| Entries |
| Document | Title | Date |
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| 20080202927 | Devices and methods for biochip multiplexing - The invention is directed to devices that allow for simultaneous multiple biochip analysis. In particular, the devices are configured to hold multiple cartridges comprising biochips comprising arrays such as nucleic acid arrays, and allow for high throughput analysis of samples. | 08-28-2008 |
| 20080202928 | MULTI-LAYER STRIP FOR USE IN MEASURING BIOLOGICAL MATERIAL AND SYSTEM FOR MEASURING BIOLOGICAL MATERIAL - The multi-layer strip for use in measuring biological material and the system for measuring a biological material are provided, wherein the multi-layer strip includes a stack of a plurality of strips, each having a flow channel and a reaction unit, and the strips may react with specific materials contained in a biological material injected into the multi-layer strip, whereby Thus, it is possible to quantitatively analyze various materials contained in a biological material and to optically and electrochemically measure and quantitatively analyze various materials in a biological material. | 08-28-2008 |
| 20080210557 | SUBCUTANEOUS GLUCOSE ELECTRODE - A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow “one-point” in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive species of serum or blood. The electrode is preferably three or four-layered, with the layers serially deposited within a recess upon the tip of a polyamide insulated gold wire. A first glucose concentration-to-current transducing layer is overcoated with an electrically insulating and glucose flux limiting layer (second layer) on which, optionally, an immobilized interference-eliminating horseradish peroxidase based film is deposited (third layer). An outer (fourth) layer is biocompatible. | 09-04-2008 |
| 20080223719 | Potentiostat circuit - A potentiostat is provided for a biosensor circuit and permits sequential and simultaneous measurements to be performed at different cells across a matrix of biosensing devices. Accordingly, a potentiostat comprises a first differential amplifier for receiving a scanning voltage at a first input terminal and a voltage at the reference electrode at a second input terminal and for generating an output voltage at an output terminal to be applied to the working electrode, wherein, when in use, a feedback loop of the potentiostat circuit is closed between the reference electrode and the working electrode. | 09-18-2008 |
| 20080237038 | Biostrip - The invention discloses a biostrip for the determination of the health condition or disease infection of an organism. The biostrip of the invention comprises at least an insulating baseboard and a capillary channel. Said insulating baseboard has at least one surface and a printed electrode is disposed on the surface. Moreover, said capillary channel is disposed above the insulating baseboard and has at least two ends on which at least one fixation reaction area and an exhaust channel of at least one direction are disposed respectively. The exhaust channel is formed by making use of the thickness and the shape of the back gum. Therefore, the biostrip of the invention can retain the advantage of the siphon type test strip of requiring a micro-amount of sample and also avoid the complicated production process thereof. | 10-02-2008 |
| 20080237039 | EXTRACELLULAR POTENTIAL SENSING ELEMENT, DEVICE FOR MEASURING EXTRACELLULAR POTENTIAL, APPARATUS FOR MEASURING EXTRACELLULAR POTENTIAL AND METHOD OF MEASURING EXTRACELLULAR POTENTIAL BY USING THE SAME - A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell. | 10-02-2008 |
| 20080251377 | Biosensor - A biosensor comprises a space part for sucking and housing a sample formed of two upper and lower plates, the two plates being stuck together by an adhesive layer, the space part for sucking and housing the sample being constituted so as to be partially opened in the peripheral part and partially closed by the adhesive layer, and has a working electrode having at least glucose oxidase immobilized thereon and a counter electrode on the same plane of the plate. | 10-16-2008 |
| 20080251378 | Biosensor - A biosensor comprises a space part for sucking and housing a sample formed of two upper and lower plates, the two plates being stuck together by an adhesive layer, the space part for sucking and housing the sample being constituted so as to be partially opened in the peripheral part and partially closed by the adhesive layer, and has a working electrode having at least glucose oxidase immobilized thereon and a counter electrode on the same plane of the plate. | 10-16-2008 |
| 20080257725 | Biosensor - A biosensor comprises a space part for sucking and housing a sample formed of two upper and lower plates, the two plates being stuck together by an adhesive layer, the space part for sucking and housing the sample being constituted so as to be partially opened in the peripheral part and partially closed by the adhesive layer, and has a working electrode having at least glucose oxidase immobilized thereon and a counter electrode on the same plane of the plate. | 10-23-2008 |
| 20080257726 | EXTRACELLULAR POTENTIAL SENSING ELEMENT, DEVICE FOR MEASURING EXTRACELLULAR POTENTIAL, APPARATUS FOR MEASURING EXTRACELLULAR POTENTIAL AND METHOD OF MEASURING EXTRACELLULAR POTENTIAL BY USING THE SAME - A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell. | 10-23-2008 |
| 20080257727 | EXTRACELLULAR POTENTIAL SENSING ELEMENT, DEVICE FOR MEASURING EXTRACELLULAR POTENTIAL, APPARATUS FOR MEASURING EXTRACELLULAR POTENTIAL AND METHOD OF MEASURING EXTRACELLULAR POTENTIAL BY USING THE SAME - A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell. | 10-23-2008 |
| 20080277275 | TREATMENT APPARATUS, SOLUTION STIRRING METHOD AND SOLUTION TRANSFER METHOD - The electrolytic reaction of a solution supplemented with oxidation-reduction substances is caused in a magnetic field. Lorentz force generated by the interaction between an electrolytic current and the magnetic field is utilized. As a result, the effective stirring or transfer of a solution as well as the detection of a biologically relevant substance with high precision can be achieved without causing the aggregation or uneven distribution of magnetic beads or the like. | 11-13-2008 |
| 20080283396 | Analyte Sensor with Insertion Monitor, and Methods - A sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector. | 11-20-2008 |
| 20080296154 | Analysis Device - An analysis device is provided for analysing a substance sample. The device comprises a plurality of sample activatable battery cells connected in series. | 12-04-2008 |
| 20080302659 | ELECTROCHEMICAL BIOSENSORS AND ARRAYS - Electrochemical sensor devices are provided, in various amperometric, potentiometric, and conductometric sensor device configurations. An amperometric sensor device may include a structural body which has at least one reservoir that has at least one opening; a working electrode located within the reservoir; analyte sensor chemistry located within the reservoir and deposited on at least the working electrode; an auxiliary electrode located outside of the reservoir; a reference electrode; at least one reservoir cap closing the opening to isolate the working electrode and analyte sensor chemistry within the reservoir and to prevent an analyte outside of the reservoir from contacting the analyte sensor chemistry; and means for rupturing or displacing the reservoir cap to permit the analyte from outside of the reservoir to contact the analyte sensor chemistry. | 12-11-2008 |
| 20080308418 | Adhesion of Membranes on Nitride Layer in Electrochemical Sensors by Attachment to Underlying Oxide Layer - An electrochemical sensor is provided that exhibits improved adhesion of the membrane to the nitride layer used as an insulating layer in silicon- or silicon-oxide-based electrochemical sensing devices. The sensing devices include a substrate, an oxide disposed on the substrate, a nitride disposed on the oxide, an electrically conductive structure disposed on the oxide layer, and an electrode disposed on the oxide layer and electrically coupled to the electrically conductive structure. At least one opening is formed in the nitride layer to form at least one adhesion trench that exposes a surface region of an oxide layer underlying the nitride layer. The membrane covers the electrode, and contacts the oxide surface regions exposed by the adhesion trenches. The contact between the membrane and the oxide surface region provides for improved adhesion of the membrane to the electrochemical sensing device. | 12-18-2008 |
| 20080314745 | Biosensor and its production - Biosensor for analyzing biological fluids having:
| 12-25-2008 |
| 20080314746 | Analyzer - It is an object of this invention to measure small amounts of a plurality of sample solutions at the same time. The small amounts of sample solutions are respectively placed on measuring electrodes, a medium is placed across the plurality of sample solutions, a liquid joint of a reference electrode is brought into contact with the medium, and a potential difference between each of the measuring electrodes and the reference electrode via the medium is measured. | 12-25-2008 |
| 20090014327 | Analyte Test Sensor and Method of Manufacturing the Same - An analyte test sensor for use in measuring the concentration of a particular analyte in a test sample includes a non-conductive substrate, a reference electrode deposited on the substrate, a working electrode deposited on the substrate and a compensation electrode deposited on the substrate. The compensation electrode is provided with a resistive ladder and is designed to correct for test result inaccuracies which are the result of variances in the manufacturing of the test sensor. Specifically, in one embodiment, the compensation electrode corrects for test result inaccuracies in an analog manner by shunting a portion of the working current away from working electrode. In another embodiment, the compensation electrode corrects for test result inaccuracies in a digital manner by providing a calibration code which is proportional its resistance value. A batch of analyte test sensors are preferably manufactured in the following manner. An initial batch of the test sensors is constructed. Then, a limited sampling of the sensors is tested for accuracy using a control sample. Based on the test results, the resistance value of the compensation electrode for each remaining sensor in the batch is adjusted accordingly. | 01-15-2009 |
| 20090045054 | APPARATUS AND METHOD FOR ELECTROMAGNETICALLY DETECTING MICROORGANISM - An apparatus and a method for electromagnetically detecting microorganisms. The apparatus includes a pair of first electrodes which are positioned to be opposite to each other on a measuring cell and are connected to a power supply to generate an electric field around a solution contained in the measuring cell, a magnetic field generating unit which generates a magnetic field around the solution contained in the measuring cell in a perpendicular direction to the electric field, second electrodes which are positioned perpendicularly to both the electric field and the magnetic field, and a voltage measurer which measures the voltage generated between the second electrodes as the microorganisms move in the measuring cell. The apparatus determines the presence, quantity and identity of microorganisms with negative surface charge with improved sensitivity using the Hall effect. | 02-19-2009 |
| 20090057146 | ANALYTE TEST STRIP WITH IMPROVED REAGENT DEPOSITION - An analyte, system, strip and method are described. In one example, an analyte test strip is provided that includes a substrate, electrically conductive material and an isolated portion of the electrically conductive material. The substrate has a generally planar surface that extends from a first end to a second end. The electrically conductive material is disposed on the generally planar surface to define a plurality of electrodes spaced apart from each other. The isolated portion of the electrically conductive material is disposed between at least two electrodes so that the isolated portion is not in electrical communication with the plurality of electrodes. | 03-05-2009 |
| 20090057147 | Devices and methods for biochip multiplexing - The invention is directed to devices that allow for simultaneous multiple biochip analysis. In particular, the devices are configured to hold multiple cartridges comprising biochips comprising arrays such as nucleic acid arrays, and allow for high throughput analysis of samples. | 03-05-2009 |
| 20090057148 | In Vivo Analyte Monitor With Malfunction Detection - The measuring system for in vivo monitoring of an analyte concentration with malfunction detection, comprises an electrode system, a potentiostat and an evaluation unit. The electrode system has a working electrode, a reference electrode, and a counter electrode. The potentiostat is for adjusting a difference of potential between the electric potential of the working electrode and the electric potential of the reference electrode to a specified value and for measuring an electric current flowing between the working electrode and the counter electrode. The potentiostat comprises a working electrode terminal for connection to the working electrode, a reference electrode terminal for connection to the reference electrode, and a counter electrode terminal for connection to the counter electrode. The evaluation unit monitors the electric potential of the counter electrode and generates a malfunction signal when said potential is outside a specified reference range. A method of operation is also disclosed. | 03-05-2009 |
| 20090057149 | Method of Manufacturing a Diagnostic Test Strip - A method for manufacturing a biosensor is provided. The method may include positioning a shadow mask containing a pattern of a plurality of feature sets over a substantially planar base layer containing a plurality of registration points. The method may also include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the shadow mask and removing the shadow mask from the substantially planar base layer. Alternatively, the method may include providing a laminate structure including a substantially planar base layer containing a plurality of registration points and a photoresist layer containing a pattern of a plurality of feature sets. The method may further include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the photoresist layer and removing the photoresist layer from the substantially planar base layer. | 03-05-2009 |
