| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 604600010 | Component of blood removed (i.e., pheresis) | 61 |
| 20080319369 | Systems and Methods for Removing Fluid and Atherogenic, Thrombotic, and Inflammatory Markers From Blood - Systems and methods for removing fluid and atherogenic, thrombotic and inflammatory (ATI) markers from blood are disclosed. A system for removing fluid and atherogenic, thrombotic and inflammatory markers from blood includes an ultrafiltration module for removing fluid from blood drawn from a patient; and an apheresis module for removing atherogenic, thrombotic, and inflammatory markers from the blood, wherein the ultrafiltration module and the apheresis module form a continuous closed-loop extracorporeal blood circuit. | 12-25-2008 |
| 20090143710 | MARKER FOR NEUROMYELITIS OPTICA - The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO). | 06-04-2009 |
| 20090259162 | System and Method for Plasma Reduced Platelet Collection - A method and apparatus for collecting plasma reduced platelets potentially suspended in a synthetic solution from a donor. Whole blood is drawn from the donor and introduced into a separation chamber. Platelets are extracted from the separation chamber into a container, using, for example, surge (with anticoagulated plasma or a synthetic solution) or push methodologies. The remaining blood components in the separation chamber are returned back to the donor. The steps of drawing whole blood and introducing the whole blood into the separation chamber, extracting platelets from the separation chamber into the container, and returning the remaining components in the chamber back to the donor are repeated. The sequestered platelets in the container are reintroduced into the separation chamber, whereupon a plasma reduced platelet product is extracted. | 10-15-2009 |
| 20100217174 | BLOOD PROCESSING SYSTEM FOR SINGLE OR DOUBLE ACCESS DRAW AND RETURN - A blood processing system is disclosed which is adapted for single or double access draw and return. The blood processing system includes a blood processor for separating blood (or blood components) into one or more components or other components. In one embodiment the blood processor includes an inlet for receiving blood from blood source and an outlet for returning at least one blood component to the source. The processing system includes a first flow path in communication with the inlet, a second flow path in communication with the outlet, a third flow path in communication with a second flow path at two spaced apart locations, a reservoir communicates with the third flow path between the two spaced apart locations, and a flow communication site associated with the second flow path downstream of the spaced apart locations which communication site is adapted to permit communication with the first flow path. | 08-26-2010 |
| 20100292628 | Pressure Monitoring within a Fluid Cassette - A fluid cassette for a blood processing system includes a cassette housing and a rigid structure. The cassette housing defines the structure of the cassette and has a fluid path at least partially extending through it. The fluid path is configured to allow a fluid to pass through the housing. The rigid structure defines a cavity that is in fluid communication with the fluid path. The rigid structure also has an interface for interfacing and/or connecting with a pressure monitoring device. The interface allows the pressure monitoring device to measure the pressure within the fluid path. The cavity has a volume of air located between the fluid path and the interface. | 11-18-2010 |
| 20100298752 | METHOD FOR COLLECTING A DESIRED BLOOD COMPONENT AND PERFORMING A PHOTOPHERESIS TREATMENT - An improved method for separating whole blood into components and collecting a desired blood component. The method allows a desired blood component to be subjected to centrifugal forces within a separator for prolonged periods of time, yielding a cleaner cut and higher yield of the desired blood component. Whole blood is drawn from a source and pumped into a separator, the undesired blood components are removed from the separator at rates so as to build up the desired blood component in the separator. The desired blood component is only removed after a predetermined amount of the desired blood component has built up in the separator. It is preferred that the desired blood component be buffy coat and that the method be used to perform photopheresis treatments. In another aspect, the invention is a method of performing a full photopheresis treatment to treat diseases in a reduced time, preferably less than about 70 minutes, and more preferably less than about 45 minutes. | 11-25-2010 |
| 20100298753 | TARGETED APHERESIS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS - This invention uses “targeted apheresis” to treat rheumatoid arthritis patients. “Targeted Apheresis” is a process whereby the RF and immune complexes responsible for causing the disease symptoms are selectively removed from the blood by passing the blood through a cartridge containing immobilized IgG. The RF and immune complexes are bound out and the cleaned blood is returned to the patient Removal of circulating RF and immune complexes will ameliorate the symptoms of rheumatoid arthritis. | 11-25-2010 |
