assembly. The microfluidic celltray can be microfluidically closed and mechanically open. In some aspects the microfluidic celltray contains one or more cell wells containing fluid for supporting living cell(s). In some aspects, the microcirculatory path provides active fluid flow between a microfluidic inflow channel and a microfluidic outflow channel. | 09-22-2011 |
| 20110236962 | Calibratable sensor unit for reaction vessels - The present invention relates to a calibratable sensor unit for a reaction vessel, such as for example a fermenter ( | 09-29-2011 |
| 20110236963 | SYSTEM AND METHOD FOR ANALYTE MEASUREMENT - A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed. | 09-29-2011 |
| 20110244558 | SAMPLE ANALYZER AND INFORMATION WRITING METHOD - A sample analyzer comprising: a reagent container set section for setting a reagent container; a reader/writer configured to read out an information from the recording medium attached to the reagent container set in the reagent container set section and configured to write an information on the recording medium; a writing instruction section configured to issue an instruction to write the information on the recording medium; and a controller configured to control the reader/writer to write the information on the recording medium attached to the reagent container set in the reagent container set section if the kind information read out from the recording medium indicates the specific reagent and the writing instruction section has issued the writing instruction. Also, a method of writing information on a recording medium attached to a reagent container. | 10-06-2011 |
| 20110263006 | INTEGRATED TEST STRIP CONTAINER WITH RETAINING INSERT - A blood glucose meter for providing easy access to test strips and measuring blood glucose, a disposable and removable cartridge for providing easy access to test strips, and methods of manufacturing and utilization thereof are disclosed. The blood glucose meter for providing easy access to test strips and measuring blood glucose has a disposable and removable cartridge, a retaining member which releasably retains the test strips in a stacked configuration, and a housing. The disposable and removable cartridge has a rigid lid attached to a flexible body. | 10-27-2011 |
| 20110263007 | DEVICE, KIT AND METHOD FOR PULSING BIOLOGICAL SAMPLES WITH AN AGENT AND STABILISING THE SAMPLE SO PULSED - A device and kit for pulsing a biological sample with a pulsing agent is disclosed. The biological sample so pulsed is subsequently stabilized and the device or kit provides a control reaction. Applications for the described device and kit are found in the field of medical diagnostics, particularly immunology. | 10-27-2011 |
| 20110269221 | FLOW CHANNEL DEVICE, COMPLEX PERMITTIVITY MEASURING APPARATUS, AND DIELECTRIC CYTOMETRY SYSTEM - A flow channel device, a complex permittivity measuring apparatus, and a dielectric cytometry system are provided which can improve the measurement accuracy. A constriction portion having a constricted space is disposed between an inflow port and an outflow port of a flow channel. Electrodes are arranged between the inflow port and the constriction portion and between the outflow port and the constriction portion. The conductance of the constriction portion at a low-limit frequency is less than the combined conductance of an inflow channel portion and an outflow channel portion. The capacitance of the constriction portion at a high-limit frequency is less than the combined capacitance of the inflow channel portion and the outflow channel portion. | 11-03-2011 |
| 20110275143 | Microfluidic Bubble Logic Devices - Fluid-based no-moving part logic devices are constructed from complex sequences of micro- and nanofluidic channels, on-demand bubble/droplet modulators and generators for programming the devices, and micro- and nanofluidic droplet/bubble memory elements for storage and retrieval of biological or chemical elements. The input sequence of bubbles/droplets encodes information, with the output being another sequence of bubbles/droplets or on-chip chemical synthesis. For performing a set of reactions/tasks or process control, the modulators can be used to program the device by producing a precisely timed sequence of bubbles/droplets, resulting in a cascade of logic operations within the micro- or nanofluidic channel sequence, utilizing the generated droplets/bubbles as a control. The devices are based on the principle of minimum energy interfaces formed between the two fluid phases enclosed inside precise channel geometries. Various devices, including logic gates, non-volatile bistable memory, ring oscillators, bubble synchronizers, analysis chips, and printers have been designed. | 11-10-2011 |
| 20110281342 | HAND-HELD DEVICE FOR MEASURING AN ANALYTE CONCENTRATION IN A SAMPLE OF A BODY LIQUID - A hand-held device for measuring an analyte concentration in a sample of a body liquid includes a display means for displaying measured values; a measured-value storage for storing measured values; a measuring unit for generating measured values through measurements of the analyte concentration; a clock; a control unit for generating measured value datasets, each containing a measured value supplied by the measuring unit as well as the date and hour of the measurement by which the measured value was obtained, and for writing them into the measured-value storage; and operating elements that can be actuated by the user to set the clock, in which case the control unit will generate a time-correction dataset indicating the amount and direction of the setting effected. The control unit writes time-correction datasets into the measured-value storage so that a chronologically ordered sequence is generated containing time-correction datasets and measured value datasets. | 11-17-2011 |
| 20110281343 | BIOREACTOR WITH RODS ARRAYED FOR CULTURING ANCHORAGE-DEPENDENT CELLS - The instant invention employs an array of rods packed into a suitable chamber to support the culture, e.g., maintenance and/or growth of anchorage-dependent cells that effectively increases the surface area available for cell culture. Adherent cells are seeded and propagated on the surface of the rods. Each rod is accommodated with spacer devices that serve to make it immobile and ensure uniform access to liquid growth medium while minimizing abrasive damage to shear-sensitive cells. Spacer devices of various designs allow the rods to be packed and anchored into bioreactors, e.g., perfusion chambers with flow-through ports or into closed roller bottle-type chambers. Simple monomeric designs of the rods and spacer devices allow for relative ease of manufacture and assembly including solid or hollow rods or supports constructed of fibers or strings consisting of flexible tissue culture treated material that is held fast by threading or knotting between suitable spacer devices with eyelets, holes or other anchoring fixtures. In some embodiments, the rods are composed of tissue culture-treated plastic packed into culture chambers as prepackaged, sterile, disposable single use items. | 11-17-2011 |
| 20110281344 | Detection Device - A detection device and a detection method are disclosed. The detection device comprises a sample inlet ( | 11-17-2011 |
| 20110287528 | Devices, Systems, and Methods Related to Analyte Monitoring and Management - Analyte monitoring devices, systems, and methods are provided that relate to: enabling different application features on a data processing device for analyte monitoring devices with different analyte monitoring features; programming analyte monitoring devices in advance; personalizing an analyte monitoring device; graphically representing a remaining insulin level in a user body; and graphically representing analyte measurement related data for on-demand readings; protecting access to feature of an analyte monitoring device. | 11-24-2011 |
| 20110294197 | MODULE FOR DETECTING ANALYTES IN FLUIDS AND CHIP HAVING THE SAME - Disclosed is a module for rapidly detecting analytes in fluids with high effectiveness and a chip having the module. The module includes a microchannel, which has a filtering zone for removing noise materials and a reaction zone wherein labeling reaction and immobilization reaction for detection of analytes are performed, sample fluid moving through the microchannel due to capillary floating. In a case where the chip having the module is used in detecting analytes in fluids, it is possible to minimize dead volume of sample fluid so that high effective volume ratio can be implemented. Therefore, the chip can be used in detecting analytes from the minimum amount of sample fluid. | 12-01-2011 |
| 20110294198 | DISPOSABLE CHAMBER FOR ANALYZING BIOLOGIC FLUIDS - An apparatus for analyzing biologic fluid is provided that includes first and second planar members, and at least three separators. At least one of the first planar member and second planar member is transparent. The separators are disposed between the planar members, and each individually has a height. The separators collectively having a mean height, and separate the planar members to form a chamber having a height extending between the planar members. At least one of the first planar member, second planar member, or separators is sufficiently deformable when the first planar member and second planar member are drawn toward each other by capillary force from a biologic fluid quiescently residing within the chamber to cause the mean chamber height to be substantially equal to the mean height of the separators. | 12-01-2011 |
| 20110300618 | SEMI-AUTOMATED DEVICE FOR SINGLE PARAMETER AND MULTI-PARAMETER PHENOTYPING OF CELLS - A single-use device that produces a readily interpretable, visual presentation of biomaterial, enabling single parameter and multi-parameter characterizing of said biomaterial by means of visual inspection, particularly for immunophenotyping. In one embodiment, the device uses antibody coated microspheres which are adapted to bind to specific types of cells. An arrangement of uniquely molded components, which may be plastic or other suitable material, are assembled so as to provide a sequential procedure capable of incubating a suspension comprised of antibody coated microspheres, biomaterial, and liquid suspension agents. Following incubation, the invention further removes liquids from said suspension, and provides for rinsing the incubated retentate and for removing said rinsing liquids from the incubated retentate. The invention further provides for affixing the incubated retentate onto a standard glass microscope slide to enable phenotyping of incubated biomaterial (e.g., cells) by means of visual inspection or other analyses that can be performed from a glass slide. | 12-08-2011 |
