| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 435201000 | Acting on alpha-1, 4-glucosidic bond, (e.g., hyaluronidase, invertase, amylase, etc. (some 3.2.1)) | 88 |
| 20080213862 | POLYPEPTIDES HAVING ALPHA-AMYLASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME - The present invention relates to polypeptides having alpha-amylase activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to a polypeptide having carbohydrate-binding affinity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides. | 09-04-2008 |
| 20080254526 | Mutated Xylanase Gene with a Broad PH Range of Reaction and Site-Specific Mutagenesis Method Thereof - A mutated xylanase gene with a broad pH range of reaction includes a forty-first amino acid or a twenty-first amino acid generated from transforming asparagine to aspartic acid so as to form the mutated xylanase gene. A site-specific mutagenesis method includes the step of: mutating the forty-first amino acid or the twenty-first amino acid of the xylanase gene by transforming asparagine to aspartic acid so as to form the mutated xylanase gene. | 10-16-2008 |
| 20080299640 | Acid alpha-glucosidase and fragments thereof - Targeted acid alpha-glucosidase therapeutics that localize to the lysosome are provided. The targeted therapeutics include a therapeutic agent, GAA, and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided. | 12-04-2008 |
| 20090137022 | Extracting and purifying beta 1,4-xylanase - The invention relates to extracting and purifying an enzyme from a cell, particularly, but not exclusively, to extracting and purifying a β1,4-xylanase. | 05-28-2009 |
| 20090263881 | Alpha-Amylase Mutants - The invention relates to a variant of a parent Termamyl-like α-amylase, which exhibits an alteration in at least one of the following properties relative to said parent α-amylase: i) improved pH stability at a pH from 8 to 10.5; and/or ii) improved Ca | 10-22-2009 |
| 20090280553 | METHOD FOR DESIGNING MUTATED ENZYME, METHOD FOR PREPARING THE SAME, AND MUTATED ENZYME - It is intended to provide a novel method for improving an enzyme hydrolyzing an a-1,6-glycosidic linkage. A mutated enzyme is designed by specifying one or more amino acids selected from the group shown below in an amino acid sequence of an enzyme (an enzyme to be mutated) that hydrolyzes an a-1,6-glycosidic linkage, that is, the group consisting of an amino acid corresponding to an amino acid at the 292 position, an amino acid corresponding to an amino acid at the 371 position, an amino acid corresponding to an amino acid at the 406 position, an amino acid corresponding to an amino acid at the 407 position, an amino acid corresponding to an amino acid at the 437 position, an amino acid corresponding to an amino acid at the 465 position, an amino acid corresponding to an amino acid at the 475 position, an amino acid corresponding to an amino acid at the 476 position; an amino acid corresponding to an amino acid at the 525 position, an amino acid corresponding to an amino acid at the 526 position, an amino acid corresponding to an amino acid at the 580 position and an amino acid corresponding to an amino acid at the 582 position of the amino acid represented by in SEQ ID NO: 2 (step (1)) and constructing an amino acid sequence in which the amino acid(s) specified in the step (1) is/are substituted with another amino acid or deleted based on the amino acid sequence of the enzyme to be mutated (step (2)). | 11-12-2009 |
| 20100159563 | Preparation and use of biofilm-degrading, multiple-specificity, hydrolytic enzyme mixtures - The present invention relates to isolated structures containing degradative enzymes produced from a marine organism. The enzymes produced are based on the carbon source upon which the marine organism is growing. The enzymes are found in structures that can be isolated such that the degradative enzymes are easily harvested. | 06-24-2010 |
| 20100209995 | Amylases, Nucleic Acids Encoding Them and Methods for Making and Using Them - In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. In one aspect, the polypeptides of the invention can be used as amylases, for example, alpha amylases, to catalyze the hydrolysis of starch into sugars. | 08-19-2010 |
