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06th week of 2014 patent applcation highlights part 42
Patent application numberTitlePublished
20140037496CONTROL OF BIO-DECONTAMINATION CYCLES - This invention relates to improvements in the method of controlling bio-decontamination cycles used for the bio-decontamination of enclosed spaces, such as pharmaceutical clean rooms, isolators and hospital wards. The bio-decontamination cycle comprises a number of phases including at least one gassing phase, during which sterilant vapour is generated and circulated within the enclosed space. The method is characterised by the steps of continuously measuring the modified relative humidity of the air in the enclosed space, the modified relative humidity being the ratio of water and sterilant vapour: capacity of water and sterilant vapour in the air, and using the measured modified relative humidity to control the steps of the process.2014-02-06
20140037497PHOTOCATALYTIC AIR TREATMENT SYSTEM AND METHOD - A photocatalytic air treatment system, including apparatuses and methods, for killing and/or mineralizing bacteria, viruses, mold, fungi, spores, mycotoxins, allergens, and other similar microorganisms or agents, and for oxidizing volatile organic compounds (VOCs). The system comprises one or more reactor beds configured in one or more stages with each reactor bed including a plurality of photocatalyst coated media substantially surrounding a plurality of sheathed ultraviolet light sources that may be arranged in a plurality of configurations. Adjacent ultraviolet light sources are positioned so as to create killing zones of photocatalyst coated media therebetween that are irradiated with ultraviolet light from multiple sources and in which an increased number of hydroxyl radicals are present. The photocatalyst generally comprises titanium dioxide, but may include one or more enhancers. The media is formed from or is coated with a material that induces the photocatalyst to form a nano-particle structure.2014-02-06
20140037498INPUT OR OUTPUT OF AN ELECTRON BEAM STERILISATION DEVICE AND STERILISATION METHOD - An electron beam sterilisation device (2014-02-06
20140037499HEALTHCARE FACILITY DISINFECTING SYSTEM - A system and process for disinfecting rooms such as health care facility rooms with an oxygen/ozone mixture is described, which is effective to combat “superbugs” such as 2014-02-06
20140037500Integrated Centrifugal Blood Pump-Oxygenator, an Extracorporeal Life Support System and a Method of De-Bubbling and Priming an Extracorporeal Life Support System - An integrated centrifugal blood pump-oxygenator (2014-02-06
20140037501METHOD AND APPARATUS FOR DESORPTION OF A BLOOD SAMPLE FROM A MEDICAL TEST SHEET - A method for desorption of a blood sample from a dried blood spot on a medical test sheet, for the purpose of biomedical analysis, comprises the steps of: interposing the test sheet inbetween first and second clamping heads; clamping the first and the second clamping heads onto the interposed test sheet; and flushing a desorption area of the clamped test sheet with a sample elution fluid. The clamping heads are transmitting compressive forces to parts of the test sheet. The compressive forces create an imprinted sealing area of the test sheet, which imprinted sealing area has a closed loop shape surrounding a desorption area of the test sheet. The desorption area is contained in a space enveloped by first and second outer surfaces of the first and second clamping heads, respectively, and sealed by the imprinted sealing area.2014-02-06
20140037502SAMPLE ANALYSIS SYSTEM AND SAMPLE ANALYZER - A sample analysis system includes a first measurement unit, a second measurement unit arranged to a downstream side of the first measurement unit, and an information processing section which obtains a measurement result of a sample. The information processing section determines, based on the measurement result of the sample measured by the first measurement unit, whether or not a retest of the sample by the first measurement unit is necessary. When the retest by the first measurement unit is necessary, the information processing section causes the sample container to be transported to a first sample supply position for the first measurement unit and causes the first measurement unit to perform measurement of the sample.2014-02-06
20140037503AUTOMATIC ANALYZER - The present invention performs cleaning on the inner and outer surfaces of a dispensing nozzle without reducing the processing speed of a device. To achieve the object, a feature of the invention is that a dispensing nozzle rinse tank includes a rinse liquid supply port. More specifically, by suctioning rinse liquid from the rinse liquid supply port provided on the dispensing nozzle rinse tank and discharging the rinse liquid into the rinse tank, the inner and outer surfaces of the dispensing nozzle can be rinsed in a short amount of time. According to the invention, it is only required that a rinse liquid supply port be provided on the dispensing nozzle rinse tank, the structure is simple. Moreover, because the inner and outer surfaces of the dispensing nozzle can be rinsed in a short amount of time by shortening the movement distance of the dispensing nozzle, analyses can be performed without reducing the processing speed of the device.2014-02-06
20140037504Electrically Responsive Device - In some aspects, an electrically responsive device can include a composite structure having spatially modulated structural properties that includes a substrate material having a surface and defining a plane; an electrically responsive material layer formed over at least a portion of the surface of the substrate material; an electrode material over portions of the electrically responsive material; and a stiffening material disposed along the electrode material, where the stiffening material has a thickness that varies and has regions of increased thickness that correspond with the regions of the composite structure along which the electrode material is disposed. The spatially modulated structural properties can include the regions of the composite structure along which the electrode material is disposed having the increased material stiffness, exclusive of the electrode material, relative to regions of the composite structure that do not include the electrode material.2014-02-06
