Class / Patent application number | Description | Number of patent applications / Date published |
536260200 |
Plural phosphorus atoms in N-glycoside
| 34 |
536260700 |
The N-hetero ring is part of a bicyclic ring system
| 29 |
536260800 |
The N-hereto ring is six-membered and monocyclic (e.g., uridine-5`-mono- phosphate, etc.)
| 21 |
536260800 |
The N-hereto ring is six-membered and monocyclic (e.g., uridine-5-mono- phosphate, etc.)
| 21 |
536260600 |
Labelled (e.g., tagged with radioactive tracer, fluorescent marker, intercalator, etc.)
| 8 |
536260110 |
The phosphorus is part of a ring | 5 |
20110028705 | METHOD FOR THE STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS COMPOUNDS - The present invention relates to a method for stereoselective synthesis of phosphorus compounds, whereby in the first reaction step a chiral auxiliary on the phosphorus atom of phosphoryl chloride, thiophosphoryl chloride or phosphorus trichloride is covalently bonded, the product from the first reaction step is reacted in the following step with an alcohol, thiol, or amine as the nucleophile in the presence of a base, and in the last step the chiral auxiliary is displaced from the product of the following step by a nucleophile. | 02-03-2011 |
20120116067 | METHOD FOR THE SOLID PHASE-BASED PRODUCTION OF PHOSPHATE-BRIDGED NUCLEOSIDE CONJUGATES - The invention relates to a method for producing phosphate-bridged nucleoside conjugates. In the method, a cyclosaligenyl nucleotide is produced first, to which a linker is added, which is used to perform the immobilization on a solid phase. A subsequent reaction with corresponding nucleophiles results in the desired phosphate-bridged nucleoside conjugates, which can then again be cleaved from the solid phase-bound linker. | 05-10-2012 |
20110288286 | PROCESS FOR THE ENZYMATIC PRODUCTION OF CYCLIC DIGUANOSINE MONOPHOSPHATE EMPLOYING A DIGUANYLATE CYCLASE COMPRISING A MUTATED RXXD MOTIF - A process is disclosed for the production of cyclic di-guanosine monophosphate (c-di-GMP) without the use of protecting groups by means of an enzymatic synthesis. The process comprises the coupling of two guanosine triphosphate (GTP) molecules so as to form a c-di-GMP molecule. This is done under the influence of a mutant diguanylate cyclase (DGC) comprising the amino acid sequence V153M154G155G156. It has been found that the DGC is obtainable from inclusion bodies, and therewith can be made available in amounts sufficient to improve the c-di-GMP synthesis. Particularly, the latter synthesis can be conducted in a one-pot method starting from commercially available bulk chemicals and allows upscaling to a commercial production scale. | 11-24-2011 |
20120316327 | SYNTHESIS OF PURINE NUCLEOSIDES - A process for preparing phosphoramidate prodrugs or cyclic phosphate prodrugs of nucleoside derivatives, which is a compound, its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof. | 12-13-2012 |
20130184450 | METHOD FOR PREPARING RIBONUCLEOSIDE PHOSPHOROTHIOATE - A method for preparing a phosphorothioate RNA based on the oxazaphospholidine method, wherein cyanoethoxymethyl group is used instead of tert-butyldimethylsilyl group as a protective group of 2′-hydroxyl group of RNA. | 07-18-2013 |
536260900 |
The N-hereto ring is five-membered (e.g., 1- -D-riboburanosyl-1, 2,3- triazole-4-carboxamide-5-phosphate, etc.) | 1 |
20100274000 | LIGHT-RESPONSIVE ARTIFICIAL NUCLEOTIDE HAVING PHOTO-CROSSLINKING ABILITY - The present invention provides a photoreactive crosslinking agent that is capable of crosslinking a sequence which cannot be photo-crosslinked by psoralen, and is capable of photo-crosslinking using a light having a longer wavelength, as compared with psoralen. The present invention also provides a compound having a group represented by formula (I) coupled with a group represented by formula (II). | 10-28-2010 |
20100274000 | LIGHT-RESPONSIVE ARTIFICIAL NUCLEOTIDE HAVING PHOTO-CROSSLINKING ABILITY - The present invention provides a photoreactive crosslinking agent that is capable of crosslinking a sequence which cannot be photo-crosslinked by psoralen, and is capable of photo-crosslinking using a light having a longer wavelength, as compared with psoralen. The present invention also provides a compound having a group represented by formula (I) coupled with a group represented by formula (II). | 10-28-2010 |
536260900 |
The N-hereto ring is five-membered (e.g., 1- -D-riboburanosyl-1, 2,3- triazole-4-carboxamide-5`-phosphate, etc.) | 1 |
20100274000 | LIGHT-RESPONSIVE ARTIFICIAL NUCLEOTIDE HAVING PHOTO-CROSSLINKING ABILITY - The present invention provides a photoreactive crosslinking agent that is capable of crosslinking a sequence which cannot be photo-crosslinked by psoralen, and is capable of photo-crosslinking using a light having a longer wavelength, as compared with psoralen. The present invention also provides a compound having a group represented by formula (I) coupled with a group represented by formula (II). | 10-28-2010 |
20100274000 | LIGHT-RESPONSIVE ARTIFICIAL NUCLEOTIDE HAVING PHOTO-CROSSLINKING ABILITY - The present invention provides a photoreactive crosslinking agent that is capable of crosslinking a sequence which cannot be photo-crosslinked by psoralen, and is capable of photo-crosslinking using a light having a longer wavelength, as compared with psoralen. The present invention also provides a compound having a group represented by formula (I) coupled with a group represented by formula (II). | 10-28-2010 |