| 20100233783 | NOVEL METHOD FOR PROTEIN PURIFICATION - Process for purifying a recombinant protein including one or a few procedural steps only. The process combines the step of lysis of the host cell, with the purification of the protein of interest, allowing for a rapid and much more efficient process of purification. The conditions used during the purification process are those of a high temperature and a low pH, allowing for thermostable and acid-resistant recombinant proteins to be isolated from a suspension. The invention also relates to purifying recombinant proteins which are fusion proteins, wherein one part of the protein may be selected from an enamel matrix protein, such as amelogenin. | 09-16-2010 |
| 20110053247 | LARGE-SCALE PRODUCTION OF SOLUBLE HYALURONIDASE - Provided are methods for preparing large-scale preparations of soluble hyaluronidases. The methods employ cells that contain a plurality of active copies of nucleic acid encoding the soluble hyaluronidase and a plurality of feedings and temperature changes, whereby the encoded soluble hyaluronidase is secreted into the cell culture medium. | 03-03-2011 |
| 20110076740 | Amylases, Nucleic Acids Encoding Them and Methods for Making and Using Them - In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used as amylases to catalyze the hydrolysis of starch into sugars. | 03-31-2011 |
| 20110136205 | Alpha-amylase variants with altered properties - The present invention relates to variants (mutants) of polypeptides, in particular Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to said parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency, specific activity, in particular laundry and dish-wash applications. | 06-09-2011 |
| 20110136206 | Alpha-amylase variant with altered properties - The present invention relates to variants (mutants) of parent Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits altered properties relative to the parent alpha-amylase. | 06-09-2011 |
| 20110143419 | Utilization of Pharmacological Chaperones to Improve Manufacturing and Purification of Biologics - The present invention provides methods for improving the production of recombinant proteins through the use of pharmacological chaperones for the recombinant proteins. As exemplified by the present invention, the binding of a pharmacological chaperone to a recombinant protein expressed by a cell can stabilize the protein and increase export of the protein out of the cell's endoplasmic reticulum, and increase secretion of the protein by the cell. | 06-16-2011 |
| 20110195480 | PRODUCTION OF HEMAGGLUTININ-NEURAMINIDASE PROTEIN IN MICROALGAE - The present invention is directed to recombinant microalgal cells and their use in production of heterologous hemagglutinin-neuraminidase (HN) polypeptides, as well as compositions and uses thereof. | 08-11-2011 |
| 20110195481 | Variants And Compositions Comprising Variants With High Stability In Presence Of A Chelating Agent - The present invention relates to variants of an alpha-amylase having improved stability to chelating agents relative to its parent enzyme, compositions comprising the variants, nucleic acids encoding the variants, methods of producing the variants, and methods for using the variants. | 08-11-2011 |
| 20110287516 | Alpha-Amylase Variants - The invention relates to a variant of a parent Termamyl-like alpha-amylase, comprising mutations in two, three, four, five or six regions/positions. The variants have increased stability at high temperatures (relative to the parent). The invention also relates to a DNA construct comprising a DNA sequence encoding an alpha-amylase variant of the invention, a recombinant expression vector which carries a DNA construct of the invention, a cell which is transformed with a DNA construct of the invention, the use of an alpha-amylase variant of the invention for washing and/or dishwashing, textile desizing, starch liquefaction, a detergent additive comprising an alpha-amylase variant of the invention, a manual or automatic dishwashing detergent composition comprising an alpha-amylase variant of the invention, a method for generating a variant of a parent Termamyl-like alpha-amylase, which variant exhibits increased. | 11-24-2011 |
| 20120171748 | Halomonas Strain WDG195-Related Alpha-Amylases, And Methods Of Use, Thereof - Compositions and methods relating to an alpha-amylase enzyme obtained from | 07-05-2012 |
| 20120196348 | Large-scale production of soluble hyaluronidase - Provided are methods for preparing culture medium that contains soluble hyaluronidases. The methods employ cells that contain a plurality of active copies of nucleic acid encoding the soluble hyaluronidase and a plurality of feedings and temperature changes, whereby the encoded soluble hyaluronidase is secreted into the cell culture medium. | 08-02-2012 |
