| Entries |
| Document | Title | Date |
|---|
| 20080206884 | Sensor System with Actuated Structure Releasing a Coloured Indicator - The invention relates to a sensor system for detecting a target substance, and for providing visual indication of a presence of the target substance. The sensor system comprising at least a first fluid system, and a second fluid system containing a coloured or colour inducing indicator substance. The sensor system further comprises a flexible structure separating the at least first fluid system and the second fluid system, the flexible structure having a surface being functionalized to interact with a target substance in a fluid present in the first fluid system. The flexible structure upon exposure to the target substance releases energy stored in the flexible structure resulting in a mechanical actuation of the flexible structure, resulting in a release of the coloured substance either into the first fluid system or into a third fluid system connected to the second fluid system, or resulting in a colouring of a substance released either into the first fluid system or into a third fluid system connected to the second fluid system. | 08-28-2008 |
| 20080220535 | PHOTOELECTROCATALYTIC FLUID ANALYTE SENSORS AND METHODS OF FABRICATING AND USING SAME - Fluid analyte sensors include a photoelectrocatalytic element that is configured to be exposed to the fluid, if present, and to respond to photoelectrocatalysis of at least one analyte in the fluid that occurs in response to impingement of optical radiation upon the photoelectrocatalytic element. A semiconductor light emitting source is also provided that is configured to impinge the optical radiation upon the photoelectrocatalytic element. Related solid state devices and sensing methods are also described. | 09-11-2008 |
| 20080227215 | Method and arrangement of measuring acidity for other chemical or physical property of a gas - A method and an arrangement of measuring acidity or other chemical or physical property of a gas. The invention comprises a membrane having optical indicator molecules bound to a microporous matrix arranged to be placed into contact with the gas to be measured, the optical indicator molecules changing their colour in response to the acidity or other chemical or physical property of the gas, a light source, and a detector. The light source is arranged to emit and direct light to the membrane, the light being transmitted through the membrane, whereby a part of the light is absorbed into the optical indicator molecules, and the rest of the light emitted is guided to the detector, where it is measured. | 09-18-2008 |
| 20080241951 | METHOD AND APPARATUS FOR MOVING STAGE DETECTION OF SINGLE MOLECULAR EVENTS - An apparatus and method based on the apparatus is disclosed for detecting and monitoring chemical and/or bio-chemical reactions or interactions at the single molecule level, where detection and monitoring is improved by moving the viewing field of the detector in a controlled manner. The motion of the moving frame is accomplished either through software in the detector system or is accomplished by moving the reacting system. The motion is controlled and is either linear, circular or elliptical. The motion provides for improved site identification or mapping, improved event detection and monitoring, improved signal recognition and improved noise reduction. | 10-02-2008 |
| 20080241952 | Sensor with Holographic Multiplexed Image Display - A holographic sensor comprising a thin film polymer matrix that undergoes a change in response to a substance to be sensed, the matrix containing within its volume a set of two or more holographic recordings, each recording providing a holographic image when the sensor is illuminated, wherein the presence or appearance of each image is visible to the eye as a function of the response of the sensor to the substance to be sensed. The images provide the dynamic range of the sensor. Such a sensor can be used to provide a visible image that changes or appears to the eye in response to an analyte. | 10-02-2008 |
| 20080248586 | Reaction Vessel, Reaction Vessel Liquid Introducing Device, Liquid Introducing and Reaction Measuring Device, and Liquid Introducing Device - The invention relates to a reaction vessel, a reaction vessel liquid introducing device, a liquid introducing and reaction measuring device, and a liquid introducing device, and is directed to being able to perform temperature control of a liquid stored within the reaction vessel with a high accuracy and faithful responsiveness. The reaction vessel comprises: a storage chamber in which a liquid is storable, that has an opening part; a reaction chamber that is formed thinner or narrower than the storage chamber; and at least one flow passage that communicates between the storage chamber or the exterior and the reaction chamber. The reaction vessel is formed such that it is connectable to a liquid introducing section provided externally, and the liquid can be introduced into the reaction chamber by connecting to the liquid introducing section. | 10-09-2008 |
