| Entries |
| Document | Title | Date |
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| 20080213806 | Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same - The disclosed technology provides an enriched antibody population, highly specific for an antigen of a surface polysaccharide, from a mycobacterium. In a related embodiment, the antibody is enriched by having been raised in an environment that maintains antigenically active antigen. These antibodies may be used in an immunoreactive environment for detecting the presence of a mycobacterial infection in a sample from a subject. | 09-04-2008 |
| 20080220456 | LUMINESCENCE RESONANCE ENERGY TRANSFER (LRET) ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY - Clostridial toxin substrates comprising a lanthanide donor complex, an acceptor, and a Clostridial toxin recognition sequence including a cleavage site; methods for determining the activity of a Clostridial toxin from a test sample using such Clostridial toxin substrates; cell compositions comprising such Clostridial toxin substrates and a Clostridial toxin receptor; and methods for determining the activity of a Clostridial toxin from a test sample using such cell compositions. | 09-11-2008 |
| 20080220457 | Serum Bactericidal Assay for N. Meningitidis Specific Antisera - The present invention relates to the field of Serum Bactericidal Activity (SBA) assays for Gram negative bacteria, in particular | 09-11-2008 |
| 20080220458 | Antibodies specific to antigens of bartonella henselae and use of these antigens in immunoassays - Disclosed are antibodies that bind to the antigenic proteins GroES, RpIL, GroEL, SodB, UbiG, the ABC transporter, and an expressed antigenic protein of unknown function (the “BepA” protein) of | 09-11-2008 |
| 20080299591 | Identification of Porphyromonas gingivalis virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases - The invention provides compositions and methods for the detection of | 12-04-2008 |
| 20080311596 | Genes of Porphyromonas Gingivalis W83 Involved in Invasion of Human Cells - Compositions and methods are provided for detection and treatment of | 12-18-2008 |
| 20090011442 | TB diagnostics based on mycobacterium tuberculosis excretory secretory antigens and their specific immunoglobulins - The present invention relates to isolation and identification of novel | 01-08-2009 |
| 20090017476 | Multiple Component Nanoparticles for Multiplexed Signaling and Optical Encoding - The present invention provides multiple-luminophore silica nanoparticles for multiplexed signaling in bioanalysis. In specific embodiments, two inorganic luminophores, Tris(2,2′-bipyridyl)osmium(II) bis(hexafluorophosphate) (OsBpy) and Tris(2,2′-bipyridyl)dichlororuthenium(II) hexahydrate (RuBpy), or three organic luminophores 5-Fluorescein isothiocyanate (5-FITC), 5-carboxyrhodamine 6G, succinimidyl ester (5-CR6G, SE), 6-carboxy-X-rhodamine, succinimidyl ester (6-ROX, SE) can be simultaneously entrapped inside silica nanoparticles at controlled ratios, with desirable sizes and required surface functionality. Single-wavelength excitation with multiple emission endows the nanoparticles with optical encoding capability for rapid and high-throughput multiplexed detection. | 01-15-2009 |
| 20090023162 | METHOD FOR THE IDENTIFICATION OF ATYPICAL P-ANCA - The invention relates to a method for the identification of atypical p-ANCA, kits suitable for the same and application of said method to the diagnosis of chronic inflammatory intestinal diseases and autoimmune liver diseases. | 01-22-2009 |
| 20090042222 | Peptides for Detection of Antibody to Anaplasma phagocytophilum - The invention provides compositions and methods for the detection and quantification of | 02-12-2009 |
| 20090061464 | METHODS FOR DETECTING AND/OR QUANTIFYING A CONCENTRATION OF SPECIFIC BACTERIAL MOLECULES USING BACTERIAL BIOSENSORS - A real-time method employing a portable peptide-containing potentiometric biosensor, can directly detect and/or quantify bacterial spores. Two peptides for specific recognition of | 03-05-2009 |
