Entries |
Document | Title | Date |
20080208101 | Diversion Of Emboli During Fluid Circulation - A method of diversion of an embolus during fluid circulation in an extracorporeal circuit which includes the steps of establishing a first circuit ( | 08-28-2008 |
20080221495 | Blood pump system user interface alarm management - User interfaces for medical perfusion systems that provide oxygenation, filtering, and recirculation of blood in connection with various medical procedures are provided. In particular, user interfaces for use with blood pumps that assist in managing alarms commonly encountered during cardiopulmonary bypass surgeries are provided. | 09-11-2008 |
20080221496 | Machine for Extracorporeal Blood Treatment - In a machine for extracorporeal blood treatment, a syringe pump ( | 09-11-2008 |
20080234619 | Portable Hyperthermia Apparatus - An apparatus for implementing hyperthermia may include a reservoir cartridge having an inlet and an outlet, a disposable outflow tube having a reservoir cartridge end connected to the reservoir cartridge at the outlet and an outflow catheter end connected to an outflow catheter, a disposable inflow tube having a reservoir cartridge end connected to the reservoir cartridge at the inlet and an inflow catheter end connected to an inflow catheter, a pump connected to the outflow tube, an integrated computer in communication with at least one disposable temperature sensor and at least one pressure sensor, a thermoelectric heater, proximate to the reservoir cartridge and a housing that contains the reservoir cartridge, the heater and the integrated computer. | 09-25-2008 |
20090076433 | AUTOMATIC PRIME OF AN EXTRACORPOREAL BLOOD CIRCUIT - A system for priming an extracorporeal blood circuit is described. The system includes a fluid circuit with an air venting mechanism, a reversible pump, arterial and venous lines, a prime waste bag and a switchable coupler selectively connecting the arterial and venous lines to the waste bag or alternatively interconnecting the arterial and venous lines. A priming fluid is connected to the circuit and circulated in the circuit under different configurations of the arterial and venous line connections. | 03-19-2009 |
20090088675 | FLUID AND AIR HANDLING IN BLOOD AND DIALYSIS CIRCUITS - An air purging method includes: (a) detecting a low fluid level in a blood circuit indicating a high amount of air in the blood circuit; (b) stopping a blood pump; (c) closing a venous patient line; (d) opening a blood circuit air vent valve and a drain valve; and (e) running the blood pump to meter air through the air vent valve and the drain valve to a drain. | 04-02-2009 |
20090105627 | ACCESS DISCONNECT DETECTION USING GLUCOSE - An access disconnect sensor for a patient undergoing extracorporeal blood processing includes an electrochemical fuel cell or sensor to detect blood leakage. The fuel cell includes circuitry for oxidizing glucose in the blood. The sensor also includes a transmitter to send a signal to a remote receiver that the sensor indicates the presence of blood. The circuitry may include a battery or may use electricity generated by the sensor to send a signal indicating a leak of blood or disconnection of the access needle. | 04-23-2009 |
20090149795 | METHOD AND APPARATUS FOR BLOOD WITHDRAWAL AND INFUSION USING A PRESSURE CONTROLLER - A method and apparatus for controlling blood withdrawal and infusion flow rate with the use of a pressure controller. The pressure controller uses pressure targets based upon occlusion limits that are calculated as a function of flow. The controller has the ability to switch from controlling withdrawal pressure to controlling infusion pressure based upon the detection of an occlusion. The controller distinguishes between partial and total occlusions of the withdrawal vein providing blood access. Depending on the nature of occlusion, the controller limits or temporarily reverses blood flow and, thus, prevents withdrawal vessel collapse or reverses blood flow to quickly infuse blood into the vessel without participation from operator. | 06-11-2009 |
20090156975 | Robust System and Methods for Blood Access - Embodiments of the present invention provide robust systems for the removal and subsequent infusion of blood for measurement purposes, and embodiments of the present invention provide methods of operating such systems and providing capabilities such as predicting and avoiding occlusions and/or bubbles, managing occlusions and/or bubbles if they occur, automatic cleaning of the blood access system, and determining and managing the patency of the blood access site. Such operational challenges can occur during any of several phases of operation of a blood access system. Embodiments of the present invention can effectively incorporate a variety of inputs for the identification of trends consistent with present or pending occlusions. An embodiment of the present invention can be aware of the stage of operation, e.g., withdrawal, infusion, or cleaning, and the prior performance of the system. Embodiments of the present invention can have the ability to identify the location of the problem so that effective procedures can be used to resolve the problem. | 06-18-2009 |