| 20090065355 | BIOSENSOR CAPABLE OF SIMULTANEOUS DETECTION OF SUBSTRATE BINDING AND REACTION PRODUCT - An object of the present invention is to provide a biosensor that can detect binding of a compound with a functional protein and then assay a reaction product derived from the activity of the functional protein again. The present invention provides a biosensor for detecting a test molecule specifically binding to a physiologically active substance, which comprises; (1) (a) a first reaction region on which the physiologically active substance has been immobilized for performing a binding reaction between the physiologically active substance and the test molecule and a physiologically active reaction caused by the physiologically active substance, and (b) a second reaction region on which a molecule that specifically binds to a reaction product resulting from the physiologically active reaction has been immobilized for performing a binding reaction between the reaction product and the molecule that specifically binds to the reaction product, in the same area; and (2) an assay region for detecting changes in the binding reaction in the first reaction region and in the binding reaction in the second reaction region. | 03-12-2009 |
| 20090090623 | Biosensor having integrated heating element and electrode with metallic catalyst - The invention discloses a biosensor includes a strip having an integrated heating element and an electrode with metallized graphite including metal in the range of 0.1-5% in weight; graphite in the range of below 55% in weight; and polymer. The biosensor further includes an electric measuring device having a slot enabling the strip to insert therein. | 04-09-2009 |
| 20090095622 | Biosensor and method to produce biosensor - A biosensor is a sensor strip that is folded to form a base and a cover. The base has a reactive layer, two electrodes, a compensating electrode and a variable resistive pad. The reactive layer is formed on the base. The electrodes are formed on the base and connect to the reactive layer to an end of the base. The compensating electrode is formed between the electrodes and is connected to one electrode by the variable resistive pad having an adjustable resistivity to account for manufacturing errors. The cover is shorter than and adhered to the base and has a sample-dropping section corresponding to the reactive layer to allow a liquid sample to be added to the reactive layer. Operators insert the biosensor into the biosensor detector and obtain a correct result without calibrating the biosensor detector so preventing human calibration errors. | 04-16-2009 |
| 20090095623 | Identification Method for Electrochemical Test Strips - The present invention provides a method and apparatus for creating test strips that may be identified based on differences in electrical conduction or resistance between contact point on the test strip. This is achieved by creating a base test strip with contact points that may be connected to other contact points by an electrical connection. These base test strips may be modified to create a difference in electrical conductivity between contact points, or a contact point may be eliminated. This modification can be used to distinguish different types of test strips based on electrical signature. Additionally, the base test strip may be created such that multiple modifications are possible to distinguish numerous characteristics of test strips. | 04-16-2009 |
| 20090095624 | Electroactive complex, electroactive probe and preparation method - Organic electrodes produced from electroactive polymers bonded to anti-ligands intended to interact specifically with ligands. | 04-16-2009 |
| 20090127112 | Biologically active metal-coated proteins - Metal-coated proteins, being dissolvable or suspendable in aqueous media and/or retaining a biological activity of the protein, a process and intermediates for preparing same are disclosed. Further disclosed are a pharmaceutical composition containing and a method of treating bacterial and fungal infections utilizing biologically active metal-coated proteins. Conductive elements, electronic circuits containing same, electrodes and biosensor systems utilizing same, and imaging probes, all containing the metal-coated proteins, are also disclosed. | 05-21-2009 |
| 20090127113 | Microfluidic detector and manufacturing method - A micro-fluidic detector applied for detecting analytes in a fluid sample is disclosed. The micro-fluidic detector comprises a mixing area, a flow area and at least one detection module. The mixing area has a conductive top plate and a plurality of first electrodes for mixing a first fluid and a second fluid so as to form the fluid sample. The flow area has two second electrodes, positioned side by side, for driving the fluid sample to flow. The detection module is used for detecting analytes in the fluid sample flowing in the flow area. The mixing area uniformly mixes the first fluid and the second fluid via an electric field generated by applying a voltage potential, with respect to the conductive top plate, to one by one of the first electrodes in the mixing area. The flow area drives the fluid sample via an electric field generated by the second electrodes. | 05-21-2009 |
| 20090145753 | Biomechanical test system, measurement device, and biochemical test strip - A biochemical test system, a measurement device, and a biochemical test strip are provided. The biochemical test strip includes an insulating substrate, an electrode system disposed on the insulating substrate, and an identifying unit disposed on one side of the insulating substrate. The identifying unit includes N components, and at least one of the N components includes a groove. It should be noted that the term “N” in this specification is an integer greater than two. The measurement device includes a microprocessor and a connector, wherein the connector is coupled to the identifying unit for receiving a signal of an identification code corresponding to the identifying unit, and the microprocessor is coupled to the connector for receiving the signal from the connector. | 06-11-2009 |
| 20090152110 | Chip For Cell Electrophysiological Sensor, Cell Electrophysiological Sensor Using The Same, and Manufacturing Method of Chip for Cell Electrophysiological Sensor - A chip for a cell electrophysiological sensor has a substrate. The substrate has a through-hole formed from the upside to the downside, and the opening of the through-hole is formed in a curved surface curved from the upside and downside of the substrate toward the inner side of the through-hole. In this configuration, the electrolyte solution (first electrolyte solution and second electrolyte solution) flows more smoothly, and the sample cell can be sucked accurately, and the trapping rate of the sample cells is improved. | 06-18-2009 |
| 20090178923 | ELECTROCHEMICAL SENSOR FOR THE DETERMINATION OF AN ANALYTE CONCENTRATION - The invention relates to an electrochemical sensor for the determination of a concentration of at least one analyte in a medium, in particular a body tissue and/or a body fluid, to an apparatus that includes the electrochemical sensor, and to a use of the electrochemical sensor, and finally to a method for producing it. The electrochemical sensor has an isolation element and at least two electrodes. The at least two electrodes comprise at least one working electrode and at least one further electrode, in particular at least one counter electrode and/or at least one reference electrode. The at least two electrodes run parallel to one another and form an electrochemical measuring cell of the electrochemical sensor. | 07-16-2009 |
| 20090188791 | Biosensor and its production - Biosensor by means of which biological fluids are analysed, comprising at least the
| 07-30-2009 |
| 20090194415 | PAIR OF MEASURING ELECTRODES, BIOSENSOR COMPRISING A PAIR OF MEASURING ELECTRODES OF THIS TYPE, AND PRODUCTION PROCESS - A pair of measuring electrodes comprising a first and a second, preferably in each case sheet-like electrode comprises an insulation layer arranged between said electrodes. One or more nanopores, which extend through said insulation layer as far as said first electrode, the surface of which is at least partially uncovered by said nanopores, are provided in each second electrode. The invention also describes a biosensor comprising a pair of measuring electrodes of this type, an electrochemical cell comprising a biosensor of this type and a process for producing said pair of measuring electrodes. | 08-06-2009 |
| 20090260985 | ANALYTE SENSOR WITH INSERTION MONITOR, AND METHODS - A sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector. | 10-22-2009 |
| 20090308741 | Sensor arrangement comprising an electrode for detecting diffused loaded particles - A sensor arrangement for detecting particles potentially contained in an analyte is disclosed. The arrangement includes a substrate; at least one sensor electrode which is arranged on and/or in the substrate and on which scavenger molecules, which hybridize with particles that are potentially contained in an analyte and are to be detected, are immobilized, electrically charged particles generated by hybridization being detectable on the at least one sensor electrode; and at least one diffusion detection electrode which is arranged in a surrounding region of the at least one sensor electrode and is embodied in such a way that it detects electrically charged particles that are generated by hybridization and can be diffused away by the at least one sensor electrode. | 12-17-2009 |
| 20100000861 | PACKAGING SYSTEM FOR TESTING DEVICES - A packaging system is disclosed. The packaging system comprises an analyte-testing device including a fluid-receiving portion. The packaging system further comprises a film adapted to cover the fluid-receiving portion of the analyte-testing device. The film has a first side and an opposing second side. The first side is adapted to contact the analyte-testing device. The packaging system further comprises adhesive positioned on at least a portion of the first side of the film. The packaging system further comprises a desiccant material positioned on the first side of the film such that the desiccant material is adapted to be in vapor communication with the fluid-receiving portion of the analyte-testing device. | 01-07-2010 |
| 20100051455 | BIOSENSOR TEST STRIP CARDS - An analyte test strip card comprises a plurality of biosensor test strips each having a reagent portion and a releasable and recloseable cover that overlaps the reagent portion. The strips are in a two dimensional array and are at least partially retained by a substantially credit card sized platform. Each strip is connected to adjacent strips by a first means for separation. At least some of the strips are connected to the retaining platform by a second means for separation. | 03-04-2010 |
| 20100051456 | ANALYSIS IMPLEMENT WITH OPENING IN INSULATION FILM - The present invention relates to an analytical tool (X) which includes a substrate ( | 03-04-2010 |
| 20100084267 | PAIR OF MEASURING ELECTRODES, BIOSENSOR COMPRISING A PAIR OF MEASURING ELECTRODES OF THIS TYPE, AND PRODUCTION PROCESS - A pair of measuring electrodes comprising a first and a second, preferably in each case sheet-like electrode comprises an insulation layer arranged between said electrodes. One or more nanopores, which extend through said insulation layer as far as said first electrode, the surface of which is at least partially uncovered by said nanopores, are provided in each second electrode. The invention also describes a biosensor comprising a pair of measuring electrodes of this type, an electrochemical cell comprising a biosensor of this type and a process for producing said pair of measuring electrodes. | 04-08-2010 |
| 20100089750 | RF Tag on Test Strips, Test Strip Vials and Boxes - A glucose monitoring system, includes a glucose sensor strip or package of strips. The strip includes a substrate and a glucose monitoring circuit that has electrodes and a bodily fluid application portion of selected chemical composition. An antenna is integrated with the glucose sensor strip. A RFID sensor chip is coupled with the glucose sensor strip and the antenna. The chip has a memory containing digitally-encoded data representing calibration and/or expiration date information for the strip. | 04-15-2010 |
| 20100116655 | CHEMICAL MESSENGER SENSOR - A sensor for the detection of chemical messengers is described herein. In particular a sensor for the detection of catecholamines, for example dopamine, epinephrine or norepinephrine, is reported. Catecholamines play pivotal roles as neurotransmitters and hormones in the human body. An electrode for detecting a catecholamine comprising a conducting or semi-conducting substrate, and a polymer comprising polyethylenedioxythiophene on said substrate is disclosed. The polymer is doped with a cyclodextrin macrocycle. Suitable cyclodextrin macrocycles include anionic cyclodextrin macrocycles, for example sulfonated β-cyclodextrins (CDs). Also, disclosed in sensor capable of selectively detecting a catecholamine in the presence of ascorbic acid (ascorbate). | 05-13-2010 |
| 20100122904 | INCORPORATING CMOS INTEGRATED CIRCUITS IN THE DESIGN OF AFFINITY-BASED BIOSENSOR SYSTEMS - A biosensor system incorporating CMOS integrated circuits. In one type of biosensor system, the biosensor system includes a complementary metal-oxide-semiconductor (“CMOS”) integrated circuit. The biosensor system further includes an optical filter fabricated on the CMOS integrated circuit. Additionally, a plurality of capturing probes is optically coupled to the CMOS integrated circuit. Alternatively, another type of biosensor system includes a silicon substrate. The alternative biosensor system further includes active devices fabricated on the silicon substrate. Additionally, the alternative biosensor system includes a plurality of metal layers stacked on top of the active devices. Furthermore, the alternative biosensor system includes a passivation layer covering a top metal layer, where the passivation layer includes an opening configured to expose the top metal layer, where the opening is used as a sensing electrode. Additionally, the alternative biosensor system includes a plurality of probes attached to the sensing electrode. | 05-20-2010 |
| 20100126856 | Analyte Test Instrument Having Improved Versatility - An analyte test instrument that has a test strip circuitry that can be configured using information provided by a calibration strip to perform assays with test strips having two electrodes and test strips having three electrodes. The analyte test instrument of this invention comprises:
