Margaret Ann
Margaret Ann Fulenwider, Charlestown, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080248718 | Portable Liquid Dispensing Brassiere - A brassiere based invention of two bladders for collecting, storing, transporting and dispensing liquid. Each bladder has a sealable mouth for filling and a slitted nipple for dispensing. The mouth is an extension of the bladder, sealed when folded over for security and comfort. Each nipple is composed of a semi-flexible material with a small slit which opens when pressure and/or suction is applied and allows the liquid to flow. The bladders are inserted into the pockets of the brassiere and each nipple is secured to the brassiere. The bladders are filled with liquid through the mouth and the bladders may be removed for filling/cleaning. Once each mouth is sealed, unless a nipple is engaged the liquid remains stored within the bladders and may be transported within the brassiere. Optional fabric flaps may be attached to the exterior of the brassiere to lay over each nipple. | 10-09-2008 |
Margaret Ann Marshall, Beverly Hills, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20160060343 | CANCER TREATMENT - The present invention relates to methods of treating cancer, such as melanoma, by administering a CTLA4 antagonist to a subject with a serum C-Reactive Protein (CRP) concentration that is less than or equal to some amount. The invention further relates to methods of treating cancer by determining the level of serum CRP concentration in a subject, and then administering a CTLA4 antagonist if the CRP concentration is less than or equal to a certain amount. The invention further relates to, among other things, the use of serum CRP concentration as a predictive factor for a subject's response to a cancer treatment. | 03-03-2016 |
Margaret Ann Smith, Bristol GB
| Patent application number | Description | Published |
|---|---|---|
| 20110183317 | DETERMINING THE SENSITIVITY OF A CELL TO A DRUG - The present invention provides an in vitro method for determining the resistance or sensitivity of a cell line or patient sample to a deoxyribonucleoside kinase-dependent drug, wherein the method comprises the steps of: (i) treating a patient sample or cell line, or a portion thereof, with a deoxyribonucleoside kinase-dependent drug; (ii) lysing the cells of the patient sample or cell line from step (i); (iii) optionally, mixing a portion of the cell lysate from step (ii) with a bioluminescent reporter bacteria incorporating a gene coding for deoxyribonucleoside kinase; (iv) mixing a portion of the cell lysate from (ii) with a bioluminescent reporter bacteria incorporating a gene coding for a deoxyribonucleoside kinase and a deoxyribonucleoside kinase transcription promoter; (v) mixing a portion of the cell lysate from step (ii) with a bioluminescent reporter bacteria incorporating a gene coding for a deoxyribonucleoside kinase, a deoxyribonucleoside kinase transcription promoter and a dephosphorylating agent; and (vi) measuring the bioluminescence of each of the mixtures from steps (iii) to (v), wherein the comparative levels of bioluminescence of each of the mixtures provides a measure of the resistance or sensitivity to the drug. | 07-28-2011 |
Margaret Ann Wiza, New Berlin, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20130099590 | SYSTEM AND METHOD FOR POWER SUPPLY CONTROL - A resonant power supply is provided. The resonant power supply comprises a series resonant converter configured to convert an input DC voltage to an output DC voltage to generate an output DC voltage. The series resonant converter includes a switching stage, a resonant inductor, a resonant capacitor, and an isolation transformer. The resonant power supply further comprises a converter controller configured to obtain an actual trajectory radius signal based on a resonant inductor current, a resonant capacitor voltage, and a voltage in association with the isolation transformer. The converter controller is further configured to generate a trajectory radius command signal based on a DC voltage command signal and a DC voltage feedback signal, and to generate control signals to be applied to the switching stage based on the actual trajectory radius signal and the trajectory radius command signal. | 04-25-2013 |
| 20130099787 | SYSTEM AND METHOD FOR SERIES RESONANT CONVERTER PROTECTION - A resonant power supply is disclosed. The resonant power supply includes a series resonant configured to convert an input DC voltage to an output DC voltage. The resonant power supply further comprises a converter controller coupled to the series resonant converter and configured to receive a DC voltage feedback signal measured at the output of the series resonant converter, or a resonant current feedback signal representing a resonant current flowing through the series resonant converter. The converter controller is further configured to generate control signals to be applied to the series resonant converter to limit the output DC voltage of the series resonant converter according to the DC voltage feedback signal and a predetermined voltage threshold signal, or to limit the resonant current of the series resonant converter according to the resonant current feedback signal and a predetermined current threshold signal. | 04-25-2013 |