| 20080268547 | Systems and Methods for Indicating Oxidation of Consumer Products - The present invention relates to systems and methods using colorimetric indicators of oxidation in consumer products. In particular, betalains are used as oxidation indicators in food, pharmaceutical, and other products. | 10-30-2008 |
| 20080274562 | Method of freezing with brine - Improved brine solutions and uses thereof for uncontaminatedly and/or efficiently freezing items such as foods, and biological samples. In accordance with one embodiment, a brine solution containing a sufficient amount of dye in conferring the solution a distinctive color is used in the freezing process. In accordance with another embodiment, a brine solution containing deionized water is used for improving the freezing efficiency and/or freezing capacity. | 11-06-2008 |
| 20080286879 | Test device, and related methods - Test device for detection and visual indication of a specific analyte in a liquid sample such as a body fluid. The device includes a biodegradable housing, a test strip and a lid. The device is configured for placement in concentrate or dilute test liquid that is for example contained in a vessel. One end of the test strip wicks the liquid being tested into the housing and across a control site and test site which provide visual indication that the device is working correctly and whether the analyte being tested is present in the test liquid. An antibody specific to the antigen being tested may be provided on the test strip. The test device for example detects specific antigens in dilute urine, such that the device may be placed in a toilet bowl after urination. | 11-20-2008 |
| 20080293152 | NANOMEMBRANES FOR REMOTE SENSING - The present invention provides sensors for use in detecting the presence or absence of analytes, systems incorporating the sensors, and methods for using the sensors. The sensors include thin membranes that undergo a detectable geometry change upon exposure to an analyte. In one exemplary embodiment, the sensors are small, thin-film membranes that include a stained semiconductor bilayer, wherein an interaction between the membrane and an analyte induces a detectable change in a strain-induced curvature of the membrane. | 11-27-2008 |
| 20080318335 | Transgenic Plant for Detecting Environmental Chemicals - The present invention provides a plant transformation vector for producing a plant for detecting an environmental chemical by a change of flower color, the plant transformation vector comprising an AhR gene expressibly incorporated therein, an AhR ligand stimulus-inducible promoter, and an expression suppressive factor for suppressing the expression of a gene involved in the synthesis of a desired flower pigment, the factor being expressibly incorporated therein by the promoter. | 12-25-2008 |
| 20090004752 | Chemical composition and method for detecting counterfeit paper currency - A composition and method of detecting counterfeit paper currency includes applying a test solution to a paper currency having ink printed thereon. If the paper currency is counterfeit, the test solution causes the ink to release from the paper currency. If the paper currency is genuine, the ink will not release from the paper currency. The test solution may be an aqueous-alcohol solution having a chemical thickener, and preferably includes a de-foaming agent, a bactericide/fungicide and a fragrance. | 01-01-2009 |
| 20090035871 | Method for measuring maturity degree of compost and measuring solution - A method for measuring the maturity degree of a compost capable of determining the maturity degree of a compost purportedly of a product in a short period of time (10 to 30 minutes) by compost manufacturers, users and even those with insufficient expertise and experiences such as buyers in the distribution industry on site and also capable of determining it according to the maturity stage in an easy and cost-effective manner, and a measuring solution. A specific measuring solution is added to the compost to flocculate a compost extract containing humic-like substance and decomposed organic matter, and a liquid phase is acquired by precipitating the compost extract by the solid/liquid separation. Based on the correlation in which the absorbency of the liquid phase declines as the compost becomes more mature, the maturity degree of the compost is measured from the color contrasting density of the liquid phase. | 02-05-2009 |