| 20110300619 | IN VITRO DETERMINATION OF ANALYTE LEVELS WITHIN BODY FLUIDS - A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band. | 12-08-2011 |
| 20120015429 | QUANTITATIVE LATERAL FLOW SYSTEM AND ASSAY - The present invention relates to a lateral flow assay and system, including a test strip, for detection and quantification of analytes in samples, such as samples containing cells and fluid. In general, according to the present invention, a test strip for a lateral flow assay for detection of at least one analyte in a sample comprises: (1) a chromatographic strip, a sample filter, a fluid-impermeable barrier, and means for providing a mobilizable detectable agent that is capable of binding to the at least one analyte or to the capture agent after capturing the analyte to the chromatographic strip such that the mobilizable detectable agent migrates through the chromatographic strip and contacts sample that has passed through the sample filter and also has migrated through the chromatographic strip. The test strip allows detection with or without quantitation of an analyte in a sample containing whole cells. | 01-19-2012 |
| 20120045825 | DIAGNOSTIC TEST TAPE FOR LIQUID SAMPLES - A diagnostic test tape for liquid samples is provided comprising a flexible transport tape and a plurality of test fields applied to the transport tape that are distributed in the longitudinal direction of the tape, where said test fields comprise a detection layer and a spreading net spanning the detection layer for a planar uptake of liquid sample, wherein the spreading net is formed from a lattice-like fabric comprising fabric threads that cross at right angles. In order to prevent the fabric from arching up under tape tension it is proposed that the fabric is oriented obliquely to the transport tape such that all fabric threads run obliquely to the longitudinal direction of the tape. | 02-23-2012 |
| 20120058546 | MULTIPLE SURFACE ACOUSTIC WAVE SENSOR SYSTEM - Provided is a multiple SAW sensor system capable of sensing a plurality of target materials in the SAW sensor with a single detector by using a multiplexer. According to the multiple SAW sensor system, the target materials in SAW sensors may be sensed with a single detector, thereby avoiding unnecessary power loss. Also, a plurality of target materials in a sample may be sensed, thereby reducing a waste of the sample. | 03-08-2012 |
| 20120064612 | MICROFLUIDIC DEVICES FOR FLUID MANIPULATION AND ANALYSIS - The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis. | 03-15-2012 |
| 20120064613 | Monitoring Methods and Apparatus - A device for remote management of patients suffering from heart failure and hypertension can measure one or more biomarker. The device aids in monitoring the efficacy and safety of treatment in such patients. | 03-15-2012 |
| 20120077257 | Cell measurement system - A cell measurement system measures changes of frequency and transepithelial electrical resistance of a tested cell sample. The cell measurement system includes a quartz crystal sensing module, an oscillation module, a periodic wave-generation module, a low-pass filtration module, and a control module. The cell measurement system of the present invention can simultaneously measure changes of frequency and transepithelial electrical resistance of a tested cell sample during cell growth so that the growth level and healthy condition of the cells and degree of a monolayer completion of the cells can be determined. | 03-29-2012 |
| 20120077258 | DIAGNOSTIC DEVICE - A diagnostic device as a first electrode formed by a noble metal that is not attackable by acid, and a second electrode that is formed of silver. The first and second electrodes are at least partially immersed in a nutrient solution contained in a container, into which a tissue sample can be introduced. An electrical voltage is applied between the first and second electrodes, and a change in an electrical variable between the electrodes is measured when ammonia is present. The diagnostic device allows fast screening of tissue samples for Helicobacter pylori. | 03-29-2012 |
| 20120088293 | ANALYZER - An analyzer comprising: a first specimen holder configured to hold a plurality of first specimen containers; a conveying assembly for conveying the first specimen containers held in the first specimen holder; a second specimen holder arranged at a position higher than an upper end of the first specimen containers held in the first specimen holder; a holder moving assembly for moving the second specimen holder so as to pass the upper side of at least one of the first specimen containers held in the first specimen holder; a container transferring assembly for transferring at least one of the first specimen containers from the first specimen holder to the second specimen holder; and a controller for controlling the holder moving assembly and the container transferring assembly, is disclosed. | 04-12-2012 |
| 20120094367 | Blood analysis apparatus - The present invention relates to a blood analysis apparatus X for measuring concentrations of glucose and glycohemoglobin in blood. The blood analysis apparatus X is configured to perform the concentration measurement of the glucose and the glycohemoglobin by one sampling of blood | 04-19-2012 |
| 20120115211 | Apparatus for Testing the Quality of a Fluid Sample - Apparatus for testing the quality of a fluid sample comprising a body defining an interior space including a primary chamber and one or more secondary chambers, the apparatus having a first configuration in which it is arranged to hold at least some of the fluid sample in the primary chamber and a second configuration in which it is arranged to isolate a first portion of the fluid sample within the one or more secondary chambers whilst retaining a second portion of the fluid sample in the primary chamber. | 05-10-2012 |
| 20120122198 | BIOSENSOR MANUFACTURING METHOD - A biosensor having a first conductive component is described, wherein the first conductive component includes at least one boundary formed by a first processing technique and at least one boundary formed by a second processing technique not the same as the first processing technique. The biosensor can also have a second conductive component including at least one boundary formed by the first processing technique and at least one boundary formed by a third processing technique not the same as the first processing technique. Further, the biosensor has a third conductive component including at least one boundary formed by the second processing technique and at least one boundary formed by the third processing technique not the same as the second processing technique. | 05-17-2012 |
| 20120129248 | ASSAY TOOLS AND METHODS OF USE - The present invention provides assay tools for the detection of biological or chemical activity in a sample. The assay tools of the invention provide direct detection using a positive signal generated on a surface of the assay tool. These assay tools provide improved methods for detection and/or identification of multiple agents (e.g., enzymes) in a sample, analysis of substrate specificity of such agents, and binding affinities and specificities of such agents. Upon activity a component is released from a first immobilised construct and then captured by a capture surface. At least two different immobilised constructs are used. | 05-24-2012 |
| 20120135507 | BIOCHIP MODULE WITH CERAMIC LAMINATE STRUCTURE AND METHOD OF MANUFACTURING THE SAME - The present disclosure provides a biochip module having a ceramic laminate structure which uses advantages of ceramic and enables a reduction in a chip area, and a method of manufacturing the same. The biochip module includes a first ceramic layer mixing bacterial water with magnetic beads to which ligands capturing bacteria are attached, a second ceramic layer separating the magnetic beads capturing bacteria from the water, and a third ceramic layer detecting the number of bacteria captured by the magnetic beads. | 05-31-2012 |
| 20120135508 | SYSTEM AND METHOD FOR ANALYTE MEASUREMENT - A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed. | 05-31-2012 |
| 20120135509 | SENSOR DEVICES - The present invention relates to a sensor device for measuring a level of an analyte of interest in a fluid, such as body fluid (for example blood, plasma, urine, interstitial fluid, saliva), a method of manufacturing a sensor device, a reagent film for use in a sensor, a method of manufacturing a reagent film for use in a sensor, a method of conducting an assay using a sensor, a method of calibrating a measurement from a sensor, a method of calibrating a batch of sensors, a meter for use with a sensor and a kit comprising a meter and a sensor according to the invention. A first aspect of the invention provides a sensor device for measuring a level of an analyte of interest In a fluid comprising: a flowpath for the fluid; on the flowpath, a reagent for the analyte of interest adjacent to an internal standard comprising a first predetermined amount of a first calibration analyte; and further wherein the reagent and the predetermined amount of a first calibration analyte are in dry form. A second aspect of the invention provides a device comprising: a first calibration electrode having the first predetermined amount of first calibration analyte and reagent for the analyte of interest located thereon; a first working electrode having reagent for the analyte of interest thereon, and further wherein the first calibration electrode lies upstream of the first working electrode. | 05-31-2012 |
