Entries |
Document | Title | Date |
20080269193 | Tetrahydroindole and Tetrahydroindazole Derivatives - The invention provides indole and indazole compounds of Formula (I) | 10-30-2008 |
20090181944 | METHOD FOR CANCER THERAPY - The present invention provides a method for treating a patient having cancer comprising administering to the patient a therapeutically effective amount of compound (1), or a pharmaceutically acceptable salt thereof, having the formula: | 07-16-2009 |
20090286771 | 2-Phenoxy- and 2-Phenylsulfonamide Derivatives with CCR3 Antagonistic Activity for the Treatment of Inflammatory or Immunological Disorders - Provided herein are 2-phenoxy- and 2-phenylsulfonamide derivatives with CCR3 antagonistic activity. These compounds are useful for the treatment of diseases associated with CCR3 activity, including but not limited to, atopic dermatitis, allergic rhinitis, rheumatoid arthritis, Grave's disease, HIV infection, Alzheimer's disease, atherosclerosis and other inflammatory and/or immunological disorders. | 11-19-2009 |
20100009965 | CYCLIC MALONAMIDES AS INHIBITORS OF ABETA PROTEIN PRODUCTION - This invention relates to novel cyclic malonamides having the formula (I): | 01-14-2010 |
20100016286 | Anti-Inflammatory Agents - The invention provides compounds, pharmaceutical compositions and uses of compounds and salts thereof of general formula (I), for the preparation of a medicament for treatment of an inflammatory disorder, but excluding (S)-3-(r-methylcyclohexyl-carbonylamino)-caprolactam: wherein z is 1, 2, 3 or 4; A is —CO— or —SO2-; Q is linear or branched alkyl, alkenyl, alkynyl, alkoxy, oxyalkyl, aminoalkyl, alkylamino, alkylaminoalkyl, haloalkyl, aryl or substituted aryl; T | 01-21-2010 |
20100197660 | AZEPINE DERIVATIVES AS GAMMA-SECRETASE INHIBITORS - Compounds of formula (I), pharmaceutical compositions comprising them, and methods for their use are described. | 08-05-2010 |
20100204204 | NUTRACEUTICAL CO-CRYSTAL COMPOSITIONS - Co-crystals comprising at least one nutraceutical compound and at least one co-crystal former with or without impurities. These co-crystals may be included in compositions (optionally also including other components such as pharmaceutically acceptable excipients, other nutritional supplements, etc.) having utility as pharmaceuticals, nutraceuticals, nutritional supplements, and foodstuffs. | 08-12-2010 |
20100292213 | Anti-Inflammatory Agents - The invention provides compounds, compositions and uses of compounds of general formula (I) or pharmaceutically acceptable salts thereof, which are 3-aminocaprolactam derivatives, for the preparation of a medicament intended to treat an inflammatory disorder: | 11-18-2010 |
20110003792 | ANTI-INFLAMMATORY AGENTS - The invention provides compounds, pharmaceutical compositions and uses of compounds and salts thereof of general formula (I), for the preparation of a medicament for treatment of an inflammatory disorder, | 01-06-2011 |
20120077803 | Uses Of NK Receptor Antagonists - The invention provides the use of a compound of formula (I) | 03-29-2012 |
20130172319 | Alpha-AminoCycloLactam Ligands for G-Protein Coupled Receptors, and Methods of Using Same - The invention relates to the generation of a library of compounds enriched in agonist and antagonists for members of the G-protein coupled class of receptors (GPCRs). | 07-04-2013 |
20130203734 | ANTI-INFLAMMATORY AGENTS - Disclosed herein are methods of preventing or treating inflammatory diseases using sulfonamide analogs of 3-aminolactam compounds, each with aromatic “tail groups”. Compounds as defined by formulae (I) and (I′), and the medical uses of the compounds, are described herein. | 08-08-2013 |
20140005175 | Substituted Aromatic Sulfur Compounds and Methods of Their Use | 01-02-2014 |
20140005176 | 2-Phenoxy- and 2-Phenylsulfonamide Derivatives with CCR3 Antagonistic Activity for the Treatment of Inflammatory or Immunological Disorders | 01-02-2014 |
20140024639 | Compounds, Compositions, and Methods for Cancer Therapy - Compounds including various oligomers of piperlongumine and/or piperlongumine analogues as well as certain piperlongumine analogues that exhibit improved toxicity to cancer cells are disclosed. Also provided are compositions that comprise the compounds, methods of making compositions comprising the compounds, methods of making the compounds, and the use of compounds in methods for treating cancer. | 01-23-2014 |