| 20090035872 | FLUIDICS SYSTEM - The present invention provides a fluidics system and a method for selectively drawing fluid from at least one selected reservoir into a channel by providing a negative pressure source downstream of the fluid and channel and selectively back filling the selected reservoir with a gas. | 02-05-2009 |
| 20090042311 | ANALYTE SENSOR DEVICES AND HOLDERS, AND METHODS AND SYSTEMS UTILIZING THE SAME - Provided are sensor devices, methods, systems, and kits for measuring the concentration of at least one target analyte. Sensor devices may be mounted into an optical system for measuring the target analyte. Example sensor devices may also be removably mounted in a holder that enables the sensor device to be inserted into a container that allows the sensor device to contact an analyte containing sample. Further provided are methods that include contacting a sensor device with an analyte-containing sample; determining analyte concentration; and optionally repeating these steps to determine if the analyte concentration spikes or exceeds a predetermined level, which may trigger an alarm response. | 02-12-2009 |
| 20090047745 | BULK NEGATIVE INDEX OF REFRACTION MATERIALS WITH RESPONSE IN THE VISIBLE - Bulk negative refractive index materials (NIM) or left-handed metamaterials (LHM) as an amorphous and isotropic solid material consisting of mutually electrically insulated synthetic rings or pucks smaller than the wavelength of visible light. Each ring or puck contains a nanometer sized metallized nucleic acid ring containing one or more non-metallized segments. The bulk material can be formed as a plurality of individual pucks randomly oriented, or as multiple rings stacked together in an axial direction whose axes may be randomly oriented. | 02-19-2009 |
| 20090061530 | METHOD FOR DESIGNATING A COMPONENT HAVING A HEAT INSULATION LAYER AND FOR DETERMINING ITS OPERATING TIME - A method for designating a component, coated with a heat insulation layer including zirconium dioxide (ZrO | 03-05-2009 |
| 20090075391 | Spectroscopic diagnostic method and system based on scattering of polarized light - The present invention provides systems and methods for the determination of the physical characteristics of a structured superficial layer of material using light scattering spectroscopy. The light scattering spectroscopy system comprises optical probes that can be used with existing endoscopes without modification to the endoscope itself. The system uses a combination of optical and computational methods to detect physical characteristics such as the size distribution of cell nuclei in epithelial layers of organs. The light scattering spectroscopy system can be used alone, or in conjunction with other techniques, such as fluorescence spectroscopy and reflected light spectroscopy. | 03-19-2009 |
| 20090081807 | METHOD FOR RAPID AND QUANTITATIVE ASSAY USING PRIMARY COLOR PRINCIPLE - A method for rapid and quantitative assay of fluid specimen is disclosed. This method utilizes the principle of primary colors: any color can be discomposed into three primary colors or multiple primary colors (for example, red, green and blue). The molecules of the chemical being measured are bound to three colored substrates at different binding constant. Thus different concentration of the chemical will result in different final colors chromatography imaging. This makes the quantitative assay possible. This method can also be used to detect qualitatively the existence of multiple chemicals simultaneously. | 03-26-2009 |
| 20090093063 | Color Changing and Coverage Indicating Hand Sanitizer - The present invention includes compositions and methods for detection of the effectiveness of a substance for cleaning that include an electrophilic dye, wherein the electrophilic dye is colorless before exposure to a nucleophilic agent, and an nucleophilic agent, wherein the electrophilic dye, the nucleophilic agent or both are encapsulated and wherein exposure to one or more cognate target or condition triggers the release of the electrophilic dye, the nucleophilic agent or both from encapsulation. It also includes compositions and methods for detection of the effectiveness of a substance for cleaning by a recognitive dye, wherein the dye is colorless before exposure to its cognate target, changes color upon exposure to its cognate target and reverts to being colorless after a predetermined period of time by exposure to one or more environmental agents. | 04-09-2009 |