| 20120142084 | GRAPHICAL INTERFACE FOR ANALYTE METER - Diagnostic systems include a meter that is configured to receive a test sensor during a testing procedure. The diagnostic systems also include a computing device coupled to the meter. The test sensor receives a fluid sample during the testing procedure. The meter includes a measurement system that determines a measurement of a concentration of an analyte in the fluid sample. The computing device receives and processes the measurement from the meter. The computing device has enhanced processing and presentation capabilities that provide visual and/or audio instructions on how to operate the diagnostic system, especially when an error or exceptional condition arises. | 06-07-2012 |
| 20120156763 | Apparatus and Methods for Using Biological Material to Discriminate an Agent - An apparatus and methods for using biological material to discriminate an agent. In one embodiment of the present invention, the method includes the steps of providing at least one cell, exposing at least one cell to an agent, measuring the response of the cell to the agent in terms of a physical quantity related to at least one of the cellular physiological activities of the cell, and identifying the agent from the measured response. The method further includes the step of quantifying the agent from the measured response. | 06-21-2012 |
| 20120156764 | Automated Analyzer - The automatic analyzer repeatedly performs a first processing operation for creating a pretreated specimen with a pretreatment solution in a first reaction cell. The analyzer also repeatedly performs a second processing operation for creating a reacted specimen by reacting the pretreated specimen with a reagent in a second reaction cell. In a first control operation, a turntable is rotated through a first angle in a first direction and halted. In a second control operation, the turntable is rotated through a second angle in a second direction and halted. The second reaction cell is spaced by a second angle in a first direction from the first reaction cell. The turntable is so rotated that the first and second reaction cells are halted at least in first, second, and third positions. | 06-21-2012 |
| 20120156765 | FLUID FILTERING DEVICE - The invention relates to a fluid filtering device comprising a filter ( | 06-21-2012 |
| 20120164716 | BIOCHIP SENSOR - Small and extremely small molecules and ions or atoms may be detected with the novel device with exceptional sensitivity. The detection is implemented in a simple manner by the known acoustic resonator FBAR or by means of other technologies that measure the physical properties of the filled layer. The permeability of substances (e.g. active ingredients) through membranes such as cell membranes, lipid bilayers, and cell walls can be examined by combining a sensor with the reservoir and the membrane. | 06-28-2012 |
| 20120171757 | CARTRIDGE AND SENSOR-DISPENSING INSTRUMENT - A disposable cartridge adapted to be used with a sensor-dispensing instrument comprises a housing, test sensors, a mechanical mechanism and moveable seals. The housing forms at least one opening therethrough. The test sensors are stacked in the housing. The test sensors are adapted to assist in testing at least one analyte. The mechanical mechanism is adapted to urge the test sensors in a first direction. One of the test sensors is positioned for ejection from the cartridge. The moveable seals is adapted to be in a closed position that seals the at least one opening so as to provide a substantially moisture-proof and a substantially air-tight cartridge, and one of the moveable seals is adapted to be in an open position that allows one of the test sensors to be moved therethrough. | 07-05-2012 |
| 20120178151 | UNITARY PLASTIC CONDUCTIVITY SENSOR - A contacting-type conductivity sensor includes an electrically-insulative plastic body and a plurality of electrodes. The plurality of conductive electrodes is disposed in the plastic body. Each electrode is constructed of plastic and fused with the electrically-insulative plastic body. A method of manufacturing the conductivity sensor is provided along with a single-use bioreactor employing the sensor. | 07-12-2012 |
| 20120196354 | ANALYSIS DEVICE - The analysis device includes a main body, an insertion slot into which a sensor piece is inserted in a manner such that the sensor piece sticks out from the main body in a measurement operation, and a pair of projections spaced apart from each other in a y-direction, with the insertion slot present between the projections. Each of the projections protrudes outwardly in an x-direction and has a height overlapping the insertion slot in a z-direction. | 08-02-2012 |
| 20120214223 | Worm Culture Systems - Devices and methods are disclosed for the containment and culture of worms, and the preparation of composts, vermicomposts, and castings from organic and inorganic wastes. | 08-23-2012 |
| 20120244606 | MICROORGANISM NUMBER-MEASURING APPARATUS - A microorganism number-measuring apparatus includes a container holder holding container that accommodates a liquid into which microorganisms are released, power supply unit applying a microorganism-collecting voltage and a microorganism number-measuring voltage to measurement electrode that is dipped in container held by the container holder, and reuse prevention unit that makes measurement electrode burn out after a measurement operation thereof. With this configuration, it is possible to prevent improper reuse of the measurement electrode. | 09-27-2012 |
| 20120258523 | PROCESS FOR REMEDIATING BIOFOULING IN WATER SYSTEMS WITH VIRULENT BACTERIOPHAGE - Bacterial contamination of industrial water systems lead to biofouling by biofilms and corrosion from bacterial induced corrosion. This invention provides a method for control of fouling and contamination of industrial water systems caused by bacteria. Prevention or reduction of process interruptions and general contamination, fouling and corrosion is achieved by the destruction of targeted problematic bacteria with naturally occurring, non-engineered bacteriophage virulent for targeted bacteria. The invention also provides for in-situ confirmation of the proper identification of target bacteria and a mobile laboratory adapted to implement the method. | 10-11-2012 |
| 20120264201 | CULTURE APPARATUS - A culture apparatus comprising: an inner box configured to form a culture chamber; an outer box configured to cover the inner box; a fan configured to circulate gas inside the culture chamber through an air passage provided in the inner box within the culture chamber; a first through hole configured to penetrate a wall configuring a part of the air passage in the inner box; a second through hole configured to penetrate the wall and disposed at a position at which a flow velocity of the gas circulated through the air passage by the fan is lower than a flow velocity of the gas around the first through hole; a connecting pipe configured to connect the first through hole and the second through hole outside of the inner box; and a sensor configured to detect a concentration of the gas flowing in the culture chamber. | 10-18-2012 |
| 20120276621 | Multi-Way Sorter System and Method - Provided herein are improved multi-way cell sorter systems and methods. For example, provided are systems and methods for the collection of cells that are sorted in multiple directions. The systems and methods allow for the construction of a multi-way sorter (e.g., a ten-way sorter in the space that currently only allows four-way sorting). In addition the device may actively sense the arrival of drops (with cells of interest) at a sample tube, and trigger an alarm when the drops' arrivals deviate from an expected pattern. | 11-01-2012 |
| 20120288921 | SOLAR POWERED SPECTRAL PHOTOSYNTHETIC BIOREACTOR SYSTEM FOR CULTURING MICROALGAE AT HIGH DENSITY - A solar powered spectral photosynthetic bioreactor system for culturing microalgae at high density, the system comprising a photobioreactor and further comprising a solar collector, optical fiber, an illuminant device within the photobioreactor, and a residual gas absorption device and culture medium separation and recovery device each connected to the photobioreactor; the illuminant device having one end connected to a spectral light intensity adjusting device installed above the photobioreactor; the adjusting device connected to the solar collector via the optical fiber; a gas distributor provided between the underside of the illuminant device and a base part of the photobioreactor; the distributor connected to an output end of a gas mixing device. This system can effectively improve utilization of solar energy, lower external electrical power consumption, and resolve the problems of solar energy being intermittent and unstable in nature and difficult to collect, ensuring continuous and stable culturing of microalgae. | 11-15-2012 |
| 20120288922 | APPARATUS FOR FACILTIATING EVALUATING MIGRATION OF CELLS IN VITRO - Method and apparatus for processing a cell culture are provided. The method includes establishing a cell culture within a holding device having one or more wells, each well holding a cell culture, and including a well substrate with at least one electrode in contact with the cell culture; periodically applying at least one electrical pulse to the at least one electrode to prevent cells from attaching to and achieving confluence over the at least one electrode while allowing cells to attach to and achieve confluence over other portions of the well substrate; and discontinuing the periodically applying of the at least one electrical pulse to the at least one electrode after cells have achieved confluence over the other portions of the well substrate, and thereafter, monitoring the cell culture to monitor migration of cells over the electrode(s) from the other portions of the well substrate. | 11-15-2012 |
| 20120295340 | SEPARATION AND CONCENTRATION OF BIOLOGICAL CELLS AND BIOLOGICAL PARTICLES USING A ONE-DIMENSIONAL CHANNEL - This document discloses, among other things, a method and system for a substrate having a bypass region for fluid flow. The substrate includes a plurality of fluid flow channels with each channel configured to concurrently allow fluid flow while precluding passage of a target particle or object. | 11-22-2012 |