| 20110021966 | SYSTEMS, METHODS, AND DEVICES FOR BLOOD TREATMENT - A blood treatment device provides a photopheresis treatment using a microfluidic separation channel to separate blood components into layers The layering caused by laminar flow in the microfluidic separation channel allows light to be projected through plasma onto leukocytes without hindrance by erythrocytes | 01-27-2011 |
| 20110034851 | SYSTEM FOR HARVESTING AND DISPENSING A FIBRIN CLOT - A system for harvesting a fibrin clot and depositing that fibrin clot into a wound site during a surgical procedure, the system comprising: | 02-10-2011 |
| 20110054379 | HEMODIALYSIS CATHETER WITH THROMBUS REMOVING DEVICE - The present disclosure provides apparatus and methods for removing thrombus outside of a hemodialysis. The hemodialysis catheter comprises an elongate shaft comprising a plurality of lumens. A first lumen has a first distal port. The first lumen is configured for the flow of a fluid in a first direction. A second lumen has a second distal port proximal to the first distal port. The second lumen is configured for the flow of the fluid in a second direction opposite to the first direction. A third lumen has a third distal port proximal to the second distal port. An elongate device is disposed through the third lumen. The elongate device has an operable member on a distal end or a device to connect to an operable member disposed on the elongate shaft. The operable member is configured to engage and remove thrombus from an exterior surface on the elongate shaft. | 03-03-2011 |
| 20110077574 | SYSTEM AND METHOD TO REGULATE ULTRAFILTRATION - A medical device system including a physiological sensor and ultrafiltration unit senses a physiological signal in a patient and computes a fluid status measurement of the patient using the physiological signal. Ultrafiltration therapy is delivered to the patient according to a therapy delivery control parameter established in response to the fluid status measurement. | 03-31-2011 |
| 20110105982 | FLUID SEPARATION DEVICES, SYSTEMS AND METHODS - A membraneless separation device can be applied to a variety of treatments, such as the ultrafiltration of blood for a patient with end stage renal disease. An ultrafiltration device can include a membraneless separation device, which separates an incoming blood flow into a substantially cytoplasmic body-free plasma flow and remaining fraction, and a dialysate-free second stage, which selectively removes excess fluid, toxins and other substances from the plasma flow and returns the processed plasma to the membraneless separation device. A treatment protocol can include ultrafiltering blood of a patient using the ultrafiltration device and performing a secondary treatment on the blood of the patient at a reduced frequency compared to the ultrafiltering. The membraneless separation device can also be applied to treatment, analysis, and/or exchange of plasma from blood, or combined with conventional dialyzers to perform dialysis on a cytoplasmic body-free plasma fraction. | 05-05-2011 |
| 20110201986 | METHOD FOR ENHANCING IMMUNE RESPONSES IN MAMMALS - The present invention provides a method for enhancing an immune response in a mammal to facilitate the elimination of a chronic pathology. The method involves the removal of immune system inhibitors from the circulation of the mammal, thus, enabling a more vigorous immune response to the pathogenic agent. The removal of immune system inhibitors is accomplished by contacting biological fluids of a mammal with one or more binding partner(s) capable of binding to and, thus, depleting the targeted immune system inhibitor(s) from the biological fluids. Particularly useful in the invention is an absorbent matrix composed of an inert, biocompatible substrate joined covalently to a binding partner, such as an antibody, capable of specifically binding to the targeted immune system inhibitor. | 08-18-2011 |
| 20110201987 | COMBINATION THERAPY FOR PREVENTING OR TREATING ALZHEIMER'S DISEASE, AND KIT THEREFOR - The invention relates to a method for preventing or treating Alzheimer's disease (AE). According to said method, a means for inducing a sequestration of amyloid β (Aβ) into a plasma is administered to a person, and the person is treated by means of an apheresis device comprising a fixed carrier that can come into contact with the blood or plasma flow and comprises a receptor binding an amyloid-β-precurser-protein (APP), the APP being removed from the blood of the person by means of the apheresis device. The invention also relates to a set for carrying out said method. | 08-18-2011 |
