BECTON, DICKINSON AND COMPANY Patent applications |
Patent application number | Title | Published |
20160138076 | Methods And Compositions For The Detection Of Beta-Lactamases - Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes. | 05-19-2016 |
20160121526 | Medical Access Device - An access device provides needleless access to patient fluid lines such as intravascular catheters. A septum assembly of the access device is formed from a frame integrally molded with a septum and provides access for a tubular portion, such as a male luer taper of a syringe, of a medical device. The frame of the septum assembly is bonded to the housing of the device, which minimizes axial and rotational movement between the septum and the housing, so that the access device properly operates through multiple uses. | 05-05-2016 |
20160090971 | Control Circuits For Electrochemical Pump With E-Valves - An electrochemical actuator drive system and method that provides for full control of an electrochemical pump system having at least three electrochemical actuators, including two valve actuators, and one pump actuator. The driving circuit is based on a standard H-bridge driving circuit wherein part of the circuit is shared among actuators. Because the system only needs to operate either the pump actuator or one of the valve actuators at any given time, part of the H-bridge driving circuit can be shared among the three actuators, thereby permitting the use of four half-bridge driving circuits. | 03-31-2016 |
20160082183 | Drug Delivery Devices, Systems, and Methods - This disclosure relates to drug delivery devices, systems, and methods. In some aspects, a drug delivery device includes an elongate member defining a fluid passage and an opening in fluid communication with the fluid passage, and a projection extending radially from the elongate member. A portion of the elongate member extending axially from the projection to a distal end of the elongate member has a length sufficient to allow the distal end of the elongate member to reach subdermal tissue of a patient when the elongate member is inserted into the patient and the projection is in contact with an outer surface of skin of the patient, and the opening is positioned at a location along the elongate member such that the opening is disposed within a dermis of the patient when the elongate member is inserted into the patient and the projection is in contact with the outer surface of the skin of the patient. | 03-24-2016 |
20160077011 | METHOD FOR TAGGING MATERIAL WITH SURFACE-ENHANCED SPECTROSCOPY (SES)-ACTIVE COMPOSITE NANOPARTICLES - Metal nanoparticles associated with a spectroscopy-active (e.g., Raman-active) analyte and surrounded by an encapsulant are useful as sensitive optical tags detectable by surface-enhanced spectroscopy (e.g., surface-enhanced Raman spectroscopy). | 03-17-2016 |
20160076072 | IMAGING CARTRIDGE, PIPETTE, AND METHOD OF USE FOR DIRECT SPUTUM SMEAR MICROSCOPY - An assembly for preparing a specimen is provided that may be configured to determine the presence of at least one microorganism specie in the specimen. The assembly may include a pipette configured to acquire a specimen from a sample and an imaging cartridge configured to be in fluid communication with the pipette. The imaging cartridge and the pipette may be configured to be irreversibly coupled such that the specimen is bio-contained within the imaging cartridge and the pipette when the imaging cartridge and pipette are coupled together. Associated methods of use are also provided. | 03-17-2016 |
20160074587 | SYSTEM AND METHOD FOR CAPTURING DOSE INFORMATION - A system for capture of dose delivery information is provided. The system includes a medication delivery device, a dose information capture device adapted to be attached to the medication delivery device, and a target element adapted to be attached to the medication delivery device. The target element comprises a magnet or ferrous element and the target element attaches to the medication delivery device on a dose delivery mechanism of the medication delivery device. The dose information capture device includes a magnetic position sensor adapted to detect a position of the target element. As an alternative to magnetic sensing, MEMS flow sensors, and the like may also be used. Exemplary systems preferably transmit dose information in real time to remote devices for further processing. | 03-17-2016 |
20160074572 | Needle Dispensing and Storing Apparatus for Medicament Delivery Device - A flip-open multi-pack assembly is provided which can contain a plurality of new pen needles, such as through the provision of a rectangular or tube-shaped shaped, hinged shell housing, wherein new pen needles can be stored in a plurality of user accessible openings each having a sterility barrier formed, for example, by covers that cover the non-patient end of the openings in which the new pen needles are contained. Used pen needles can be returned and stored in openings accessible by rotatably opening the shell housing. One or more of the openings within first and second opposite ends of the housing shell can be provided with a slidable internal holder within the device and are configured to releasably secure the inner shield of the new pen needle, and to then be pulled forward when the new pen needle is removed and lock at a forward position, and thereby create an interior space, accessible from an opposite end when the hinged housing is opened, for a used pen needle to be inserted and stored. | 03-17-2016 |
20160058941 | DRUG DELIVERY DEVICE - A drug delivery device for injecting medicament, the device including a main body having a surface for contacting a patient, an actuation button ( | 03-03-2016 |
20160051772 | Pen Needle Dispensing Apparatus - An apparatus is disclosed for storing and dispensing a pen needle for an injection device, including a packaging assembly including a pliable outer cover, the outer cover having a hub portion, a needle portion disposed at a distal end of the hub portion, and a flange disposed at a proximal end of the hub portion, the hub portion having internally protruding splines or other structures for engaging a hub of a pen needle. The hub portion is sufficiently pliable for a user to press gripping portions of the hub portion so that corresponding internal portions of the hub portion between the splines contacts the pen needle hub to increase a surface area contact between the outer cover and a pen needle therein. | 02-25-2016 |
20160051771 | Pen Needle Dispensing Apparatus - An apparatus is disclosed for storing and dispensing a pen needle for an injection device, including a packaging assembly including a pliable outer cover, the outer cover having a hub portion, a needle portion disposed at a distal end of the hub portion, and a flange disposed at a proximal end of the hub portion, the hub portion having internally protruding splines or other structures for engaging a hub of a pen needle. The hub portion is sufficiently pliable for a user to press gripping portions of the hub portion so that corresponding internal portions of the hub portion between the splines contacts the pen needle hub to increase a surface area contact between the outer cover and a pen needle therein. | 02-25-2016 |
20160051763 | Additive Force Device For Drug Delivery Pen For Intradermal Medication Injection - A method of amplifying an injection force of a drug delivery device, comprising the steps of storing energy in an additive force device, connecting the additive force device to the drug delivery device, setting a dose of medicament to be administered, and selectively releasing the stored energy of the additive force device to amplify an injection force of the drug delivery device. | 02-25-2016 |
20160051748 | Pen Needle Dispensing Apparatus - An apparatus is disclosed for storing and dispensing a pen needle for an injection device, including a packaging assembly including a pliable outer cover, the outer cover having a hub portion, a needle portion disposed at a distal end of the hub portion, and a flange disposed at a proximal end of the hub portion, the hub portion having internally protruding splines or other structures for engaging a hub of a pen needle. The hub portion is sufficiently pliable for a user to press gripping portions of the hub portion so that corresponding internal portions of the hub portion between the splines contacts the pen needle hub to increase a surface area contact between the outer cover and a pen needle therein. | 02-25-2016 |
20160030683 | SMART ADAPTER FOR INFUSION DEVICES - Smart sensors are employed to determine one or more of drug identification, dose, flow rate, concentration, agglomeration, and degradation and/or other characteristics of drug administration that can be detected via sensing technology. A smart sensor(s) can be coupled to or retrofitted onto injection pen injectors and/or drug delivery cartridges and/or infusion sets or cannulae, enabling infusion sets, pen injector systems or drug delivery cartridges to improve tracking of drug self-administration and stop medication errors that occur primarily through self or automated injection (e.g., due to incorrect or incomplete dosing, excessive dose or rate, incorrect drug, or drug degradation). | 02-04-2016 |
20160029977 | CONTINUOUS GLUCOSE MONITORING ON-BODY SENSOR HAVING A VISUAL DISPLAY - An on-body sensor (OBS) ( | 02-04-2016 |
20160028821 | DIRECT CGM CONNECTIVITY TO A CLOUD STORAGE NETWORK - A system and method is provided for a continuous glucose monitoring (CGM) system and the processing of data collected thereby. An internet gateway chip ( | 01-28-2016 |
20160024549 | BACTERIAL DETECTION CARTRIDGE - Described herein are methods and apparatus for rapid detection of microorganisms in biological samples (e.g. blood) for analysis to determine the presence or absence of infectious microorganisms in the samples. The apparatus includes a cartridge with a lid and a tray, a mechanism for isolating a bulk sample into multiple smaller samples, and a sensor disposed on the tray to determine the presence or absence of microorganisms. The cartridge lid includes projections that, in a first position, allow for sample to distribute evenly in the cartridge tray and, in a second position, isolate the sample into multiple smaller volume samples. The apparatus and method shorten the time-to-detection of a microorganism in a sample and reduce the steps required from sample collection to microorganism detection. | 01-28-2016 |
20160022179 | CONTINUOUS GLUCOSE MONITORING ON-BODY SENSOR - An on-body sensor (OBS) ( | 01-28-2016 |
20160015906 | Method and Apparatus for Delivering a Therapeutic Substance Through an Injection Port - Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed. | 01-21-2016 |
20160015867 | RECYCLED RESIN COMPOSITIONS AND DISPOSABLE MEDICAL DEVICES MADE THEREFROM - Syringe plunger rods comprising an elongate body formed from a composition comprising one or more of virgin material, a sterilization-stable recycled resin and a biobased compositions are described. Plunger rods comprising a plurality of ribs, some of which may have a plurality of openings, are also described. The plunger rods requiring less material while maintaining sufficient structural integrity to function properly. | 01-21-2016 |
20150374440 | Shipping Container Integrating A Sharps Disposal Container With A New Product Storage Container - A shipping container integrates a sharps disposal container with a new product storage container for shipping. The storage container stores new product. A sharps disposal container receives used sharps. One of the storage container and the sharps disposal container is disposed within the other of the storage container and the sharps disposal container for shipping. A lid is adapted to be connected to the outermost container of the sharps disposal container and the storage container for shipping and to a top of the sharps disposal container for receiving used sharps. | 12-31-2015 |
20150359960 | User-Actuated Storage Assembly For Injection Device - A storage assembly is removably connectable to a drug delivery device. A first chamber is disposed in the housing. A plurality of penetrating members are stored in the first chamber. A second chamber is disposed in the housing for storing the plurality of penetrating members after being used in an injection. A transfer drum disposed in the housing transfers one of the penetrating members from the first chamber to an injection position and from the injection position to the second chamber following an injection. | 12-17-2015 |
20150351669 | Reduced Size Optical Coupler for Fluorescence Detection - Optical systems are disclosed for use in identifying an analyte, such as glucose in blood or interstitial fluid (ISF), using a biomaterial, such as glucose binding protein (GBP), that is brought into contact with the analyte. An optical system includes a first filter adapted to reflect light emitted from a light-emitting diode to illuminate a fluorescent body, and further adapted to transmit light emitted from the fluorescent body, and a second filter adapted to separate light transmitted by the first filter into signal band light and reference band light. | 12-10-2015 |
20150347714 | MULTIFUNCTIONAL GLUCOSE MONITORING SYSTEM AND METHOD OF USING THE SAME - A multifunctional glucose monitoring system and method of measuring glucose level, determining insulin dosage, and indicating insulin dosage on a syringe is disclosed. The multifunctional glucose monitoring system includes standard functionality with respect to acquiring a blood glucose reading. However, in addition, the multifunctional glucose monitoring system includes a dosage algorithm for calculating an insulin dosage based on the blood glucose reading and any other useful parameters, and includes a built-in marking device for marking the calculated dosage level on the barrel of an insulin syringe that is installed in the body of the multifunctional glucose monitoring system. A method includes the steps of measuring the glucose level, determining an insulin dosage, and indicating the insulin dosage on a syringe. | 12-03-2015 |
20150328412 | Pen Needle Assembly - A pen needle is provided with a plastic non-patient end. Since the non-patient end needle does not contact the patient, the needle can be formed with a larger diameter, permitting more secure attachment to a medication pen and greater medication flow from the cartridge through the cannula. In addition, a two-part hub construction comprising a needle bearing sub assembly and an adapter for attachment to the pen body may be used to lower materials volume and costs, and reduce sharps disposal. In embodiments, a hub according to the invention may be provided with a shield that provides an audible and/or tactile indication when full penetration depth of the needle is achieved. Windows on the shield may reveal a color band on the hub at the full-penetration depth position to provide the user with a visual indication that the pen needle has been used. | 11-19-2015 |
20150328370 | Device and Method for Inhibiting Movement of a Medical Device in a Patient - A medical device such as a cannula, catheter, needle or biosensing probe includes an elongated body for penetrating, inserting and/or positioning in or through the skin of a patient. The elongated body has an outer surface that when positioned in the patient with a coefficient of friction sufficient to inhibit movement between the elongated body on the skin at the insertion site to inhibit irritation at the infusion site. A lubricious coating is provided on the elongated body to assist in penetration and/or insertion of the elongated body into the patient. The lubricious coating can be removed by a shearing action by the insertion of the elongated body into the patient and/or by absorption of the lubricious coating to expose the outer surface of the elongated member. | 11-19-2015 |