| 20120315690 | SYSTEMS AND METHODS FOR PARTICLE CLASSIFICATION AND SORTING - A particle analysis system includes an inlet; an inertial focusing microchannel disposed in a substrate and having a downstream expanding region at a distal end, where the inlet is connected to a proximal end of the microchannel; a plurality of outlets connected to the microchannel at the downstream expanding region; a plurality of fluidic resistors, where each fluidic resistor is connected to a respective outlet; and a particle analyzer configured to measure a size and a position of particles in the microchannel. A particle sorting system includes an inlet; an inertial focusing microchannel disposed in a substrate and having a downstream expanding region at a distal end, where the inlet is connected to a proximal end of the microchannel; a plurality of outlets connected to the microchannel at the downstream expanding region; and a plurality of fluidic resistors, where each fluidic resistor is connected to a respective outlet. | 12-13-2012 |
| 20120315691 | MICRO-CALORIMETER APPARATUS - A micro-calorimeter apparatus includes a thermostated housing ( | 12-13-2012 |
| 20120329141 | SELECTIVE PARTICLE CAPTURE AND COLLECTION DEVICE - A particle processing device includes a chamber and at least one capturing structure. The chamber is connected to a first port and a second port to provide a space between the first and second ports for flowing of a fluid having a particle. The capturing structure is provided in the chamber to form a fluidic channel, wherein the fluidic channel has a first opening and a second opening and a capturing region is formed between the first and second openings such that the capturing region has a changeable sectional shape for capturing the particle in the fluid flowing from the first port to the second port. | 12-27-2012 |
| 20130017595 | ANALYTICAL APPARATUS AND DETECTION METHOD EMPLOYED IN ANALYTICAL APPARATUSAANM Yamamoto; ShuheiAACI MitoAACO JPAAGP Yamamoto; Shuhei Mito JPAANM Sano; MinoruAACI HitachinakaAACO JPAAGP Sano; Minoru Hitachinaka JPAANM Nemoto; AkiyukiAACI MitoAACO JPAAGP Nemoto; Akiyuki Mito JPAANM Fujioka; MichiruAACI HitachinakaAACO JPAAGP Fujioka; Michiru Hitachinaka JP - Disclosed is an analytical apparatus wherein a container is automatically transferred and the container is automatically closed with a cap member, said analytical apparatus being provided with a suitable mechanism that reliably closes the container. The analytical apparatus is provided with an optical sensor composed of at least one pair of a light source ( | 01-17-2013 |
| 20130040374 | CHEMICAL SENSOR - To provide a chemical sensor that can dissolve analytes in a gas in a liquid using a simple method, the chemical sensor comprising a sensor support section; a gas injection hole through which a gas containing an analyte is injected; a sample collection section in which the analyte contained in the gas injected through the gas injection hole is collected; a sample delivery section through which the analyte collected in the sample collection section is delivered; a sample reaction section including a reactant that causes a predetermined reaction with the analyte delivered through the sample delivery section; and a detection section in which the analyte reacted with the reactant in the sample reaction section is detected, wherein the sample collection section includes a Peltier element that liquefies water vapor contained in the gas injected through the gas injection hole. | 02-14-2013 |
| 20130045527 | REAGENT DELIVERY SYSTEM - A delivery apparatus for selectively delivering one or more liquid reagents into a reaction or test chamber ( | 02-21-2013 |
| 20130052722 | Blood Glucose Monitoring Kit - A blood glucose monitoring kit includes a case constructed in the form of a bi-fold wallet which comprises an upper flap and a lower flap that are connected together through a fold. Blood glucose monitoring electronics are preferably integrated directly into the upper flap of the case, the electronics including a printed circuit board (PCB), a test port mounted on the PCB and a display mounted on the PCB. Preferably, the upper flap is provided with an opening through which the test port is externally accessible. Additionally, the upper flap is provided with a window through which the display is externally visible. A pouch is secured onto the inner surface of the lower flap and is sized and shaped to retain a plurality of disposable test components. | 02-28-2013 |
| 20130089919 | Biosensor Chip with Nanostructures - A biosensor chip with nano-structures. The biosensor chip includes a RF biosensor, comprising an isolated substrate; a ground plane; a filtering circuit; at least one cell detection area with nano-structures and a protection layer. The RF biosensor can detect the existence of the cancer cells, high frequency biological effects and the cells relationship between transfers by noninvasive method. The RF biosensor according to the invention can provide high accuracy and sensitivity in cancer cells detection. | 04-11-2013 |
| 20130095563 | METHOD AND SYSTEM FOR DETECTING AN ANALYTE - Aspects and embodiments are directed to methods and systems of detecting an analyte present in the environment. More particularly, this disclosure relates to methods and systems of detecting a threatening or dangerous analyte that may increase survivability of an individual or group of individuals. | 04-18-2013 |
| 20130102062 | MICROCHIP FOR NUCLEIC ACID AMPLIFICATION REACTION AND METHOD OF PRODUCING THE SAME - Provided is a microchip for a nucleic acid amplification reaction, including a well configured to function as a reaction site of the nucleic acid amplification reaction, and the well has a center portion and a marginal portion, a substance anchored in a form that the substance is eccentrically-located less at the center portion and much at the marginal portion of the well, in which the substance is at least a part of a substance for the nucleic and amplification reaction. | 04-25-2013 |
| 20130122575 | DEVISE TO PRODUCE ALCOHOL, BIO FUELS AND OTHER COMPOUNDS WITH A SEA BASED FERMENTOR - A device, system, and method to produce alcohol and Bio fuels from bulky organic matter with a Sea based Fermentor with low cost per unit volume, formed from a plastic separator barrier which is flexible plastic film, a solar based distillation still with vacuum assist are disclosed. In one embodiment, a device includes a Fermentor coupled to a inlet channel made of plastic film separator, converted to Continuous process Fermentation channel, a Bio Gas digester to generate methane, a floating platform having engine, pumps, centrifuge and sterilization unit and a crane, a water treatment unit formed from plastic film is provided | 05-16-2013 |
| 20130130362 | POWER SPECTRAL DENSITY CHEMICAL AND BIOLOGICAL SENSOR - A surface acoustic wave (SAW) based sensor device and system for detecting the presence of and measuring the concentration of chemical and biological analytes in vapor and liquid phase can include inherent temperature compensation and the capability to operate in a wired mode or in a wireless mode with the ability to measure the distance of the sensor from the wireless transceiver (in addition to measuring temperature and the chemical and/or biological analytes of interest). This device can also monitor changes in state of thin films, including but not limited to sensing glassy to rubbery transitions in polymers, and measurement of the kinetics of chemical and/or biological processes occurring at the surface of the device. Coding, time, and frequency diversity can be included in the device structure to enable production of groups of individually identifiable sensor devices capable of operating simultaneously within the field of view of a wireless transceiver. | 05-23-2013 |
| 20130171723 | Mixing Bag with Integral Sparger and Sensor Receiver - A mixing bag for use in bioprocessing in which a fluid is received and agitated using an internal fluid-agitating element driven by an external motive device is disclosed. The bag may include an integral sparger and sensor receiver. Related methods are also disclosed. | 07-04-2013 |
| 20130177969 | BIOSENSORS AND BIO-MEASUREMENT SYSTEMS USING THE SAME - A biosensor is provided. The biosensor is used to sense a biological sample and has a code representing features of the biosensor. The biosensor includes a substrate and a conductive layer. The conductive layer is disposed on a first side of the substrate and includes a first conductive loop and a second conductive loop. The first conductive loop is formed between a first node and a second node and has a first impedance. The second conductive loop is formed between the second node and a third node and has a second impedance. The code is determined according to a comparison result between the second impedance and the first impedance. | 07-11-2013 |
| 20130183746 | BIO-CHIP MODULE AND DEVICE FOR MEASURING BIO-CHIP - There is provided a bio-chip module including: a first substrate including a plurality of projections formed on a first face thereof and made of a plastic material, the plurality of projections having a bio-material attached thereto; and a second substrate including a plurality of through holes into which the projections are inserted, the second substrate being combined with the first face of the first substrate. | 07-18-2013 |
| 20130183747 | CELL PROCESSING APPARATUS, SAMPLE PREPARATION APPARATUS, AND CELL ANALYZER - A cell processing apparatus includes a storage container that contains liquid L including a biological sample; a filter that prevents a first cell C | 07-18-2013 |
| 20130183748 | DISPERSING FEEDSTOCKS AND PROCESSING MATERIALS - Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can convert feedstock materials to a sugar solution, which can then be fermented to produce ethanol. Biomass feedstock is dispersed in a liquid medium and then saccharified. | 07-18-2013 |
