Entries |
Document | Title | Date |
20080200562 | Polymer Conjugate Enhanced Bioassays - Modified branched polymers are combined with bioactive agents which are one member of a binding pair for use in an assay. | 08-21-2008 |
20080207773 | Cosmetic, pharmaceutical and dermatological products - The invention provides cosmetic, pharmaceutical and dermatological compositions comprising at least one copolymer obtainable by free-radical copolymerization of
| 08-28-2008 |
20080227871 | Ampholytic Copolymer, Production Thereof, and Use of the Same - The following invention relates to copolymers containing silicone groups which comprise, in copolymerized form, at least one monomer with an ionogenic and/or ionic group and at least one crosslinking monomer, to a process for the preparation of such copolymers containing silicone groups by precipitation polymerization, and to the use of these copolymers. | 09-18-2008 |
20080227872 | Method for the preparation of 1-benzotriazolyl carbonate esters of poly (ethylene glycol) - The invention provides a method for preparing a 1-benzotriazolylcarbonate ester of a water-soluble and non-peptidic polymer by reacting a terminal hydroxyl group of a water-soluble and non-peptidic polymer with di(1-benzotriazolyl)carbonate in the presence of an amine base and an organic solvent. The polymer backbone can be poly(ethylene glycol). The 1-benzotriazolylcarbonate ester can then be reacted directly with a biologically active agent to form a biologically active polymer conjugate or reacted with an amino acid, such as lysine, to form an amino acid derivative. | 09-18-2008 |
20080262101 | Method to Prepare a Personal Care Composition From a Base Composition and a Method to Prepare the Base Composition - A base composition is provided which comprises water and a non-ionic surfactant mixture. The base composition is suitable for use in preparing a personal care product. | 10-23-2008 |
20080269354 | COMPOSITION CONTAINING AN OILY CONTINUOUS PHASE - Composition containing an oily continuous phase and a particulate phase, the oily continuous phase containing at least one dipentaerythritol ester, the particulate phase containing particles of acrylic polymer. Process for making up or caring for the skin, comprising the application of the invention composition to the skin. | 10-30-2008 |
20080280999 | Process for Making Pharmaceutical Compositions with a Transient Plasticizer - A process for making a solid oral dosage form that has a therapeutic compound (e.g., a poorly soluble and/or poorly compactible therapeutic compound) and a polymer. The process is accomplished by the use of an extruder. A transient plasticizer, e.g., a liquefied gas such as supercritical carbon dioxide, is added to facilitate processing of the materials. The transient plasticizer can serve to lower the viscosity of the mixture being processes and/or enhance the solubility of the therapeutic compound. | 11-13-2008 |
20080293827 | Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same - Disclosed is a block copolymer formed by coupling the following components with each other: (a) a copolymer (A) of a polyethylene glycol (PEG) type compound with a biodegradable polymer; and (b) at least one oligomer (B) selected from the group consisting of poly(β-amino ester) and poly(amido amine). A method for preparing the same block copolymer, and a polymeric hydrogel type drug composition comprising the temperature and pH-sensitive block copolymer and a physiologically active substance that can be encapsulated with the block copolymer are also disclosed. The multiblock copolymer is obtained by copolymerization of a pH-sensitive poly(β-amino ester) and/or poly(amido amine) type oligomer, a hydrophilic and temperature-sensitive polyethylene glycol type compound and a hydrophobic and biodegradable polymer. Therefore, the block copolymer can form a polymeric hydrogel structure due to its amphiphilicity resulting from the combination of a hydrophilic group and a hydrophobic group in the copolymer and ionization characteristics depending on pH variations, and thus can be used as a drug carrier for target-directed drug delivery depending on pH variations in the body. | 11-27-2008 |
20080293828 | Use of Copolymers as Solubilizers For Slightly Water-Soluble Compounds - The use of copolymers obtained by free-radical polymerization of a mixture of
| 11-27-2008 |
20080300321 | MULTICOLOR COMPONENT ADHESIVE SYSTEM - The present invention relates to a multicolor component adhesive system based on at least two miscible polymerizable components and a curative component, said system being suitable for providing an adhesive having any desired color. The present invention further relates to the use of the adhesive produced on the basis of the multicolor component adhesive system as an adhesive compound, jointing compound, repair material and/or filling material, preferably for plastics, more particularly cast stone, mineral substrates, more particularly natural stone, ceramic, earthenware, porcelain, metals and/or wood, and also to a method of producing the adhesive. | 12-04-2008 |
20080312343 | Novel Concentrated Inverse Latex, Process for Preparing It and Industrial Use Thereof - The invention relates to a composition in the form of a positive latex comprising a) between 50 wt. % and 80 wt. % of at least one cross-linked, branched, or linear organic polymer (P), b) between 5 wt. % and 10 wt. % of a water-in-oil (W/O) emulsifying system (S | 12-18-2008 |
20080312344 | DENDRIMERS MULTIVALENTLY SUBSTITUTED WITH ACTIVE GROUPS - The present invention relates to dendrimers being multivalently substituted with active groups, as well as to processes for the preparation thereof and to the use of such multivalent dendrimers. | 12-18-2008 |
20090012184 | Production of Dosage Forms Comprising a Solid Dispersion of a Microcrystalline Agent - A method is described for the production of dosage forms, which comprise a solid dispersion of a microcrystalline active substance, in which a thermoplastic polymer with a glass transition temperature Tg of at least 40° C. is melted and an active substance is dissolved homogeneously in the melt; crystallization of the active substance is initiated in the mass obtained; and the mass is cooled. Crystallization of the active substance can be initiated by adding a nonsolvent, seed crystals of the active substance or a derivatization reagent. In addition, crystallization can be initiated by holding the mass for a sufficient length of time at a temperature that is below the temperature at which the active substance is completely soluble in the mass. | 01-08-2009 |
20090018216 | POLYMER MICELLE COMPLEX INCLUDING NUCLEIC ACID - It is an object of the present invention to provide: a polyion complex that sufficiently retains a photosensitizing substance in serum and is excellent in terms of structural stability; a nucleic acid polyplex as a constituent thereof; and a device and a kit for delivering a nucleic acid into a cell. | 01-15-2009 |
20090023817 | Aqueous compositions comprising alkyl polyethylene glycol ether sulfates - The present invention provides aqueous compositions comprising, as well as water, 75% to 90% by weight of alkyl polyethylene glycol ether sulfates which are a mixture of compounds of formula (1) | 01-22-2009 |
20090048349 | COMPOSITIONS AND KITS FOR COMPOUNDING PHARMACEUTICALS - The invention provides compositions and methods for the convenient compounding of pharmaceuticals. Single and multiple unit of use kits are provided which contain all the necessary components required for preparing a compounded pharmaceutical. The kits of the invention include a first container having a first active agent and a second container having at least one second inactive agent. The kits of the invention are also useful for compounding veterinary pharmaceuticals. | 02-19-2009 |
20090048350 | GASTROINTESTINAL ABSORPTION ENHANCER MEDIATED BY PROTON-COUPLED TRANSPORTER AND ITS PREPARING METHOD - The present invention provides a pharmaceutical preparation that can improve absorption of a pharmaceutical compound in the gastrointestinal tract and that provides, through oral administration or like method, a blood concentration from which sufficient remedial effects can be expected, and a method for producing such a preparation. The invention is directed to a pharmaceutical preparation exhibiting excellent gastrointestinal absorbability comprising a compound recognized by a proton-coupled transporter and a pH-sensitive polymer in an amount sufficient for the gastrointestinal tract to acquire a pH at which the proton-coupled transporter optimally absorbs the compound into a cell. | 02-19-2009 |
20090069448 | Degradable polymer and process for production thereof - In one embodiment of the present invention, a degradable polymer having a peroxide bond therein is disclosed. The degradable polymer can be utilized in the fields of medicals or medical materials, can be applied to a DDS or gene delivery system, and can be used as a novel polymeric material or environmentally-friendly material. A polyperoxide, which is an alternating copolymer, has in a side chain thereof, a functional group (which is a substituent comprising a therapeutic molecule), a water-soluble substituent, or a biodegradable substituent. | 03-12-2009 |
20090076174 | CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS - The present invention relates to the discovery of biodegradable multi-armed oligomers wherein the end groups of these oligomers have been functionalized with biologically active molecules. The resultant multi-armed oligomers end-functionalized with biologically active molecules have a controllable degradation profile. The hydrolytic degradation of oligomers of the present invention releases the biologically active compound as such with no change in native chemical structure. | 03-19-2009 |
20090076175 | Polyamide-Polyether Block Copolymer - Copolymers having linked internal polyether blocks and internal polyamide blocks have advantageous physical properties and solvent-gelling abilities. The copolymer may be prepared from a reaction mixture that contains 1,4-cyclohexane dicarboxylic acid (CHDA) and poly(alkyleneoxy) diamine (PAODA). Optionally, the reaction mixture contains no monofunctional compound reactive with either amine or carboxylic acid groups, however some of this monofunctional compound may be present. Dimer diamine and/or dimer acid may be present in the reaction mixture. A copolymer may also be prepared from a reaction mixture containing dimer acid and at least two diamine compound(s) including PAODA and short-chain aliphatic diamine having 2-6 carbons (SDA), wherein: a) the reaction mixture comprises x grams of PAODA and y grams of SDA, and x/(x+y) is 0.8-0.98; b) the reaction mixture weighs z grams, and x/z is at least 0.25; and c) the reaction mixture contains either no co-diacid, or comprises a small amount of co-diacid, wherein, if the reaction mixture comprises a small amount of co-diacid, then acid equivalents from co-diacid contribute less than 25% of the total acid equivalents present in the reaction mixture. | 03-19-2009 |