20090182258 | OXIMETRY AND CAPNOGRAPHY SYSTEM FOR USE IN CONNECTION WITH AN EXTRACORPOREAL CIRCULATION PROCEDURE - An oximetry and capnography monitoring system associated to a gas analyzer applied to an ECC procedure, in which a mechanical device based on a tubular circuit is contemplated, such that when the device is connected to the ECC equipment with the main purposes of monitoring the operation of the gas blender, analyzing the oxygenation chamber performance, and checking carbon dioxide outflow from the oxygenation chamber in such a way to prevent collapse within the oxygenation chamber and therefore increasing efficiency throughout the ECC procedure. | 07-16-2009 |
20090259160 | SYSTEM AND COMPOSITION FOR DENDRITIC CELL THERAPY USING PHARMACOLOGICALLY ACTIVE MICROCARRIERS - Monocytes and dendritic cells are grafted to the surface of microparticles for use as a therapeutic device for stimulating a post-injection immune response in vivo. Various embodiments include an injectable composition, an apparatus for grafting cells to the surface of polymer microspheres, and methods of facilitating activation and delivery of an injectable therapeutic device are disclosed. | 10-15-2009 |
20090299260 | TUBE FOR MEDICAL PURPOSES - The present invention relates to a PVC-free tube ( | 12-03-2009 |
20100087770 | MEDICAL APPARATUS FOR EXTRACORPOREAL BLOOD TREATMENT - The medical apparatus has lines that are connected to the vascular system of a patient. To ensure that an accidental escape of blood is identified, a camera is provided and is directed at the extracorporeal blood circuit of the patient. The image signals from the camera are processed in the sense that the color of blood and/or its arrangement in the image area in the camera image is determined, wherein the size of the recorded image area with the color of blood is also evaluated. In this way, an extracorporeal blood loss can be detected and signaled automatically. | 04-08-2010 |
20100145248 | SYSTEM FOR ENRICHING A BODILY FLUID WITH A GAS HAVING AUTOMATED PRIMING CAPABILITIES - This invention discloses a modular system having a base module, a mid-section control module, and a display module for preparing and administering a gas-enriched bodily fluid. Gas-enrichment is achieved by a gas-enriching device which can be in the form of a disposable cartridge. During operation, the gas-enrichment device is placed in an enclosure within the control module to form a fluid pathway for extracorporeal circulation of the bodily fluid. An electronic controller manages the various aspects of the system and executes an automated method for priming the extracorporeal circuit. | 06-10-2010 |
20100145249 | SYSTEM FOR ENRICHING A BODILY FLUID WITH A GAS HAVING A REMOVABLE GAS-ENRICHMENT DEVICE WITH AN INFORMATION RECORDING ELEMENT - This invention discloses a modular system having a base module, a mid-section control module, and a display module for preparing and administering a gas-enriched bodily fluid via an extracorporeal circuit. Gas-enrichment is achieved by a gas-enriching device which can be in the form of a disposable cartridge. The gas-enrichment device has an information recording element disposed thereon. During operation, the gas-enrichment device is placed in an enclosure within the control module. An electronic controller manages the various aspects of the system such as the production of gas-enriched fluid, flow rates, bubble detection, and automatic operation and shut down. The controller is capable of setting a fluid flow rate in the circuit according to a programming based on the information encoded in the information recording element. | 06-10-2010 |
20100168639 | System and Method For Controlling Patient Fluid Balance And/Or Flow Rate For A Therapeutic Plasma Exchange Procedure - Systems and methods for controlling fluid flow during a fluid exchange procedure. In one aspect, a system is provided for controlling a net fluid volume difference of a patient during and/or after a fluid exchange procedure. The system comprises a first flow path for flowing at least a first fluid from the patient and a second flow path for flowing at least a second fluid to the patient. First and second reservoirs are respectively associated with the first and second flow paths. A controller is associated with the first and second flow paths for controlling first and second flow rates and operable to determine an actual flow rate for each first and second fluid and to change a first or second flow rate in response to a difference between at least one of such flow rates and its respective actual flow rate. | 07-01-2010 |
20100185132 | ACCESS DISCONNECTION SYSTEMS AND METHODS USING CONDUCTIVE CONTACTS - An extracorporeal blood system includes: an extracorporeal blood machine including an extracorporeal blood circuit; an access device enabling the extracorporeal blood circuit to be connected to a patient; first and second tube connecting members for connecting respectively to first and second tubes of the extracorporeal circuit; first and second electrodes held, at least in part, by the first and second tube connecting members so as to contact blood flowing through the extracorporeal blood circuit, the first and second electrodes enabling an electrical signal to be injected into the extracorporeal blood circuit; first and second contact members contacting the first and second electrodes respectively; and electronics coupled operably to the first and second contact members for applying the electrical signal, the signal used to monitor the access device. | 07-22-2010 |
