| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 800025000 | Via microinjection of DNA into an embryo, egg cell, or embryonic cell | 9 |
| 20100024050 | PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF - The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems isolated from or derived from non-bacterial organisms, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system. | 01-28-2010 |
| 20100146655 | METHODS AND MATERIALS FOR PRODUCING TRANSGENIC ANIMALS - Transgenic artiodactyls are described as well as methods of making and using such artiodactyls. | 06-10-2010 |
| 20100205685 | Injecting Drosophila Embryos - The present invention provides systems that allow reliable multiplexed transformation of | 08-12-2010 |
| 20110047635 | METHODS AND COMPOSITIONS FOR TRANSPOSON-MEDIATED TRANSGENESIS - Methods and compositions for transposon-mediated transgenesis are provided herein. In some embodiments, methods are provided for generating a transgenic embryo containing a piggyBac-like transposon. In some embodiments, such methods can include: contacting a nucleic acid containing a transgene flanked by two terminal repeats with one of the group consisting of: a piggyBac-like transposase polypeptide and a nucleotide sequence encoding a piggyBac-like transposase to form a mixture; contacting the mixture with a sperm to form a composition; and introducing the composition into an unfertilized oocyte to form a transgenic embryo, wherein the piggyBac-like transposase catalyzes the integration of the transgene into the genome of the embryo. In some embodiments, the piggyBac-like transposase can be encoded by a nucleotide sequence on the same nucleic acid containing the transgene. In some embodiments, the nucleic acid encoding the piggyBac-like transposase can be an mRNA. | 02-24-2011 |
| 20110061120 | SELF-CLEAVING RIBOZYMES AND USES THEREOF - In certain embodiments, the disclosure relates to compositions and methods relating to a ribozyme-based gene regulation system that functions in mammalian cells. In certain specific embodiments, the disclosure relates to schistosome self-cleaving RNA mutant motifs. | 03-10-2011 |
| 20120030783 | RATIONALLY DESIGNED MEGANUCLEASES WITH ALTERED SEQUENCE SPECIFICITY AND DNA-BINDING AFFINITY - Rationally-designed LAGLIDADG meganucleases and methods of making such meganucleases are provided. In addition, methods are provided for using the meganucleases to generate recombinant cells and organisms having a desired DNA sequence inserted into a limited number of loci within the genome, as well as methods of gene therapy, for treatment of pathogenic infections, and for in vitro applications in diagnostics and research. | 02-02-2012 |
| 20150089681 | METHODS OF MODIFYING A TARGET NUCLEIC ACID WITH AN ARGONAUTE - This disclosure provides for compositions and methods for the use of designed nucleic acid-targeting nucleic acids, Argonautes, and complexes thereof. | 03-26-2015 |
| 20150106964 | METHODS FOR PRODUCING ORGANISMS CAPABLE OF INGESTING AND DIGESTING OMEGA-3 RICH SOURCES IN GREATER VOLUME AND OMEGA-3 ENRICHED HYBRID ORGANISMS - The methods of producing an organism capable of ingesting and digesting omega-3 rich sources; for producing an organism that desires the consumption of omega-3 rich sources; and for producing an omega-3 enriched hybrid organism are each described. Each method isolates a donor DNA/RNA strand of a donor organism; extracts the donor DNA/RNA strand from the donor organism; and fuses the donor DNA/RNA strand into a receiving DNA/RNA strand of a receiving organism. In the first method, the donor organism is capable of ingesting and digesting omega-3 rich sources, and the receiving organism is incapable of ingesting or digesting omega-3 rich sources. In the second method, the donor organism desires the consumption of omega-3 rich sources, and the receiving organism does not desire the consumption of omega-3 rich sources. In the third method, the donor organism produces omega-3 fatty acids, and the receiving organism is unable to produce omega-3 fatty acids. | 04-16-2015 |
| 20160050894 | MATERNALLY INDUCED STERILITY IN ANIMALS - The present invention provides Maternal Sterility Constructs (MSC) and methods of producing sterile progeny lacking germ cells. Female fish carrying the MSC transgene will give rise to a sterile generation, as the MSC specifically eliminates Progenitor Germ Cells (PGCs) of her progeny. These females are called lineage ending females. Male fish carrying the MSC transgene, however, give rise to fertile progeny (assuming the male is not derived from an MSC-transgenic female). Thus, MSC transgenic males can be used to propagate the transgenic line. The invention can be advantageously applied to provide effective population control and improve culture performance of farmed species, such as fish. | 02-25-2016 |