| 20130273632 | BETA-AMYLASE, GENE CODING THEREFOR AND MANUFACTURING METHOD THEREOF - To provide novel β-amylase derived from a microorganism and a gene thereof. β-amylase derived from | 10-17-2013 |
| 20140370569 | EXPRESSION METHOD - In a microbial fermentation, the aim is to increase the product yield of protein. This is achieved by a method in which an expression construct is introduced into a microorganism of the species | 12-18-2014 |
| 20150079659 | SERUM-FREE MAMMALIAN CELL CULTURE MEDIUM, AND USES THEREOF - The present invention provides a cell culture medium formulation that supports the in vitro cultivation, particularly in suspension, of mammalian cells, particularly epithelial cells and fibroblast cells, and methods for cultivating mammalian cells in suspension in vitro using these media. The media comprise a basal medium and a polyanionic or polyanionic compound, preferably a polysulfonated or polysulfated compound, and more preferably dextran sulfate. The present invention also provides chemically defined, protein-free eukaryotic cell culture media comprising an iron chelate and zinc, which is capable of supporting the growth (and particularly the high-density growth of mammalian cells) in suspension culture, increasing the level of expression of recombinant protein in cultured cells, and/or increasing virus production in cultured cells. | 03-19-2015 |
| 20150140637 | PROCESS FOR THE SEPARATION OF A MIXTURE OF A PROTEIN AND ITS REACTION PRODUCT WITH A POLYALKYLENE GLYCOL - The present invention relates to a process for the separation of a mixture of a protein and its reaction product with a polyalkylene glycol, comprising the steps: a) providing a mixture comprising the protein and the reaction product in a fluid, b) bringing the mixture of step a) into contact with a microporous cellulose acetate membrane with adsorption of the reaction product onto the cellulose acetate membrane, the protein not becoming adsorbed onto the cellulose acetate membrane, c) removal of the protein from the cellulose acetate membrane, and d) desorbing the reaction product from the cellulose acetate membrane, the reaction product being selected from the group comprising the protein which is mono- or polyfunctionalized by the polyalkylene glycol, or mixtures thereof. | 05-21-2015 |
| 20150291945 | CELLULOSE AND/OR HEMICELLULOSES DEGRADING ENZYMES FROM MACROPHOMINA PHASEOLINA AND USES THEREOF - The present invention provides nucleotide sequences of | 10-15-2015 |
| 20150337278 | ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME - The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants. | 11-26-2015 |
| 20150359916 | STABILIZED CHLORINE DIOXIDE FOR CONTAMINATION CONTROL IN ZYMOMONAS FERMENTATION - Though chlorine dioxide is generally used to control bacterial contamination, a method was developed which allows the use of stabilized chlorine dioxide (SCD) for controlling contamination during fermentation that uses the bacteria | 12-17-2015 |
| 20160024511 | YEAST PROMOTERS FOR PROTEIN EXPRESSION - Isolated nucleic acids, expression methods, host cells, expression vectors, and DNA constructs for producing proteins, and proteins produced using the expression methods are disclosed. More specifically, nucleic acids isolated from | 01-28-2016 |
| 20160083703 | POLYPEPTIDES HAVING ALPHA AMYLASE ACTIVITY - The present invention relates to polypeptides having alpha-amylase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. | 03-24-2016 |
| 20160083704 | POLYPEPTIDES HAVING ALPHA AMYLASE ACTIVITY - The present invention relates to polypeptides having alpha-amylaseactivity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. | 03-24-2016 |
| 20160108386 | CELLULOLYTIC ENZYMES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - The invention is directed to polypeptides having any cellulolytic activity, e.g., a cellulase activity, e.g., endoglucanase, cellobiohydrolase, beta-glucosidase, xylanase, mannanse, β-xylosidase, arabinofuranosidase, and/or oligomerase activity, including thermostable and thermotolerant activity, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural, food and feed processing and industrial contexts. The invention also provides compositions or products of manufacture comprising mixtures of enzymes comprising at least one enzyme of this invention. | 04-21-2016 |
| 20160168554 | BACTERIAL HYALURONIDASE AND PROCESS FOR ITS PRODUCTION | 06-16-2016 |