| 20090117596 | Antibody-Sensitized Latex - Antibody-sensitized latex for use in determination of a bacterium belonging to the genus | 05-07-2009 |
| 20090148870 | Rapid Detection of Mycobacterium Tuberculosis and Antimicrobial Drug Resistance - The invention includes methods and kits for rapidly detecting tuberculosis or other mycobacterial infection in a sputum sample inexpensively and within minutes. It includes methods and kits for determining the species or phylogenetic group of mycobacterial infection. It includes methods and kits for determining the drug sensitivity of mycobacteria from a sputum sample inexpensively and within 1-3 days. | 06-11-2009 |
| 20090162875 | Peptide diagnostic agent for lyme disease - The present invention relates, e.g., to an isolated peptide consisting of the sequence MKKDDQIAAAIALRGMA (SEQ ID NO:1) or an active variant thereof, wherein the peptide or active variant can bind specifically to an antibody induced by a causative agent of Lyme disease (a pathogenic | 06-25-2009 |
| 20090215092 | Antibodies for Anthrax - A targeted approach is described for the production of biological recognition elements capable of fast, specific detection of anthrax spores on biosensor surfaces. Single chain antibodies (scFvs) are produced to EA1, a | 08-27-2009 |
| 20090263836 | BOTULINUM TOXIN SCREENING ASSAYS - Methods for detecting BoNT/A activity in a sample, methods for screening molecules able to compete with BoNT/A receptor binding, methods for reducing BoNT/A activity in a human and methods of marketing a neurotoxin capable of selectively binding to a FGFR2, a FGFR3, a SV2, or any combination thereof, to a governmental or regional regulatory authority. | 10-22-2009 |
| 20090269788 | METHOD FOR DETECTING MICROORGANISM - A method for detecting a microorganism in a sample containing or suspected of containing said microorganism, said method comprising: i) contacting said sample with a binding agent for said microorganism, wherein the binding agent is immobilised on a support, and allowing the binding agent to bind microorganism to form an immobilised complex; ii) separating the sample from the immobilised complex; iii) contacting the support with a liquid medium and a reagent which removes which eliminates, inactivates or inhibits a contaminant that may interfere with a microorganism detection assay; and iv) detecting microorganisms retained on the support using said microorganism detection assay. | 10-29-2009 |
| 20090291460 | Assay for transmissible spongiform encephalopathies - Provided is a novel method for detecting Transmissible Spongiform encephalopathies (TSE). The method comprises: selecting a sera sample from a subject to determine whether the subject has transmissible spongiform encephalopathy; and detecting antibodies that immune react with | 11-26-2009 |
| 20090311722 | Truncated recombinant major outer membrane protein antigen (R56) of orientia tsutsugamushi strains Karp, Kato and Gilliam and its use in antibody based detection assays and vaccines - A recombinant, refolded non-fusion polypeptide expressed from a truncated r56 gene of the causative agent of scrub typhus, | 12-17-2009 |
| 20090317838 | DETECTION OF BACTERIAL PEPTIDOGLYCAN-LIKE COMPOUNDS - Innate immunity to bacterial pathogens relies on the detection of bacterial peptidoglycans. Intracellular NOD2 proteins sense peptidoglycans and respond by activating transcription factors. An in vitro assay utilizing a reporter gene under the control of a promoter that contains transcription recognition sequences for the binding of a transcription factor that is activated by NOD2 in cells transfected to express NOD2 or NOD2 and TLR2 can identify bacterial infection or sepsis by detecting bacterial peptidoglycans. | 12-24-2009 |
| 20090317839 | BOTULINUM TOXIN SCREENING ASSAYS - Methods for detecting BoNT/A activity in a sample, methods for screening molecules able to compete with BoNT/A receptor binding, methods for reducing BoNT/A activity in a human and methods of marketing a neurotoxin capable of selectively binding to FGFR3 to a governmental or regional regulatory authority. | 12-24-2009 |