| 20120046593 | Laser activated nanothermolysis of cells - Provided herein are methods and systems to increase selective thermomechanical damage to a biological body, such as a cancer cell or cell associated with a pathophysiological condition. The biological body or cancer cell is specifically targeted with nanoparticulates comprising one or more targeting moieties which form nanoparticulate clusters thereon or therewithin. Pulsed electromagnetic radiation, e.g., optical radiation, having a wavelength spectrum selected for a peak wavelength near to or matching a peak absorption wavelength of the nanoparticulates selectively heats the nanoparticulates thereby generating vapor microbubbles around the clusters causing damage to the targets without affecting any surrounding medium or normal cells or tissues. Also provided are methods for treating leukemia and for selectively and thermomechanically causing damage to cells associated with a pathophysiological condition using the methods and system described herein. | 02-23-2012 |
| 20120215150 | Treatment of pre-eclampsia using targeted apheresis - This invention uses “targeted apheresis” to treat pregnant women who are at risk of developing eclampsia. “Targeted Apheresis” is a process whereby certain growth factor receptors (sFlt-1) circulating in the blood of a pregnant woman at risk of developing pre-eclampsia are selectively removed by passing the blood through a cartridge containing immobilized anti-sFlt-1 aptamers. The circulating sFlt-1 is bound out by the immobilized anti-sFlt-1 aptamers and the cleaned blood is returned to the patient. Removal of circulating sFlt-1 will diminish the risk of developing eclampsia during pregnancy. | 08-23-2012 |
| 20120277651 | METHOD FOR ADAPTING THRESHOLD WINDOWS, CONTROL DEVICE, MEDICAL TREATMENT APPARATUS AND MEDICAL MONITORING APPARATUS - The present invention relates to a method of adapting of a second threshold window of at least a second measured variable depending on the change of a first threshold window of a first measured variable, wherein the adaptation is performed by the use of a control unit having been provided and/or configured therefor. The present invention further relates to a control device, a medical treatment apparatus, a medical monitoring apparatus, a digital storage means, a computer program product and a computer program. | 11-01-2012 |
| 20120277652 | Stem Cell Immune Modulation Methods of Use and Apparatus - Methods and apparatus are disclosed co-culturing stem cells with mononuclear cells and/or lymphocytes to modulate their function. The invention also discloses the use of stem cells to educate autoreactive immune cells as a mechanism to treat autoimmune diseases and immune disorder-related diseases, such as diabetes. In one aspect of the invention, bioreactors are disclosed closed for modulating lymphocytes and suppressing autoreactive T cells. The bioreactors can include a chamber having at least one positively charged and/or hydrophobic substrate surface, a population of stem cells attached to the substrate surface, an inlet conduit for introducing lymphocytes into the chamber, and an outlet conduit for extracting treated lymphocytes following co-culturing with the stem cells. | 11-01-2012 |
| 20120323158 | EXTRACORPOREAL IMMUNOADSORPTION TREATMENT - A method for extracorporeally administering selected biologic agents that target soluble cytokines and chemokines via immunoapheresis in order to treat patients with a variety of acute or chronic autoimmune and inflammatory disease states. | 12-20-2012 |
| 20130030345 | Method as well as apparatuses for detecting a permeability or patency in a tube which is inserted in a tube pump - The present invention relates to a method for detecting a permeability or patency of a section of an extracorporeal tube which is inserted in a tube pump, a detection device for executing a method according to the present invention, a medical treatment apparatus which comprises at least one detection device and/or is in signal transmission with it or is connected for signal transmission with it, a digital storage medium, a computer program product as well as a computer program. | 01-31-2013 |
| 20130190674 | USING PHYSIOLOGICAL DATA IN A MEDICAL DEVICE - Systems and methods for using physiological data in a medical device are disclosed. The physiological data may be measured by a vital sign reader and received by a processing circuit associated with the medical device. The processing circuit may automatically adjust the operation of the medical device during a medical procedure based on the physiological data. In some implementations, the processing circuit may mirror a memory partition to a redundant storage device, allowing for uninterrupted execution of the medical procedure in the event of a memory failure condition. | 07-25-2013 |
| 20130197419 | SYSTEMS AND METHODS FOR PERFORMING ONLINE EXTRACORPOREAL PHOTOPHERESIS - Systems and methods for performing online extracorporeal photopheresis of mononuclear cells are disclosed. Whole blood is removed from a patient and introduced through a processing set into a separation chamber to separate the desired cell population from the blood. The separated cell population is processed through the set which is associated with a treatment chamber where the cells are treated. Once treated, the cells are returned to the patient. The processing set remains connected to the patient during the entire ECP treatment procedure and provides an online, sterile closed pathway between the separation chamber and the treatment chamber. | 08-01-2013 |