| 435202000 | Alpha-amylase, microbial source | 49 |
| 20080227173 | Polypeptide - The invention describes a PS4 variant polypeptide derivable from a parent polypeptide having amylase activity selected from the group consisting of: (a) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 161, 178, 179, 223, 229, 272, 303, 307, 309 and 334; (b) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 145, 146, 157, 178, 179, 223, 229, 272, 303, 307 and 334; (c) a polypeptide comprising an amino acid mutation at each of positions 33, 34, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; and (d) a polypeptide comprising an amino acid mutation at each of positions 3, 33, 34, 70, 121, 134, 141, 146, 157, 178, 179, 223, 229, 272, 303, 307, 309 and 334; with reference to the position numbering of a | 09-18-2008 |
| 20080274531 | Exo-Specific Amylase Polypeptides, Nucleic Acids Encoding Those Polypeptides And Uses Thereof - This invention relates to amylase polypeptides, and nucleic acids encoding the polypeptides and uses thereof. The amylases of the present invention have been engineered to have more beneficial qualities. Specifically the amylases of the current invention show an altered exospecifity. | 11-06-2008 |
| 20090104681 | Polypeptides Having Alpha-Amylase and Granular Starch Hydrolyzing Activity - The present invention relates to a polypeptide having alpha-amylase activity obtained from a strain of | 04-23-2009 |
| 20090117642 | ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES - Disclosed are compositions comprising variants of a parent | 05-07-2009 |
| 20090155882 | Alpha-Amylase Variants - The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the branching point, and improved substrate specificity and/or improved specific activity relative to the parent alpha-amylase. | 06-18-2009 |
| 20090203107 | Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods - Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from | 08-13-2009 |
| 20090203108 | Method for preparing maltogenic alpha-amylase variants - The inventors have modified the amino acid sequence of a maltogenic alpha-amylase to obtain variants with improved properties, based on the three-dimensional structure of the maltogenic alpha-amylase Novamyl. The variants have altered physicochemical properties., e.g. an altered pH optimum, improved thermostability, increased specific activity, an altered cleavage pattern or an increased ability to reduce retrogradation of starch or staling of bread. | 08-13-2009 |
| 20090203109 | Alpha-Amylase Variants - The invention relates to a variant of a parent Termamyl-like α-amylase, comprising mutations in two, three, four, five or six regions/positions. The variants have increased stability at high temperatures (relative to the parent). The invention also relates to a DNA construct comprising a DNA sequence encoding an α-amylase variant of the invention, a recombinant expression vector which carries a DNA construct of the invention, a cell which is transformed with a DNA construct of the invention, the use of an α-amylase variant of the invention for washing and/or dishwashing, textile desizing, starch liquefaction, a detergent additive comprising an α-amylase variant of the invention, a manual or automatic dishwashing detergent composition comprising an α-amylase variant of the invention, a method for generating a variant of a parent Termamyl-like α-amylase, which variant exhibits increased. | 08-13-2009 |
| 20090239284 | Alkaline Bacillus Amylase - This invention relates to an amylase derived from | 09-24-2009 |
| 20090286302 | Desizing and Scouring Process - The present invention relates to processes for combined desizing and scouring of a sized fabric containing starch or starch derivatives during manufacture of fabric, which process comprises incubating said sized fabric in an aqueous treating solution having a pH in the range between 1 and 7, which aqueous treating solution comprises an acid amylase and at least one other acid enzyme facilitating said other fabric treatment steps. The present invention further relates to compositions used in said processes and the use of said compositions. | 11-19-2009 |
| 20100015686 | Variant Alpha-Amylases from Bacillus Subtilis and Methods of Uses, Thereof - Alpha-amylases from | 01-21-2010 |
| 20110076741 | ALPHA-AMYLASE VARIANTS - The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the branching point, and improved substrate specificity and/or improved specific activity relative to the parent alpha-amylase. | 03-31-2011 |
