Patent application number | Description | Published |
20140035695 | FREQUENCY AGILE HIGH POWER MICROWAVE GENERATOR - A Multi-Cycle Digital High Power Microwave (MCD-HPM) source includes a microwave transmission line (MTL) to which a plurality electrically charged thin film transmission lines (TFTL's) are connected by switches. The switches are activated in sequence to generate a square wave at a microwave output frequency. The activation signal is controlled by a free space time delay, which can vary the timing and/or routing of the activation signal by modifying at least one free space element, thereby adjusting the switch activation timing and varying the output frequency. In embodiments, the switches are photo-conducting switches, the activation signal is a laser beam, and the switch timing is varied by reorienting and/or repositioning mirrors and/or other elements in the free space time delay. The elements can be manually adjusted, or mounted on motorized stages and automatically controlled. Optical amplifiers can be included to compensate for losses in the time delay elements. | 02-06-2014 |
20160100495 | PACKAGING FOR HIGH-POWER MICROWAVE MODULE - A microwave module is described. The microwave module includes a base bracket, a window plate and a lid. The base bracket is configured to contain a photoconductive switch, a radio-frequency transformer and dielectric oil. The window plate, which is transparent to optical light, covers a first portion of the base bracket in which the photoconductive switch is located. The window plate is sealed to the base bracket. The lid, which includes a cutout to allow the radio-frequency transformer to pass through the lid, covers a second portion of the base bracket in which the radio-frequency transformer is located. The window plate is sealed to the base bracket, and the lid is sealed to the window plate, the base bracket and the radio-frequency transformer to contain the dielectric oil within the microwave module. | 04-07-2016 |
20160126628 | High-Power Microwave Beam Steerable Array and Related Methods - A steerable high-power microwave beam array includes an optical sub-system comprising a laser and an optical time delay unit and a parallel set of RF time delay units. The optical system and/or the RF delay subsystem are utilized to precisely delay the pulses from the microwave antenna elements to provide steerable beam forming. | 05-05-2016 |
Patent application number | Description | Published |
20120118397 | Rapid Deployment Frac Water Transfer System - Methods, systems, and computer program products are provided for rapid deployment and retrieval of a frac water transfer system. | 05-17-2012 |
20130168484 | RAPID DEPL0YMENT FRAC WATER TRANSFER SYSTEM - A method of and apparatus for the rapid deployment of a fracturing water transferring system, along with the rapid picking up and storage of such system after use. In different embodiments the method in includes the use of a tensioning system to retrieve one or more segments of lay flat hose. | 07-04-2013 |
20130313353 | RAPID DEPLOYMENT FRAC WATER TRANSFER SYSTEM - A method of and apparatus for the rapid deployment of a fracturing water transferring system, along with the rapid picking up and storage of such system after use. In different embodiments the method in includes the use of a tensioning system to retrieve one or more segments of lay flat hose. | 11-28-2013 |
20150344263 | RAPID DEPLOYMENT FRAC WATER TRANSFER SYSTEM - A method of and apparatus for the rapid deployment of a fracturing water transferring system, along with the rapid picking up and storage of such system after use. In different embodiments the method in includes the use of a tensioning system to retrieve one or more segments of lay flat hose. | 12-03-2015 |
Patent application number | Description | Published |
20080296251 | Non-Removable Finish and Closure System - Non-removable finish and closure finish system that resists rotational movement so as to be rendered substantially non-removable by the consumer. The closure and finish have complementary thread segments with ratchet-type engaging portions or lugs extending below thread segments on the finish and closure, the closure lugs being disposed on an inner skirt spaced radially inwardly from an outer skirt to inhibit access to the interlocking lugs. | 12-04-2008 |
20090107999 | NON-REAPPLYING DISPENSING CLOSURE - A container assembly includes a container having an unthreaded finish portion and a closure having a downwardly depending sidewall and blocking structure provided at a lower end of the sidewall for securing the closure on to the unthreaded finish portion. The sidewall is provided with a predetermined area of weakness so that in the event that an attempt is made to remove the closure from the container the predetermined area of weakness will rupture, leaving the closure with insufficient structural integrity to be successfully reapplied to the container. The container assembly has particular utility for use in packaging brand-name comestibles such as ketchup for restaurant use. It will frustrate efforts by the restaurant to replenish the brand-name comestible with a cheaper replacement within a dispensing container that is still labeled with the brand of the original product. | 04-30-2009 |