| 20090098658 | Microchip and Method of Using the Same - A microchip includes fluid circuits therein, formed by uniting together at least a first substrate that is a transparent substrate and a second substrate having grooves provided at the substrate surface and/or through holes penetrating in a thickness direction. The fluid circuits include a liquid reagent receptacle unit to store a liquid reagent, a quantification unit to quantify the liquid reagent or specimen, and an overflow liquid storage unit connected to the quantification unit to store the liquid reagent or specimen overflowing from the quantification unit during quantification. There is also provided a method of using the microchip. | 04-16-2009 |
| 20090104710 | COLORIMETRIC ABSORBANCE MEASUREMENT METHOD, APPARATUS AND SYSTEM - Various embodiments disclose a colorimetric absorbance measurement method and a system for performing the same. The method comprises driving a reaction tray carrying a plurality of reaction cuvettes to rotate at a speed; transferring or rotating filters on a filter wheel to a light path of a light beam, starting from a filter of a first wavelength; and sampling photoelectric data when the light beam has passed through each reaction cuvette in some embodiments. The method ensures consistency in the measurement and synchronization between the calibration and the sample test and reliability of the measurements. Various embodiments simplify data processing and reduce the complexity of the system. | 04-23-2009 |
| 20090111190 | Meander - A centrifugal based microfluidic device that comprises a microchannel structure in which there is a detection microcavity which in the upstream direction is attached to an inlet microconduit for transport of liquid (transport microconduit) to the detection microcavity and which is used for detecting the result of a reaction taking place in the detection microcavity or in a reaction microcavity positioned upstream of the detection microcavity. The detection microcavity comprises a detection microconduit having an inlet part and an outlet part and therebetween an upward or a downward meander. | 04-30-2009 |
| 20090111191 | GAS ANALYZER CASSETTE SYSTEM - A highly sensitive fluid composition analyzer where a fluid may be placed in contact with a very small area on a material sensitized to change color in the presence of a specific type of compound, to be impinged with light. The light reflected, transmitted and/or scattered by the material may serve as input for the analyzer electronics. The fluid may be pre-concentrated prior to being brought in contact with the material. The area on the material may be a spot having an outside dimension of less than one millimeter. | 04-30-2009 |
| 20090124020 | Method for Characterizing the Porosity in Fuel Cell Electrodes - A method for evaluating the composition of an MEA for a fuel cell. The method includes soaking the MEA in an unsaturated organic compound for a predetermined period of time, and then allowing the MEA to dry. The method then includes staining the MEA with osmium tetroxide (OsO | 05-14-2009 |
| 20090142852 | BACTERIORHODOPSIN-BASED SENSORS - A sensor comprising a membrane containing bacteriorhodopsin. In one embodiment, the sensor comprises a layer of purple membrane between a first and a second electrode, wherein the electrodes are connected to a circuit such that a signal is produced when a charge is transferred across the membrane. In another embodiment, the sensor comprises a field effect transistor with a layer of purple membrane deposited on the gate. The layer of purple membrane may be further functionalized by adding fluorophores to the layer of purple membrane. The fluorophores may be deposited adjacent to the layer of purple membrane, or the fluorophores may be attached to the layer of purple membrane with linkages. The fluorophores or linkages between the fluorophores and the purple membrane may be functionalized with receptors to produce sensors for targeted chemical or biological species. | 06-04-2009 |
| 20090148954 | APPARATUS FOR IDENTIFYING EXPLOSIVE MATERIALS - An apparatus for identifying suspected materials, includes: an upper portion and a lower portion; one or more cylinders for containing reactive material; one or more activation handles for releasing the contents of the cylinders, wherein one or more activation handle is slidable along a respective slot in an upper cover portion of the apparatus; one or more piston associated respectively with the cylinders, and with the activation handles, respectively; one or more fixed needle affixed to a frame, wherein a respective tip of the needles is pointed towards a respective bottom stopper of a cylinder, and; reaction chamber affixed below the frame, capable of receiving a flowable agent from the needles. | 06-11-2009 |
| 20090148955 | Label-Free High-Throughput Optical Technique for Detecting Biomolecular Interactions - Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. | 06-11-2009 |
