Class / Patent application number | Description | Number of patent applications / Date published |
514772700 | Heterocyclic monomer | 34 |
20080262105 | 1-Vinylpyrrolidin-2-One/Ester Copolymers - The present invention refers to segment copolymers comprising segments “A” having polyvinylpyrrolidone (PVP) structure and segments “B” having a polyester | 10-23-2008 |
20090054535 | METHOD FOR EMBOLIZATION USING LIQUID EMBOLIC MATERIALS - A method for embolization using liquid embolic materials is described. The method comprises the use of two liquid components. The first liquid component is an aqueous solution or dispersion comprising at least one oxidized polysaccharide. The second liquid component is either an aqueous solution or dispersion comprising at least one water-dispersible, multi-arm amine, or a water-dispersible multi-arm amine in the form of a neat liquid. The two components crosslink in situ to form a hydrogel that should act as an effective embolic agent. | 02-26-2009 |
20090093550 | Biocompatible foams, systems, and methods - Biocompatible foams having excellent physical and chemical properties are described. The biocompatible foams can be formed in situ or applied as a pre-formed foam for the treatment of tissue. The invention provides biocompatible degradable foams formed with a poly-α(1→4)glucopyranose macromer. The invention also provides biostable foams formed with a poly(alkylene oxide) macromer. | 04-09-2009 |
20090318569 | METHOD FOR PRODUCING MICROSPHERES LOADED WITH DRUGS AND MICROSPHERES LOADED WITH DRUGS PRODUCED THEREBY - The present invention relates to a method for producing polymeric microspheres loaded with drugs and polymeric microspheres loaded with drugs produced thereby, specifically a method for producing polymeric microspheres loaded with drugs, the method comprising the steps of a) adding a dispersion phase containing a high molecular compound, a drug, and a water-insoluble organic solvent to a dispersion solvent to produce an O/W (oil-in-water) type or 0/0 (oil-in-oil) type emulsion, or adding a W/O (water-in-oil) type emulsion, which is prepared by emulsifying an aqueous solution, in which a drug is dissolved, in a water-insoluble organic solvent, in which the high molecular compound is dissolved, to the dispersion solvent to produce a W/O/W (water-in-oil-in-water) type emulsion; and b) adding an ammonia solution to the emulsion produced in step a) to convert the water-insoluble organic solvent into water-soluble solvents, and polymeric microspheres loaded with drugs produced thereby. According to the present invention, the desired polymeric microspheres loaded with drugs can be simply produced with a small amount of water in a short period of time. | 12-24-2009 |
20100010104 | Semi-Solid Delivery Vehicle and Pharmaceutical Compositions - A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed. | 01-14-2010 |
20100029788 | WET EDIBLE PEARLESCENT FILM COATINGS - Provided herein are wet powder compositions which include a pearlescent pigment, a film-forming edible polymer and from about 1% to about 30% by weight water. The wet powder compositions may be used to make pearlescent film coating suspensions which include a pearlescent pigment, a film-forming polymer, a plasticizer and from about 70% to about 95% water. The pearlescent film coating suspensions may be used to coat edible products, such as pharmaceuticals, confectionary products and food products. Also disclosed are methods of making the wet powder compositions and the pearlescent film coating suspensions. | 02-04-2010 |
20100048738 | HYBRID COMPOUNDS BASED ON POLYOL(S) AND AT LEAST ONE OTHER MOLECULAR ENTITY, POLYMERIC OR NON-POLYMERIC, IN PARTICULAR OF THE POLYORGANOSILOXANE TYPE, PROCESS FOR THE PREPARATION THEREOF, AND APPLICATIONS THEREOF - The invention relates to novel hybrid compounds comprising at least one polyon entity (Po)—for example oligomer or polymer—in which at least one of the hydroxyl functions of Po is substituted by at least one entity A that can be of a variable nature, for example polymer (e.g. polyorganosiloxane-POS), hydrocarbonated or mineral. The bond Ro between the entity Po and the entity A is obtained by means of “click chemistry” and corresponds to formula (II.1) or (II.2), Z representing —CH— or —N—. A is an entity selected from the group comprising the various polyols of Po, polyorganosiloxanes (POS), polyalkylene glycols, polyamides, polyesters, polystyrenes, alkyls, alkenyls, alkynyls, aryls, and combinations thereof, in addition to mineral materials such as silica and the combinations thereof. Said hybrid components can be used as emulsifiers, especially for cosmetics. | 02-25-2010 |