20090236302 | Finish Portion For Plastic Preform and Container and Method of Making - A preform for making a plastic container includes a main body portion and a threaded finish portion that has an outer surface and an inner surface. The threaded finish portion has a proximal and that is unitary with the main body portion of the preform and a distal end that is opposite from the proximal end. At least one external thread is defined on the outer surface of the finish portion. A gripping indentation is advantageously defined in the outer surface and is longitudinally positioned between the external thread and the distal end of the finish portion. A container having such a finish portion and a method of making a container is also disclosed. | 09-24-2009 |
20110155688 | NON-REMOVABLE FINISH AND CLOSURE SYSTEM - Non-removable finish and closure finish system that resists rotational movement so as to be rendered substantially non-removable by the consumer. The closure and finish have complementary thread segments with ratchet-type engaging portions or lugs extending below thread segments on the finish and closure, the closure lugs being disposed on an inner skirt spaced radially inwardly from an outer skirt to inhibit access to the interlocking lugs. | 06-30-2011 |
20110278313 | THREADED FINISH FOR NONREMOVABLE CLOSURES - A finish portion for a plastic container includes a threaded portion having at least one helical thread and a substantially flat thread positioned beneath the helical thread. The helical thread is merged into the flat thread. A transfer bead is positioned beneath the threaded portion and a gripping indentation is defined between the threaded portion and the transfer bead for facilitating automated conveyance. The gripping indentation may be shaped so that no separate ledge is defined between the threaded portion and the transfer bead. The gripping indentation may have a height that is at least about 0.085 inch. The finish portion has a maximum thread diameter and a maximum height, and a ratio of the maximum thread diameter to the maximum height may be at least about 2.3. | 11-17-2011 |
Patent application number | Description | Published |
20090257057 | COMMON-PATH INTERFEROMETER RENDERING AMPLITUDE AND PHASE OF SCATTERED LIGHT - A beam of coherent laser light with linear polarization oriented at 45 degrees to vertical is expanded, and passes through a quarter-wave plate with the fast axis oriented vertically, creating circularly polarized light. The light then passes through a non-polarizing 50/50 beamsplitter. A partial reflector then collinearly reflects a portion of the beam, which is used as the reference beam. The transmitted light passes through a linear polarizer oriented at 45 degrees to vertical, and is focused via a lens onto the sample of interest. Light scattered from this region is re-collimated by the lens and the directed through the linear 45 degree polarizer and through the partial reflector, where it recombines with the reference beam. One use of the invention is to detect microparticles in water. | 10-15-2009 |
20090323061 | Multi-color hetereodyne interferometric apparatus and method for sizing nanoparticles - A nanoparticle sensor is capable of detecting and recognizing single nanoparticles in an aqueous environment. Such sensor may find applications in broad areas of science and technology, from the analysis of diesel engine emissions to the detection of biological warfare agents. Particle detection is based on interferometric detection of multi-color light, scattered by the particle. On the fundamental level, the detected signal has a weaker dependence on particle size (ÿ R | 12-31-2009 |
20120040127 | STACKED OPTICAL ANTENNA STRUCTURES, METHODS AND APPLICATIONS - A stacked optical antenna structure includes a stacked structure including: (1) a first antenna arm located over a substrate; (2) an interstitial gap layer located over at least a portion of the first antenna arm; and (3) a second antenna arm located over at least a portion of the interstitial gap layer located over the first antenna arm, and typically incompletely overlapping the first antenna arm. Thus, a gap width of the stacked optical antenna structure is determined by a thickness of the interstitial gap layer rather than a separation distance of antenna arms that may be formed using a photolithographic method. Embodiments also contemplate a method for fabricating the stacked optical antenna that uses the interstitial gap layer as an etch stop layer. The interstitial gap layer may provide any of several functions within the stacked optical antenna structure. | 02-16-2012 |