| 20090155919 | High throughput drug screening method - The present invention uses the small temperature changes from reactions and utilizes them in high throughput screening methods. Briefly, a thermal block containing a series of thermally isolated wells is used so that a reaction can take place in each well without affecting the temperature of any other well. A chemical or biological reaction, such as a binding reaction, is allowed to occur in each well or chamber and the optical properties of the all of the wells are monitored using optical, preferably Kromoscopic, measurements. A determination of temperature in each of the wells from those Kromoscopic measurements can be used to determine if reaction occurred. | 06-18-2009 |
| 20090155920 | HIGH THROUGHPUT DISSOLUTION AND PRECIPITATION APPARATUS AND METHOD - A dissolution and precipitation system includes an array of reactors. Each reactor has a mother well and a daughter well having a volume between about one microliter and one milliliter. A fluid transfer system is operable to transfer fluid between the mother well and daughter well and purify the fluid that is transferred to the daughter well from the mother well. A method of testing a plurality of samples includes dissolving a plurality of first solids in each of the mother wells to form a plurality of first solutions in the mother wells. The first solutions are purified in the reactors. The first solutions are distributed from the mother wells to one or more daughter wells. A plurality of second solids are precipitated in the daughter wells and the second solids are analyzed. | 06-18-2009 |
| 20090155921 | METHOD AND APPARATUS FOR READING TEST STRIPS - The present invention provides a method and apparatus for reading test strips such as lateral flow test strips as used for the testing of various chemicals in humans and animals. A compact and portable device is provided that may be battery powered when used remotely from the laboratory and, may store test data until it can be downloaded to another database. Motive power during scanning of the test strip is by means of a spring and damper that is wound by the operator during the insertion of a test strip cassette holder prior to test. | 06-18-2009 |
| 20090155922 | SCREENING TEST FOR BIODIESEL FUEL - A colorimetric test for determining the presence or absence of biodiesel in a diesel fuel sample. The colorimetric test involves adding concentrated sulfuric acid to a sample of diesel fuel and observing any color change of the sample. A darkening of the diesel fuel sample indicates the presence of biodiesel. The degree to which the color changes after the addition of the sulfuric acid is proportional to the amount of biodiesel in the sample and therefore can be used to determine the amount of biodiesel in the sample. The reagent(s), sample containers and any necessary color scale can be provided in a kit for field testing. | 06-18-2009 |
| 20090170213 | High-Throughput Screening of Enantiomeric Excess (EE) - The present invention provides a method for high-throughput screening of enantiomeric excess (ee), comprising synthesizing a sensor made from an aggregate of gold nanoparticles whose surfaces have been elaborated with a chiral “host” that includes two optically pure binaphthol groups linked together by a diethanolamine bridge that is tethered via nitrogen to its associated gold nanoparticle, and in which aggregate the individual particles are held together by a bridging chiral “di-guest,” which contains an amino acid functionality at both ends and which interacts with the surface-bound hosts through hydrogen bonds. To screen, one adds a chiral analyte, which may be the product of an asymmetric catalytic reaction, or some other chiral species, in the form of a scalemic solution to a solution containing the aforemeritioned aggregate wherein one enantiomer of the analyte competes effectively with the “di-guest” for the “host,” while the other does not, and wherein a diastereoselective dispersion of the aggregate occurs, which brings about a large shift in the naked-eye-visible plasmon resonance absorption band of the gold nanoparticles, from a long wavelength for the aggregated nanoparticles to a shorter wavelength for the dispersed particles, and wherein the extent of the colour change is indicative of the degree to which the aggregate is dispersed and provides a rapid and effective measure of the ee of the chiral analyte. | 07-02-2009 |
| 20090176312 | BIOLOGICAL AND CHEMICAL TEST MEDIA AND SYSTEM - An apparatus and method for performing medical, biological or chemical tests in the field is Disclosed. In some embodiments, the test media comprises a special purpose optical disc which is read, after application of the test specimen and subsequent processing using commonly available CD, DVD, High Definition DVD or Blu-Ray optical disc players. | 07-09-2009 |
