| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 552540000 |
Carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system is a member of an acyclic chain of six or more uninterrupted carbons (e.g., sterols, etc.)
| 23 |
| 552623000 |
Two oxygens bonded directly to the cyclopentanohydrophenanthrene ring system
| 15 |
| 552553000 |
Carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system is a member of an acyclic chain of three or four uninterruped carbons, (e.g., diketobisnorcholenic acids, etc.)
| 15 |
| 552557000 |
Carbon bonded directly at the 17-beta-position of the cyclopentanohydrophenanthrene ring system is a member of an acyclic chain of two uninterrupted carbons (e.g., pregnanes, etc.)
| 13 |
| 552610000 |
Acyclic carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system (e.g., etiocholanic acids, 17 cyanoetiocholanes, 17-aldehydrostanes, etc.)
| 9 |
| 552526000 |
Carbon double bonded directly to the cyclopentanohydrophenantrene ring system
| 9 |
| 552612000 |
Three or more oxygens bonded directly to the cyclopentanohydrophenanthrene ring system
| 8 |
| 552515000 |
Nitrogen bonded directly to the cyclopentanohydrophenanthrene ring system
| 6 |
| 552548000 |
Carbon bonded directly at the 17 beta-position of the cyclopentanohydrophenanthrene ring system is a member of an acyclic chain of five uninterrupted carbons (e.g., choladienes, cholanic acids, etc.) stocks, yeast, molds, etc.) | 5 |
| 20110087037 | SYNTHESIS OF RING B ABEO-STEROLS AS NOVEL INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS - Novel 3β-hydroxy-Δ | 04-14-2011 |
| 20160168189 | DEUTERATED BILE ACIDS | 06-16-2016 |
| 20100069654 | PROCESS FOR THE PREPARATION OF TAUROURSODESOXYCHOLIC ACID - The present invention relates to a novel method for preparing tauroursodeoxycholic acid which comprises a step of selective precipitation of the impurities present in the suspension obtained from the reaction of an aqueous solution of sodium taurinate with an acetonic solution of a mixed anhydride of ursodeoxycholic acid with an alkyl chloroformate. | 03-18-2010 |
| 20130267721 | PREPARATION OF BILE ACIDS AND INTERMEDIATES THEREOF - Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided. | 10-10-2013 |
| 20150141679 | METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID - Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxysteroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This inversion is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone. | 05-21-2015 |
| 552505000 |
Boron, silicon, selenium or tellurium containing | 5 |
| 20110046402 | NOVEL METHOD AND INTERMEDIATES FOR PREPARING 19-NORSTEROID COMPOUNDS - The subject of the invention is a method for preparing compounds of general formula (I): | 02-24-2011 |
| 20110082306 | BIRCH REDUCTION OF STEROID SUBSTRATES VIA ALKALI METAL - SILICA GEL MATERIALS - Steroids are well known, medicinal relevant, chemical entities. There are numerous steroids which have fully or partially reduced ‘A’ rings. These fully or partially reduced ‘A’ rings have been reduced in the past through Birch and other dissolving metal reductions. Novel reducing conditions for steroid substrates are described which utilizes stabilized alkali metal-silica gel materials. The invention relates to a method for reducing a double bond within a steroid by contacting an unsaturated steroid having a phenyl ring with a Stage 0 or Stage I alkali metal-silica gel material in the presence of a proton source under reaction conditions sufficient to form a reduced steroid having a diene structure. | 04-07-2011 |
| 20130123523 | METHODS FOR THE PREPARATION OF ETONOGESTREL AND DESOGESTREL - Described herein is a process for the synthesis of etonogestrel and desogestrel and intermediates used to form etonogestrel and desogestrel. | 05-16-2013 |
| 20140107358 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES - The present invention relates to a process for the preparation of a compound of formula (I) said process comprising the steps of: a) reacting a compound of formula (II), with an acylating or a silylating agent to produce a compound of formula (III), wherein P | 04-17-2014 |
| 20160122191 | Particle of Modified Silica - The present invention relates to a particle of modified silica which comprises a particle of silica which is covalently linked to at least one halohydrin moiety. Furthermore, the present invention relates to a method of preparing the particle of modified silica, a particle of modified silica obtained by such method, use of the particle of modified silica as a stationary phase for chromatography, as well as a separation column for chromatography comprising the particle of modified silica. | 05-05-2016 |