20130333077 | Integrated Microscope and Related Methods and Devices - An embodiment includes an integrated microscope including scanning probe microscopy (SPM) hardware integrated with optical microscopy hardware, and other embodiments include related methods and devices. | 12-12-2013 |
20150191003 | METALLIC NANO-TIP APPARATUS, METHODS, AND APPLICATIONS - Methods for template-stripping a single metallic nano-tip structure from a template containing a plurality of ready-to-be-template-stripped inverted metallic nano-tip structures include attaching the metallic nano-tip structure to a wire handle or a cantilever. A metallic nano-tip assembly includes a single metallic nano-tip structure attached to a handle or mounted on a cantilever structure. The metallic nano-tip assembly may be conductive. | 07-09-2015 |
Patent application number | Description | Published |
20120198336 | Grid-Like Guided User Interface for Video Selection and Display - A UI including a “Guide,” presenting a list of videos, having data fields relating to each entry, possibly including multiple data values for a single data field. When focusing on a single entry, the focused-upon entry is expanded and emphasized. The focused-upon entry is highlighted and centered, while other entries have lesser highlighting and centering. When a data field is selected, the focused-upon data field is emphasized (by highlighting, repositioning, or resizing), while other entries have lesser emphasis. Display changes might appear after a brief delay, or in response to further user command. When entries are sorted on selected data fields, entries with multiple data values for those fields are replicated, and the sorting letter is highlighted. The user can move individually down the list of entries, or skip to the next section with a different data value for a selected field. | 08-02-2012 |
20140379521 | ACTIVITY-BASED PERSONAL PROFILE INFERENCE - The aggregation of facts from various sources about an individual may produce an individual profile that may inform personalized services. However, a compilation of facts may be supplemented by monitoring activities of the individual and formulating inferences regarding the individual's individual details, and the confidence of such inferences. Accordingly, a device may compare the detected activities with a behavioral rule set indicating correlations between activities and inferred individual details (e.g., frequently spent weekday evenings and morning departures from a residence imply that the residence is the individual's home; frequent bicycling to work, chosen over other available modes of transportation, implies that the individual is a bicycling enthusiast) to add inferred individual details to the individual profile. Continued monitoring may enable updating based on changes to the individual details. Multiple profiles may be synchronized while respecting the individual's privacy, obtaining the individual's consent to share information, and automatically resolving information conflicts. | 12-25-2014 |
20160092695 | SERVICE PERSONALIZATION WITH FAMILIARITY SENSITIVITY - Personalized services often utilize individual profiles, such as social network profiles, product purchase histories, or browsing histories. However, personalization may exhibit or imply a familiarity level between the service and the individual that is beyond the individual's comfort level. Presented herein are techniques for adapting personalized services to request supplemental individual information only within a current familiarity stage that has been established by the individual with the service, and only to provide a requested usage of a service. Such solicitation may inform the individual of the intended usage of the requested information. Usages that may involve more sensitive information may be predicated upon requesting and receiving individual consent from the individual to advance to a higher familiarity stage. The user may be permitted to provide individual consent to advancing to a higher familiarity stage only for a particular service, and/or only temporarily for a particular usage of the service. | 03-31-2016 |