| 20090186421 | Catalytic Biosensor - The present invention describes a biosening device and method. Specifically, binding of target analyte perturbs the surface of a sensor strip so that gas bubbles are generated in solution. The gas bubbles may be detected for determination of analyte presence in a sample. | 07-23-2009 |
| 20090191643 | Rotatable Test Element - A test element and method for detecting an analyte with the aid thereof is provided. The test element is essentially disk-shaped and flat, and can be rotated about a preferably central axis which is perpendicular to the plane of the disk-shaped test element. The test element has a sample application opening for applying a liquid sample, a capillary-active zone, in particular a porous, absorbent matrix, having a first end that is remote from the axis and a second end that is near to the axis, and a sample channel which extends from an area near to the axis to the first end of the capillary-active zone that is remote from the axis. | 07-30-2009 |
| 20090215191 | Optical Sensor For Detecting Chemical Reaction Activity - The invention provides an optical sensor for detecting chemical reaction activity, including, e.g., enzyme activity and catalytic or reactive molecule activity. An optical sensor of the invention includes a porous photonic film that produces a predetermined spectral reflectance response. In preferred embodiments, the film has a chemical coating (such as a hydrophobic layer) within its pores with an affinity for the reaction product(s) of the catalytic or otherwise reactive analyte A coating can also act as a protective layer in preferred embodiment. A thin substrate susceptible to reaction by at least one analyte of interest is on the surface of the thin film to block pores of the thin film. A method of detecting chemical reaction activity of the invention exposes the optical sensor to an analyte of interest, such as an enzyme or otherwise catalytic or reactive molecule. The optical sensor is subjected to light and the reflectivity spectrum of the optical sensor is monitored for a change indicative of reaction activity. Monitoring can include observation for a visible change or data acquisition via instruments such as a spectrometer for monitoring for a change in interferometric reflectance spectra. | 08-27-2009 |
| 20090221086 | Detection method using metallic nano pattern and the apparatus thereof - The present invention relates to an apparatus and a method for detecting the presence of a particular organic, inorganic, metallic, natural or synthetic biomaterial and the concentration thereof. More particularly, the present invention relates to an apparatus and a method for detecting the identity, presence or absence, and concentration of a material to be detected, by which the metal ions of the detection solution are reduced to metals by a material to be detected and are deposited as metallic nanoparticles, resulting in the change of the shape, size or pattern of the metallic nanoparticles, and the change in light transmittance caused thereby is measured to detect the presence or absence of the material and the concentration thereof. | 09-03-2009 |
| 20090246883 | Paper Tapes Sensitive To Multiple Gases - A sampling tape carries a plurality of elongated, spaced apart, gas sensitive regions which respond to different toxic gases. The regions can be in the form of elongated tracks which can be scanned simultaneously at multiple locations. A group of scanning locations along a track can provide sample signals for a selected gas from a plurality of locations. Signals from another track can relate to a different gas. | 10-01-2009 |
| 20090253214 | Method of optical detection of binding of a material component to a sensor substance due to a biological, chemical or physical interaction and apparatus for its embodiment (variants) - Application: detection of binding of biological and/or chemical components of liquid or gaseous mixtures and solutions, which are of mainly biological origin and/or determine parameters of living activity of biological objects, to substances that bind the said components due to a biological, chemical or physical interaction; and analysis of mixtures and solutions to determine presence of biological and/or chemical components. Essence: binding substances are arranged on a surface of or inside a sensor layer, which changes its thickness due to the binding being detected; the layer is affected by light of different wavelengths; a signal due to interference on the sensor layer is registered in the reflected or transmitted light. In the first variant, the signal is represented by a spectrum; the sensor layer is more than 10 μm thick and exceeds the maximal recorded wavelength by at least an order of magnitude; information about the binding being detected is obtained from analysis of a spectral shift of interference maximums and