| Entries |
| Document | Title | Date |
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| 20080243212 | SYSTEMS AND METHODS FOR THERMAL NEUROINHIBITION - Disclosed herein, among other things, is system for thermal neuroinhibition. According to an embodiment, the system includes at least one implantable fluid-filled conduit adapted to be placed adjacent to a neural target. The system also includes an implantable housing including a power source, a heat pump deriving power from the source and connected to the conduit, and a controller within the housing. The controller is connected to the heat pump, and is adapted to control the heat pump to effect fluid flow in the conduit to cool the neural target using electromechanical refrigeration to reversibly inhibit neural activity as part of a medical treatment. | 10-02-2008 |
| 20080275535 | Catheter for Topical Cooling and Topical Cooling Device using the same - Topical cooling of spinal cord, brain, esophagus, etc. can be selectively and continuously carried out under convenient control without causing any changes in internal pressure of spinal cord cavity, brain pressure, etc. by inserting a catheter, which has no hole connecting to the outside and in which a heat-cooling medium is circulated in its inner space to thereby cool a topical site; into the spinal cord, the epidural cavity, the subdural cavity or the subarachnoid cavity of the brain or the esophageal cavity and placing therein and then circulating the heat/cooling medium within the inner space of the catheter; or using a device composed of a heat absorption member in the form of a catheter, a heat insulation member and a heat radiation member, inserting the heat absorption member in the form of a catheter into the spinal cord, the epidural cavity, the subdural cavity or the subarachnoid cavity of the brain or the esophageal cavity and placing therein and then absorbing heat from the heat absorption member and radiating the heat from the heat radiation member via the heat insulation member, thereby contributing to the treatment of spinal diseases including prevention of paraplegia accompanying thoracic aortic aneurysm surgery and the treatment of brain injury, esophageal injury and so on. | 11-06-2008 |
| 20080312723 | Apparatus and Method for Inducing Suspended Animation Using Rapid, Whole Body, Profound Hypothermia - Disclosed is a transportable apparatus that maintains a large volume of a cold solution at a preset low temperature and rapidly delivers it to an irresuscitable patient's thoracic aorta at a preset and controlled flow rate, while monitoring pressure and eliminating the introduction of air embolisms into the patient, for the purpose of inducing profound hypothermia and suspended animation until proper treatment of the patient is available. The induction of suspended animation is intended for preservation of viability of the brain, heart, and organs for subsequent repair and resuscitation or for organ harvesting. The procedure may be performed by emergency personnel on the scene of an accident and/or while the patient is being transported in an emergency vehicle, or while in a hospital. | 12-18-2008 |
| 20090069875 | Esophageal cooling system for ablation procedures associated with cardiac arrhythmias - The invention involves a system and method for an esophageal cooling system suitable for use during surgical procedures associated with the left atrium of the heart and most particularly ablation procedures associated with atrial fibrillation. The esophageal cooling system is suitable for use irrespective of whether the ablation procedure is intraoperative or catheter based. The system includes an esophageal catheter constructed and arranged to fit within the patients esophagus. Suitably located along the esophageal catheter is a phoximal balloon for occluding an upper portion of the esophagus. The phoximal balloon includes a coolant lumen for transferring temperature controlled liquid to the area where the esophagus may be in contact with the atrium of the heart. The liquid is expelled through a nozzle which directs the liquid to the inner surface of the esophagus. A suction lumen also extends through the phoximal balloon to evacuate the used coolant from the lower portion of the esophagus or gastrum of the patient. | 03-12-2009 |
| 20090069876 | System and Method for thermally Treating Tissues - A system and method are provided for thermally treating tissues in percutaneous surgery or endoluminal treatments. The system consists of at least one catheter for thermally treating a tissue, hydraulic unit for circulating fluids through the catheters and a control station by which an operator is displayed with, and inputs and/or modifies, working parameters of the system. The catheters have an operational face, which is optionally expandable and encloses a lumen through which the fluids are circulated. The method disclosed implements cooling of the targeted tissue prior to its heating. For heating and or cooling the tissues, the operational face of a catheter is pressed against a surface of the targeted tissue while heat emitted from or conducted to the tissue is respectively transferred into or from the circulated fluids. | 03-12-2009 |
| 20090076573 | Hypothermia Devices and Methods - A method of providing hypothermia to a patient including the steps of inserting a fluid delivery member into a peritoneal cavity of the patient; delivering hypothermia fluid from a fluid source into the peritoneal cavity through the delivery member; and limiting fluid pressure within the peritoneal cavity without providing feedback control to the fluid source. The invention also provides an apparatus for practicing the method. | 03-19-2009 |
| 20090082837 | Hand-held Thermal Ablation Device - A thermal ablation system, comprises a device housing and an elongated probe extending distally from the device housing, the probe including an outflow fluid passage extending between proximal and distal outflow openings and a return fluid passage extending between proximal and distal return openings, the probe being shaped and sized for insertion into a body lumen so that, when the distal outflow and return openings are located at a desired position within the body, the proximal outflow and return openings remain outside the body in combination with a pump disposed in the device housing in fluid communication with the outflow and return fluid passages of the probe for circulating a fluid through the outflow lumen into a target area of the body and back through the return lumen to the device housing and a heating element in the device housing for heating the fluid. Fluid connectors place the pump and the heating element in fluid communication with a supply of fluid and a fluid drain. | 03-26-2009 |
| 20090138063 | APPARATUS AND METHODS FOR COOLING A REGION WITHIN THE BODY - Apparatus and methods for cooling selected regions within a body are described herein. An implantable cooling system is used to cool regions of the brain, spinal cord, fibrous nerve bodies, e.g., vagus nerve, etc. down to about 30° C. to diminish nerve impulses which control seizures or chronic pain. The system includes an implantable unit containing a pumping mechanism and/or various control electronics. It also has a heat exchanger attachable to a tubular body organ, such as the superior vena cava or the inferior vena cava, through which the heat is effectively dissipated. Also included is a heat pump such as a Peltier junction configured to be placed into contact with the region of tissue to be cooled. The heated portion of the Peltier junction is cooled by a liquid heat transfer medium which absorbs the heat from the junction and dissipates it into the tubular body organ. | 05-28-2009 |
| 20090177258 | Brain Cooling Device and Brain Cooling System Comprising the Device - A brain cooling device is provided to cool the brain sufficiently to the subcortical tissue in a short time. The device includes a cuff ( | 07-09-2009 |
| 20090254161 | METHOD FOR REDUCING MYOCARDIAL INFARCT BY APPLICATION OF INTRAVASCULAR HYPOTHERMIA - Methods and apparatus for preventing myocardial infarction, or lessening the size/severity of an evolving myocardial infarction, by cooling at least the affected area of the myocardium using an intravascular heat exchange catheter. The heat exchange catheter may be inserted into the vasculature (e.g., a vein) and advanced to a position wherein a heat exchanger on the catheter is located in or near the heart (e.g., within the vena cava near the patient's heart). Thereafter, the heat exchange catheter is used to cool the myocardium (or the entire body of the patient) to a temperature that effectively lessens the metabolic rate and/or oxygen consumption of the ischemic myocardial cells or otherwise protects the ischemic myocardium from undergoing irreversible damage or infarction. | 10-08-2009 |
| 20090270955 | THERAPEUTIC HEATING AND COOLING VIA TEMPERATURE MANAGEMENT OF A COLON-INSERTED DUAL BALLOON - Methods and apparatus are provided for heating or cooling a patient's whole body or a selected portion of a patient's body. In one embodiment, the method begins by inserting a catheter having a dual balloon system into the large intestine of a patient. A heated or chilled liquid is conducted through a supply tube of the catheter and into the inner balloon. The liquid is evacuated from the inner balloon through a return lumen of the catheter. The outer balloon conducts heat transfer between the patient's tissues and the inner balloon, and further provides a degree of safety against rupture of the inner balloon. | 10-29-2009 |
| 20090319011 | METHOD AND SYSTEM FOR WARMING OR COOLING A FLUID - The invention is directed generally to a method and system for controlling the temperature of a fluid, i.e., warming or cooling a fluid, and more particularly, to a method and system for warming a fluid to be delivered to the body of a patient. In a preferred embodiment, a method and system for warming a fluid to be delivered into the body of a patient is provided and may include a controller and a fluid delivery-line. | 12-24-2009 |