| 20110159570 | Method for preparing maltogenic alpha-amylase variants - The inventors have modified the amino acid sequence of a maltogenic alpha-amylase to obtain variants with improved properties, based on the three-dimensional structure of the maltogenic alpha-amylase Novamyl. The variants have altered physicochemical properties, e.g. an altered pH optimum, improved thermostability, increased specific activity, an altered cleavage pattern or an increased ability to reduce retrogradation of starch or staling of bread. | 06-30-2011 |
| 20110207201 | ALPHA-AMYLASE MUTANTS - The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to said parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca | 08-25-2011 |
| 20110275136 | AMYLASE VARIANTS - The present invention relates to variants (mutants) of polypeptides, in particular Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to said parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca | 11-10-2011 |
| 20120021489 | MICROBIAL ENZYMES AS DETERGENT ADDITIVES - Provided in part herein are compositions that include isolated microbial enzymes, such as amylases, lipases, and proteases that are useful as detergent additives. Also provided are methods of isolating amylases, lipases, and proteases from microbes, as well as methods of using these enzymes as detergent additives, and for stain removal. | 01-26-2012 |
| 20120142074 | Compositions and Uses for an Alpha-Amylase Polypeptide of Bacillus Species 195 - Disclosed herein are compositions comprising an alpha-amylase enzyme obtained from | 06-07-2012 |
| 20120202265 | METHODS FOR REDUCING BLUE SACCHARIDE - The present disclosure relates to a | 08-09-2012 |
| 20120252095 | Alpha-Amylase Variants - The invention relates to a variant of a parent Termamyl-like alpha-amylase, comprising mutations in two, three, four, five or six regions/positions. The variants have increased stability at high temperatures (relative to the parent). The invention also relates to a DNA construct comprising a DNA sequence encoding an alpha-amylase variant of the invention, a recombinant expression vector which carries a DNA construct of the invention, a cell which is transformed with a DNA construct of the invention, the use of an alpha-amylase variant of the invention for washing and/or dishwashing, textile desizing, starch liquefaction, a detergent additive comprising an alpha-amylase variant of the invention, a manual or automatic dishwashing detergent composition comprising an alpha-amylase variant of the invention, a method for generating a variant of a parent Termamyl-like alpha-amylase, which variant exhibits increased. | 10-04-2012 |
| 20120282672 | Alpha-Amylase Mutants - The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to the parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca | 11-08-2012 |
| 20130149770 | Variant Alpha-Amylases from Bacillus Subtilis and Methods of Uses, Thereof - Alpha-amylases from | 06-13-2013 |
| 20130177964 | AMYLASE FROM NESTERENKONIA AND METHODS OF USE, THEREOF - Compositions and methods relating to an alpha-amylase enzyme obtained from | 07-11-2013 |
| 20140141489 | ALPHA-AMYLASE VARIANTS - The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants. | 05-22-2014 |
| 20140141490 | METHOD FACILITATING REMOVAL OF BIOORGANIC STAINS FROM SURFACES - Protein-polymer composite materials are provided according to embodiments of the present invention that include an admixture of a polymer resin, a surfactant and a non-aqueous organic solvent. An aqueous solution containing bioactive proteins is mixed with the admixture. The emulsion is mixed with a crosslinker to produce a curable composition. The curable composition is cured, thereby producing the protein-polymer composite material that is useful for facilitating removal of bioorganic stains. | 05-22-2014 |
| 20140199751 | Protein Extraction - A method for releasing the content of the periplasmic space of bacterial cells is provided, which comprises incubating the bacterial cells in a solution containing styrene maleic acid copolymer (SMA). Also provided is a method of preparing a substantially pure sample of recombinant polypeptide. The methods find application in the recovery of materials, such as proteins, from bacterial cells. | 07-17-2014 |