| 20130183749 | SYSTEMS, APPARATUS, METHODS AND ARTICLES FOR USE IN SANITIZATION OR DISINFECTION - Various devices allow for sanitization or disinfection by exhausting a dry fog biocide agent into an ambient environment. A nebulizer, for instance a vibrator that oscillates or vibrates at ultrasonic frequencies, nebulizes a biocide agent, for instance chlorine dioxide, peracetic acid, hydrogen peroxide, to create the dry fog. Such devices may withdraw the dry fog or biocide agent from the ambient environment after some period of time. Operational parameters of the devices may be tracked or monitored. Each device may implement tracking or monitoring. Additionally or alternatively, a separate tracking or monitoring system may track or monitor the operational parameters of one or more devices. Tracking or monitoring may include exception reporting, as well as other reporting. | 07-18-2013 |
| 20130196421 | MARKER FOR READINGS TAKEN FROM ALTERNATIVE SITE TESTS - A meter for determining the concentration of an analyte in a fluid sample comprises a memory device, electrical circuitry and a detection device for distinguishing between an alternative site test and a standard site test. The memory device is adapted to store information. The electrical circuitry is adapted to determine the analyte concentration of the fluid sample located on a test sensor. The electrical circuitry is in electronic communication with the memory device. The electrical circuitry communicates the determined analyte concentration to the memory device for storage. | 08-01-2013 |
| 20130217101 | Apparatus for Embedding Tissue Samples - A histology tissue embedding apparatus including a reservoir for an embedding medium and an outlet valve connected to the reservoir through which the embedding medium is dispensable, and including trigger means which control the operation of the outlet valve, the trigger means having a rest position in which the outlet valve is closed, wherein the rest position of the trigger means in relation to the outlet valve is adjustable. | 08-22-2013 |
| 20130217102 | SYSTEMS AND METHODS FOR THERMAL ACTUATION OF MICROFLUIDIC DEVICES - A microfluidic processing device includes a substrate defining a microfluidic network. The substrate is in thermal communication with a plurality of N independently controllable components and a plurality of input output contacts for connecting the substrate to an external controller. Each component has at least two terminals. Each terminal is in electrical communication with at least one contact. The number of contacts required to independently control the N components is substantially less than the total number of terminals. Upon actuation, the components typically heat a portion of the microfluidic network and/or sense a temperature thereof. | 08-22-2013 |
| 20130224844 | STRUCTURED POLYDIORGANOSILOXANE POLYAMIDE CONTAINING DEVICES AND METHODS - Devices including a polydiorganosiloxane polyamide containing material having a microstructured surface are disclosed herein. Such devices can optionally include a flex circuit attached to the microstructured surface and can be useful, for example, in fluid handling applications. | 08-29-2013 |
| 20130230907 | HIGH-THROUGHPUT SENSORIZED BIOREACTOR FOR APPLYING HYDRODYNAMIC PRESSURE AND SHEAR STRESS STIMULI ON CELL CULTURES - A bioreactor ( | 09-05-2013 |
| 20130236952 | SYSTEM FOR PROCESSING BIOMASS - A system for processing biomass using anaerobic digestion includes an anaerobic acidification reactor having an inlet for biomass and an outlet for acidified biomass, and an anaerobic settling chamber having an inlet for receiving the acidified biomass from the anaerobic acidification reactor wherein an acidified liquid biomass and a sludge biomass is formed. The anaerobic settling chamber includes a first outlet for the acidified liquid biomass, a second outlet for the sludge biomass and a third outlet for gaseous biogas effluent. The system further includes an anaerobic methane synthesis reactor for anaerobic microbial conversion of acidified liquid biomass into biogas and processed liquid biomass, having an inlet for receiving the acidified liquid biomass and a first outlet for gaseous biogas effluent and a second outlet for the processed liquid biomass. | 09-12-2013 |
| 20130267014 | DEVICE FOR ANALYZING THE EFFECT OF A GASEOUS MEDIUM ON A BIOLOGICAL TEST SYSTEM USING AN EXTRACELLULAR METABOLIZATION SYSTEM - The invention relates to a method for analyzing the effect of a gaseous medium on a biological test system using an extracellular metabolization system. The method consists of the following steps: a biological test sample is cultivated on a permeable carrier, the gaseous medium is guided over the surface of the biological test system in order to form an exposition atmosphere over the biological test system, the extracellular metabolization system is added to a conservation medium and the permeable carrier is brought into contact with a conservation medium that comprises the extracellular metabolization system below the permeable carrier, in such a manner that the extracellular metabolization system only passes through the permeable carrier and that the biological test system is not submerged by the conservation medium containing the extracellular metabolization system. | 10-10-2013 |
| 20130273642 | DEVICE AND METHOD FOR DETECTION OF ANALYTES - The present invention provides assays and devices for detection of substances in liquid samples. The assays and devices utilize passive diffusion between a porous material and a porous membrane containing a specific binding pair member to enable detection of the substance of interest. | 10-17-2013 |
| 20130288345 | SUBSTRATE PROBE, ENZYME-ACTIVITY DETECTION METHOD BY A MULTI-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE METHOD AND ENZYME-ACTIVITY IMAGING METHOD - An object of the present invention is to provide a substrate probe capable of detecting enzyme activity with high accuracy and a method for detecting the enzyme activity by a multi nuclear magnetic resonance method using the substrate probe. Multi-dimensional nuclear magnetic resonance is performed by using a substrate probe, which is used for measuring enzyme activity by a multi-dimensional nuclear magnetic resonance method and characterized by containing a enzyme recognition site that is selectively recognized by an active-state enzyme, as at least one constitutional unit, and a group to which at least three nuclear magnetic resonance active nuclei each having a nuclear spin and a different resonance frequency are connected, being present specifically to the enzyme recognition, thereby detecting presence of the substrate probe and the enzyme activity. Alternatively, imaging of the enzyme activity is performed by a multi-dimensional nuclear resonance imaging method. | 10-31-2013 |
| 20130288346 | LINEARLY SCALABLE SINGLE USE BIOREACTOR SYSTEM - Disclosed is a single-use bioreactor bag design providing substantially equivalent maximum shear rate at the impeller tip and average or bulk shear rate over a range of power per unit working volume and rpm needed for bioculture processing. The uniformity in shear profile of the bag design providing a unique advantage when used as a scale-down or scale-up platform. Also disclosed is a linearly scalable, single-use, bioreactor system for use in carrying out a scalable biomanufacturing process, the system comprising two single-use bioreactor bags of different volumes, wherein the ratio H/D of the height of the working volume H to the diameter D of the tank, or of the bag is equal to about 1.5, and the bulk shear in each of the bags is substantially constant. The disclosed small scale system models larger scale systems from both a shear/scalability/performance basis and also from a validation and regulatory basis. In summary, the 10 L bioreactor system disclosed provides for “linear scalability” by using the same or substantially simulating the same vessel geometry, gas sparging system, impeller shape and type, polymer composition of the flexible bag/components, process control system, and shear rates as larger 50-5000 L systems. | 10-31-2013 |
| 20130344577 | LIQUID CRYSTAL BASED SENSOR DEVICES FOR DETECTING TOXINS, BACTERIA AND THEIR ACTIVITIES - A liquid crystal based sensor device for detecting analytes. A method of manufacturing liquid crystal based sensor devices for detecting analytes. A method for at least one of (i) detecting analytes with a liquid crystal based sensor device; (ii) detecting the activity of analytes; and (iii) detecting screening compounds binding to analytes and/or modifying their activity. | 12-26-2013 |
| 20140011267 | BIOGAS PRODUCING SYSTEM - A disintegrating system for treatment of organic material may include multiple disintegrating units, each having an inlet for receiving material, and an outlet for outputting treated material. A first inlet of a first disintegrating unit may be configured to receive organic material, and a first feedback pipe may be connected between the outlet of the first disintegrating unit and the inlet of a second disintegrating unit. An outflow of the disintegrating system may be connected to the outlet of at least the first disintegrating unit, wherein the sum of the introduced material is available at the outflow. | 01-09-2014 |
| 20140017772 | BIOSENSOR - A biosensor includes a flexible foil with an electrode layer positioned on the foil. An adhesive layer is positioned on the foil layer, and a first photo-definable hydrogel membrane is positioned over the electrode layer and the adhesive layer. A second photo-definable hydrogel membrane with an immobilized bio-recognition element is positioned over the first hydrogel membrane in contact with the electrode layer through an opening in the first hydrogel membrane. | 01-16-2014 |
| 20140073039 | DIRECT SENSING BIOFETS AND METHODS OF MANUFACTURE - The present disclosure provides a biological field effect transistor (BioFET) and a method of fabricating a BioFET device. The method includes forming a BioFET using one or more process steps compatible with or typical to a complementary metal-oxide-semiconductor (CMOS) process. The BioFET device includes a plurality of micro wells having a sensing gate bottom and a number of stacked well portions. A bottom surface area of a well portion is different from a top surface area of a well portion directly below. The micro wells are formed by multiple etching operations through different materials, including a sacrificial plug, to expose the sensing gate without plasma induced damage. | 03-13-2014 |