20090088484 | NITRIC OXIDE (NO)-RELEASING POLYMERS AND COMPOUNDS AND USES THEREOF - The invention provides compositions that are NO-releasing polymers or low-molecular-weight NO-releasing compounds. The invention also provides the secondary amine polymers that are the precursors as well as the products of the NO-releasing polymers. The invention provides methods of making the secondary amine polymer precursors and the NO-releasing polymers. The invention provides methods for the nitrosation of low-molecular-weight amines and secondary amine polymers to form the corresponding low-molecular-weight NO-releasing compounds and polymers. | 04-02-2009 |
20090099267 | POLYMERS, COMPOSITIONS AND METHODS OF MAKING THE SAME - Polymers having a main chain having both aromatic units and aliphatic units (with repeating heteroatoms) and a side chain macromonomer are described. Methods of making these polymers using enzymatic synthesis and the applications of these polymers are also described. | 04-16-2009 |
20090105352 | FUNCTIONALIZED BIODEGRADABLE TRICLOSAN MONOMERS AND OLIGOMERS FOR CONTROLLED RELEASE - This invention relates to the discovery of functionalized triclosan monomers and oligomers that, when incorporated into a substrate of, or applied as part of a coating to, medical devices and/or consumer products may extend the duration of antimicrobial properties to the medical devices and/or consumer products. | 04-23-2009 |
20090105353 | COSMETIC OIL-IN-WATER EMULSION - A cosmetic or dermatological compositions of oil-in-water emulsion type, including, in a physiologically acceptable medium, at least gemini surfactant of formula (I): | 04-23-2009 |
20090143486 | CHARGE REVERSIBLE POLYMERS - Described are charge reversible polymers, peptides and their resulting colloidal particles, comprising polymers and peptides having primary and secondary amines that are protected as easily hydrolysable amides. The amides are charge-reversible such that at neutral pH they are negatively charged but become positively charged at pH less than 6 and thus are relatively stable at neutral pH but quickly hydrolyze at pH below 6. Incorporating a drug in a micelle or a polymer comprised of the charge-reversible polymers or peptides provides a drug carrier for delivering the drug preferentially to the solid tumor or other targeted cells. | 06-04-2009 |
20090149555 | METHOD FOR PREPARING POLYHYDROXYALKANOATES, POLYMERS THUS OBTAINED, COMPOSITIONS COMPRISING THEM AND THEIR USES - Method for preparing a polyhydroxyalkanoate (PHA) polymer by ring-opening polymerization of a lactone such as β-butyrolactone, that is preferably racemic, in which the polymerization is carried out in the presence of an initiator of formula (II): | 06-11-2009 |
20090209659 | Liquid Thickeners for Aqueous Systems - Liquid thickener for aqueous systems containing, as viscosity suppressing agent, from 5 to 40% wt of ethoxylated mono- and/or di-glycerides of carboxylic acids having from 6 to 18 carbon atoms, from 15 to 40% wt of a polyurethane associative thickener, obtained from the reaction of at least one organic polyisocyanate, at least one water soluble polyether diol and at least one hydrophobic capping agent containing from 10 to 24 carbon atoms, from 20 to 80% wt of water, and which is devoid of organic solvents, volatile organic compounds and other viscosity suppressing agents. | 08-20-2009 |
20090209660 | BIOMATERIAL CONTAINING DEGRADATION STABILIZED POLYMER - The present invention relates to a polymer based material comprising a water binding agent, whereas the water binding agent is present in an amount sufficient to chemically and/or physically absorb and/or adsorb water to prevent degradation of the polymer. It also relates to a polymer based material which comprises a plasticizer or organic solvent as well as a multi-component material or composite including materials encompassing a second polymer and/or an active agent. Furthermore it relates to a method for manufacturing the polymer comprising material and use of the material for the preparation of a pharmaceutical composition to be used for treatment of bone, cartilage and/or periodontal defects. The invention also encompasses a kit using the polymeric material. Further, the present invention encompasses the use of a water binding agent for inhibiting water induced degradation of a polymer comprising material, for inducing blood clot stabilization in a polymer comprising material and for increasing storage stability in a polymer comprising material, wherein the water binding agent is not removed prior to application of the material. | 08-20-2009 |
20090247649 | Compositions using evaporable silicone carriers for cosmetics, cleaning and care product compositions - This invention describes cosmetic, cleaning and care products compositions made using an evaporable siloxane liquid support or carrier having the molecular formula: | 10-01-2009 |
20090247650 | NOVEL CATIONIC ASSOCIATIVE POLYURETHANES AND THEIR USE AS THICKENERS - The invention relates to novel amphiphilic cationic associative polyurethanes of formula (I): | 10-01-2009 |
20090253805 | Photocurable Thiol-Ene Low Gas Permeability Membranes - The present invention provides modified multifunctional thiol-ene monomers wherein one or more thiols are reacted with a Michael addition reactive double bond compound. The present invention further discloses photocurable thiol-ene formulations comprising thiol-ene monomers including the modified multifunctional thiols. The present invention further discloses photocurable thiol-ene formulations comprising thiol-ene monomers and Michael addition reactive double bond molecules and a Michael catalyst. The formulations of the present invention can be photocured to make films or coatings. In a further disclosure, the formulations, including those comprised of unmodified multifunctional thiols and multifunctional enes, are photocured to form films applied to non-flexible or flexible polymer or non-polymer substrates suitable for food packaging, electronic products, optical products and other applications and free-standing films. The present invention further discloses photocurable thiol-ene formulations comprising thiol-ene monomers and Michael addition reactive double bond molecules and a Michael catalyst. These formulations are disclosed to form free-standing films and coatings on substrates when applied to flexible substrates. Such materials are suitable for use in the packaging of food products and other products which are to be maintained in a hermetically sealed relationship to the atmosphere. | 10-08-2009 |
20090253806 | POLYANHYDRIDE POLYMERS AND THEIR USES IN BIOMEDICAL DEVICES - A biocompatible, bioerodable polyanhydride polymer having a Young's modulus between about 1.5 and 3 and a selected rate of surface degradation, and methods of forming and using the polymer, are disclosed. The polymer is formed of a polyester prepolymer having a preferred molecular weight of greater than 5 and less than 7.5 Kdaltons, and a selected number of anhydride linkages between 5 and about 30. | 10-08-2009 |
20090275670 | DOG PHEROMONE FORMULATION AND DELIVERY SYSTEM - The present invention is directed to a dog behavioral control system comprising a low melting point polymer or copolymer, an unsaturated long chain fatty alcohol, and a dog-appeasing pheromone to produce a solid slow release generator of the pheromone. The system is useful for making animal collars and the like. | 11-05-2009 |
20090286886 | RESORBABLE POLYMER COMPOSITIONS FOR USE IN MEDICINE, DENTISTRY, AND SURGERY - We describe the medical, dental, and surgical uses of modified poly(alkylene) materials which are fully resorbable after implantation into the body, and compositions formulated with such modified poly(alkylene) materials. | 11-19-2009 |
20090292029 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF - Novel bioabsorbable and/or biocompatible polyurethanes, polyureas, polyamideurethanes and polyureaurethanes with tunable physical, mechanical properties and hydrolytic degradation profiles are provided for use in biomedical applications such as stents, stent coatings, scaffolds, foams, and films. The disclosed polymers may be derived from biocompatible and/or bioabsorbable polyisocyanates. The present invention also relates to new and improved methods for the preparation of the biocompatible and/or bioabsorbable polyisocyanates. | 11-26-2009 |
20090298953 | Drug delivery system and method of making the same - Disclosed is a method for making a composition which comprises of an array of unsaturated, aliphatic, biocompatible and biodegradable polyesters with photo curing capability which upon mixing with an active ingredient will provide an inject able liquid or putty-like material. The composition can be injected via a customary syringe and needle and be photocured in situ using visible light irradiation. Changing in the network crosslinking, molecular weight of the linear polymeric precursors and their chemical structures can control delivery rate of the active ingredient from the device. | 12-03-2009 |
20090326077 | POLYISOBUTYLENE URETHANE, UREA AND URETHANE/UREA COPOLYMERS AND MEDICAL DEVICES CONTAINING THE SAME - The present invention pertains to polyisobutylene urethane, urea and urethane/urea copolymers, to methods of making such copolymers and to medical devices that contain such polymers. According to certain aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment, an additional polymeric segment that is not a polyisobutylene segment, and a segment comprising a residue of a diisocyanate. According to other aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment and end groups that comprise alkyl-, alkenyl- or alkynyl-chain-containing end groups. | 12-31-2009 |
20100022662 | MODIFIED COMB COPOLYMERS - The present invention relates to modified comb copolymers comprising special structural units, which are produced by converting SMA resins and optionally special copolymers with an AB block copolymer structure with a mixture of at least one polyalkylene oxide monoamine and at least one amino alcohol, with a mixture of at least one polyalkylene oxide monoamine and at least one N,N-disubstituted diamine or a mixture of at least one polyalkylene oxide monoamine, at least one N,N-disubstituted diamine and at least one polymer selected from the group comprising monohydroxy-terminated polyalkylene oxides, monohydroxy-terminated polyesters and monohydroxy-terminated block copolymers comprising polyalkylene oxide and polyester blocks, and their monohydroxy-terminated side chains are converted to phosphoric acid ester groups or their N,N-disubstituted amino-terminated side chains are converted to quaternary ammonium salts, and their use as wetting and dispersing agents. | 01-28-2010 |
20100041770 | POLYMER-CERAMIC COMPOSITE AND METHOD - Methods and devices are shown for a composite material that is easily applied to a surface such as a bone defect in need of filling or reinforcement, etc. The composite material provides good mechanical properties such as compressive strength upon curing in the presence of water. Selected materials and methods as described are further bioabsorbable with absorption rates that are controllable to provide desired morphology over time. In selected embodiments a pharmaceutical agent further provides benefits such as bone growth, infection resistance, pain management, etc. | 02-18-2010 |