| 20090326621 | Surgical delivery devices and methods - A surgical device and method for using the same for delivering a cooled solution to a subject can include a reservoir configured to contain a cooled and a tubular probe in communication with the reservoir. In operation, a portion of the tubular probe is inserted through a laparoscopic port and into a desired location within the subject so that the solution in the cooled state can be selectively dispensed from the end of the tubular probe and into the desired location within the subject. | 12-31-2009 |
| 20100016932 | APPARATUS AND METHOD FOR INTERNAL HYPOTHERMIC RADIOPROTECTION - A radioprotection device includes a body positionable in a living organism adjacent to both healthy and unhealthy tissue, where the living organism has a predetermined body temperature. The device includes a cooling element disposed within the body. The cooling element permits cooling of the healthy tissue adjacent to the body to a protective temperature greater than 0° C. and less than the predetermined body temperature during a therapeutic time period during which radiation is applied to the unhealthy tissue. The body discourages cooling of the unhealthy tissue to the protective temperature during the therapeutic time period, thereby providing greater radioprotection to the healthy tissue than the unhealthy tissue during the therapeutic time period. | 01-21-2010 |
| 20100030307 | MULTIPLE LUMEN HEAT EXCHANGE CATHETERS - Catheter devices and methods for intravascular heating and/or cooling of human or veterinary patients. The catheter devices generally comprise catheters having inflow and outflow lumens and at least one curvilinear balloon connected to the inflow and outflow lumens such that heat exchange fluid may be circulated through the balloon(s). The catheter is inserted into the vasculature and heated or cooled fluid is circulated through the balloon(s) to heat or cool blood flowing in heat-exchange proximity to the balloon(s), thereby effecting heating or cooling of all or a portion of the patient's body. | 02-04-2010 |
| 20100114269 | VARIABLE GEOMETRY BALLOON CATHETER AND METHOD - A medical device is provided that may include a catheter body having proximal and distal portions, a fluid injection lumen disposed within elongate body, and a guidewire lumen disposed within the elongate body. A tip portion defining a cavity in fluid communication with the fluid injection lumen may be coupled to the distal end of the guidewire lumen, and an expandable element may be coupled to the distal portion of the catheter body and to the tip portion, such that the expandable element is in fluid communication with the fluid injection lumen. A shaping element may at least partially surround the expandable element, where the shaping element is configurable in a first geometric configuration and a second geometric configuration. | 05-06-2010 |
| 20100137952 | APPARATUSES FOR THERMALLY-INDUCED RENAL NEUROMODULATION - Methods and apparatus are provided for thermally-induced renal neuromodulation. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. In some embodiments, parameters of the neural fibers, of non-target tissue, or of the thermal energy delivery element, may be monitored via one or more sensors for controlling the thermally-induced neuromodulation. In some embodiments, protective elements may be provided to reduce a degree of thermal damage induced in the non-target tissues. | 06-03-2010 |
| 20100152822 | SYSTEM AND METHOD FOR DETERMINING AND CONTROLLING CORE BODY TEMPERATURE - Systems and methods for accurate temperature modification of a patient, or selected regions thereof, including inducing hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette attached to the circulatory flow lines of the catheter, the heat exchange cassette being sized to engage a cavity within a control unit. A temperature measurement scheme for obtaining body core temperature is provided, including methods of obtaining and analyzing temperature data to provide feedback to the control unit for use in controlling the heating and cooling of the heat exchange medium so as to heat or cool a patient to a desired target temperature. | 06-17-2010 |
| 20100198319 | SYSTEM AND METHOD FOR MANIPULATING A TEMPERATURE OF A PATIENT - A system for affecting a temperature of a patient, the system includes: a nose catheter that is adapted to be inserted into a nose upper channel and to receive a first fluid; and a temperature control and fluid supply unit that is adapted to supply the first fluid and control a temperature of the first fluid so as to affect a temperature of a brain of a patient when the nose catheter is inserted into the nose upper channel of a patient and receives the first fluid. | 08-05-2010 |
| 20100204765 | Method and Apparatus for Inducing Therapeutic Hypothermia - Methods and apparatus for delivering therapeutic hypothermia to a patient are provided which may include any number of features. One feature is a hypothermia system comprising a fluid source, a heat exchanger assembly, a catheter in fluid communication with the fluid source, and a pump system configured to infuse hypothermic fluid into a patient cavity and extract hypothermic fluid from the patient cavity. The hypothermia system can infuse and extract fluid automatically from the patient cavity. In one embodiment, the patient cavity is a peritoneal cavity. A safe access device to gain access to the patient cavity is also provided. | 08-12-2010 |
| 20100211140 | METHODS AND DEVICES FOR NON-INVASIVE CEREBRAL AND SYSTEMIC COOLING - A method for providing and adjusting cerebral cooling in response to changes in a physiological parameter. A spray having a boiling point between 38-300° C. is delivered to the surface of a patient's nasal cavities. The spray causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis. A physiological parameter, such as cerebral temperature, changes in cerebral blood flow or brain oxygenation is monitored. The delivery rate of the spray is adjusted in response to the physiological parameter. | 08-19-2010 |
| 20100217361 | Devices and Methods For Controlling Patient Temperature - Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed. | 08-26-2010 |
| 20100234928 | METHOD AND A SYSTEM FOR PROLONGATION OF THE VIABILITY OF A DONOR ORGAN - For post-mortem prolongation of the viability of an organ ( | 09-16-2010 |
| 20100292764 | LAPAROSCOPIC KIDNEY COOLING SHEATH | 11-18-2010 |
| 20100292765 | Apparatus and Method for Cooling the Brain Using a Liquid - Apparatus for cooling the brain comprises a pernasal intubation tube for insertion through one of the nostrils of a patient requiring brain cooling; an inflatable occluder provided the tube for inflation to occlude the nasopharynx of the patient behind the soft palate of the patient thereby to prevent passage of liquid between the nasal cavities and the mouth of the patient; a nostril closure arranged to cooperate with the pernasal intubation tube; an orifice for introduction of a liquid coolant into the nasal cavities; and a liquid vent for insertion in the other nostril of the patient for controlling venting of liquid coolant from the nasal cavities. Also described herein is a method of cooling the brain of a patient in danger of suffering brain damage comprising occluding the air passage leading from the nasal cavities to the mouth cavity of the patient behind the soft palate of the patient and irrigating the nasal cavities of the patient with a coolant liquid. | 11-18-2010 |
| 20100292766 | HEAT EXCHANGE CATHETER WITH MULTI-LUMEN TUBE HAVING A FLUID RETURN PASSAGEWAY - The catheter includes a multi-lumen tube having an outflow portion and an accessory portion. The accessory portion is integrally formed within an interior volume of the outflow portion. The accessory portion has a cross-section smaller than the outflow portion. The outflow portion is offset from the accessory portion such that they are integrally joined. The space between these portions defines a fluid return passageway and the space within the accessory portion defines an accessory passageway. A flexible outer sleeve cooperates with the multi-lumen tube to form a fluid inlet passageway. During operation, an inlet flow of warming fluid flows through the fluid inlet passageway formed between the outer sleeve and the multi-lumen tube. The flow continues around a distal end of the outflow portion of the multi-lumen tube, thus becoming an outlet flow of the warming fluid which is directed through the fluid return passageway. | 11-18-2010 |
| 20100312315 | Apparatus and Method for Cooling the Brain Using a Gas - Apparatus for cooling the brain comprises a pernasal intubation tube for insertion through one of the nostrils of a patient requiring brain cooling, an inflatable occluder provided on the tube to occlude the nasopharynx of the patient behind the soft palate of the patient and to prevent passage of liquid between the nasal cavities and the mouth of the patient; a pressure device for application to the exterior of the nose of the patient so as to apply pressure to the angular vein of the patient thereby to increase venous blood flow to the patient's brain; and a coolant gas supply for supplying coolant gas to at least one of the nasal cavities of the patient. Also described herein is a method of cooling the brain of a patient in danger of suffering brain damage comprising occluding the air passage leading from the nasal cavities to the mouth cavity of the patient behind the soft palate of the patient, applying pressure to an exterior part of the patient's nose so as to exert pressure on the angular vein of the patient thereby to increase venous blood flow to the patient's brain, and supplying a coolant gas to the nasal cavities of the patient. | 12-09-2010 |
| 20100324635 | RAPID COOLING OF BODY AND/OR BRAIN BY IRRIGATING WITH A COOLING LIQUID - Methods and devices are disclosed for providing therapeutic hypothermia using irrigation of the aerodigestive tract with cooled liquids. The disclosed method provides much more rapid therapeutic cooling to lower temperatures than could previously be achieved, thereby improving clinical outcomes. Novel cooling liquids and cooling devices are disclosed for carrying out the method. An external turbulent flow of cooling liquid may also be applied to the exterior of the head to further promote heat exchange. Multiple embodiments of devices are disclosed for performing rapid induction and maintenance of therapeutic hypothermia either in a hospital setting or in the field so that hypothermic treatment can be quickly instituted before significant tissue damage occurs. Methods are also disclosed for targeting brain cooling by irrigating the upper airway/aerodigestive tract, and more generalized cooling by irrigating the esophagus and/or stomach. | 12-23-2010 |