| 20140350450 | PERFORMING AN APHERESIS PROCEDURE ON A HUMAN SUBJECT WITH IDENTITY INPUT DATA - Systems and methods are provided for performing a medical procedure with respect to a subject. A data storage location of the system is pre-programmed with a plurality of subject data entries, each having subject-specific information associated with it. A user interface receives an identity input from a subject, which corresponds to the identity of the subject. A controller is associated with the database and the user interface, and is programmed to compare the identity input to the subject data entries. If the identity input corresponds to the subject-specific information of a subject data entry, the controller commands a treatment device to perform a medical procedure with respect to the subject. Otherwise, if the identity input does not correspond to the subject-specific information of any of the subject data entries, the controller generates an error signal which prevents the performance of the medical procedure with respect to the subject. | 11-27-2014 |
| 20160199562 | MEDICAL FLUID TREATMENT MACHINES AND RELATED SYSTEMS AND METHODS | 07-14-2016 |
| 604600020 | Erythrocyte | 8 |
| 20080200859 | Apheresis systems & methods - A system for separating fluid components comprising a sealless rotating drum, a rotatable disposable centrifuge cartridge within the drum, a multi-lumen tube fluidly connectable to the cartridge and to an external fluid source, and a control system capable of independently controlling the flow rate within each lumen of the multi-lumen tube. This system may also be used in apheresis procedures for separating blood components from whole blood. The multi-lumen tube may have a ribbon section that unidirectionally fits within a peristaltic block of rollers, wherein each lumen's flow rate may be individually controlled. The system may further include a camera unit operable to observe a separation boundary within the centrifuge cartridge and accordingly adjust the rotation speed to increase or decrease the amount of separation. | 08-21-2008 |
| 20090043237 | METHODS AND DEVICES FOR PROCESSING BLOOD - Methods, devices and device components are presented for blood processing. Particularly, methods, devices and device components are presented for separating blood into blood components and collecting one or more separated blood components, which reduce the incidence of blood vessel infiltration and enhance donor comfort. In one aspect, the invention provides blood processing methods having a return flow rate which decreases systematically during a return time. In another aspect, the invention provides blood processing methods having a removal flow rate, return flow rate or both which are derived from a subject's total blood volume. In another aspect, the present invention provides blood processing methods wherein the fraction by volume of removed blood corresponding to collected components is selected to optimize blood processing efficiency and enhance the purities of collected blood components. | 02-12-2009 |
| 20090209898 | Uninterrupted Flow Pump Apparatus and Method - This invention describes a method for pumping or delivering fluids utilizing a flexible vessel subject to controlled pressures within another pressure vessel. The pressure vessel can be sourced with positive and/or negative (e.g., vacuum) pressure. | 08-20-2009 |
| 20090259163 | Three-Line Apheresis System and Method - A blood processing system for collecting and exchanging blood components includes a venous-access device for drawing whole blood from a subject and returning blood components to the subject. The system may also include three lines connecting the venous access device to a blood component separation device and an anticoagulant source. A blood draw line fluidly connects to the venous-access device to the blood component separation device. An anticoagulant line connected to an anticoagulant source, introduces anticoagulant into the drawn whole blood. A return line, fluidly connected to the venous-access device and the blood component separation device, and returns uncollected blood component to the subject. A draw pump, an anticoagulant pump, and a return pump, respectively control the flows through the draw line, anticoagulant line, and the return line. The blood component separation device separates the drawn blood into a first blood component and a second blood component. The blood component separation device also may be configured to send the first blood component to a first blood component bag. | 10-15-2009 |