20100197807 | COMPOSITIONS COMPRISING REACTION PRODUCTS OF ALKYLAMIDOAMINES, ALKYLAMINOIMIDAZOLINES AND FREE AMINE AND THEIR USE - Compositions comprising reaction products of alkylamidoamines, alkylaminoimidazolines and free amine and also processes for their preparation and their use as solvents in agrochemical formulations. | 08-05-2010 |
20100317745 | Bioresorbable Polymers - A bioresorbable polymer is obtained by reacting together (a) a prepolymer comprising co-polymerised units of a caprolactone and poly(alkylene oxide) moieties; (b) a polycaprolactone diol comprising co-polymerised units of a caprolactone and a C | 12-16-2010 |
20110034567 | SEMI-CRYSTALLINE, FAST ABSORBING POLYMER FORMULATION - The present invention relates to a composition comprising a semi-crystalline, absorbable copolymer formulation wherein the first component is hydroxy-capped polycondensation product of diglycolic acid and a mixture of two idols, diethylene glycol (DEG) and ethylene glycol (EG), with DEG added in larger molar amount, and wherein the second component, glycolide is incorporated during the subsequent ring-opening polymerization. The resulting hydrophilic resin has low crystallinity level, glass transition temperature, Tg, slightly below room temperature, and may be particularly useful for making monofilaments, multifilaments, microspheres, or melt blown nonwoven constructs or other medical devices where fast hydrolysis rates and superior mechanical properties are desirable. | 02-10-2011 |
20110065809 | Polymerization of Multifunctional Azides, and Polymers Therefrom - Methods for preparing polymers from multifunctional azides and multifunctional azide-reactants are described in the present disclosure. Exemplary multifunctional azide-reactants include multifunctional alkynes and/or multifunctional α-phosphine esters. In certain embodiments, such polymers can be prepared in vivo. Such polymers can be useful in a wide variety of biomedical applications. | 03-17-2011 |
20110082219 | Thickeners - Disclosed are compounds obtained by reacting (a) epoxides (I) which comprise at least two epoxide groups per molecule, with (b) compounds of the structure (II), having substituents as defined, | 04-07-2011 |
20120004324 | Process for Preparing Cyclic Esters Comprising Unsaturated Functional Groups and Polyesters Prepared From Same - Disclosed herein are process for preparing cyclic esters comprising unsaturated functional groups. Also disclosed are copolymers prepared from the cyclic esters. The copolymers can be used to form microparticles, polymer micelles, etc., which are useful in drug delivery applications. | 01-05-2012 |
20120029090 | Modified alkoxylation products having at least one non-terminal alkoxysilyl group, with increased storage life and increased stretchability of the polymers prepared using them - Modified alkoxylation products of the formula (I), their use and processes for preparing them | 02-02-2012 |
20120071566 | Bioabsorbable Polymeric Compositions, Processing Methods, and Medical Devices Therefrom - Novel bioabsorbable polymeric blends are disclosed. The blends have a first component that is a polylactide polymers or a copolymer of lactide and glycolide and a second component that is poly(p-dioxanone) polymer. The novel polymeric blends provide medical devices having dimensional stability. Also disclosed are novel bioabsorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture. | 03-22-2012 |
20120077887 | TERPOLYMERS AS PRESSURE-SENSITIVE ADHESIVES - Disclosed herein are terpolymers that can function as pressure-sensitive adhesives. The disclosed articles comprise the terpolymers adhered to a release liner. The disclosed implant devices comprise the pressure-sensitive adhesive terpolymer adhered to a surface thereof. The pressure-sensitive adhesive terpolymer can promote adhesion of the implant device to a location in a subject. | 03-29-2012 |