20150323465 | SURFACE ENHANCED SPECTROSCOPY-ACTIVE COMPOSITE NANOPARTICLES - Submicron-sized particles or labels that can be covalently or non-covalently affixed to entities of interest for the purpose of quantification, location, identification, tracking, and diagnosis, are described. | 11-12-2015 |
20150320941 | PEN NEEDLE HUB HAVING INCREASED CONTACT AREA - A pen needle assembly having a hub with an increased surface area that contacts a patient's skin is provided. The increased contact area of the hub with the patient's skin during injection of a cannula decreases the pressure exerted against the patient's skin, thereby increasing the comfort of the patient. A bonding adhesive is disposed on an outer surface of the hub, thereby decreasing the required curing time of the adhesive. Additionally, the increased contact area, between the cannula adhesive and hub increases the strength of the bond therebetween. | 11-12-2015 |
20150306370 | ANTIMICROBIAL STOPCOCK MEDICAL CONNECTOR - Various embodiments of an antimicrobial stopcock medical connector is provided. More specifically, the present invention relates to a stopcock tap having fluid channels provided on portions of the outer surface of the stopcock tap, whereby fluid bypasses the stopcock through the fluid channels by flowing between the outer surface of the stopcock tap and the inner surface of the stopcock housing. Some embodiments further comprise an antimicrobial coating or insert that is provided in the one or more fluid channel, whereby fluid flowing through the fluid channels contacts the antimicrobial coating or an antimicrobial agent that is eluted from the antimicrobial coating. Further still, some embodiments of the present invention comprise an antimicrobial groove that is positioned opposite the fluid channel, whereby when the stopcock is in an “off” position, the antimicrobial groove contacts fluid within a blocked port thereby preventing microbial growth therein. | 10-29-2015 |
20150306369 | ANTIMICROBIAL CAPS FOR MEDICAL CONNECTORS - The present invention relates to a cap for a medical connector. More specifically, the present invention related to an antimicrobial cap for placement over a connector, wherein various features of the antimicrobial cap maintain the connector in an antiseptic state. | 10-29-2015 |
20150306368 | PORTED CATHETER OR FEMALE LUER FITTING WITH ANTIMICROBIAL SEPTUM - Ports, such as the ports of ported catheters or of female luer fittings, can be configured to include an antimicrobial septum for disinfecting devices that are attached to the ports. The antimicrobial septum can be positioned within the lumen of the port. The lumen can include an annular recess for securing the antimicrobial septum in place during use. The antimicrobial septum can include an antimicrobial lubricant which transfers onto a device, such as a male luer, as the device passes through the septum thereby killing any microbes that may be present on the surfaces of the device. The antimicrobial septum can be configured in various shapes including a continuous disk shape, a ring shape, or an elongated ring or tube shape. When configured as a ring or tube shape, the inner surfaces of the antimicrobial septum may contain slits or grooves. The slits or grooves can facilitate the compression of the septum as a device passes through it, while also increasing the surface area of the septum on which antimicrobial lubricant can be contained. | 10-29-2015 |
20150306364 | CATHETER TUBING WITH EXTRALUMINAL ANTIMICROBIAL COATING - Various methods can be employed to apply an antimicrobial coating to the outer surface of catheter tubing. The antimicrobial coating minimizes the risk of microbe colonization on the outer surface of the catheter tubing when the catheter tubing is positioned within the vasculature of a patient. A catheter can be manufactured using a pre-treatment process which applies the antimicrobial coating to the catheter tubing prior to applying a lubricant over top of the coating. The lubricant can function to retain the coating on the outer surface and also to limit the diffusion of the antimicrobial agent from the coating. A catheter can include an antimicrobial coating that does not block the visibility of flashback. Because the antimicrobial coating can be minimally transparent, the coating can be applied to the outer surface in a striped pattern or other pattern that leaves a portion of the outer surface uncoated or minimally coated. The flashback will then remain visible through the portions of the catheter tubing where no coating or minimal coating is present. | 10-29-2015 |
20150306351 | SYSTEMS AND METHODS FOR PROVIDING AN INTEGRATED PACKAGE AND GRIP FOR CATHETER - An integrated individual package and an introducer needle or wire for placing a catheter in a patient's vasculature, wherein the package doubles as a grip for placing the catheter. Prior to activation, the catheter is coaxially and slidably disposed over the introducer needle and the catheter and introducer needle assemblies are contained within the integrated package grip. The device is activated as the catheter and introducer needle assemblies are simultaneously transitioned from a closed position to an open position wherein the catheter and introducer needle assemblies are oriented for insertion into a patient's vasculature. Following placement of the catheter in a patient's vasculature, the device is deactivated as the introducer needle is withdrawn and transitioned from the open position to resume the closed position. The package grip comprises a sharps shuttle to protect a clinician from needle stick injuries. | 10-29-2015 |
20150306345 | ANTIMICROBIAL OBTURATOR FOR USE WITH VASCULAR ACCESS DEVICES - An obturator can include antimicrobial features which assist in sterilizing or maintaining the sterility of fluid contained within a vascular access device while the device is not being used for infusion or other access to the patient's vasculature. These antimicrobial features include antimicrobial coatings applied to various surfaces of an obturator and antimicrobial components bonded or otherwise secured to an obturator. Various combinations of antimicrobial coatings and/or components can be used on an obturator as necessary to provide a desired amount of antimicrobial agents within a particular enclosed volume of a vascular access device. | 10-29-2015 |
20150306318 | APPARATUS AND METHOD FOR IMPROVED MEDICATION DOSING - An apparatus and method for improving medication dosing is provided. The apparatus preferably includes a template configured to fit over a barrel of a syringe, the template having a substantially opaque exterior and at least one substantially transparent section in the substantially opaque exterior permitting a view of the syringe barrel and a distal end of a plunger within the barrel of the syringe. A method includes the steps of positioning a dosing template on a syringe, operating a plunger within the syringe, and drawing a predetermined dose of medication into the syringe. | 10-29-2015 |
20150299315 | NON-B-LINEAGE CELLS CAPABLE OF PRODUCING ANTIBODY - Disclosed herein are methods of identifying and methods of isolating antibody-producing cells and cells capable of producing antibodies, including V cells, a non-B-cell-lineage class of cells capable of producing antibody. Disclosed herein are kits for detection and isolation of antibody-producing cells and cells capable of producing antibodies. Disclosed herein are methods of making antibodies. | 10-22-2015 |
20150297825 | SPLIT PISTON METERING PUMP - A micropump according to the invention uses axially oriented pistons to define a pump volume. Translating the pistons axially with respect to each other within a pump housing draws a metered amount of fluid into the pump volume from a reservoir port for delivery to a cannula port when the space is collapsed. Radially situated seals on the pistons cooperate with the axial movement to close off and open the cannula port and the reservoir port respectively at different positions of the piston stroke. | 10-22-2015 |
20150258272 | Reconstituting Infusion Device - A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed. | 09-17-2015 |
20150247819 | METHODS AND APPARATUS FOR RAPID DETECTION OF INFECTIOUS MICROORGRANISMS - An array of micro-chambers | 09-03-2015 |
20150231384 | IV ACCESS PORT CAP FOR PROVIDING ANTIMICROBIAL PROTECTION - A cap is configured to provide antimicrobial protection to a female luer port of an intravenous device. The cap distributes an antimicrobial solution within the intraluminal surfaces of the port when the cap is connected to the port. A cap may also be designed to distribute an antimicrobial solution around the exterior surfaces of the port. Once connected to a port, the cap can form a seal that minimizes the evaporation of the antimicrobial solution from within the lumen of a port. The cap can therefore provide antimicrobial protection against another device that is connected to the port once the cap is removed. | 08-20-2015 |
20150231380 | SYSTEMS AND METHODS FOR PROVIDING AN ANTIMICROBIAL DISPENSING APPLICATOR - A handheld antiseptic dispensing applicator device having a reservoir for storing an antiseptic agent, the reservoir being coupled to an applicator pad, and a defeatable membrane or barrier being interposed between the reservoir and the applicator pad. Embodiments of the device comprise a squeezable reservoir, wherein the internal hydraulic pressure of the squeezable reservoir is increased via user applied forces to thereby defeat the membrane releasing the antiseptic agent contained therein which is then absorbed by the applicator pad. The defeatable barrier or membrane is also removable or may be defeated in connection with other mechanisms according to various embodiments. | 08-20-2015 |
20150231338 | INTRADERMAL DELIVERY DEVICE INCLUDING A NEEDLE ASSEMBLY - A drug delivery device including a needle assembly facilitates making intradermal injections using a variety of drug container types such as a syringe. A hub supports the needle while a limiter surrounds the needle. The limiter includes a skin engaging surface that is adapted to be received against the skin of an animal to be intradermally injected. A forward end of the needle extends beyond the skin engaging surface a selected distance to limit a depth that the needle penetrates into the animal's skin. | 08-20-2015 |
20150231307 | ANTIMICROBIAL INSERTS FOR MEDICAL DEVICES - Inserts can be formed with elution characteristics to cause the inserts to elute an antimicrobial agent when subject to a fluid within a medical device. An insert can be formed with a desired geometry to allow the insert to be compression fit within a medical device to prevent the insert from moving or becoming dislodged once inserted into the medical device. The material may also be hygroscopic so that the insert swells when subject to a fluid thereby enhancing the compression fit of the device within the medical device. In some cases, the material can be reinforced using an internal structure. Inserts can be formed in many ways including by casting, thermoforming, or extrusion. In some cases, the inserts can be formed using a peel-away sleeve or material. The peel-away sleeves can be formed of a non-sticky material which facilitates removal of the inserts once the inserts have cured. | 08-20-2015 |
20150185225 | SYSTEM AND METHOD FOR DYNAMICALLY CALIBRATING AND MEASURING ANALYTE CONCENTRATION IN DIABETES MANAGEMENT MONITORS - An optical analyte sensor and diabetes management system is provided. The sensor preferably includes a hydrogel matrix for receiving a sample containing an analyte at unknown concentration, a light emitter for emitting light at a stimulation frequency, a light receiver for receiving a fluorescence signal at a first isosbestic frequency, and at a second frequency, for measuring an intensity of the fluorescence signal and the first and second frequencies. A processor determines a concentration of the analyte based on the respective intensities. | 07-02-2015 |
20150157786 | Self-Injection Device - A drug delivery device ( | 06-11-2015 |
20150152473 | IMMUNO-AMPLIFICATION - A high-sensitivity, low-background immuno-amplification assay is provided, which offers a streamlined workflow suitable for high-throughput assays of clinically relevant samples, such as blood and other bodily fluids. The assay comprises the use of two proximity members that each comprise an analyte-specific binding component conjugated to an oligonucleotide. Binding an analyte brings the oligonucleotide moieties of the proximity members in sufficiently close contact that the oligonucleotides form an amplicon. The presence of the analyte then is detected through amplification of the amplicon and detection of the amplified nucleic acids. The sensitivity of the assay of the present invention is improved by preventing spurious or non-specific amplicon formation by proximity members that are not complexed with an analyte. | 06-04-2015 |
20150141932 | Dose Dividing Delivery Device - A simple method and device enabling a unit dose from a reservoir is provided. The dose is drawn into the reservoir and is then expelled from the device by depressing a plunger. The plunger has features which divide the dose into discrete intervals. As the plunger is moved during delivery, the features on the plunger and the features connected to a barrel interact to provide for intermittent stops to the delivery. Other aspects of the device provide for reduced dead space, safety and selective interconnection with other devices. Thus, the device divides the dose. | 05-21-2015 |
20150125895 | FORMULATIONS AND PROCESS FOR ISOLATING VIABLE MICROORGANISM FROM POSITIVE BLOOD CULTURES - Various embodiments disclosed herein provide for reagents and methods for rapidly isolating viable microbial cells, including | 05-07-2015 |
20150119863 | RETENTION FEATURE FOR SOFT INTERFACE CONNECTION - A retention feature configured to provide interference between a threaded connection of a Luer access device and a separate device, wherein the Luer access device further comprises a septum that provides a soft interfaced between the two threadedly connected devices. The retention features of the instant invention are designed to provide the user with a tactile sensation of a tightening threaded connection, despite a soft interface between the interconnected devices. The retention features of the instant invention further prevent “spring back” and unintentional disengagement of the interconnected devices. | 04-30-2015 |
20150118677 | SAMPLE PREPARATION FOR FLOW CYTOMETRY - Described herein are methods and reagents for identifying and analyzing at least one microorganism (e.g. bacteria) in a sample and reducing the background signal intensity obtained when analyzing the sample by flow cytometry. The sample is prepared by combining the sample with a background signal-reducing molecule or with a nucleic acid stain covalently linked to a quencher. A portion of the particulate matter in the sample can optionally be removed with a resin prior to staining with a nucleic acid stain. | 04-30-2015 |