| 05-27-2010 |
| 20100133098 | Methods and Devices for Concentration and Purification of Analytes for Chemical Analysis Including Matrix-Assisted Laser Desportion/Ionization (MALDI) Mass Spectrometry (MS) - Analytical methods and devices are disclosed for separating low abundance analytes by electrophoretically driving the analytes through a sieving matrix to first remove high molecular weight species. Subsequently the remaining low abundance analytes are electrophoretically focused onto a capture membrane where the analytes become bound within a small capture site. After this step the capture membrane may be allowed to dry and then attached to a conductive MALDI sample plate. | 06-03-2010 |
| 20100133099 | ELECTRONIC DEVICE ASSEMBLY WITH SAFETY ELECTRIC CONNECTOR - The application provides an assembly comprising a housing ( | 06-03-2010 |
| 20100133100 | SENSOR AND APPARATUS FOR ANALYSING GASES PRESENT IN BLOOD - A galvanic sensor for analyzing gases present in blood includes a duct suitable for being crossed by a flow of gas and provided with an inlet opening and an outlet opening, a reference galvanic element including a container containing an electrolytic solution in which a reference electrode is inserted, and a measuring galvanic element. The container is fixed to the duct and the measuring galvanic element includes a measuring electrode arranged transversally to the axis of the duct and a filiform element having a high capillarity so as to act as a wick. The filiform element is anchored to the container and has a first end contacting the measuring electrode and a second end contacting the electrolytic solution. The measuring element of the galvanic sensor is extremely miniaturized and allows to detect in real time and continuously gases in traces, on the order of parts per million or even lower. | 06-03-2010 |
| 20100140087 | BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode | 06-10-2010 |
| 20100147683 | NOVEL POTENTIOMETRIC CHOLESTEROL SENSOR FOR THE QUANTITATIVE ESTIMATION OF TOTAL CHOLESTEROL IN HUMAN BLOOD SERUM - The present invention provides a novel sensor for the estimation of total cholesterol in human blood serum using molecular imprint of cholesterol. Human blood serum contains 150-250 mg/dl cholesterol. The present invention provides a sensor device and a process for the fabrication of ISFET (Ion Selective Field Effect Transister) coated with molecular imprint of cholesterol on the SiO | 06-17-2010 |
| 20100170788 | ELECTROSENSING ANTIBODY-PROBE DETECTION AND MEASUREMENT SENSOR USING CONDUCTIVITY PROMOTION BUFFER - A sensor system for electrosensing an antigen in a test sample is disclosed. The sensor system has two electrodes electrically disconnected and physically separated from each other, and a layer of antibody is immobilized on the surface of the electrodes. The antibody has specific binding reactivity with the antigen. Conductivity promotion molecules suspended in a buffer solution may be distributed over and/or between the antibody-populated electrodes for improving electrical conductivity characteristics across the two electrodes. The antibody captures the antigen present in the test sample mixed in the buffer solution that comes into contact with the antibody-populated electrodes. This alters the electrical conductivity characteristic across the two electrodes in which an amount representative of the altering provides an indication for electrosensing of the antigen. | 07-08-2010 |
| 20100170789 | Microanalytical chip - Provided is a microanalytical chip that is capable of controlling sequential sending of a plurality of solutions of mutually different viscosities and interfacial tensions. The microanalytical chip includes: a main conduit including a detecting portion and/or a reacting portion; a first introduction conduit and a second introduction conduit for introducing a solution to the main conduit from a further upstream position than the detecting portion and the reacting portion; and a third introduction conduit for introducing a. solution to the main conduit, wherein W2| 07-08-2010 | |
| 20100170790 | BIOSENSOR - A sensor includes a diaphragm having a through-hole ( | 07-08-2010 |
| 20100170791 | BIOSENSOR AND READOUT METER - The present invention relates to a biosensor for selectively performing quantitative analysis on a specific substance contained in a biological sample and a readout meter using the same. The inventive biosensor comprises an electrode for recording identification information of the biosensor thereon. The electrode has an electrode pattern and a plurality of contact points formed thereon according to the identification information, and the identification information is recorded on the electrode based on the ratio of resistances between the plurality of contact points. According to the present invention, various items of identification information such as in | 07-08-2010 |
| 20100187106 | ULTRA-SENSITIVE, PORTABLE CAPILLARY SENSOR - A portable, lightweight, rugged, easy-to-operate biosensor useful for rapidly detecting cells, viruses, antibodies, and other proteins. A capillary tube has a capture antibody immobilized on its interior surface. The specific capture antibody is selected based upon a desired target analyte to be detected. A sample potentially containing the target antigen is introduced into the capillary tube. Thereafter, a second antibody labeled with a fluorescent dye is introduced. Upon excitation by electromagnetic energy, typically supplied by a laser, the fluorescence of the sample is captured and analyzed. The apparatus is extremely compact and rugged making it ideal for field use. In addition, accurate results may be obtained by relatively unskilled operators directly from a self-contained readout. Optionally, an external device (e.g., a computer) may be connected to the apparatus via an optional interface. The analysis time provided by the biosensor system of the invention is shorter than has heretofore been possible. | 07-29-2010 |
| 20100213056 | Interaction Detecting Portion with Electrode Having the Same Potential, Sensor Chip Using the Same, and Interaction Detector - There are provided an interaction detecting portion including an interaction region in the whole of which an electrodynamic effect is obtained, and which has a simpler structure, and the like. There is provided an interaction detecting portion | 08-26-2010 |
| 20100219071 | BIOSENSOR - The present invention relates to a biosensor. The biosensor includes a support substrate, an electrically conductive coating positioned on the support substrate, the coating being formed to define electrodes and a code pattern, wherein there is sufficient contrast between the conductive coating and the substrate such that the code pattern is discernible, and a cover cooperating with the support substrate to define a channel. At least a portion of the electrodes are positioned in the channel. | 09-02-2010 |
| 20100224487 | Biosensor having identification information and apparatus for reading identification information of biosensor - A biosensor is provided, including an identification information recording unit having identification information of the biosensor recorded thereon, where the identification information recording unit is a color tag that is attached on the biosensor and indicates the identification information by color, chroma of color, or arrangement pattern of colors. An apparatus for reading identification information of a biosensor is provided, including: a biosensor sensing unit detecting the biosensor; a light-emitting unit emitting light on an identification information recording unit when the biosensor sensing unit detects the biosensor, the identification information recording unit having the identification information of the biosensor recorded thereon; a light-receiving unit that receives the light emitted from the light-emitting unit, and reflected or refracted by or passing through the identification information recording section; and an identification information reading unit analyzing the light received by the light-receiving unit and reading the identification information of the biosensor. | 09-09-2010 |
| 20100230284 | REAGENT DEVICES - A reagent device such as an electro-chemical micro-electrode sensor is provided with one or more reagent modules to carry respective reagents. The device includes respective receiving stations for receiving the reagent modules on board. The reagent modules may be tested independently before assembly of the device and hence yields are improved. | 09-16-2010 |
| 20100243441 | BIOSENSOR WITH PREDETERMINED DOSE RESPONSE CURVE AND METHOD OF MANUFACTURING - The present invention provides a system of biosensors whose dose-response curves are maintained within a predetermined and desired range or tolerance during production by selecting a feature of the biosensors that can be varied during production. For example, in one exemplary embodiment the effective area of the working electrode of an electrochemical biosensor can be varied during production as needed to offset variations that occur, e.g., in the reagent of the biosensors as production proceeds. In another exemplary embodiment, the dose-response curve of biosensors not yet produced can be predicted and one or more features of these biosensors can be selected to maintain the dose-response curve within a predetermined range or tolerance. | 09-30-2010 |
| 20100252429 | ION-SELECTIVE ELECTRODE - A five-part electrode device, including a membrane formed in situ, which is useful in automated clinical chemistry analyzers, and the method of forming a direct solid state connection to the membrane eliminating the need for the use of an internal reference electrode requiring internal filling solutions. | 10-07-2010 |
| 20100258438 | BIOSENSOR - In a biosensor that detects introduction of a sample liquid into a specimen supply path using a detecting electrode, a means of improving accuracy of detection is provided. The biosensor has: an electrode system including measuring electrode, counter electrode, and detecting electrode on first electrically insulating support; specimen supply path for introducing the sample liquid; and reagent layer used for quantifying a substrate contained in the sample liquid. The means is characterized in that detecting electrode is spaced from measuring electrode by a distance sufficient for the sample liquid to sufficiently cover measuring electrode before the sample liquid reaches detecting electrode. | 10-14-2010 |
| 20100264024 | BIOCHIP, BIOSENSOR AND INSPECTION SYSTEM - A biochip, includes: an ink-jet head portion detachably mountable to a biosensor; a sensing electrode formed with a work electrode, a reference electrode, and a counter electrode; and a thin film transistor. | 10-21-2010 |
| 20100270149 | Smart Sensor Ports and Methods of Using Same - The present disclosure provides an orientation-nonspecific sensor port for use in analyte meters designed to detect and quantify analyte levels in a fluid sample along with methods of using the same. The present disclosure also provides compositions and methods for facilitating the correct insertion of a sensor into a corresponding analyte meter. | 10-28-2010 |
| 20100270150 | Smart Sensor Ports and Methods of Using Same - The present disclosure provides an orientation-nonspecific sensor port for use in analyte meters designed to detect and quantify analyte levels in a fluid sample along with methods of using the same. The present disclosure also provides compositions and methods for facilitating the correct insertion of a sensor into a corresponding analyte meter. | 10-28-2010 |
| 20100288632 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 11-18-2010 |
| 20100320086 | FLEXIBLE BIOSENSOR AND MANUFACTURING METHOD FOR THE SAME - Provided are a flexible biosensor using a gold binding substance and a method for manufacturing the same. | 12-23-2010 |
| 20110000785 | ELECTRICAL PATTERNS FOR BIOSENSOR AND METHOD OF MAKING - The present invention provides an inventive biosensor that includes multiple regions in which the electrical pattern is formed from different electrically conductive materials. The present invention also provides an inventive method for mass producing biosensors as just described. In one embodiment of this method, first and second different electrically conductive materials are deposited side by side on a portion of an electrically insulating base material, and a plurality of electrical patterns is formed on the portion of the base material. Each electrical pattern includes a first region formed from the first electrically conductive material electrically connected to a second region formed from the second electrically conductive material. The electrically conductive materials can be deposited as layers on the base material and portions of the layers can be removed to form the electrical patterns, or, the electrical patterns can be formed by transferring the conductive material in the shape of the electrical pattern directly to the base material, such as by a laser direct transfer technique. | 01-06-2011 |
| 20110017592 | BIOSENSOR - An electrode assembly that may be used, for example, for electrochemically analysing a sample to determine the presence (or otherwise) of a species having biomembrane activity comprises at least one working electrode comprised of a conductive carrier substrate having a surface coated with mercury immobilised on the surface of the substrate. The surface of the mercury remote from said substrate is coated with a phospholipid layer. The preferred carrier substrate is platinum. The electrode assembly may be incorporated in a flow cell. | 01-27-2011 |
| 20110017593 | HIGHLY SENSITIVE BIOSENSOR, BIOCHIP COMPRISING THE SAME AND METHOD FOR MANUFACTURING THE SAME - The present invention has a feature to form a biocompatible dielectric thin film on the surface of a metal electrode in a biosensor constructing a biochip. When using such a biocompatible dielectric thin film, this non-specific adsorption between a protein such as enzyme and a metal electrode can be prevented. Therefore, the present invention can escape a phenomenon that inhibits the reaction of a biomolecule due to the non-specific adsorption on the surface of a metal electrode. In addition, when the dielectric thin film having a high dielectric constant, as a biocompatible dielectric thin film, is made on the surface of a metal electrode, the sensitivity of an electrical detection according to the reaction of a biomolecule can be improved. | 01-27-2011 |
| 20110036712 | ANALYZING SYSTEM - The present invention relates to an analysis system including a laser beam oscillator | 02-17-2011 |