20120088848 | METHODS AND COMPOSITIONS FOR CONTROLLED POLYPEPTIDE SYNTHESIS - Methods and compositions for the generation of polypeptides having varied material properties are disclosed herein. Methods include means for initiating the polymerization of aminoacid-N-carboxyanhydride (NCA) monomer by combining the monomer with an amido-containing metallacycle, for making self assembling amphiphilic block copolypeptides and related protocols for adding oligo(ethyleneglycol) functionalized aminoacid-N-carboxyanhydrides (NCAs) to polyaminoacid chains. Additional methods include means of adding an end group to the carboxy terminus of a polyaminoacid chain by reacting an alloc-protected amino acid amide with a transition metal-donor ligand complex to forming an amido-amidate metallacycle for use in further polymerization reactions. Novel compositions for use in peptide synthesis and design including five and six membered amido-containing metallacycles and block copolypeptides are also disclosed. | 04-12-2012 |
20120095113 | REFRESHING CREAM FOUNDATION IN GEL FORM - The present invention is directed to a cosmetic composition includes (a) at least one compound selected from a sugar silicone surfactant, a gelling agent, a polyamine and a hyperbranched polyol; and (b) at least one polar modified polymer. | 04-19-2012 |
20120136070 | KETAL ESTERS OF ANHYDROPENTITOLS AND USES THEREOF - The present disclosure relates to the preparation of ketal compounds from anhydropentitols and oxocarboxylates; derivatives, homopolymers, and copolymers thereof; and various compositions, formulations, and articles derived therefrom. | 05-31-2012 |
20120178827 | Solid Pharmaceutical Preparations Comprising Amphiphilic Copolymers On The Basis Of Polyethers In Combination With Surfactants - Dosage forms comprising formulations of sparingly water-soluble active ingredients in a polymer matrix composed of polyether copolymers, said polyether copolymers being obtained by free-radically initiated polymerization of a mixture of 30 to 80% by weight of N-vinyllactam, 10 to 50% by weight of vinyl acetate and 10 to 50% by weight of a polyether, and of at least one surfactant, in which the sparingly water-soluble active ingredient is present in amorphous form in the polymer matrix. | 07-12-2012 |
20120190756 | Dendritic Polyether-Polyurethane Thickeners - Described are associative polyether-polyurethane thickeners into which dendritic polyetherpolyols have been polymerized-in. Also described is the preparation of these thickeners, and the use thereof, in particular, in cosmetic preparations. | 07-26-2012 |
20130018111 | BIODEGRADABLE AND BIOCOMPATIBLE SHAPE MEMORY POLYMERS - This invention relates to shape memory block copolymers comprising: at least one switching segment having a T | 01-17-2013 |
20130123373 | Use Of Polyether-Based And Vinyl Monomer-Based Copolymers As Binders For Dosing Forms Comprising Solid Active Ingredients - The use of water-soluble or water-dispersible copolymers which are obtained by free radical-initiated polymerization of a mixture of
| 05-16-2013 |
20130317121 | METHOD FOR THE PREPARATION OF PLYMERS WITH VARIED ARCHTECTURE AND AMIDE INITIATION - The invention relates to a method for preparing linear polymers having an amide end or having a star architecture comprising an amide core, by means of a ring opening using lactide and glycolide monomers or a lactide monomer ring in the presence of a catalyst, wherein the method includes the steps of: (i) reacting the excess monomer(s) with an initiator in a solvent, said initiator being selected from among an amine and an amino alcohol, given that the initiator has at least one primary or secondary amine function; (ii) adding a catalyst, said catalyst being a non-nucleophilic base and including at least one neutral sp2 nitrogen atom; and (iii) neutralizing the reaction mixture. Said novel method is particularly advantageous in that it can be easily monitored and enables better modulation of the polymers, and thus of the properties thereof, than the methods of the prior art. The invention also relates to novel polymers that are obtainable by means of said method. | 11-28-2013 |
20130331464 | POLYLACTIDES COMPOSITIONS AND USES THEREOF - The present invention provides compositions and methods relating to polylactides which may be used for drug delivery (e.g., parenteral delivery), wherein an organic solvent is not required. | 12-12-2013 |
20140005278 | LINEAR POLYESTER AND SEMI-LINEAR GLYCIDOL POLYMER SYSTEMS: FORMULATION AND SYNTHESIS OF NOVEL MONOMERS AND MACROMOLECULAR STRUCTURES | 01-02-2014 |