20160092773 | INFERENCE-BASED INDIVIDUAL PROFILE - In many computing scenarios, individual profiles are generated from facts specified by, observed about, and/or inferred about individuals, and may be used to personalize services to such individual. Such facts may include details provoking a sensitivity of an individual, and it may be undesirable to reveal the collection and use of such facts to the individual; however, such facts may also enable accurately personalized service. These considerations may be balanced by partitioning the individual profile into a foreground profile, comprising facts that are revealed to the individual, and a background profile, comprising facts that are collected about but not revealed to the individual. Services may be covertly personalized for the individual based on the sensitive information stored in the background profile (e.g., restaurant recommendations that are overtly recommended based on the current location of the individual, and also covertly selected based on an inferred income level of the individual). | 03-31-2016 |
Patent application number | Description | Published |
20080274557 | Permethylation Of Oligosaccharides - A solid-phase permethylation procedure is described. For example, solid-phase permethylation can be utilized to prepare permethylated linear and branched, neutral and sialylated oligosaccharides, which can be analyzed by MALDI-MS. | 11-06-2008 |
20080318332 | DISEASE DIAGNOSIS BY PROFILING SERUM GLYCANS - Specific glycomic profiles derived from human blood sera of breast cancer patients and prostate cancer patients were compared to those of disease-free females and males, respectively. The profiles were acquired using MALDI-MS of permethylated N-glycans released from 10-μl sample aliquots. Quantitative permethylation was attained using solid-phase permethylation. Principal component analysis of the glycomic profiles revealed significant differences among the two sets (diseased vs. non-diseased), allowing their distinct clustering. Several sialylated and fucosylated N-glycan structures were found to be useful as biomarkers for cancer, particularly breast cancer or prostate cancer. | 12-25-2008 |
20110015386 | PERMETHYLATION OF OLIGOSACCHARIDES - A solid-phase permethylation procedure is described. For example, solid-phase permethylation can be utilized to prepare permethylated linear and branched, neutral and sialylated oligosaccharides, which can be analyzed by MALDI-MS. | 01-20-2011 |
20110143386 | METHOD FOR THE ANALYSIS OF O-LINKED OLIOSACHARIDES - A method of analyzing O-linked oligosaccharides in a sample is disclosed. The method comprises the steps of digesting a glycoprotein with a proteolytic enzyme, performing solid-phase permethylation of the oligosaccharide, then analyzing the permethylated and non-reduced O-linked oligosaccharides using MALDI-TOF mass spectrometry. | 06-16-2011 |
20150027953 | APPLICATION OF MACROPOROUS SILICA SYNTHESIZED BY A SALT-TEMPLATED AEROSOL METHOD FOR CHROMATOGRAPHY - The present invention discloses a silica particle having a diameter less than or equal to 2 μη, wherein the particle is spherical and comprises interconnected pores having a diameter in the range from 50 nm to 300 nm. The silica particle is preferably produced by spray pyrolysis (=spray drying) of a silica colloid. In the production process, porosity is introduced by means of an inorganic salt, such as NaCl, KCI, LiCl, NaNO3 or Ll NO3, which serves as a pore template. The silica particle may further be functionalized with proteins, peptides, nucleic acids, polysaccharides and proteoglycans, preferably concanavalin A or avidin. The present invention further discloses the use of the silica particle in chromatography, in particular in affinity chromatography. | 01-29-2015 |
Patent application number | Description | Published |
20090056813 | BEVERAGE DISPENSING SYSTEM WITH A HEAD CAPABLE OF DISPENSING PLURAL DIFFERENT BEVERAGES - A beverage dispensing system includes a base to which a dispensing head is removably attached without additional fasteners. Beverage-forming liquids are supplied through a plurality of separate conduits in the base. Each base conduit has a normally closed valve that normally blocks fluid flow. The dispensing head has at least one passageway that receives liquid from an associated one of the base conduits. A projection associated with each dispensing head passageway opens the associated conduit valve to allow fluid flow from the base to the head. Dispensing valves in the dispensing head regulate the dispensing of the beverage. By selectively opening the dispensing valves, a plurality of beverages are formed from combinations of one or more liquids. A dispensing head includes an inlet opening and an outlet opening at each end of a passage extending through a body, the inlet opening having a smaller cross-sectional area than the outlet opening. | 03-05-2009 |