| 20110022136 | APPARATUS AND METHOD FOR PROVIDING ENHANCED HEAT TRANSFER FROM A BODY - Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within a control unit. The control unit includes a heater/cooler device for providing heated or cooled fluid to a heat exchanger in thermal communication with the fluid heat exchange medium circulating to the heat exchange catheter, a user input device, and a processor connected to receive input from various sensors around the body and the system. A temperature control scheme for ramping the body temperature up or down without overshoot is provided. | 01-27-2011 |
| 20110029050 | INTRA-VENTRICULAR BRAIN COOLING CATHETER - A method for cooling of a brain with localized hypothermia allowing for maintenance of the core body temperature is achieved by positioning a cooling catheter within a ventricular cavity of the brain. The cooling catheter includes an inlet channel and an outlet channel providing for a closed flow of a cooling fluid into and out of the cooling catheter. A sack is formed at a distal end of the cooling catheter. The sack is in fluid communication with distal ends of the inlet channel and the outlet channel such that the sack is continually flushed with the cooling fluid as the cooling fluid flows into and out of the cooling catheter. The sack, when filled, takes the shape and size of the ventricular cavity filling the ventricular cavity in which it is positioned. The method further includes cooling the cooling catheter and the ventricular cavity through the closed flow of the cooling fluid through the cooling catheter. | 02-03-2011 |
| 20110034975 | METHODS AND APPARATUS FOR REPAIRING AND/OR REPLACING INTERVERTEBRAL DISC COMPONENTS AND PROMOTING HEALING - Disclosed embodiments provide for treatment of the anulus fibrosus (AF) and intevertebral disc (IVD), including herniated discs, anular tears of the disc, or disc degeneration, while enabling surgeons to contain blood, fluid, proteins, or other materials that are placed into or migrate into or near defective regions of the spine. The invention also concentrates mesenchymal stem cells (MSCs) in the surgical area and increases the area of bone to be fused. Other aspects of the invention may be used to raise the temperature of tissues, including surgical tissues, to stimulate inflammation, thereby stimulating tissue healing. According to these embodiments, the invention places a heating element below the skin and adjacent to the tissue to stimulate the healing thereof. | 02-10-2011 |
| 20110040359 | PORTABLE APPARATUS AND METHOD FOR THE ADMINISTRATION OF HEAT EXCHANGE IN THE LUNGS OF A MAMMAL - An apparatus and method for the delivery and removal of a biocompatible liquid to and from the lungs of a mammal, comprising an ice water container adapted for containing ice water; a biocompatible liquid tank disposed within the ice water container, with the tank adapted for containing a biocompatible liquid; and a biocompatible liquid infusion reservoir disposed within the biocompatible liquid tank. The apparatus also comprises a pump assembly and tube assembly that are in operable connection to the ice water container, biocompatible liquid tank and biocompatible liquid reservoir so as to provide a volume of biocompatible liquid to and from the lungs of a mammal, while breaths of oxygen are supplied using a manually operated air bag. | 02-17-2011 |
| 20110054575 | Methods and Apparatus for Regional and Whole Body Temperature Modification - Methods and apparatus for temperature modification of selected body regions including an induced state of local hypothermia of the brain region for neuroprotection. A heat exchange catheter is provided with heat transfer fins projecting or extending outward from the catheter which may be inserted into selected blood vessels or body regions to transfer heat with blood or fluid in the selected blood vessels or body regions. Another aspect of the invention further provides methods and apparatus for controlling the internal body temperature of a patient. By selectively heating or cooling a portion of the catheter lying within a blood vessel, heat may be transferred to or from blood flowing within the vessel to increase or decrease whole body temperature or the temperature of a target region. Feed back from temperature sensors located within the patient's body allow for control of the heat transfer from the catheter to automatically control the temperature of the patient or of the target region within the patient. The apparatus may include a blood channeling sleeve that directs body fluid over a heat exchanger where the body fluid's temperature is altered, and then is discharged out the distal end of the sleeve to a desired location, for example, cooled blood to the brain for neuroprotection. The catheter may be used alone or in conjunction with other heat exchangers to cool one region of a patient's body while heating another. | 03-03-2011 |
| 20110125232 | Hyperthermia, system, method, and components - An IV pole mountable, therapeutic infusate processing device is incorporated into a hypothermia system to receive therapeutic fluid(s), such as normal saline, peritioneal dialysis solution, or other crystalloid solution, to heat such therapeutic fluid(s) a few degrees centigrade above normal body temperature and to direct the resulting heated infusate to and through a selected anatomical portion of a patients body to raise the temperature of that body portion so as to affect any cancerous or other tumors that may be located therein. The processing device is provided with touch screen controls and visual indicators to facilitate its proper use; while the system further includes temperature and pressure sensors to monitor the hyperthermia processing to insure patient safety. | 05-26-2011 |
| 20110125233 | TISSUE COOLING APPARATUS - An apparatus for cooling a tissue is provided, which includes a temperature control module, a hypothermic catheter, and a cooling member. The temperature control module includes a regulation unit, a temperature sensor, a processor, a display unit, and a refrigerator. The regulation unit is used to regulate a predetermined temperature. The temperature sensor is used to measure a reference temperature of the tissue. The processor is used to calculate a difference between the predetermined temperature and the reference temperature as a feedback to control the output of a cooling source. The display unit is used to display the temperature information. The refrigerator is used to output the cooling source. The hypothermic catheter includes a primary cooling pipe, to transport the cooling source; and a secondary cooling pipe. The cooling member makes contact with the tissue to reduce its temperature. | 05-26-2011 |
| 20110125234 | Devices and Methods For Controlling Patient Temperature - Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed. | 05-26-2011 |
| 20110130811 | Devices and Methods For Controlling Patient Temperature - Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed. | 06-02-2011 |
| 20110166633 | METHOD OF GASTRIC COOLING USING BALLOON CATHETER - A balloon catheter is used in a closed-loop heat exchange system for manipulating the temperature of a patient. The balloon catheter is positioned in the stomach of the patient, and then expanded with a heat exchange fluid delivered through a lumen formed in the shaft of the catheter. The balloon catheter comes into contact with the wall of the stomach, and the stomach substantially conforms around the expanded balloon catheter. The heat exchange fluid is allowed to flow continuously into and out of the balloon catheter. Heat is exchanged between the balloon catheter and the stomach so as to controllably alter the temperature of at least a portion of the patient. Anti-shivering mechanisms and automatic control based on temperature feedback from the patient may be used in connection with the heat exchange system. | 07-07-2011 |
| 20110184501 | Portable Fluid Warming System - The present invention relates to a portable apparatus for warming biocompatible fluids for use in the treatment of injured patients and a method of heating a biocompatible fluid to treat a patient experiencing hypothermia. The present invention may be used to warm intravenous fluids for trauma resuscitation or to warm air from a ventilator circuit. The portable nature of the present invention makes it highly suitable for field applications, such as a forward surgical hospital near a combat zone. | 07-28-2011 |
| 20110224761 | METHOD AND APPARATUS FOR COOLING BIOLOGICAL TISSUE - Exemplary embodiments of apparatus and method for tissue cooling using a plurality of hollow needles to deliver a cooled fluid into the tissue can be provided. For example, a volume and/or temperature of the fluid can be controlled to cool the tissue to a particular temperature or to within a predetermined temperature range. A tissue surface overlying the tissue to be cooled can be pre-cooled using conventional cooling techniques to increase the efficacy of the exemplary procedure. The exemplary method and apparatus can be used, e.g., to disrupt or damage fatty tissue that may then be reabsorbed by the body. | 09-15-2011 |
| 20110264176 | HOT TIP VEIN THERAPY DEVICE - Methods and apparatus for generating vapor within a catheter are provided which may include any number of features. One feature is generating vapor with an electrode array within a catheter. Another feature is sensing an impedance of the electrode array, and adjusting the power delivered to the electrode array to fully generate vapor within the catheter. Another feature is delivering the vapor to a vein of a patient for vein reduction therapy. | 10-27-2011 |