| 552506000 |
Phosphorus attached directly or indirectly to the cyclopentanohydrophenanthrene ring system by nonionic bonding | 4 |
| 20100240916 | PROCESS FOR OBTAINING STEROIDAL PHOSPHATE COMPOUNDS - A process for obtaining 21-disodium phosphate pregnane derivative compounds of formula (I), wherein X═R═H or X═F and R=α-CH | 09-23-2010 |
| 20130053586 | Novel Ecdysterone Synthesis Derivative, Preparation Method and Use Thereof - This invention discloses a novel compound with the structure of formula I, or pharmaceutically acceptable salts or solvates thereof. In addition, the invention further discloses a method for preparing the compound, a pharmaceutical composition containing the compound, and use thereof in the preparation of a hypoglycemic medicament. | 02-28-2013 |
| 20130066086 | NANOPARTICLE PEG MODIFICATION WITH H-PHOSPHONATES - The present invention provides phosphonate conjugates and methods of preparing the phosphonate conjugates so as to allow, for example, improved methods and compounds for modifying the surface of a nanoparticle to increase in vivo circulation times and targeted delivery performance. | 03-14-2013 |
| 20140323748 | WATER-SOLUBLE URSODEOXYCHOLIC ACID PRODRUGS - Ursodeoxycholic acid (UDCA) is a bile acid with demonstrated anti-apoptotic activity in both in vitro and in vivo models. Water-soluble prodrugs of UDCA for use in indications where intravenous administration of UDCA may be preferable, such as reducing damage from stroke or acute kidney injury, are disclosed. The disclosed prodrugs showed significant anti-apoptotic activity in a series of in vitro assays. | 10-30-2014 |
| 552510000 |
The cyclopentanohydrophenanthrene ring system is part of a polycyclo ring system having at least five cyclos | 4 |
| 20090076290 | SELECTIVE OXIDATION OF TRITERPENES EMPLOYING TEMPO - The present invention provides a process of preparing betulin-28-aldehyde from betulin. The process includes contacting betulin with a compound of formula (I), e.g., TEMPO (2,2,6,6-tetramethylpiperidine 1-oxyl) for a period of time effective to provide betulin-28-aldehyde. The present invention also provides a process of preparing betulinic acid. The process includes contacting betulin with a composition that includes: sodium hypochlorite (NaOCl); sodium chlorite (NaClO | 03-19-2009 |
| 20090318719 | METHOD OF PREPARATION AND ISOLATION OF BETULIN DIACETATE FROM BIRCH BARK FROM PAPER MILLS AND ITS OPTIONAL PROCESSING TO BETULIN - The invention relates to a method of preparation and isolation of betulin diacetate from birch bark from paper mills and its optional processing to betulin, wherein the birch bark is ground, mixed with two- to twenty-fold excess volume of water and is stirred so that all birch bark is dipped, then the fraction of the birch bark which floats on the surface is collected, said collected fraction is dried at the temperature in the range of from 50 to 85° C. and the betulin contained in the dried birch bark is then subjected to an acetylation reaction, after the acetylation the birch bark is dried at the temperature of from 50 to 100° C. and the formed betulin diacetate is then isolated from the birch bark by supercritical extraction of the birch bark with carbon dioxide at the pressure of 28-35 MPa and the temperature of from 50 to 100° C. and subsequently, the supercritical extract is recrystallized for direct use or for further processing. The further processing can be basic hydrolysis of the re-crystallized betulin diacetate to betulin. | 12-24-2009 |
| 20130137883 | Process for Production of Triterpene Alcohol - A process for producing triterpene alcohol, comprising sequentially conducting the following steps (A) to (C):
| 05-30-2013 |
| 20140296546 | METHOD FOR PRODUCING 30-HALOGENATED BETULINIC ACID - The invention discloses a method for producing 30-halogenated betulinic acid. Betulin is used as a raw material and selectively oxidized and halogenated to generate 30-betulinic acid, and the selected oxidation and halogenation agent has high selectivity and does not affect C-3 hydroxyl or carbon-carbon double bonds. Oxidation and halogenation are completed in one step, so the process route is short, the treatment method is simple, and the product is purified easily. | 10-02-2014 |