20090057336 | BEVERAGE DISPENSING SYSTEM WITH A HEAD CAPABLE OF DISPENSING PLURAL DIFFERENT BEVERAGES - A beverage dispensing system includes a base to which a dispensing head is removably attached without additional fasteners. Beverage-forming liquids are supplied through a plurality of separate conduits in the base. Each base conduit has a normally closed valve that normally blocks fluid flow. The dispensing head has at least one passageway that receives liquid from an associated one of the base conduits. A projection associated with each dispensing head passageway opens the associated conduit valve to allow fluid flow from the base to the head. Dispensing valves in the dispensing head regulate the dispensing of the beverage. By selectively opening the dispensing valves, a plurality of beverages are formed from combinations of one or more liquids. A dispensing head includes an inlet opening and an outlet opening at each end of a passage extending through a body, the inlet opening having a smaller cross-sectional area than the outlet opening. | 03-05-2009 |
20090057342 | BEVERAGE DISPENSING SYSTEM WITH A HEAD CAPABLE OF DISPENSING PLURAL DIFFERENT BEVERAGES - A beverage dispensing system includes a base to which a dispensing head is removably attached without additional fasteners. Beverage-forming liquids are supplied through a plurality of separate conduits in the base. Each base conduit has a normally closed valve that normally blocks fluid flow. The dispensing head has at least one passageway that receives liquid from an associated one of the base conduits. A projection associated with each dispensing head passageway opens the associated conduit valve to allow fluid flow from the base to the head. Dispensing valves in the dispensing head regulate the dispensing of the beverage. By selectively opening the dispensing valves, a plurality of beverages are formed from combinations of one or more liquids. A dispensing head includes an inlet opening and an outlet opening at each end of a passage extending through a body, the inlet opening having a smaller cross-sectional area than the outlet opening. | 03-05-2009 |
20090057343 | BEVERAGE DISPENSING SYSTEM WITH A HEAD CAPABLE OF DISPENSING PLURAL DIFFERENT BEVERAGES - A beverage dispensing system includes a base to which a dispensing head is removably attached without additional fasteners. Beverage-forming liquids are supplied through a plurality of separate conduits in the base. Each base conduit has a normally closed valve that normally blocks fluid flow. The dispensing head has at least one passageway that receives liquid from an associated one of the base conduits. A projection associated with each dispensing head passageway opens the associated conduit valve to allow fluid flow from the base to the head. Dispensing valves in the dispensing head regulate the dispensing of the beverage. By selectively opening the dispensing valves, a plurality of beverages are formed from combinations of one or more liquids. A dispensing head includes an inlet opening and an outlet opening at each end of a passage extending through a body, the inlet opening having a smaller cross-sectional area than the outlet opening. | 03-05-2009 |
20120118394 | BEVERAGE DISPENSING SYSTEM WITH A HEAD CAPABLE OF DISPENSING PLURAL DIFFERENT BEVERAGES - A beverage dispensing system includes a base to which a dispensing head is removably attached without additional fasteners. Beverage-forming liquids are supplied through a plurality of separate conduits in the base. Each base conduit has a normally closed valve that normally blocks fluid flow. The dispensing head has at least one passageway that receives liquid from an associated one of the base conduits. A projection associated with each dispensing head passageway opens the associated conduit valve to allow fluid flow from the base to the head. Dispensing valves in the dispensing head regulate the dispensing of the beverage. By selectively opening the dispensing valves, a plurality of beverages are formed from combinations of one or more liquids. A dispensing head includes an inlet opening and an outlet opening at each end of a passage extending through a body, the inlet opening having a smaller cross-sectional area than the outlet opening. | 05-17-2012 |
20120118912 | BEVERAGE DISPENSING SYSTEM WITH A HEAD CAPABLE OF DISPENSING PLURAL DIFFERENT BEVERAGES - A beverage dispensing system includes a base to which a dispensing head is removably attached without additional fasteners. Beverage-forming liquids are supplied through a plurality of separate conduits in the base. Each base conduit has a normally closed valve that normally blocks fluid flow. The dispensing head has at least one passageway that receives liquid from an associated one of the base conduits. A projection associated with each dispensing head passageway opens the associated conduit valve to allow fluid flow from the base to the head. Dispensing valves in the dispensing head regulate the dispensing of the beverage. By selectively opening the dispensing valves, a plurality of beverages are formed from combinations of one or more liquids. A dispensing head includes an inlet opening and an outlet opening at each end of a passage extending through a body, the inlet opening having a smaller cross-sectional area than the outlet opening. | 05-17-2012 |