| 20100075346 | FRET PROTEASE ASSAYS FOR CLOSTRIDIAL TOXINS - The present invention provides clostridial toxin substrates useful in assaying for the protease activity of any clostridial toxin, including botulinum toxins of all serotypes as well as tetanus toxins. A clostridial toxin substrate of the invention contains a donor fluorophore; an acceptor having an absorbance spectrum overlapping the emission spectrum of the donor fluorophore; and a clostridial toxin recognition sequence that includes a cleavage site, where the cleavage site intervenes between the donor fluorophore and the acceptor and where, under the appropriate conditions, resonance energy transfer is exhibited between the donor fluorophore and the acceptor. | 03-25-2010 |
| 20100129836 | System for detecting bacteria in blood, blood products, and fluids of tissues - The invention provides methods for screening for the presence of a clinically relevant amount of bacteria in donor blood or a blood product from a donor mammal, particularly blood or a blood product that will be transferred from the donor mammal to a recipient mammal. The method comprises contacting a sample of the donor blood or a blood product with a set of binding agents that comprises binding agents that specifically bind to Gram-negative bacterial antigen and/or binding agents that specifically bind to Gram-positive bacterial antigen, and determining binding of the set of binding agents to the sample, wherein binding indicates the presence of a clinically relevant amount of Gram-positive bacteria and/or Gram-negative bacteria in the donor blood or blood product and no binding indicates the absence of a clinically relevant amount of Gram-positive bacteria and/or Gram-negative bacteria in the donor blood or blood product. | 05-27-2010 |
| 20100129837 | METHODS OF CAPTURING BACTERIAL WHOLE CELLS AND METHODS OF ANALYZING SAMPLES FOR BACTERIA - In certain embodiments, the invention relates to methods of capturing bacterial whole cells that includes the use of two or more antibodies having antigenic specificities for two or more distinct analytes characteristic of the specific bacterium. In certain embodiments, the invention relates to methods of analyzing a sample for a bacterium of interest. In particular, the methods are useful for detecting one or more analytes characteristic of a bacterium of interest, such as components of cell walls that are characteristic of a bacterium, particularly | 05-27-2010 |
| 20100136586 | METHOD FOR THE SURVEILLANCE FOR BIOLOGICAL, CHEMICAL AND RADIOLOGICAL AGENTS - Provided is a method of surveillance for hazardous materials, e.g., chemical, biological and radiological agents. The method comprises assaying a sample derived from materials collected from a sample domain for the presence of a chemical, biological, or radiological agent. The sample domain comprises at least one collection point from which the materials are collected in a pre-existing operation unrelated to surveillance. | 06-03-2010 |
| 20100151502 | FUNCTIONAL EXPRESSION OF TRIACYLGYLCEROL LIPASES - The present invention relates to nucleic acids that code for triacylglycerol lipases, vectors comprising said nucleic acids, host cells comprising said nucleic acids or vectors, methods for the expression of triacylglycerol lipases in prokaryotes, methods for the detection and for the production of triacylglycerol lipases, triacylglycerol lipases obtainable thereby, and the use of triacylglycerol lipase-encoding nucleic acids, vectors and recombinant host cells for said methods. | 06-17-2010 |
| 20100159485 | DETECTION OF MYCOBACTERIUM TUBERCULOSIS - The present technology relates generally to the use of an Rv1168c polypeptide, or fragments thereof, or Rv1168c polypeptide binding agent for detecting or diagnosing exposure to | 06-24-2010 |