20140037505BIOSENSOR AND MEASURING DEVICE USING SAME - Electrodes (A, B) are provided in at least one of plate-like members corresponding to an inner side direction of supply path from an opening of supply path. Electrode (C) of a biological sample is provided in the inner side direction from electrodes (A, B) Reagent part is provided so as to cover electrodes (A, B) and electrode (C). Inflow restricting hole of a sample liquid is provided in at least one of plate-like members corresponding to the portions on both sides of supply path closer to the opening side than the electrode.2014-02-06
20140037506NITROGEN OXIDE CONCENTRATION MEASUREMENT DEVICE - This nitrogen oxide concentration measurement device measures a nitrogen oxide concentration by shining light on a sensor produced by distributing a metal complex of porphyrin or a derivative thereof over a base material, and detecting the amount of light of a specific wavelength, said device comprising a light source that shines light at a nitrogen oxide concentration measurement sensor, a light detector that detects the amount of light of a specific wavelength out of all the light transmitted or reflected by the nitrogen oxide concentration measurement sensor, and a controller that corrects the detection result at the light detector so as to match the amount of light of a specific wavelength outputted from the light detector during exposure to a zero gas to a corrected value.2014-02-06
20140037507ORGANIC COMPOUND PYROLYSIS FLASHOVER ENERGY-SAVING REGENERATION TREATMENT SYSTEM - An organic compound pyrolysis flashover energy-saving regeneration treatment system for remaking organic waste such as family\industrial garbage, sewer mud, agricultural waste and livestock excreta etc. to become liquid and solid regenerated organic compounds by using a waste pre-treatment unit, an organic waste steaming sterilization unit, an organic waste pyrolysis flashover unit, a green energy generation & steam regeneration unit, a solid-liquid organic compound separation unit, a liquid organic compound regeneration unit and a solid organic compound regeneration unit, which compounds are used as organic fertilizer or feed for livestock farming, the system can effectively achieve the objects of recovering resources, purifying environment, saving energy and reducing carbon and regeneration of organic waste for reuse, it further can increase the efficiency of environmental conservation.2014-02-06
20140037508VEHICULAR AIR CLEANER - The present invention relates to a vehicular air cleaner. It is an object to provide a DOR system which can utilize a purifying function of an ozone purifying element containing an activated carbon for a long period of time.2014-02-06
20140037509SUPPLEMENTAL FUEL TO COMBUSTOR OF DUAL FLUIDIZED BED GASIFIER - A method of gasification by introducing a feed material to be subjected to gasification into a dual fluidized bed gasifier comprising a pyrolyzer fluidly connected with a combustor such that a circulation stream comprising a heat transfer material can be continuously circulated between the pyrolyzer, in which the temperature of the circulation stream is reduced, and the combustor, in which the temperature of the circulation stream is increased, wherein the pyrolyzer is operable to convert at least a portion of the feed material into a gasifier product gas comprising hydrogen and carbon monoxide, and wherein the combustor is operable to increase the temperature of the circulation stream via combustion of char introduced thereto with the circulation stream and at least one supplemental fuel. A system for carrying out the method is also provided.2014-02-06
20140037510System and Process for Producing a H2-Containing Gas and Purified Water - System and process for producing a H2014-02-06
20140037511CATALYTIC CONVERTER - A catalytic converter has a catalyst support that is heated due to supply of electricity, and a pair of electrodes that are disposed so as to contact an outer periphery of the catalyst support as seen in an orthogonal cross-section that is orthogonal to a direction in which exhaust flows. By making a volume resistivity of the electrodes be higher than that of electricity supplying portions of external cables that are connected to the electrodes respectively and are for supplying current to the electrodes, heat generated at the electrodes is provided to the catalyst support, and a generated heat amount of the catalyst support in vicinities of the electrodes is made to be large as compared with a generated heat amount at an inner portion of the catalyst support.2014-02-06
20140037512ALKYLATION PROCESS UNIT WITH RECYLE OF HYDROGEN AND RECOVERY OF HYDROGEN CHLORIDE - We provide alkylation process units, one comprising: 2014-02-06
20140037513PROCESS AND APPARATUS FOR PARA-XYLENE PRODUCTION USING MULTIPLE ADSORPTIVE SEPARATION UNITS AND MULTIPLE ADSORPTIVE BED FEED POINTS - A process for separating para-xylene from aromatic compounds is presented. The process introduces throughout a first step-time interval a first mixed xylene stream into a first feed input on a first adsorptive separation unit comprising multiple bed lines. The process further introduces throughout the first step-time interval a second mixed xylene stream into a second feed input on the first adsorptive separation unit. During a first portion of the first step-time interval, the process introduces material from a feed stream used during the first step-time interval into a bed line not used to deliver a stream into, or withdraw a stream from, the first adsorptive separation unit during the first step time interval. During a second portion of the first step-time interval, the process introduces material from a purification zone into the feed stream used during the first step-time interval.2014-02-06
20140037514METHOD AND APPARATUS FOR FLUID DISPERSION - A microfluidic method and device for focusing and/or forming discontinuous sections of similar or dissimilar size in a fluid is provided. The device can be fabricated simply from readily-available, inexpensive material using simple techniques.2014-02-06
20140037515MICROFLUIDIC CARD CONNECTION DEVICE - A device for interconnecting a card including at least one first fluid channel, emerging from a connection side parallel to a support side, the interconnection device including: a first surface configured to receive the support side of the card; a second surface parallel to the first surface, from which a second fluid channel emerges; and a mechanism to hold the card in place, configured to hold a connection side of the card pressed against the second surface of the device, such that first fluid channel is in fluid connection with the second fluid channel.2014-02-06