20130008920 | Beverage Dispensing System with a Head Capable of Dispensing Plural Different Beverages - A beverage dispensing system includes a base to which a dispensing head is removably attached without additional fasteners. Beverage-forming liquids are supplied through a plurality of separate conduits in the base. Each base conduit has a normally closed valve that normally blocks fluid flow. The dispensing head has at least one passageway that receives liquid from an associated one of the base conduits. A projection associated with each dispensing head passageway opens the associated conduit valve to allow fluid flow from the base to the head. Dispensing valves in the dispensing head regulate the dispensing of the beverage. By selectively opening the dispensing valves, a plurality of beverages are formed from combinations of one or more liquids. A dispensing head includes an inlet opening and an outlet opening at each end of a passage extending through a body, the inlet opening having a smaller cross-sectional area than the outlet opening. | 01-10-2013 |
20130126555 | Beverage Dispensing System with a Head Capable of Dispensing Plural Different Beverages - A beverage dispensing system includes a base to which a dispensing head is removably attached without additional fasteners. Beverage-forming liquids are supplied through a plurality of separate conduits in the base. Each base conduit has a normally closed valve that normally blocks fluid flow. The dispensing head has at least one passageway that receives liquid from an associated one of the base conduits. A projection associated with each dispensing head passageway opens the associated conduit valve to allow fluid flow from the base to the head. Dispensing valves in the dispensing head regulate the dispensing of the beverage. By selectively opening the dispensing valves, a plurality of beverages are formed from combinations of one or more liquids. A dispensing head includes an inlet opening and an outlet opening at each end of a passage extending through a body, the inlet opening having a smaller cross-sectional area than the outlet opening. | 05-23-2013 |
20140076929 | Beverage Dispensing System with a Head Capable of Dispensing Plural Different Beverages - A beverage dispensing system includes a base to which a dispensing head is removably attached without additional fasteners. Beverage-forming liquids are supplied through a plurality of separate conduits in the base. Each base conduit has a normally closed valve that normally blocks fluid flow. The dispensing head has at least one passageway that receives liquid from an associated one of the base conduits. A projection associated with each dispensing head passageway opens the associated conduit valve to allow fluid flow from the base to the head. Dispensing valves in the dispensing head regulate the dispensing of the beverage. By selectively opening the dispensing valves, a plurality of beverages are formed from combinations of one or more liquids. A dispensing head includes an inlet opening and an outlet opening at each end of a passage extending through a body, the inlet opening having a smaller cross-sectional area than the outlet opening. | 03-20-2014 |
Patent application number | Description | Published |
20090266451 | Ultra-High Strength Martensitic Alloy - An age hardenable martensitic steel alloy is disclosed. The alloy has the following composition in weight percent. | 10-29-2009 |
20100018613 | High Strength, High Toughness Steel Alloy - A high strength, high toughness steel alloy is disclosed. The alloy has the following broad weight percent composition. | 01-28-2010 |
20110165011 | HIGH STRENGTH, HIGH TOUGHNESS STEEL ALLOY - A high strength, high toughness steel alloy is disclosed. The alloy has the following weight percent composition. | 07-07-2011 |
20130037176 | High Strength, High Toughness Steel Alloy - A high strength, high toughness steel alloy is disclosed. The alloy has the following weight percent composition. | 02-14-2013 |
20130146182 | High Strength, High Toughness Steel Alloy - A high strength, high toughness steel alloy is disclosed. The alloy has the following broad weight percent composition. | 06-13-2013 |
20130284319 | High Strength, High Toughness Steel Alloy - A high strength, high toughness steel alloy is disclosed. The alloy has the following weight percent composition. | 10-31-2013 |
20150176109 | High Strength Steel Alloy and Strip and Sheet Product Made Therefrom - An alloy is disclosed that provides a unique combination of very high strength, toughness, and ductility. The alloy can be characterized by the following weight percent composition. | 06-25-2015 |