| 20140073040 | System And Method For Interfacing Sensors To A Sterile Flow Stream - A system and method for interfacing non-sterile sensors to a sterile flow stream is disclosed. Typically, sensors cannot be sterilized in the same manner as other components of the flow stream. This results in complex processes to incorporate a sterilized sensor into a sterilized flow stream. By introducing a separation membrane, the desired sensor can be interfaced to the sterile flow stream. By doing so, the sensor need not be sterile, only sufficiently clean. The membrane separates the sterile environment within the flow stream from the sensor, while still permitting the sensor to function. | 03-13-2014 |
| 20140073041 | ANALYZING DEVICE - A feature of an analyzing device is that a peeling portion ( | 03-13-2014 |
| 20140087451 | ACOUSTIC WAVE (AW) SENSING DEVICES USING LIVE CELLS - In one embodiment according to the invention, there is provided a method of sensing a response of a living cell or virus to a change in conditions. The method comprises applying an essentially constant external electromotive force that causes oscillation of an acoustic wave device at essentially constant amplitude and frequency under steady state conditions. The acoustic wave device has attached at least one living cell or virus. A combined oscillating system including the acoustic wave device and the living cell or virus exhibits a fundamental frequency and at least one harmonic frequency of the combined oscillating system. The living cell or virus is exposed to a change in an environmental condition while oscillating the combined oscillating system under the essentially constant external electromotive force, whereby a response of the living cell or virus to the change in environmental condition will be indicated by a change in at least one of frequency and amplitude of the oscillation of at least one harmonic frequency of the combined oscillating system. | 03-27-2014 |
| 20140127791 | DIAGNOSTIC DEVICE - A diagnostic device as a first electrode formed by a noble metal that is not attackable by acid, and a second electrode that is formed of silver. The first and second electrodes are at least partially immersed in a nutrient solution contained in a container, into which a tissue sample can be introduced. An electrical voltage is applied between the first and second electrodes, and a change in an electrical variable between the electrodes is measured when ammonia is present. The diagnostic device allows fast screening of tissue samples for | 05-08-2014 |
| 20140147912 | BIO-SENSOR - A bio-sensor configured with a lower substrate including a plurality of electrode portions, an insulating layer, a spacer layer, and an upper substrate provided on the spacer layer is provided. The bio-sensor includes a first sample injection portion provided between the upper substrate and the lower substrate along a longitudinal direction in which a sample is introduced and a second sample injection portion that is connected with the first sample injection portion in a direction substantially longitudinal direction, and formed larger than a sample inlet of the first sample injection portion. | 05-29-2014 |
| 20140147913 | Test Element Analysis System with Contact Surfaces Coated with Hard Material - The invention concerns a test element analytical system for the analytical examination of a sample, especially a body fluid, comprising at least one test element with one or more measuring zones and contact areas located on the test element, in particular electrodes or conductor paths, the sample to be examined being brought into the measuring zone to carry out an analysis in order to determine a characteristic measured quantity for the analysis, and an evaluation instrument with a test element holder for positioning the test element in a measuring position and a measuring device for measuring the characteristic change, the test element holder containing contact elements with contact areas which enable an electrical contact between the contact areas of the test element and the contact areas of the test element holder, characterized in that one of these contact areas is provided with an electrically conductive hard material surface. | 05-29-2014 |
| 20140154785 | METHOD FOR MAKING POLYMER SINGLE NANOWIRES AND SENSORS UTILIZING THE SAME - A method of fabricating polymer single nanowires, comprising the steps of: spin coating a polymethylmethacrylate resist onto a silicon wafer patterned with at least one gold electrode pair; creating a nanochannel using e-beam lithography between each pair of the at least one gold electrode pairs; placing the silicon wafer into an aniline monomer polymerization solution; reacting the polymerization solution to give a coated wafer and a polyaniline film; and cleaning the coated wafer of polymethylmethacrylate resist and polyaniline film to give at least one gold electrode pair with a connecting polymer single nanowire. | 06-05-2014 |
| 20140162348 | ELECTRICAL MEASURING CONTAINER, ELECTRICAL MEASURING APPARATUS AND ELECTRICAL MEASURING METHOD - There is provided an electrical measuring container of a biological sample in a liquid phase, including at least a biological sample holding section configured to accommodate a biological sample in a liquid phase and made of a resin, and an electrical conductive section fixed to the biological sample holding section. In a state in which a portion of the electrical conductive section is buried in the biological sample holding section, the biological sample holding section and the electrical conductive section are integrally formed with each other. | 06-12-2014 |
| 20140170735 | SYSTEMS AND METHODS FOR MULTI-ANALYSIS - Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample. | 06-19-2014 |
| 20140199757 | ATOMIC LAYER DEPOSITION INVERTED PASSIVATED SURFACE ACOUSTIC WAVE SENSOR FOR EARLY DETECTION OF BIOFILM GROWTH - A surface acoustic wave (SAW) biofilm sensor includes a transmitting electric to acoustic wave transducer defining an upper surface and a lower surface, a receiving acoustic wave to electric transducer defining an upper surface and a lower surface, a piezoelectric film layer defining an upper surface and a lower surface, and a passivation film layer defining an upper surface and a lower surface. Portions of the lower surface of the piezoelectric film layer are disposed on the upper surface of the transmitting electric to acoustic wave transducer and on the upper surface of the receiving acoustic wave to electric transducer, and the lower surface of the passivation film layer is disposed on the upper surface of the piezoelectric film layer such that the upper surface of the passivation film layer is configured to enable contact with a biofilm. | 07-17-2014 |
| 20140220666 | Self Contained In-Vitro Diagnostic Device - A portable apparatus for measuring a glucose level of a user having: a card-like member; a processor within the card-like member; at least one glucose sensor comprising a reagent, the glucose sensor generating a signal indicative of a measured glucose level upon application of a blood sample to the glucose sensor, wherein the glucose sensor is fixed to the card-like member and operably coupled to the processor; and at least one cover alterable between a first position in which the glucose sensor is covered and a second position in which the glucose sensor is exposed for use. | 08-07-2014 |
| 20140242681 | PHOTOBIOREACTOR - A photobioreactor system may include a one or more fluidly connectable tubes for growing or producing microorganisms or biomass such as microalgae. The system may include either a single tube loop or an array of tubes. A first fluid may be held in the tube or tubes, and an inlet port may be provided for introducing a second fluid into the tube or tubes. The tube or tubes may be arranged vertically so that the second fluid rises through the tube or tubes. An outlet port may be provided at the top of the tube or tubes to remove the second fluid. The second fluid may be recirculated through the system via inlet and outlet lines as well as a pump and a replaceable reservoir for holding the second fluid. Where there is an array of tubes, a single inlet and outlet line may be sued for each tube. | 08-28-2014 |
| 20140256028 | SEMICONDUCTOR MICRO-ANALYSIS CHIP AND MANUFACTURING METHOD THEREOF - According to one embodiment, a semiconductor micro-analysis chip for detecting fine particles in sample liquid includes a semiconductor substrate, a first flow channel that is formed in the semiconductor substrate and into which the sample liquid is introduced, and a plurality of columnar structures fully arranged in the first flow channel at regulation distance. | 09-11-2014 |
| 20140273183 | SUBSTRATE DETECTION DEVICE AND BIOFUEL CELL WITH SUBSTRATE DETECTION FUNCTION - There is provided a substrate detection device including a sensor unit configured to extract electrons by oxidizing a substrate, the substrate being a test target, a capacitor connected in series to the sensor unit, and a circuit configured to measure a voltage across terminals of the capacitor. The substrate detection device determines a concentration of the substrate based on the voltage across the terminals of the capacitor. | 09-18-2014 |
| 20140302594 | Cell Culture Assay - The present invention relates to a cell culture assay. The present invention comprises: a substrate; a scaffold channel which is formed along the centre inside the substrate, and of which at least one is disposed continuously, and inside which a scaffold flows; and a microfluidic channel or channels which is/are respectively formed on one side or on both sides of the scaffold channel, and inside which cells flow, and, here, a leak-preventing part for preventing the scaffold from leaking into the microfluidic channel(s) is formed in at least one of the ceiling surface and the floor surface of a boundary part of the scaffold channel and the microfluidic channel(s). | 10-09-2014 |
| 20140377851 | Analysis device - A reagent including a combination of a polyanionic compound and a bivalent cationic compound contains one substance selected from the group consisting of succinic acid, gluconic acid, alanine, glycine, valine, histidine, maltitol, and mannitol or at least one compound of the substance. A dry state of the reagent and deliquescence can be improved. | 12-25-2014 |