20140066523 | Drug Delivery Compositions And Methods Of Use - The invention provides moldable drug delivery carriers made up of a suspension of a solid phase and an organic liquid phase for the sustained release of a therapeutic agent. The invention also provides multiphase drug delivery systems made up of a granular hydrophobic solid phase, an organic liquid phase and a hydrogel, for sustained drug delivery at varying rates over the life of the composition. | 03-06-2014 |
20140073705 | BIOABSORBABLE POLYMERIC COMPOSITIONS, PROCESSING METHODS, AND MEDICAL DEVICES THEREFROM - Novel bioabsorbable polymeric blends are disclosed. The blends have a first component that is a polylactide polymers or a copolymer of lactide and glycolide and a second component that is poly(p-dioxanone) polymer. The novel polymeric blends provide medical devices having dimensional stability. Also disclosed are novel bioabsorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture. | 03-13-2014 |
20140100292 | Use of moisture-conditioned disintegrants or expanding agents in tablet manufacture for the selective adjustment of the mechanical properties, the dissolving kinetics and/or the water loading of the tablets - The present invention relates inter alia to the use of moisture-conditioned disintegrants or expanding agents in tablet manufacture for the selective adjustment of the mechanical properties, the dissolution kinetics (dissolution) and/or the water loading of tablets. | 04-10-2014 |
20140179802 | FIBER COMPRISING A BIODEGRADABLE POLYMER - The present invention relates to a fiber comprising a biodegradable polymer which undergoes dimensional change upon injection in the human or animal body wherein the dimensional change is a reduction of the surface area to volume ratio of a factor 2 to 10. The fiber is sized for injection via a pharmaceutical syringe needle having a bore of at least 25 Gauge. The biodegradable polymer is an amorphous biodegradable polymer selected from the group of poly-hexamethylene carbonates or polyesteramides. The amorphous biodegradable polymer is a preferably a polyesteramide comprising alpha-amino acids, diols and dicarboxylic acids as building blocks. The invention further relates to the use of the fiber for the manufacturing of a medicament for the treatment of ophthalmic diseases. The invention also relates to a process for the manufacturing of the fiber comprising the following process steps; a. extruding a biodegradable polymer into a fiber fitting in a needle of at least 25 Gauge b. which while under tension is cooled below its glass transition temperature such that the resultant fiber is amorphous. | 06-26-2014 |
20140350127 | COLORANT COMPOUNDS DERIVED FROM GENIPIN OR GENIPIN CONTAINING MATERIALS - The present disclosure provides colorant compounds and methods of isolation of the colorant compounds derived from a reaction of genipin and an amine. The colorant compositions comprise purified compounds (e.g., a purified polymer or a purified dimer) obtained from multiple fractioning by chromatography of the reaction resulting material. The purified polymer or dimer can be used as a colorant by itself or in combination with another colorant for imparting color to a food, a drug, a cosmetic, a medical device, and textile products. | 11-27-2014 |
20150018431 | Lubricious Coating Compositions - In one aspect, the present disclosure pertains to lubricous coating compositions that comprise (a) a higher molecular weight polyvinylpyrrolidone, (b) a lower molecular weight polyvinylpyrrolidone, and (c) a polyfunctional unsaturated crosslinking agent. In some embodiments, such lubricous coating compositions are present in crosslinked form on the surface of a medical article. In some embodiments, the lubricous coating compositions further comprise a solvent, in which case such compositions may be, for example, applied to a substrate in the form of a layer and subsequently crosslinked, thereby forming a lubricious coating on the substrate. In another aspect, the present disclosure is directed to methods for forming various medical articles. | 01-15-2015 |
20150073060 | POLYLACTIDE COMPOSITIONS AND USES THEREOF - The present invention provides compositions and methods relating to polylactides which may be used for drug delivery (e.g., parenteral delivery), wherein an organic solvent is not required. | 03-12-2015 |
20160199536 | Photocrosslinkable Poly(Caprolactone Fumarate) | 07-14-2016 |