| 20100184103 | METHODS OF USE OF SOLID SUPPORT MATERIAL FOR BINDING BIOMOLECULES - Functionalized solid support material with biomolecule-binding groups and uses thereof, wherein the biomolecule-binding groups include a plurality of aromatic groups, an amine group which bonds to a biomolecule through an aldehyde group, a hydrazine group which bonds to a biomolecule through an aldehyde group, or an alpha,beta-ethylenically or acetylenically unsaturated group with an electron withdrawing group. | 07-22-2010 |
| 20100216172 | FLOW-BASED ENHANCEMENT OF SPECIFICITY FOR LABEL-FREE BIOCHEMICAL ASSAYS - A label-free biochemical assay, in which label-free interrogation of a target-receptor layer is performed while the target-receptor layer is subjected to a relatively strong flow of an analyte-containing fluid. The volumetric flow rate for the assay is selected based on calibration data corresponding to the target substance, which advantageously results in fewer and/or smaller false-positive signals corresponding to non-target substances compared to those produced with the fluid being stationary. In various embodiments, the label-free interrogation method can be electro-mechanical and/or optical. | 08-26-2010 |
| 20100221758 | Sensors for Measuring Contaminants - The present invention provides biosensors and methods of use for detecting the presence or absence of mycoplasma contamination through the detection of hydrolytic enzymes that are conserved among | 09-02-2010 |
| 20100240075 | COMPLEMENT FACTOR H-BASED ASSAYS FOR SERUM BACTERICIDAL ACTIVITY AGAINST NEISSERIA MENINGITIDIS - Assays for detection of bactericidal anti-Neisserial antibodies using a factor H polypeptide having a human amino acid sequence that mediates binding to Neisserial factor H binding protein (fHBp) are provided, as well as non-human animal models of Neisserial infection. | 09-23-2010 |
| 20100248267 | METHOD FOR MEASUREMENT OF CONCENTRATION OF ANTIGEN - The object of the present invention is to provide a detection method that can detect an antigen even if the target antigen has a low molecular weight in a simpler, more efficient, and more stable manner and with higher sensitivity. The detection of the antigen is carried out by using a fusion protein comprising a polypeptide containing a V | 09-30-2010 |
| 20100255511 | IMMUNOLOGICAL TESTS FOR THE PRESENCE OF BACTERIA WHICH MAKE USE OF ANTIBODIES OBTAINED USING A SPECIFIC METHOD - The use of a bacterial antigen obtained from bacterial cells in the production of antibodies for immunological assays for detecting bacterial cells. | 10-07-2010 |
| 20100285506 | IMMUNODETECTION ASSAY FOR MYCOBACTERIUM TUBERCULOSIS COMPLEX - The present invention provides a method for specifically detecting a | 11-11-2010 |
| 20100291596 | SCREENING METHOD FOR AGENTS SUITABLE FOR THERAPY OF ALZHEIMER'S DISEASE - Described is a method of screening for therapeutic agents for the prophylaxis and therapy of Alzheimer's disease (AD), wherein agents that (i) do not interfere with the biological activity of gamma-secretase, (ii) do not exhibit cytotoxicity, (iii) lead to reduced amounts of Abeta42 and (iv) are capable of binding to an APP-GxxxG motif thereby weakening or inhibiting dimerization of the APP transmembrane sequence are suitable for prophylaxis or treatment of AD. | 11-18-2010 |
| 20100311088 | Recombinant antigens for diagnosis and prevention of murine typhus - The invention relates to the construction of recombinant, immunodominant | 12-09-2010 |
| 20100317037 | Detection of Mycobacterium Tuberculosis Bacilli - A screening test for | 12-16-2010 |
| 20110020845 | METHOD FOR THE DETECTION AND IDENTIFICATION OF A VARIANT C. DIFFICILE STRAIN IN A SAMPLE - The method for detecting and identifying a variant | 01-27-2011 |
| 20110039280 | HYBRID MICROFLUIDIC SPR AND MOLECULAR IMAGING DEVICE - A hybrid microfluidic biochip designed to perform multiplexed detection of singled- celled pathogens using a combination of SPR and epi-fluorescence imaging. The device comprises an array of gold spots, each functionalized with a capture biomolecule targeting a specific pathogen. This biosensor array is enclosed by a polydimethylsiloxane (PDMS) microfluidic flow chamber that delivers a magnetically concentrated sample to be tested. The sample is imaged by surface plasmon resonance on the bottom of the biochip, and epi- fluorescence on the top. | 02-17-2011 |