minimums. In the second variant, the light passes also a scanned Fabry-Perot interferometer; the recorded signal is a dependence of intensity of the resulting light upon changes of base of the scanned Fabry-Perot interferometer, in which maximums due to correlation of the spectral characteristics of interaction of the light with the sensor layer and interferometer are observed; information about the binding being detected is obtained from a shift of the said dependence along values of base. In the third variant, other interferometers are used, which are scanned due to a change of the path difference of interfering beams. The required technical result is to make measurement results independent from uncontrollable variations of intensity of the analyzed light in whole as well as in any part of its spectrum, any areas of the sensor layer, and, consequently, to increase accuracy of measurements and reliability of results, sensitivity and resolution with simultaneous reduction of the number of necessary operations, of labor input and cost of both single- and multi-channel variants including real-time registration. | 10-08-2009 |
| 20090258432 | Composition and Method - A fire-stop product comprising a characterising marker, wherein the presence of said characterising marker can be detected by a diagnostic method at the site where the product is located. | 10-15-2009 |
| 20090258433 | ABNORMALITY-IDENTIFYING METHOD AND ANALYZER - Provided is an abnormality-identifying method for identifying an abnormality of an analyzer which analyzes a specimen based on optical characteristics. All predetermined analysis processes to be performed on the specimen but an analysis process whose abnormality is to be examined are eliminated, and the abnormality of the analyzer is identified based on a measurement result which is obtained through the analysis process whose abnormality is to be examined and a reaction process in which a substance whose abnormality is to be identified or a predetermined reagent is reacted with a predetermined reactant. | 10-15-2009 |
| 20090263912 | NANOWIRES AND NANORIBBONS AS SUBWAVELENGTH OPTICAL WAVEGUIDES AND THEIR USE AS COMPONENTS IN PHOTONIC CIRCUITS AND DEVICES - A microfluidic optical sensor utilizes at least one subwavelength nanowire or nanoribbon waveguide coupled to a fluidic structure having at least one nanofluidic channel through which one or more molecular species are conveyed. In response to optical pumping (e.g., a laser source) the waveguide optically interrogates nearby molecular species retained within said fluidic structure to detect chemical species in response to optical characterization of small (on the order of sub-picoliter) volumes of solution. Characterization is performed in response to evanescent wave sensing. In one aspect, optical characterization is selected from the group of optical characterizations consisting of absorbance, fluorescence and surface enhanced Raman spectroscopy (SERS). | 10-22-2009 |
| 20090263913 | DIFFERENTIALLY ENCODED BIOLOGICAL ANALYZER PLANAR ARRAY APPARATUS AND METHODS - A method of probing a plurality of analyzer molecules distributed about a detection platform is disclosed. The method includes contacting a test sample to the plurality of analyzer molecules, scanning the plurality of analyzer molecules at a rate relating to a carrier frequency signal, and detecting the presence or absence of a biological molecule based at least in part upon the presence or absence of a signal substantially at a sideband of the carrier frequency signal. A molecule detection platform including a substrate and a plurality of targets positioned about the substrate is also disclosed. Specific analyzer molecules adapted to bind a specific analyte are immobilized about a first set of the targets. Nonspecific analyzer molecules are immobilized about a second set of the targets. The targets positioned about the substrate along at least a segment of a scanning pathway alternate between at least one of the first set and at least one of the second set. A method including providing a substrate for supporting biological analyzer molecules the substrate including at least one scanning pathway is also disclosed. The scanning pathway includes a plurality of scanning targets. Specific biological analyzer molecules adapted to detect a specific target analyte are distributed about a first set of the targets which alternate in groups of at least one with a second set of the targets the second set of the targets not including the specific biological analyzer molecules. | 10-22-2009 |