20150112276 | Medical Injector with Ratcheting Plunger - A medical injector is provided herein having a body with a displaceable plunger. The plunger includes a plurality of spaced-apart ratchet teeth disposed along the length thereof. At least one indexer is provided formed to engage the plunger, wherein the indexer is configured to allow the plunger to displace distally towards a distal end of the body but not proximally towards a proximal end of the body. The medical injector also includes an actuator having an engagement portion formed to engage one or more of the ratchet teeth. The actuator is displaceable to a ready state, the engagement portion being displaced proximally relative to the plunger with the actuator being displaced to the ready state. The indexer prevents proximal movement of the plunger thereby allowing the engagement portion to by-pass one or more of the ratchet teeth with the actuator being displaced to the ready state. In addition, the actuator is displaceable from the ready state to cause actuation of the medical injector. The displacement from the ready state causes distal displacement of the engagement portion with the engagement portion engaging one or more of the ratchet teeth and causing distal displacement of the plunger with the engagement portion. Advantageously, the subject invention provides a plunger for a medical injector which may be controllably advanced with a minimum number of cooperating parts. | 04-23-2015 |
20150112275 | Medical Injector with Ratcheting Plunger - A medical injector is provided herein having a body with a displaceable plunger. The plunger includes a plurality of spaced-apart ratchet teeth disposed along the length thereof. At least one indexer is provided formed to engage the plunger, wherein the indexer is configured to allow the plunger to displace distally towards a distal end of the body but not proximally towards a proximal end of the body. The medical injector also includes an actuator having an engagement portion formed to engage one or more of the ratchet teeth. The actuator is displaceable to a ready state, the engagement portion being displaced proximally relative to the plunger with the actuator being displaced to the ready state. The indexer prevents proximal movement of the plunger thereby allowing the engagement portion to by-pass one or more of the ratchet teeth with the actuator being displaced to the ready state. In addition, the actuator is displaceable from the ready state to cause actuation of the medical injector. The displacement from the ready state causes distal displacement of the engagement portion with the engagement portion engaging one or more of the ratchet teeth and causing distal displacement of the plunger with the engagement portion. Advantageously, the subject invention provides a plunger for a medical injector which may be controllably advanced with a minimum number of cooperating parts. | 04-23-2015 |
20150112274 | MULTIPLE USE DISPOSABLE INJECTION PEN - A medication injection pen ( | 04-23-2015 |
20150105739 | SELF-INJECTION DEVICE HAVING NEEDLE COVER WITH ACTIVATION PREVENTER - A drug delivery device, including a body ( | 04-16-2015 |
20150094666 | DUAL SHIELDED SYRINGE - A dual shield mechanism is provided for passive protection of a syringe cannula. The automatic shield system may be used with a re-fillable syringe, and may be adapted for filling the syringe from a vial using a novel vial adapter without triggering the passive shielding mechanism. | 04-02-2015 |
20150094652 | NEEDLE MOUNTING FEATURE FOR ENSURING PROPER RECONSTITUTION SEQUENCE - In one aspect, a medical injector is provided herein having a body and an overcap releasably attached to the body configured to prevent mounting of a needle prior to mixing of components within the body. In a further aspect, a slidable collet may be provided useable to urge resilient members from an outward disrupted state inwardly to collectively define a needle mount. Advantageously, a medical injector is provided which ensures proper sequence in preparation of the device, particularly with respect to the step of allowing mounting of a medical needle to the device subsequent to preparation of the medicament to be administered. | 04-02-2015 |
20150088067 | ADJUSTABLE PENETRATION DEPTH SYRINGE - A syringe is provided with an assembly received on the distal end for adjusting the penetration depth. In embodiments, the assembly includes a collar attached to the syringe hub which moves with respect to the needle between axial positions depending on the desired needle penetration depth. The adjustable penetration depth syringe is useful in the context of self-administered drugs such as insulin, where a longer length needle is needed to fill a syringe from a vial, but a shorter penetration depth is preferred for administering a subcutaneous injection. | 03-26-2015 |
20150087005 | Phosphorothioate Oligonucleotide-Labeling of White Blood Cells - The present invention provides labeling and capture reagents that comprise phosphorothioate oligonucleotides ODN). The PS-ODN bind to all white blood cells (leukocytes) in an indiscriminative fashion and enable the labeling, capture, or concentration of leukocytes in a manner that preserves the antigenic integrity of the cells. Methods for the use of phosphorothioate oligonucleotides are provided. | 03-26-2015 |
20150080807 | SELF-INJECTION DEVICE WITH INDICATOR FOR INDICATING PROPER CONNECTION OF COMPONENTS - A self-injection device includes a visual indicator for visually indicating that a main body and a cartridge holder are properly connected to each other. In one embodiment, the visual indicator includes a visual marking on the cartridge holder and a visual marking on the main body, such that when the cartridge holder and the main body are properly connected, the visual markings are aligned with each other. A self-injection device that includes an indicator for a dose window is also disclosed. | 03-19-2015 |
20150080800 | Microinfuser with Automatic Needle Retraction | 03-19-2015 |
20150080799 | INFUSION DEVICE WITH SAFETY FEATURE FOR PREVENTING INADVERTENT ACTIVATION - A safety feature for a wearable infusion device is disclosed. The safety feature is configured to prevent accidental activation of the infusion device by protecting the activation button of the infusion device prior to and after the actuation of the activation button. The safety feature includes a wall section that protrudes from the main body of the infusion device in the vicinity of the activation button. A cover device covers the activation button prior to the actuation of the activation button. The cover device slides on the main body of the infusion device. When the cover covers the activation button, movement of the cover is restricted by the protruding wall section adjacent to the activation button, to hold the cover in position over the activation button. | 03-19-2015 |
20150073384 | Injection Mechanism Utilizing a Vial - An injection device is provided for delivering a liquid medicament. The injection device includes a housing with a first chamber for storing a supply of the medicament. The first and second chambers are coupled within the housing. The second chamber is in fluid communication with the first chamber. The injection device also includes an outlet port for dispensing the medicament outside the housing. The outlet port is coupled to the housing and in fluid communication with one of said first and second chambers. | 03-12-2015 |
20150065991 | VIAL DOSING SYSTEMS AND METHODS - Vial dosing systems and methods are disclosed. A vial dosing device includes a connecting body coupleable to a vial, a cannulated plunger having a proximal end coupled to the connecting body, a dose chamber adapted to slidably receive a distal end of the cannulated plunger and to expel medicament through a distal end of the dose chamber, and a plunger tip check valve coupled to the cannulated plunger and adapted for fluid flow from the cannulated plunger through the plunger tip check valve into the dose chamber. | 03-05-2015 |
20150057612 | DUAL CHAMBER AND GEAR PUMP ASSEMBLY FOR A HIGH PRESSURE DELIVERY SYSTEM - A high pressure delivery device for delivering a medicament includes a first chamber for storing a supply of the medicament and a second chamber in fluid communication with the first chamber. A fluid connection path is in fluid communication with the second chamber for administering the medicament. A valving system is in fluid communication with the first chamber, the second chamber and the fluid connection path. The valving system allows a dose of the medicament to be injected from the first chamber into the second chamber while substantially preventing backflow of the dose into the first chamber and substantially preventing leakage through the fluid connection path. The valving system also allows the dose in the second chamber to be administered through the fluid connection path while substantially preventing the dose from flowing back into the first chamber. | 02-26-2015 |
20150057161 | HIGH-RESOLUTION TRANSCRIPTOME OF HUMAN MACROPHAGES - The invention is based on the finding of specific surface markers for M1-like (classically activated) and M2-like (alternatively activated) macrophages and provides for a method for the identification, characterization and isolation of M1-like and M2-like macrophages based on the abundance of said surface markers and for means for performing such method. | 02-26-2015 |
20150056634 | Methods for Preparing Dry Formulations of Glucose Binding Protein - Methods and compositions for preparing dry formulations of Glucose Binding Proteins (GBPs) are disclosed. The GBPs may be stored as a dry formulation without significant loss of activity. After reconstitution, the GBPs may be used to determine the glucose concentration of a sample. | 02-26-2015 |
20150050667 | Cell-Surface Signatures for Isolating Neurons from Cell Cultures Derived from Pluripotent Stem Cells - The inventors disclose methods and systems that provide for the isolation and purification of neurons directly from heterogeneous cell cultures. The expression of various cell adhesion molecules was examined in pluripotent stem cells. Changes in the expression of one or more of these molecules correlates with the progression of cells from non-lineage committed to neural cells. Using one or more antibodies for these molecules in combination with antibodies specific for CD200 will enable one to identify and isolate neurons from a population cells. | 02-19-2015 |
20150050651 | NUCLEIC ACIDS FOR NUCLEIC ACID AMPLIFICATION - Nucleic acids sequences that can be used for nucleic acid amplification, for example quantitative nucleic acid amplification, are provided herein. | 02-19-2015 |
20150042364 | DETECTION METHOD AND APPARATUS FOR DETECTING MICROBIAL GROWTH - A system and method is provided for non-invasively measuring changes in a specimen suspected of containing one or more microbes, by monitoring changes in the dielectric constant of the specimen caused by metabolic processes of such microbes. | 02-12-2015 |
20150038910 | BLOOD CONTROL CATHETER VALVE EMPLOYING ACTUATOR WITH FLEXIBLE RETENTION ARMS - The present invention extends to a blood control catheter valve for use in a catheter adapter. The blood control catheter value employs an actuator for bypassing a septum to open the blood control catheter valve. The actuator includes flexible retention arms positioned on one end which retract into the body of the actuator while the end of the actuator passes through the septum, and then expand outwardly to maintain the actuator positioned within the septum. This design facilitates the manufacturing of catheter adapters (as well as blood control catheter valves and other components that attach to the catheter adapter) because the design can reduce the tolerance requirements of such components. Further, the design provides a reliable blood control catheter valve that does not require the catheter adapter to be increased in size to accommodate the valve. | 02-05-2015 |
20150038909 | INTERLOCKING NEEDLE HUB AND CATHETER HUB ACTUATOR TO INCREASE RIGIDITY OF IV CATHETER ASSEMBLY - The present invention extends to a design of a needle hub and an actuator of a catheter assembly that allows the needle hub and actuator to interlock within the catheter hub. This interlocking allows the needle hub to be inserted into the catheter hub thereby increasing the rigidity of the catheter assembly. The interlocking can be accomplished by forming channels in the proximal end of the actuator and corresponding protrusions from the distal end of the needle hub. In some embodiments, the channels and protrusions can be formed at the top and bottom of the catheter hub and needle hub respectively to thereby increase the vertical rigidity of the catheter assembly. The increase in vertical rigidity can prevent flexing of the catheter hub with respect to the needle shield when a downward force is applied to the catheter assembly such as is common during insertion of the needle. | 02-05-2015 |
20150025503 | Wireless Communication for On-Body Medical Devices - Apparatuses, systems and methods for the wireless communication of medical devices in a subcutaneous fluid delivery system are disclosed. A system for subcutaneous fluid delivery includes a primary patch pump adapted to attach a first infusion cannula to a user and to perform a plurality of primary patch pump functions, and a secondary patch pump adapted to attach a second infusion cannula to a user. The secondary patch pump is further adapted to perform a plurality of secondary patch pump functions substantially similar to the plurality of primary patch pump functions if an error condition associated with the primary patch pump is determined. | 01-22-2015 |
20150025473 | MEDICAL CANNULA PACKAGE - A package for a medical cannula with a hub, such as a pen needle, is disclosed. The package includes a cover for receiving a medical cannula and for engaging a hub of the medical cannula. The cover has open ends that are in communication through the cover. The packaging also includes a sterility barrier for the cover. | 01-22-2015 |
20150025170 | Hydrogel Adhesion to Molded Polymers - Methods for adhering a hydrogel matrix to a molded polymer substrate and its use as a biosensor, e.g., a continuous or episodic glucose monitor, are disclosed. The presently disclosed subject matter provides a method for adhering a hydrogel matrix to a molded polymer substrate, the method comprising: (a) molding a polymer comprising one or more polymer chains with an oxidizer to form a molded polymer substrate; (b) providing a hydrogel matrix comprising a hydrogel, a component comprising one or more acrylate groups or another functional group that can form one or more radicals upon polymerization in the molded polymer substrate, and a photo initiator; (c) combining the molded polymer substrate and the hydrogel matrix; and (d) curing the combined molded polymer substrate and hydrogel matrix for a period of time. | 01-22-2015 |
20150018641 | Fiber Optic Device for Sensing Analytes and Method of Making Same - A device for sensing analyte concentration, and in particular glucose concentration, in vivo or in vitro is disclosed. A sensing element is attached to the distal end of an optical conduit, and comprises at least one binding protein adapted to bind with at least one target analyte. The sensing element further comprises at least one reporter group that undergoes a luminescence change with changing analyte concentrations. Optionally, the optical conduit and sensing element may be housed within a cannulated bevel. | 01-15-2015 |
20150011937 | CONSTANT RATE FLUID DELIVERY DEVICE WITH SELECTABLE FLOW RATE AND TITRATABLE BOLUS BUTTON - A wearable, self-contained drug infusion device is disclosed that is capable of achieving the precise flow rate control needed for dose-critical drugs such as insulin. In preferred embodiments of the device, at least two flow channels are utilized in conjunction with a series of valves for providing a user with selectable, constant flow rate control. The device can be made with small dimensions so that it can be worn by the user with a minimum of discomfort and inconvenience. In addition, the simple mechanical nature of the device provides the user with close control over the flow rate, which is required for safe and effective delivery of insulin and other drugs. Also, the absence of electronic components allows the device to be manufactured inexpensively. The device is provided with a first channel that is long and narrow, functioning as a flow restrictor. The first channel is preferably provided in a serpentine pattern. A second channel is also provided that has a larger cross section so that flow is not restricted. A series of valves are used to force the flow of fluid through a selectable portion of the serpentine portion of the first channel before entering the remainder of the second channel and flowing to the delivery cannula. In one embodiment of the device, a needle port is provided in fluid communication with the delivery cannula for delivering bolus injections. In another embodiment, a bolus button is provided for delivering bolus injections. A flow restrictor is preferably included in the bolus button to limit the rate at which the bolus button refills. | 01-08-2015 |