| 20140199752 | REDUCTION OF CULTURE VISCOSITY BY MANGANESE ADDITION - A method of producing an enzyme of interest in a fed-batch cultivation comprising: a) cultivating a microorganism in a culture medium conducive to its growth wherein the microorganism produces the enzyme of interest; and b) adding a manganese compound to the culture medium one or more times during the cultivation. | 07-17-2014 |
| 20140242667 | AMYLASE VARIANTS - The present invention relates to variants of a parent α-amylase, which parent α-amylase (i) has an amino acid sequence selected from the amino acid sequences shown in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, and SEQ ID No. 7, respectively; or (ii) displays at least 80% homology with one or more of these amino acid sequences; and/or displays immunological cross-reactivity with an antibody raised against an α-amylase having one of these amino acid sequences; and/or is encoded by a DNA sequence which hybridizes with the same probe as a DNA sequence encoding an α-amylase having one of these amino acid sequences; in which variant:
| 08-28-2014 |
| 20140248685 | Alpha-amylase Mutants - The invention relates to a variant of a parent Termamyl-like α-amylase, which exhibits an alteration in at least one of the following properties relative to said parent α-amylase: i) improved pH stability at a pH from 8 to 10.5; and/or ii) improved Ca | 09-04-2014 |
| 20140322795 | Alpha-Amylase Variants - The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the branching point, and improved substrate specificity and/or improved specific activity relative to the parent alpha-amylase. | 10-30-2014 |
| 20140342431 | Variant Alpha-Amylases and Methods of Use, Thereof - Compositions and methods relating to variant alpha-amylases are described. | 11-20-2014 |
| 20150017701 | HYBRID ALPHA-AMYLASES - Hybrid alpha-amylases are provided that share a conserved 3D structure in whole or in part with a wild-type Termamyl-like α-amylase, e.g., a | 01-15-2015 |
| 20150079660 | METHODS FOR REDUCING BLUE SACCHARIDE - The present disclosure relates to a | 03-19-2015 |
| 20150132823 | Alpha-Amylase Variants - The invention relates to a variant of a parent Termamyl-like alpha-amylase, comprising mutations in two, three, four, five or six regions/positions. The variants have increased stability at high temperatures (relative to the parent). The invention also relates to a DNA construct comprising a DNA sequence encoding an alpha-amylase variant of the invention, a recombinant expression vector which carries a DNA construct of the invention, a cell which is transformed with a DNA construct of the invention, the use of an alpha-amylase variant of the invention for washing and/or dishwashing, textile desizing, starch liquefaction, a detergent additive comprising an alpha-amylase variant of the invention, a manual or automatic dishwashing detergent composition comprising an alpha-amylase variant of the invention, a method for generating a variant of a parent Termamyl-like alpha-amylase, which variant exhibits increased. | 05-14-2015 |
| 20160053243 | ALPHA-AMYLASE VARIANTS - Disclosed alpha-amylase/variant alpha-amylase enzymes, nucleic acids encoding the same, and compositions and methods related to the production and use thereof. The alpha-amylase/variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry or dishwashing, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing. | 02-25-2016 |
| 20160053244 | ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES - The present invention relates to variants (mutants) of polypeptides, in particular Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to said parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency, specific activity, in particular laundry and dish-wash applications. | 02-25-2016 |
| 20160115463 | Codon Modified Amylase From Bacillus Akibai - The present invention relates to an isolated synthetic polynucleotide encoding the mature amylase AX856 from | 04-28-2016 |
| 20160130571 | Alpha-Amylase from Bacillaceae Family Member - Disclosed are compositions and methods relating to an alpha-amylase from a Bacillaceae family member. The compositions and methods are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing. | 05-12-2016 |
| 20160160199 | ALPHA-AMYLASES FROM EXIGUOBACTERIUM, AND METHODS OF USE, THEREOF - Disclosed are compositions and methods relating to alpha-amylase from | 06-09-2016 |
| 20160186102 | ALPHA-AMYLASES FROM EXIGUOBACTERIUM, AND METHODS OF USE, THEREOF - Disclosed are compositions and methods relating to alpha-amylase from a subset of | 06-30-2016 |
| 20160201042 | ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME | 07-14-2016 |