| 20110152740 | METHODS AND APPARATUS FOR COLLECTION OF FILTERED BLOOD COMPONENTS - A method and apparatus for red blood collection and filtration is provided wherein a red blood cell collection assembly provides for leukoreduction filtration concurrent with or soon after the red blood cell separation and collection procedure. After red blood cells have been collected, an unwanted blood component, e.g., buffy coat, is diverted into the red blood cell collect line. Operation of a peristaltic pump engaging pump loop allows insertion of a pre-determined quantity of buffy coat into the collect line. The buffy coat can therefore push red blood cells out of the filter and into a collect bag without diluting the collected red blood cells. Alternatively, gravitational force may be used to allow the unwanted blood component to displace red blood cells out of the filter. | 06-23-2011 |
| 20110178453 | System and Method for Optimized Apheresis Draw and Return - A blood processing device includes a venous-access device, a blood component separation device, a return line, a draw line, a first pressure sensor, a second pressure sensor, and a first pump. The first pressure sensor is located on the return line between the blood component separation device and the venous-access device, and determines a first pressure. The second pressure sensor is located on the draw line between the blood component separation device and the venous-access device, and determines a second pressure. The first pump is connected to at least one of the return line and the draw line and controls a flow rate within the connected line based on a subject access pressure determined based upon the first and second pressures. | 07-21-2011 |
| 20130267884 | Systems and Methods for Achieving Target Post-Procedure Fraction of Cells Remaining, Hematocrit, and Blood Volume During a Therapeutic Red Blood Cell Exchange Procedure With Optional Isovolemic Hemodilution - Systems and methods for performing a therapeutic red blood cell exchange procedure are disclosed. In one aspect, a system includes a first flow path for flowing whole blood from a patient. A separator communicates with the first flow path for separating at least red blood cells from plasma. Second and third flow paths communicate with the separator for respectively flowing the separated plasma and red blood cells from the separator. A flow controller is associated with the flow paths to control fluid communication between the flow paths. The controller is configured to perform the procedure to achieve a target fraction of patient cells remaining, target hematocrit, and a target patient fluid volume change at the completion of the procedure based on data input by the operator. | 10-10-2013 |
| 20140148750 | System and Method for Optimized Apheresis Draw and Return - A blood processing device includes a venous-access device, a blood component separation device, a return line, a draw line, a first pressure sensor, a second pressure sensor, and a first pump. The first pressure sensor is located on the return line between the blood component separation device and the venous-access device, and determines a first pressure. The second pressure sensor is located on the draw line between the blood component separation device and the venous-access device, and determines a second pressure. The first pump is connected to at least one of the return line and the draw line and controls a flow rate within the connected line based on a subject access pressure determined based upon the first and second pressures. | 05-29-2014 |
| 604600030 | Leukocyte | 10 |
| 20090118659 | DEVICE ALLOWING SERIAL USE OF CLEAN AND ALTERNATIVE BLOOD FILTERS DURING BLOOD FILTRATION - A device that allows for serial (time) use of clean blood filters during the use of a heart lung machine. The device is comprised of a series of filters and a switching mechanism that allows the new filter to be placed in the blood flow pathway while at the same time removing the old (previous) filter. A clean filter is always available, and filters for specific components of blood or those able to bind and remove specific biochemicals can be used. | 05-07-2009 |
| 20090192434 | METHOD AND MEANS FOR TREATING INFLAMMATORY BOWEL DISEASE - A method of treating inflammatory bowel disease (IBD) comprises providing an intestinal biopsy sample obtained from inflamed tissue of a patient; mechanically treating the sample to obtain a cell suspension; identifying cell surface markers of activated leukocytes selected from T lymphocytes, neutrophil granulocytes, and eosinophil granulocytes in the suspension; raising antibodies against one of more of the activated cells and immobilizing them on a support; providing a column loaded with the support; diverting a portion of the patient's peripheral blood to make it pass through the column before re-infusing it to the patient to make the activated leukocytes couple with antibodies on the support, thereby eliminating them from the blood stream. Also disclosed are corresponding columns and supports, and their use in the method. | 07-30-2009 |
