| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 435126000 |
Containing five-membered hetero ring (e.g., griseofulvin, etc.)
| 63 |
| 435125000 |
Containing six-membered hetero ring (e.g., fluorescein, etc.)
| 48 |
| 435124000 |
Containing a hetero ring of at least seven ring members (e.g., zearalenone, macrocyclic lactones, etc.) | 4 |
| 20090286291 | BORRELIDIN-PRODUCING POLYKETIDE SYNTHASE AND ITS USE - The present invention relates to the biosynthesis of polyketides and derives from the cloning of nucleic acids encoding a polyketide synthase and other associated proteins involved in the synthesis of the polyketide borrelidin. Materials and Methods including enzyme systems, nucleic acids, vectors and cells are provided for the preparation of polyketides including borrelidin and analogues and derivatives thereof. Novel polyketide molecules are also provided. | 11-19-2009 |
| 20100009418 | Increasing NADPH-Dependent Products - A method of increasing cellular NADPH levels by expressing one or more genes that encode an enzyme that causes the production of NADPH. The system is combined with other enzymes that require NADPH, thus improving the overall yield of the desired product. | 01-14-2010 |
| 20150353975 | MICROORGANISMS AND METHODS FOR THE PRODUCTION OF CAPROLACTONE - The invention provides non-naturally occurring microbial organisms containing caprolactone pathways having at least one exogenous nucleic acid encoding a butadiene pathway enzyme expressed in a sufficient amount to produce caprolactone. The invention additionally provides methods of using such microbial organisms to produce caprolactone by culturing a non-naturally occurring microbial organism containing caprolactone pathways as described herein under conditions and for a sufficient period of time to produce caprolactone. | 12-10-2015 |
| 20190144899 | ENZYMATIC CYCLIZATION OF HOMOFARNESYLIC ACID | 05-16-2019 |
| Entries |
| Document | Title | Date |
|---|
| 20080206826 | Method for Producing Single Enantiomer Epoxides by the Adh Reduction of a-Leaving Group-Substituted Ketones and Cyclization - The invention relates to a method for producing single enantiomer epoxides by reducing α-leaving group-substituted ketones with (R)- or (S)-selective alcohol dehydrogenases in the presence of a cofactor and optionally a suitable system for regenerating the oxidised cofactor, to produce the corresponding single enantiomer alcohols and subsequently, by means of cyclisation induced by a base, the corresponding single enantiomer epoxides (EQUATION 1) | 08-28-2008 |
| 20080220485 | ENZYMATIC CONVERSION OF EPOXIDES - The invention relates to a process for converting an epoxide to an alcohol. The process according to the invention is enzymatically catalyzed and highly enantioselective and regiospecific. | 09-11-2008 |
| 20080311633 | Plasmid Vectors For Transformation of Filamentous Fungi - A method for preparing substantially enantiopure 3-hydroxy carboxylic acids or esters of the general formula (III) by reacting racemic oxetan-2-ones of the general formula (I) with compounds R3-OH of the general formula (II) in the presence of a lipase from | 12-18-2008 |
| 20090011477 | Stability of Secondary Metabolite Mass Production Through Synchronized Plant Cell Cultures - This invention is a method of minimizing the variation of cell growth and production through homogeneous cell line development. To be more specific, it is the method of isolating and proliferating single cell clone from the procambium to promote the stability of the plant-derived biologically active substances production by solving the problems of decrease in cell growth and the productivity during the long term culture. | 01-08-2009 |
| 20090317877 | MASS PRODUCTION OF SECONDARY METABOLITE IN PLANT CELL CULTURE BY TREATMENT OF SACCHARIDE MIXTURE IN MEDIUM - The present invention relates to a method of producing secondary metabolites with a high yield using plant cell culture, and a medium for the production of secondary metabolites. More specifically, the method of the present invention is characterized in that the plant cell culture is conducted by adding a saccharide mixture to the culture medium as a carbon source, to increase the productivity of the secondary metabolites. For example, the present invention establishes the method of increasing the productivity of secondary metabolites and shortening the culture time by the use of the mixture of glucose and fructose in the plant cell culture, thereby contributing in producing useful secondary metabolites on an industrial scale using plant cell culture. | 12-24-2009 |