20100056646 | Hydroswellable, segmented, aliphatic polyurethane ureas and intra-articular devices therefrom - Hydroswellable, non-absorbable, biostable, segmented, aliphatic polyether-urethane-ureas or polyether-siloxane-urethane-ureas form a single component, intra-articular device for restoring joints with artificial cartilage, as a cartilage substitute for degenerated cartilage and/or for enhancing the remaining cartilage of an arthritic joint. The intra-articular devices can be bicomponent in nature comprising a biostable, articulating, non-absorbable component and an absorbable component in the form of a solid or microporous liner interfacing with the tissue of defective or diseased joint to support in situ tissue engineering. One or more bioactive agent with specific pharmacological function can be incorporated in the single or bicomponent intra-articular devices to supplement their structural functions. | 03-04-2010 |
20100063166 | Thickners - Disclosed are thickeners comprising at least one polyfunctional alcohol ester of formula (I), where G is a moiety which is obtained by removing all alcoholic hydroxyl groups from a polyhydric alcohol; A is an alkylene group having 2 to 4 carbon atoms, where all identical or different alkylene groups may be randomly distributed or present in blocks, n is a number from 101 to 200, and the total of m+p represents the total number of alcoholic hydroxy groups in the polyhydric alcohol, and RCO is an acyl moiety of saturated or unsaturated, linear or branched fatty acids having 6 to 22 carbon atoms. | 03-11-2010 |
20100099779 | Biocompatible material composition adaptable to diverse therapeutic indications - A kit for forming a biocompatible material provides a protein solution and a polymer solution including a derivative of a hydrophilic polymer with a functionality of at least three. Upon mixing. the protein solution and the polymer solution cross-link to form a non-liquid, three-dimensional network that degrades over time back to a liquid form. The polymer includes a degradation control region selected to achieve a desired degradation period and a cross-linking group selected to achieve a desired cross-linking period. The kit provides instructions for forming a mixture of the protein solution and polymer solution and for applying the mixture. The mixture serves as the foundation for multiple material composition species, each adapted to a specific therapeutic indication. | 04-22-2010 |
20100137453 | Polyurea Product as Thixotropic Rheology Modifying Agent - A thixotropic agent comprising a first polyurea reaction product of a first polyisocyanate with a first amine and a second polyurea reaction product of a second polyisocyanate with a second amine different from the first polyurea reaction product precipitated in the presence of the colloidal particles of the first reaction product. | 06-03-2010 |
20100137454 | Silicone Polymer Emulsions - Silicone oil-in-water emulsions containing a polysiloxane containing polymer is prepared by first preparing a polysiloxane containing polymer by the polymerisation of siloxane containing monomers and/or oligomers in the presence of an inert organopoly siloxane and/or an organic fluid, a suitable catalyst and optionally an end-blocking agent; and quenching the reaction if required. If required one or more surfactants may be introduced into the polysiloxane containing polymer to form a homogenous oil phase. Water is then added (in an amount of 0.1-10 percent by weight based on total oil phase weight) to the homogenous oil phase to form a water-in-oil emulsion. Shear is applied to the water-in-oil emulsion to cause inversion of the water-in-oil emulsion to an oil-in-water emulsion. Finally, if required the oil-in-water emulsion can be diluted by adding more water. | 06-03-2010 |
20100190871 | Gel Composition And Cosmetic - The present invention provides a gel composition having improved texture in use. A gel composition consisting of an organosiloxane derivative represented by the following formula (1) or (3), a monohydric aliphatic alcohol having 10 to 30 carbon atoms, and water. | 07-29-2010 |
20100240772 | PIGMENT-FREE, AQUEOUS POLYMER DISPERSIONS MARKED WITH FLUORESCENT DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE - Pigment-free, aqueous polymer dispersion marked with fluorescent dyes, having a viscosity of from 500 to 900 mPa·s, determined with the aid of the Brookfield method (spindle 3, 23° C.), and comprising, based in each case on the solids of the polymer dispersion,
| 09-23-2010 |
20100305217 | HIGH PERFORMANCE MEMBRANE - The invention relates to a micro-porous membrane comprising a porous membrane carrier made of a first polymeric material (A) and comprising a second polymeric material (B) intimately divided throughout the porous membrane carrier, wherein the porous membrane carrier comprises a plurality of interconnected polymeric fibers, fibrils, filaments and/or lamellae having a thickness of less than 1 μm, the porous membrane carrier has an interconnected open porous structure formed by the plurality of interconnected polymeric fibers, fibrils, filaments and/or lamellae and a porosity of at least 50%; and the polymeric material (B) comprises a thermoplastic polycondensation polymer and is present in an amount of at most 30 wt. %, relative to the total weight of (A) and (B). The invention also relates to a process for preparing such a micro-porous membrane comprising steps wherein (i) a porous membrane carrier made of a first polymeric material (A) is impregnated with a polymer solution comprising a second polymeric material (B) in a solvent system (X), and (ii) the resulting impregnated membrane carrier is quenched in a non-solvent system (Y), thereby precipitating at least part of the second polymeric material (B). | 12-02-2010 |
20110028570 | SELF EMULSIFYING GRANULES AND PROCESS FOR THE PREPARATION OF EMULSIONS THEREFROM - A process for making a self-emulsifying granule suitable for use in forming latex emulsions includes contacting a resin with a solid or highly concentrated surfactant, a solid neutralization agent and water in the absence of an organic solvent to form a mixture, melt mixing the mixture, and forming self-emulsifying granules of the melt mixed mixture. Self-emulsifying granules are also provided and configured to form a latex emulsion when added to water. | 02-03-2011 |
20110034566 | LONG TERM DRUG DELIVERY DEVICES WITH POLYURETHANE BASED POLYMERS AND THEIR MANUFACTURE - This invention is related to the use of polyurethane based polymer as a drug delivery device to deliver biologically active compounds at a constant rate for an extended period of time and methods of manufactures thereof. The device is very biocompatible and biostable, and is useful as an implant in patients (humans and animals) for the delivery of appropriate bioactive substances to tissues or organs. The drug delivery device for releasing one or more drugs at controlled rates for an extended period of time to produce local or systemic pharmacological effects comprises:
| 02-10-2011 |
20110046242 | Film Forming, Silicone Containing Compositions - The invention relates to silicone containing compositions able to form adhesive films on substrates, which typically comprises a curable silicone formulation containing: (a) a polyorganosiloxane polymer having at least two functional SiVi groups per molecule, each SiVi group containing an alkenyl functionality directly bonded to a silicon atom; (b) a crosslinker polyorganosiloxane compound having at least 3 Si-bonded hydrogen groups or SiH groups per molecule; (c) a chain extender compound which is a telechelic polyorganosiloxane having terminal SiH groups; (d) a hydrosilylation catalyst for the reaction of SiH groups with SiVi groups; (e) with RHV>1.5 wherein RHV is the ratio of the number of SiH moles in (b) and (c) to the number of SiVi moles in (a) and (d), and 002-24-2011 | |
20110065807 | PH SENSITIVE BIODEGRADABLE POLYMERIC PARTICLES FOR DRUG DELIVERY - The present invention generally relates to polymers and particles, such as nanoparticles. The particles and polymers generally include one or more buffering components. Additionally, the particles and polymers may include two or more components that impart useful properties (functionalities). The particles and polymers, for example, may include a buffering component and a degradable component. As described herein, the particles and polymers may also include a hydrophilic component and/or a cleavable bond component. The particles and polymers described herein have been found to be particularly effective when used for delivery of one or more agents, such as one or more pharmaceutical agents. Other aspects of the invention are directed to methods of using or administering such particles or polymers, kits involving such particles or polymers, and the like. The present invention also relates to particles containing a cleavable bond component and one or more fluorescence resonance energy transfer (FRET) pairs as well as methods of detecting the cleavage of the cleavable bond component of such particles. | 03-17-2011 |
20110065808 | CARBONYL COMPOUND REMOVER - A carbonyl compound remover comprising at least one polyether resin that includes a unit shown by any of the formulas (I) to (IV) as an active ingredient, a method of preventing coloration of an infusion comprising causing the carbonyl compound remover to come in contact with an infusion that may produce and accumulate a carbonyl compound during heat sterilization or storage, or an infusion that contains a carbonyl compound, and a novel crosslinked polyether resin are disclosed. The carbonyl compound remover that may suppress a Maillard reaction in a mixture of an amino acid infusion and a sugar infusion or the like to effectively prevent coloration due to a Maillard reaction, the method of preventing coloration of an infusion by using the remover, and the novel crosslinked polyether resin are offered in the present invention. In the formulas, n1 and n2 represent integers from 1 to 100, A represents a unit (A1) or (A2), or a combination of the (A1) and (A2), R represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, and Q represents a group shown by CH | 03-17-2011 |
20110098365 | SALT PRODUCT - A method of preparing a salt product comprises the steps of: (i) providing a mixture which comprises salt dissolved in a solvent, said mixture further containing an organic material that is solid under ambient temperature conditions; and (ii) atomising said mixture and evaporating said solvent to produce a salt product comprised of particles of salt incorporating said organic material. The organic material may be a polymer such as a carbohydrate (e.g. maltodextrin or Gum Arabic). Novel salt products are disclosed which comprise hollow particles having a shell formed for individual crystallites of salt. The salt product is useful as a seasoning for food and may be used in lower amounts than conventional salt to provide the same taste. Particular advantages are obtained in the baking of bread. | 04-28-2011 |