| 20090204051 | Method of removing lymphocyte growth inhibitor - The present invention relates to a method of body fluid treatment for relieving the condition of inhibited lymphocyte proliferation which comprises bringing a mammalian body fluid into contact with an adsorbent comprising a high-molecular compound having a water contact angle within the range of 40° to 98° in the presence of a divalent cation chelating agent in the manner of extracorporeal circulation, or comprises bringing a mammalian body fluid into contact with an active carbon-containing adsorbent in the manner of extracorporeal circulation; and relates to a system for extracorporeal circulation which comprises a body fluid transfer pump, an anticoagulant infusion pump, and a device comprising a container wherein an adsorbent comprising a high-molecular compound having a water contact angle within the range of 40° to 98° is contained, or comprises a body fluid transfer pump, and a device comprising a container wherein an active carbon-containing adsorbent is contained. | 08-13-2009 |
| 20090275874 | Absorbent and Column for Extracorporeal Circulation - The present invention provides an absorbent which can remove cells present in blood including activated leukocytes such as granulocytes and monocytes, and cancer cells as well as can remove cytokines which facilitate the activation of the remaining cells, and further has no concern for pressure loss and has high configuration stability. That is, the present invention provides an absorbent which absorbs the granulocytes and the monocytes in blood, an absorbent for cancer therapy which absorbs an immunosuppressive protein and an absorbent having a bilayer structure of a net and a nonwoven fabric, having a zeta potential of −20 mV or more, as well as a blood circulation column containing any of the absorbents filled therein. | 11-05-2009 |
| 20100081985 | Platelet Additive Solution For Leukoreducing White Blood Cells In Apheresed Platelets - This invention relates to a method of reducing residual white blood cells in an apheresed platelet product. The method includes the steps of adding to the platelet product a solution comprising sodium chloride and magnesium and inducing degradation of the residual white blood cells. | 04-01-2010 |
| 20100210989 | PROCESSING BLOOD | 08-19-2010 |
| 20100268146 | SELECTIVE CYTOPHERESIS DEVICES AND RELATED METHODS THEREOF - The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action. | 10-21-2010 |
| 20100268147 | SELECTIVE CYTOPHERESIS DEVICES AND RELATED METHODS THEREOF - The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action. | 10-21-2010 |
| 20110196280 | SELECTIVE CYTOPHERESIS DEVICES AND RELATED METHODS THEREOF - The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action. | 08-11-2011 |
| 20130261528 | Apheresis Tubing Set - An apheresis tubing set comprises a cryocyte bag for collecting cells separated during apheresis. The cryocyte bag may comprise a mixing compartment in fluid communication with a cell storage compartment, wherein the mixing compartment comprises a cryoprotectant port and a cell sample port and wherein the storage and mixing compartments are in fluid communication via a mix conduit. The cryocyte bag may comprise two or more independent cell storage compartments for collecting two or more aliquots of the cells | 10-03-2013 |
| 604600040 | Plasma | 15 |
| 20090118660 | APPARATUS AND METHOD FOR IN-VIVO PLASMAPHERESIS USING PERIODIC BACKLUSH CONTAINING ANTICOAGULANT - Method for in-vivo plasmapheresis utilizing a plurality of elongated hollow microporous filter fibers periodically interrupt diffusion of blood plasma from a patient, and, for a selected time, directing backflush fluid into the fibers at a pressure and interval sufficient to cleanse the fiber pores, after which plasma diffusion is resumed. The backflush fluid, preferably a normal saline solution, may contain an anticoagulant such as heparin, citrate or NO donor in suitable concentration for systemic anti-coagulation or for treating the fiber for thromboresistance. | 05-07-2009 |
| 20090216173 | Blood detoxification membrane, method for producing same, and use thereof - The invention relates to membranes for haemodialysis, haemofiltration and/or plasmapheresis formed from substituted or unsubstituted cellulose carbamate having a carbamate nitrogen content in the range between 0.1 and 6%. The invention also relates to a method for manufacturing membranes of this type as well as to their use for blood detoxification within the framework of ultrafiltration, high flux dialysis, haemo-diafiltration and plasmapheresis of the blood. | 08-27-2009 |
| 20090259164 | System and Method for Optimized Apheresis Draw and Return - A blood processing device for collecting and exchanging blood components includes a venous-access device for drawing whole blood from a subject and returning unused blood components to the subject. The system may also include a blood component separation device that separates the drawn whole blood into a first blood component and a second blood component. The blood component separation device may also be configured to send the second blood component to a second blood component storage container. The system may use a return line that fluidly connects the venous-access device and the blood component separation device to return the first blood component to the subject. The system may also have a first and second pressure sensor located on the return line. The first pressure sensor may be located between the blood component separation device and the venous-access device and may determine a first pressure within the return line. The second pressure sensor may be located on the return line between the first pressure sensor and the venous-access device and may determine a second pressure within the return line. A pump connected to the return line may control the return flow rate within the return line based on a subject access pressure determined based on the first pressure and the second pressure. | 10-15-2009 |