| 20100120102 | ENANTIOSELECTIVE EPOXIDE HYDLROLASE AND METHOD FOR PREPARING AND ENANTIOPURE EPOXIDE USING THE SAME - The present invention relates to enantioselective epoxide hydrolase proteins isolated from marine microorganisms, which has high enantioselectivity to various epoxide substrates, and a method of preparing the epoxides with high enantio-purity by using the epoxide hydrolases. The enantioselective hydrolase protein of the present invention can be applied for the preparation of enantiopure epoxides with high bioactivity at a high yield. | 05-13-2010 |
| 20100136635 | Method of Inducing Chirality to Epoxides Using 2,3:4,6 di-O-isopropylidene-2-keto-L-gulonic Acid Monohydrate - The present invention relates to a recyclable method to prepare chirally pure epoxides directly from olefins using a novel chiral acid 2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid monohydrate as chiral inducer and anhydrous hydrogen peroxide in the form of urea hydrogen peroxide adduct (UHP) as oxidant and lipase enzyme as catalyst. Under the influence of lipase, the chiral acid 2,3:4,6-di-O-isopropylidene-2-keto-L-gulonic acid monohydrate is converted to per-acid in situ by the oxidant urea hydrogen peroxide which in turn transfers oxygen to olefin inducing chirality to the product epoxide. Using this technique, important epoxide building blocks of different industrially important compounds can be prepared with good yield and moderate enantioselectivity. Chiral epoxidation of olefins with environment friendly catalytic system that can be recycled is highly desirable in the context of Green Chemistry for preparation of many industrially important compounds. | 06-03-2010 |
| 20100209978 | GENE-DISRUPTED STRAIN, RECOMBINANT PLASMIDS, TRANSFORMANTS AND PROCESS FOR PRODUCTION OF 3-CARBOXYMUCONOLACTONE - Industrial-scale fermentative production of 3-carboxy-cis,cis-muconic acid from terephthalic acid. Also, a protocatechuate 4,5-ring-cleaving enzyme gene-disrupted strain in which the gene coding for (a) the amino acid sequence set forth in SEQ ID NO: 1 or 3, or (b) the amino acid sequence set forth in SEQ ID NO: 1 or 3 which has a deletion, substitution, addition and/or insertion of one or more amino acids and exhibits protocatechuate 4,5-ring cleavage activity, present in the chromosomal DNA of microbial cells, has been disrupted; recombinant plasmids comprising the Tph gene and protocatechuate 3,4-dioxygenase gene; transformants obtained by introducing the recombinant plasmids into the disrupted strain; and a process for production of 3-carboxy-cis,cis-muconic acid and/or 3-carboxymuconolactone characterized by culturing the transformants in the presence of terephthalic acid. | 08-19-2010 |
| 20110014664 | Fermentation Process for Higher Yield Coefficient of Lipase-Inhibitor with Respect to Consumed Fatty Acid - The invention provides a process for the production of lipase inhibitors via an improvised fermentation process characterized in that a combinatorial feeding of linoleic acid or its esters or salts thereof and an omega-9 fatty acid, preferably oleic acid and/or its derivatives is employed during said process resulting in an improved yield co-efficient, productivity further providing ease of operation. | 01-20-2011 |
| 20110033903 | Isolated population of plant single cells and method of preparing same - This invention is a method of minimizing the variation of cell growth and production through homogeneous cell line development. To be more specific, it is the method of isolating and proliferating single cell clone from cambium to promote the stability of the plant-derived biologically active substances production by solving the problems of decrease in cell growth and the productivity during the long term culture. | 02-10-2011 |
| 20110039312 | Isolated population of plant single cells and method of preparing same - This invention is a method of minimizing the variation of cell growth and production through homogeneous cell line development. To be more specific, it is the method of isolating and proliferating single cell clone from procambium to promote the stability of the plant-derived biologically active substances production by solving the problems of decrease in cell growth and the productivity during the long term culture. | 02-17-2011 |