20140037516SURFACE PREPARATION - A method of processing a component having a capillary passage, particularly a sample testing device for tests involving capillary flow, comprises passing a treatment fluid through the passage to leave a surface coating on the internal surface of the passage.2014-02-06
20140037517TUBE SORTER, SAMPLE PROCESSING SYSTEM, AND SAMPLE TRANSPORTING METHOD - A tube sorter comprising: a rack stocker configured to have stocked therein a sample rack capable of holding one or more sample tubes; a transporting section configured to transport a sample rack; a tube conveyor configured to perform an unloading operation of unloading a sample tube from a sample rack that was transported by the transporting section and a loading operation of loading the sample tube onto a sample rack supplied from or stocked in the rack stocker; and a rack conveyor configured to convey an empty sample rack or a sample rack to be emptied to the rack stocker, is disclosed.2014-02-06
20140037518METHOD OF RECYCLING SPENT NUCLEAR FUEL - The method concerns processing irradiated (spent) nuclear fuel (SNF), it is primarily aimed at isolating and trapping tritium, and can be used in nuclear power industry for treating SNF.2014-02-06
20140037519METHOD FOR PRODUCING OXIDE/HYDROXIDE - Provided is a method for producing an oxide and/or hydroxide wherein the ratio of oxide and hydroxide has been controlled. The method produces an oxide, a hydroxide, or a mixture thereof, and obtains an oxide and/or a hydroxide wherein the ratio of oxide and hydroxide has been controlled by means of changing a specific condition relating to at least one fluid to be processed introduced between processing surfaces (2014-02-06
20140037520PROCESS FOR TREATING SPENT PICKLE LIQUOR AND/OR FERROUS CHLORIDE - A process for treating spect pickle liquor has the steps of mixing the spent pickle liquor with sulfuric acid, introducing oxygen into the mixture of spent pickle liquor and the sulfuric acid for a period of time, and producing diiron(II) tetrachlorosulfate from the oxygen-introduced mixture of sulfuric acid and spent pickle liquor. The spent pickle liquor and the sulfuric acid are introduced into a column. The oxygen is passed under pressure into the column. The intimate mixture of spent pickle liquor, sulfuric acid and oxygen are maintained under pressure for a period of time.2014-02-06
20140037521Processes for Preparing Highly Pure Lithium Carbonate and Other Highly Pure Lithium Containing Compounds - The invention generally relates to methods of selectively removing lithium from various liquids, methods of producing high purity lithium carbonate, methods of producing high purity lithium hydroxide, and methods of regenerating resin.2014-02-06
20140037522METHOD AND APPARATUS FOR PURGING UNWANTED SUBSTANCES FROM AIR - Apparatus comprising: 2014-02-06
20140037523ZEOLITE CATALYST CONTAINING METAL - A catalyst composition is provided having a zeolite material of a CHA crystal structure and a silica to alumina mole ratio (SAR) of about 10 to about 25 and preferably having a mean crystal size of at least 1.0 microns; and a non-aluminum base metal (M), wherein said zeolite material contains said base metal in a base metal to aluminum ratio (M:Al) of about 0.10 to about 0.24.2014-02-06
20140037524CATALYST FOR PURIFYING EXHAUST GAS - Provided is a catalyst for purifying an exhaust gas, the catalyst excelling in catalytic performance and oxygen storage capacity. The catalyst for purifying an exhaust gas is a catalyst for purifying an exhaust gas which includes a ceria-zirconia composite oxide having a pyrochlore structure and a ceria-zirconia composite oxide having a cubic crystal structure, wherein at least a part of the ceria-zirconia composite oxide is composited with the ceria-zirconia composite oxide.2014-02-06
20140037525FILTER AND PROCESS OF USE TO PRODUCE CARBON NANOTUBES FROM AUTOMOTIVE EXHAUSTS - We disclose a novel filter and process that converts the wastes in automotive exhausts into carbon nanotubes. The filter surface is composed of iron of similar catalyst. The filter is placed along the pathway of exhaust streamlines preferably at an angle of more than 5°. and less than 15°. The filter is heated to temperatures in the range of 200-1000° C. The filter described in this invention can work in its own or supplement existing filtration systems. The end product of this filtration system is a material that is commercially valuable. The synthesized carbon nanotubes are purified using ionic liquid solution that is capable of removing undesirable carbonated material and leaving 95% purified carbon nanotubes. The purified carbon nanotubes have a diameter of 20-50 nm and a length of 1-10 micro meters.2014-02-06
20140037526H2S CONVERSION TO SULFUR USING A REGENERATED IODINE SOLUTION - Systems and methods of removing sulfur from a gas stream comprising hydrogen sulfide (H2014-02-06
20140037527Compositions of Matter, and Methods of Removing Silicon Dioxide - Some embodiments include methods of removing silicon dioxide in which the silicon dioxide is exposed to a mixture that includes activated hydrogen and at least one primary, secondary, tertiary or quaternary ammonium halide. The mixture may also include one or more of thallium, BX2014-02-06
20140037528METHOD FOR PRODUCING POROUS GRANULES FROM INORGANIC MATERIAL AND THE USE THEREOF - Build-up granulation and compaction granulation methods are generally known for producing granules from porous inorganic material. In order to allow a cost-efficient yet also reproducible production of porous granules having a more pronounced hierarchical pore structure, the invention relates to a method comprising the following steps: (a) supplying a feedstock flow to a reaction zone in which the feedstock is converted to material particles by means of pyrolysis or hydrolysis, (b) depositing the material particles on a deposition surface (2014-02-06
20140037529METHOD FOR PRODUCING BIS(FLUOROSULFONYL)IMIDE SALT, METHOD FOR PRODUCING FLUOROSULFATE, AND METHOD FOR PRODUCING BIS(FLUOROSULFONYL)IMIDE ONIUM SALT - According to the method for producing bis(fluorosulfonyl)imide salt of the present invention, the method for producing fluorosulfate, and the method for producing bis(fluorosulfonyl)imide onium salt, first, an aqueous solution is prepared by dissolving a mixed liquid containing bis(fluorosulfonyl)imide and fluorosulfonic acid in water. Then, the aqueous solution is neutralized with an alkaline compound, producing bis(fluorosulfonyl)imide salt and fluorosulfate. In the methods, bis(fluorosulfonyl)imide salt, fluorosulfate, and bis(fluorosulfonyl)imide onium salt can be obtained safely and easily.2014-02-06