20110105627 | METHOD OF CONTROLLING OIL-ABSORBING PROPERTIES OF A SILICONE RUBBER POWDER - A method of controlling oil-absorbing properties of a silicone rubber powder characterized by keeping a silicone rubber powder in hot storage at a temperature in the range of 40° C. to 150° C. or in cold storage at a temperature in the range of 0° C. to 10° C. | 05-05-2011 |
20110105628 | WATER-DISPERSIBLE AND MULTICOMPONENT FIBERS FROM SULFOPOLYESTERS - Disclosed are multicomponent fibers derived from a blend of a sulfopolyester with a water non-dispersible polymer wherein the as-spun denier is less than about 6 and wherein the water dispersible sulfopolyester exhibits a melt viscosity of less than 12,000 poise measured at 240° C. at a strain rate of 1 rad/sec, and wherein the sulfopolyester comprising less than about 25 mole % of residues of at least one sulfomonomer, based on the total moles of diacid or diol residues. The multicomponent fiber is capable of being drawn at a relatively high fiber speed, particularly at least about 2000 m/min, and may be used to produce microdenier fibers. Fibrous articles may be produced from the multicomponent fibers and microdenier fibers. Also disclosed is a process for multicomponent fibers, nonwoven fabrics, and microdenier webs. | 05-05-2011 |
20110105629 | PROCESS AND SYSTEM FOR REDUCING SIZES OF EMULSION DROPLETS AND EMULSIONS HAVING REDUCED DROPLET SIZES - A method of producing an emulsion includes preparing a droplet solution comprising first and second molecular species, the droplet solution being in a fluid phase, wherein the first molecular species is soluble in the second molecular species; forming a plurality of droplets from the droplet solution in a bulk fluid to create a first emulsion, the plurality of droplets having a first ensemble average radius in the bulk fluid, wherein the first molecular species of the droplet solution is at least partially soluble in the bulk fluid and the droplet solution is at least partially immiscible in the bulk fluid; and allowing molecules of the first molecular species to migrate from the plurality of fluid droplets to the bulk fluid due to a higher concentration of the first molecular species in the droplet solution than the bulk fluid to result in the plurality of droplets having a second ensemble average radius that is smaller than the first ensemble average radius. An emulsion includes a bulk fluid and a plurality of droplets dispersed in the bulk fluid. The plurality of droplets have an ensemble average radius less than about 25 nm and greater than about 5 nm. | 05-05-2011 |
20110130471 | POLYURETHANES - Polyurethanes, suitable as thickeners for aqueous systems, are obtained by reacting (i) one or more hydrophilic polyols containing at least two OH groups and at least two functional groups selected from ether and ester groups, having a molecular weight of at least 300 Daltons; (ii) one or more C8 to C36 Guerbet alcohols, which are produced from monoalcohols having 4 to 18 carbon atoms selected from the group of primary and/or secondary monoalcohols of formula (MA), | 06-02-2011 |
20110144217 | POLYMER WITH SALT GROUPS AND ANTIFOULING COATING COMPOSITION COMPRISING SAID POLYMER - A film-forming polymer with improved chemical stability in antifouling coating applications, said polymer bearing pendant to its backbone a salt of (i) a basic group with a first pK | 06-16-2011 |
20110160310 | TCB BASED HYDROPHILIC POLYURETHANE DISPERSIONS - The present invention relates to a polyurethaneurea dispersion including a polyurethaneurea which is terminated with at least one polyethylene oxide- and polypropylene oxide-based copolymer unit, and includes a polycarbonate polyol-based unit of formula (I) | 06-30-2011 |
20110166240 | PH MODULATED FILMS FOR DELIVERY OF ACTIVES - The invention relates to pH modulated films and methods of their preparation. The film compositions include at least one component having a non-neutral pH when combined with water; and a pH modulated polymer system selected to reduce or prevent synerisis when combined with the non-neutral component in combination with aqueous media. The films demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, extrusion process, or other process that maintains the required uniformity of the film. | 07-07-2011 |
20110230567 | VINYL ALCOHOL CO-POLYMER CRYOGELS, VINYL ALCOHOL CO-POLYMERS, AND METHODS AND PRODUCTS THEREOF - A cryogel-forming vinyl alcohol co-polymer is operable to form a cryogel, i.e., a hydrogel formed by crytropic gelation, in an aqueous solution at a concentration of less than about 10% by weight, in the absence of a chemical cross-linking agent and in the absence of an emulsifier. In one embodiment, a vinyl alcohol co-polymer cryogel comprises at least about 75% by weight water and a vinyl alcohol co-polymer, wherein the vinyl alcohol co-polymer is operable to form a cryogel in an aqueous solution at a concentration of less than about 10% by weight, in the absence of a chemical cross-linking agent and in the absence of an emulsifier. In another embodiment, a vinyl alcohol co-polymer cryogel comprises at least abut 75% by weight water and a vinyl alcohol co-polymer comprising a saponified product of a vinyl acetate co- polymer formed from at least about 80% by weight of vinyl acetate monomer, and (i) at least about 3% by weight of acrylamide monomer or a mixture of acrylamide monomer and acrylic acid monomer, or (ii) at least about 5% by weight acrylic acid monomer. The vinyl acetate co- polymer, vinyl alcohol co-polymer and vinyl alcohol co-polymer cryogel may be formed according to particular methods, and the vinyl alcohol co-polymer cryogels may be used in various applications including biomedical implants and thin films and for delivery of therapeutic or cosmetic agents. | 09-22-2011 |
20110230568 | HEATING OF POLYMERS AND OTHER MATERIALS USING RADIATION FOR DRUG DELIVERY AND OTHER APPLICATIONS - The present invention generally relates to systems and methods for releasing a releasable species from an article using an external trigger, for example, using infrared or near-infrared radiation. Such systems and methods may be useful, for example in biological applications (e.g., as an implant within a subject), industrial applications, commercial applications, or the like. One aspect of the invention is generally directed to an article containing a radiation-sensitive polymer or other radiation-sensitive material. Exposure of the radiation-sensitive material to radiation such as infrared or near-infrared radiation may cause the material to increase in temperature. This increase in temperature may be used, in some cases, to cause the release of a drug or other releasable species from the article. For instance, a drug may be contained in a heat-sensitive material positioned in thermal communication with the radiation-sensitive material, or a drug may be contained within an enclosure that is isolated, at least in part, by a heat-sensitive material positioned in thermal communication with the radiation-sensitive material. In another aspect of the invention, a receive antenna may be used to focus infrared or near- infrared radiation on an article. For instance, the receive antenna may focus infrared or near-infrared radiation on a radiation-sensitive material in the article. Such focusing may be useful, in some embodiments, to control release of a drug or other releasable species from the article. Other aspects of the invention are directed to systems and methods of making or using such articles, e.g., by implanting the article within a subject, methods of treatment involving such articles, kits including such articles, and the like. | 09-22-2011 |
20110237687 | ADJUSTING DRUG LOADING IN POLYMERIC MATERIALS - Drug loading of polymeric materials can be adjusted by selection of materials and/or adjusting processing steps in formation of an implantable drug-loaded device. | 09-29-2011 |
20110245351 | MEDICAL ADHESIVE FOR SURGERY - The invention relates to novel rapidly-curing adhesives made from hydrophilic polyisocyanate prepolymers for application in surgery. | 10-06-2011 |
20110257273 | POLYESTER RESIN AND PURPOSES THEREOF - A low-molecular-weight polyester resin which can elasticize a resin suitably and can be used for various purposes, various resins obtained by using the resin, and the purposes thereof. The polyester resin is obtained by polymerizing a monomer composition containing 10 to 90 weight % of a linear dicarboxylic acid and/or diol having at least 8 carbon atoms (I), 5 to 80 weight % of a branched dicarboxylic acid and/or diol having at least 4 carbon atoms (II-1) and/or 2 to 40 weight % of at least one polyfunctional monomer (II-2) selected from the group consisting of polyols, polycarboxylic acids and hydroxycarboxylic acids having 3 or more functional groups respectively and which has the number average molecular weight of 500 to 5000 and is amorphous. | 10-20-2011 |
20110269848 | N-SUBSTITUTED MONOMERS AND POLYMERS - Biocompatible, bioresorbable polymers comprising a plurality of monomeric repeating units containing an amide group, wherein said amide groups are N-substituted and the N-substituent and degree of N-substitution are effective to lower the melt viscosity, the solution viscosity, or both, compared to the same polymer without N-substitution. | 11-03-2011 |
20110301247 | COSMETIC PRODUCT CONTAINING FILM-FORMING POLYMER - Disclosed herein is a cosmetic product which contains a polymer having the repeating unit represented by the following formula (1) or (2): | 12-08-2011 |
20110313053 | Thickeners Based on Polyurethane - Thickeners, which are based on an aqueous preparation of nonionic water-dispersible or water-soluble polyurethanes, it being possible to produce these polyurethanes by reacting
| 12-22-2011 |
20120004323 | IMPLANT PROCESSING METHODS FOR THERMALLY LABILE AND OTHER BIOACTIVE AGENTS AND IMPLANTS PREPARED FROM SAME - Disclosed herein are processes for preparing implants that are particularly useful for thermally labile bioactive agents but can also generally be used with any bioactive agent. The disclosed processes avoid the use of heat during processing and therefore avoid heat induced degradation of the bioactive agent. Also disclosed are implants prepared by the disclosed methods. | 01-05-2012 |
20120071564 | Emulsions Based On Hydroxyl Compounds Bearing Silyl Groups - The invention relates to emulsions containing hydroxyl compound bearing silyl groups, to the production and to the use thereof | 03-22-2012 |
20120083537 | TCD BASED HYDROPHILIC POLYURETHANE DISPERSIONS - The present invention relates to a polyurethaneurea solution having a polyurethaneurea having a structural unit of the formula (I) | 04-05-2012 |
20120088843 | POLYMERIZABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS - The invention provide a class of chain-extended polysiloxane crosslinkers which comprises (1) at least two polysiloxane segments, wherein each pair of adjacent polysiloxane segments is linked by one divalent organic radical which includes at least one pendant hydrophilic group (hydroxyl and/or carboxyl groups) or at least one dangling hydrophilic polymer chain and a di-thioether linkage —S-DR—S— in which DR is a divalent organic radical; and (2) two terminal ethylenically unsaturated groups. The present invention is also related to a polymer comprising crosslinking units derived from chain-extended polysiloxane crosslinker of the invention and to ophthalmic lenses comprising such a polymer. | 04-12-2012 |