| 20110036713 | BIOSENSOR - A biosensor can supply a sample solution accurately and easily, and includes a capillary for collecting a sample solution and analyzes a specific substance in the sample solution, an air hole, and at least two supply ports, i.e., a sample supply port and an auxiliary sample supply port, so that supply of the sample solution can be performed from either of the supply ports. Even when the sample supply port is closed up with a fingertip or the like and supply of the sample solution is stopped, the sample solution can be quickly supplied from the other auxiliary sample supply port. | 02-17-2011 |
| 20110042210 | METHOD FOR PREPARING METAL NANOPARTICLES USING METAL SEED AND METAL NANOPARTICLES COMPRISING METAL SEED - The invention relates to a method of manufacturing metal nanoparticles by using metal seed and metal nanoparticles including such metal seed. It is to provide the Au nanoparticles prepared by a method comprising: preparing a solution by adding a monosurfactant into a non-aqueous solvent; heating the solution; preparing a platinum seed solution by adding platinum salt chosen form platinum, palladium, iridium into the heated solution; and adding gold salt in the platinum seed solution. | 02-24-2011 |
| 20110048938 | METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS - A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes. | 03-03-2011 |
| 20110073474 | SURFACE ACOUSTIC WAVE DEVICE AND SURFACE ACOUSTIC WAVE BIOSENSOR - A surface acoustic wave device, including: a piezoelectric substrate; an interdigitated transducer electrode disposed on the substrate; an oxide film disposed on surface of the interdigitated transducer electrode; and a hydrophobic film disposed on a surface of the oxide film. | 03-31-2011 |
| 20110073475 | Analyte Sensor - An analyte sensor configured to be implanted in the body of the user unassisted by an introducer sharp. | 03-31-2011 |
| 20110073476 | Stackable Electrochemical Analyte Sensors, Systems and Methods Including Same - In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a bio-fluid sample. The analyte sensor has a base with first and second ends, a concave recess in the first end, a second end receiving surface, and a sidewall extending between the ends. An electrode may be provided on the receiving surface with an electrochemically-active region coupled to the electrode. A conductor in electrical contact with the electrode may extend along the sidewall and may be adapted to be in electrical contact with a first contact of an analyte meter. Manufacturing methods and systems utilizing and dispensing the analyte sensors are provided, as are numerous other aspects. | 03-31-2011 |
| 20110120864 | CELLULAR ELECTROPHYSIOLOGY SENSOR CHIP AND CELLULAR ELECTROPHYSIOLOGY SENSOR USING THE CHIP, AND METHOD OF MANUFACTURING CELLULAR ELECTROPHYSIOLOGY SENSOR CHIP - A cellular electrophysiology sensor is adapted to measure an electrical change of a test cell. A chip for the sensor includes a diaphragm, and a thermally-oxidized film mainly containing silicon dioxide on the diaphragm. The diaphragm includes a silicon layer and a silicon dioxide layer on an upper surface of the silicon layer. A through-hole passing through the silicon layer and the silicon dioxide layer is formed. The through-hole has an opening which opens at the silicon dioxide layer and is adapted to capture the test cell. The thermally-oxidized film is provided on an inner wall surface of the through-hole, and unified with the silicon dioxide layer at the opening of the through-hole. This cellular electrophysiology sensor chip can stably capture the test cell and provides a gigaseal stably even if test cells have different properties, | 05-26-2011 |
| 20110132759 | Biosensors and Methods of Making - Devices and methods for determining the concentration of an analyte in a sample of liquid are provided. | 06-09-2011 |
| 20110174613 | Biosensor, thin film electrode forming method, quantification apparatus, and quantification method - A biosensor is disclosed comprising a support; a conductive layer composed of an electrical conductive material such as a noble metal, for example gold or palladium, and carbon; slits parallel to and perpendicular to the side of the support; working, counter, and detecting electrodes; a spacer which covers the working, counter, and detecting electrodes on the support; a rectangular cutout in the spacer forming a specimen supply path; an inlet to the specimen supply path; a reagent layer formed by applying a reagent containing an enzyme to the working, counter, and detecting electrodes, which are exposed through the cutout in the spacer; and a cover over the spacer. The biosensor can be formed by a simple method, and provides a uniform reagent layer on the electrodes regardless of the reagent composition. | 07-21-2011 |
| 20110186428 | ELECTRODE ARRANGEMENTS FOR BIOSENSORS - The present invention relates to a biosensor. The biosensor includes a support substrate, electrodes positioned on the support substrate, a spacer substrate positioned on the support substrate, and a cover positioned on the spacer substrate. The cover cooperates with the support substrate to define a capillary channel. The electrodes include at least one working electrode defining a working electrode area in the capillary channel. The working electrode is configured to minimize variation in the working electrode area in the capillary channel due to variations in the spacer substrate placement relative to the working electrode. | 08-04-2011 |
| 20110192720 | MICROFABRICATED LIQUID-JUNCTION REFERENCE ELECTRODE - Micromachined reference electrodes for use in miniaturized electrochemical sensors, and methods for fabricating such reference electrodes and electrochemical sensors, for example, as a part of a microfluidic system, are disclosed. Electrochemical measurements allow for inexpensive detection of a wide variety of (bio-)chemical compounds in solution. The reference electrode is one of the main parts of an electrochemical cell. The reference electrode, from which no current is drawn, has a stable, constant potential. | 08-11-2011 |
| 20110198222 | ELECTROLYTE SENSOR USING CONDUCTIVE ELASTOMER - An electrolyte sensor that uses conductive elastomer electrodes. Examples of the intended analytes for sensor use include those found in urine, saliva, blood, feces and spinal fluid, although other analytes exist for electrolyte detection. Conductive elastomer trace electrodes are separated by a gap or channel which can be bridged by an electrolyte and thereby complete an electrical circuit to an alarm or other circuitry. Gap or channel distances vary the level of electrical resistance associated with detecting certain analytes. | 08-18-2011 |
| 20110203923 | SENSING APPARATUS AND PROCESS - A sensing apparatus with a connector, a sensor lead and a sensor module with a spacer placed over electrodes that have been deposited on a substrate. The spacer may have a space for receiving an enzyme. End portions of the sensor module may be encapsulated, such as with molded beads. A sensor lead may attach to the sensor module and may have an outer tubing that passes over the module and attaches to the beads at the end of the sensor module. The sensor lead may also attach to the connector such that the sensing apparatus may be electrically coupled to a pump, electronics or other devices. The sensing apparatus may be implanted into a vein or artery. | 08-25-2011 |
| 20110203924 | Assay Plates, Reader Systems and Methods for Luminescence Test Measurements - Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence. | 08-25-2011 |
| 20110266149 | ELECTROCHEMICAL SENSOR MODULE - A sensor module includes a flexible linkage; an analysis cell housing; a member anchor; a piercing member; and an electrode arrangement. The analysis cell housing defines an analysis cell and a passageway providing access to the analysis cell from a sample port of the analysis cell housing. The member anchor is configured to move relative to the analysis cell housing along the axis defined by the passageway. The piercing member is configured to slide from a retracted position to an extended position when the member anchor is moved relative to the analysis cell housing. The electrode arrangement is arranged in fluid communication with the analysis cell housing. | 11-03-2011 |
| 20110278167 | Biosensor, thin film electrode forming method, quantification apparatus, and quantification method - A biosensor according to the present invention comprises a support | 11-17-2011 |
| 20110315548 | BIOLOGICAL SIGNAL DETECTION ELECTRODE AND BIOLOGICAL SIGNAL DETECTION APPARATUS - A biological signal detection electrode includes an electrode element and a plurality of drought-resistant electrolytic solution soaking parts. The electrode element is made of a conductive material and has a surface. The plurality of drought-resistant electrolytic solution soaking parts are placed at predetermined intervals on the surface of the electrode element, are formed to have a thickness that allows contact with a scalp without hair being sandwiched between the electrode element and the scalp, and are soaked in a drought-resistant electrolytic solution including a drought-resistant liquid and a conductive liquid. | 12-29-2011 |
| 20120024700 | SENSOR DEVICE AND MANUFACTURING METHOD - Disclosed is a sensor device ( | 02-02-2012 |
| 20120037506 | METHOD OF MEASURING HEMATOCRIT (Hct), SENSOR USED IN THE METHOD, AND MEASURING DEVICE - The present invention provides a method of electrochemically measuring a hematocrit (Hct) value using a sensor, capable of achieving excellent measurement accuracy and reliability and also provides a sensor used in the method. The method of electrochemically measuring a hematocrit (Hct) value of blood include: providing an electrode system having a working electrode ( | 02-16-2012 |
| 20120043201 | METHOD AND APPARATUS FOR MEASURING SAMPLE REACTION RESULTS ON BIOSENSOR - Disclosed is a method of measuring sample reaction results on a biosensor having a working electrode and other electrodes, including: applying voltage between the working electrode and each of the other electrodes and detecting the amount of current flowing through the working electrode to determine whether or not a sample is injected; applying voltage between the working electrode and one of the other electrodes and re-detecting the amount of current flowing through the working electrode; and acquiring and displaying a concentration value as a sample reaction result corresponding to the amount of detected current. | 02-23-2012 |
| 20120067722 | BIOSENSOR FOR MEASURING BIOMATERIAL - The present invention relates to an apparatus for measuring a biomaterial, comprising: a first substrate having a recess in one side thereof; a second substrate having reference and operating electrodes where a biochemical reaction of a biomaterial occurs, and first and second delivery electrodes delivering electric signals from the reaction to a detector; and reaction reagents fixed at the second substrate causing the reaction with the biomaterial, wherein the first or the second substrate has a tilted surface toward a sample-inlet in a height direction. The second substrate is attached to the first substrate such that a portion of the recess forms the sample-inlet, and the reference and operating electrodes are directed toward the recess. The tilted surface prevents the sample-inlet from being blocked by a finger of the user when introducing the biomaterial through the sample-inlet in the event the used substrate has three-dimensional structures with substantial thickness. | 03-22-2012 |
| 20120073967 | APPARATUS FOR MEASURING BIOMATERIAL AND METHOD FOR MANUFACTURING SAME - The present invention relates to an apparatus for measuring biomaterial and a method for manufacturing thereof. The apparatus of the present invention comprises: a first substrate having a recess in one side thereof; a second substrate having a plurality of reaction electrodes where a biochemical reaction of a biomaterial occurs, and a plurality of delivery electrodes delivering signals from the reaction to a detector; and reaction reagents located in the recess causing the reaction with the biomaterial. The second substrate is attached to the first substrate such that a portion of the recess forms a sample-inlet, the recess cooperates with at least one edge of the second substrate to form at least one vent slit, and the reaction electrodes are directed toward the recess. Such apparatus of the present invention enables air in the capillary to be thoroughly and quickly discharged to the outside with biomaterial-introduction, thereby increasing the speed of the biomaterial-introduction. | 03-29-2012 |
| 20120073968 | SENSOR USED TOGETHER WITH A DETECTOR TO MEASURE BIOMATERIAL, AND APPARATUS USING SAME - The present invention relates to a sensor used together with a detector to measure biomaterial, and to an apparatus using same. A sensor of the present invention comprises: a body portion with a three-dimensional shape, having a biomaterial introduction hole, and attachable and detachable to/from a detector; a sensor portion with a plurality of reaction electrodes formed on one surface thereof, and a plurality of transfer electrodes formed on the other surface thereof; and an analyzer reagent fixed above the reaction electrodes. The sensor portion, together with the body portion, forms a reaction chamber connected to the biomaterial introduction hole, and is attached to the body portion such that the reaction electrodes are oriented toward the reaction chamber. According to the present invention, attachment and detachment is easy, even for the elderly, and the contamination of the sensor can be minimized. | 03-29-2012 |
| 20120080312 | BIOMOLECULES DETECTION METHOD AND BIOMOLECULES DETECTION CHIP - A biomolecules detection chip which detects a detection target biomolecule by an electrochemical response measurement, the chip including: a chamber which is able to accommodate either a standard solution containing an electrochemically reactive agent having a binding capacity to the detection target biomolecule, or a sample solution containing a sample material and the electrochemically reactive agent; a liquid introduction device which introduces the standard solution or the sample solution into the chamber; an electrochemical response measurement device which measures an electrochemical response of either the standard solution or the sample solution accommodated in the chamber; and a liquid ejection device which ejects either the standard solution or the sample solution from the chamber. | 04-05-2012 |