20140037530METHOD FOR PREPARING VANADIUM-NITROGEN ALLOY - A method for preparing vanadium-nitrogen alloy, the method including: 1) mixing and pressing a vanadium-containing compound, an agglutinant, and a carbon-premixed reducing agent to yield a spherical raw material, and air drying the spherical raw material; and 2) mixing the spherical raw material with a granular carbonaceous reducing agent to yield a mixture, and continually feeding the mixture into a shaft kiln of a medium frequency induction furnace, purging the shaft kiln with pure nitrogen and maintaining a furnace pressure at between 0.01 and 0.03 mPa, drying the mixture at a temperature of between 100 and 600° C., carbonizing and nitriding at a temperature of between 900 and 1350° C., cooling the resulting product to less than 100° C., and discharging the product.2014-02-06
20140037531METHOD FOR PREPARING GRAPHENE - The present invention provides a method for preparing graphene, including reacting graphite in an acid solution in which an oxidant is present so as to obtain a graphene. Compared with the prior art, the advantages of the present invention reside in that, the graphene prepared by the method of the present invention has excellent quality and substantially increased yield and production rate, as compared with mechanical stripping, epitaxial growth, and chemical vapor deposition; and the graphene prepared by the method of the present invention has significantly improved quality, substantially reduced structural defects, and significantly increased conductivity, as compared with oxidation-reduction preparation in the solution-phase; besides, the method is also advantageous for a simple process, mild conditions, low cost, and very easy for scale production. The graphene prepared by the present invention has very broad prospects in the fields of lithium-ion batteries, supercapacitors, functional composite materials, transparent conductive films, and microelectronic devices, etc.2014-02-06
20140037532METHOD FOR FABRICATING CARBON ALLOTROPES - A method of fabricating a carbon allotrope is disclosed. The method includes forming an intermediate carbon template from a carbon feedstock; and creating a pressure and temperature in the carbon template suitable for fabrication of the carbon allotrope from the intermediate carbon template. The pressure and temperature may be created from a shockwave resulting from collapse of a bubble formed during a bubble cavitation process.2014-02-06
20140037533HIGH MODULUS GRAPHITE FIBER AND MANUFACTURING METHOD THEREOF - A high modulus graphite fiber with a tensile modulus of 270˜650 GPa and a plurality of crystal structures with a thickness (Lc) of 20˜70 angstroms is disclosed. Carbon fiber is used as a raw material, and a microwave focusing method is used to perform an ultra quick high temperature graphitization process to increase the temperature of the carbon fiber at a heating speed of 10˜100° C. per minute to a graphitization temperature of 1400˜3000° C., and then to perform a quick graphitization process for 0.5˜10 minutes to form the high modulus graphite fiber.2014-02-06
20140037534The Preparation of Additive Material and its Application in the Cigarette of Tobacco - This invention describes the preparation of additive material and its application in the cigarette of tobacco. This material is titanate nanotube and was synthesized by using a hydrothermal route. Titanate nanotube can be used as additive material in the cigarette of tobacco and the harmful compounds in the mainstream cigarette smoke can be removed significantly.2014-02-06
20140037535Method for Producing Lithium Sulfide for Lithium Ion Cell Solid Electrolyte Material - Provided is a method for producing lithium sulfide based on a new dry method, by which lithium sulfide can be produced more easily at lower cost, and fine pulverization of lithium sulfide can be attempted. Suggested is a method for producing lithium sulfide (Li2014-02-06
20140037536PRODUCTION OF CATALYTICALLY ACTIVE ACTIVATED CARBONS - The invention is directed to a method for preparing catalytically active activated carbon, to catalytically active activate carbon obtainable by the method, and to the use of the catalytically active activated carbon. The method of the invention method comprises the steps of: i) mixing charcoal with one or more organic nitrogen-containing compounds, said nitrogen-containing compounds comprising, next to a first nitrogen atom, at least two or more further heteroatoms selected from the group consisting of nitrogen and oxygen, wherein said further heteroatoms have a lone pair; ii) drying the mixture obtained in step i); iii) activating the dried mixture using steam, thereby producing catalytically active activated carbon.2014-02-06
20140037537COKE TOLERANT STEAM REFORMING CATALYST - Steam reforming a hydrocarbon feed such as liquefied petroleum gas is conducted in the presence of a catalyst comprising a precious metal such as rhodium on a support comprising ceria, zirconia and praseodymium oxide.2014-02-06
20140037538N-ALKYL 2-(DISUBSTITUTED)ALKYNYLADENOSINE-5-URONAMIDES AS A2A AGONISTS - The present invention provides N-alkyl 2-(disubstituted)alkynyladenosine-5′-uronamides and derivatives thereof and pharmaceutical compositions containing the same that are selective agonists of A2014-02-06
20140037539ANTIBODY COCKTAILS FOR BREAST CANCER RADIOIMMUNOTHERAPY - The present invention provides compositions comprising a therapeutically effective combination of radionuclide-labeled anti-EpCAM, radionuclide-labeled anti-EGFR, and radionuclide labeled anti-Tag-72, or their respective antigen binding portions, and a pharmaceutically acceptable carrier, and method of use thereof for the treatment of breast cancer.2014-02-06
20140037540COMPOSITIONS AGAINST CANCER ANTIGEN LIV-1 AND USES THEREOF - Described herein are methods and compositions that can be used for diagnosis and treatment of cancer.2014-02-06
