| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 552540000 | Carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system is a member of an acyclic chain of six or more uninterrupted carbons (e.g., sterols, etc.) | 23 |
| 20100234624 | USE OF 20(S)-PROTOPANAXADIOL IN MANUFACTURE OF ANTIDEPRESSANTS - The invention provides the novel use of 20(S)-protopanaxadiol in the preparation of medicaments for the treatment of depressive psychiatric disorders. The pharmacological test results indicated that the compound could remarkably increase the level of NE, 5-HT and HAV in the brains of model rats having depressive disorders, remarkably enhance tremors induced by 5-hydroxytryptophan (5-HTP) and behavioral effects induced by levodopa, and inhibit the re-uptake of 5-HT and NA. | 09-16-2010 |
| 20160068562 | Raman Tag - The present invention provides novel Raman tags for exploring membrane interactions in cells. The tags comprise a phenyl diyne probe where in the dyine is capped with the phenyl group. Methods for using the tags are also provided. | 03-10-2016 |
| 552541000 | Oxygen bonded directly at the 1-, 2-, or 4-position | 3 |
| 20100168451 | PREPARATIVE METHOD OF DIHYDROCUCURBITACIN F-25-O-ACETATE AND THE USE THEREOF IN THE MANUFACTURE OF MEDICAMENTS FOR TREATING CANCERS - A method for producing dihydrocucurbitacin F-25-0-acetate consisting of the steps as followed: percolating radix hemsleyae using acetone as solvents to obtain extract; eluting the extract in silica gel column using chloroform: methanol as eluting agent (gradient) to obtain the crude; recrystallizating the crude using methanol or ethanol to obtain di-hydrocucurbitacin F-25-O-acetate (purity:>98%). And the use of dihydrocucurbitacin F-25-O-acetate in the manufacture of medicaments for treating cancers of liver, lung, stomach, larynx, prostate and leukemia. | 07-01-2010 |
| 20110082307 | RECOVERY OF PHYTOSTEROLS FROM RESIDUAL VEGETABLE OIL STREAMS - There is disclosed a method for isolation and purification of phytosterols from tall oil pitch comprising the steps of: a) contacting the tall oil pitch with a solvent to form a tall oil solvent mixture; b) separating the tall oil pitch solvent mixture in at least two separate streams wherein one process stream is enriched in acidic pitch components and a second stream enriched in free- and bound sterols in the form of steryl esters; c) subjecting the stream enriched in free- and steryl esters to treatment with an alcohol under transesterification conditions wherein a reaction mixture is formed and sterols comprising the steryl esters are liberated as free sterols; and d) separating the free sterols from the reaction mixture of step c) by crystallization and extraction with one or more solvents. There are disclosed free fatty acids and resin acids separated from the tall oil pitch. Moreover, there is disclosed a manufacture and separation of fatty acid alkyl esters by the method. | 04-07-2011 |
| 20120190871 | TRITERPENOID COMPOSITION OF ANTRODIA CINNAMOMEA, PREPARATION AND ANALYSIS METHOD THEREOF - Disclosed are the isolation, purification and analysis of the triterpenoid compositions (including ergostane and lanostane) in the fruiting body of | 07-26-2012 |
| 552544000 | Exactly one oxygen bonded directly to the cyclopentanohydrophenanthrene ring system (e.g., cholesterols, cholestanols, stigmasterols, etc.) | 18 |
| 20090209773 | Method and device for purifying high melting organic raw products or compund mixtures by means of fractionated melting crystallisation from solvent mixtures - This invention relates to a method and a device for purifying and/or separating preferably high melting organic raw products or compound mixtures containing, in particular, high melting and/or degradable sterols, by layer crystallisation on first heat exchanger surfaces. The raw product is received in a solvent or solvent mixture, and then brought into contact with heat exchanger surfaces. The desired product crystallises on the heat exchanger surfaces by slow cooling. Solvent evaporating during the crystallisation or sweating process is condensed and returned to the mixture. | 08-20-2009 |
| 20100105933 | LIPID NANOPARTICLE BASED COMPOSITIONS AND METHODS FOR THE DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES - The present invention relates to novel cationic lipids, transfection agents, microparticles, nanoparticles, and short interfering nucleic acid (siNA) molecules. The invention also features compositions, and methods of use for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity in a subject or organism. Specifically, the invention relates to novel cationic lipids, microparticles, nanoparticles and transfection agents that effectively transfect or deliver biologically active molecules, such as antibodies (e.g., monoclonal, chimeric, humanized etc.), cholesterol, hormones, antivirals, peptides, proteins, chemotherapeutics, small molecules, vitamins, co-factors, nucleosides, nucleotides, oligonucleotides, enzymatic nucleic acids, antisense nucleic acids, triplex forming oligonucleotides, 2,5-A chimeras, dsRNA, allozymes, aptamers, decoys and analogs thereof, and small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), short hairpin RNA (shRNA), and RNAi inhibitor molecules, to relevant cells and/or tissues, such as in a subject or organism. Such novel cationic lipids, microparticles, nanoparticles and transfection agents are useful, for example, in providing compositions to prevent, inhibit, or treat diseases, conditions, or traits in a cell, subject or organism. The compositions described herein are generally referred to as formulated molecular compositions (FMC) or lipid nanoparticles (LNP). | 04-29-2010 |