| 20120085642 | POLAROGRAPHIC INSTRUMENT SYSTEM FOR OXYGEN AND HYDROGEN MEASUREMENT - A system for measuring hydrogen (H | 04-12-2012 |
| 20120085643 | ELECTROLYTIC CELL AND METHOD OF USE THEREOF - In one embodiment of the present invention an electrolytic cell is provided comprising a containment vessel; a first electrode; a second electrode; a source of electrical current in electrical communication with the first electrode and the second electrode; an electrolyte in fluid communication with the first electrode and the second electrode; a gas, wherein the gas is formed during electrolysis at or near the first electrode; and a separator; wherein the separator includes an inclined surface to direct flow of the electrolyte and the gas due to a difference between density of the electrolyte and the combined density of the electrolyte and the gas such that the gas substantially flows in a direction distal to the second electrode. | 04-12-2012 |
| 20120103806 | LIQUID SAMPLE MEASUREMENT METHOD AND APPARATUS - A liquid sample measurement apparatus of the present invention is provided with a timer ( | 05-03-2012 |
| 20120145541 | DISEASE DIAGNOSING BIOSENSOR CAPABLE OF PROMPTLY SEPARATING BLOOD CELLS - The present invention relates to a disease diagnosing biosensor capable of promptly separating blood cells, in which a disease can be analyzed further accurately by adding a blood cell separating pad on a front or rear side of a capillary tube and separating the blood cells and plasma within 1 or 2 seconds owing to distribution of hydrophilic and hydrophobic segments. The entire configuration of the biosensor according to the present invention includes a base film; electrodes arranged on a top surface of the base film; a space film covering a top surface of the electrodes; a blood cell separating pad connected to a rear side of the space film; a capillary tube added on a rear top surface of the space film; and a cover film covered on a top surface of the capillary tube and the blood cell separating pad. | 06-14-2012 |
| 20120168306 | INCORPORATING CMOS INTEGRATED CIRCUITS IN THE DESIGN OF AFFINITY-BASED BIOSENSOR SYSTEMS - A biosensor system incorporating CMOS integrated circuits. In one type of biosensor system, the biosensor system includes a silicon substrate. The biosensor system further includes active devices fabricated on the silicon substrate. Additionally, the biosensor system includes a plurality of metal layers stacked on top of the active devices. Furthermore, the biosensor system includes a passivation layer covering a top metal layer, where the passivation layer includes an opening configured to expose the top metal layer, where the opening is used as a sensing electrode. Additionally, the biosensor system includes a plurality of probes attached to the sensing electrode. | 07-05-2012 |
| 20120175252 | SENSING APPARATUS AND METHOD - A method of observing reaction intermediaries during a chemical reaction and comprising detecting an electrical signal output from an ion sensitive field effect transistor exposed to said reaction, and monitoring the detected electrical signal to discriminate discrete fluctuations in the electrical signal, the discrete fluctuations indicating reaction intermediaries occurring during a chemical reaction. | 07-12-2012 |
| 20120193228 | TEST STRIP - A test strip is revealed. The test strip includes a detection area, at least one outer sampling area, and a circuit system. The detection area includes a sampling hole, at least one sampling channel corresponding to the sampling hole, and at least one reaction area in the sampling channel. An inner sampling area is disposed around the sampling hole and an inner sampling opening is on an edge of the inner sampling area for communicating with the sampling channel and the sampling hole. The outer sampling area is located on an outer side of the test strip. The outer sampling area includes an outer sampling opening in communication with the sampling channel. The circuit system is electrically connected to the reaction area. The test strip further includes at least one pressing part located around the sampling hole for pressing against a test area and preventing cross-infection. | 08-02-2012 |
| 20120211361 | Rapid-Read Gated Amperometry Devices - A sensor system, device, and methods for determining the concentration of an analyte in a sample is described. Input signals including multiple duty cycles of sequential excitation pulses and relaxations are input to the sample. One or more signals output from the sample within 300 ms of the input of an excitation pulse may be correlated with the analyte concentration of the sample to improve the accuracy and/or precision of the analysis. Determining the analyte concentration of the sample from these rapidly measured output values may reduce analysis errors arising from the hematocrit effect, mediator background, and other error sources. | 08-23-2012 |
| 20120234677 | BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode | 09-20-2012 |
| 20120241318 | SYSTEM AND METHODS FOR DETERMINING AN ANALYTE CONCENTRATION INCORPORATING A HEMATOCRIT CORRECTION - Methods and devices for determining the concentration of a constituent in a physiological sample are provided. The blood sample is introduced into a test strip with portions of the blood sample being directed to both a first capillary and a second capillary. The first capillary configured to electrochemically determine a concentration of a first analyte in a blood sample by measuring a signal across a set of electrodes. The second capillary is configured to determine a hematocrit value of the blood sample by measuring a signal across a second set of electrodes. | 09-27-2012 |
| 20120247956 | BIOSENSOR STRIP AND MANUFACTURING METHOD THEREOF - The present invention is related to a biosensor strip and a manufacturing method thereof. The biosensor strip comprises an electrode layer that has a first electrode pattern and a second electrode pattern. The two electrode patterns are provided on a base by different manufacturing methods. The first electrode pattern is made by a first electrically conductive material that may consist of precious metal and the second electrode pattern is made by a second electrically conductive material that may not consist of precious metal. | 10-04-2012 |
| 20120305394 | BIOSENSOR HAVING IDENTIFICATION INFORMATION AND APPARATUS FOR READING IDENTIFICATION INFORMATION OF BIOSENSOR - An apparatus for reading identification information of a biosensor is provided, including a biosensor sensing unit detecting the biosensor, a light-emitting unit emitting light on an identification information recording unit when the biosensor sensing unit detects the biosensor, the identification information recording unit having the identification information of the biosensor recorded thereon, a light-receiving unit that receives the light emitted from the light-emitting unit, and reflected or refracted by or passing through the identification information recording section, and an identification information reading unit analyzing the light received by the light-receiving unit and reading the identification information of the biosensor. | 12-06-2012 |
| 20120312684 | Multiple-Biosensor Article - An article suitable for conducting one or more assays with an apparatus, e.g., a meter, for determining the presence or concentration of an analyte in a sample of biological fluid. The article contains a plurality of biosensors arranged in such a manner that each of the biosensors can be utilized before the article must be removed from the apparatus. | 12-13-2012 |
| 20120325657 | SENSOR DEVICE - A sensor device includes a substrate and a sensor chip held on the substrate. The substrate includes a flow channel. The sensor chip includes a plate. The plate includes a first surface and a second surface opposite to the first surface. A plurality of through holes each penetrates through the first surface and the second surface. A direction of a line segment connecting centers of any two adjacent through holes among the plurality of through holes is neither parallel nor perpendicular to the center line of the flow channel. | 12-27-2012 |
| 20130008785 | METHODS FOR THE DETECTION AND DIAGNOSIS OF MALARIA USING AN ELECTROCHEMICAL SENSOR - Disclosed are apparatuses for detecting hemoglobin in patient samples. The apparatuses include a primary electrode and a reference electrode. The apparatus is configured to measure current or voltage generated between the primary electrode and the reference electrode in response a redox reaction catalyzed by hemoglobin. The apparatuses can detect a variety of hemoglobins, including dimeric hemoglobin associated with malaria. Also disclosed are biosensor systems including the apparatuses and methods of using the biosensor systems. | 01-10-2013 |
| 20130008786 | SENSOR CHIP AND STORAGE METHOD THEREOF - A sensor chip is a sensor device for measuring a property of a substance by adsorbing the substance on a surface of the sensor chip. The sensor chip includes a diaphragm having a first surface, a second surface, and at least one through hole penetrating from the first surface to the second surface. At least a part of the first surface, the second surface, and an inner wall surface of the through hole is covered with a noncrystalline solid layer including SiOX as a main component, in which substance X is an element having higher electronegativity than that of silicon. | 01-10-2013 |
| 20130015062 | ELECTRODE FOR MEASURING GLYCOPROTEIN AND PREPARATION METHOD THEREOFAANM Ku; Yun HeeAACI SeoulAACO KRAAGP Ku; Yun Hee Seoul KRAANM Yang; Yong JuAACI SeoulAACO KRAAGP Yang; Yong Ju Seoul KRAANM Park; Yoo MinAACI Suwon-siAACO KRAAGP Park; Yoo Min Suwon-si KRAANM Song; Seung YeonAACI Suwon-siAACO KRAAGP Song; Seung Yeon Suwon-si KRAANM Han; Yong DukAACI Suwon-siAACO KRAAGP Han; Yong Duk Suwon-si KRAANM Kim; Moo SubAACI SeoulAACO KRAAGP Kim; Moo Sub Seoul KRAANM Yoon; Hyun ChulAACI Suwon-siAACO KRAAGP Yoon; Hyun Chul Suwon-si KR - Disclosed herein are an electrode for measuring glycoprotein and a preparation method thereof. In the electrode, cystamine is bound to the electrode surface, and boronic acid is conjugated to the cystamine. Thus, an increased amount of boronic acid can be bound to the electrode surface, so that the amount of glycoprotein can be more accurately measured using the electrode. | 01-17-2013 |
| 20130092535 | LIQUID-DEVELOPING SHEET - This invention is a liquid-developing sheet comprising a liquid-accepting layer at least on one surface of a substrate, wherein said liquid-accepting layer contains a binder and a block copolymer comprising blocks of ethylene oxide units and blocks of alkylene oxide units with 3 or more carbon atoms. This invention can provide a liquid-developing sheet for a biosensor, which shows stable liquid developability even at high temperature and high humidity and is good in the adhesion between the liquid-accepting layer and the substrate. If the liquid-developing sheet of this invention is used, the accuracy of measurement by the biosensor can be enhanced. | 04-18-2013 |
| 20130098762 | Patch-Clamp Providing On-Chip Thermal Gradient - A patch clamp system providing precise and rapid temperature control of constrained cell membranes employs the thermal element attached to the substrate of the patch clamp. In one embodiment, the thermal element is a Peltier device fabricated on a silicon membrane wafer bonded to the substrate of the patch clamp. | 04-25-2013 |
| 20130112557 | Handheld Blood Glucose Monitoring Device With Messaging Capability - A patient monitoring network pertaining to blood glucose and other analyte measurements includes wireless blood glucose or other analyte measuring devices and a networked computer or server. Each monitoring device is associated with a patient and is configured to measure the glucose level or other analyte from a given blood sample via inserted test strips, transmit the measurements to the networked computer, and display received messages. The blood glucose monitoring device includes means for substantially reducing factors that could affect the glucose measurement such as thermal and RF interference. | 05-09-2013 |
| 20130140176 | ELECTRODE ARRANGEMENTS FOR BIOSENSORS - The present invention relates to a biosensor. The biosensor includes a support substrate, electrodes positioned on the support substrate, a spacer substrate positioned on the support substrate, and a cover positioned on the spacer substrate. The cover cooperates with the support substrate to define a capillary channel. The electrodes include at least one working electrode defining a working electrode area in the capillary channel. The working electrode is configured to minimize variation in the working electrode area in the capillary channel due to variations in the spacer substrate placement relative to the working electrode. | 06-06-2013 |
| 20130161189 | ORNAMENT FOR PLANT - The ornament for fresh flower has, for example, the first decorative part encloses and maintains on the stem side of fresh flower, the second decorative part of the image of a doll's head and the third decorative part of the image of the doll's body. The first decorative part, the second decorative part and the third decorative part are packed and sold in bags separately (Individually). | 06-27-2013 |
| 20130186754 | BIOSENSOR CAPACITOR - A biosensor capacitor, including a dielectric layer; a first metal layer in the dielectric layer; a passivation layer over the dielectric layer and the first metal layer; an isolation layer over the passivation layer; a probe DNA electrode connected to the first metal layer; a counter electrode connected to the first metal layer wherein the counter electrode forms an enclosure around the probe DNA electrode; and a bond pad connected to the first metal layer. | 07-25-2013 |
| 20130206595 | BIOSENSOR WITH THREE-DIMENSIONAL STRUCTURE AND MANUFACTURING METHOD THEREOF - The present invention relates to a biosensor which is formed with a three-dimensional structure using 3D molded interconnect device (MID) technology and a manufacturing method thereof. The present invention provides a biosensor in which reactive electrodes and signal transfer parts are formed in a three-dimensional structure on a surface of a polymer using the 3D MID technology, and a manufacturing method thereof. | 08-15-2013 |
| 20130228461 | ELECTROCHEMICAL BIOSENSOR ELECTRODE STRIP AND A FABRICATION METHOD THEREOF COMPRISING A TITANIUM METAL LAYER ON A CARBON LAYER AS THE ELECTRODE MATERIAL - The present invention relates to an electrochemical biosensor electrode strip fabricated by forming a carbon layer on a non-conductive substrate made of polymer material, forming a metal layer containing titanium thereon, and performing patterning. | 09-05-2013 |