20120088844 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS - The invention provide a class of linear chain-extended polysiloxane crosslinkers which comprises two terminal ethylenically unsaturated groups, at least two polysiloxane segments, and dangling hydrophilic polymer chains each covalently attached to a divalent organic radical separating each pair of adjacent polysiloxane segments. The present invention is also related to a polymer comprising crosslinking units derived from chain-extended polysiloxane crosslinker of the invention and to ophthalmic lenses comprising such a polymer. | 04-12-2012 |
20120095109 | Film Forming, Silicone Containing Compositions - The invention relates to silicone containing compositions able to form adhesive films on substrates, which typically comprises a curable silicone composition comprising components (a), (d) and at least one of (b) or (c): a. a polyorganosiloxane resin, composed of M and Q units having at least 3 alkenyl groups per molecule, herein after called “SiVi” groups, b. a poly-organosiloxane compound having at least 2 Si-bonded hydrogen groups on the polysiloxane chain, hereinafter called “SiH” groups, c. a telechelic polyorganosiloxane compound having terminal Si—H groups, and d. a hydrosilylation catalyst for the reaction of SiH groups with SiVi groups, e. a liquid diluent in an amount of from 0% to maximum 40% by weight of composition said components reacting together by hydrosilylation at a temperature below 400 C when they are brought into contact on a substrate and cure to form a continuous film on the substrate. Such formulation can cure quickly at room temperature and can provide good balance between adhesion and tack. | 04-19-2012 |
20120101170 | Polyurethane Thickeners - The present invention relates to a process for preparing polyurethanes, which comprise at least three hydrophilic sections, at least four hydrophobic sections, optionally allophanate segments and/or isocyanurate segments and which are prepared in the presence of alkali(ne earth) metal carboxylates. The process may comprise using at least one carboxylic acid salt of at least one metal selected from the group consisting of the alkali metals, the alkaline earth metals and mixtures thereof. Furthermore, the present invention relates to the polyurethanes per se obtainable in this way, to the use thereof as thickeners for aqueous preparations, and to preparations comprising polyurethanes of this type. | 04-26-2012 |
20120101171 | Polyurethane Thickeners - The present invention relates to a single-stage process for preparing polyurethanes which comprise at least three hydrophilic sections, at least four hydrophobic sections, optionally allophanate segments and optionally isocyanurate segments, in the presence of alkali(ne earth) metal carboxylates or zinc carboxylates. Furthermore, the present invention relates to the polyurethanes themselves obtainable in this way, to the use thereof as thickeners for aqueous preparations, and to aqueous preparations comprising polyurethanes of this type. | 04-26-2012 |
20120108677 | IMINIC MONOMERS AND POLYMERS THEREOF - Disclosed are biocompatible, bioresorbable polymers comprising a plurality of monomeric repeating units containing an imine group, wherein the inclusion of said imine group is effective to lower the melt viscosity, the solution viscosity, or both, compared to the same polymer without an imine group. | 05-03-2012 |
20120172455 | Functionalized water-soluble polyphosphazenes and uses thereof as modifiers of biological agents - A polyphosphazene polymer which includes hydrophilic side groups and interacting side groups which are capable of bonding with a biological agent of interest. The bonding may be by non-covalent bonding. | 07-05-2012 |
20120172456 | ENGINEERED MICROPARTICLES FOR MACROMOLECULE DELIVERY - A method for making a modified release composition, comprising:
| 07-05-2012 |
20120178825 | CYCLOHEXANEDIMETHANOL-BASED HYDROPHILIC POLYURETHANE UREA - The invention relates to novel polyurethane ureas which can be used in the production of hydrophilic coatings on various substrates. | 07-12-2012 |
20120202895 | PASTE COMPOSITION AND COSMETIC CONTAINING IT - The present invention has an object to provide a paste composition having a high thickening effect to an oil material such as a silicone oil and giving a silky and light feeling without poor spreading properties and without such feelings as an oily, a sticky, and an oil-film feeling and an object to provide a cosmetic containing it; wherein the paste composition comprises (I) an organopolysiloxane obtained by an addition polymerization of a polysiloxane mixture containing (i) one or more organohydrogen polysiloxane and (ii) one or more organopolysiloxane having an aliphatic unsaturated group and (II) at least one oil material that is a liquid at 25° C., selected from a silicone oil, a hydrocarbon oil, an ester oil, a natural plant and animal oil, and a semi-synthetic oil. | 08-09-2012 |
20120208895 | COMPOSITE MATERIAL WITH PROPERTIES OF SELF-HEALING AND RELEASE OF ACTIVE INGREDIENTS, FOR BIOMEDICAL APPLICATIONS - This invention relates to a composite material for biomedical applications, in particular dental applications, which possesses self-healing capacity and is able to incorporate a system for the release of active ingredients at the stage of application and use. | 08-16-2012 |
20120208896 | AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM - The present invention relates to the discovery of new class of hydrolysable amino acid derivatives and absorbable polyester amides, polyamides, polyepoxides, polyureas and polyurethanes prepared therefrom. The resultant absorbable polymers are useful for drug delivery, tissue engineering, tissue adhesives, adhesion prevention, bone wax formulations, medical device coatings, stents, stent coatings, highly porous foams, reticulated foams, wound care, cardiovascular applications, orthopedic devices, surface modifying agents and other implantable medical devices. In addition, these absorbable polymers should have a controlled degradation profile. | 08-16-2012 |
20120225952 | NON-AQUEOUS SILICONE-BASED OPHTHALMIC FORMULATIONS - Non-aqueous compositions including a silicone based excipient and methods of their use are provided. The non-aqueous compositions, products and methods of the present invention are particularly useful for the treatment of ophthalmic diseases | 09-06-2012 |
20120309852 | Polylactide Hydrosol and Articles Made Therefrom - A polylactide hydrosol polymer formulations suitable for thin film articles and methods of making the thin film articles are provided. The formulations and methods can be use to make articles such as gloves, condoms, catheters and the like using dip forming, and various casting processes. | 12-06-2012 |
20120322896 | NON-IONIC ASSOCIATIVE THICKENERS CONTAINING ALKYL CYCLOHEXYLOLS, FORMULATIONS CONTAINING THEM AND THEIR USES - New associative thickeners of the HEUR type (Hydrophobically modified Ethylene oxide URethane) whose hydrophobic monomer is based on alkyl cyclohexylols. These are new polyurethanes that allow a broad thickening of a medium shear gradient aqueous formulation while limiting the increase in the low shear gradient viscosity. The invention also concerns the compositions containing them and their uses in different formulations such as aqueous paints. | 12-20-2012 |
20120329883 | Polyurethane Elastomers - This disclosure relates to a linear polymer obtained by reacting a polyethylene glycol, a polypropylene glycol; a diol; and a diisocyanate, as well as a controlled release composition containing the linear polymer together with an active agent. The active agent can have a molecular weight of 200 g/mol to 20,000 g/mol. | 12-27-2012 |
20130005832 | SILKY-FEELING NON-AQUEOUS STRUCTURED COMPOSITION - Disclosed is a non-aqueous, structured, gel-form composition containing: (a) a low molecular mass N-acyl glutamic acid diamide having a straight-chain alkyl group; (b) a low molecular mass N-acyl glutamic acid diamide having a branched-chain alkyl group; (c) at least one gel-promoting solvent; (d) at least one silicone elastomer; (e) at least one solvent capable of solubilizing the silicone elastomer; and (f) at least one active ingredient, wherein the composition has a hardness value ranging from about 30 to about 300 gf, a melting point of about 500 C or higher, does not require use of wax as a structuring agent, and has a silky feeling when applied onto a keratinous substrate. Methods of making and using the compositions are also provided. | 01-03-2013 |
20130012596 | POLYMERIZATION OF ALKYL(BETA-N-ALKYLAMINOPROPIONATES) FORMING UNIQUE POLYAMIDE COMPOSITIONS - A process for preparing poly N-substituted beta-alanines with the steps of: | 01-10-2013 |
20130012597 | TEMPERATURE-, PH- OR SALT CONCENTRATION-SENSITIVE SEPARATION MATERIAL AND USE THEREOF - The present invention provides a UCST-type thermoresponsive polymer compound which responds to a temperature under physiological conditions and has biofunctionality, and various uses thereof as a thermoresponsive material. Specifically, the invention provides a thermoresponsive material containing, as an active ingredient, a polymer compound represented by Formula (I) below or an addition salt thereof, the thermoresponsive material having an upper critical solution temperature in the range of 5 to 50° C. in an aqueous solution with a salt concentration of at least 1 mM and a pH in the range of 3 to 10.5: | 01-10-2013 |
20130041042 | POLYMERIC COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR WOUND AND BURN TREATMENT AND OTHER USES - Polymeric compositions for enhanced wound or burn treatment characteristics and other medical, industrial, recreational and domestic applications can be formulated as biocompatible, elastomeric, polymers. Such compositions can be used as advanced wound or burn care dressings or for other medical and non-medical purposes. The compositions generally comprise a polymeric component including a polyurethane oligomer or polymer with one or more hydroxyl-containing acrylate or methacrylate terminal groups thereon, and an effective amount of a mercaptan (thiol) to regulate elastic and adhesive properties of the cured composition. During medical uses, the composition may be applied in a thin layer on the affected area and a generous portion of the adjacent healthy skin. The composition is then cured such as by exposure to an external energy source, for example a visible light or an ultraviolet light or infrared light or sunlight or a combination thereof, to form an elastomeric dressing. When the healing process is completed, the dressing can then be peeled off the skin. Articles of manufacture incorporating the polymeric compositions, which can be used in various products, are also provided. | 02-14-2013 |