| 20150017712 | MASS SPECTROMETRY ANALYSIS OF MICROORGANISMS IN SAMPLES - The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples. | 01-15-2015 |
| 20150024473 | Device and Method for Performing Blood Thromboelastographic Assays by Magnetic Sensing - A magnetic sensor elastometry device (MSED) and a method to perform the whole blood thromboelastography assay. It contains key components, including sample cuvette, detecting head, rotating disc, optical motion detector, and etc; and measures viscoelasticity of whole blood samples. The device optically monitors the physical motion of the magnetically driven rotating disc immersed in the blood sample. The thromboelastograph is recorded by the optical motion detector reading high pulse counts through a gated time window passing through the rotating disc. The device also includes a microcontroller and its embedded firmware to perform the functions of driving the rotating magnetic disc, generating high-frequency pulses, controlling the data pulse time window, as well as handling the user's interface, data analysis, and maintaining communication with an external computer. | 01-22-2015 |
| 20150056686 | GAS-BORNE PATHOGEN SENSOR APPARATUSES AND METHODS THEREOF - A gas-borne pathogen sensor apparatus includes a chamber in a housing having a gas inlet, a gas outlet, and a collection area with a fluid exit port, a liquid misting device, and a sensor element. The liquid misting device is coupled to the chamber and is positioned to spray fluid into the chamber in the housing. The sensor element is positioned in the chamber in the housing and has one or more probes designed to mate with any of one or more targets in a gas supplied to the chamber in the housing through the gas inlet. | 02-26-2015 |
| 20150072402 | BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode | 03-12-2015 |
| 20150087049 | Research Photobioreactor - The invention relates to a research photobioreactor for growth at extremely high cell densities in axenic cultures of cyanobacteria and microalgae exposed to a high light intensity. A hydrophobic gas-permeable first membrane situated at the bottom of the reaction chamber serves for the entry of CO | 03-26-2015 |
| 20150093814 | SYSTEM, AN APPARATUS AND A COMPUTER PROGRAM PRODUCT FOR OBTAINING AN INFORMATION RELATED TO EOSINOPHILIC AIRWAY INFLAMMATION - The present invention provides a system adapted to obtain an information related to eosinophilic airway inflammation. The system comprises a processor and a memory which is under control of said processor. The memory comprises software instructions adapted to enable the computer system to perform operations comprising: receiving an information related to an amount of at least one marker selected from the group consisting of CXCL9 and CCL27 in a blood sample of a subject; and obtaining an information related to eosinophilic airway inflammation in the subject based on the measured amount. | 04-02-2015 |
| 20150118737 | CELL CULTURE DEVICE - There is provided a cell culture device including: a drug storing chamber; a cell culture chamber connected to the drug storing chamber and disposed in a position higher than that of the drug storing chamber; a pump unit circulating a drug from the drug storing chamber to the cell culture chamber; and an opening and closing unit closing an opened part of the drug storing chamber so that the drug storing chamber is isolated from ambient atmosphere. | 04-30-2015 |
| 20150307829 | MOBILE FACILITY FOR PREPARING AND DISTRIBUTING CELL-BASED MEDICINAL PRODUCTS - Example methods, apparatus and system are disclosed relating to a facility for formulating Cell-Based Medicinal Products (CBMPs) in a site where the facility is moved and CBMP formulations are administered. An example facility includes a unitary structure that is assembled together with a vehicle and that houses the working areas and equipment allowing operators to store, count, test, sample, formulate, and/or package CBMPs according to Good Manufacturing Practices. The teachings of the present disclosure relate to a method of providing formulations of a Cell-Based Medicinal Product in sites where the formulations are administered to patients, and from where the facility may be quickly relocated. | 10-29-2015 |
| 20150316528 | SINGLE-USE BIOREACTOR SENSOR ARCHITECTURE - A sensor assembly includes a first sensor and a second sensor. An enclosure is operably coupled to each of the first and second sensors and contains memory that stores compensation data for each of the first and second sensors. A connector is operably coupled to the first and second sensors. A bioreaction sensing assembly as well as a method of manufacturing the bioreaction sensing assembly is also provided. | 11-05-2015 |
| 20150328637 | THERMAL ACTIVATED MICROFLUIDIC SWITCHING - A microfluidic chip assembly having a plurality of microfluidic flow channels is provided. Each channel has a switching region. The microfluidic chip may further include at least one bubble jet actuator configured to generate a pressure pulse in the switching regions of the channels to selectively deflect particles in the flow. The bubble jet actuator may be configured as a blind chamber, as an operative non-through flow chamber and/or as a self-replenishment chamber. The bubble jet actuator may include a trapped air bubble. The bubble jet actuator may include a plurality of heating elements individually controlled for pre-nucleation warmup and/or for triggering vapor bubble nucleation. | 11-19-2015 |
| 20150346125 | ELECTRICAL CHARACTERISTIC MEASURING DEVICE - There is provided an electrical characteristic measuring device including a rotating mechanism that rotates a sample container to be filled with blood to be measured, to any angle, and a measurement unit that applies a voltage between a pair of electrodes installed in the sample container, and chronologically measures electrical characteristics of the blood. | 12-03-2015 |
| 20150362501 | BIOSENSOR AND PROCESS FOR PRODUCING SAME - The present invention provides a biosensor capable of measuring various blood components, in particular, the concentration of blood glucose with high accuracy even when a hematocrit level varies. The above-described object was achieved by a biosensor, which is a biosensor | 12-17-2015 |
| 20160011202 | ANALYTE-TESTING INSTRUMENTS | 01-14-2016 |
| 20160017268 | DEVICE AND METHODS COMPRISING MICROELECTRODE ARRAYS FOR ELECTROCONDUCTIVE CELLS - The present invention relates to the devices and method comprising microelectrode arrays for the differentiation, maturation and functional analysis of electroconductive cells, including muscle cells (including, but not limited to, cardiomyocytes, skeletal muscle myocytes and smooth muscle myocytes) and neuronal cells. The microelectrode present on the arrays can be used to stimulate and record from cells cultured on the substrate. In some embodiments, the substrate has a substantially smooth surface, and in other embodiments the substrate is nanotextured, including an array of substantially parallel grooves and ridges of nanometer-micrometer widths. | 01-21-2016 |
| 20160017269 | BIOREACTOR AND SENSING SYSTEM THEREFOR - The present invention relates to a measurement probe system ( | 01-21-2016 |
| 20160018391 | MICROORGANISM DETECTION SENSOR, METHOD FOR MANUFACTURING SAME, AND POLYMER LAYER - The present invention is a sensor for detecting a microorganism, which is provided with a detection unit equipped with a detection electrode and a polymer layer, wherein the polymer layer is arranged on the detection electrode and is provided with a template having a three-dimensional structure complementary to a three-dimensional structure of a microorganism to be detected. The sensor detects a microorganism on the basis of the captured state of the microorganism onto the template. The polymer layer is formed by a manufacturing method including a polymerization step of polymerizing a monomer in the presence of the microorganism to be detected to form a polymer layer having the microorganism incorporated therein on the detection electrode, and a disruption step of bringing at least a part of the microorganism incorporated in the polymer layer into contact with a solution containing a lytic enzyme to disrupt the microorganism. | 01-21-2016 |
| 20160018393 | TRANSMISSION-LINE-COUPLED MICROFLUIDIC-CHIP TECHNOLOGY FOR ELECTROMAGNETIC SENSING OF BIOMOLECULES AND BIOPARTICLES - A coplanar waveguide transmission line for use in detecting biomolecules and bioparticles is provided that includes a signal conductor disposed on a top surface of the dielectric substrate, a ground conductor disposed on the top surface of the dielectric substrate on each side of the signal conductor, a continuous gap defined between the signal conductor and each of the ground conductors, micro-channels disposed below a top surface of the dielectric substrate, and reservoirs disposed below the top surface of the substrate. | 01-21-2016 |
| 20160045916 | MICROCHIP AND PARTICULATE ANALYZING DEVICE - A microchip is provided, which includes a substrate including a fluid channel structure. The fluid channel structure includes a first fluid introduction channel and a second fluid introduction channel configured to meet so as to allow merging of a first fluid introduced from the first fluid introduction channel and a second fluid introduced from the second fluid introduction channel. A tapered portion is configured to be positioned after merging the first fluid and the second fluid so as to suppress a spiral flow field generated after the merging. | 02-18-2016 |
| 20160051983 | EQUAL-LIQUID-LEVEL RESERVOIR AND A MICROFLUIDIC BIOCHIP - A microfluidic biochip includes an equal-liquid-level reservoir disposed on a cover. The equal-liquid-level reservoir includes some tanks that have a substantially same liquid level. Each tank has an opening on a bottom surface, each opening communicating with a corresponding microfluidic channel. | 02-25-2016 |