20150010939 | Flow Cytometric Systems for Sterile Separation of Magnetically Labeled Sample Components - Systems for sterile separation of magnetically labeled sample components and methods for using the same are provided. Embodiments of the systems include a magnetic separation device and a pliant sample container, where a portion of the pliant sample container is operatively coupled under pressure to the magnetic separation device. Also provided are methods of using the systems, as well as pliant sample containers configured for use with the subject systems and methods. | 01-08-2015 |
20140379273 | System For Improved Interpretation of Physiological Data and Presentation of Physiological Condition Management Information - Systems, devices and methods for managing a physiological condition are configured to store predetermined output segments of content, analyze physiological data and other user information, and generate user-friendly information that provides an interpretation of the data (e.g., identifies selected data points, or determines pattern of physiological data over selected period(s)). An output segment management system with rules engine and method combines selected output segments to generate a presentation or message (e.g., with text, graphical, multimedia, video and/or audio information). The resulting presentation or message provides user information such as an explanation of selected data with selected user information incorporated therein, and optional recommendations (e.g., suggested user actions based on a designated protocol such as a clinical protocol). | 12-25-2014 |
20140378910 | Angled Retracting Sheath for Safety Needle - A safety needle device having a housing, a retractable sheath, and a needle cannula. The retractable sheath includes a tubular portion that is slideably mounted about a portion of the housing to completely or partially encase the length of the cannula. The retractable sheath includes a sheath bevel at the distal end having a blunted or angled tip. The angled tip being configured to suitable injection angles and may be fixed or rotatable. The sheath bevel may include a skin-engaging contact surface at the distal end. The needle may be connected to a needle hub at the proximal end of the housing and includes a needle bevel at the distal end. The sheath bevel and needle bevel may be offset from each other. A safety needle device having a retractable sheath having a graduated injection depth gauge to indicate needle penetration is also disclosed. | 12-25-2014 |
20140350487 | OUTER COVER OF A PEN NEEDLE FOR A DRUG DELIVERY PEN - A connecting member removably connects a plurality of pen needles together, thereby providing a convenient way for a patient to carry multiple pen needles. The connecting member may be integrally formed with the outer cover of the pen needle or may be a separate member that removably receives the pen needle. An outer cover of a pen needle is provided with gripping means to facilitate gripping and handling of the outer cover. A lid connects to the outer cover to seal the outer cover. The lid also has gripping means to facilitate gripping and handling the lid. A cap is provided that has a first opening for receiving a first end of the outer cover and a second opening for receiving a second end of the outer cover. | 11-27-2014 |
20140350485 | INFUSION DEVICE WITH RELEASABLE FLUID CONNECTOR - An infusion set system, including a base and a fluid connector removably coupleable thereto is disclosed. The fluid connector includes a fluid path portion and at least one connector latch displaceably connected to the fluid path portion and displaceable to a latching position in which at least a portion of the connector latch extends into the fluid path portion, which includes a cannula extending from a top interior surface thereof, and a plurality of internal sidewalls corresponding to at least two of a plurality of flat side surfaces of at least one of a base section and a base latch, thereby facilitating connection between the base and the fluid connector in a plurality of discrete rotational connecting positions. When the fluid connector is locked to the base, the at least one connector latch engages a base latching portion of the base and restricts proximal displacement of the fluid connector. | 11-27-2014 |
20140343897 | SYSTEMS AND METHODS FOR EFFICIENT CONTOURS AND GATING IN FLOW CYTOMETRY - Methods and systems for efficient contour and gating in flow cytometry are provided. Event data is compressed to reduce the number of points needed to represent polygon contours for the event data. Selection of a level within the contour then causes the generation of a gate. This allows limited resource devices, such as touchscreen wireless devices, to render and gate flow cytometry data in a resource efficient manner. | 11-20-2014 |
20140338187 | Medical Needle Removal and Storage Device - An apparatus for removing a needle from a needle holder, including a grasping unit for selectively grasping the needle; a receiving unit for receiving the needle holder, displaceably disposed relative to the grasping unit; a biasing member biasing the receiving unit in a first direction; and separating means for separating the entire needle from the needle holder. Preferably, the needle is heated to melt, soften, or otherwise weaken a material and/or adhesive connecting the needle with the needle holder. Preferably the heating is electrical heating, including completing an electrical circuit through the needle and passing current through the needle, and/or passing current through a heating element. | 11-20-2014 |
20140338186 | Medical Needle Removal and Storage Device - An apparatus for removing a needle from a needle holder, including a grasping unit for selectively grasping the needle; a receiving unit for receiving the needle holder, displaceably disposed relative to the grasping unit; a biasing member biasing the receiving unit in a first direction; and separating means for separating the entire needle from the needle holder. Preferably, the needle is heated to melt, soften, or otherwise weaken a material and/or adhesive connecting the needle with the needle holder. Preferably the heating is electrical heating, including completing an electrical circuit through the needle and passing current through the needle, and/or passing current through a heating element. | 11-20-2014 |
20140338171 | Medical Needle Removal and Storage Device - An apparatus for removing a needle from a needle holder, including a grasping unit for selectively grasping the needle; a receiving unit for receiving the needle holder, displaceably disposed relative to the grasping unit; a biasing member biasing the receiving unit in a first direction; and separating means for separating the entire needle from the needle holder. Preferably, the needle is heated to melt, soften, or otherwise weaken a material and/or adhesive connecting the needle with the needle holder. Preferably the heating is electrical heating, including completing an electrical circuit through the needle and passing current through the needle, and/or passing current through a heating element. | 11-20-2014 |
20140324023 | DRUG DELIVERY SYSTEM WITH A DELAY MECHANISM - Accordingly, it is an aspect of the present invention to provide a medicament delivery system with a delay mechanism to ensure dose completion prior to activation of at least one subsystem or operation. The foregoing and/or other aspects of the present invention are achieved by providing a medicament delivery system, including a medicament container and a delay mechanism that is activated prior to completion of medicament delivery from the medicament container. The delay mechanism automatically activates a subsystem or initiates an operation subsequent to completion of medicament delivery. The foregoing and/or other aspects of the present invention are also achieved by providing a method of delivering a medicament, the method including receiving an activation command, and in response to receiving the activation command, releasing an ejection mechanism to eject medicament from a container. | 10-30-2014 |
20140323980 | MEDICAL INJECTOR WITH RATCHETING PLUNGER - A medical injector has a body with a displaceable plunger. The plunger includes a plurality of spaced-apart ratchet teeth disposed along the length thereof. At least one indexer is provided to engage the plunger, wherein the indexer is configured to allow the plunger to displace distally toward a distal end of the body but not proximally toward a proximal end of the body. The medical injector also includes an actuator having an engagement portion formed to engage one or more of the ratchet teeth. The actuator is displaceable to a ready state, the engagement portion being displaced proximally relative to the plunger with the actuator being displaced to the ready state. The indexer prevents proximal movement of the plunger, thereby allowing the engagement portion to bypass one or more of the ratchet teeth with the actuator being displaced to the ready state. In addition, the actuator is displaceable from the ready state to cause actuation of the medical injector. The displacement from the ready state causes distal displacement of the engagement portion with the engagement portion engaging one or more of the ratchet teeth and causing distal displacement of the plunger with the engagement portion. | 10-30-2014 |
20140323963 | MIXING PEN NEEDLE - An injection device is provided with dual medicament chambers and a mixing pen needle assembly, whereby predetermined dosages of two medicaments can be provided to a mixing reservoir in the pen needle assembly and delivered simultaneously with the injection device. | 10-30-2014 |
20140322746 | Multi-Way Sorter System and Method - Provided herein are improved multi-way cell sorter systems and methods. For example, provided are systems and methods for the collection of cells that are sorted in multiple directions. The systems and methods allow for the construction of a multi-way sorter (e.g., a ten-way sorter in the space that currently only allows four-way sorting). In addition the device may actively sense the arrival of drops (with cells of interest) at a sample tube, and trigger an alarm when the drops' arrivals deviate from an expected pattern. | 10-30-2014 |
20140316379 | NEEDLE SHIELDING ASSEMBLIES AND INFUSION DEVICES FOR USE THEREWITH - A needle assembly includes a needle and a needle shield device. The needle shield device includes an inner shield connectable to at least one a base and a fluid connector connectable to the base, and an outer shield fixedly connected to the opposing end the needle and displaceable relative to the inner shield between a first position, in which the sharpened end of the needle is exposed outside the inner shield, and a second position, in which the sharpened end of the needle is shielded by the inner shield. Interaction between portions of the inner and outer shields during or after proximal displacement of the outer shield from the first position to the second position automatically releases or permits release of the inner shield from connection to the at least one of the base and the fluid connector. | 10-23-2014 |
20140313052 | Near Field Telemetry Link for Passing a Shared Secret to Establish a Secure Radio Frequency Communication Link in a Physiological Condition Monitoring System - A physiological condition monitoring system (e.g., a continuous glucose monitoring system) includes a physiological condition meter and a physiological condition sensor. The physiological condition meter and the physiological condition sensor are be placed in proximity to exchange a secret key using a near field wireless link, which is used to encrypt data to secure a radio frequency (RF) wireless channel. | 10-23-2014 |
20140309557 | Biological Fluid Sampling Transfer Device and Biological Fluid Separation and Testing System - A blood separation and testing system for a blood sample is disclosed. The blood separation and testing system includes a blood sampling transfer device adapted to receive a blood sample, a blood separation device, and a blood testing device. The blood separation device is adapted to receive a portion of the blood sampling transfer device such that with the blood sampling transfer device received within the blood separation device and a rotational force applied to the blood sampling transfer device, a plasma portion of the blood sample is separated from a cellular portion of the blood sample. The blood testing device is adapted to receive a portion of the blood sampling transfer device to analyze the plasma portion of the blood sample and obtain test results. | 10-16-2014 |
20140309552 | Syringe with Breakable Plunger for Arterial Blood Gas Sample Collection - A fluid collection assembly and method for use thereof is provided including a barrel with a plunger rod slidably inserted is disclosed. The assembly and method are particularly useful in the collection of arterial blood. The plunger rod includes a proximal portion, a distal portion with a stopper, and a breakable connector between the proximal and distal portions. In use, the assembly is primed with a liquid anticoagulant, the breakable connection is broken, and a fluid sample is collected with the arterial pressure causing the distal portion of the plunger rod to travel in a proximal direction along the barrel and contact an annular flange extending within the barrel. After collection, a tip cap can be applied to the assembly to prevent any spillage of the fluid sample during handling, storage, and transportation. | 10-16-2014 |
20140308167 | Biological Fluid Sampling Transfer Device and Biological Fluid Separation and Testing System - A biological fluid sampling transfer device that is adapted to receive and separate a multi-component blood sample is disclosed. After separation, the biological fluid sampling transfer device is able to transfer a plasma portion of the blood sample to a point-of-care testing device. The biological fluid sampling transfer device of the present disclosure also provides a closed sampling and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with an anticoagulant. The biological fluid sampling transfer device is engageable with a blood testing device for closed transfer of a portion of the plasma portion from the biological fluid sampling transfer device to the blood testing device. The blood testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results. | 10-16-2014 |
20140306383 | Medical Access Device - An access device provides needleless access to patient fluid lines such as intravascular catheters. A septum assembly of the access device is formed from a frame integrally molded with a septum and provides access for a tubular portion, such as a male luer taper of a syringe, of a medical device. The frame of the septum assembly is bonded to the housing of the device, which minimizes axial and rotational movement between the septum and the housing, so that the access device properly operates through multiple uses. | 10-16-2014 |