20130085185 | CONTROLLED HYDROLYSIS OF POLY-4-HYDROXYBUTYRATE AND COPOLYMERS - Methods for making P4HB polymers and copolymers thereof that are useful for preparing controlled release systems, medical devices and as intermediates in chemical synthesis, have been developed. These methods avoid the use of organic solvents, and basic conditions that can cause transesterification reactions with polymer terminal end groups or elimination reactions. A preferred embodiment is a method for producing polymers of P4HB with weight average molecular weight less than 250,000, and more preferably, less than 100,000, and a Pd of less than 3, which are useful in controlled release. A particularly preferred embodiment utilizes aqueous acetic acid to hydrolyze pellets of P4HB polymers and copolymers while in suspension. | 04-04-2013 |
20130116341 | IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION - Provided herein are in vivo gelling pharmaceutical pre-formulations forming biocompatible hydrogel polymers that are polymerized in vivo and kits comprising at least one nucleophilic compound or monomer unit, at least one electrophilic compound or monomer unit, and optionally at least one therapeutic agent. The biocompatible hydrogel polymer is bioabsorbable and releases the therapeutic agent at a target site, avoiding systemic exposure. | 05-09-2013 |
20130131189 | ASSOCIATIVE NON-IONIC THICKENING AGENTS CONTAINING ALKYL CYCLOHEXANOL ALKOXYLATES, THEIR USES AND FORMULATIONS CONTAINING THEM - The present invention concerns new associative thickening agents belonging to the category of HEURs (Hydrophobically modified Ethylene oxide URethane). These products contain an original associative monomer with a base of alkyl cyclohexanol alkoxylates. Their thickening power is equal to or greater than that procured by HEUR associative thickening agents of the prior art containing grafted alkyl phenols. An efficient substitute product is therefore available, which is free of alkyl phenols, matching current market demand. | 05-23-2013 |
20130131190 | COMPOSITIONS COMPRISING POLYMERS PREPARED FROM 2-HYDROXYALKYL ACIDS - Described herein are compositions comprising polymers prepared by melt polycondensation of 2-hydroxyalkyl acids. Methods of making and using the compositions are also disclosed. | 05-23-2013 |
20130137780 | NON-ADHESIVE ELASTIC GELATIN MATRICES - The present invention is a substantially non-adhesive elastic gelatin matrix. The matrix is both non-adhesive to wounds, tissues and organs and is also elastic such that it is flexible. The matrix is a lyophilized mixture of protein(s), polymer(s), cross-linking agent(s) and optional plasticizer(s). The invention also provides methods for making the non-adhesive elastic gelatin matrix. | 05-30-2013 |
20130178538 | Long-Acting Injectable Analgesic Formulations for Animals - Long acting injectable analgesic formulations and methods for providing long lasting pain relief in animals are disclosed. | 07-11-2013 |
20130190408 | BIOCOMPATIBLE HYDROPHILIC COMPOSITIONS - Durable hydrophilic compositions comprising aliphatic polyester, an anionic surfactant, and in some embodiments, a carrier. | 07-25-2013 |
20130197099 | PARTIALLY ABSORBABLE FIBER-REINFORCED COMPOSITES FOR CONTROLLED DRUG DELIVERY - This invention describes a partially absorbable, fiber-reinforced composite in the form of a ring, or a suture-like thread, with modified terminals for use as a controlled delivery system of at least one bioactive agent, wherein said composite comprising an absorbable fiber construct capable of providing time-dependent mechanical properties of a biostable elastomeric matrix containing an absorbable microparticulate ion-exchanger to modulate the release of the bioactive agent(s) for a desired period(s) of time at a specific biological site; this can be a vaginal canal, peritoneal cavity, scrotum, prostate gland, an ear loop or subcutaneous tissue. Such drug delivery systems can be used for the local administration of at least one bioactive agent, including those used as contraceptive, antimicrobial, anti-inflammatory and/or antiviral agents as well as for cancer treatment. | 08-01-2013 |
20130203864 | Method of Production of Cosmetics Emulsion - The invention relates to the field of cosmetology and is referred to the technology for obtaining cosmetic skin care products. A method of manufacturing of cosmetic products includes gradual dispersion of components at room temperature at that the components are added to the plant with a powerful hydroacoustic effect, where dispersion of components and cavitation homogenization of emulsion with the further filling are made, at that the mode of acoustic cavitation is generated due to the double resonance effect in a flow channel. Mechanical oscillation of the rectangular flow channel system generates sound waves, forming of a standing wave at the fundamental frequency for the wall or walls of the flow channel. These standing waves in turn form a quasi-plane standing wave in a moving multi-phase media consisting of mixed ingredients. The method obtains superfine monodispersed cream emulsions with submicron size of the dispersed phase, resistant to coalescence, which significantly improve the organoleptic characteristics of cosmetic products, to allow reducing significantly the volume of ingredients required in the process of production of an emulsifier. | 08-08-2013 |
20130210931 | BIS-(ALPHA-AMINO)-DIOL-DIESTER-CONTAINING POLY (ESTER AMIDE) AND POLY (ESTER URETHANE) COMPOSITIONS AND METHODS OF USE - The present invention provides biodegradable, biocompatible bis-(α-amino acyl)-diol-diester-containing poly(ester amide) (PEA) and poly(ester urethane) (PEUR) co-polymer compositions with mechanical properties that can be readily tailored by selection of various combinations and proportions of the building blocks of the co-polymers. The compositions are suitable for use in production of drug-releasing biodegradable particles and implantable surgical devices, such as stents and internal fixation devices. The co-polymer compositions, particles and surgical devices biodegrade in vivo by enzymatic action to release bioactive agents in a controlled manner over time as well as biocompatible breakdown products, including one to multiple different amino acids. | 08-15-2013 |
20130217790 | Compositions Comprising Bioadhesives And Methods Of Making The Same - In one aspect, compositions are described herein. In some embodiments, a composition comprises a polymer or oligomer formed from one or more polycarboxylic acids, one or more alcohols, and one or more catechol-containing species. In another aspect, methods of making a composition are described herein. In some embodiments, a method of making a composition comprises providing a polycarboxylic acid; providing an alcohol; combining the polycarboxylic acid with the alcohol; adding a catechol-containing species to the combination of the polycarboxylic acid and the alcohol; and forming a polymer or oligomer from the polycarboxylic acid, the alcohol, and the catechol-containing species. In some embodiments, the catechol-containing species comprises an amine moiety, a carboxylic acid moiety, or a hydroxyl moiety that is not part of the catechol group. | 08-22-2013 |
20130225698 | COSMETIC PREPARATION CONTAINING CROSSLINKABLE SILICONE RUBBER EMULSION AND ITS PRODUCTION METHOD - A cosmetic preparation containing a crosslinkable silicone rubber emulsion comprising (A) 100 parts by weight of a straight chain or branched organopolysiloxane containing at least two hydroxyl groups bonded to the silicon atom per molecule prepared by ring-opening polymerization of a cyclic organosiloxane in the presence of an alkoxysilane or its partial hydrolytic condensate or an α,ω-dihydroxy or dialkoxy siloxane oligomer by using a catalyst selected from citric, lactic, and ascorbic acids and an anionic surfactant emulsifier; and (B) 0.5 to 20 parts by weight of a reaction product of an amino group-containing organoxysilane and an acid anhydride. | 08-29-2013 |
20130231400 | Copolymers Containing Phosphorylcholine Groups and Methods of Preparing and Using the Same - Methods for synthesizing a random copolymer having a phosphorylcholine group. Syntheses involving a reaction mixture containing a chain transfer agent (CTA), a solvent, a hydrophobic methacrylate monomer, a 2-methacryloyloxyethyl phosphorylcholine (MPC) monomer, and, optionally, an initiator. The random copolymers produced by such synthesis methods having a polydispersity index (PDI) of less than about 1.3 and a peak molecular weight (M | 09-05-2013 |
20130245134 | Degradable Therapeutic Delivery Device - A biodegradable biodelivery device is disclosed. The biodelivery device is formed from a polymer comprising the reaction product of a polyol and a polyacid. When exposed to water, the polymer degrades through hydrolysis. Of particular advantage, the polymer can be formed so as to be elastic and flexible. In one embodiment, the polymer is formed into a vaginal insert. As the polymer degrades, the polymer releases acid to a vaginal environment for decreasing the pH of the environment. | 09-19-2013 |
20130253073 | PHOTOCATALYST COMPOSITION AND PREPARATION FOR THE SAME - A solid solution photocatalyst composition and its preparation method are provided in the present invention. The solid solution photocatalyst can utilize its solid solution structure to regulate the conduction band position, valence band position, conduction band range and valence band range of the different response properties of the photocatalyst, so that oxidoreductive reaction is performed to remove the foul-smelling substances. | 09-26-2013 |
20130261194 | Functionalized Water-Soluble Polyphosphazenes and Uses Thereof as Modifiers of Biological Agents - A polyphosphazene polymer which includes hydrophilic side groups and interacting side groups which are capable of bonding with a biological agent of interest. The bonding may be by non-covalent bonding. | 10-03-2013 |
20130267611 | COSMETIC COMPOSITION COMPRISING A SUPRAMOLECULAR COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS, A SILICONE OIL AND A WAX - The present invention relates to a solid cosmetic composition comprising, in a cosmetically acceptable medium, (i) a supramolecular compound that may be obtained by reaction between:—at least one oil bearing at least one nucleophilic reactive function chosen from OH and NH | 10-10-2013 |
20130289136 | SACCHARIDE POLYMER OBTAINED FROM MANIHOT ESCULENTA, PRODUCTION PROCESS, AND USE AS COSMETIC ACTIVE INGREDIENT FOR TIGHTENING THE SKIN - A glucan biopolymer obtained from | 10-31-2013 |
20130310465 | WATER-SOLUBLE POLYALKYLENE OXIDE-MODIFIED PRODUCT - The present invention provides a water-soluble polyalkylene oxide-modified product which is nonionic, has a high thickening effect and is also excellent in transparency, and an emulsion composition and a cosmetic material containing the same. More specifically, the present invention provides a water-soluble polyalkylene oxide-modified product obtained by reacting a monovalent hydrophobic alcohol, a linear diol compound, a polyalkylene oxide compound and a diisocyanate compound, and an emulsion composition and a cosmetic material containing the same. | 11-21-2013 |