| 20110184197 | EFFECTIVE HYDROGENATION PROCESS - The invention relates to an effective process for producing plant stanol by hydrogenating plant sterol in an organic solvent at a hydrogen pressure of 1-200 bar in the presence of a hydrogenation catalyst. | 07-28-2011 |
| 20110224447 | Novel Lipid Nanoparticles and Novel Components for Delivery of Nucleic Acids - The instant invention provides for novel lipid nanoparticles and novel lipid nanoparticle components (specifically cationic lipids) that are useful for the delivery of nucleic acids, specifically siRNA, for therapeutic purposes. | 09-15-2011 |
| 20120108833 | PROCESS FOR THE PREPARATION OF PHYTOSTERYL FERULATE - A method is provided for controlling the operating temperature of a catalytic reactor using a closed-loop system that provides for varying the reactor input and other operating parameters in order to maintain the operating temperature of the reactor at or near the initial setpoint temperature for operation of the reactor. In one example, maximum and minimum operating temperatures with a catalytic partial oxidation reactor are controlled, as well as maintaining control over the corresponding minimum required ratio of oxygen atoms to carbon atoms, such that the operating temperature within the reactor is maintained below the material limits but above threshold temperatures for coking. | 05-03-2012 |
| 20130345454 | A PROCESS FOR THE PREPARATION OF PHYTOSTERYL FERULATE - The present invention relates to a synthetic method for the preparation of phytosteryl ferulate using ferulic acid and phytosterols (isolated from soybean oil deodorizer distillate) comprising of (a) acetylation of ferulic acid to ferulic acid acetate; (b) esterification of ferulic acid acetate with phytosterols to obtain phytosteryl ferulate acetate; (c) deprotection of phytosteryl ferulate acetate to phytosteryl ferulate. The phytosteryl ferulate was evaluated for hypocholesteremic activity in hamsters in comparison with that of natural oryzanol isolated from rice bran oil soap stock. This study confirmed that the phytosteryl ferulate significantly lowers the elevated cholesterol levels and also interferes with the absorption of cholesterol and the effect is comparable with that of natural oryzanol and is useful as nutraceutical/food supplement. Hence phytosteryl ferulate is a potential substitute for natural oryzanol for several applications. | 12-26-2013 |
| 20150141678 | IONIZABLE CATIONIC LIPID FOR RNA DELIVERY - What is described is a compound of formula (1) | 05-21-2015 |
| 552545000 | Processes of isolating, purifying or recovering from animal, vegetable or fungal sources (e.g., wool fat or grease, lanolin, fish oils, animal tissue, soybean oil, tall oil or pitch, wood products, sugar cane, soap stocks, yeast, molds, etc.) | 6 |
| 20080207931 | Solid-Phase Extraction Method of Steroid Hormones by Entrapped Beta-Cyclodextrin Polymers - Provided is a method for selective extraction of steroid compounds using entrapped β-cyclodextrin polymers. Particularly, steroid hormones can be effectively selected from a biological sample by selectively extracting steroid compounds using entrapped β-cyclodextrin polymers, prepared by adding epichlorohydrin to β-cyclodextrin to prepare a polymer in a gel state, entrapping the polymer and pulverizing the products without using an additional device required in conventional solid-phase extraction. | 08-28-2008 |
| 20080262251 | Process For the Recovery of Sterols From Organic Material - A process for recovering sterols from organic material containing sterols and sterol derivatives. In a first step (a) the organic material is reacted with at least one of polyols, polyamines, alkanolamines or monohydric alcohols to increase the amount of free sterols in the organic material; (b) reacting residual reactants, and their esters or amides with epoxydated components; and (c) separating the free sterols from the mixture by short path distillation, thin film evaporation, or flash evaporation. The recovered sterols can be further purified by a crystallization step. | 10-23-2008 |
| 20090131697 | METHOD FOR THE PREPARATION OF PHYTOSTEROLS FROM TALL OIL PITCH - A method of preparing phytosterols from tall oil pitch containing steryl esters comprises the steps of converting the steryl esters to free phytosterols while in the pitch to produce a modified pitch containing the free phytosterols; removing light ends from the modified pitch by evaporation to produce a bottom fraction containing the free phytosterols; evaporating the bottom fraction to produce a light phase distillate containing the free phytosterols; dissolving the light phase distillate in a solvent comprising an alcohol to produce a solution containing the free phytosterols; cooling the solution to produce a slurry with the free phytosterols crystallized in the slurry; and, washing and filtering the slurry to isolate the crystallized phytosterols. | 05-21-2009 |