| 20160060677 | DEVICE FOR THE MICROBIOLOGICAL DETERMINATION AND ANALYSIS OF A PREPARED LIQUID SAMPLE - The device comprises a microbiologically interactive platform within a liquid-based environment. The platform is positioned by a vertical positioning pin rising centrally from the floor of the device with a floating ball within the device that angles the platform in a specific manner that creates a multiplicity of environments within the device. While the device remains dry, there are no significant microbiological interactions. When a suitably prepared liquid sample is added then there are interactions that allow the determinative analysis of any generated microbiologically generated reactions and responses. These activities are generated primarily from the positioning of the microbiologically interactive platform wherein the platform is formed into an angled profile positioned by the floating ball and the base of the vertical extension pillar. When so positioned, both oxidative and reductive environments are created. Oxidative conditions dominate the platform on the upper side which is directly under the floating ball and where the extension remains exposed. Reductive conditions dominate the lower side of the platform. | 03-03-2016 |
| 20160091455 | CARTRIDGE DEVICE IDENTIFICATION FOR COAGULATION ASSAYS IN FLUID SAMPLES - The present invention relates to analytical testing devices comprising a resistor for cartridge device identification and methods for assaying coagulation in a fluid sample based on the cartridge device identification, and in particular, to performing coagulation assays using a resistor for cartridge device identification in a point of care test cartridge. For example, the present invention may be directed to a chip including an analyte electrode connected to a first connection pin, a reference electrode connected to a second connection pin, and a resistor connected to the second connection pin and a third connection pin. | 03-31-2016 |
| 20160091508 | MICROFABRICATED DEVICE WITH MICRO-ENVIRONMENT SENSORS FOR ASSAYING COAGULATION IN FLUID SAMPLES - The present invention relates to sample analysis cartridges comprising micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using micro-environment sensors in a point of care sample analysis cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample, and a conduit fluidically connected to the inlet chamber and configured to receive the biological sample from the inlet chamber. The conduit may include a micro-environment prothrombin time (PT) sensor, and a micro-environment activated partial thromboplastin time (aPTT) sensor. | 03-31-2016 |
| 20160091517 | Blood Testing System and Method - Some embodiments of a blood coagulation testing system include an analyzer console device and a single-use cartridge component configured to releasably install into the console device. In some embodiments, the blood coagulation testing system can operate as an automated thromboelastometry system that is particularly useful, for example, at a point-of-care site. | 03-31-2016 |
| 20160120451 | Cartridge - A cartridge for insertion into a meter comprises: a plurality of cartridge brackets disposed on an inner wall of the cartridge; a spindle mounted so as to be rotatable within the cartridge and movable longitudinally in first and second directions within the cartridge; and a plurality of testing members each arranged to be supported temporarily by at least one of the plurality of cartridge brackets, each of the testing members including a hole through which the spindle is located, the spindle having a plurality of spindle brackets disposed on an outer surface thereof, each spindle bracket being movable between first and second positions wherein in the first position the spindle bracket's distal end is at a first distance radially from the longitudinal axis of the spindle and wherein in the second position the spindle bracket's distal end is at a greater distance radially from the longitudinal axis of the spindle, and wherein when a given one of the spindle brackets is in the second position its distal end is located against a surface of one of the testing members so as to prevent movement of the testing member in the second longitudinal direction relative to the spindle. When the spindle advances in the second longitudinal direction relative to the cartridge, the spindle brackets are configured to move from the second to the first position so as to allow the spindle brackets to move past the testing members in the second longitudinal direction relative to the testing members, the spindle brackets being configured to return to the second position after moving past the testing members such that each spindle bracket is located against a surface of a different one of the testing members to the testing member against which it was originally located and such that the spindle brackets communicate force from the spindle to the testing members in the first longitudinal direction to move the testing members in the first longitudinal direction as the spindle is moved in the first longitudinal direction. | 05-05-2016 |
| 20160130543 | Modular Microtube Network for Vascularized Organ-On-A-Chip Models - A perfusable, microtube-based flow system for microdevice models of human tissues and organs includes a microfluidic chip with a network of microtubes passing through at least one common chamber space suitable to hold cells of an appropriate organ and/or a biocompatible support matrix. The microtube model network can be used to create model tissues and organs for study and research. | 05-12-2016 |
| 20160137964 | CLAMPING INSERT FOR CELL CULTURE - A clamping insert for cell culture having a lower support with a hollow member engagable in a well of a microplate, the hollow member being open at both ends and including a support surface at one end, and first tightening elements. The clamping insert further having an inner holder sized to be fitted inside the hollow member, and second tightening elements arranged to cooperate with the first tightening elements of the hollow member to tighten reversibly between the inner holder and the support surface of the lower support a porous substrate. The inner holder further including an open channel keeping free the porous substrate. Retaining elements intended to cooperate with the well of the microplate are provided to allow the clamping insert to be suspended in the well, and sealing elements are provided to hermetically seal the contact area between the clamping insert and the porous substrate. | 05-19-2016 |
| 20160139110 | FLUID CHANNEL SYSTEM FOR EXAMINING CELLS - A fluid channel system for examining cells may comprise a chamber filled with at least one photopolymerized hydrogel and/or one polymerized photodepolymerizable hydrogel to at least 90% capacity. The chamber may open exclusively towards at least one fluid channel via at least two openings. The at least one fluid channel and the chamber may each be in the form of a hollow space in a substrate, and each fluid channel may have two openings to the outside. In an embodiment, the system may comprise a hollow space in a substrate with at least one photopolymerized hydrogel and/or one polymerized photodepolymerizable hydrogel may be arranged and structured such that at least one fluid channel and a coherent hydrogel structure are formed. The hydrogel structure may adjoin the at least one fluid channel at two separate surface areas and connect to the outside exclusively via the at least one fluid channel. | 05-19-2016 |
| 20160139116 | IN VITRO CAPTURE AND ANALYSIS OF CIRCULATING TUMOR CELLS - This invention provides methods and compositions for capturing circulating tumor cells (CTCs) as well as various divergent CTC phenotypes using seprase-specific affinity reagents. Methods of analyzing CTCs and assessing their metastatic potential in vivo and in vitro are also disclosed. | 05-19-2016 |
| 20160146748 | RADIO FREQUENCY BIO-SENSOR - A radio frequency (RF) bio-sensor responsive to an analyte of interest comprising an antenna (inductor) integral with a bio-based capacitor, wherein the sensor changes resonant frequency in the presence of the analyte by biologically mediated changes to the capacitor structure and/or materials. The RF biosensor can be interrogated with a vector network analyzer to detect the resonant frequency shift. | 05-26-2016 |
| 20160160170 | OBSERVATION IMAGE CAPTURING AND EVALUATION DEVICE, METHOD, AND PROGRAM - An observation image capturing and evaluation device includes an imaging unit that captures an image of a cell and acquires an observation image, an evaluation unit that evaluates the observation image, and a maturity information acquisition unit that acquires information related to the maturity of the cell. The imaging unit changes a method for capturing the observation image on the basis of the information related to the maturity. | 06-09-2016 |
| 20160161467 | AUTOMATED PLATELET FUNCTION ANALYZER AND ITS ANALYTICAL METHODS - An automated platelet function analyzer includes a sampling vessel, a preparation vessel, an analysis vessel, a sampling needle, an analysis solution syringe, a detergent syringe, and blood mixing devices. The sampling vessel is placed in a sample holder, which vacillates left and right. A method for platelet analysis is also disclosed. | 06-09-2016 |
| 20160172775 | INTERCONNECT DEVICE AND MODULE USING SAME | 06-16-2016 |
| 20160175834 | DROPLET FORMING APPARATUS | 06-23-2016 |
| 20160254131 | MASS SPECTROMETRY ANALYSIS OF MICROORGANISMS IN SAMPLES | 09-01-2016 |
| 20160377577 | PORTABLE HEMOSTASIS ANALYZER - Provided are devices, systems and methods for the use of a portable unit for the evaluation of hemostasis. For example, a portable system for determining a plurality of hemostatic parameters may be included. The system includes a blood sample receptacle, an analyzer and a housing. The blood sample receptacle is configured to hold at least one blood sample. The analyzer is configured to determine at least two hemostatic parameters of the at least one blood sample. The housing is configured to operably couple the blood sample receptacle and the analyzer. The housing is portable and may, for example, have a thickness of 17.5 cm or smaller. | 12-29-2016 |
| 20190142322 | METHODS OF PERSONALIZED MICROFILTRATION TO DETECT CELLS FROM BLOOD | 05-16-2019 |