| 20130256131 | BIOSENSOR - The present invention disclosed a biosensor apparatus comprising a substrate on which a reaction region is defined, a fluid channel defining a path to the reaction region, and a venting means communicably coupled with the fluid channel and opening exterior of the biosensor apparatus at a perimeter side of the biosensor apparatus. The present invention allows air to exit the fluid channel through perimeter sides of the biosensor apparatus without adding significant manufacturing complexity. | 10-03-2013 |
| 20130292246 | Quality Assurance System and Method for Point-of-Care Testing - An improved quality assurance system and method for point-of-care testing are disclosed. The present invention provides quality assurance for laboratory quality tests performed by a blood analysis system or the like at the point of patient care without the need for running liquid-based quality control materials on the analysis system. Quality assurance of a quantitative physiological sample test system is performed without using a quality control sample by monitoring the thermal and temporal stress of a component used with the test system. Alert information is generated that indicates that the component has failed quality assurance when the thermal and temporal stress exceeds a predetermined thermal-temporal stress threshold. Alternatively, the present invention provides quality assurance for laboratory quality tests performed by a blood analysis system or the like at the point of patient care by minimizing the need for running liquid-based quality control materials on the analysis system. | 11-07-2013 |
| 20130306472 | BIOSENSOR - A biosensor is capable of preventing a sample from flowing out of the air hole to the outside with superior accuracy. The biosensor includes: a first substrate having an air hole; and a second substrate, the first and second substrates being laminated on each other, wherein the biosensor has a sample flow path between the first and second substrates, in a sample flow direction in the flow path, an upstream end of the flow path is in communication with a sample introduction port, and a downstream end of the flow path is in communication with the air hole, an upper surface of the flow path is formed of a surface of the first substrate facing the second substrate, and a region on the introduction port side of the upper surface of the flow path is a hydrophilic region, and a region on the air hole side of the upper surface of the flow path is a water-repellent region. | 11-21-2013 |
| 20130306473 | METHOD FOR PRODUCING A DEVICE FOR DETECTING AN ANALYTE AND DEVICE AND THE USE THEREOF - A method for producing a device for detecting an analyze, comprises the following steps: a) disposing a first conductor having an electrode function on an insulating substrate; b) disposing a first passivation layer on the conductor; c) opening the passivation layer in a locally delimited manner, so that the conductor is exposed in a locally delimited manner; d) disposing a sacrificial layer on the conductor in the opening; g) disposing a second passivation layer on the electrode and on the second conductor; h) opening the second passivation layer and the electrode so that the sacrificial layer is exposed; and i) removing the sacrificial layer. Also comprising an appropriately designed device and the use thereof. | 11-21-2013 |
| 20130306474 | BIOLOGICAL SAMPLE MEASURING DEVICE - A biological sample measuring device in which a deposited biological sample is introduced into a capillary, a biological sample measuring sensor in which a reagent and the biological sample provided is mounted, and the biological sample is measured. The biological sample measuring device comprises a mounting portion, a voltage application section, and a detection component. The biological sample measuring sensor is mounted to the mounting portion. The voltage application section applies a measurement voltage to a plurality of electrodes disposed along the capillary. The detection component eliminates the effect of seepage of the biological sample by pass-around at the end of the capillary, or the effect whereby the plasma component seeps into the reagent, and detects the degree to which the biological sample is introduced into the capillary, based on the output result for the voltage applied by the voltage application section to the electrodes. | 11-21-2013 |
| 20130334040 | Methods and Systems For Detecting The Hydration Of Sensors - A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes. | 12-19-2013 |
| 20130334041 | DEVICE FOR MEASURING BIOLOGICAL SAMPLE - The objective of the invention is to enhance measurement accuracy in a device for measuring a biological sample. To attain this objective, the invention is provided with a main case ( | 12-19-2013 |
| 20130341185 | Micro-Stimulation and Data Acquisition From Biological Cells - The present invention relates to a method for fabricating a semiconductor device for stimulation and/or data recording of biological material to a such semiconductor device. The method comprises providing a semiconductor substrate comprising a first insulating layer; providing a patterned conductive layer on top of the first insulating layer; depositing and patterning a second insulating layer atop the patterned conductive layer; growing carbon nano-sheets atop the second insulating layer; and defining carbon nano-sheet electrode areas on the second insulating layer by etching away the carbon nano-sheets outside of the carbon nano-sheet electrode areas. | 12-26-2013 |
| 20140001041 | BIOSENSOR | 01-02-2014 |
| 20140014508 | LIQUID SAMPLE MEASURING DEVICE - The present liquid sample measuring device comprises a device body on which a biosensor is detachably mounted, a liquid biological sample being dispensed in drops on the biosensor; a measuring section that measures bioinformation from the liquid biological sample; a motion measuring section that measures motion information of the device body; a motion assessment section that assesses the degree of motion of the device body on the basis of the motion information of the device body measured by the motion measuring section; and a measurement controller that adjusts the measurement time for measuring the bioinformation on the basis of the assessment result of the motion assessment section. | 01-16-2014 |
| 20140021045 | APPARATUS AND METHOD FOR IMPROVED MEASUREMENTS OF A MONITORING DEVICE - Methods and devices for improving measurements of test meter, and in particular for detecting a presence of an electrochemical sensor or strip in the test meter and a start time of an electrochemical reaction, are provided. In one exemplary embodiment of an electrochemical system includes an electrochemical sensor, a test meter, and a circuit. The circuit is configured to form an electrical connection with the electrochemical sensor such that the circuit can detect three distinct voltage ranges. The voltage ranges can be indicative of an absence of the electrochemical sensor, a presence of the sensor that is devoid of a sample, and a presence of the sensor with a sample. Test meters, methods for detecting when a sample starts to fill an electrochemical sensor for establishing when a reaction starts, and circuits for use with electrochemical strips, are also provided. | 01-23-2014 |
| 20140034492 | Fuel Cell Housing for Use in an Alcohol Breath Tester - An alcohol fuel cell sensor and the resultant alcohol breath tester assembly. The disclosed housing creates an alcohol breath tester assembly that protects the electrode sensor from liquid ingress, maximizes the sample contact with the platinum electrode surface, and provides a smooth path facilitating laminar flow of the sample through the sensor. This, in turn, provides good flushing of the volume without creating eddies or other turbulence. Additionally, the housing can utilize a vapor barrier layer in the assembly and restricts the layer from touching the electrode surface. | 02-06-2014 |
| 20140034493 | METHODS AND SYSTEMS FOR DETECTING THE HYDRATION OF SENSORS - A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes. | 02-06-2014 |
| 20140042024 | ELECTRICAL PATTERNS FOR BIOSENSOR AND METHOD OF MAKING - The present invention provides an inventive biosensor that includes multiple regions in which the electrical pattern is formed from different electrically conductive materials. The present invention also provides an inventive method for mass producing biosensors as just described. In one embodiment of this method, first and second different electrically conductive materials are deposited side by side on a portion of an electrically insulating base material, and a plurality of electrical patterns is formed on the portion of the base material. Each electrical pattern includes a first region formed from the first electrically conductive material electrically connected to a second region formed from the second electrically conductive material. The electrically conductive materials can be deposited as layers on the base material and portions of the layers can be removed to form the electrical patterns, or, the electrical patterns can be formed by transferring the conductive material in the shape of the electrical pattern directly to the base material, such as by a laser direct transfer technique. | 02-13-2014 |
| 20140054169 | STACKABLE ELECTROCHEMICAL ANALYTE SENSORS, SYSTEMS AND METHODS INCLUDING SAME - In some aspects, an analyte sensor is provided for detecting an analyte concentration level in a bio-fluid sample. The analyte sensor has a base with first and second ends, a concave recess in the first end, a second end receiving surface, and a sidewall extending between the ends. An electrode may be provided on the receiving surface with an electrochemically-active region coupled to the electrode. A conductor in electrical contact with the electrode may extend along the sidewall and may be adapted to be in electrical contact with a first contact of an analyte meter. Manufacturing methods and systems utilizing and dispensing the analyte sensors are provided, as are numerous other aspects. | 02-27-2014 |
| 20140054170 | BIOSENSOR DEVICE - A biosensor device which is possible to be downsized and potable, is free of the problem of solution outflow, and enables detection accurately and stably is realized. A biosensor device ( | 02-27-2014 |
| 20140061042 | ALCOHOL DETECTION DEVICES, APPARATUSES, METHODS, AND COMPUTER PROGRAM PRODUCTS FOR USE IN COMMUNICATION WITH A MOBILE APPLICATION ON A MOBILE DEVICE - According to various embodiments, an alcohol detection apparatus is provided for use in conjunction with a mobile application resident on a mobile device. The apparatus comprises: a memory and one or more processors. The one or more processors are configured to: determine whether at least one communication pathway exists between the apparatus and the mobile application resident on the mobile device; responsive to a determination that at least one communication pathway exists, generate an indication that the apparatus is ready to facilitate conducting of at least one blood alcohol content (BAC) level test therewith; capture test data associated with the conduct of at least one BAC level test; and convert the test data into formatted data, the formatted data being suitable for transmission from the apparatus and to the mobile application via the at least one communication pathway. Associated computer-implemented methods and non-transitory computer program products are also provided. | 03-06-2014 |
| 20140061043 | ALCOHOL-MEASURING DEVICE WITH FAST OPERATIONAL READINESS - An alcohol-measuring device includes a mouthpiece ( | 03-06-2014 |
| 20140061044 | NON-ENZYMATIC GLUCOSE SENSOR - A non-enzymatic glucose sensor and method for fabricating the sensor are disclosed. The glucose sensor contains at least one non-enzymatic electrode configured to catalyze the electro-oxidation of glucose in preference to other bio-molecules. The surface of the electrode comprises CuO nanoparticles. The sensor shows sensitivity and selectivity exceeding enzyme based devices presently in use. | 03-06-2014 |
| 20140102894 | TEST STRIP FOR MEASURING BIOLOGICAL FLUID - The invention provides a test strip for measuring biological fluid. The test strip comprises an insulating sheet, a circuit layer, a sensing reagent layer, an intermediate layer and a cover. The circuit layer is disposed on the insulating sheet, the circuit layer connecting to an electrode section. The sensing reagent layer is disposed on the electrode section. The intermediate layer is provided to cover the insulating sheet and the circuit layer, the intermediate layer having an opening to expose the sensing reagent layer and the electrode section. The cover is provided to cover the intermediate layer and the insulating sheet and expose part of the circuit layer, the cover having two holes corresponding to the opening. The circuit layer is provided in an adhering manner to enhance the stability of resistance and the test accuracy. | 04-17-2014 |
| 20140102895 | SENSOR AND SENSOR SYSTEM EQUIPPED WITH SAME - This sensor has a diverter, such as a convex portion ( | 04-17-2014 |
| 20140116879 | METHOD FOR MEASURING HEMATOCRIT VALUE OF BLOOD SAMPLE, METHOD FOR MEASURING CONCENTRATION OF ANALYTE IN BLOOD SAMPLE, SENSOR CHIP AND SENSOR UNIT - Provided is a sensor chip for electrochemically measuring a concentration of an analyte in a blood sample. In one embodiment of the sensor, the sensor chip includes a substrate, and a preliminary measurement analyzer and a hematocrit value analyzer disposed on the substrate. The preliminary measurement analyzer includes a preliminary working electrode and a preliminary counter electrode. The hematocrit value analyzer includes a working electrode and a counter electrode. An oxidant of a redox substance is disposed on the preliminary measurement analyzer and the counter electrode. A reductant of a redox substance is disposed on the working electrode. | 05-01-2014 |
| 20140151221 | BIOSENSOR MODULE COMPRISING A BIOCOMPATIBLE ELECTRODE - A method of manufacturing a module for a biosensor is disclosed. The method includes providing a substrate. The substrate includes a trench and a bond pad. The trench is filled with an electrically conductive material and the bond pad is arranged within the substrate. The method also includes removing a part of the electrically conductive material from the trench such that a recess is formed in a surface of the substrate, forming a biocompatible electrode in the recess, and removing a part of the substrate such that the bond pad is accessible through the surface of the substrate. | 06-05-2014 |