| 20100022935 | ELECTROMAGNETIC INDUCTION ACCESS DISCONNECT SENSOR - A connection of a patient's vascular system to an extracorporeal blood treatment machine is monitored to ensure the patient's safety during a procedure. The procedure may be hemodialysis, apheresis, plasmapheresis, a coronary by-pass operation, or other procedure. To ensure safe electrical connection, a contact and a return are connected via a conductive connection into the extracorporeal blood circuit. A current is then generated between the contact and the return and is monitored by a non-contact sensor near an access site of the patient. If the current or other quantity related to the current changes significantly, a signal is sent to the machine or a controller to notify a caregiver or a medical professional. The signal may also be sent to immediately stop a blood pump or other component of the machine. | 01-28-2010 |
| 20100042037 | System and Method for Collecting Plasma Protein Fractions from Separated Blood Components - Method and apparatus for separating plasma from blood in a separation vessel and further separator the separated plasma into desired plasma proteins in a plasma separator fluidly connected to the separation vessel to receive the separated plasma. | 02-18-2010 |
| 20100042038 | System and Method for Collecting Plasma Protein Fractions from Separated Blood Components - Method and apparatus for separating plasma from blood in a membrane separator and further separator the separated plasma into desired plasma proteins in a plasma separator fluidly connected to the membrane separator to receive the separated plasma. | 02-18-2010 |
| 20100121246 | MODULAR HEMOFILTRATION APPARATUS WITH INTERACTIVE OPERATOR INSTRUCTIONS AND CONTROL SYSTEM - An apparatus for carrying out selected fluid management and/or renal replacement patient therapy is characterized by an interactive operator control system having operator inputs for selectively changing a panel kit, replacing a filter cartridge, and/or changing to a different patient therapy during a currently running patient therapy, and providing operator instructions for carrying out tasks for completing same. In one embodiment, the interactive operator control system is also characterized by automatically serially identifying different setup steps to be carried out during system setup, displaying the successive steps substantially throughout the system setup as well as displaying on the operator interface screen sequential tasks to be carried out for each of the different setup steps. | 05-13-2010 |
| 20100185134 | Artifical Kidney - Artificial kidney for gradual, and at least semi-continuous, blood treatment, wherein a blood stream is fed from a body of a living human or animal being into the artificial kidney, where anticoagulation is first effected, blood cells and molecules of large and medium molecular weight, such as proteins, are then primarily separated from plasma and fed back to the blood stream, regulating a water and salt balance by diverting excess plasma water and further removing from the blood stream, plasma or plasma water accumulated and toxic substances, by removal of specific electrolytes and waste products and wherein purified or partially purified plasma and plasma water is being carried back to the blood tract of the body. | 07-22-2010 |
| 20100234788 | System and Method for the Re-Anticoagulation of Platelet Rich Plasma - A method for the re-anticoagulation of platelet rich plasma in a blood apheresis system includes priming the blood apheresis system with anticoagulant, such that a volume of anticoagulant is transferred to a PRP container. The method may then transfer the anticoagulant within the PRP container to a red blood cell container, and collect a volume of platelet rich plasma within the PRP container. The platelet rich plasma may be collected in a plurality of cycles. Between collection cycles, the method may transfer a portion of the volume of anticoagulant from the red blood cell container to the PRP container. | 09-16-2010 |
| 20110208106 | METHOD AND APPARATUS FOR ULTRAFILTRATION OF BLOOD - An ultrafiltration filter for an extracorporeal blood circuit having an input for blood withdrawn from a human patient and a blood output for filtered blood to be infused into the patient including: a filter body having a length of at least 20 centimeters (cm) and an interior diameter of no greater than 1.5 cm; an input at a first end of the body to receive the withdrawn blood; an output at a second end of the body to discharge the filtered blood; a filter membrane in the body defining a blood passage through the body, wherein the membrane has an active filter membrane surface area of no greater than 0.2 meters squared (m | 08-25-2011 |