20140037541RADIOIMAGING METHODS USING TEBOROXIME AND THALLIUM - A method for imaging is providing, including administering a teboroxime species to an adult human subject, administering T1-201-thallous chloride to the subject performing a teboroxime species SPECT imaging procedure of the teboroxime species on a region of interest (ROI) of the subject, and, after administering the teboroxime species, performing a T1-201-thallous chloride SPECT imaging procedure of the T1-201-thallous chloride on the ROI. Administering the teboroxime species and the T1-201-thallous chloride and performing the teboroxime species and the T1-201-thallous chloride SPECT imaging procedures comprise administering the teboroxime species and the T1-201-thallous chloride and performing the teboroxime species and the T1-201-thallous chloride SPECT imaging procedures during a time period having a duration of no more than 30 minutes. Other embodiments are also described.2014-02-06
20140037542NOVEL THERANOSTIC PLATFORM FOR TARGETED CANCER THERAPY AND DRUG DELIVERY MONITORING - A compound that includes a quaterrylene dye moiety as core, and a dendrimeric shell. For example, the compound may comprise at least four dendronized polyamides covalently attached to a quaterrylene dye. Also disclosed is a compound, or a pharmaceutically acceptable salt or ester thereof, comprising A(G)2014-02-06
20140037543Anti-Pancreatic Cancer Antibodies - Described herein are compositions and methods of use of anti-pancreatic cancer antibodies or fragments thereof, such as murine, chimeric, humanized or human PAM4 antibodies. The subject antibodies show a number of novel and useful therapeutic characteristics, such as binding with high specificity to pancreatic and other cancers, but not to normal or benign pancreatic tissues and binding to a high percentage of early stage pancreatic cancers. In preferred embodiments, the antibodies bind to pancreatic cancer mucins. The antibodies and fragments are of use for the detection, diagnosis and/or treatment of cancer, such as pancreatic cancer. The antibodies, such as PAM4 antibodies, bind to a PAM4 antigen that shows unique cell and tissue distributions compared with other known antibodies such as CA19.9, DUPAN2, SPAN1, Nd2, B72.3, and Le2014-02-06
20140037544LABELED IODINATED TROPANE FORMULATION - A diagnostic formulation is provided comprising a tropane having a radioactive concentration of at least 1.6 mCi/mL at least about 51 hours post creation. The diagnostic formulation optionally comprises a radiolabeled dopamine transporter (DAT) ligand useful in the diagnosis of Parkinson's disease (PS). One example of a radiolabeled dopamine transporter (DAT) ligand example is [2014-02-06
20140037545INHIBITION OF FIBROSIS AND AF BY TGF-BETA INHIBITION IN THE POSTERIOR LEFT ATRIUM (PLA) - The disclosed methods pertain to diagnosing whether a non-ablative, gene therapy is needed for reducing AF fibrosis in a subject, and if so, methods of reducing AF fibrosis in a subject using gene therapy with a dominant negative TGF-β R2 cDNA expression vector. Kits and computer program products are also described, wherein the kits provide materials for diagnosing and treating AF fibrosis, and the computer program products include a computer readable medium having computer readable program code for monitoring the efficacy of therapeutic ablation of fibrosis in a subject using a gene therapy method.2014-02-06
20140037546MIXTURE OF LIQUID-CRYSTAL COMPOUNDS, SYSTEM OF THREE LIQUID-CRYSTAL MIXTURES AND THEIR USE - Three organic compounds mixtures of liquid-crystal properties, which when mixed together in a precisely determined weight ratio, may show an ability to form thermo-optically active mesophases of established, narrow range thermooptical transitions separation, every 0.5° C., in the temperature range: from 31.8° C. to 32.8° C., from 32.8° C. to 33.8° C., and from 33.8° C. to 34.8° C. and system including these mixtures. The use of these mixtures and the system containing the above mentioned mixtures for colorimetric detection of temperature differentiation on the surface of biological objects in a narrow range of temperatures2014-02-06
20140037547NOVEL PEPTIDIC ACTIVATORS OF TYPE I cGMP DEPENDENT PROTEIN KINASES AND USES THEREOF - The present invention relates to cGMP protein kinase (PKG) and regulatory domains and methods of use thereof. The structural determination of PKG domains is also described. cGMP independent PKG activators and uses thereof are also described.2014-02-06
20140037548Treatment and prevention of diffuse parenchymal lung disease by selective active-site mTOR inhibitors - Provided herein are methods for treating or preventing pulmonary fibrosis in subjects suffering from diffuse parenchymal lung diseases using selective active-site mTOR inhibitors.2014-02-06
20140037549GENETIC MARKERS FOR PROGNOSIS OF RHEUMATOID ARTHRITIS TREATMENT EFFICACY - The present invention discloses markers useful in predicting the responsiveness of a subject having, or at risk of developing rheumatoid arthritis (RA) to treatment with anti-TNF agents. Particularly, the present invention discloses the allelic configuration of the CD6 gene and/or the STXBP6 gene which is indicative of the degree of responsiveness to anti-TNFα treatment of RA.2014-02-06
20140037550COLCHICINE COMPOSITIONS AND METHODS - Stable ultrapure colchicine compositions comprising ultrapure colchicine and a pharmaceutically acceptable excipient are described. The compositions can be tablets. Methods for preparing such compositions and methods of use are also disclosed. Methods of treating gout flares with colchicine compositions are also disclosed.2014-02-06
20140037551ANTIBODIES TO HUMAN B7X FOR TREATMENT OF METASTATIC CANCER - Methods are provided for treating metastatic cancer in patients having metastatic cancer or for preventing metastasis in cancer patients at risk for metastasis comprising administering to the patient an antibody to B7x, or an active antibody fragment that binds B7x, in an amount effective to treat or prevent metastasis.2014-02-06
20140037552PRUSSIAN BLUE BASED NANOPARTICLE AS MULTIMODAL IMAGING CONTRAST MATERIAL - The invention relates to a Prussian Blue based nanoparticle comprising a Prussian Blue based metal core doped with one or more metal isotope and an organic biocompatible coating. The invention relates furthermore to a process for the preparation of said nanoparticle, and the use thereof as imaging contrast material or in the therapy.2014-02-06
20140037553BACTERIUM-BASED MICROROBOT CAPABLE OF TARGETING CANCER TISSUE - To provide a bacterium-based microrobot which can be specifically targeted to cancer in vivo, the present invention provides a drug delivery system for cancer tissue, comprising a bacterium, and a microbead encapsulated with at least one drug, wherein biotin is bound to a surface of the bacterium and a surface of the microbead is coated with streptavidin.2014-02-06