| 20110270368 | Heat Exchange Catheter System - Closed loop heat exchange catheter systems and methods for preparing and using such systems wherein a reservoir or fluid bag is connected to the catheter system and used for at least priming of the system with a heat exchange fluid. | 11-03-2011 |
| 20110282418 | METHODS AND DEVICES FOR COOLING SPINAL TISSUE - Methods, systems, and devices are disclosed for cooling tissue, and in particular for applying therapeutic hypothermia to the spinal canal, tissue disposed within the spinal canal, and nerve roots extending from the spinal canal. Bone screws, intervertebral implants, stabilization rods, spinous process spacers, and other devices are described which define a chamber through which a chilled fluid, expandable gas, or other coolant means can be circulated, delivered, or activated to cool adjacent tissue. The degree of cooling can be regulated using a controller, which can be configured to increase or decrease the cooling effect based on any of a variety of measured or predicted physiological or thermodynamic properties. Methods are disclosed for implanting cooling instruments and for carrying out various treatment regimens that involve cooling tissue using such instruments. | 11-17-2011 |
| 20110307039 | Device, method and system for treatment of sinusitis - A device, method and system for facilitating treatment of a sinusitis condition, including a heat source configured to deliver an output of heated air to the nasal passages of an individual, and a delivery component having a space through which the heated air output of the heat source may pass, the delivery component being configured for placement in the individual's nostrils. The system provides a heated air output source and one or more delivery components configured and sized to fit within the nostril of an individual, which may be used to deliver one or more courses of heated air to a user's sinuses through a nostril. | 12-15-2011 |
| 20120029606 | Cooling device for use with heat-exchange catheter and method of use - Devices, methods and systems for endovascular cooling of human or animal subjects are disclosed. A heat exchange catheter ( | 02-02-2012 |
| 20120046718 | LOCALIZED HYPOTHERMIA TO TREAT WEIGHT DISORDERS - Materials and Methods for producing localized hypothermia in a patient for treatment of a weight disorder (e.g., obesity). | 02-23-2012 |
| 20120089211 | METHODS AND APPARATUS FOR CRYOGENICALLY TREATING MULTIPLE TISSUE SITES WITH A SINGLE PUNCTURE - A method for cryogenically treating tissue comprises piercing the skin, inserting a sheath into tissue, and passing a cryoprobe through the sheath into the tissue. The cryoprobe cools a first region of the tissue, is repositioned in the sheath, and then cools a second region of the tissue. | 04-12-2012 |
| 20120095536 | METHOD AND SYSTEM FOR CONTROL OF A PATIENT'S BODY TEMPERATURE BY WAY OF A TRANSLUMINALLY INSERTABLE HEAT EXCHANGE CATHETER - Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette of any one of several disclosed variations is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within one of various described re-usable control units. The control units include a heater/cooler device, a user input device, and a processor connected to receive input from various sensors around the body and the system. The heater/cooler device may be thermoelectric to enable both heating and 15″ cooling based on polarity. A temperature control scheme for ramping the body temperature up or down without overshoot is provided. The disposable heat exchange cassettes may include an integral pump head that engages with a pump drive mechanism within the re-usable control unit. More than one control unit may be provided to receive the same heat exchange cassette so that, for example, a large capacity control unit can be used initially, and a smaller, battery-powered unit can be substituted once the patient reaches the desired target temperature. | 04-19-2012 |
| 20120095537 | Method and Apparatus for Inducing Therapeutic Hypothermia - Methods and apparatus for delivering therapeutic hypothermia to a patient are provided which may include any number of features. One feature is a hypothermia system comprising a fluid source, a heat exchanger assembly, a catheter in fluid communication with the fluid source, and a pump system configured to infuse hypothermic fluid into a patient cavity and extract hypothermic fluid from the patient cavity. The hypothermia system can infuse and extract fluid automatically from the patient cavity. In one embodiment, the patient cavity is a peritoneal cavity. A safe access device to gain access to the patient cavity is also provided. | 04-19-2012 |
| 20120116487 | Automated Therapy System and Method - An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient. The method includes the following steps: monitoring a patient parameter with a sensor to generate a sensor signal; providing the sensor signal to a controller; and adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient. | 05-10-2012 |
| 20120123509 | Apparatus For Treatment of Reperfusion Injury - An apparatus to minimize and/or eliminate the effects associated with reperfusion injury consisting of an external pump, heat exchanger and control unit creating a flow loop whereby blood is moved from the body via a pump, cooled by an external heat exchanger and reintroduced into a specific location, thereby locally cooling the surrounding tissue and inducing localized hypothermia to minimize tissue injury resulting from ischemia and the effects associated with reperfusion injury as an obstruction is removed and normal blood flow is restored and including the ability to locally measure pressure and temperature in the body. | 05-17-2012 |
| 20120130458 | NEUROMODULATION CRYOTHERAPEUTIC DEVICES AND ASSOCIATED SYSTEMS AND METHODS - Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state. | 05-24-2012 |
| 20120136417 | NEUROMODULATION CRYOTHERAPEUTIC DEVICES AND ASSOCIATED SYSTEMS AND METHODS - Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state. | 05-31-2012 |
| 20120136418 | NEUROMODULATION CRYOTHERAPEUTIC DEVICES AND ASSOCIATED SYSTEMS AND METHODS - Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state. | 05-31-2012 |
| 20120143294 | NEUROMODULATION CRYOTHERAPEUTIC DEVICES AND ASSOCIATED SYSTEMS AND METHODS - Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state. | 06-07-2012 |
| 20120150267 | NEUROMODULATION CRYOTHERAPEUTIC DEVICES AND ASSOCIATED SYSTEMS AND METHODS - Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state. | 06-14-2012 |
| 20120158104 | NEUROMODULATION CRYOTHERAPEUTIC DEVICES AND ASSOCIATED SYSTEMS AND METHODS - Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state. | 06-21-2012 |
| 20120191166 | SYSTEM AND METHOD FOR DETERMINING AND CONTROLLING CORE BODY TEMPERATUE - Systems and methods for accurate temperature modification of a patient, or selected regions thereof, including inducing hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette attached to the circulatory flow lines of the catheter, the heat exchange cassette being sized to engage a cavity within a control unit. A temperature measurement scheme for obtaining body core temperature is provided, including methods of obtaining and analyzing temperature data to provide feedback to the control unit for use in controlling the heating and cooling of the heat exchange medium so as to heat or cool a patient to a desired target temperature. | 07-26-2012 |
| 20120197361 | APPARATUS AND METHODS FOR TREATMENT OF OBSTRUCTIVE SLEEP APNEA UTILIZING CRYOLYSIS OF ADIPOSE TISSUES - Methods, devices, and systems employ cryolysis of oropharyngeal adipose tissues to selectively remove fat cells from the tissues causing obstructive sleep apnea. In various embodiments, a chilled liquid—e.g., a liquid or air—is applied to the target tissue at a temperature and for a duration sufficient to cause cryolysis. | 08-02-2012 |
| 20120197362 | DEVICES FOR COOLING THE NASAL CAVITY - A cerebral cooling device that uses a pressurized source to deliver a fluid that evaporates in the nasal cavity to provide cooling and has a balloon on the distal end that inflates from some of the pressure front the pressurized source. The device includes a nasal catheter having delivery ports located in the distal region and a balloon on the distal end. The proximal end of the catheter is in fluid communication with a pressurized source of a low boiling point fluid. A manifold located between the pressurized source and the catheter distributes the fluid and pressure from the pressurized source to a first lumen of the catheter to inflate the balloon and to a second lumen of the catheter through the delivery ports to cool the nasal cavity. A check valve in the manifold ensures that the fluid and pressure are first delivered to the balloon. | 08-02-2012 |
| 20120203312 | SURGICAL COOLING DEVICE - A surgical device controls the temperature of an organ such as a kidney during minimally invasive surgery. The device includes a number of chambers fed by a fluid port. At least one of the chambers includes one or more baffles so that a cooling fluid entering through the fluid port is selectively distributed in a desired manner about an enclosed organ. The device may be fabricated of materials that can be rolled, folded, or otherwise compressed into a form suitable for delivery to a minimally-invasive surgical site. | 08-09-2012 |
| 20120221082 | Central Nervous System Treatment Device and Methodology - The invention relates to a method of central nervous system pathology treatment through selective hypothermia. Brain and spinal cord cooling is achieved through a closed loop catheter system inserted directly into the cerebrospinal fluid space. The catheter comprises of a portion that dilates in a pulsatile or peristaltic fashion and facilitates circulation of the cooled cerebrospinal fluid. | 08-30-2012 |
| 20120226337 | Method and System for Treatment of a Body of a Mammal in Cardiac Arrest - Method for treatment of a body of a mammal in cardiac arrest, comprising the step of performing a therapeutic hypothermia of the body after the cardiac arrest has occurred, said therapeutic hypothermia comprising:
| 09-06-2012 |