20130317119 | Poly-Alpha-Olefin -Containing Cosmetic Composition - The invention is directed to a cosmetic composition which contains at least one poly-α-olefin produced by subjecting at least one primary alcohol to dehydrating polymerization at a temperature of 60° C. to 340° C. in the presence of acidic alumino layer silicates. The primary alcohol is an alcohol from the group of unsaturated monofunctional alcohols, branched monofunctional alcohols and difunctional alcohols. The poly-α-olefin is a high-spreading oil component which imparts an almost instantaneous and relatively long-lasting feeling of smoothness to the skin and has good dermatological compatibility. | 11-28-2013 |
20130317120 | FUNCTIONALIZED NON-PHENOLIC AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM - The present invention relates to compound of formula I, which are functionalized, non-phenolic amino acids, and polymers formed from the same. | 11-28-2013 |
20130338239 | Bi-Modal Emulsions - Bi-modal water continuous emulsions are disclosed comprising at least 70 weight percent of: a first dispersed phase containing a hydrophobic oil, wherein the hydrophobic oil is provided as a non-emulsified hydrophobic oil, a second dispersed phase containing a silicone, wherein the silicone is provided from a water continuous silicone emulsion containing at least one surfactant. | 12-19-2013 |
20140031436 | Polylactide Hydrosol and Articles Made Therefrom - A polylactide hydrosol polymer formulations suitable for thin film articles and methods of making the thin film articles are provided. The formulations and methods can be use to make articles such as gloves, condoms, catheters and the like using dip forming, and various casting processes. | 01-30-2014 |
20140051770 | INJECTABLE MULTIMODAL POLYMER DEPOT COMPOSITIONS AND USES THEREOF - Injectable depot compositions are provided that include a polymer matrix having a plurality of bioerodible, biocompatible polymers wherein each polymer of the plurality of polymers has a specified weight average molecular weight; and the polymer matrix has a broad molecular weight distribution of the plurality of polymers; a solvent having a miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith; and a beneficial agent. The compositions are have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection. | 02-20-2014 |
20140073704 | COLLAGEN SCAFFOLDS, MEDICAL IMPLANTS WITH SAME AND METHODS OF USE - The subject invention concerns non-degradable three dimensional porous collagen scaffolds and coatings. These scaffolds can be prepared around sensors for implantation into a body. A specific embodiment of the invention concerns implantable glucose sensors. Sensors comprising a collagen scaffold of the invention have improved biocompatibility by minimizing tissue reactions while stimulating angiogenesis. The subject invention also concerns methods for preparing collagen scaffolds of the invention. The subject invention also concerns sensors that have a collagen scaffold of the invention around the exterior of the sensor. | 03-13-2014 |
20140080921 | BIODISINTEGRABLE MEDICAL DEVICES - According to an aspect of the present invention, the present invention provides medical devices which contain one or more polymeric regions that are at least partially biodisintegrable in bodily fluid. These devices may be implanted or inserted into a subject for treatment of various diseases, disorders and conditions. | 03-20-2014 |
20140128478 | PUNCTAL PLUG COMPRISING A WATER-INSOLUBLE POLYMERIC MATRIX - Disclosed is a pharmaceutical composition comprising a water insoluble polymer matrix that comprises a bioerodable polyester polymer or a fatty acid based polyester polymer, or a mixture of both polymers, wherein the polymer matrix has a melting point of less than 60° C., and wherein the composition is liquid or paste at room temperature and is formulated to occlude a punctual channel in a subject and conforms to the shape of the canalicular or punctal channel. | 05-08-2014 |
20140135406 | WATER-IN-SILICONE OIL MACROEMULSION COSMETIC COMPOSITION - A water-in-silicone oil (W/S) macroemulsion cosmetic composition of waterdrop quick break type is provided. The silicone oil phase part (S) contains a partly crosslinked emulsifiable silicone elastomer, a partly crosslinked non-emulsifiable silicone elastomer, and silicone oil, and the aqueous phase part (W) contains 1,3-butylene glycol and a lower alcohol, and also, at least one member selected from the group consisting of organic acid salts, inorganic salts, and polyhydric alcohols excluding glycerin and 1,3-butylene glycol as a freeze stabilizer at a predetermined composition. The cosmetic composition instantaneously releases water upon application on the skin. The cosmetic composition is stable at the extremely low temperature of −20° C., and it retains its dispersion stability even after repeated freezing and thawing, and accordingly, it can be used in a variety of cosmetic product. | 05-15-2014 |
20140135407 | BIODEGRADABLE NANOCOMPOSITES WITH ENHANCED MECHANICAL PROPERTIES FOR SOFT TISSUE ENGINEERING - The present invention is directed to a novel poly(diol citrates)-based nanocomposite materials created using completely biodegradable and biocompatible polymers that may be used in tissue engineering. More specifically, the specification describes methods and compositions for making and using nanocomposites comprised of citric acid copolymers and polymers including but not limited to poly(L-lactic acid) (PLLA) and poly(lactic-co-glycolic acid) (PLGA). | 05-15-2014 |
20140142199 | ABSORBABLE BRANCHED POLYESTERS AND POLYURETHANES - The present invention relates to the discovery of a new class of hydrolysable isocyanates, hydrolysable branched polyols and branched absorbable polyesters and polyurethanes prepared therefrom. The resultant absorbable polymers are useful for drug delivery, stents, highly porous foam, reticulated foam, tissue engineering, tissue adhesives, adhesion prevention, bone wax formulations, medical device coatings, surface modifying agents and other implantable medical devices. In addition, these absorbable polymers can have a controlled hydrolytic degradation profile. | 05-22-2014 |
20140148514 | POLY(ALKYLENE CO-ADIPATE TEREPHTHALATE) PREPARED FROM RECYCLED POLYETHYLENE TEREPHTHALATE HAVING LOW IMPURITY LEVELS - This disclosure relates to an aliphatic-aromatic copolyester of poly(butylene-co-adipate terephthalate) that is prepared from recycled polyethylene terephthalate in the presence of titanium catalyst and a phosphorous containing compound. The copolyester is contaminated with little or no ethylene glycol and/or isophthalic acid, which are artifacts of preparing the copolyester from recycled PET. Advantageously, because there is little or no contamination from ethylene glycol and/or isophthalic acid in the copolyester, there is essentially no depression in the material's melting temperature. | 05-29-2014 |
20140194533 | BIOCOMPATIBLE AND BIODEGRADABLE ELASTOMER - The present invention provides a biocompatible and biodegradable elastomer, comprising a hard segment and a soft segment. The hard segment is formed by reacting diisocyanate and a chain extender; and the soft segment is comprising a biodegradable oligomer diol, wherein the biodegradable oligomer diol is selected from the group consisting of polycaprolactone diol, polyethylene butylene adipate diol (PEBA diol), poly-L-lactic acid diol (PLLA diol), polylactic acid diol and any combination thereof. The biocompatible and biodegradable elastomer of present invention can be used to produce vascular graft, cell carrier, drug carrier or gene carrier. | 07-10-2014 |
20140243426 | COMPOSITION FOR CRYOPRESERVATION OF CELLS AND TISSUES - A composition for cryopreservation of cells and tissues of human and other animals in a safe manner without using toxic substances such as DMSO, as well as for freeze preserving or freeze-drying of foods and pharmaceuticals. In embodiments, ε-poly-L-lysine is reacted with succinic anhydride so that 60% or more of amino groups are blocked; and, thus obtained polymer compound is added to Dulbecco-modified eagle MEM culture medium (DMEM) on market sale to form a cryopreservation liquid. In embodiments for foods or pharmaceuticals, the ε-poly-L-lysine derivative was added by 0.5-10 wt % to curb freeze concentration. | 08-28-2014 |
20140243427 | Process for Preparing a Synthetic Foam Having a Controlled Particle Distribution - The invention relates to processes for preparing a synthetic foam having present therein particles with a controlled particle distribution and the use of said foam, as well as to foams as such. Accordingly the invention is directed to a process for preparing a synthetic foam having present therein particles, wherein the distribution of said particles is controlled by the following steps of dissolving at least one synthetic polymer in one or more solvents to form a solution; contacting particles with said solution to form a polymer/particles mixture; and freeze-drying the polymer/particles mixture by: freezing the polymer/particles mixture; and subsequently subliming the one or more solvents to form a synthetic foam comprising said particles. | 08-28-2014 |
20140288190 | HYDROGELS WITH BIODEGRADABLE CROSSLINKING - Hydrogels that degrade under appropriate conditions of pH and temperature by virtue of crosslinking compounds that cleave through an elimination reaction are described. The hydrogels may be used for delivery of various agents, such as pharmaceuticals. This invention provides hydrogels that degrade to smaller, soluble components in a non-enzymatic process upon exposure to physiological conditions and to methods to prepare them. The hydrogels are prepared from crosslinking agents that undergo elimination reactions under physiological conditions, thus cleaving the crosslinking agent from the backbone of the hydrogel. The invention also relates to the crosslinking agents themselves and intermediates in forming the hydro gels of the invention. The biodegradable hydro gels prepared according to the methods of the invention may be of use in diverse fields, including biomedical engineering, absorbent materials, and as carriers for drug delivery. | 09-25-2014 |
20140316012 | In-Situ Forming Foams for Embolizing or Occluding a Cavity - The present invention provides systems and methods for occluding and/or embolizing a cavity within a patient by delivering a prepolymer material into or onto a cavity and forming an expanding foam within the cavity. The inventions methods are applicable to occluding a variety of cavities, including blood vessels, aneurysms, left arterial appendages, vascular malformations and the like. | 10-23-2014 |
20140336277 | Radiopaque iodinated and iodide-containing crystalline absorbable aliphatic polymeric materials and applications thereof - Radiopaque, iodinated, absorbable polyesters, polyester urethanes, and polyether-ester-urethanes with and without inorganic iodide micro-/nanoparticles dispersed or solubilized therein, and composite inorganic iodide micro-/nanoparticles in an absorbable polyester, polyester-urethane, polyester-ester, or polyether-ester urethane matrix are employed in medical devices and therapeutic compositions. | 11-13-2014 |