20100198129 | FLOW REVERSING DEVICE AND FLUID TREATMENT APPARATUS - The invention relates to a multi-ports extracorporeal medical device ( | 08-05-2010 |
20100228175 | SYSTEM FOR HARVESTING AND DISPENSING BLOOD CLOT - A system for harvesting and dispensing blood clot, the system comprising: | 09-09-2010 |
20100234786 | System and Method for Detection of Disconnection in an Extracorporeal Blood Circuit - The present invention is directed to a dialysis system with a disconnection monitor for determining if a blood line connection to a patient has been disconnected. It includes a blood circuit in fluid communication with a patient and a dialysis circuit, a pressure transducer for generating a signal indicative of a pulse signal in the blood circuit, a cardiac reference signal generator for generating a signal indicative of the patient's pulse and a disconnection monitor. The disconnection monitor includes a pressure transducer data receiver for receiving the signal indicative of the pulse signal in the blood circuit, a cardiac reference signal receiver for receiving the signal indicative of the patient's pulse, and a processor for cross-correlating the signal indicative of the pulse signal in the blood circuit and the signal indicative of the patient's pulse to generate data indicative of a disconnection of the blood line connection to the patient. | 09-16-2010 |
20100262062 | Peripheral Access Devices and Systems - A cannulation system for perfusing a patient's circulatory system, includes an inflow cannula having a first end adapted to be connected to said circulatory system and a second end adapted to be connected to a blood pump, an outflow cannula having a first end adapted to be connected to the blood pump and a second end adapted to be connected to said circulatory system at a location downstream of the first end of the inflow cannula. The flow of blood from the pump is in series with the normal blood flow of the circulatory system of the patient and creates a localized region of hypertension. | 10-14-2010 |
20100298751 | METHOD FOR THE DETERMINATION OF AT LEAST ONE CHARACTERISTIC FIGURE RELATING TO A PATIENT'S GLUCOSE METABOLISM, AND APPARATUS THEREFOR - The present invention relates to a method for detecting at least one characteristic relating to a patient's glucose metabolism, having steps to be performed during an extracorporeal treatment of the patient's blood, particularly during a dialysis treatment, of the extracorporeal addition of glucose and/or insulin and extracorporeal measurement of a glucose concentration and/or an insulin concentration. The invention further proposes a corresponding device. In addition, the invention proposes a method for determining the composition of the dialysate for the extracorporeal treatment of a patient's blood having the steps of determining a glucose level in the patient's blood during the dialysis session and adapting the amount of glucose added to the dialysate or blood based on the glucose level determined. To this end, the invention proposes a corresponding device. The invention further proposes a blood treatment device. | 11-25-2010 |
20110028881 | MEDICAL APPARATUS COMPRISING A MACHINE FOR TREATMENT OF FLUIDS - A medical apparatus comprises a machine for treatment of fluids provided with means ( | 02-03-2011 |
20110028882 | MEDICAL APPARATUS - A medical apparatus comprises a machine ( | 02-03-2011 |
20110034850 | BLOOD TREATMENT APPARATUS AND METHOD - A proposed blood treatment apparatus includes a blood treatment unit, at least one fluid pump and at least one blood pump. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit, while the blood pumps are configured to extract untreated blood from a blood source, e.g. a patient, pass the extracted blood through the blood treatment unit and deliver treated blood to a target vessel, e.g. likewise represented by a patient. Each blood pump includes a pumping chamber, which is separated into a first accumulation container and a second accumulation container by a flexible member. The flexible member is further movable within the pumping chamber so as to vary a volume relationship between the first and second accumulation containers. The second accumulation container is configured to receive an amount of blood treatment fluid to act on the flexible member and thus pump blood from the first accumulation container. | 02-10-2011 |
20110046533 | APPARATUS AND A METHOD FOR MONITORING A VASCULAR ACCESS - An apparatus for monitoring a vascular access includes a dialysis circuit having a venous needle and a blood pump of a peristaltic type which generates oscillatory perturbations in the circuit. An optical sensor, arranged on a patient's body by the venous needle, perceives the perturbations transmitted through the needle and sends a pulsating signal to an analysis device. The absence of a pulsating signal indicates a detachment of the needle. | 02-24-2011 |