20140306122 | AUTOMATED SET-UP FOR CELL SORTING - Apparatus and methods are described for automatically performing set-up steps for flow cytometry operations. The invention provides for the spatial determination of a flow stream and the subsequent automatic alignment of analysis devices and/or collection vessels. The automatic determination of flow stream properties provides for the automatic configuration flow cytometer parameters. | 10-16-2014 |
20140303568 | Intravenous Tubing Set Modified for In-Line Catheter Flushing - An intravenous tubing set is provided having a coupling component for accessing a source of flush solution; a flush chamber; a first IV tubing for delivering saline solution from the source of flush solution to the flush chamber; a first flow control device disposed in the tubing between the source of flush solution and the flush chamber to control the flow of flush solution into the flush chamber; a second IV tubing for delivering flush solution to a patient catheter; and a second flow control device disposed in the second tubing between the flush chamber and the patient catheter. | 10-09-2014 |
20140302533 | ADVANCED DETECTION OF SEPSIS - The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject. | 10-09-2014 |
20140290341 | Detection of a Compromised Flow Line in a Laboratory Instrument - Provided herein are systems and methods for detecting a compromised flow line in a laboratory instrument. In one embodiment, for example, the system includes: (1) a wash station in fluid communication with a sample probe; (2) a fluid line coupled to the wash station to withdraw fluid from the wash station and deliver the fluid to a waste tank; and (3) a vacuum transducer, coupled to the fluid line, to measure vacuum pressure per unit time within the fluid line. The vacuum pressure per unit time is then used to detect a compromised flow line (e.g., a clog, occlusion, opening, etc. in the flow line). | 10-02-2014 |
20140288498 | Dual Chamber Passive Retraction Needle Syringe - Embodiments of a retractable syringe assembly are provided that include a single syringe barrel configuration and dual syringe barrel configuration. In one or more embodiments, the assemblies include a barrel having a dividing wall to divide the chamber to define a fluid chamber having a first cross-sectional width for retaining fluid and a needle chamber for housing a needle hub assembly. The assemblies include a projection extending radially outwardly from the plunger rod to interact with a ramped portion of the dividing wall to cause the needle cannula to retract and be housed within the needle chamber. | 09-25-2014 |
20140276462 | MULTIPLE-USE INTRAVENOUS CATHETER ASSEMBLY SEPTUM AND SEPTUM ACTUATOR - The present invention relates to a multiple-use intravenous (IV) catheter assembly septum and septum actuator. In particular, the present invention relates to an IV catheter assembly having a stationary septum actuator and a blood control septum, wherein the blood control septum is configured to slide within a catheter adapter of the IV catheter assembly between a compressed state and an uncompressed state. When in the compressed state, a slit of the blood control septum is opened and the septum comprises stored compressive potential energy. When the septum is released from the compressed state, the stored compressive potential energy is release and the blood control septum is restored to its original shape, thereby closing the septum's slit. | 09-18-2014 |
20140276449 | Syringe With Disinfecting Tip Feature - Syringe assemblies comprising a disinfecting reservoir collar to ensure adherence to aseptic techniques for use in flush procedures for vascular access devices (VAD's) are described. Also described are methods of disinfecting vascular access devices. | 09-18-2014 |
20140276219 | Placental and Cord Blood Collection Device with Safety - A novel blood collection device is described to secure a needle in place in a placenta or umbilical cord to prevent needle stick before, during, and after cord blood collection procedure. | 09-18-2014 |
20140262923 | PACKAGE FOR MEDICAL PRODUCT - A package for a multi-component medical device is disclosed. The package includes a bottom portion with cavities providing individual access to different components of the medical device, thereby enabling a user to remove components from the package in any order without disturbing the remaining component or components. The package also includes a barrier affixed to the bottom portion for sealing the package. | 09-18-2014 |
20140257249 | Syringe - IV Access Locking Device - A safety device is described wherein drug delivery systems and methods involve associating unique keys to patients that prevent the interconnection between a drug delivery device and non-complimentary patient key. Medication in a drug delivery device intended for a patient may only be accessed via a particular unique key associated with the intravenous access device of that patient. | 09-11-2014 |
20140257234 | BLOOD CONTROL CATHETER WITH ANTIMICROBIAL NEEDLE LUBE - An antimicrobial lubricant applied to an outer surface of an introducer needle as part of a catheter assembly device. The catheter assembly device further includes a blood control septum having a slit through which the introducer needle is threaded. The antimicrobial lubricant is squeegeed, or removed from the outer surface of the introducer needle as the needle is removed from the slit following catheterization. The removed antimicrobial lubricant forms a deposit on the septum at a location proximate to the slit, thereby preventing colonization and growth of pathogens on the septum and other adjacent components and surfaces of the catheter assembly device. | 09-11-2014 |
20140256580 | ASSAY FOR DETECTING CLOSELY-RELATED SEROTYPES OF HUMAN PAPILLOMAVIRUS (HPV) - A real time Taq-Man PCR assay for detecting multiple serotypes of human papillomavirus (HPV) wherein the number of serotypes detected exceeds the number of colorimetric channels for detection. A biological sample is combined with three oligonucleotide primer/probe sets such that the probes and primers anneal to a target sequence. Each primer/probe set is at least preferential for a specific serotype of an organism. The first and second primer/probe sets are degenerate with respect to each other. The third primer/probe set is not degenerate with respect to the first and second primer/probe sets and discriminates for a third serotype. The third primer/probe set has a signal moiety that emits signal at a wavelength that is the same or different from the wavelength emitted by the signal moiety of the degenerate primer/probe set probes. The target sequences, if present, are amplified and detected. | 09-11-2014 |
20140251847 | CONTAINER FOR INJECTION DEVICE WITH INJECTION NEEDLE - With the subject invention, a container for an injection device with an injection needle is provided. The container includes a body having a compartment formed therein to accommodate the injection device in both a pre-use and a post-use condition. The body defines a first opening through which the injection device in its pre-use condition may be accessed, and the body defines a second opening into which the injection device may be directed in its post-use condition. A closure is provided for closing the first opening. The container also includes a retainer for retaining the injection device in the container in its post-use condition preventing access to the injection needle after the injection device has been used to administer an injection. Advantageously, the container of the subject invention provides not only a pre-use packaging for the injection device, but also a post-use sharps container for the injection device. | 09-11-2014 |
20140251837 | ELECTRODE LAYOUT FOR BLOOD TEST SENSOR STRIP - An improved electrode layout for a continuous strip sensor is provided which reduces misalignment of the electrodes with the contacts which read the position of the strip. Better contact with the electrodes reduces or eliminates transient signals between stop positions of the sensor strip. | 09-11-2014 |
20140251804 | ELECTRODE LAYOUT FOR BLOOD TEST SENSOR STRIP - An improved electrode layout for a continuous strip sensor is provided which reduces misalignment of the electrodes with the contacts which read the position of the strip. Better contact with the electrodes reduces or eliminates transient signals between stop positions of the sensor strip. | 09-11-2014 |
20140249502 | Single Step Removal of Cannula Guard and Adhesive Liner in Medical Device - A medical device includes a body and a cannula extending from the body, for insertion into a patient's skin. The medical device also includes a guard covering the cannula, an adhesive for securing the medical device to the patient's skin, and an adhesive liner covering the adhesive. The guard is connected to the adhesive liner to enable conjoint and at least partial removal of the guard and the adhesive liner. | 09-04-2014 |
20140242610 | Methods and Compositions for Cytometric Detection of Rare Target Cells in a Sample - The present disclosure provides cytometric methods for the detection of rare target cells in a sample. In certain aspects, the methods and compositions may facilitate the detection of rare target cells, such as circulating tumor cells (CTCs), in a biological sample such as blood. Aspects of the methods include contacting the sample with first and second binding members that specifically bind to a marker of the rare target cell, and cytometrically assaying the sample for the presence of cells comprising bound first and second binding members to detect the rare target cell in the sample. Also provided are systems, compositions, and kits for practicing the subject methods. | 08-28-2014 |
20140238930 | Density Phase Separation Device - A mechanical separator for separating a fluid sample into first and second phases is disclosed. The mechanical separator includes a float having a first portion and a second portion, a ballast circumferentially disposed about a section of the float, and a deformable bellows defining an open passageway extending between a first end and a second end. The ballast is longitudinally moveable with respect to the float and engaged with the deformable bellows between the first end and the second end. At least a portion of the float is transitionable from a restraint position to a sealed position through the first end of the bellows. The first portion of the float can be positioned within the interior of the deformable bellows in the restraint position, and the first portion of the float can be positioned at an exterior location longitudinally displaced from the deformable bellows in the sealed position. | 08-28-2014 |
20140234838 | SQUARE WAVE THERMAL CYCLING - Embodiments disclosed herein relate to methods and systems for analysis of melting temperatures, and particularly to analysis of duplex nucleic acids. | 08-21-2014 |
20140220552 | BLOOD COLLECTION DEVICES CONTAINING CONTACT PATHWAY INHIBITION ADDITIVES - Disclosed are devices for collecting blood that contain an anti-coagulant and an additive that delays clotting by inhibiting the contact pathway for thrombin generation. The additive is a coagulation contact pathway inhibitor additive that is at least one of a Factor XI inhibitor, a Factor XII inhibitor, a kallikrein inhibitor and combinations thereof, each in an amount effective to mediate or suppress the contact pathway for thrombin generation. Methods of making and using the devices, and kits containing the devices, are also provided. | 08-07-2014 |
20140219889 | METHOD AND APPARATUS FOR DISPENSING DIAGNOSTIC TEST STRIPS - An apparatus for storing and dispensing a test strip includes a container configured to store a stack of test strips. The container maintains appropriate environmental conditions, such as humidity, for storing the test strips. An engaging member is disposed in the container and is adapted to contact one test strip of the stack of test strips. An actuator actuates the engaging member to dispense the one test strip from the container. Since one test strip is dispensed at a time, the remaining test strips are not handled by the user. Accordingly, the unused test strips remain free of contaminants such as naturally occurring oils on the user's hand. | 08-07-2014 |
20140216128 | METHODS AND SYSTEMS FOR ASSESSING SAMPLE BEHAVIOR IN A FLOW CYTOMETER - Methods and systems are disclosed for generating an entrainment factor in a flow cytometry sample. The methods comprise flowing a sample with a series of particles through the flow cytometer, detecting events and calculating an expected frequency of those events based on a distribution, such as a Poisson distribution, and measuring an observed frequency of particle events. An entrainment factor may be generated from a ratio of observed event frequency to expected event frequency. Further adjustment to the flow cytometer maybe performed based on the indicated entrainment factor such as adjusted sorting bias. | 08-07-2014 |
20140215976 | Package For Syringe - Packages comprising a syringe and a blister package are described. The blister package incorporates elements that allow one-handed opening. Also described are methods of removing a syringe from a package using only one hand. | 08-07-2014 |
20140213934 | Specimen Collection Container Having a Fluid Separation Chamber - A specimen collection container having a separation chamber includes a first chamber, a second chamber, and a valve located between the first chamber and the second chamber. In an open position, the valve permits fluid communication between the first chamber and the second chamber. In a closed position, the valve maintains fluid isolation between the first chamber and the second chamber. A fluid stream passes from the first chamber to the second chamber through the valve permitting a predetermined volume of fluid to pass from the first chamber to the second chamber. When the predetermined volume of fluid passes to the second chamber, the valve transitions from the open position to the closed position so that additional fluid of the fluid stream received by the first chamber is maintained in the first chamber in fluid isolation from the predetermined volume of fluid contained in the second chamber. | 07-31-2014 |
20140206088 | UNITIZED REAGENT STRIP - The embodiments disclosed herein relate to unitized reagent strips for holding and transporting reagents and materials used in automated sample preparation and/or processing for biological and or chemical assays. | 07-24-2014 |
20140205996 | DISSOLVABLE FILMS AND METHODS INCLUDING THE SAME - A method includes providing a container, introducing a substance into the container, and introducing a readily dissolvable film into the container such that the dissolvable film overlies the substance within the container. An alternative method includes providing a container, providing a readily dissolvable film, the film comprising a substance carried by the film, and introducing the film into the container. | 07-24-2014 |
20140200547 | Method for Altering Drug Pharmacokinetics Based on Medical Delivery Platform - A method for directly delivering whereby a substance is introduced into an intradermal space within mammalian skin which involves administering the substance through at least one small gauge hollow needle having an outlet with an exposed height between 0 and 1 mm. The outlet is inserted into the skin to a depth of between 0.3 mm and 2 mm such that the delivery of the substance occurs at a depth between 0.3 mm and 2 mm. | 07-17-2014 |
20140193819 | METHODS AND COMPOSITIONS FOR MODULATION OF AMPLIFICATION EFFICIENCY - Provided herein are methods and kits for modulating the amplification efficiency of nucleic acids, which are useful in multiplex reactions where the amplification efficiency of one or more nucleic acids in the mixture are desired to be modulated relative to one or more other nucleic acids. Embodiments relate to molecular diagnostics, including detecting sequence variants, such as SNPs, insertions deletions, and altered methylation patterns, as well as the modulation of the amplification efficiency of internal control sequences to provide more accurate control sequences for amplification reactions. | 07-10-2014 |