| 20120226338 | DISPOSABLE CASSETTE FOR INTRAVASCULAR HEAT EXCHANGE CATHETER - A heat exchange fluid supply system for supplying a heat exchange fluid to an intravascular heat exchange catheter includes a disposable cassette having a bulkhead and an external heat exchanger, and which is configured to operate in combination with a reusable master control unit. The bulkhead includes a reservoir section and a pump section. The reservoir section is provided with a means to monitor the amount of heat exchange fluid that is in the system. The bulkhead provides the mechanism for priming the system with heat exchange fluid from an external source and for circulating fluid to the catheter in a closed circuit. The pump section is configured to allow for pumping of heat exchange fluid at a constant pressure. | 09-06-2012 |
| 20120265278 | INTEGRATED CRYOSURGICAL SYSTEM WITH REFRIGERANT AND ELECTRICAL POWER SOURCE - A system for treating tissue in a patient includes a body having a cooling fluid supply path and a tissue piercing probe in fluid communication with the cooling fluid supply path. The probe extends distally from the body and is insertable into the tissue through the patient's skin. A cooling fluid source is fluidly coupled with the probe such that when cooling is initiated, cooling fluid flows in the probe thereby cooling the probe and any adjacent tissue. A heater element is in thermal engagement with the cooling fluid source and a power source provides power to the heater element thereby heating the cooling fluid. The power source has sufficient power to heat the cooling fluid to at least a desired temperature but has insufficient power to heat the cooling fluid above a critical temperature which results in rupture of the cooling fluid source. | 10-18-2012 |
| 20120310312 | Precision-Controlled Cooling System for Inducing Diving Reflex and Achieving Safe Hypothermic Central Nervous System Protection - A cooling system for inducing diving reflex and central nervous system protective hypothermia has a cooler, a refrigerant dispenser, a cooling assembly, a controller and an infusing unit. The refrigerant dispenser connects the cooler. The cooling assembly connects the refrigerant dispenser and communicates with the cooler and has a head cooling set. The controller coordinates the refrigerant dispenser and the infusing unit according to the detection of the physical signal including naso-pharyngeal temperature, and cerebral oximetry signal. The infusing unit connects to the controller and has a catheter. When in use, the cooled liquid is pumped into (1) head cooling set covering the face of the patient to induce diving reflex, (2) the infusing unit having an esophago-gastric tube to lower the temperature inside the stomach. Therefore, an effective, precise diving reflex and central nervous system protective hypothermia can be achieved by this invention. | 12-06-2012 |
| 20120323296 | BRAIN COOLING APPARATUS AND BRAIN COOLING DEVICE SUITABLE THERETO - A brain cooling apparatus is provided that can circulate a fluid between a containing unit of a brain cooling device and the brain cooling apparatus while maintaining an appropriate pressure of the fluid in the containing unit, and a brain cooling device suitable thereto also is provided. A control device circulates a physiological saline solution between a storage tank and a cuff by driving a first pump in a direction in which the physiological saline solution flows toward the cuff, and driving a second pump in a direction in which the physiological saline solution flows toward the storage tank. In this state, the control device adjusts the rotation speed of at least the second pump, so that the pressure of the physiological saline solution in the cuff becomes a preset target pressure. | 12-20-2012 |
| 20130006336 | DEVICES AND METHODS FOR CONTROLLING PATIENT TEMPERATURE - Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed. | 01-03-2013 |
| 20130046365 | HEATING/ COOLING SYSTEM FOR INDWELLING HEAT EXCHANGE CATHETER - A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform. | 02-21-2013 |
| 20130060310 | Multi-lumen heat transfer catheter systems - Heat transfer catheter apparatus and methods of making and using same are disclosed wherein fluid connection means is provided between the distal portions of two adjacent, thin-walled, high strength fluid lumens to define a closed loop fluid circulation system capable of controlled delivery of thermal energy to or withdrawal of thermal energy from remote internal body locations. | 03-07-2013 |
| 20130060311 | HEATING/ COOLING SYSTEM FOR INDWELLING HEAT EXCHANGE CATHETER - A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform. | 03-07-2013 |
| 20130073014 | PATIENT TEMPERATURE CONTROL CATHETER WITH OUTER SLEEVE COOLED BY INNER SLEEVE - A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance. | 03-21-2013 |
| 20130079855 | PATIENT TEMPERATURE CONTROL CATHETER WITH HELICAL HEAT EXCHANGE PATHS - A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material. | 03-28-2013 |
| 20130079856 | SELF-CENTERING PATIENT TEMPERATURE CONTROL CATHETER - A patient temperature control catheter includes working fluid supply and return lumens through which working fluid circulates to exchange heat with a patient in whom the catheter is positioned. At least one lumen is defined by plural coils axially spaced from each other. At least a first coil is a large coil that inflates with working fluid to seat against a wall of a blood vessel in which the catheter is positioned, with blood flowing through the coil so as not to block blood flow in the vessel. | 03-28-2013 |
| 20130079857 | SYSTEM AND METHOD FOR DOUBLED USE OF PATIENT TEMPERATURE CONTROL CATHETER - An apparatus for exchanging heat in a patient has a first elongated heat exchange catheter carrying circulating working fluid to and from a heat exchange system and a second elongated heat exchange catheter carrying circulating working fluid to and from the heat exchange system. The apparatus has a connector supporting proximal portions of both catheters while distal portions of the catheters are disposed inside a patient's vasculature to exchange heat with the patient. | 03-28-2013 |
| 20130085554 | GASTRIC, CUTANEOUS, OR PERITONEAL DELIVERY OF FROZEN MIST TO INDUCE THERAPEUTIC HYPERTHERMIA - Peritoneal heat exchange provides the benefit of extremely rapid cooling of the patient's target organs such as the heart and brain as well as facilitating global patient body temperature reduction to therapeutically effective temperatures. The heat exchange medium of the present invention is a chilled gaseous fluid suspension of frozen ice particles. | 04-04-2013 |
| 20130090708 | Endovascular Cooling Catheter System which Employs Phase-Changing Heat Exchange Media - Devices and methods for cooling all or part of the body of a human or animal subject by inserting a heat exchange catheter into the subject's body and infusing into or through the catheter a heat exchange medium that contains liquid phase matter and frozen solid phase matter, wherein at least some of the solid phase matter melts while in the catheter. | 04-11-2013 |
| 20130103126 | Method and Device for Non-invasive Anatomical and Systemic Cooling and Neuroprotection - The present invention provides a method and device for non-invasive anatomical and systemic cooling. The method and device provide for cooling of various bodily fluid- containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of such mucus to the dry fluid results in evaporation and cooling of the anatomical feature and/or systemic cooling, as intended. In this fashion, therapeutic hypothermia may be achieved to provide for neuroprotection of various organs after ischemic insult, such the brain after cardiac arrest. | 04-25-2013 |
| 20130116761 | Rapid Cooling of Body and/or Brain by Irrigating with a Cooling Liquid - Methods and devices are disclosed for providing therapeutic hypothermia using irrigation of the aerodigestive tract with cooled liquids. The disclosed method provides much more rapid therapeutic cooling to lower temperatures than could previously be achieved, thereby improving clinical outcomes. Novel cooling liquids and cooling devices are disclosed for carrying out the method. An external turbulent flow of cooling liquid may also be applied to the exterior of the head to further promote heat exchange. Multiple embodiments of devices are disclosed for performing rapid induction and maintenance of therapeutic hypothermia either in a hospital setting or in the field so that hypothermic treatment can be quickly instituted before significant tissue damage occurs. Methods are also disclosed for targeting brain cooling by irrigating the upper airway/aerodigestive tract, and more generalized cooling by irrigating the esophagus and/or stomach. | 05-09-2013 |
| 20130123888 | HOT TIP LASER GENERATED VAPOR VEIN THERAPY DEVICE - Methods and apparatus for generating vapor within a catheter are provided which may include any number of features. One feature is generating vapor with a fiber optic, laser fiber optic, or fiber optic bundle within a catheter. Another feature is sensing a temperature of the fiber optic, and adjusting the power delivered to the electrode array to fully generate vapor within the catheter. Another feature is delivering the vapor to a vein of a patient for vein reduction therapy. | 05-16-2013 |
| 20130123889 | Apparatus for Preventing Motion Sickness and Related Method - The invention is directed toward a method of reducing motion sickness comprising the steps of introducing cooled gas into a user's ear canal to reduce the temperature of the user's tympanic membrane and vestibular system. The gas is circulated in the user's inner ear, and then exhausted to the atmosphere. The cooled gas induces nystagmus in the user, promotes vestibular desensitization and resistance to motion sickness. The apparatus contemplated for the prevention of motion sickness has an earpiece having a conduit that dispenses cooled gas into the user's ear canal. Gas is provided by a gas source connected to the earpiece with flexible tubing. | 05-16-2013 |