20110144556 | LIFE SUPPORT SYSTEM - A life support system such as a heart-lung machine may include a plurality of medical devices a control panel and an excellent control position. The control panel may have separate control elements for operating the medical devices. The control panel may be constructed protruding essentially flat over a floor area of the majority of the medical devices. The control panel may be constructed to protrude in such a manner, that a control element, aligned only with a particular device and with the control position, is assigned to each device. | 06-16-2011 |
20110152739 | EXTRACORPOREAL BLOOD TREATMENT APPARATUS - In an extracorporeal blood treatment apparatus, a user interface ( | 06-23-2011 |
20110178452 | DEVICE FOR EXTRACORPOREAL BLOOD TREATMENT IN SINGLE-NEEDLE OPERATION MODE - A device for the extracorporal blood treatment in a single-needle operating mode includes means for delivering blood into, and means for delivering blood out of means for collecting blood, and a controller for setting the respective delivery rates of the means for the delivery of blood. The operating mode of the means for delivering blood is continually switched between an arterial and a venous phase by the controller, wherein during the arterial phase the delivery rate Q | 07-21-2011 |
20110190679 | EXTRACORPOREAL CELL-BASED THERAPEUTIC DEVICE AND DELIVERY SYSTEM - Extracorporeal cell-based therapeutic devices and delivery systems are disclosed which provide a method for therapeutic delivery of biologically active molecules produced by living cells in response to a dynamic physiologic environment. One embodiment includes long hollow fibers in which a layer of cells are grown within the intraluminal volume or within a double hollow-filled chamber. Another embodiment includes a wafer or a series of wafers providing a substrate onto which cells are grown. The wafer(s) are inserted into a device. A device may deliver a pre-selected molecule, for example, a hormone, into a mammal's systemic circulation and/or may deliver a member of different cell products. The device is adapted to secure viable cells which produce and secrete the pre-selected molecule into blood or fluid. The invention also provides a minimally invasive method for percutaneously introducing into a preselected blood vessel or body cavity the device of the invention. | 08-04-2011 |
20110218474 | APPARATUS FOR THE DESTRUCTION OF TUMOR CELLS OR PATHOGENS IN THE BLOOD STREAM - The invention relates to an apparatus for destroying tumor cells or pathogens in the blood stream, comprising at least one ultrasonic frequency generator ( | 09-08-2011 |
20110230812 | METHOD AND DEVICE FOR RECOGNITION OF PARAVASAL BLEEDING - A method and a device for recognition of paravasal bleeding upon a supplying of blood to a vascular access via a line and/or upon the removal of blood from a vascular access via a line, particularly paravasal bleeding during extra-corporeal blood treatment, such as for hemodialysis, hemofiltration or hemodiafiltration is provided. A device for extra-corporeal blood treatment, particularly for hemodialysis, hemofiltration or hemodiafiltration, comprising a device for recognition of paravasal bleeding is also provided. The method and the device are based on the change of arterial pressure in the arterial branch or the venous pressure in the venous branch of the extra-corporeal circuit being registered during the extra-corporeal blood treatment. If paravasal bleeding occurs during the blood treatment, the positive dynamic pressure on the line leading to the vascular access rises on the venous cannula during the extra-corporeal blood treatment, or the suction pressure on the line leaving the vascular access, such as the arterial cannula during extra-corporeal blood treatment, rises; that is, the suction pressure becomes more negative. The pressure rise begins moderately at first and then becomes increasingly greater. Decisive for the method and the device, therefore, is that pressure changes that come from a pressure level exhibiting a large difference from the reference value find stronger consideration than those that come from a pressure level that exhibits only a minor difference from the reference value. | 09-22-2011 |
20110257576 | PERFUSION SYSTEM WITH RFID - The disclosure pertains to a perfusion system that is easy to set-up, use and monitor during a bypass procedure. In some embodiments, the disclosure pertains to a perfusion system in which at least some of the disposable components used with the perfusion system are configured to be able to communicate set-up and/or operational parameters to the perfusion system. In some embodiments, the disclosure pertains to a blood level sensor that can be used to monitor a blood level or volume within a blood reservoir. The blood level sensor may be utilized in an integrated perfusion system in which the disposable components are configured, as noted above, to communicate with the perfusion system. In some embodiments, the blood level sensor may be utilized with a perfusion system lacking communication with disposables. | 10-20-2011 |