| 435203000 | Fungal source | 9 |
| 20100120119 | METHOD OF PRODUCING LIQUID KOJI - An object of the present invention is to provide a method of producing liquid koji having high enzymatic activity by optimizing composition of liquid medium for the liquid koji. In particular, the present invention provides a method of producing liquid koji having enhanced enzymatic activity, the method comprising culturing white koji molds and/or black koji molds in liquid medium containing a nitrogen source by using the cereal of which surface is entirely or partly covered with husks as culture raw material. | 05-13-2010 |
| 20100136655 | FUNGAL ALPHA-AMYLASE VARIANTS - The inventors have developed a method of altering the amino acid sequence of a fungal alpha-amylase to obtain variants, and they have used the method to construct such variants. The variants may be useful for anti-staling in baked products. Accordingly, the invention provides a method of constructing fungal alpha-amylase variants based on a comparison of three-dimensional (3D) structures of the fungal alpha-amylase and a maltogenic alpha-amylase. One or both models includes a substrate. The invention also provides novel fungal alpha-amylase variants. | 06-03-2010 |
| 20100209996 | Thermostable Alpha-Amylases - The present invention relates to an isolated polynucleotide comprising an open reading frame encoding a polypeptide having alpha-amylase activity, the polypeptide selected from the group consisting of: | 08-19-2010 |
| 20100216213 | Polypeptides Having Glucoamylase Activity and Polynucleotides Encoding Same - The present invention relates to polypeptides having glucoamylase activity and isolated polynucleotides encoding said polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides. The invention also relates to the composition comprising a glucoamylase of the invention as well as the use such compositions for starch conversion processes, brewing, including processes for producing fermentation products or syrups. | 08-26-2010 |
| 20130130353 | Variants of Glycoside Hydrolases - The present invention relates to variants of a parent glycoside hydrolase, comprising a substitution at one or more positions corresponding to positions 21, 94, 157, 205, 206, 247, 337, 350, 373, 383, 438, 455, 467, and 486 of amino acids 1 to 513 of SEQ ID NO: 2, and optionally further comprising a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2 a substitution at one or more positions corresponding to positions 8, 22, 41, 49, 57, 113, 193, 196, 226, 227, 246, 251, 255, 259, 301, 356, 371, 411, and 462 of amino acids 1 to 513 of SEQ ID NO: 2, wherein the variants have glycoside hydrolase activity. The present invention also relates to nucleotide sequences encoding the variant glycoside hydrolases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences. | 05-23-2013 |
| 20140342432 | Fungal Gene Expression Using Insulator DNA Sequences - Described are compositions and methods relating to the expression of genes of interest in fungal cells using insulator DNA sequences. | 11-20-2014 |
| 20150044754 | POLYPEPTIDES HAVING ALPHA-AMYLASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME - Provided are isolated polypeptides having alpha-amylase activity, catalytic domains, carbohydrate binding domains and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding domains. Also provided are nucleic acid constructs, vectors and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding domains. | 02-12-2015 |
| 20150064765 | POLYPEPTIDE EXPRESSION METHOD - A method for the production of a polypeptide of interest in a host cell, which method comprises: a. providing a host cell which harbours a nucleic acid encoding a polypeptide of interest, wherein the polypeptide of interest is modified so that it comprises fewer methionine and/or lysine residues than a reference polypeptide, excluding any initial methionine amino acid located at the N-terminal end of the polypeptide sequence; b. cultivating the host cell under conditions suitable for production of the polypeptide; and, optionally, c. recovering the compound of interest. The invention also relates to a modified polypeptide which comprises fewer methionine and/or lysine residues than a reference polypeptide, excluding any initial methionine amino acid located at the N-terminal end of the polypeptide sequence. | 03-05-2015 |