| 20140151222 | Measuring device and methods for use therewith - The ability to switch at will between amperometric measurements and potentiometric measurements provides great flexibility in performing analyses of unknowns. Apparatus and methods can provide such switching to collect data from an electrochemical cell. The cell may contain a reagent disposed to measure glucose in human blood. | 06-05-2014 |
| 20140158533 | Biosensors and Methods of Preparing Same - A biosensor strip having a low profile for reducing the volume of liquid sample needed to perform an assay. In one embodiment, the biosensor strip includes an electrode support; an electrode arrangement on the electrode support; a cover; a sample chamber; and an incompressible element placed between the cover and the electrode support, the incompressible element providing an opening in at least one side or in the distal end of the sample chamber to provide at least one vent in the sample chamber. In another embodiment, the biosensor strip has an electrode support; an electrode arrangement on the electrode support; a cover; and a sample chamber, the cover having a plurality of openings formed therein, at least one of the openings in register with the sample chamber. The invention further includes methods for preparing such a biosensor strips in a continuous manner. | 06-12-2014 |
| 20140190823 | BIOSENSOR - A biosensor is provided. The biosensor includes a base plate including a detector configured to detect a sample through an electrode, an insulation layer disposed on a top surface of the base plate, a top plate mounted over the base plate and including a sample inlet that introduces the sample onto the detector, and a spacer interposed between the top plate and the insulation layer and forming a chamber. | 07-10-2014 |
| 20140238854 | ELECTRODE STRIP AND SENSOR STRIP AND SYSTEM THEREOF - The present disclosure relates to an electrode strip, a sensor strip and a system thereof. The electrode strip includes a substrate, an electrode layer, an insulation layer and a cover. The electrode layer is disposed on the substrate. The electrode layer includes a first electrode set and a second electrode set. The insulation layer includes a groove, a first protrusion and a second protrusion. The first protrusion and the second protrusion divide the groove into two reactive areas such as a first reactive area and a second reactive area. The cover includes a vent-hole connecting to the groove, and the cover is disposed on the insulation layer. | 08-28-2014 |
| 20140262773 | ELECTRODE CONFIGURATION FOR A BIOSENSOR - A biosensor including a capillary chamber having an inner boundary, a working electrode including an effective working electrode portion positioned within the capillary chamber, and a counter electrode including an effective counter electrode portion positioned within the capillary chamber, and with the working and counter electrodes each having a neck that constitutes the sole portion of the electrodes that extends across the inner boundary and out of the capillary chamber. In one embodiment, the effective working electrode portion defines an average working electrode width, and the working electrode neck defines a working electrode neck width that is reduced relative to the average working electrode width. In another embodiment, a ratio between the area of the effective working electrode portion exposed to the capillary chamber and the area of the effective counter electrode portion exposed to the capillary chamber is substantially constant as a position of the inner boundary of the capillary chamber is varied along a length of the working and counter electrode necks. | 09-18-2014 |
| 20140262774 | ELECTROLYTE SENSOR AND METHOD FOR PRODUCING THEREOF - Provided is an electrolyte sensor that uses conductive elastomer electrodes. Examples of the intended analytes for sensor use include those found in urine, saliva, blood, feces, and spinal fluid, although other analytes exist for electrolyte detection. Conductive elastomer trace electrodes are separated by a channel or gap which can be bridged by an electrolyte and thereby complete an electrical circuit to an alarm or other circuitry. Channel or gap distances vary the level of electrical resistance associated with detecting certain analytes. | 09-18-2014 |
| 20140311904 | BIOSENSOR FOR POINT-OF-CARE DIAGNOSTIC AND ON-SITE MEASUREMENTS - Disclosed herein is a biosensor for detection of a target substance in a sample with impedance spectroscopy, the biosensor comprising 1) a first non-conducting substrate comprising a primary substrate surface; 2) a conducting polymer electrode layer comprising one or more conducting polymers layers, the conducting polymer electrode layer comprising a primary electrode surface and a secondary electrode surface, wherein the secondary electrode surface covers part of the primary substrate surface; 3) a probe layer bonded to part of the primary electrode surface; and 4) a second non-conducting substrate comprising a secondary substrate surface, wherein the secondary substrate surface of the second substrate and the primary substrate surface of the first substrate are interconnected such that the electrode layer and the probe layer are confined within an area defined by the first substrate and the second substrate; wherein the electrode layer comprises at least a first electrode pair, the first electrode pair comprising a primary electrode and a secondary electrode, where the probe layer is bonded to the primary electrode and the secondary electrode of the at least first electrode pair, the probe layer being adapted for selectively binding of the target substance. | 10-23-2014 |
| 20140318958 | INTEGRATED ELECTRO-ANALYTICAL BIOSENSOR ARRAY - A biosensor pixel for measuring current that flows through the electrode surface in response to electrochemical interactions and a biosensor array architecture that includes such biosensor pixels. The biosensor pixel includes an electrode transducer configured to measure a current generated by electrochemical interactions occurring at a recognition layer placed directly on top of it in response to an electrical voltage placed across an electrode transducer-electrolyte interface. The biosensor pixel further includes a trans-impedance amplifier connected to the electrode transducer, where the trans-impedance amplifier is configured to convert the current into a voltage signal as the electrochemical interactions occur. Additionally, the biosensor pixel includes a 1-bit comparator coupled to the trans-impedance amplifier and a 1-bit digital-to-analog converter coupled to the 1-bit comparator, where the 1-bit digital-to-analog converter injects different levels of charge into an input of the trans-impedance amplifier at each cycle based on an output of the 1-bit comparator. | 10-30-2014 |
| 20140326598 | MODULE-TYPE BIOSENSOR - Provided is a module type biosensor which is easily coupled with and separated from a detector. The module type biosensor includes a reaction substrate which reacts with an introduced sample and generates a reaction signal, a first structure body which is formed as a pole-shaped figure having an opening formed at one base side thereof and in which a detector performing an analysis of the introduced sample based on the reaction signal generated from the reaction substrate is inserted and coupled into an opened base side having the opening so as to be in contact with the reaction substrate, and the reaction substrate is coupled to a blocked base side of a position corresponding to an opened base side, a second structure body which is coupled to the blocked base side and forms a reaction chamber generating the reaction signal when being coupled to the blocked base side, and a housing which is formed to enclose outer surfaces of the first structure body and the second structure body and slides along the outer surfaces of the first structure body and the second structure body. | 11-06-2014 |
| 20140332377 | Sample-Retainable Biosensor Test Strip - A biosensor test strip includes: a first working electrode and a second working electrode formed on a base plate, having the second working electrode circumferentially surrounding the first working electrode to define a reaction pool within the second working electrode having a biological reagent provided in the reaction pool. Upon feeding a liquid sample of a user or patient into the reaction pool, the liquid sample will be well retained in the reaction pool to be reacted with the reagent to produce a signal which is then converted to be a readable data as displayed on a measurement apparatus or meter. | 11-13-2014 |
| 20140353152 | BIOSENSOR AND METHOD FOR MANUFACTRUING SAME - Disclosed is a method for manufacturing a biosensor comprising (a) forming an insulating layer in an electrode region; (b) coating the first photoresist layer on the insulating layer; (c) performing the firs exposing process on the first electrode region through the first photomask; (d) removing unexposed area of the first photoresist layer except for the first electrode region using development; (e) coating the second photoresist layer on the first electrode region and the insulating layer after the step (d); (f) performing the second exposing process on the second electrode regions through the second photomask; (g) performing the third exposing process on the top portion of the second photoresist layer through a photomask with open areas in the shape of micro-sized wires connecting the second electrode regions; (h) removing the second photoresist layer except for the portions exposed in the steps (c), (f) and (g) using development. | 12-04-2014 |
| 20140367255 | INTERDIGITATED ARRAY AND METHOD OF MANUFACTURE - An automated feed manufacturing product is disclosed. The automated feed manufacturing product is provided with a flexible substrate having a plurality of card zones with the card zones defining sensing areas with sensor units formed within the sensing areas. The sensor units have a first electrode having first fingers, and a second electrode having second fingers and with the first fingers interleaved with the second fingers and with the first fingers spaced away from the second fingers. The sensor units also comprising biomolecule receptors on the flexible web between the first electrode and the second electrode such that a physical property of the first electrode relative to the second electrode is effected upon one or more of the biomolecule receptors binding to a biomolecule. The automated feed manufacturing product can be formed as a continuous web, or discrete sheets formed using a sheet feeder that picks up and processes the discrete sheets. | 12-18-2014 |
| 20140367256 | MEDICAL MEASURING DEVICE AND MEDICAL MEASURING SYSTEM - In a housing configured to mount thereon a biosensor in an attachable and detachable manner in which the biosensor is configured to have a liquid sample of a biological object deposited thereon, the medial measuring device includes a measuring component operable to measure biological information from the liquid sample of the biological object, a recording component operable to store a result measured by the measuring component, and an information protection component operable to determine an access limitation to personal information data stored in the recording component. With this configuration of the device, it is possible to properly protect personal information stored in the device. | 12-18-2014 |
| 20150008122 | PATIENT SERUM/PLASMA SAMPLE RESISTIVITY FOR ELECTROLYTE RESULT VERIFICATION - Verification of patient sample electrolyte results using a separate quantitative measurement of sample resistivity. Sample resistivity may be used to measure small differences in resistivity of one sample to the next, and in comparison to a standard solution, in order to verify the results of sample electrolyte measurements being measured at the same time by, for example, individual ion selective electrodes (ISE) in a clinical analyzer. Providing a separate or secondary quantitative means for verification of the measured results of sample electrolytes using sample resistivity solves the problem of electrolyte result variability in sample electrolyte measurements. The process may compare a measured sample resistivity to an expected resistivity value as a verification of the accuracy of individual electrolyte results. Suspect samples—e.g., where the electrolyte resistivity results do not fit the expected resistivity—may be flagged. This separate verification step provides added confidence in the measured electrolyte results and can identify when problems occur or interferences are present in real time. | 01-08-2015 |
| 20150014159 | BIOLOGICAL INFORMATION MEASUREMENT DEVICE - An engagement component that engages with the rear part of a sensor mounted to a sensor connector, and a manipulation body that moves this engagement component to a sensor insertion opening side are provided. In addition, there are provided a manipulation rod that is engaged at one end with the manipulation body and whose other end is pulled out of a main body case through a through-hole provided to the main body case, and a manipulation component that is linked to the other end side of this manipulation rod. The device further comprises an annular wall that is provided outside the main body case and around a through-hole, and a metal slide bearing that covers this annular wall, and a resin sliding member that is slid with respect to a metal slide bearing is provided on the metal slide bearing side of the manipulation component. | 01-15-2015 |
| 20150014160 | APPARATUS FOR SUPPORTING AN ARRAY OF LAYERS OF AMPHIPHILIC MOLECULES AND METHOD OF FORMING AN ARRAY OF LAYERS OF AMPHIPHILIC MOLECULES - An apparatus for supporting an array of layers of amphiphilic molecules, the apparatus comprising: a body ( | 01-15-2015 |
| 20150021178 | BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode | 01-22-2015 |
| 20150027884 | Method of Compressing Fuel Cell Electrodes, Resultant Fuel Cell, and a Housing for the Fuel Cell Which Utilizes Electrolyte Reservoirs - An electrode element and fuel cell and a new method of manufacturing a fuel cell, particularly for use in a breath alcohol detector. This new element includes a reservoir for extra electrolyte that can allow near perfect capillary action to keep the electrode substrate full of electrolyte for long periods of time, increasing its useful life, especially under harsh conditions. Further, the capillary action need not work through a layer of electrode and can be integrally formed with the electrode element to eliminate or reduce loss due to connective surfaces. Wire connections and arrangements are generally of no concern in this design as the reservoirs for electrolyte connect directly to the substrate and electrolyte does not need to pass through an electrode. | 01-29-2015 |