20160002757 | High Strength, High Toughness Steel Alloy - A high strength, high toughness steel alloy is disclosed. The alloy has the following weight percent composition. | 01-07-2016 |
Patent application number | Description | Published |
20130274000 | MODIFYING USE OF RESOURCES WITHIN A CLOUD-BASED GAMING PLATFORM - A computing platform, system, and method for modifying computing resources that provide and/or support an online game is described. In some implementations, the computing platform determines that one or more cost metrics associated with a currently running online game do not fall with acceptable ranges, and modify and/or adjust the use of computing resources providing the online game. | 10-17-2013 |
20130274020 | COMPUTING PLATFORM FOR SUPPORTING MASSIVELY MULTI-PLAYER ONLINE GAMES - A computing platform, system, and method for providing a massively multi-player online game (MMO, MMOG) is described. In some implementations, the platform provides an abstraction layer between client devices associated with players of a game and computing resources, such as cloud-based resources, that support and provide the game to the players. | 10-17-2013 |
20130274021 | COMPUTING PLATFORM FOR SUPPORTING MASSIVELY MULTI-PLAYER ONLINE GAMES - A computing platform, system, and method for providing a massively multi-player online game (MMO, MMOG) is described. In some implementations, the platform provides an abstraction layer between client devices associated with players of a game and computing resources, such as cloud-based resources, that support and provide the game to the players. | 10-17-2013 |
Patent application number | Description | Published |
20120190131 | Biosensor Electronics - The electrostatic resonators of bridge, cantilever and comb type or piezoelectric resonators with detection electronics are key components of chemical, biological, biochemical and biomedical sensors with sensitivity down to the single molecule detection of ligands. The detection electronics relies on measurement of frequency changes of resonators using phase or signal comparator. The large arrays of these sensors with individual or common sensing circuitry improve detection sensitivity, selectivity and lower incidence of false positives and negatives. | 07-26-2012 |
20120304776 | Chemical and Biomedical NanoSensors - The electrostatic sensors of bridge or cantilever type with multiple electrodes, the electrostatic sensors of comb type and piezoelectric sensors are used for the single molecule detection of ligands. The electrical driving of sensors is separated in some cases from the sensing for increased sensitivity. The large arrays of sensors with individual or common sensing circuits are employed to further improve detection sensitivity. The fabrication of the sensors, their functionalization for detection of many chemical and biological species and electrical circuitry, packaging, microfluidic subsystem and the system architecture are also disclosed. The individual, specific sensing of single species or simultaneous detection of multiple species is realized. The freeze drying or critical point drying after exposure of sensors to ligands present in liquids and detection in reduced pressure or vacuum is employed for increased sensitivity, down to the single molecule. | 12-06-2012 |
20140239179 | Sealed Infrared Imagers - The architecture, design and fabrication of array of suspended micro-elements with individual seals are described. Read out integrated circuit is integrated monolithically with the suspended elements for low parasitics and high signal to noise ratio detection of changes of their electrical resistance. Array of individually sealed, suspended micro-elements is combined with signal processing chip that contains nonvolatile memory with sensitivity calibration of all elements and interpolation between non-functional elements. When the micro-elements are infrared light absorbers, image analysis and recognition is embedded in the processing chip to form the infrared imaging solution for infrared cameras. | 08-28-2014 |
20150362427 | Optical Sensing Array Architectures for Spatial Profiling - Multiple optical architectures based on photosensitive arrays are disclosed. The optical engines collect five dimensional data from the samples with three dimensional spatial information and temporal and spectral information simultaneously, in parallel from all channels, without optical scanning. The photosensitive arrays and/or last component of illumination system are in contact or close proximity of the sample surface. The application of optical engines to sensitive detection of species of interest in the complex reflecting and scattering matrix with the high concentration of interfering species is described. The optical engines are applicable to noninvasive, mobile monitoring of various species of interest in vivo and in vitro. | 12-17-2015 |