20120010553 | BLOOD COLLECTING SYSTEM - Embodiments include a blood collecting system comprising a scale, a blood agitating system, a blood bag and a tube for extracting blood from a donor. The collecting system comprises, or is connected to, a processor for controlling the scale, the blood agitating system and the amount of blood being extracted from the donor. The processor is arranged to store one or more formulas for calculating an optimum amount of blood that can be donated. The processor can receive information regarding which formula to be used, the parameters necessary for the chosen formula. The processor is arranged to process the parameters in the chosen formula to calculate the amount of blood to be extracted. The processor is arranged to use the result of the calculation to control the collecting system to extract the calculated amount of blood and stop when the scale has detected that the calculated amount has been extracted. | 01-12-2012 |
20120029408 | APPARATUS, SYSTEM AND METHODS FOR EXTRACORPOREAL BLOOD PROCESSING FOR SELECTIVELY COOLING THE BRAIN RELATIVE TO THE BODY DURING HYPERTHERMIC TREATMENT OR TO INDUCE HYPOTHERMIA OF THE BRAIN - A system, apparatus and methods are provided for extra-corporeal blood treatment, and in particular for establishing and maintaining a neck down differential body temperature, while maintaining near normal brain temperatures, to protect the brain from extended or extreme hypothermia or hyperthermia. A blood treatment apparatus and system is provided for differential control of brain temperature and body temperature below the neck. For example, a first bypass circuit with heat exchanger for brain blood circulation maintains a near normal blood temperature, while a second bypass circuit for below the neck blood circulation provides for thermal treatment to induce a temperature differential, e.g. hyperthermia or hypothermia, relative to brain circulation. Such systems and apparatus have application, for example, for diagnostic and therapeutic treatments using hyperthermia, particularly for treatments of extended duration or at elevated temperatures above 42° C., for example, hyperthermia for treatment of cancer, infectious bacterial or viral diseases. | 02-02-2012 |
20120143115 | Cardiopulmonary Apparatus And Methods For Preserving Organ Viability - Apparatus and methods for providing extracorporeal blood circulation and oxygenation control include multi-stage de-airing of blood to provide automated cardiopulmonary replacement to preserve the viability or one or more organs in a clinically dead organ donor or harvested donor organ for subsequent transplantation to an organ receiver patient. | 06-07-2012 |
20120150089 | DEVICE FOR PUMPING BLOOD IN AN EXTRACORPOREAL CIRCUIT - A device for pumping blood in an extracorporeal circuit includes a centrifugal pump that suctions the blood to be pumped via a venous hose line connected to a suction side of the pump and releases it via an arterial hose line connected to a release side of the pump. The device includes a flow sensor that detects a released quantity on the release side of the pump and emits a measurement signal corresponding to the released quantity, a pressure sensor that detects the pressure on the release side of the pump and emits a measurement signal corresponding to the pressure, and an evaluation unit to which the measurement signals of the sensors are fed and which determines a value corresponding to the pressure on the suction side of the pump, taking into consideration the two measurements signals and the rotational speed of the centrifugal pump. | 06-14-2012 |
20120203158 | DEVICE FOR TREATING AN INDIVIDUAL SUFFERING FROM CARDIAC INSUFFICIENCY, CARDIAC ARREST, CIRCULATORY ARREST OR STROKE - The invention relates to a device for treating an individual suffering from cardiac or circulatory arrest or from a stroke, comprising blood withdrawal means (BE) that can be applied to the individual (P), an analysis unit (BA) directly or indirectly connected to the blood withdrawal means for detecting and providing, in the form of a blood analysis result (BAE), at least one characteristic of the blood, directly or indirectly connected to a return means (BR) that can be applied to the individual (P) and is designed to deliver a substance to the individual via the return means (BR). | 08-09-2012 |
20120220914 | Shrouded Sensor Clip Assembly and Blood Chamber for an Optical Blood Monitoring System - An optical blood monitoring system includes a sensor clip assembly and a blood chamber. The blood chamber has an internal flow cavity for extracorporeal blood flow and viewing lenses to enable the sensor clip assembly to monitor the blood when it is mounted on the blood chamber. The sensor clip assembly includes an annular shroud surrounding the LED emitters and another annular shroud surrounding the photodetectors, both for the purpose of blocking ambient light and limiting light piping. The blood chamber includes separate, distinct shroud mating surfaces to engage the shrouds on the sensor clip assembly. | 08-30-2012 |
20120238935 | METHOD FOR ASSESSING A PATIENT'S FLUID STATUS AND/OR SENSITIVITY TO FLUID REMOVAL, CONTROLLER, AND DEVICES - The present invention relates to a method for assessing a patient's sensitivity to fluid removal from the patient's vascular system or to fluid replacement or addition with regard to the patient's hydration state, the method comprising the step of determining a value reflecting the distribution of fluid between at least two distribution spaces of the body of the patient or changes thereof from measured or calculated values, and assessing whether the value fulfils at least one criterion. It also relates to a controller, an apparatus, a device, a digital storage device, a computer program product, and a computer program. | 09-20-2012 |