20140037554CUPREDOXIN DERIVED TRANSPORT AGENTS AND METHODS OF USE THEREOF - The present invention discloses methods and materials for delivering a cargo compound into a cancer cell. Delivery of the cargo compound is accomplished by the use of protein transduction domains derived from cupredoxins. The invention further discloses methods for treating cancer and diagnosing cancer.2014-02-06
20140037555Process For Oral Care Material Taste And/Or Odor Improvement - Processes for improving the taste of oral care raw materials using solvent extraction, said process comprising the steps of: providing a solid oral care raw material composition in need of treatment wherein said oral care raw material composition comprises an orally acceptable raw material and one or more undesirable non-polar materials; contacting said oral care raw material composition with an extraction solvent to form an extraction mixture comprising a solid phase and a solvent phase; and separating the solid phase from the extraction mixture; wherein the extraction solvent is selected from solvents having individual Hansen solubility parameters of a dispersion force component (δ2014-02-06
20140037556Novel Use - A oral care composition comprising a triple polymer system and a source of fluoride ions for combating (i.e. helping to prevent, inhibit and/or treat) dental erosion and/or tooth wear is described. Such compositions are also of use in combating dental caries.2014-02-06
20140037557Dental Whitening Method - A two-step system for whitening stained or discolored teeth by applying separately, and sequentially, to the teeth (i) a bleaching activator followed by (ii) a bleaching agent. In preferred embodiments the bleaching activator is a transition metal catalyst and the bleaching agent is a peroxide.2014-02-06
20140037558Dental Whitening Method - A two-step system for whitening stained or discolored teeth by applying separately, and sequentially, to the teeth (i) a bleaching activator followed by (ii) a bleaching agent. In preferred embodiments the bleaching activator is a transition metal catalyst and the bleaching agent is a peroxide.2014-02-06
20140037559PROCESS FOR PRODUCING (3S)-1-MENTHYL 3-HYDROXYBUTYRATE AND SENSATE COMPOSITION - Disclosed is a cooling component or sensate component which does not have undesirable stimulus feeling, bitterness and the like and is excellent in the persistence of refresh-feeling and cool-feeling, a sensate composition which comprises the same, and various products that comprise said sensate composition. Also disclosed is a cooling agent comprising (3S)-1-menthyl 3-hydroxybutyrate represented by the following formula (I)2014-02-06
20140037560NOVEL PEPTIDES INVOLVED IN THE SCF C-KIT SIGNALING PATHWAY AND COMPOSITIONS COMPRISING SAME - This invention relates to peptide compounds of general formula (I) R2014-02-06
20140037561COMPOSITION AND METHODS OF ENHANCED SKIN CELL TURNOVER - A composition is provided that capitalizes on the biological activity of trichloroacetic acid, but effectively reduces or eliminates TCA induced irritation allowing the composition to be used as a wrinkle effacer or stimulant of skin cell turnover; uses previously thought as commercially impossible with TCA. Also provided are processes of effacing wrinkles or stimulating skin cell turnover including applying the inventive composition to the skin of a subject.2014-02-06
20140037562COMPOSITIONS WITH METAL CHELATOR STABILIZED CATIONIC AMMONIUM COMPOUNDS AND A SKIN BENEFIT AGENT - Stabilized cationic ammonium compounds are described. The compounds are stabilized with metal chelators that impede the generation of nitrogen comprising groups from the cationic ammonium compounds.2014-02-06
20140037563COMPOSITIONS COMPRISING PAULOWNIA TOMENTOSA WOOD EXTRACTS AND USES THEREOF - Provided are compositions comprising Paulownin or an extract of 2014-02-06
20140037564NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR - Provided are a novel compound having skin-whitening, anti-oxidizing and PPAR activities and a medical use thereof, and the compound has skin-whitening activities for the suppression of tyrosinase, and accordingly, is useful for use in skin-whitening pharmaceutical composition or cosmetic products; has anti-oxidant activities, and accordingly, is useful for the prevention and treatment of skin-aging; and has PPAR activities, and in particular, PPARα and PPARγ activities, and accordingly, is useful for use in pharmaceutical compositions or health foods which are effective for the prevention and treatment of obesity, metabolic disease, or cardiovascular disease.2014-02-06
20140037565COMPOSITION COMPRISING A POLYOL AND A OIL-SOLUBLE POLAR MODIFIED POLYMER - The invention relates to a composition comprising a oil-soluble polar modified polymer and a hyperbranched polyol.2014-02-06
20140037566Antiperspirant Compositions and Methods - Achieving enhanced scent expression in antiperspirant compositions and methods.2014-02-06
20140037567Antiperspirant Compositions and Methods - Achieving enhanced scent expression in antiperspirant compositions and methods.2014-02-06
20140037568HAIR CARE COMPOSITION COMPRISING PYRITHIONE AND A PEARLISER SYSTEM BASED ON BISMUTH OXYCHLORIDE - Hair care composition comprising a metal pyrithione and a pearliser system characterized by a bismuth oxychloride component.2014-02-06
20140037569ADHESIVE AGENT FOR APPLICATION ON A SANITARY OBJECT - Agent for sanitary facilities that can be applied directly on the sanitary object, adheres, and is flushable only after a large number of flushes. The agent comprises fillers from the group of surfactants and a bonding agent, wherein the bonding agent is selected from the group of polyalkylene derivatives, hydrogentated polystyrol derivatives, copolymers from the group of monoalkyl esters of poly(methyl vinyl ether/carbonic acid anhydrides, olefin homopolymers, and copolymers of two or more olefins, wherein the olefin homopolymers and copolymers can also be partially hydrogenated, partially oxidized, or further functionalized by graft molecules, and from the group of polyalkyleneimines, including in alkoxylized form, polyetheramines (alkoxylized amines) and polyglycerin polyether alkyl carbonic acids, polymers or derivatives comprising said polymer groups. The viscosity of the agent is at least 30 Pa s at 20° C.2014-02-06