| 552536000 |
Halogen bonded directly at the 16-position of the cyclopentanohydrophenanthrene ring system | 1 |
| 20110137057 | Unsaturated Steroid Compounds - The invention relates to methods to manipulate stem cells in vivo and in vitro to treat, e.g., a condition where cell or tissue repair is needed. | 06-09-2011 |
| 552508000 |
Spiro | 1 |
| 20110144363 | PROCESS FOR OBTAINING 17-SPIROLACTONES IN STERIODS - The invention relates to processes for obtaining steroids with a spirolactone group in position 17, particularly to industrially obtaining 6β,7β; 15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone, commonly known as Drospirenone, as well as to intermediates useful in said process. | 06-16-2011 |
| 552504000 |
Heavy metal or aluminum containing | 1 |
| 20160152657 | Steroids as Agonists for FXR | 06-02-2016 |
| 552650000 |
Oxygen bonded directly at the 16- or 17-position of the cyclopentanohydrophenanthrene ring system | 1 |
| 20130331585 | CYCLOPROPYL PIDA BORONATE - Provided are protected cyclopropylboronic acids that include a substituted cyclopropyl group and a boronic ester group having a protecting group. The protecting group is a pinene-derived iminodiacetic acid (PIDA) group or PIDA-based group. | 12-12-2013 |
| Entries |
| Document | Title | Date |
|---|
| 20090221841 | 2-SUBSTITUTED ESTRA-1,3,5(10)-TRIENE-3-YL SULFAMATE WITH AN ANTI-TUMOUR ACTION - The invention relates to the use of 2-substituted estra-1,3,5(10)-triene-3-yl sulfamates of general formula I, in addition to their pharmaceutically acceptable salts for producing a medicament. Said compounds have an anti-tumour action. | 09-03-2009 |
| 20090253922 | Process for Production of Steroid Compound - The present invention relates to a process for production of a steroid compound having a partial structure represented by Formula (2) by oxidizing a steroid compound having a partial structure represented by Formula (1), without the need of any special apparatus, in a safe and economical manner, with less adverse affect on environment, in a simple and high efficient manner. Specifically, the invention relates to a process for producing a steroid compound having a partial structure of ring A and ring B of the steroid skeleton represented by Formula (2): | 10-08-2009 |
| 20110130580 | USE OF BUCKYSOME OR CARBON NANOTUBE FOR DRUG DELIVERY - Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the therapeutic agent is present in the vesicle interior or between layers of the vesicle wall, (ii) a substituted fullerene, comprising a fullerene core and a functional moiety, wherein the therapeutic agent is associated with the substituted fullerene, or (iii) carbon nanotubes, wherein the therapeutic agent is covalently bonded to the carbon nanotubes. | 06-02-2011 |
| 20130274489 | METHOD FOR OBTAINING PHYTOSTEROLS AND/OR TOCOPHEROLS FROM RESIDUE OF A DISTILLATION OF THE ESTERS OF VEGETABLE OILS, PREFERABLY FROM DISTILLATION RESIDUE FROM A TRANSESTERIFICATION OF VEGETABLE OILS - The invention relates to a method for obtaining and purifying phytosterols and/or tocopherols from distillation residue from a transesterification of vegetable oils, in particular from the vegetable oil-based fatty acid methyl ester production for the field of use of biodiesel (FAME), comprising a first transesterification stage for converting partial glycerides contained in the distillation residue; separating the glycerin phase from a reaction mixture resulting from the first transesterification stage; a second transesterification stage for converting sterol esters contained in the reaction mixture; adding water to the reaction mixture after the second transesterification stage in order to generate a multiphase system; simultaneously or sequentially separating the phases of the multiphase system into a substantially sterol-containing phase; a substantially glycerin- and methanol-containing aqueous phase; and a tocopherol-containing methyl ester phase; and obtaining phytosterols from the sterol-containing phase; and optionally obtaining tocopherols from the tocopherol-containing methyl ester phase. The invention further relates to a method for purifying a phytosterol phase and/or phytosterols. | 10-17-2013 |
| 20160060703 | HAPLOTYPE DETECTION - A method of diagnosing Ankylosing Spondylitis (AS), a spondyloarthropathy, arthritis, psoriasis, type-1 diabetes or a carcinoma comprising typing the ERAP1 haplotype of an individual. | 03-03-2016 |