| 20110065132 | Identification of Actinobacillus actinomycetemcomitans Antigens for use in the Diagnosis, Treatment and Monitoring of Periodontal Diseases - Antibodies, polypeptides, and polynucleotides are provided for the detection, prevention, amelioration and treatment of diseases caused by | 03-17-2011 |
| 20110076699 | Hemolysin and its protein fragments in sero-detection of anaplasma phagocytophilum - Disclosed is the cloning, expression and purification of a hemolysin protein and its protein fragments in | 03-31-2011 |
| 20110104721 | Human ABO Blood Group-Binding Lactobacilli - screening methods were carried out using surface plasmon resonance spectrums and human intestinal mucin and blood group antigens as probes. A trial to set selection criteria in the above-mentioned methods of screening for lactobacilli was made to adapt the methods to mass screening, and it was discovered that lactobacilli compatible with ABO blood groups can be screened by setting 100 RU as a criterion for judging bacterial binding under certain conditions. Using 238 | 05-05-2011 |
| 20110117580 | REDUCING LEUKOCYTE INTERFERENCE IN NON-COMPETITIVE IMMUNOASSAYS - The invention is directed to methods and devices for reducing interference from leukocytes in an analyte immunoassay, and in particular in non-competitive immunoassays. In one embodiment, the invention is to a method comprising the steps of (a) amending a biological sample such as a whole blood sample with sacrificial beads; and (b) performing a non-competitive immunoassay on the amended sample to determine the concentration of said analyte in said sample. Preferably, the sample is amended with IgG-coated sacrificial beads. | 05-19-2011 |
| 20110117581 | REDUCING LEUKOCYTE INTERFERENCE IN COMPETITIVE IMMUNOASSAYS - The invention is directed to methods and devices for reducing interference from leukocytes in an competitive analyte immunoassays. In one embodiment, the invention is to a method comprising the steps of (a) amending a biological sample such as a whole blood sample with sacrificial beads opsonized for leukocytes; and (b) performing a competitive immunoassay on the amended sample to determine the concentration of said analyte in said sample. Preferably, the sample is amended with IgG-coated sacrificial beads. | 05-19-2011 |
| 20110171667 | REACTION MEDIUM FOR DETECTING AND/OR IDENTIFYING BACTERIA OF THE LEGIONELLA GENUS - A reaction medium for the culture and/or detection and/or identification of bacteria of the | 07-14-2011 |
| 20110183360 | ANTIBODIES TO CLOSTRIDIUM DIFFICILE SPORES AND USES THEREOF - The present invention provides antibodies that bind to the endospore of the bacterium | 07-28-2011 |
| 20110229913 | Method for Amplification of Signal in Immunochromatographic Assay and Immunochromatographic Kit Using the Method - The present invention relates to a method for amplifying a signal in an immunochro-matographic assay for high-sensitivity detection of an analyte and an immunochromatographic kit using the method, which amplifies a signal by controlling a flow rate by discrimination between the size of a first indicator and the size of a second indicator. According to an aspect of the present invention, a method for amplifying a signal in an im | 09-22-2011 |
| 20110287452 | Test Kit for Detecting Klebsiella Pneumoniae Serotype K1 and Method Using Same - Disclosed are a test kit and method for sensitively and rapidly detecting | 11-24-2011 |
| 20110294143 | METHOD FOR DETECTING ALL HAEMOPHILUS INFLUENZAE - Provided is an immunoassay method whereby all | 12-01-2011 |
| 20110300561 | Method for Identifying Inhibitors of Staphylococcus Aureus - Provided are methods for identifying and/or designing inhibitors of | 12-08-2011 |
| 20120015379 | DIAGNOSIS OF BACILLUS ANTHRACIS INFECTION BASED ON DETECTION OF BACTERIAL SECRETED BIOMARKERS - A novel and rapid diagnostic method for anthrax infection is provided. Three | 01-19-2012 |