20140037570NBPT solution for preparing urease inhibited urea fertilizers prepared from N-alkyl; N, N-alkyl; and N-alkyl-N-alkoxy amino alcohols - Solutions are prepared by dissolving N-(n-butyl)-thiophosphoric triamide (NBPT) in one or more N-alkyl amino alcohols, N,N-dialkyl amino alcohols, N-alkyl-N-alkoxy amino alcohols, and mixtures thereof. The solutions may be used in urea fertilizers to reduce nitrogen volatilization, or to reduce the odor of animal waste. Methods of preparing urea fertilizers and the resultant products are also described.2014-02-06
20140037571MALODOUR COUNTERACTING COMPOSITIONS - A malodour-counteracting composition containing2014-02-06
20140037572POLYMERIZABLE ORGANOBORON ALKYD RESIN ANTI FOULING COATINGS - A compound includes a boron atom attached to at least one C2014-02-06
20140037573CONJUGATES, PARTICLES, COMPOSITIONS, AND RELATED METHODS - Particles and conjugates for delivering nucleic acid agents. Compositions containing the particles, the conjugates, or both. Methods of using the particles, the conjugates, and the compositions.2014-02-06
20140037574PHARMACEUTICAL COMPOSITION - The invention provides a pharmaceutical composition for oral administration of a pharmaceutically active agent to a subject, including the pharmaceutically active agent and an inhibitor of CYP3A4. Administration of the inhibitor and the pharmaceutically active agent reduces pre-systemic degradation of the pharmaceutically active agent by CYP3A4. The inhibitor can be poly(ethylene glycol), methoxy poly(ethylene glycol), aminated poly(ethylene glycol), O-(2-aminoethyl)-O-methoxy poly(ethylene glycol), polyoxyethylene glycol, branched poly(ethylene glycol), 3-arm poly(ethylene glycol), 4-arm poly(ethylene glycol), 8-arm-poly(ethylene glycol)polyamine, poly(L-lysine), poly(L-arginine), poly(L-alanine), poly(L-valine), poly(L-serine), poly(L-histidine), poly(L-isoleucine), poly(L-leucine), poly(L-glutamic acid), poly(L-glutamine), poly(L-guanidine), poly(methyl methacrylate), polyvinyl acetate, polyacrylate, poly(lactic-co-glycolic acid) and derivatives thereof. A method of treatment is also described.2014-02-06
20140037575Wild Game drops - Wild Game Drops is a soy wax drop impregnated with game animal liquid urine or fragrance oil. These drops are 100% biodegradable, non-toxic, environmentally safe and made from 100% dehydrogenated soy oil. The drops are used by a “hunter” as a wild game animal attractant or lure. The Wax is poured into a mold, frozen and released then bagged into individual bags for a no mess application. The drops can be placed anytime during the hunting process to allow the urine or fragrance oil to permeate into the air. The drops do not have to be melted as they will slowly release the scent as the day warms. Animals are attracted to the soy wax drops due to the different types of urine or fragrance oil used.2014-02-06
20140037576P2X7: Inhibition Of Epithelial Cancers and Papillomas - The present invention demonstrates that P2X2014-02-06
20140037577ANTI-PARASITIC METHODS AND COMPOSITIONS UTILIZING DIINDOLYLMETHANE-RELATED INDOLES - The present invention includes methods and compositions for the treatment and prevention of protozoal parasitic infections utilizing Diindolylmethane-related indoles. Additive and synergistic interaction of Diindolylmethane-related indoles with other known anti-parasitic and pro-apoptotic agents is believed to permit more effective therapy and prevention of protozoal parasitic infections. The methods and compositions described provide new treatment of protozoal parasitic diseases of mammals and birds including malaria, leishmaniasis, trypanosomiasis, trichomoniasis, neosporosis and coccidiosis.2014-02-06
20140037578IL-25 Treatment of Obesity and Metabolic Disorders - The present invention provides a method for reducing the weight of a subject, preventing weight gain in a subject, lowering blood glucose, or treating hepatic steatosis, comprising administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical composition comprising interleukin-25 or IL-25-activated macrophages. In addition, the present invention provides a method of treating cachexia or promoting weight gain in a mammal in need of such treatment, comprising administering to the mammal a therapeutically effective amount of a pharmaceutical composition comprising an inhibitor or antagonist of interleukin-25 in a mammal in the treatment of cachexia.2014-02-06
20140037579Inhibition of Dendritic Cell-Driven Regulatory T Cell Activation and Potentiation of Tumor Antigen-Specific T Cell Responses by Interleukin-15 and MAP Kinase Inhibitor - The invention involves the discovery that if dendritic cells loaded with a tumor antigen are cultured in interleukin-15 (IL-15), or if T cells activated by the dendritic cells are cultured in IL-15, Treg activity that is specific for the tumor antigen is reduced. This reduction in Treg activity results in an increase in anti-tumor immune response. Another embodiment of the invention involves the discovery that incubating dendritic cells with a MAP kinase inhibitor in combination with IL-15 gives synergistic benefits when the dendritic cells are used to activate T cells. Dendritic cell and T cell compositions incubated with IL-15 or a MAP kinase inhibitor are provided.2014-02-06
201400375803'-[(2Z)-[1-(3,4-DIMETHYLPHENYL)-1,5-DIHYDRO-3-METHYL-5-OXO-4H-PYRAZOL-4-Y- LIDENE]HYDRAZINO]-2'-HYDROXY-[1,1'-BIPHENYL]-3-CARBOXYLIC ACID bis-(MONOETHANOLAMINE) - An improved thrombopoietin mimetic, the bis-(monoethanolamine) salt of 3′-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2′-hydroxy-[1,1′-biphenyl]-3-carboxylic acid.2014-02-06
20140037581METHODS TO DIAGNOSE AND IMMUNIZE AGAINST THE VIRUS CAUSING HUMAN MERKEL CELL CARCINOMA - The present invention provides isolated or substantially purified polypeptides, nucleic acids, and virus-like particles (VLPs) derived from a Merkel cell carcinoma virus (MCV), which is a newly-discovered virus. The invention further provides monoclonal antibody molecules that bind to MCV polypeptides. The invention further provides diagnostic, prophylactic, and therapeutic methods relating to the identification, prevention, and treatment of MCV-related diseases.2014-02-06
20140037582Feed Additive Composition - A method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for improving dietary phosphorus absorption and retention, or for improving the efficacy of the phytase, or for improving the subject's resistance to necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for reducing populations of pathogenic bacteria in the gastrointestinal tract of a subject, or for reducing nutrient excretion in manure, which method comprising administering to a subject at least one direct fed microbial in combination with a phytase, wherein the phytase is administered to the subject at a dosage of more than about 1500 FTU/kg feed.2014-02-06