| 20100305342 | METHOD FOR THE PREPPARATION OF PHYTOSTEROLS FROM TALL OIL PITCH - A method of preparing phytosterols from tall oil pitch containing steryl esters comprises the steps of converting the steryl esters to free phytosterols while in the pitch to produce a modified pitch containing the free phytosterols; removing light ends from the modified pitch by evaporation to produce a bottom fraction containing the free phytosterols; evaporating the bottom fraction to produce a light phase distillate containing the free phytosterols; dissolving the light phase distillate in a solvent comprising an alcohol to produce a solution containing the free phytosterols; cooling the solution to produce a slurry with the free phytosterols crystallized in the slurry; and, washing and filtering the slurry to isolate the crystallized phytosterols. | 12-02-2010 |
| 20110098493 | Method of separating ergosterol - The present invention provides a method of separating ergosterol from a solution containing ergosterol in water-insoluble organic solvent, comprising supplying water to the solution and precipitating ergosterol. According to the method of the present invention, ergosterol crystals can be obtained at a high yield. Moreover, controlled water supply provides granular ergosterol aggregates exhibiting good solid-liquid separation character at a high yield. | 04-28-2011 |
| 20110207952 | CHOLESTEROL EXTRACTION FROM ALGAE AND PREPARATION OF VEGAN VITAMIN D3 - A process for producing vegan vitamin D3 from an algal waste processing stream by saponifying the waste stream to separate out and removing unsaponifiable cholesterol and converting it to vitamin D3 by ultraviolet irradiation, while precipitating out the saponified fatty acids, triglycerides and polysaccharides. | 08-25-2011 |
| 552546000 | Halogen or oxygen bonded directly to the acyclic carbon chain at the 17 beta-position (e.g., 25-hydroxy cholesterols, etc.) | 1 |
| 20080269512 | Large Scale Method for the deoxofluorination of ketones - A method for the deoxofluorination of a ketone for the production of a geminal difluoride compound in an industrial scale comprising the following steps:
| 10-30-2008 |
| 552547000 | Unsaturation between the 7- and 8-positions (e.g., ergosterols, 7 dehydrocholesterols, provitamin D, etc.) | 4 |
| 20100036140 | STEROLS MODIFIED BY POLYETHYLENE GLYCOL, THE PREPARATION AND THE USE THEREOF - The invention provides sterols modified by polyethylene glycol represented by the following formula, the preparation and the use thereof, wherein each symbol is defined as in the description. | 02-11-2010 |
| 20130144076 | WATER-SOLUBLE PHYTOSTEROL DERIVATIVES FOR REDUCING CHOLESTEROL AND PREPARATION THEREOF - Provided herein is a method of preparing a composition of a phytosterol derivative comprising a phytosterol intermediate coupled to a water-soluble carrier. The method controls the molecular structure of the product, resulting in phytosterol derivatives which are soluble in water at high concentration. The phytosterol derivatives provided herein are useful as ingredients for foods and pharmaceuticals, and have cholesterol-reducing effects. | 06-06-2013 |
| 20130317240 | Tailored Oils - Recombinant DNA techniques are used to produce oleaginous recombinant cells that produce triglyceride oils having desired fatty acid profiles and regiospecific or stereospecific profiles. Genes manipulated include those encoding stearoyl-ACP desturase, delta 12 fatty acid desaturase, acyl-ACP thioesterase, ketoacyl-ACP synthase, and lysophosphatidic acid acyltransferase. The oil produced can have enhanced oxidative or thermal stability, or can be useful as a frying oil, shortening, roll-in shortening, tempering fat, cocoa butter replacement, as a lubricant, or as a feedstock for various chemical processes. The fatty acid profile can be enriched in midchain profiles or the oil can be enriched in triglycerides of the saturated-unsaturated-saturated type. | 11-28-2013 |
| 20130331584 | Tailored Oils - Recombinant DNA techniques are used to produce oleaginous recombinant cells that produce triglyceride oils having desired fatty acid profiles and regiospecific or stereospecific profiles. Genes manipulated include those encoding stearoyl-ACP desturase, delta 12 fatty acid desaturase, acyl-ACP thioesterase, ketoacyl-ACP synthase, and lysophosphatidic acid acyltransferase. The oil produced can have enhanced oxidative or thermal stability, or can be useful as a frying oil, shortening, roll-in shortening, tempering fat, cocoa butter replacement, as a lubricant, or as a feedstock for various chemical processes. The fatty acid profile can be enriched in midchain profiles or the oil can be enriched in triglycerides of the saturated-unsaturated-saturated type. | 12-12-2013 |