20120265115 | ACOUSTIC ACCESS DISCONNECTION SYSTEMS AND METHODS - An access disconnection method includes supporting a transmitter including a wireless communication apparatus, a receiver, a portion of an arterial line, a portion of a venous line and electronic circuitry by a member separate from a blood treatment machine. The method further includes operably communicating the electronic circuitry with the transmitter and the receiver, enabling transmission of a wave from the transmitter in one of the arterial and venous lines, enabling receipt of the wave by the receiver in the other of the arterial and venous lines, and enabling a disconnection output to be sent to the blood treatment machine via the electronic circuitry. The disconnection output is indicative of a change in the wave received by the receiver from the transmitter sufficient to expect that an access site disconnection of one of the arterial and venous lines has occurred. | 10-18-2012 |
20120296253 | HAEMODIALYSIS MACHINE RETROFIT AND CONTROL INSTALLATION AND USE THEREOF FOR THE TREATMENT OF PROLIFERATIVE DISORDERS - A haemodialysis machine retrofit and control installation including an intake-flow blood glucose sensor and an intake-flow blood glutamine sensor, a return-flow blood glucose sensor and return-flow blood glutamine sensor, a dialysate glucose- and glutamine controller, a central control unit connected to the blood glucose- and glutamine sensors, the dialysate glucose- and glutamine controllers for regulating the glucose and glutamine levels in the dialysate to obtain required blood-glucose and glutamine concentrations at the return-flow blood glucose- and glutamine sensors and an electroencephalograph (EEG) monitor providing the central control unit with information pertaining to spontaneous electro-cerebral activity to initiate raising of glucose and glutamine levels. Also disclosed is a method of treating a proliferative disorder in a human or animal, by reducing via a retrofitted haemodialysis machine blood-glucose or glutamine concentrations in the human or animal body for a pre-defined period of time. | 11-22-2012 |
20120323157 | Method for Blood Withdrawal and Infusion Using a Pressure Controller - A method and apparatus for controlling blood withdrawal and infusion flow rate with the use of a pressure controller. The pressure controller uses pressure targets based upon occlusion limits that are calculated as a function of flow. The controller has the ability to switch from controlling withdrawal pressure to controlling infusion pressure based upon the detection of an occlusion. The controller distinguishes between partial and total occlusions of the withdrawal vein providing blood access. Depending on the nature of occlusion, the controller limits or temporarily reverses blood flow and, thus, prevents withdrawal vessel collapse or reverses blood flow to quickly infuse blood into the vessel without participation from operator. | 12-20-2012 |
20130072844 | USE OF ENTRAINED NEUTROPHILS TO TREAT METASTATIC AND MICROMETASTATIC DISEASE IN AT RISK PATIENTS - The present invention relates generally to compositions and methods for treating cancer patients with a poor prognosis, and to therapeutic modalities for improving prognosis by combating metastasis and abrogating chemoresistance in cancer cells. In particular, the invention relates to the role of white blood cells, i.e. neutrophils and neutrophil-like cells, in preventing the spread of cancer from a primary tumor to secondary locations in the body. The invention provides methods for reducing or delaying the spread of metastatic cancer cells in a patient at risk for metastatic tumor development, at risk for metastatic relapse, i.e. prophylactic methods, and treating patients suffering from metastatic tumors. | 03-21-2013 |
20130150766 | METHOD AND DEVICE FOR DETECTING A CONFIGURATION OF WITHDRAWAL AND RETURN DEVICES - A device is arranged to detect a configuration of withdrawal and return devices ( | 06-13-2013 |
20130226064 | Portable medical apparatus for cardiopulmonary aid to patients - A portable medical apparatus ( | 08-29-2013 |
20130245530 | MEDICAL APPARATUS HAVING A SOCKET UNIT FOR CONNECTION OF A DEVICE FOR SUPPLYING MEDICAL FLUIDS, AND DEVICE FOR SUPPLYING MEDICAL FLUIDS HAVING A PLUG UNIT FOR CONNECTION TO A MEDICAL APPARATUS - A medical apparatus includes a socket unit for connection to a plug unit belonging to a device for supplying medical fluids for a blood treatment apparatus, the medical apparatus being in particular an extra-corporeal blood treatment apparatus such for example as an extra-corporeal dialysis apparatus or an apparatus for peritoneal dialysis, or an apparatus for filling the device for supplying medical fluids. A device for supplying medical fluids for a blood treatment apparatus, which has a plug unit for connection to a socket unit of a medical apparatus, is also described. The socket unit and the plug unit are characterised in that a safe and secure fluid-tight connection can easily be made with the two units between the device for supplying medical fluids and, on the one hand, the blood treatment apparatus or, on the other hand, the apparatus for filling the device for supplying medical fluids. | 09-19-2013 |