| 20130130281 | CYSTEINE PROTEASE Cwp84 (CD2787) AS A DIAGNOSTIC MARKER FOR CLOSTRIDIUM DIFFICILE - Accurate and fast detection of the presence of | 05-23-2013 |
| 20130236915 | METHOD OF INSPECTING PERIODONTAL DISEASE CAUSING BACTERIA USING OUTER MEMBRANE VESICLE AND MEASURING APPLIANCE OF THE SAME - The invention provides a method of inspecting bacteria by using an outer membrane vesicle of the bacteria, which is useful for easily diagnosing a periodontopathic bacteria with high precision. An outer membrane vesicle of bacteria to be detected is previously arranged in a measuring portion of a measuring appliance, a specimen material collected from a test subject is brought into contact with the measuring portion, and an anti-outer membrane vesicle antibody corresponding to the outer membrane vesicle in the specimen material is detected on the basis of an antigen antibody reaction. A measuring appliance for executing the inspecting method of the bacteria is structured such that the outer membrane vesicle of the bacteria to be detected is previously arranged in the measuring portion. | 09-12-2013 |
| 20130273572 | Methods for Diagnosing Lyme Disease - A method for diagnosing Lyme disease status in a mammal is provided. The method entails, in a biological sample obtained or derived from a mammal, determining antibodies to | 10-17-2013 |
| 20140127718 | IDENTIFICATION OF SECRETED PROTEINS AS DETECTION MARKERS FOR CITRUS DISEASE - Secreted proteins as detection markers for insect vector and graft transmitted citrus disease are described. Method and kits for detecting the secreted proteins are provided. | 05-08-2014 |
| 20140186859 | AUTOFOCUS METHOD FOR IMAGING A BIOLOGICAL SAMPLE AND CARTRIDGE FOR USE THEREIN - A method of automatically focusing a microscope on a specimen is carried out by capturing an image from each of a plurality of focal planes in or on said specimen, calculating a focus score for each of said images, selecting the focal plane corresponding to the image having the best focus score, and then repositioning said specimen relative to said microscope so that said microscope is focused on said selected focal plane, the method includes a plurality of exogenous targets in or on said specimen, which aids in focusing in the event particular objects of interest, such as cells/pathogens that may or may not be in the sample, are not present, or are present in low numbers. Automated microscopes and microscope cartridges useful in such methods are also described, along with methods of detecting pathogens in biological samples. | 07-03-2014 |
| 20140242613 | RAPID IDENTIFICATION OF ORGANISMS IN BODILY FLUIDS - There is provided a lateral flow assay that can provide an indication of Gram negative (GN) or Gram positive (GP) infection (or both) within 30 minutes, and desirably in less than 15 minutes. The immediate result would signal the presence of Gram negative bacteria, Gram positive bacteria, both Gram negative and Gram positive bacteria, or no bacteria detected. The detection level would be above a specific bacterial concentration threshold that is clinically significant infection source (e.g. 10̂3 cfu/ml) versus the presence of a colonizing bacteria that is not a part of the active infection. | 08-28-2014 |
| 20140335543 | ANTIBODIES TO CLOSTRIDIUM DIFFICILE SPORES AND USES THEREOF - The present invention provides antibodies that bind to the endospore of the bacterium | 11-13-2014 |
| 20140342376 | Immunoassay for Detecting Antibiotics - The present invention relates to a device and method for detecting analytes in a sample. | 11-20-2014 |
| 20150044697 | OUTER MEMBRANE PROTEIN 18 AS A DIAGNOSTIC MARKER FOR CAMPYLOBACTER - Accurate and fast detection of the presence of | 02-12-2015 |