| 20130150929 | METHOD AND SYSTEM FOR CONTROL OF A PATIENT'S BODY TEMPERATURE BY WAY OF A TRANSLUMINALLY INSERTABLE HEAT EXCHANGE CATHETER - Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette of any one of several disclosed variations is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within one of various described re-usable control units. The control units include a heater/cooler device, a user input device, and a processor connected to receive input from various sensors around the body and the system. The heater/cooler device may be thermoelectric to enable both heating and 15″ cooling based on polarity. A temperature control scheme for ramping the body temperature up or down without overshoot is provided. The disposable heat exchange cassettes may include an integral pump head that engages with a pump drive mechanism within the re-usable control unit. More than one control unit may be provided to receive the same heat exchange cassette so that, for example, a large capacity control unit can be used initially, and a smaller, battery-powered unit can be substituted once the patient reaches the desired target temperature. | 06-13-2013 |
| 20130150930 | METHOD AND APPARATUS FOR MODIFYING THE TEMPERATURE OF A PATIENT - A heat exchange fluid supply system for supplying a heat exchange fluid to an intravascular heat exchange catheter includes a disposable cassette having a bulkhead and an external heat exchanger, and which is configured to operate in combination with a reusable master control unit. The bulkhead includes a reservoir section and a pump section. The reservoir section is provided with a means to monitor the amount of heat exchange fluid that is in the system. The bulkhead provides the mechanism for priming the system with heat exchange fluid from an external source and for circulating fluid to the catheter in a closed circuit. The pump section is configured to allow for pumping of heat exchange fluid at a constant pressure. | 06-13-2013 |
| 20130172966 | SYSTEM FOR CONTROLLING THE TEMPERATURE OF A PERSON - A system for affecting a temperature of a patient, the system includes: a nose catheter that is adapted to be inserted into a nose upper channel and to receive a fluid; and a temperature control and fluid supply unit that is adapted to supply the fluid and control a temperature of the fluid so as to affect a temperature of a brain of a patient when the nose catheter is inserted into the nose upper channel of a patient and receives the first fluid; wherein the temperature control and fluid supply unit comprises: a thermoelectric heat pump that is arranged to transfer heat from a cold side to a hot side; a fluid block arranged to be cooled by the cold side and to cool the fluid when the fluid passes through the fluid block; and at least one heat transfer element arranged to transfer heat from the hot side. | 07-04-2013 |
| 20130178923 | Heat Exchange Catheters with Bi-Directional Fluid Flow and Their Methods of Manufacture and Use - Closed loop heat exchange catheters having bi-directional flow heat exchange regions and their methods of manufacture and use. The heat exchange region may be formed of expandable or non-expandable tubular conduit(s) that are configured in a series of loops or coiled configuration defining a supply flow path and a return flow path through which heat exchange medium is circulated. The individual loops of convolutions of the coiled configuration may be the same or different size. In some embodiments, the tubular conduit(s) may be passed through generally transverse bore holes formed in a catheter shaft so that the loops or convolutions of protrude from the catheter shaft. | 07-11-2013 |
| 20130184791 | APPARATUS FOR PERFORMING HEAT TREATMENT - The present invention relates to an apparatus for performing heat treatment of a bodily cavity in a mammal. The apparatus comprises a catheter intended for insertion into said bodily cavity, an inflatable balloon surrounding a distal end of said catheter in a liquid tight manner which balloon is adapted in use of said apparatus to be inflated and dilated in said bodily cavity, control means operatively connected to said balloon by at least one oscillation lumen and being provided with an oscillation assembly adapted to drive a heat transmitting fluid within said apparatus, and heating means adapted to heat said heat transmitting fluid. Said control means are adapted to control pressure and temperature of said heat transmitting fluid. The heating means have a heat emitting portion and a heat receiving portion which is use of the apparatus are positioned in thermal contact with each other, and which are separable from each other. | 07-18-2013 |
| 20130238064 | CRYOTREATMENT DEVICE AND METHOD - Devices and methods for cooling vessel walls to inhibit restenosis in conjunction with medical procedures such as coronary artery angioplasty. One catheter device includes a distal tube region having coolant delivery holes radially and longitudinally distributed along the distal region. In some devices, holes spray coolant directly onto the vessel walls. In other embodiments, a balloon or envelope is interposed between the coolant and the vessel walls and the coolant returned out of the catheter through a coolant return lumen. Some direct spray devices include an occlusion device to restrict blood flow past the region being cooled. Pressure, temperature, and ultrasonic probes are included in some cooling catheters. Some cooling catheters are coiled perfusion catheters supporting longer cooling periods by allowing perfusing blood flow simultaneously with vessel wall cooling. | 09-12-2013 |
| 20130268036 | Apparatus and Method of Treating a Vein with Heat Energy - A method of delivering therapy to a vein. In one embodiment, the method includes the following steps: inserting a structural sheath into the vein, the structural sheath being configured to prevent collapse of the vein due to spasm or via the administration of tumescent anesthesia; advancing a vapor delivery shaft into the catheter sheath; positioning a vapor delivery tip of the vapor delivery shaft distally of the catheter sheath; and delivering vapor to the vein through the vapor delivery tip to, e.g., shrink the vein with the vapor. The invention also includes a vapor delivery catheter system adapted to perform the method. | 10-10-2013 |
| 20130296982 | SURGICAL COOLING DEVICE - Surgical cooling may be implemented by various systems, processes, and techniques. In certain implementations, a surgical cooling device includes a shaft, a cooling assembly, and a mechanical control system. The shaft includes a pair of axial cooling channels extending through its interior. The cooling assembly includes a pair of arms pivotally attached to the shaft and a foldable thermal exchanger coupled to the pair of arms and fluidly coupled to the pair of axial cooling channels. The mechanical control system is adapted to unfold the cooling assembly from a closed position to an open position to allow a coolant to flow through a first of the pair of axial cooling channels, through one or more thermal exchange channels, and out a second of the pair of cooling channels. | 11-07-2013 |
| 20130296983 | MULTIPLE LUMEN HEAT EXCHANGE CATHETERS - Catheter devices and methods for intravascular heating and/or cooling of human or veterinary patients. The catheter devices generally comprise catheters having inflow and outflow lumens and at least one curvilinear balloon connected to the inflow and outflow lumens such that heat exchange fluid may be circulated through the balloon(s). The catheter is inserted into the vasculature and heated or cooled fluid is circulated through the balloon(s) to heat or cool blood flowing in heat-exchange proximity to the balloon(s), thereby effecting heating or cooling of all or a portion of the patient's body. | 11-07-2013 |
| 20130296984 | Automated Therapy System and Method - An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient. The method includes the following steps: monitoring a patient parameter with a sensor to generate a sensor signal; providing the sensor signal to a controller; and adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient. | 11-07-2013 |
| 20130304165 | COMBINATION TREATMENTS - A method of treating a subject in need thereof, is carried out by (a) administering said subject a therapeutic intervention (e.g., an active agent) in a treatment effective amount; and concurrently (b) administering said subject caloric vestibular stimulation in a treatment effective amount, said caloric vestibular stimulation administered so as to enhance the efficacy of said active agent. In some embodiments, the caloric vestibular stimulation is administered as an actively controlled time varying waveform. | 11-14-2013 |
| 20130325090 | HEATING/COOLING SYSTEM FOR INDWELLING HEAT EXCHANGE CATHETER - A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform. | 12-05-2013 |
| 20130331915 | DEVICES FOR COOLING THE NASAL CAVITY - A method for cerebral cooling is described using a cooling assembly, which includes first and second elongate tubular members adapted for insertion into a nasal cavity of a patient through the patient's nostrils. The elongate tubular members each have a proximal end, a distal end, a lumen extending therebetween, and a plurality of ports in fluid communication with the lumen. The cooling assembly also includes a manifold and a reservoir, which contains a pressurized fluid that includes a propellant having a boiling point less than 22° C. The elongate tubular members are inserted into the nasal cavity through the patient's nostrils and pressurized fluid is delivered onto a surface of the nasal cavity by infusing the pressurized fluid from the reservoir through the manifold, into the lumens and through the plurality of ports of the first and second elongate tubular members. | 12-12-2013 |
| 20130338741 | GASTRODUODENAL BALLOON TUBES AND METHODS FOR USE IN LOCALIZED HYPOTHERMIA - Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer). | 12-19-2013 |
| 20140025143 | DEVICES AND METHODS TO REDUCE MYOCARDIAL REPERFUSION INJURY - Devices and methods that mitigate reperfusion injury (RI) in a clinically practical manner so as to avoid significantly increasing time to reperfusion. In general, these systems and methods involve an antegrade approach to deliver a fluid to the myocardium at risk of RI before, during and after reperfusion is established by a percutaneous coronary intervention such as aspiration and stenting. | 01-23-2014 |