20130245531 | MEDICAL APPARATUS WITH A SOCKET UNIT FOR THE CONNECTION OF A DEVICE FOR SUPPLYING MEDICAL FLUIDS - A medical apparatus includes a socket unit for connecting a plug unit of a device for supplying medical fluids, in which the medical apparatus is in particular an extracorporeal blood treatment apparatus, for example an extracorporeal dialysis apparatus or an apparatus for peritoneal dialysis, or an apparatus for filling the device for supplying medical fluids. The socket unit comprises connection pieces for the connection of connectors of a plug unit, so that a flow connection can be produced for supplying or discharging a fluid. The connection pieces are surrounded by connection parts thereby forming rinsing chambers, in which the rinsing chambers are closed by closure pieces, said closure pieces being part of a closure body which is disposed rotatably on the socket unit. | 09-19-2013 |
20130317408 | MEDICAL DEVICE FOR EXTRACORPOREAL BLOOD TREATMENT COMPRISING PLURAL SENSOR UNITS - The invention relates to a medical device for extracorporeal blood treatment comprising an extracorporeal blood circulation having at least one tube and at least two sensor units measuring on the tube with different operating principles, wherein portions of the tube are adapted to be coupled to the at least two sensor units for measurement. According to the invention, each sensor unit consists of a sensor-specific component and a sensor-neutral component, wherein the sensor-neutral components of the sensor units are formed to be identical whereas the sensor-specific components are different in response to the operating principle and comprise a respective specific sensor system. Furthermore, for each sensor unit a sensor-neutral component is mounted on a sensor-specific component, wherein when being introduced and fixed in a sensor-neutral component a portion of the tube is adapted to be coupled to the sensor system of the sensor-specific component located there beneath so that the sensor system can carry out a measurement at the tube. | 11-28-2013 |
20130338559 | BLOOD PUMP SYSTEMS AND METHODS - The present invention relates to a rotary blood pump with a double pivot contact bearing system with an operating range between about 50 mL/min and about 1500 mL/min is described, wherein the force on the upper bearing is less than 3N during operating speeds up to 6000 rpm. The invention also relates to a method of using a blood pump system for persistently increasing the overall diameter and lumen diameter of peripheral veins and arteries by persistently increasing the speed of blood and the wall shear stress in a peripheral vein or artery for period of time sufficient to result in a persistent increase in the overall diameter and lumen diameter of the vessel is provided. The blood pump system may also be used to reduce venous hypertension in a lower extremity and increasing the rate of healing of lower extremity venous ulcers in patients is provided. The blood pump system includes a blood pump, blood conduit(s), a control system with optional sensors, and a power source. The pump system is configured to connect to the vascular system in a patient and pump blood at a desired rate. The pumping of blood is monitored and adjusted, as necessary, to maintain the desired elevated blood speed and wall shear stress, and the desired pulsatility in the target artery or vein in order to optimize the rate and extent of the persistent increase in the overall diameter and lumen diameter of the target peripheral artery or vein or to result in a reduction in venous blood pressure in the treated lower extremity or healing of the lower extremity venous ulcer. | 12-19-2013 |
20140074007 | CLOSED-CIRCUIT DEVICE AND METHODS FOR ISOLATION, MODIFICATION, AND RE-ADMINISTRATION OF SPECIFIC CONSTITUENTS FROM A BIOLOGICAL FLUID SOURCE - The present invention relates to a method and apparatus for the isolation, modification and re-administration of a molecule or biomolecule, or a class of biomolecules, from the body fluid of a mammal via an extracorporeal closed circuit device. The device is able to capture and modify the biomolecule by the covalent or non-covalent attachment of a secondary molecule or protein, by cross-linking the captured molecule, or by altering the structure of the molecule (for example, by deglycosylation, peptide cleavage, or aggregation). The apparatus can be used to return the modified molecule or biomolecule to the mammalian subject. The device and methods may be utilized for the patient-specific diagnosis and/or treatment of a disease state which presents an associated molecule or protein in plasma or any other fluidized physiological system. | 03-13-2014 |
20140081193 | METHOD AND SYSTEM FOR ADJUSTING ROTATION SPEED OF AN EXTRACORPOREAL THERAPEUTIC DEVICE - An extracorporeal therapeutic device automatically controls a rotation speed of a centrifuge for processing whole blood. Separation of whole blood components is achieved with minimal thermal contribution to blood temperature from the motor control mechanism that rotates the centrifuge and from aerodynamic drag on the rotating centrifuge. | 03-20-2014 |