20140188046 | Pen Needle Assembly For Delivering Drug Solution - In one aspect, a pen needle assembly is provided herein which includes a hub, and a needle fixed to the hub, the needle having proximal and distal ends with a lumen extending therebetween. The needle extends distally from the hub to define an exposed length between the distal end of the needle and the hub in the range of about 5.0 to 9.0 mm. The hub defines a post formed about the needle, the post having a distally-facing first skin engaging surface. The exposed length of the needle extends distally from the first skin engaging surface. The hub also defines a distally-facing second skin engaging surface which at least partially circumscribes the first skin engaging surface. The second skin engaging surface being located proximally of the first skin engaging surface. Advantageously, a pen needle assembly is provided having two skin engaging surfaces which provide stability in achieving subcutaneous injections. | 07-03-2014 |
20140180048 | SYSTEM AND METHOD FOR USING MULTIPLE SENSOR CALIBRATION METHODS - The present invention relates to a system and method for improving glucose sensor accuracy by utilizing multiple calibration methods and selecting the most accurate method depending on a consensus glucose concentration estimate. Embodiments of the present invention comprise the steps of performing at least one in vivo update of surrounding glucose to acquire glucose values; calculating multiple updated calibration estimates using the updated glucose values; calculating an initial consensus glucose estimate from sensor output using each updated calibration estimate; applying a smooth crossover function to the multiple calibration estimates based on the value of the initial consensus glucose estimate; and adding weights to the multiple calibration estimates to acquire a consensus glucose estimate. | 06-26-2014 |
20140178928 | METHOD AND APPARATUS FOR AUTOMATED STAINING OF BIOLOGICAL MATERIALS - Various embodiments of the present invention provide methods and systems for optimally staining biological samples for analysis. In one embodiment, images of a sample are recorded before and after the application of a staining reagent and a decolorization reagent. A difference image is then generated based at least in part on a comparison of the images of the sample recorded before and after the application of the staining and decolorization reagents. Application parameters of the staining and decolorization reagents are then corrected based at least in part on the difference image such that the reagents may be optimally reapplied to generate a final image of the sample that may enable a user to better differentiate at least one target of interest in the sample. In one example, embodiments of the present invention allow for the generation of images that show only Gram-positive bacteria or only Gram-negative bacteria. | 06-26-2014 |
20140171904 | DISPOSABLE PEN NEEDLE WITH RE-USE PREVENTION FEATURES - A pen needle ( | 06-19-2014 |
20140165505 | Low Cost Medical Needle Container and Manufacturing Methods Therefor - Packaging is disclosed for a medical needle, such as a pen needle, having a hub with a patient end of the needle protruding from a distal end thereof. The packaging includes a tube having a first closed end into which the patient end of the needle is inserted so that the hub contacts an interior of the tube, a second closed end enclosing a proximal end of the hub, and a circumferential region disposed between the proximal end of the hub and the second closed end for opening the package to expose the proximal end of the hub. | 06-19-2014 |
20140163523 | Folding Inserter For Drug Delivery Infusion Set - An infusion set ( | 06-12-2014 |
20140163477 | End of Injection Indicator for Injection Pen - A medication injection pen ( | 06-12-2014 |
20140158212 | DUAL FEEDBACK VACUUM FLUIDICS FOR A FLOW-TYPE PARTICLE ANALYZER - The present invention relates to a vacuum-driven fluidic system for a flow-type particle analyzer. The system includes a vacuum pump which creates a pressure drop downstream of the flow cell, which pulls sheath fluid and sample fluid through the flow cell. A variable-resistance fluidic resistor is configured to control the ratio of sample fluid flow to sheath fluid flow. Dual feedback circuits, one configured to modulate the vacuum pump power in response to the pressure drop across the flow cell, referred to as the dynamic pressure drop, and a second configured to modulate the vacuum pump power in response to the pressure drop created by the vacuum pump relative to ambient pressure, referred to as the static pressure drop, are used to automatically control the system. The present invention enables adjustment of the sample fluid flow rate while maintaining a constant total fluid flow through the flow cell, and further, enables pausing the system without significant fluctuations in the vacuum. | 06-12-2014 |
20140155826 | Thumb Press Frangible Feature for Re-Use Prevention - Syringe assemblies having a passive disabling system to prevent reuse are provided. According to one or more embodiments, the syringe assembly comprises a barrel, plunger rod and detachable thumb press wherein the plunger rod further comprises flexible locking petals that lock the plunger rod within the barrel and one or more frangible connection or break point at the proximal end of the plunger rod disposed either inside the thumb press or immediately adjacent to the thumb press to separate the thumb press from the main body of the plunger rod when a user applies sufficient proximal force to the plunger rod after it has been locked within the barrel. | 06-05-2014 |
20140148781 | Methods and Apparatus for Disinfecting and Reflux Prevention Flush Syringe Assembly - Embodiments of the invention are directed to flush syringe assemblies comprising an integrated contamination-prevention device integrated with device connector flushing positioned so that the practitioner cannot forget to apply disinfectant. The flush syringe assemblies comprise a barrel with an elongate plunger rod disposed therein and a cap comprising a passageway. The plunger rod includes a stopper of which at least a portion can be embedded in the passageway of the cap to form a plug in the cap. | 05-29-2014 |
20140148749 | GLUCOSE MANAGEMENT AND DIALYSIS METHOD AND APPARATUS - A process and apparatus are provided for managing and adjusting glucose levels in the blood of a patient during dialysis. The apparatus is a dialysis apparatus to treat patients with renal disease which includes a glucose scavenger to remove excess glucose from the blood before returning the blood to the patient and/or a device to increase blood glucose levels in the blood when the glucose level is below a threshold level. The glucose scavenger can include a glucose binding protein, boronic acid derivative, boronic ester derivative or mixture thereof bonded to the surface of a support such as a fiber bundle in a cartridge or the inner surface of tubing used in the apparatus. | 05-29-2014 |
20140135711 | PATIENT FLUID LINE ACCESS VALVE ANTIMICROBIAL CAP/CLEANER - Cap and cleaning devices antiseptically maintain patient fluid line access valves to minimize the risk of infection via catheters. The devices have a cap that may contain a dry pad impregnated with an antimicrobial agent. The cap covers the access portion of the access valve when not in use. The devices have a hood that contains a wet pad impregnated with a cleaning solution and, optionally, an antimicrobial agent. The wet pad cleans the access portion of the access valve prior to and optionally, after the access valve is utilized to access the patient fluid line. | 05-15-2014 |
20140135710 | PATIENT FLUID LINE ACCESS VALVE ANTIMICROBIAL CAP/CLEANER - Cap and cleaning devices antiseptically maintain patient fluid line access valves to minimize the risk of infection via catheters. The devices have a cap that may contain a dry pad impregnated with an antimicrobial agent. The cap covers the access portion of the access valve when not in use. The devices have a hood that contains a wet pad impregnated with a cleaning solution and, optionally, an antimicrobial agent. The wet pad cleans the access portion of the access valve prior to and optionally, after the access valve is utilized to access the patient fluid line. | 05-15-2014 |
20140135696 | Pen Needle Assembly For Preventing Under-Torquing and Over-Torquing Of Pen Needle - A pen needle hub and cover for a pen needle assembly that provides tactile and/or audible indicia of proper attachment between the hub of the pen needle and the pen is provided. Such indicia substantially prevent under- and over-torquing of the pen needle. The tactile indicia may include a user sensing a wave of a torque of peak value followed by a torque of lesser value. | 05-15-2014 |
20140135652 | Passive Double Drive Member Activated Safety Blood Collection Device - A shieldable needle device including a drive member is disclosed. The drive member is extendable between a biased position and an extended position for moving a tip guard from an first position to a second position in which the tip guard shields a distal end of the needle cannula. The shieldable needle device includes a pair of wings extending laterally from opposing sides of the hub that are movable between a laterally extending position and a dorsal position. With the wings in the dorsal position, the wings retain the drive member in the biased position thereby maintaining the tip guard in the first position. Movement of the wings from the dorsal position to the laterally extending position releases retainment of the drive member. A second drive member may be included. | 05-15-2014 |
20140134617 | PROCESS CONTROLS FOR MOLECULAR ASSAY - A full process control for use with a molecular assay and a method of determine the efficacy of the molecular assay. A full process control can include a fixed cell, and specifically can include a fixed vegetative cell. A method of determining the efficacy of a molecular assay can include providing an internal control, mixing the internal control with a sample, lysing the internal control and the sample, and detecting the lysis product. The full process control and/or the internal control can be | 05-15-2014 |
20140110448 | SHARPS CONTAINER - A process of manufacturing a sharps container and a method of storing needles are disclosed. The sharps container utilizes a blocking member which does not interfere with a needle being inserted into the sharps container, and a latch mechanism which does not require a protruding tab. The latch mechanism requires at least a dual action to open the sharps container, and limits the movement required for opening the sharps container. | 04-24-2014 |
20140110297 | "Medical Articles Coated With Organopolysiloxane Containing a Protein Solution" - This invention relates to methods for evaluating or inhibiting the aggregation of a protein in an aqueous suspension including organopolysiloxane and medical articles coated with organopolysiloxane containing a protein solution including sugar and non-ionic surfactant. | 04-24-2014 |
20140107586 | SAFETY PEN NEEDLE ASSEMBLY HAVING SHIELDING FOR PATIENT AND NON-PATIENT ENDS - A safety pen needle assembly is provided herein which includes a hub and a needle fixed to the hub. Further, a first shield is provided, along with a second shield which has a biasing element disposed to urge the second shield proximally towards a proximal end of the needle. The assembly further includes a releasable retaining assembly for releasably retaining the second shield in an initial position against the force of the biasing element. A predetermined extent of movement of the first shield causes the retaining assembly to release the second shield. With the second shield being released, the second shield is urged proximally by the biasing element to a second position where the second shield covers the proximal end of the needle. Advantageously, an assembly is provided which allows for passive activation of a shield on a non-patient end of a pen needle assembly by a patient-end shield. | 04-17-2014 |
20140106676 | CASE WITH EMBEDDED ELECTRONICS TO PROVIDE INTERFACE BETWEEN GLUCOSE SENSOR AND SMARTPHONE - A mobile phone case with an embedded wireless interface for enabling communications between a continuous glucose monitoring (CGM) sensor and a mobile phone is described. The mobile phone case includes an autonomous battery and an autonomous alarm speaker for enabling communication with a CGM sensor in situations where the mobile phone is unavailable. | 04-17-2014 |
20140100544 | INFUSION SET WITH SAFETY DEVICE - An infusion set includes a base with a rigid piercing cannula or a soft catheter and rigid introducer needle. The infusion set also includes a line set with a fluid connector. The base and line set are configured such that the fluid connector can be used as a protector for the piercing cannula or the soft catheter, either before the device is attached to a user, or after the device is detached from the user, or both. | 04-10-2014 |
20140095567 | RAPID SYNDROME ANALYSIS APPARATUS AND METHOD - In a computer; a computer readable medium for providing rapid syndrome analysis includes instructions for measuring a plurality of CUSUMs simultaneously and generating CUSUM data in response to an observed value. It also includes instructions for comparing the CUSUM data with a predetermined plurality of threshold values and instructions for generating a signal when the CUMSUM data exceeds any of the plurality of threshold values by a predetermined amount. | 04-03-2014 |
20140094776 | INJECTION DEVICE WITH AUTOMATED SUBSTANCE COMBINING FEATURE - An injection device for automatically combining two substances, including a body and a cartridge displaceably disposed within the body having a first chamber for containing a first substance, a second chamber for containing a second substance, a first stopper displaceably disposed within the cartridge separating the first and second chambers, a second stopper displaceably disposed within the cartridge defining an end of the second chamber. The device also includes a needle hub displaceably disposed within the body having threads thereon for connecting a pen needle to the injection device. The device additionally includes a plunger displaceably disposed within the body, a biasing member, a sleeve, biased by the biasing member and communicating the bias to the plunger, and an activation button radially displaceable with respect to the body to selectively release the sleeve to drive the plunger and automatically mix the first and second substances. | 04-03-2014 |
20140094765 | INJECTION DEVICE WITH PLURAL DOSAGE SETTING WINDOWS - An injection device ( | 04-03-2014 |
20140093949 | ABSORBANCE SPECTRUM SCANNING FLOW CYTOMETRY - The present invention provides systems and methods for analyzing the excitation spectra of fluorescent particles in a flowing stream. The system uses a white light laser and color separation optics to provide a spatially-distributed, continuous color-spectrum excitation light system that is used to illuminate a region of a flowing stream. A particle that passes through the detection region traverses the full dispersed spectrum of excitation light, and the fluorescence emissions from the particle are continuously measured as it passes through the detection region. The measured fluorescence emissions at each wavelength of excitation light, which changes through full spectrum of the excitation light as the particle passes through the detection region, provides the excitation spectrum of the particle. | 04-03-2014 |