| 20120010554 | METHOD AND APPARATUS FOR CONTROLLING AN EXTRA-CORPOREAL BLOOD TREATMENT IN A MEDICAL DEVICE - Apparatus for controlling an extra-corporeal blood treatment in a medical device, comprising a blood treatment device ( | 01-12-2012 |
| 20120220915 | SYSTEMS AND METHODS FOR SINGLE NEEDLE CONTINUOUS PLASMA PROCESSING - Certain examples describe systems and methods for increasing plasma extracted from donor blood. An example method includes receiving blood extracted from a donor connected to a blood collection machine. The example method includes filtering the blood using a filtration device to remove at least a portion of plasma included in the blood to separate the plasma removed from remaining blood. The example method includes routing the plasma removed for collection. The example method includes re-filtering the remaining blood using a or the filtration device to remove additional plasma from the remaining blood. The example method includes routing the additional plasma removed for collection. | 08-30-2012 |
| 20130012860 | METHODS AND COMPOSITIONS TO PREDICT AND DETECT ACUTE REJECTION - In some embodiments, a method to detect acute rejection in allograft from is described. In some embodiments, a method to anticipate an episode of acute rejection in allografts is also described. In some embodiments, a kit for detecting or predicting acute transplant rejection of a transplanted organ is described. | 01-10-2013 |
| 20130066252 | METHOD FOR DIAGNOSIS FOR MULTIPLE SCLEROSIS INVOLVING ANTI1-RECEPTOR ANTIBODY - The invention relates to a method for diagnosis of multiple sclerosis (MS) wherein, presence or absence of an anti-AT | 03-14-2013 |
| 20130131573 | SELECTIVE ANTI-HLA ANTIBODY REMOVAL DEVICE AND METHODS OF PRODUCTION AND USE THEREOF - An anti-MHC removal device includes a serologically active, soluble MHC moiety covalently coupled to a solid support. Methods of production include covalently coupling the serologically active, soluble MHC moiety to the solid support. Methods of use of the anti-MHC removal device include contacting a biological sample with the device so that antibodies specific for the MHC moiety are removed from the biological sample. The biological sample is then recovered. | 05-23-2013 |
| 604600050 | Single needle | 3 |
| 20140100506 | Three-Line Apheresis System and Method - A blood processing system for collecting and exchanging blood components includes a venous-access device for drawing whole blood from a subject and returning blood components to the subject. The system may include three lines connecting the venous access device to a blood component separation device and an anticoagulant source. A blood draw line fluidly connects to the venous-access device to the blood component separation device. An anticoagulant line introduces anticoagulant into the drawn whole blood. A return line, fluidly connected to the venous-access device and the blood component separation device, returns uncollected blood component to the subject. Each line may have a pump that controls flow through the line. The blood component separation device separates the drawn blood into a first blood component and a second blood component, and may be configured to send the first blood component to a first blood component bag. | 04-10-2014 |
| 20140100507 | PRIMING ANTICOAGULANT LINE FOR BLOOD EXTRACTION - Methods and devices are described for reducing anticoagulant dilution of collected blood components during blood collection. | 04-10-2014 |
| 20150073327 | Tip Configurations for Multi-Lumen Catheter - Multi-lumen catheters with improved tip configurations, including a triple-lumen catheter which may be useful for apheresis. In one variation, the catheter has three lumens with distal openings angularly spaced apart and staggered axially with respect to one another. In another variation, the catheter has two lumens exiting distally and one centrally positioned lumen exiting proximally. A third variation is a catheter with a single distal opening and two proximal openings. The staggered lumen openings along the axial length of the catheter may decrease recirculation while maximizing flow rates. | 03-12-2015 |
| 604600060 | Arterial and venous needles | 1 |
| 20140330193 | ACOUSTIC ACCESS DISCONNECTION SYSTEMS AND METHODS - An access disconnection system includes: an arterial line; a venous line; a transmitter configured to transmit a sound wave in one of the arterial and venous lines when connected to a patient; a receiver configured to receive the sound wave from the other of the arterial and venous lines when connected to the patient; and electronic circuitry coupled to at least one of the transmitter and receiver, the circuitry configured to send a disconnection output indicative of a change in the sound waves received by the receiver from the transmitter sufficient to expect that an access disconnection of one of the arterial line and venous lines has occurred. | 11-06-2014 |