20140303542 | Method and device for treating cancer - A method and device treats cancer where blood from a cancer patient passes through an array of passageways within an interior of a chamber. The passageways include wells having porous membrane wall portions that enable a molecular-sized activating agent in a carrier fluid that enhances an immune response to pass through these porous wall portions. Pore size is such to allow the molecular-sized activating agent in the interior of the chamber to enter the wells yet prevents immune cells and cancer cells in the wells to pass through the porous wall portions into the interior of the chamber. Blood is retained in the wells so that it remains in contact with the immune cells and cancer cells for a predetermined period sufficient to enhance an immune response. Then the cells with an enhanced immune response are return to the patient. | 10-09-2014 |
20150045712 | Blood Feeding Flow Rate-Controlling Device and Extracorporeal Circulation Device - A blood supply flow rate controlling device ( | 02-12-2015 |
20150306293 | DETECTING PRESSURE PULSES IN A BLOOD PROCESSING APPARATUS - A monitoring device ( | 10-29-2015 |
20150335805 | METHOD FOR ASSESSING A PATIENT'S FLUID STATUS AND/OR SENSITIVITY TO FLUID REMOVAL, CONTROLLER, AND DEVICES - The present invention relates to a method for assessing a patient's sensitivity to fluid removal from the patient's vascular system or to fluid replacement or addition with regard to the patient's hydration state, the method comprising the step of determining a value reflecting the distribution of fluid between at least two distribution spaces of the body of the patient or changes thereof from measured or calculated values, and assessing whether the value fulfils at least one criterion. It also relates to a controller, an apparatus, a device, a digital storage device, a computer program product, and a computer program. | 11-26-2015 |
20160038667 | SYSTEMS AND METHODS FOR DESTROYING CANCER CELLS IN BLOOD - An apparatus for destroying cancer cells in blood includes a vessel for accepting a flow of blood of a patient through the vessel, and a sound energy source coupled with the vessel for generating sound energy at a resonant sweep frequency that causes cancer cells, within the flow of blood in the vessel, to act as cavitation nuclei and implode without implosion of other cells not resonant with the resonant sweep frequency. A method for destroying cancer cells in blood includes circulating blood from a patient through a vessel coupled with a sound energy source and exposing the blood, when passing through the vessel, to sound energy at a resonant sweep frequency to make cancer cells therein act as cavitation nuclei and implode without implosion of other cells not resonant with the resonant sweep frequency. | 02-11-2016 |
20160067472 | CATHETER ADAPTER APPARATUS - A catheter adapter apparatus includes an adapter body. The adapter body includes a fluid source end adapted for connection to a fluid source and having an internal bore to transfer the fluids supplied by the fluid source, and a catheter end for connection to a catheter tube. The catheter end includes first and second members. Each of the first and second members is adapted for reception within corresponding lumens of the catheter tube. At least the first member defines an internal bore in fluid communication with the fluid source end to transfer the fluids supplied by the fluid source. | 03-10-2016 |
20160095971 | METHOD AND DEVICE FOR MONITORING EXTRACORPOREAL BLOOD FLOW - A method and a device for monitoring an extracorporeal blood flow during an extracorporeal blood treatment with an extracorporeal blood treatment device. The extracorporeal blood treatment device may include the device for monitoring an extracorporeal blood flow. The arterial and/or venous patient access is monitored with a first and a second method, each of which there is a check for a presence of at least one criterion that is characteristic of a condition of the vascular access that is not in proper order, the criteria for the first and second methods being distinguished from one another. A blood pump, which is preferably an occlusion blood pump, is stopped once the presence of the at least one criterion of the first method has been established, while a venous cut-off unit remains open. Once the blood pump has been stopped, the presence of the at least one criterion is checked with the second method. The venous cut-off unit is not closed until the at least one criterion for the second method is present. Otherwise the blood pump is restarted to continue the blood treatment. | 04-07-2016 |
20160158431 | FILTERING OF PRESSURE SIGNALS FOR SUPPRESSION OF PERIODIC TABLES - A filtering device receives a pressure signal (P) from a pressure sensor in a fluid containing system, the pressure signal (P) comprising first pulses originating from a first periodic pulse generator and second pulses. The device acquires a reference signal which is indicative of a current operating frequency of the first periodic pulse generator. The device identifies, based on the reference signal, a plurality of harmonics ( | 06-09-2016 |
20180021219 | BLOOD COLLECTION DEVICE, BLOOD COLLECTION SET, BLOOD COLLECTION METHOD | 01-25-2018 |
20190143023 | Removal Of Microbubbles Through Drip Chamber Nucleation Sites | 05-16-2019 |
20190143026 | DETECTION OF A DISRUPTION OF A FLUID CONNECTION BETWEEN TWO FLUID CONTAINING SYSTEMS | 05-16-2019 |