20140037583METHODS AND COMPOSITIONS SUITABLE FOR PREVENTING AND TREATING HYPERLEPTINEMIA - The invention provides methods and compositions suitable for preventing and treating hyperleptinemia, preventing and treating insulin resistance, preventing and treating cardiovascular disease, preventing and treating obesity, preventing and treating hyperlipidemia, and preventing and treating hypertension in an animal. The methods comprise administering one or more isoflavones to the animal, preferably in amounts of from about 0.001 to about 10 g/kg/day.2014-02-06
20140037584ONCOLYTIC RHABDOVIRUS - Embodiments of the invention include compositions and methods related to non-VSV rhabdoviruses and their use as anti-cancer therapeutics. Such rhabdoviruses possess tumor cell killing properties in vitro and in vivo.2014-02-06
20140037585AAV8 Vector with Enhanced Functional Activity and Methods of Use Thereof - Improved compositions and methods for AAV mediated gene therapy are disclosed.2014-02-06
20140037586MYCOVIRUS, PLANT-PATHOGENIC FUNGUS, PLANT DISEASE CONTROL AGENT, METHOD FOR CONTROLLING PLANT DISEASE, AND METHOD FOR ATTENUATING PLANT-PATHOGENIC FUNGUS - It is intended to exert a higher control effect on plant-pathogenic fungi. The mycovirus of the present invention has 5 types of double-stranded RNAs, wherein 4 types of double-stranded RNAs out of the 5 types of double-stranded RNAs have 81%, 75%, 72%, and 73% or higher homologies to the nucleotide sequences represented by SEQ ID NOs: 1 to 4, respectively. As an example, a novel mycovirus MoCV3 is used.2014-02-06
20140037587BENEFICIAL EFFECTS OF BACTERIOPHAGE TREATMENTS - The invention relates to use of one or more bacteriophages in vivo in a human or animal in order to induce sensitivity to chemical antibiotics in bacterial cells, where such susceptibility is heritable, independent of continuing bacteriophage metabolism within those cells, and does not relate to the destruction of a biofilm to induce such sensitivity.2014-02-06
20140037588INJECTABLE THERMORESPONSIVE POLYELECTROLYTES - Provided herein are compositions, devices and systems comprising thermoresponsive, biodegradable elastomeric materials, and methods of use and manufacture thereof.2014-02-06
20140037589NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF - This invention provides methods for preparing novel mammalian multipotent stem cells (MSCs), compositions thereof, and methods of preparing and administering the cells.2014-02-06
20140037590Isolation and Characterization of Progenitor Cells From Mesothelium - Populations enriched for smooth muscle progenitors are obtained by selection on the basis of expression of specific cell surface markers.2014-02-06
20140037591Methods for reducing and/or preventing excessive cellular apoptosis - The invention is directed to novel methods for reducing the number of apoptotic cell deaths in a population of cells undergoing excessive cellular apoptosis. The invention is also directed to novel methods for preventing apoptotic cell death in a population of cells at risk for developing excessive cellular apoptosis. In particular, the invention is directed to novel methods for reducing or preventing excessive cellular apoptosis comprising exposing cells exhibiting or at risk for developing excessive cellular apoptosis to a novel cellular factor-containing composition called Amnion-derived Cellular Cytokine Solution (referred to herein as ACCS), which is obtained from the culturing of Amnion-derived Multipotent Progenitor (AMP) cells, or AMP cells.2014-02-06
20140037592METHOD FOR PRODUCING REGENERATIVE ORGAN PRIMORDIUM PROVIDED WITH GUIDE FOR TRANSPLANTATION, COMPOSITION CONTAINING REGENERATIVE ORGAN PRIMORDIUM PROVIDED WITH GUIDE FOR TRANSPLANTATION PRODUCED THEREBY, AND METHOD FOR TRNSPLANTING REGENERATIVE ORGAN PRIMORDIUM PROVIDED WITH GUIDE FOR TRANSPLANTATION - A method for producing a regenerative organ germ for transplantation includes using regenerative organ germ for transplantation ensuring continuity with a recipient after transplantation and facilitating transplantation procedures. A method for producing a regenerative organ germ provided with a guide for transplantation includes preparing a regenerative organ germ by closely contacting a first cell mass, which substantially consists of mesenchymal cells, and a second cell mass, which substantially consists of epithelial cells, culturing these cell masses within a support, and inserting the guide into the regenerative organ germ.2014-02-06
20140037593Tricalcium Phosphate Binding Peptides And Uses Thereof - The invention is directed to a composition comprising all or a portion of a beta-tricalcium phosphate (β-TCP) bound to all or a portion of a β-TCP binding peptide and methods of use thereof.2014-02-06
20140037594COMPOSITIONS AND METHODS FOR TREATING BONE FORMATION DISORDERS - The present invention relates to compositions and methods for the detecting, treating, and empirically investigating disorders associated with bone formation (e.g., osteoporosis). In particular, the present invention provides compositions and methods for using maspin and targets of maspin in the diagnosis, treatment, and empirical investigation of disorders associated with bone formation (e.g., osteoporosis).2014-02-06
20140037595TISSUE GRAFTING METHOD - The tissue grafting method relates to a tissue graft material, a method of preparing the material, and a method of using the material. The tissue graft material is made from the tunica serosa of the small intestine of a warm-blooded vertebrate, which has been delaminated from the tunica muscularis, tunica submucosa, and the tunica mucosa of the intestinal tissue. The tissue graft material may be perforated by discrete punctures. The tissue graft material is dehydrated by air drying or vacuum drying, sterilized with ethylene oxide, and stored in a hermetically sealed enclosure at room temperature until needed, having an indefinite storage life. When needed, the tissue graft material is rehydrated, cut to match the size of the wound, and applied to the wound. The graft may be overlaid with nylon mesh, or bandaged with an elastic tubular dressing.2014-02-06
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