| 20160060641 | MODIFIED FUNGAL HOST CELLS AND METHOD OF USING SAME - Disclosed are modified filamentous fungal cells in which the selective autophagy system of the filamentous fungal cell has been partially or completely inactivated, methods of making such genetically modified filamentous fungal cells, and methods for producing biological products of interest in such modified filamentous fungal cells. Also disclosed are genetically modified filamentous fungal cells having disrupted or deleted atg11 activity, methods of making such genetically modified filamentous fungal cells, and methods for producing biological products of interest in such modified filamentous fungal cells. | 03-03-2016 |
| 435204000 | Alpha-amylase, plant source (3.2.1.1) | 1 |
| 20140273157 | PROCESS FOR ENHANCING THE AMYLASE INHIBITORY EFFICACY FROM PHASEOLUS VULGARIS EXTRACTS - An improved method of purifying bean extract alpha-amylase material is disclosed. The materials purified by this process provide significantly more amylase inhibition than materials purified by other processes. | 09-18-2014 |
| 435205000 | Glucoamylase (3.2.1.3) | 7 |
| 20110014681 | GLUCOAMYLASE VARIANTS - The present invention relates to glucoamylase variants. In particular, the invention relates to variants in the starch binding domain (SBD) of a glucoamylase. The invention also relates to variants having altered properties (e.g., improved thermostability and/or increased specific activity) as compared to a corresponding parent glucoamylase. The present invention also provides enzyme compositions comprising the variant glucoamylases; DNA constructs comprising polynucleotides encoding the variants; and methods of producing the glucoamylase variants in host cells. | 01-20-2011 |
| 20110020899 | GLUCOAMYLASE VARIANTS WITH ALTERED PROPERTIES - The present invention relates to variant glucoamylases wherein the variant has altered properties (e.g., improved thermostability and/or specific activity) compared to a corresponding parent glucoamylase. The present invention also relates to enzyme compositions comprising a variant glucoamylase (e.g., starch hydrolyzing compositions); DNA constructs comprising polynucleotides encoding the variants and methods of producing the variant glucoamylases in host cells | 01-27-2011 |
| 20120149087 | GLUCOAMYLASE VARIANTS WITH ALTERED PROPERTIES - The present disclosure relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present disclosure provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions and cleaning compositions. The disclosure also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells. | 06-14-2012 |
| 20130122569 | Expression of Granular Starch Hydrolyzing Enzymes in Trichoderma and Process for Producing Glucose from Granular Starch Sustrates - The present invention relates to filamentous fungal host cells and particularly | 05-16-2013 |
| 20130122570 | Glucoamylase Variants - The invention relates to a variant of a parent fungal glucoamylase, which exhibits improved thermal stability and/or increased specific activity using saccharide substrates. | 05-16-2013 |
| 20140087442 | GLUCOAMYLASE VARIANTS - The present invention relates to glucoamylase variants. In particular, the invention relates to variants in the starch binding domain (SBD) of a glucoamylase. The invention also relates to variants having altered properties (e.g., improved thermostability and/or increased specific activity) as compared to a corresponding parent glucoamylase. The present invention also provides enzyme compositions comprising the variant glucoamylases; DNA constructs comprising polynucleotides encoding the variants; and methods of producing the glucoamylase variants in host cells. | 03-27-2014 |
| 20150322394 | SYSTEM AND METHOD OF PRODUCING GLUCOMYLASES AND/OR PROTEASES - The present invention is concerned with a system of production of glucoamylases and/or proteases. The system has a packed bed solid state fermentation bioreactor. The bioreactor is adapted to contain and to operate using organic waste as fermentation substrate. The bioreactor is provided with spray nozzle for controlling moisture content of the fermentation substrate, means for supplying air to pass through packed bed of the fermentation substrate in said bioreactor, means for analyzing gas content in said bioreactor, means for monitoring temperature in said bioreactor, means for controlling temperature of said bioreactor, a port via which a sample in said bioreactor is obtainable, and means for harvesting enzymatic solution from said bioreactor, the enzymatic solution containing the glucoamylases and/or proteases. | 11-12-2015 |