| 20140052224 | SYSTEMS AND METHODS FOR SELECTIVE AUTO-RETROPERFUSION ALONG WITH REGIONAL MILD HYPOTHERMIA - Systems and methods for selective auto-retroperfusion along with regional mild hypothermia. In at least one embodiment of a system for providing a retroperfusion therapy to a venous vessel of the present disclosure, the system comprises a catheter for controlling blood perfusion pressure, the catheter comprising a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, and at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen, and adapted to move between an expanded configuration and a deflated configuration, and a flow unit for regulating the flow and pressure of a bodily fluid, and a regional hypothermia system operably coupled to the catheter, the regional hypothermia system operable to reduce and/or regulate a temperature of the bodily fluid flowing therethrough. | 02-20-2014 |
| 20140058484 | SYSTEM AND METHOD FOR DETERMINING AND CONTROLLING CORE BODY TEMPERATURE - Systems and methods for accurate temperature modification of a patient, or selected regions thereof, including inducing hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette attached to the circulatory flow lines of the catheter, the heat exchange cassette being sized to engage a cavity within a control unit. A temperature measurement scheme for obtaining body core temperature is provided, including methods of obtaining and analyzing temperature data to provide feedback to the control unit for use in controlling the heating and cooling of the heat exchange medium so as to heat or cool a patient to a desired target temperature. | 02-27-2014 |
| 20140067027 | HEATING/COOLING SYSTEM FOR INDWELLING HEAT EXCHANGE CATHETER - A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform. | 03-06-2014 |
| 20140094880 | INTRAVASCULAR HEAT EXCHANGE CATHETER WITH MULTIPLE SPACED APART DISCRETE COOLANT LOOPS - A catheter has a series of hollow loops arranged along a tube for carrying working fluid from a heat exchange system to exchange heat with a patient in whom the catheter is advanced. The loops when inflated are transverse to the catheter axis and parallel to each other, and circumscribe a hollow passageway through which blood can flow. Blood also flows around the outer perimeters of the loops. | 04-03-2014 |
| 20140094881 | INTRAVASCULAR HEAT EXCHANGE CATHETER AND SYSTEM WITH RFID COUPLING - A system includes a heat exchange catheter line assembly configured to convey working fluid circulating to and from at least one heat exchange element on an intravascular heat exchange catheter. The system also includes a heat exchange system that itself includes a processor and is configured for fluidly communicating with the heat exchange catheter line assembly to exchange heat with the working fluid. A near filed communication (NFC) member associated with the heat exchange system and an NFC element associated with the heat exchange catheter line assembly are also included. The NFC member is configured to provide the processor with a signal representative of whether the NFC member detects the NFC element. | 04-03-2014 |
| 20140135878 | Method and Apparatus for Peritoneal Hypothermia and/or Resuscitation - Embodiments of the invention provide apparatus, systems and methods for introducing fluids into a body cavity for hypothermic, resuscitative, or other treatment. One embodiment provides an apparatus for introducing fluids into a peritoneal cavity comprising an access device for insertion into subcutaneous tissue, an infusion member and an advancement member. The access device includes a lumen, a proximal end, a tissue penetrating distal end and a stop for controlling the depth of the distal end into tissue. The infusion member includes an infusion lumen, a removal lumen and at least one sensor and is advanceable from a lumen of the access device into the peritoneal cavity. The advancement member is removably positionable in an infusion member lumen and has sufficient column strength to advance the infusion member tip through abdominal wall tissue into the peritoneal cavity. When the advancement member is removed, the infusion member tip is substantially atraumatic. | 05-15-2014 |
| 20140142666 | Cryotherapeutic Devices Having Integral Multi-Helical Balloons and Methods of Making the Same - A cryotherapeutic device having an integral multi-helical balloon section and methods of making the same. A method of forming the cryotherapeutic device can include forming an extruded integral shaft having first and second substantially parallel lumens. The method can further include twisting a distal section of the shaft such that the first and second lumens form intertwined helical portions. The first and second helical portions can be plastically enlarged to form an inflatable body configured to deliver therapeutically effective cryogenic cooling to a treatment site. | 05-22-2014 |
| 20140148881 | APPARATUS AND METHOD FOR CONTROLLING A BODY TEMPERATURE - A device and a method for controlling a temperature of a patient by an infusion of fluid. The device includes at least one supply of infusion fluid; at least one body temperature input adapted to receive the actual body temperature of the patient and at least one additional input adapted to receive at least one additional parameter representing the actual physiological state of the patient. Furthermore, the device includes at least one control unit communicating with the body temperature input, and the additional input and at least one actuator, which is in fluid communication with the supply and which controls at least the actual flow rate and/or actual temperature of the infusion fluid in accordance with at least one control signal of the control unit. The method controls a temperature of a patient by an infusion of fluid using the device. | 05-29-2014 |
| 20140155965 | DEVICES AND METHODS FOR CONTROLLING PATIENT TEMPERATURE - Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed. | 06-05-2014 |
| 20140214139 | TISSUE COOLING CLAMPS AND RELATED METHODS - Methods and devices are disclosed herein that generally involve cooling tissue (e.g., localized cooling of tissue), and in particular applying therapeutic hypothermia to the spinal canal, tissue disposed within the spinal canal, and/or nerve roots extending from the spinal canal. In some embodiments, tissue can be cooled by clamping a cooling instrument to a bone or implant that is proximate to the tissue. The cooling instrument can define a chamber through which a chilled fluid, expandable gas, or other coolant means can be circulated, delivered, or activated to cool adjacent tissue. The degree of cooling can be regulated using a controller, which can be configured to increase or decrease the cooling effect based on any of a variety of measured or predicted physiological or thermodynamic properties. Methods are disclosed for utilizing cooling instruments and for carrying out various treatment regimens that involve cooling tissue using such instruments. | 07-31-2014 |
| 20140277304 | METHOD OF GASTRIC COOLING USING BALLOON CATHETER - A balloon catheter is used in a closed-loop heat exchange system for manipulating the temperature of a patient. The balloon catheter is positioned in the stomach of the patient, and then expanded with a heat exchange fluid delivered through a lumen formed in the shaft of the catheter. The balloon catheter comes into contact with the wall of the stomach, and the stomach substantially conforms around the expanded balloon catheter. The heat exchange fluid is allowed to flow continuously into and out of the balloon catheter. Heat is exchanged between the balloon catheter and the stomach so as to controllably alter the temperature of at least a portion of the patient. Anti-shivering mechanisms and automatic control based on temperature feedback from the patient may be used in connection with the heat exchange system. | 09-18-2014 |
| 20140277305 | Devices, Systems, and Methods for Managing Patient Temperature and Correcting Cardiac Arrhythmia - Methods, devices, and systems for temperature management and ventricular defibrillation are disclosed. Methods, devices, and systems for positioning an electrode in the esophagus of a subject and managing the core body temperature of the subject are disclosed. The use of esophageal heat transfer devices to deliver an electrode for use in delivering an electrical shock to the myocardium is disclosed. | 09-18-2014 |
| 20140343640 | SYSTEMS AND METHODS FOR REDUCING BODY TEMPERATURE - Systems and methods for lowering the body temperature of a patient or inducing hypothermia are generally described. In certain embodiments, the core body temperature of a patient can be lowered by using a heat exchanger. In certain embodiments, the heat exchanger of configured to facilitate transfer of heat from an intubation gas to a cooling fluid prior to delivering the intubation gas to the patient (e.g., to the patient's lungs). | 11-20-2014 |
| 20140343641 | METHODS AND DEVICES FOR NON-INVASIVE CEREBRAL AND SYSTEMIC COOLING - Methods for cerebral cooling are described. Cooling assemblies include elongate tubular members, a reservoir containing a pressurized fluid, and a manifold connecting the reservoir and elongate tubular members. After insertion of the elongate tubular members into the patient's nostrils, a pressurized fluid is delivered onto a surface of the patient's nasal cavity through a plurality of ports in the elongate tubular members. The delivery of the fluid causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis. | 11-20-2014 |
| 20140350648 | BODY TEMPERATURE REDUCTION SYSTEMS AND ASSOCIATED METHODS - Systems and methods for lowering the core body temperature of subject are generally described. In certain embodiments, the core body temperature of a subject can be lowered by using a heat exchanger configured to cool an intubation gas that is transported to the subject via an intubation tube. The intubation tube used to deliver cooled intubation gas to the subject can include one or more features facilitating cooling of the subject. For example, in certain embodiments, the intubation tube may include multiple lumens. In some embodiments, one of the lumens can be used to deliver the relatively cool intubation gas and a second lumen can be used to transport relatively warm gas away from the patient's lungs. In certain embodiments, the system can be configured such that water (e.g., in the form of ice particles and/or liquid mist) can be delivered to the subject via the intubation tube, which can provide an enhanced cooling effect. | 11-27-2014 |