20140357729 | TOPICAL COMPOSITION CONTAINING SILICONE BASE - It is an object to provide a topical composition that is excellent in texture and feeling upon use. The present invention is a topical composition without water, satisfying the following: (A) the composition includes a silicone base in a proportion of 80% by weight or more; (B) the silicone base includes (b1) a silicone elastomer, (b2) a cyclic volatile methylsiloxane having 3 to 6 silicon atoms, and (b3) a linear dimethylpolysiloxane and/or linear methylphenylpolysiloxane; (C) the composition includes therein an active ingredient present in a dispersed or dissolved type; and (D) the composition does not contain any non-silicone thickener. | 12-04-2014 |
20140357730 | NON-TEXTILE POLYMER COMPOSITIONS AND METHODS - Included are polymer compositions such as polyurethaneureas, polyamides and polyesters. The compositions may be in a variety of forms such as dispersions, powders, fibers, and beads. The compositions are useful in the preparation of many products including health and beauty products such as cosmetics, paint, household products such as fabric care compositions, apparel/footwear and textiles/furnishings. | 12-04-2014 |
20140378553 | METHOD FOR PRODUCING ORGANOPOLYSILOXANE EMULSION COMPOSITION - A method for producing an organopolysiloxane emulsion composition, which enables the organopolysiloxane to be formed with a high viscosity in a short period of time, and suppresses the amount of octamethylcyclotetrasiloxane (D4) to not more than 3,000 ppm. Specifically, a method for producing an organopolysiloxane emulsion which includes emulsifying a mixture containing an organopolysiloxane represented by formula: HO(R | 12-25-2014 |
20150057368 | CLOSED CELL FOAMS INCLUDING POLY-4-HYDROXYBUTYRATE AND COPOLYMERS THEREOF - Methods to produce substantially closed cell foams with densities less than 0.75 g/cm | 02-26-2015 |
20150126615 | COMPOSITIONS AND DEVICES OF POLY-4-HYDROXYBUTYRATE - Compositions of P4HB with high purity have been developed. The compositions are prepared by washing P4HB biomass prior to solvent extraction, and precipitating P4HB from solution. The same solvent is preferably used to wash the P4HB biomass, and as a non-solvent to precipitate the polymer from a P4HB solvent solution. The highly pure P4HB compositions are suitable for preparing implants. The implants may be used for the repair of soft and hard tissues. | 05-07-2015 |
20150291797 | BI-MODAL EMULSIONS - Bi-modal water continuous emulsions are disclosed comprising at least 70 weight percent of a first dispersed phase containing a hydrophobic oil, wherein the hydrophobic oil is provided as a non-emulsified hydrophobic oil, a second dispersed phase containing a silicone, wherein the silicone is provided from a water continuous silicone emulsion containing at least one surfactant. | 10-15-2015 |
20150299375 | URETHANE-TYPE POLYMERS AND USE THEREOF - The present invention is a urethane-type polymer obtained by a reaction of:
| 10-22-2015 |
20150305990 | OIL-IN-WATER FORM ORGANOGEL COSMETIC COMPOSITION HAVING VARIABLE TRANSPARENCY - There is provided an oil-in-water type organogel cosmetic composition having variable transparency, including 0.05% by weight to 50.00% by weight of an oil phase portion, and 50% by weight to 99.95% by weight of a water phase portion on the basis of total weight, wherein the oil phase portion and the water phase portion has a difference in refractive indices within a range of 0.03 to 0.16. The organogel cosmetic composition may be usefully utilized because the composition not only has high formulation stability according to temperature and time, but also enables an optimal application time to be easily determined with the naked eye by controlling the contents of components contained in the water phase portion and the oil phase portion in such a manner that the color of the composition may be changed from opaque ivory white color to transparent color when the composition is applied to skin. | 10-29-2015 |
20150361224 | AMINO-SUBSTITUTED POLYSILOXANES COMBINED WITH POLYMERIZABLE AND UNPOLYMERIZABLE ORGANIC ACIDS - Provided is a composition comprising (i) a polysiloxane comprising a plurality of pendant amines and (ii) an acid. Also provided is a composition comprising (i) a polysiloxane comprising a plurality of pendant acids and (ii) an amine. The compositions are useful inter alia for chemical or oil spill cleanup, drug delivery systems, transparent films, adhesives, binding agents, conductors, membranes, cross-linking agents, or opticoelectronic applications. Also provided are methods for making the compositions of the invention, as well as a battery and a composition for controlled release of a compound, each comprising a composition of the invention. | 12-17-2015 |
20150366781 | COSMETIC PREPARATION CONTAINING CROSSLINKABLE SILICONE RUBBER EMULSION AND ITS PRODUCTION METHOD - A cosmetic preparation containing a crosslinkable silicone rubber emulsion comprising (A) 100 parts by weight of a straight chain or branched organopolysiloxane containing at least two hydroxyl groups bonded to the silicon atom per molecule prepared by ring-opening polymerization of a cyclic organosiloxane in the presence of an alkoxysilane or its partial hydrolytic condensate or an α,ω-dihydroxy or dialkoxy siloxane oligomer by using a catalyst selected from citric, lactic, and ascorbic acids and an anionic surfactant emulsifier; and (B) 0.5 to 20 parts by weight of a reaction product of an amino group-containing organoxysilane and an acid anhydride. | 12-24-2015 |
20160023997 | ABSORBABLE POLYURETHANES AND METHODS OF USE THEREOF - Disclosed are novel bioabsorbable and biodegradable monomer compounds, bioabsorbable and biodegradable polymers therefrom, and methods of making such monomers and polymers, which are useful in pharmaceutical delivery systems, tissue engineering applications, tissue adhesives products, implantable medical devices, foams and reticulated foams for wound healing and drug delivery, bone hemostats and bone void fillers, adhesion prevention barriers, meshes, filters, stents, medical device coatings, pharmaceutical drug formulations, consumer product and cosmetic and pharmaceutical packaging, apparel, infusion devices, blood collection tubes and devices, other medical tubes, skin care products, and transdermal drug delivery materials. | 01-28-2016 |
20160045643 | Method for Making Biodegradable Anti-Adhesion Membranes for Cardiac Surgery - A method for the manufacture of biodegradable membranes for preventing adhesion formation followed open heart surgery is described herein. The manufacturing of biodegradable membranes is based on polymeric composition, comprised of copolymer of polyhydroxybutyrate/hydroxyvalerate (PHBV), poly(D,L-lactide) in the ratio of the dried powders of 3:1, the resulting mixture is dissolved in chloroform to a concentration of 6-9% followed by thorough mixing for 2 hours and heating up to 35° C. The membrane is produced by electrostatic spinning (electrospinning), wherein biologically active substances from fibrinolytic agents or direct anticoagulants are embedded in the structure of the fiber. | 02-18-2016 |
20160081304 | PET CHEW TOY ASSEMBLY - A pet chew toy assembly including a first component, wherein the first component includes a thermoplastic, a binding agent, and bone meal, and an optional second component, wherein the second component includes at least one of a natural rubber, a synthetic rubber, a thermoplastic rubber, a thermoplastic elastomer, and combinations thereof. | 03-24-2016 |
20160095297 | Pet Chew Toy Assembly - A pet chew toy assembly including a body having a first component, wherein the first component comprises a thermoplastic, a bone meal, and an antler powder. | 04-07-2016 |
20160102176 | FIBER COMPRISING A BIODEGRADABLE POLYMER - The present invention relates to a fiber comprising a biodegradable polymer which undergoes dimensional change upon injection in the human or animal body wherein the dimensional change is a reduction of the surface area to volume ratio of a factor 2 to 10. The fiber is sized for injection via a pharmaceutical syringe needle having a bore of at least 25 Gauge. The biodegradable polymer is an amorphous biodegradable polymer selected from the group of poly-hex am ethylene carbonates or polyesteramides. The amorphous biodegradable polymer is a preferably a polyesteramide comprising alpha-amino acids, diols and dicarboxylic acids as building blocks. The invention further relates to the use of the fiber for the manufacturing of a medicament for the treatment of ophthalmic diseases. The invention also relates to a process for the manufacturing of the fiber comprising the following process steps; a. extruding a biodegradable polymer into a fiber fitting in a needle of at least 25 Gauge b. which while under tension is cooled below its glass transition temperature such that the resultant fiber is amorphous. | 04-14-2016 |
20160120985 | MOLECULAR ASSEMBLY USING AMPHIPATHIC BLOCK POLYMER, AND SUBSTANCE-CONVEYANCE CARRIER USING SAME - Provided is a molecular assembly having any nano-sized particle diameter depending on its intended use and application, in various fields such as pharmaceutical drugs, agricultural chemicals, cosmetics, food products, and electronics. Furthermore, provided is a nano-carrier for delivering various substances using the molecular assembly having any nano-sized particle diameter. A molecular assembly comprising: an amphiphilic block polymer A1 comprising a hydrophilic block having a sarcosine unit and a hydrophobic block having a lactic acid unit; and an amorphous hydrophobic polymer A2 having an aliphatic hydroxy acid unit, wherein a number of aliphatic hydroxy acid units contained in the amorphous hydrophobic polymer A2 exceeds twice a number of lactic acid units contained in the hydrophobic block of the amphiphilic block polymer A1. | 05-05-2016 |
20160122468 | Esters Of Oligo-Hydroxycarboxylic Acids And Use Thereof - Esters of oligo-hydroxycarboxylic acids have the general formula ( ): | 05-05-2016 |
20160136083 | Personal Care Products That Do Not Contain Tetramer And/or Pentamer Cyclomethicones - The invention provides personal care products that do not contain D4 and/or D5 cyclomethicones but which do have the skin feel, spreadability, and other physical and chemical characteristics of personal care products that do contain these cyclomethicones. The products of the invention include a neopentyl polyol polyester(s) derived from neopentyl glycol, an isoparaffin(s), and a personal care formulation. Also included are replacement compositions for use in personal care products (so that D4 and D5 cyclomethicones can be excluded from the formulation) and methods of preparing personal care products and replacement compositions. | 05-19-2016 |
20160166739 | BIOERODIBLE POLYMER COMPOSITIONS | 06-16-2016 |
20160175479 | COMPOSITE MATERIAL FOR TISSUE REPAIR | 06-23-2016 |
20160177095 | MIXTURES OF POLYDIORGANOSILOXANE POLYAMIDE-CONTAINING COMPONENTS AND ORGANIC POLYMERS | 06-23-2016 |
20160194446 | HYDROXYPOLYAMIDE GEL FORMING AGENTS | 07-07-2016 |