| 20150044698 | OUTER MEMBRANE PROTEIN 18 AS A DIAGNOSTIC MARKER FOR CAMPYLOBACTER - Accurate and fast detection of the presence of Campylobacter disease is important for the proper treatment of patients with Campylobacter infection. Present tests depend upon culture of viable bacteria and identification by microscopy, which requires care, skill, and two or more days for conclusive results. The current invention improves the ease of use and overcomes the limitations of loss of viability and delay inherent in Campylobacter bacterial culture and provides a more rapid alternative for the identification and diagnosis of Campylobacter and campylobacteriosis. The invention provides a new method of detecting Campylobacter by utilizing an outer membrane protein (OMP 18) to develop antibodies for use in immunoassays of bacterial cultures or human fecal samples. | 02-12-2015 |
| 20150125883 | METHOD OF ISOLATING AND CHARACTERIZING MICROORGANISMS THAT ARE TARGETS OF HOST IMMUNE RESPONSES - The present invention encompasses methods of isolating, identifying, and characterizing microorganisms present in a microbial community occupying a body habitat/surface of a healthy or unhealthy human or animal. More particularly, the invention relates to methods of isolating and identifying viable microorganisms that interact with a host's immune system. | 05-07-2015 |
| 20160053295 | Methods for Antimicrobial Resistance Determination - The present invention relates to methods and systems for determining the antibiotic-resistance status of microorganisms. The invention further provides methods for determining the antibiotic-resistance status of microorganisms in situ within a single system. | 02-25-2016 |
| 20160083458 | ANTI-LIPOARABINOMANNAN ANTIBODY AND IMMUNOASSAY FOR ACID-FAST BACILLARY INFECTION USING THE ANTIBODY - The present invention provides a monoclonal antibody that specifically binds to acid-fast bacillary lipoarabinomannan, particularly tubercle bacillary lipoarabinomannan, the antibody being set forth below:
| 03-24-2016 |
| 20160097768 | POLYVALENT CHIMERIC OSPC VACCINOGEN AND DIAGNOSTIC ANTIGEN - Chimeric polyvalent recombinant proteins for use as vaccines and diagnostics for Lyme disease (e.g. in canines and humans) are provided. The chimeric proteins comprise epitopes of the loop 5 region and/or the alpha helix 5 region of outer surface protein C (OspC) types and/or OspE types. The OspC types may be associated with mammalian | 04-07-2016 |
| 20160123967 | DETECTION OF PATHOGENS USING UNMODIFIED METAL NANOPARTICLES - The present disclosure relates to a method for the direct detection of pathogen in a sample using unmodified metallic nanoparticles, such as gold nanoparticles. The method may employ colorimetric detection. The combination of unmodified metallic nanoparticles and colorimetric detection provides a method that is simple, rapid, and economical compared to prior art methods that require modified nanoparticles or expensive detection equipment. The method does not require labeling of the target pathogen and is capable of detecting a broad spectrum of pathogens. | 05-05-2016 |
| 20160137723 | MONOCLONAL ANTIBODIES THAT REACT WITH THE CAPSULE OF BACILLUS ANTHRACIS - The present disclosure relates to monoclonal antibodies that bind poly-γ-D-glutamic acid (γDPGA), which is present on the surface of | 05-19-2016 |
| 20160146811 | OMPA AND ASP14 IN VACCINE COMPOSITIONS AND AS DIAGNOSTIC TARGETS - surface proteins Asp14 and OmpA and homologous genes from Anaplasmatacaea family members are used in compositions suitable for vaccines to treat or prevent infections caused by tick-born bacteria of the Anaplasmatacaea family. Asp14 and/or OmpA proteins or peptide fragments may be used in combination with other Anaplasmatacaea surface proteins to elicit an immune response. Furthermore, antibodies to Asp14 and/or OmpA proteins can be used in diagnostic methods to determine whether an individual has contracted an Anaplasmatacaea infection. Because of the conserved invasin domains in the surface proteins, a wide range of Anaplasmatacaea infections may be diagnosed, treated or prevented using compositions of the invention. | 05-26-2016 |
| 20160153974 | BIOSENSOR BASED ON MEASUREMENTS OF THE CLUSTERING DYNAMICS OF MAGNETIC PARTICLES | 06-02-2016 |
| 20160153988 | COMPOSITIONS AND METHODS FOR THE DETECTION OF ANAPLASMA PLATYS | 06-02-2016 |
| 20160202257 | MYCOPLASMA PNEUMONIAE IMMUNOLOGICAL DETECTION METHOD AND KIT | 07-14-2016 |