| 20140358201 | APPARATUS AND METHOD FOR PROVIDING ENHANCED HEAT TRANSFER FROM A BODY - Methods and apparatuses for temperature modification of a patient, or selected regions thereof, including an induced state of hypothermia. The temperature modification is accomplished using an in-dwelling heat exchange catheter within which a fluid heat exchange medium circulates. A heat exchange cassette is attached to the circulatory conduits of the catheter, the heat exchange cassette being sized to engage a cavity within a control unit. The control unit includes a heater/cooler device for providing heated or cooled fluid to a heat exchanger in thermal communication with the fluid heat exchange medium circulating to the heat exchange catheter, a user input device, and a processor connected to receive input from various sensors around the body and the system. A temperature control scheme for ramping the body temperature up or down without overshoot is provided. | 12-04-2014 |
| 20150018904 | CRYOTREATMENT DEVICE AND METHOD - Devices and methods for cooling vessel walls to inhibit restenosis in conjunction with medical procedures such as coronary artery angioplasty. One catheter device includes a distal tube region having coolant delivery holes radially and longitudinally distributed along the distal region. In some devices, holes spray coolant directly onto the vessel walls. In other embodiments, a balloon or envelope is interposed between the coolant and the vessel walls and the coolant returned out of the catheter through a coolant return lumen. Some direct spray devices include an occlusion device to restrict blood flow past the region being cooled. Pressure, temperature, and ultrasonic probes are included in some cooling catheters. Some cooling catheters are coiled perfusion catheters supporting longer cooling periods by allowing perfusing blood flow simultaneously with vessel wall cooling. | 01-15-2015 |
| 20150025607 | PATIENT TEMPERATURE CONTROL CATHETER WITH OUTER SLEEVE COOLED BY INNER SLEEVE - A catheter has an inner sleeve through which refrigerant circulates to and from a source of refrigerant. The catheter also has an outer sleeve surrounding the inner sleeve, including a distal end thereof. The outer Sleeve is filled with a frozen biocompatible substance. The refrigerant is separated from the biocompatible substance by one or more walls of the inner sleeve such that the refrigerant is isolated from a patient in whom the catheter is positioned by both the inner sleeve and the frozen biocompatible substance. The refrigerant circulates through the catheter when the catheter is positioned in the patient to maintain the biocompatible substance frozen as heat is transferred from the patient to the biocompatible substance. | 01-22-2015 |
| 20150045858 | Brain Cooling Device for Craniotomy Patient - The present invention relates to a brain cooling device for a craniotomy patient, and more specifically, to a brain cooling device for a craniotomy for cooling the brain so as to prevent damage to the brain after a brain surgery. To this end, the present invention provides the brain cooling device for a craniotomy patient comprising: a cooling portion which is buried in such a manner to come into contact with the brain or the dura mater; and one withdrawal tube, which is one end of the cooling portion that is exposed to the exterior, wherein the withdrawal tube is exposed to the exterior by penetrating through the scalp and the cranium. Otherwise, the present invention provides the brain cooling device for a craniotomy patient comprising: the cooling portion which is buried in such a manner to come into contact with the brain or the dura mater; and an introduction tube and a discharge tube, which are two end portions of the cooling portion that are exposed to the exterior, wherein the introduction tube and the discharge tube are exposed to the exterior by penetrating through the scalp and the cranium. | 02-12-2015 |
| 20150080992 | IMPLANTABLE DEVICES FOR THERMAL THERAPY AND RELATED METHODS - Methods and devices are disclosed herein that generally involve applying thermal therapy to tissue (e.g., localized cooling or heating of tissue), and in particular applying thermal therapy to the spinal canal, tissue disposed within the spinal canal, and/or nerve roots extending from the spinal canal. In some embodiments, tissue can be cooled or heated by implanting a malleable or deformable thermal device in proximity to the targeted tissue. The thermal device can be left in place following surgery to facilitate application of post-surgical thermal therapy. In some embodiments, the thermal device can be removed post-surgery in a minimally- or non-invasive manner. The thermal device can be connectionless or can include penetrable regions, pre-attached tubing, or detachable connectors to facilitate application of cooling or heating means to the device. Methods are disclosed for utilizing thermal devices and for carrying out various treatment regimens that involve cooling or heating tissue using such devices. | 03-19-2015 |
| 20150119962 | TEMPERATURE MANAGEMENT SYSTEMS - Systems and methods for managing patient temperature are disclosed. Temperature management systems that are suitable for an out-of-hospital setting are disclosed. Temperature management systems having a low power requirement are disclosed. Temperature management systems that include a disposable, single-use reservoir are disclosed. | 04-30-2015 |
| 20150320592 | Devices, Systems and Methods for Delivering Thermal Stimulation - The present provides devices, systems and methods useful for stimulating the vestibular and/or nervous systems of an individual with a gas or mixture of gases that has been cooled, heated and/or humidified to produce one or more time-varying thermal waveforms. | 11-12-2015 |
| 20150374538 | COMBINATION TREATMENTS - A method of treating a subject in need thereof, is carried out by (a) administering said subject a therapeutic intervention (e.g., an active agent) in a treatment effective amount; and concurrently (b) administering said subject caloric vestibular stimulation in a treatment effective amount, said caloric vestibular stimulation administered so as to enhance the efficacy of said active agent. In some embodiments, the caloric vestibular stimulation is administered as an actively controlled time varying waveform. | 12-31-2015 |
| 20160000601 | Pain Management Using Cryogenic Remodeling - Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated. | 01-07-2016 |
| 20160022483 | METHOD AND APPARATUS FOR SPINAL COOLING - A method for exchanging heat with a patient's spinal column incident to spinal surgery or to relieve a patient for a hypoxia condition of the spine. A closed loop heat exchange catheter is percutaneously advanced into the retroperitoneal space of the patient or into the vasculature, and then heat exchange fluid is circulated through the catheter to cool the spinal column. | 01-28-2016 |
| 20160058613 | Detecting and Responding to Preshivering - A method of reducing the likelihood of shivering comprises monitoring at least one physiological characteristic in a human or animal subject to detect preshivering and acting to reduce the likelihood of shivering when preshivering is detected. | 03-03-2016 |
| 20160106578 | DEVICES AND METHODS FOR CONTROLLING PATIENT TEMPERATURE - Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed. | 04-21-2016 |
| 20160135987 | Method and Apparatus for Controlling the Inner Temperature of a Patient - The invention relates to a method and apparatus for controlling the inner temperature of a patient, comprising the steps of creating a fluid circuit that comprises a patient and a heat exchanger, the power supply thereto being controlled by a controller; subjecting at least a portion of the fluid in said circuit to the heat exchanger; directing the subjected fluid to and into the patient to control the temperature of the patient; estimating the organ temperature of the patient by a model that has been obtained on a mammal other than the patient; and controlling the power supply to the heat exchanger such that the estimated organ temperature does not exceed a threshold organ temperature, potentially taking into account estimated future organ temperatures. The invention further relates to a method and apparatus for controlling the inner temperature of a patient when subject to whole body hyperthermia, and to a method for obtaining the model. | 05-19-2016 |
| 20160143774 | Automated therapy system and method - An automated therapy system having an infusion catheter; a sensor adapted to sense a patient parameter; and a controller communicating with the sensor and programmed to control flow output from the infusion catheter into a patient based on the patient parameter without removing fluid from the patient. The invention also includes a method of controlling infusion of a fluid to a patient. The method includes the following steps: monitoring a patient parameter with a sensor to generate a sensor signal; providing the sensor signal to a controller; and adjusting fluid flow to the patient based on the sensor signal without removing fluid from the patient. | 05-26-2016 |
| 20160151201 | METHODS AND DEVICES FOR SELECTIVE BRAIN COOLING | 06-02-2016 |
| 20160166719 | THERMAL BACTERIAL DECOLONIZATION | 06-16-2016 |
| 20160175141 | METHOD AND SYSTEM FOR PRODUCING AND DELIVERING AIRLESS MEDICAL ICE SLURRY TO INDUCE HYPOTHEMIA | 06-23-2016 |
| 20160193076 | Endocavity Temperature Control Device | 07-07-2016 |
| 20160193077 | PATIENT TEMPERATURE CONTROL CATHETER WITH OUTER SLEEVE COOLED BY INNER SLEEVE | 07-07-2016 |
| 20160193078 | Apparatus and Method Of Gastric Cooling Using Balloon Catheter | 07-07-2016 |
| 20160199224 | MULTIPLE LUMEN HEAT EXCHANGE CATHETERS | 07-14-2016 |
| 20170231815 | MOUTH COOLER | 08-17-2017 |
| 20190142630 | IMPLANTABLE DEVICES FOR THERMAL THERAPY AND RELATED METHODS | 05-16-2019 |