| 20150041315 | MICROCHIP STRUCTURE AND TREATMENTS FOR ELECTROCHEMICAL DETECTION - Disclosed herein are processes and devices for use in the electrochemical detection of a target in a sample. For example, silicon or glass surfaces are treated with silanes functionalized with various side chains to tune the surface wetting characteristics. | 02-12-2015 |
| 20150047976 | ANALYTICAL TEST STRIP HAVING CANTILEVERED CONTACTS - A biosensor for use as an analytical test strip is formed as a main body having a first electrode facing in a first direction, a second electrode facing in a second direction, a pair of spacers disposed between the first and second electrodes, wherein the first electrode extends from the main body of the biosensor at a first angle and the second electrode extends from the main body at a second angle transverse to the first angle. | 02-19-2015 |
| 20150047977 | AUTOMATIC CODING DEVICE, BIOSENSOR WITH SAME AND MANUFACTURING METHOD THEREFOR - The present invention provides an automatic encoding device including a first electrode, a second electrode, and a third electrode. The first electrode and the second electrode are connected through a connecting point, so that an electric parameter between the first electrode and the second electrode changes according to a parameter needing to be corrected. The present invention further provides a method for applying the automatic encoding device to various biosensors and a method for manufacturing the automatic encoding device. Positions and the number of contacts for connecting the automatic encoding device and a detection system are fixed. Therefore, connection sites on the detection system are effectively utilized. On the other hand, the automatic encoding device in the present invention can provide different parameter information by only changing the positions of the connecting points on the electrodes, the process is simple and stable, and the probability of human errors is reduced. | 02-19-2015 |
| 20150053556 | BIOCHIP MICRO-POROUS SENSOR - An improved biochip micro-porous sensor includes a substrate, in which a micro-pore, sensing electrodes and micro-channels are disposed. At least one transition channel is disposed at one side of the micro-pore, and at least one reservoir is connected with the micro-channel. At least two sensing electrodes are disposed at left side and right side of the micro-pore, respectively. A raised object is disposed at the transition channel, descending from the micro-pore down to a bottom surface of the micro-channel, such that the micro-channels and the reservoir have a depth greater than a depth of the micro-pore. | 02-26-2015 |
| 20150053557 | BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode | 02-26-2015 |
| 20150053558 | BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode | 02-26-2015 |
| 20150060270 | BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode | 03-05-2015 |
| 20150060271 | BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode | 03-05-2015 |
| 20150068892 | BIOSENSOR, BIOSENSOR CHIP AND BIOSENSOR DEVICE - A biosensor includes a working electrode | 03-12-2015 |
| 20150083589 | BIO SENSING DEVICE - The present invention relates to a bio sensing device having a reaction part and a measuring device which are integrated therein. The bio sensing device includes: a main substrate, a reaction part, a signal processing part, a screen display part, and a housing. The reaction part includes a reaction reagent to react in an oxidation-reduction reaction with an analysis target material and a reaction electrode to generate an analogue electrical signal by causing the oxidation-reduction reaction, and is located at an end of the main substrate. The signal processing part is located on a first side of the main substrate and processes the analogue electrical signal. The screen display part displays a processing result of the signal processing part. The housing houses the main substrate. The screen display part is three-dimensionally disposed over the signal processing part, and a space for mounting a lancet is formed in the housing. | 03-26-2015 |
| 20150090588 | SYSTEMS AND METHODS FOR BIOLOGICAL ION CHANNEL INTERFACES - Method for interfacing an integrated circuit with a biological ion channel, the integrated circuit being at least partially disposed within an electrolytic solution and including an amplifier and one or more electrodes on a surface thereof, includes forming one or more microwells proximate the one or more electrodes, applying a lipid membrane over the integrated circuit proximate the microwells, and placing a further electrode in the electrolytic solution proximate the lipid membrane on a side opposite the integrated circuit. A biological ion channel interface is also provided. | 04-02-2015 |
| 20150107993 | METHODS AND APPARATUSES FOR EVALUATING WATER POLLUTION - There are provided methods and apparatuses for evaluating water pollution. The apparatus comprises at least one light source for exciting or causing activity of at least one type of microorganism or biological material; at least one photodetector for detecting a level of fluorescent light; and a chip disposed between the at least one light source and the detector, the chip comprising at least one microfluidic channel disposed for being exposed to light from the at least one light source and dimensioned for receiving a composition comprising the at least one type of microorganism or biological material and a water sample to be evaluated. | 04-23-2015 |
| 20150293049 | Sensing Device and Method of Fabricating the Same - The present invention provides a sensing device. The sensing device at least comprises a substrate, a layer of gold material and a layer of diamond nanowires, in which the layer of gold material is disposed on the substrate and the layer of diamond nanowires is disposed on the layer of gold material. A method of fabricating the abovementioned sensing device is also disclosed in the present invention. | 10-15-2015 |
| 20150316500 | DEVICE INCLUDING BIOSENSOR AND HOLDER - A device utilising biosensors to enable rapid electrochemical sensing of one or more analytes in a container. The device comprises a holder which incorporates at least one reference electrode and at least one sensing electrode. The sensing electrode comprising an electrically conductive substrate which is coated in a first layer of a suitable electron acceptor and subsequently with a second layer incorporating a biorecognition molecule adsorbed or within a suitable electropolymer matrix or carrier. | 11-05-2015 |
| 20150346184 | Analyte Sensor Ports - The present disclosure provides a contamination resistant sensor port which includes one or more sealing members positioned so as to limit and/or prevent internal contamination of the sensor port with fluids and/or particles present in the environment outside the sensor port. | 12-03-2015 |
| 20150377817 | DETECTOR FOR DETECTING URINE - A detector for detecting urine includes a first electrode, a second electrode and a processing unit. The first electrode and the second electrode are disposed opposite each other, and are soaked in urine under detection. An electrical path is formed among the first electrode, the urine and the second electrode. The processing unit, electrically connected to the first electrode and the second electrode, measures a plurality of ions in the urine transmitted in the electrical path to obtain a conductivity of the urine and to accordingly determine a kidney function status associated with the urine. Compared to a conventional urine test strip, the invention not only provides a precise detection value but also offers advantages of repeatable usage. | 12-31-2015 |
| 20150377818 | BIOSENSOR INCORPORATING PROTEIN-IMMOBILIZED MEMBRANE AND METHOD OF IMMOBILIZING PROTEIN IN BIOSENSOR - The present invention relates to a protein-immobilized membrane ( | 12-31-2015 |
| 20160011139 | APPARATUS FOR READING IDENTIFICATION INFORMATION OF BIOSENSOR | 01-14-2016 |
| 20160047776 | BIOLOGICAL SAMPLE MEASURING DEVICE - A biological sample measuring device in which a deposited biological sample is introduced into a capillary, a biological sample measuring sensor in which a reagent and the biological sample provided is mounted, and the biological sample is measured. The biological sample measuring device comprises a mounting portion, a voltage application section, and a detection component. The biological sample measuring sensor is mounted to the mounting portion. The voltage application section applies a measurement voltage to a plurality of electrodes disposed along the capillary. The detection component eliminates the effect of seepage of the biological sample by pass-around at the end of the capillary, or the effect whereby the plasma component seeps into the reagent, and detects the degree to which the biological sample is introduced into the capillary, based on the output result for the voltage applied by the voltage application section to the electrodes. | 02-18-2016 |
| 20160054254 | Electron Mediator and Electrochemical Biosensor Employing the Same - Provided is an electron mediator system, which may include a first transition metal complex and a second transition metal complex, wherein a working potential of the electron mediator system may be substantially the same as a molar average of a working potential of the first transition metal complex and a working potential of the second transition metal complex. | 02-25-2016 |
| 20160077041 | ELECTROCHEMICAL DETECTION SYSTEM AND APPARATUS - The invention provides a method of probing for a nucleic acid comprising: contacting a nucleic acid solution with an oligonucleotide probe labelled with an electrochemically active marker, providing conditions at which the probe is able to at least partially hybridise with any complementary target sequence which may be present in the nucleic acid solution, selectively degrading either hybridised, partially hybridised or unhybridised nucleic acid probe, and electrochemically determining information relating to the electrochemically active marker. The invention further provides novel molecules with use in methods of the invention. | 03-17-2016 |
| 20160077050 | Underfill Management System For A Biosensor - A biosensor system including the underfill management system determines the analyte concentration in a sample from the at least one analytic output signal value. The underfill management system includes an underfill recognition system and an underfill compensation system. The underfill recognition system determines whether the test sensor initially is substantially full-filled or underfilled, indicates when the sample volume is underfilled so that additional sample may be added to the test sensor, and starts or stops the sample analysis in response to the sample volume. The underfill recognition system also may determine the initial degree of underfill. After the underfill recognition system determines the initial fill state of the test sensor, the underfill compensation system compensates the analysis based on the initial fill state of the test sensor to improve the measurement performance of the biosensor system for initially underfilled test sensors. | 03-17-2016 |
| 20160084794 | Underfill Recognition Biosensor - A biosensor with an underfill recognition system assesses whether to analyze a sample for one or more analytes in response to the volume of the sample. The underfill recognition system applies polling and test excitation signals to the sample. The polling signals generate one or more polling output signals, which maybe used to detect when a sample is present and to determine whether the sample has sufficient volume for analysis. The test excitation signal generates one or more test output signals, which may be used to determine one or more analyte concentrations in the sample. | 03-24-2016 |
| 20160139152 | Biosensor Using Cell That Expresses Chemosensory Receptor That Can Detect Sugar, And Alzheimer's Disease Diagnostic Apparatus Comprising Same - The present invention relates to a biosensor that uses a cell that expresses a chemosensory receptor that can detect sugar, and an Alzheimer's disease diagnostic apparatus comprising the same. The biosensor and the Alzheimer's disease diagnostic apparatus of the present invention can sensitively detect a particular sugar in a sample, more inexpensively and more quickly, by fixing a drosophila cell having an over-expressed target sensory receptor protein on the cell surface through genetic engineering, and can thereby be efficaciously used for diagnosing Alzheimer's disease. | 05-19-2016 |
| 20160153933 | ELECTROCHEMICAL SENSOR FOR DETERMINING AN ANALYTE CONCENTRATION | 06-02-2016 |
| 20160153961 | MEASUREMENT APPARATUS | 06-02-2016 |
| 20160161438 | SENSING PLATFORM FOR QUANTUM TRANSDUCTION OF CHEMICAL INFORMATION - A system for determining chemistry of a molecule in a high background interfering liquid environment by application of an electronic signal at a biased metal-electrolyte interface is disclosed. One or more of a resonant exchange of energy between one or more electrons exchanged by the metal and the electrolyte and vibrating bonds of a molecular analyte, for example, may be sensed by measuring small signal conductivity of an electrochemical interface. | 06-09-2016 |
| 20160169835 | BIOSENSOR | 06-16-2016 |
| 20220136993 | SINGLE MOLECULE NANOPARTICLE NANOWIRE FOR MOLECULAR ELECTRONIC SENSING - The disclosed embodiments relate to nanotechnology and to nano-electronics and molecular electronic sensors. In an exemplary embodiment, a nano-sensor having a nanoparticle complex attached at each end to a respective nano-electrode. An exemplary nanoparticle complex includes a biomolecule coupled at each end to a metallic nanoparticle to form a dumbbell-shaped molecular bridge. A method to manufacture single molecule dumbbell nanowires for forming conductive molecular bridges includes the steps of: providing a double-stranded nucleic acid with terminal 3′ thiol modification on both the strands conjugated to a gold (Au) nanoparticle (AuNP) on each end; purifying single biomolecule dumbbells from aggregates using size-exclusion chromatography; imaging the eluted products by electron microscopy to validate formation of single molecule dumbbells; trapping a single molecule dumbbell between a pair of nanoelectrodes on a substrate, the electrodes separated by a nanogap; and measuring the conductivity of a trapped single molecule dumbbell. | 05-05-2022 |