20140088550 | PERPENDICULAR INFUSION SET AND DISPOSABLE INSERTER - An infusion set is disclosed that includes an inserter including an inserter housing having at least one flexible arm for holding an infusion set in a single axial position prior to insertion of at least a portion of a cannula of the infusion set, the inserter housing having a surface for contacting the patient's skin. The inserter also includes a movable plunger disposed within the inserter housing for releasing the infusion set from the inserter housing, impacting the infusion set, and imparting momentum to the infusion set to insert the cannula into the patient's skin. The inserter additionally includes a biasing element biasing the plunger toward the activated position. | 03-27-2014 |
20140088549 | Angled Inserter For Drug Infusion - An infusion set adapted to be secured to a skin surface includes a fixed base member and a movable slide member. The fixed base member is connectable to the skin surface. The movable slide member has a needle or cannula connected thereto and is movable relative to the fixed base member. The movable slide member is movable from a first position in which the needle or cannula is not exposed externally of the fixed base member to a second position in which the needle or cannula is exposed externally of the fixed base member. The movable slide member is locked to the fixed base member in the second position. | 03-27-2014 |
20140088512 | SINGLE-USE INJECTOR OF LOW COST - An injection device ( | 03-27-2014 |
20140088509 | Infusion Device with Automatic Insertion and Introducer Needle Retraction - An infusion device ( | 03-27-2014 |
20140081239 | INJECTION DEVICE - An injection device ( | 03-20-2014 |
20140081238 | METHOD OF RECONSTITUTING A SUBSTANCE USING AN INJECTOR DEVICE - The present invention is directed to an automatic reconstitution drug delivery device. The inventive device effects simple and automatic reconstitution of a dry drug. To effect reconstitution, a user displaces a release button which causes first and second chambers of a drug cartridge to communicate, resulting in automatic mixing of a diluent and dry drug to effect reconstitution of the dry drug. The user then simply sets the dose volume using a dose-setting mechanism, and administers the injection in a manner typical of self-injection drug delivery devices. Whole or partial automatic priming can be also achieved by the device. | 03-20-2014 |
20140080164 | METHODS AND COMPOSITIONS FOR THE DETECTION OF BETA-LACTAMASES - Presented herein are methods and compositions for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum beta-lactamases (ESBLs). The methods presented herein include methods that permit the detection of the presence of specific beta-lactamases in bacterial samples within as few as 2 to 10 minutes. | 03-20-2014 |
20140074064 | INTRADERMAL DELIVERY DEVICE INCLUDING A NEEDLE ASSEMBLY - A drug delivery device including a needle assembly facilitates making intradermal injections using a variety of drug container types such as a syringe. A hub supports the needle while a limiter surrounds the needle. The limiter includes a skin engaging surface that is adapted to be received against the skin of an animal to be intradermally injected. A forward end of the needle extends beyond the skin engaging surface a selected distance to limit a depth that the needle penetrates into the animal's skin. | 03-13-2014 |
20140074039 | MEDICAL INJECTOR WITH COUPLED BODY PORTIONS - A medical injector is provided herein which includes first and second body portions each having a longitudinal axis and configured to couple at a coupling. The medical injector also includes an axially-displaceable plunger; biasing element for advancing the plunger a predetermined distance; and, a releasable retainer for releasably retaining the plunger in a first state against the force of the biasing element. In an initial state, the axes of the first and second body portions are not aligned and the plunger is in the first state. In a coupled state, the axes of the first and second body portions are axially aligned, and the releasable retainer releases the plunger, thereby allowing the biasing element to advance the plunger the predetermined distance. Advantageously, the subject invention provides a medical injector having an automated plunger drive which is triggered upon assembly of the pen injector, thereby minimizing premature or failed activations. | 03-13-2014 |
20140074037 | LUER SECUREMENT DEVICE - A Luer securement device comprising a flexible hood that is configured to attach to the surface of a patient, the flexible hood further having a Luer adapter for receiving a catheter inserter and/or a fluid line. The Luer securement device further includes a wedge seal that is positioned within the Luer adapter and is configured to receive a base portion of a catheter during a catheterization procedure. Once the base of the catheter is seated within the wedge seal, a proper insertion depth of the catheter into the patient is achieved. | 03-13-2014 |
20140074033 | Insulin Infusion Set - An insulin infusion set ( | 03-13-2014 |
20140074032 | INTRAVENOUS CATHETER INSERTER - An intravenous catheter inserter device comprising a catheter threader body on which is slidably attached a septum activator, a catheter threader, and a needle hub. Some embodiments further include a safety bar that is configured to assist in coordinating the movement of the various components of the device during a catheterization procedure. In general, the septum activator provides a pathway through a septum of a Luer adapter. The Luer adapter comprises a wedge seal that is configured to receive a base portion of a catheter that is inserted into the Luer adapter by the catheter threader. Accordingly, the device of the present invention simultaneously accesses the vasculature of a patient while assembling the catheter into the Luer adapter. The final configuration provides an integrated unit that is attached to the patient and in fluid communication with patient's vascular system. | 03-13-2014 |
20140074031 | INTEGRATED CATHETER SECUREMENT AND LUER ACCESS DEVICE - A Luer securement device comprising a Luer adapter having a septum and a catheter hood, the Luer adapter further having a wedge seal for receiving a base portion of a catheter. The Luer securement device further includes an inserter body in which is slidably housed a catheter threader having a probe which is configured to advance a base portion of a catheter through the septum thereby seating the base portion of the catheter into the wedge seal of the Luer adapter as a tip portion of the catheter is inserted into a patient. The catheter threader further includes a needle adapter having a needle which is threaded through the probe and the catheter to assist in inserting the catheter into the patient. Following insertion of the catheter, the catheter threader is retracted within the inserter body thereby withdrawing the needle from the catheter and shielding a sharpened tip of the needle within at least one of the inserter body and the catheter threader. The inserter body is then detached from the Luer adapter and discarded. | 03-13-2014 |
20140074028 | One-Piece Molded Catheter and Method of Manufacture - A one-piece catheter ( | 03-13-2014 |
20140066611 | OLIGONUCLEOTIDE PRIMERS, PROBES, KITS AND METHODS FOR DETECTION OF CYTOMEGALOVIRUS - Amplification primers and methods for specific amplification and detection of a CMV target are disclosed. The primer-target binding sequences are useful for amplification and detection of the CMV target in a variety of amplification and detection reactions. | 03-06-2014 |
20140058360 | Self-Contained Inserter For Drug Delivery Infusion Set - An infusion set ( | 02-27-2014 |
20140058353 | Subcutaneous Infusion Device - An infusion system having an integrated inserter and infusion set ( | 02-27-2014 |
20140058336 | BLOOD CONTROL IV CATHETER WITH ANTIMICROBIAL PROPERTIES - A medical device is presented, which includes a fluid pathway and a septum slidably housed within the fluid pathway. The septum can be opened by a septum actuator disposed in a fixed position within the fluid pathway. In some examples, both the septum actuator and the septum have at least one surface exposed to the fluid pathway. An anti-pathogenic material can be applied to these surfaces. | 02-27-2014 |
20140058045 | Novel Amphiphilic Graft Copolymers - A novel amphiphilic graft copolymer is described. A process to make amphiphilic graft copolymers via grafting either poly(ethylene oxide) or polylactide side chains onto an EVA platform using oxo-anion ring-opening polymerization chemistry is also described. Polyethylene or polypropylene based graft copolymers are prepared starting from poly(ethylene-co-vinyl acetate) or maleic anhydride grafted isotactic polypropylene respectively. The amphiphilic character will result from the incorporation of hydrophilic poly(ethylene oxide) (PEO) side-chains. Various applications of the novel amphiphilic graft copolymer are also described including, but not limited to, thermoplastic elastomer, films, fibers, fabrics, gels, breathable packaging materials, additive for biodegradable system, surfactant, antistatic additives, polymer compatibilizers, phase transfer catalysts, solid polymer electrolytes, biocompatible polymers, or incorporation into the materials listed above. | 02-27-2014 |
20140053871 | SYSTEMS AND METHODS TO MONITOR PROPER DISINFECTION OF NEEDLELESS CONNECTORS - A device and method for disinfecting a needleless connector, the device including a housing comprising a hub rotationally coupled to a motor, the motor being operably connected to a power source, the hub further comprising a receptacle configured to receive a cleaning head, wherein the device is configured to detect achievement of one or more minimum thresholds which are recommended to achieve proper disinfection of the needleless connector. Various devices and methods are further provided to permit tracking and reporting of disinfection events. | 02-27-2014 |
20140052096 | PUMP ENGINE WITH METERING SYSTEM FOR DISPENSING LIQUID MEDICATION - An infusion pump system is disclosed for dispensing liquid medication, such as insulin. The infusion pump system includes a first reservoir for storing liquid medication, a first fluid driver for exerting pressure on the first reservoir, a second reservoir for storing liquid medication, and a second fluid driver for exerting pressure on the second reservoir. One or more valves are used to permit flow of liquid medication from the first reservoir to the second reservoir, and to permit flow of liquid medication from the second reservoir to an infusion site. Each of the valves is selectively opened or closed to fill the second reservoir with liquid medication from the first reservoir and to dispense liquid medication from the second reservoir to the infusion site. A controller and one or more sensors are used to monitor and control the system. | 02-20-2014 |
20140052076 | Sealing Members, Articles Using the Same and Methods of Reducing Sticktion - The present invention provides rubber sealing members having an exterior surface adapted to sealingly engage an inner surface of a chamber of a medical device, the exterior surface of the sealing member having a coating thereon prepared from a curable composition including: (a) a first organopolysiloxane having at least two alkenyl groups; and (b) a second organopolysiloxane having at least two pendant hydrogen groups, the second organopolysiloxane being different from the first organopolysiloxane, wherein at least one of the first organopolysiloxane, the second organopolysiloxane or an optional third organopolysiloxane of the curable composition comprises a fluoro group. | 02-20-2014 |
20140052074 | Medical Devices For Blood Reflux Prevention And Methods Of Use - Described is a catheter patency maintenance device comprising of a flush syringe, an elongate plunger rod with a stopper slidably positioned within the barrel, a cap, disinfectant and a valve movable between an open position and a closed position. The valve may include a valve stem and/or openings in the valve to permit fluid flow. Methods of using the flush syringe assemblies are also described. | 02-20-2014 |
20140052073 | Controlled Release Structure for Attaching Medical Devices - A medical device for use with a fluid transfer device includes a hub having an open proximal end with a frusto-conically-shaped cavity therein, a distal end and a passageway therethrough. The cavity is part of the passageway. A release element in the passageway of the hub is positioned to block fluid-tight engagement of the frusto-conically-shaped tip with the cavity of the hub. Structure is provided to release at least part of the release element, upon application of a proximally directed force on the hub, to allow the abrupt fluid-tight engagement of the tip and the cavity in the hub. | 02-20-2014 |
20140052022 | Flashback Blood Collection Needle - A needle assembly includes a transparent or translucent housing with a fluid inlet and outlet end, a flashback chamber, and a venting mechanism therebetween. The venting mechanism includes a blocking member to control the fluid flow in the venting mechanism so that it flows along the longest path through the vent. Substantially axially aligned inlet and outlet cannulas extend from the housing and communicate with the chamber. A sealable sleeve covers the external end of the outlet cannula. Relative volumes of the cannulas, the chamber, and the sleeve are selected to provide rapid reliable flashback indicative of venous entry with an internal vent positioned within the housing to divide the interior into first and second chambers, with the second chamber being adapted to maintain a negative pressure therein relative to the external environment so as to inhibit leakage of blood from the needle tip on withdrawal from the patient. | 02-20-2014 |
20140052021 | REMOVABLE FLASH CHAMBER - A needle hub and catheter assembly are disclosed herein. The needle hub includes an introducer needle having a lumen extending therethrough. A needle hub is coupled to a proximal end of the introducer needle. A flash chamber is removably coupled to the needle hub or the introducer needle. An interior of the flash chamber is in fluid communication with the lumen of the introducer needle when the flash chamber is coupled to the needle hub or the introducer needle. As such, the flash chamber can collect a sample of blood that can be accessed when the flash chamber is removed. In some instances, the blood can also be dispensed from the flash chamber into a test strip or other testing device. | 02-20-2014 |
20140051064 | Cell Sorter System and Method - Provided herein are improved cell sorter systems and methods. Such systems and methods provide a self-stabilizing sorter jet to automate calibration, and address the issue of drift in cell sorting systems. The systems and methods presented make it possible to determine and set the charge delay interval automatically with circuitry in the cell sorter. These circuits can set, monitor, and adjust the time delay continuously, allowing for a completely automatic, autonomous, turn-key, self-stabilizing sorter jet. | 02-20-2014 |
20140046268 | Multiple Use Disposable Injection Pen - A medication injection pen ( | 02-13-2014 |
20140046258 | SYSTEMS AND METHODS FOR PROVIDING A FLUSHABLE CATHETER ASSEMBLY - A flushable catheter assembly having features to enable selective activation of fluid flow through the catheter assembly is disclosed herein. A septum is placed within the catheter adapter of the catheter assembly and includes a pathway that is closed prior to being biased open via a septum activator also positioned within the catheter adapter. A plurality of air vent channels is interposed between the septum and the inner surface of the catheter adapter to permit “flashback” of blood during insertion of the catheter into a patient. The septum activator is advanced through the pathway of the septum as a coupler is attached to a proximal opening of the catheter adapter. | 02-13-2014 |