| 20110086397 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES - This invention provides methods whereby taxol, baccatin III, and other taxol-like compounds, or taxanes, can be produced in very high yield from all known | 04-14-2011 |
| 20110165634 | RENEWABLE CHEMICAL PRODUCTION FROM NOVEL FATTY ACID FEEDSTOCKS - Disclosed herein are methods of manufacturing renewable chemicals through the manufacture of novel triglyceride oils followed by chemical modification of the oils. Methods such as transesterification, hydrogenation, hydrocracking, deoxygenation, isomerization, interesterification, hydroxylation, hydrolysis and saponification are disclosed. Novel oils containing fatty acid chain lengths of C8, C10, C12 or C14 are also disclosed and are useful as feedstocks in the methods of the invention. | 07-07-2011 |
| 20120190086 | KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROUTE TO ALPHA CHLOROALCOHOLS - The present disclosure relates to engineered ketoreductase polypeptides and uses thereof for the preparation of α chloroalcohols from α chloroketones. Also provided are polynucleotides encoding the engineered ketoreductase polypeptides and host cells capable of expressing the engineered ketoreductase polypeptides. | 07-26-2012 |
| 20130017582 | ENHANCED PRODUCTION OF TAXOL AND TAXANES BY CELL CULTURES OF TAXUS SPECIES - This invention provides methods whereby taxol, baccatin III, and other taxol-like compounds, or taxanes, can be produced in very high yield from all known | 01-17-2013 |
| 20130157322 | PROCESS FOR PRODUCING ETHANOL AND ETHYLENE VIA FERMENTATION - A process for converting a substrate such as carbon monoxide to useful chemicals has been developed. The process involves providing a substrate comprising CO to a bioreactor which contains a culture of one or more micro-organisms and anaerobically fermenting the substrate to produce ethanol. The ethanol is next converted to one or more chemical products via the compound ethylene. The source of the CO can be an industrial process such as the ferrous metal products manufacturing. The microorganism can be | 06-20-2013 |
| 20130224808 | PROCESS AND APPARATUS FOR PRODUCING ETHYLENE VIA PREPARATION OF SYNGAS - A process for producing ethylene from a carbonaceous containing feedstock the process comprising the steps of a) reforming the carbonaceous containing feedstock into a first product stream comprising carbon dioxide, carbon monoxide and hydrogen; b) fermenting the first product stream with an acetogenic anaerobic bacteria to produce a second product stream comprising ethanol; c) concentrating ethanol from the second product stream into a third product stream and; d) dehydrating ethanol in the third product stream to produce ethylene. | 08-29-2013 |
| 20140057325 | Microbial Conversion of Glucose to Styrene and Its Derivatives - A method for the in vivo production of styrene from renewable substrates using a recombinant microorganism is disclosed. Additionally, a method for the in vivo production of styrene oxide from renewable substrates using a recombinant microorganism is also disclosed. In both cases, the host cell expresses at least one gene encoding a polypeptide that possesses phenylalanine ammonia lyase activity in addition to at least one gene encoding a polypeptide that possesses trans-cinnamic acid decarboxylase activity. In the case of styrene oxide, the host cell must additionally express at least one gene encoding a polypeptide that possesses styrene monooxygenase activity. | 02-27-2014 |
| 20150050705 | Epoxidation Using Peroxygenase - The invention relates to enzymatic methods for epoxidation of a non-cyclicaliphatic alken, or a terpen. | 02-19-2015 |
| 20150056669 | ACETYL-COA CARBOXYLASES - The present invention provides various combinations of genetic modifications to a transformed host cell that provide increase conversion of carbon to a chemical product. The present invention also provides methods of fermentation and methods of making various chemical products. | 02-26-2015 |
| 20160177353 | BIOLOGICAL PRODUCTION OF ORGANIC COMPOUNDS | 06-23-2016 |
| 20170233355 | EPOXIDATION USING PEROXYGENASE | 08-17-2017 |