20140039458 | Compact Spring Inserter For Drug Delivery Infusion Set - An infusion set ( | 02-06-2014 |
20140039453 | Subcutaneous Infusion Set With Side Port Fluid Connector - An infusion set preferably for use with an inserter is disclosed. The infusion set includes a septum cap that encapsulates an upper resilient septum and a lower resilient septum of a base, and includes at least one radial port to receive insertion of a blunt cannula when an extension set hub is engaged with the infusion set in a direction substantially parallel to the skin surface. The extension set hub is configured to provide a snap-fit engagement with the septum cap, wherein the blunt cannula of the extension set hub is guided through the radial port of the septum cap and penetrates the interface between the upper septum and the lower septum. The extension set hub and the septum cap can be rotated in a 360 degree manner about the base of the infusion set. | 02-06-2014 |
20140038259 | FLUIDIC IN-LINE PARTICLE IMMOBILIZATION AND COLLECTION SYSTEMS AND METHODS FOR USING THE SAME - Fluidic sorting systems configured to immobilize, and optionally concentrate and/or analyze, one or more particles within the system are provided. Aspects of the systems include a flow-through chamber and an immobilization component configured to immobilize, preferably reversibly, a particle within the flow-through chamber. Optionally, the systems include an analysis component configured to optically analyze an immobilized particle within the flow-through chamber. In certain aspects, the systems are configured to collect one or more particles from the flow-through chamber for subsequent analysis, experimentation, and/or use. Also provided are methods, components and kits for reversibly immobilizing, and optionally analyzing, one or more particles within a fluidic sorting system. | 02-06-2014 |
20140031793 | COMPACT SPRING INSERTER FOR DRUG DELIVER INFUSION SET - An infusion set ( | 01-30-2014 |
20140030754 | BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR - Disclosed are collection devices for collecting and stabilizing whole blood or a component thereof, which include a first end and a second end and at least one interior wall defining a reservoir, wherein the reservoir contains a stabilization agent that includes a lysophospholipase (LysoPLA) inhibitor. Also disclosed are methods for making and using the devices. | 01-30-2014 |
20140030710 | GARDNERELLA VAGINALIS ASSAY - The present invention relates to nucleic acid amplification assays for the detection of nucleic acid sequences of | 01-30-2014 |
20140018742 | Packageless Syringe Assembly with Sterilizable Fluid Path - Syringe assemblies comprising a first cap and a second cap to ensure sterilization of the fluid path without the need for external packaging are described. Also described are methods of sterilizing the fluid path of a syringe assembly. | 01-16-2014 |
20140018734 | Intradermal Delivery Device With Crenellated Skin Engaging Surface Geometry - An apparatus for delivering or withdrawing a fluid through at least one layer of the skin is provided. The device may include a body having a top face, a bottom face, a side edge and at least one channel. The bottom face includes a first surface area and a second surface area adjacent to and recessed at a first distance from the first surface area. The bottom face further includes at least one raised protrusion disposed on the second surface area. The protrusion has a height from the first surface greater than the first distance. At least one dermal-access member is provided in the protrusion and is in fluid communication with the channel to deliver or withdraw the fluid. | 01-16-2014 |
20140013718 | Package for Syringe - Packages comprising a syringe and a blister package are described. The blister package incorporates elements that allow one-handed opening. Also described are methods of removing a syringe from a package using only one hand. | 01-16-2014 |
20130338589 | Patch-Like Infusion Device - A system and method for a patch-like, self-contained substance infusion device which can be attached to a skin surface via an adhesive contact surface. A push button activation assembly can then be used to remove an interlock, allowing a disk or Belleville spring assembly to apply an essentially even and constant pressure to the contents of a fluid reservoir assembly. This allows the release of one or more spring-loaded patient needles into the skin surface, and establishes a fluid communication path between the patient needles and the pressurized fluid reservoir contents thereby delivering an infusion into the skin. The push button activation assembly further allows the release of one or more improved safety mechanisms after use. | 12-19-2013 |
20130337569 | SERS Nanotag Assays - Methods and systems for the use of Surface Enhanced Raman Scattering nanotags (SERS nanotags) to create homogeneous (no-wash), heterogeneous or sequence detection assay platforms. In certain embodiments the SERS nanotags are used in combination with magnetic particles. Multiplexed assay platforms are also disclosed. In certain embodiments, the assay is useful for clinical proteomics. Assay platforms suitable for use within a biological matrix, for example within whole blood or serum are also disclosed. The assay formats described herein may be used to detect any analyte of interest including but not limited to the detection of cells, viruses, bacteria, proteins, DNA, RNA, or small molecules in any type of biological (animal or plant kingdom) or environmental samples including but not limited to whole blood or serum, occult samples, urine, feces, air, drinking water, phage, any organism, multicellular clumps of cells, for example, cancer tissue homogenate. | 12-19-2013 |
20130330739 | Devices and Methods for Separating Magnetically Labeled Moieties in a Sample - Devices for separating magnetically labeled moieties in a sample are provided. Aspects of the devices include a magnetic field source, a first magnetic field guide having a wedge-shaped portion with an apex edge, and a second magnetic field guide having a wedge-shaped portion with an apex edge. The apex edge of the first magnetic field guide is aligned substantially across from and parallel to the apex edge of the second magnetic field guide, and the device is configured to separate magnetically labeled moieties from non-magnetically labeled moieties in the sample. Also provided are methods of using the devices, as well as systems and kits configured for use with the devices and methods. | 12-12-2013 |
20130330387 | ANTIMICROBIAL LUBRICANT COMPOSITIONS - Antimicrobial lubricant compositions are disclosed. The antimicrobial lubricant compositions are particularly useful in providing antimicrobial capability to a wide-range of medical devices. The compositions include an oil lubricant. Representative lubricants may include polydimethyl siloxane, trifluoropropyl copolymer polysiloxane, and a copolymer of dimethylsiloxane and trifluoropropylmethylsiloxane. The compositions include rheology modifiers as necessary. The compositions also include antimicrobial agents, which may be selected from a wide array of agents. Representative antimicrobial agents include of aldehydes, anilides, biguanides, bis-phenols, quaternary ammonium compounds, cetyl pyridium chloride, cetrimide, alexidine, chlorhexidine diacetate, benzalkonium chloride, and o-phthalaldehyde. | 12-12-2013 |
20130323120 | UV DISINFECTION SYSTEM FOR NEEDLELESS CONNECTOR - A device is presented for disinfecting needleless connectors. The device has a housing that contains a UV light source. The UV light source is operably connected to a power source. The housing has a receptacle configured to selectively receive a shield. The shield has an inner reflective chamber with an internal surface that reflects UV light. In use, the UV light source can illuminate a needleless connector inserted within the shield. | 12-05-2013 |
20130323117 | SYSTEMS AND METHODS TO MONITOR PROPER DISINFECTION OF NEEDLELESS CONNECTORS - A device and method for disinfecting a needleless connector, the device including a housing comprising a hub rotationally coupled to a motor, the motor being operably connected to a power source, the hub further comprising a receptacle configured to receive a cleaning head, wherein the device is configured to detect achievement of one or more minimum thresholds which are recommended to achieve proper disinfection of the needleless connector. Various devices and methods are further provided to permit tracking and reporting of disinfection events. | 12-05-2013 |
20130310808 | Flush Enhancing Male Luer Tip Design for Syringes and any Luer Connector - A luer connection device is disclosed having a housing including a side wall having an inside surface defining a lumen with a central axis, an proximal end, and a distal end including a male luer tip within the lumen having a central flow diverter extending outwardly from the central axis to direct a fluid to a circumferential dead space distal to the male luer tip. A luer connection device is also disclosed having a flow expansion channel disposed in the lumen tapering outward from the wall of tubular housing and partially extending along a longitudinal axis from the tip opening toward the base opening for increasing mixing and flow through a circumferential dead space in the fluid path distal to the male luer tip. | 11-21-2013 |
20130310764 | BLOOD CONTROL IV CATHETER WITH ANTIMICROBIAL PROPERTIES - A system and method is provided for applying an anti-pathogenic material to various surfaces of a medical device, wherein the method includes identifying various surfaces of the medical tests which include noncritical dimensions, and limiting the application of the anti-pathogenic material to those surfaces. Some aspects of the invention further include the application of an anti-pathogenic lubricant material to various parts or components of a medical device to reduce friction. | 11-21-2013 |
20130310751 | OVER-THE-NEEDLE INTRAVENOUS CATHETER ASSEMBLY WITH INTEGRATED INTRAVENOUS TUBING - An intravenous catheter device is provided which includes a catheter adapter having a fluid chamber, a needle adapter being slidably positioned within the fluid chamber, the needle adapter supporting a base of an introducer needle and a terminal end of a section of intravenous tubing such that a fluid pathway of the introducer needle is in fluid communication with a fluid pathway of the section of intravenous tubing. Following catheterization, the needle adapter is slid to a preferred proximal position whereby a sharpened tip of the introducer needle is shielded within a catheter of the intravenous catheter device, or a portion of the fluid chamber of the catheter adapter. When in the preferred proximal position, fluid communication between the catheter and a section of intravenous tubing is facilitated via the hollow body of the introducer needle. | 11-21-2013 |
20130296235 | CONTAINER AND METHOD FOR STORING A PHARMACEUTICAL AGENT - A container and method for storing a pharmaceutical agent are provided for enhancing the storage time. The storage time of the pharmaceutical agent is improved by reducing the loss of stabilizing agents in the pharmaceutical agent. The storage container is formed from a polyolefin that includes a stabilizing agent in an amount effective to reduce or inhibit the migration of stabilizing agents in the pharmaceutical agent. The polyolefin container is formed with a fatty acid amide such as erucamide for stabilizing insulin that contains m-cresol and/or phenol as stabilizing agents for the insulin. The fatty acid amide incorporated in the container inhibits and/or reduces the rate of migration of the m-cresol and/or phenol into the polyolefin to extend the storage life of the insulin. The container can be a syringe, such as a pre-filled syringe, a storage vial or the flow path of an infusion pump. | 11-07-2013 |
20130289493 | Dose Dividing Delivery Device - A simple method and device enabling a unit dose from a reservoir is provided. The dose is drawn into the reservoir and is then expelled from the device by depressing a plunger. The plunger has features which divide the dose into discrete intervals. As the plunger is moved during delivery, features on the plunger and features connected to a barrel interact to provide for intermittent stops to the delivery. Other aspects of the device provide for reduced dead space, safety and selective interconnection with other devices. Thus, the device divides the dose. | 10-31-2013 |
20130281972 | PASSIVELY SHIELDING NEEDLE ASSEMBLY WITH SKIN SENSOR - A shielding needle assembly is provided with a hub having a needle cannula with a puncture tip extending from a forward end thereof, and a shield member in telescoping association with the hub. A drive member biases the hub and the shield member away from each other for relative telescopic movement between a first position in which the puncture tip extends from a forward end of the shield member, and a second position in which the puncture tip is encompassed within the shield member. A pivoting lever maintains the hub and the shield member in the first position against the bias of the drive member with the needle cannula exposed for use. The lever is pivotable during contact with a patient's skin surface such as during venipuncture, thereby releasing the hub and the shield member from the first position and permitting the drive member to bias the hub and the shield member toward the second position. | 10-24-2013 |
20130274706 | MEDICAL INJECTOR WITH POST-AUTORECONSTITUTION DOSE SETTING AND AUTOPLUNGER DRIVE - A medical injector is provided herein having a body; a reservoir containing first and second mixable components; a stopper; a plunger disposed in the body; a spring disposed to advance the plunger; a first releasable retainer for releasably retaining the plunger in a first state against force of the spring; a first trigger for causing the first releasable retainer to release the plunger; a second releasable retainer for releasably retaining the plunger in a second state against force of the spring; and, a second trigger for causing the second releasable retainer to release the plunger. The spring causes the plunger to advance so that the stopper traverses at least a predetermined extent of advancement thereby causing mixing of the first and second mixable components. Advantageously, with the subject invention, a medical injector is provided which allows for autoreconstitution with subsequent dose setting and autoplunger activation being activated by separate triggers. | 10-17-2013 |
20130261565 | Angled Retracting Sheath for Safety Needle - A safety needle device having a housing, a retractable sheath, and a needle cannula. The retractable sheath includes a tubular portion that is slideably mounted about a portion of the housing to completely or partially encase the length of the cannula. The retractable sheath includes a sheath bevel at the distal end having a blunted or angled tip. The angled tip being configured to suitable injection angles and may be fixed or rotatable. The sheath bevel may include a skin-engaging contact surface at the distal end. The needle may be connected to a needle hub at the proximal end of the housing and includes a needle bevel at the distal end. The sheath bevel and needle bevel may be offset from each other. A safety needle device having a retractable sheath having a graduated injection depth gauge to indicate needle penetration is also disclosed. | 10-03-2013 |