| 20090280572 | Analysis device - A device is disclosed, being an analysis device for the study of biological or chemical samples by means of a reagent liquid supplied via a pipette. The device has an instrument housing with a base plate, a working plate arranged on the base plate horizontally to receive the samples in a sample holder having several wells, a robot manipulator arranged above the working plate, which carries a horizontal support arm with a slide. A needle system is fastened to the slide and can move in the Z direction, carrying 3 needles and being brought into vertical positions by a first vertical drive. The needle tips can be placed in an upper position above and in a lower position below a well. The middle needle can move vertically relative to the other two needles, which can be raised and lowered by a second vertical drive. The horizontal spacing of the three needles is so small that all three needles can be positioned with their tips inside the same wells. In particular, the working plate is mounted on the base plate so that it can turn. | 11-12-2009 |
| 20090298190 | METHOD AND TEST DEVICE FOR DETECTING ORGANIC CORROSION INHIBITORS IN COOLANTS - A test substrate for determining concentration of an organic corrosion inhibitor in a coolant fluid is provided. The test substrate comprises a porous substrate having at least a surface treated with a sufficient amount of at least a metal salt for reacting with a molar equivalent amount of the organic corrosion inhibitor in a representative sample of the coolant fluid, and at least a color indicator. The color indicator reacts with the metal salt and/or the organic corrosion inhibitor, forming an irreversibly colored complex and causing a color change in the test substrate. | 12-03-2009 |
| 20090298191 | Lateral Flow and Flow-through Bioassay Devices Based On Patterned Porous Media, Methods of Making Same, and Methods of Using Same - Embodiments of the invention provide lateral flow and flow-through bioassay devices based on patterned porous media, methods of making same, and methods of using same. Under one aspect, an assay device includes a porous, hydrophilic medium; a fluid impervious barrier comprising polymerized photoresist, the barrier substantially permeating the thickness of the porous, hydrophilic medium and defining a boundary of an assay region within the porous, hydrophilic medium; and an assay reagent in the assay region. | 12-03-2009 |
| 20090305430 | DEVICE FOR PREPARING BONE CEMENT - A method of monitoring the extent of cure of a mixed bone cement includes the steps of taking in hand a flexible polymeric film wherein loaded with a thermochromic material configured to change color at a predetermined temperature; wrapping a quantity of the mixed bone cement in the film such that the film is in contact with and tightly conforms to the mixed bone cement; and monitoring the film to identify a change in the color of the film, the change in the color of the film indicating that the mixed bone cement has reached the pre-determined temperature. | 12-10-2009 |
| 20100009455 | Test Sensor with Under-Fill Protection - A test sensor for testing an analyte concentration in a fluid sample includes a pre-fill capillary, formed by a base and a lid of the test sensor, and a sensing capillary. The pre-fill capillary is in fluid communication with the sensing capillary. The pre-fill capillary is first filled with the fluid sample and a portion of the fluid sample then moves by capillary action to the sensing capillary for testing of the analyte concentration. | 01-14-2010 |
| 20100009456 | FAST BIOSENSOR WITH REAGENT LAYER - A detection system ( | 01-14-2010 |
| 20100009457 | MICROFLUIDIC DEVICE, SAMPLE ANALYZING METHOD USING THE SAME, AND DILUTION RATIO MEASURING METHOD - Provided are a microfluidic device, a method of analyzing a sample using the microfluidic device, and a method of measuring dilution ratios. The microfluidic device includes: a sample chamber which accommodates a sample to be tested; a dilution chamber which accommodates a diluent, receives the sample from the sample chamber, and provides a sample diluent; a first concentration detecting chamber which receives the sample from the sample chamber; and a second concentration detecting chamber which receives the sample diluent from the dilution chamber. | 01-14-2010 |
| 20100015720 | Dynamic desalter simulator - A small-scale dynamic simulator for crude oil refinery desalters has a pressurized oil deviblis configured to hold a supply of crude oil and a water deviblis configured to hold a supply of wash water. At least one chemical feed pump selectively adds emulsion breaker chemicals to the desalter simulator and a low shear metering pump is configured to pump crude oil and wash water through the desalter simulator. An emulsion forming device forms a crude oil-wash water emulsion that is then received in a desalter vessel. The desalting vessel is fitted with electric grids which simulate those found in electric desalters. The emulsion is resolved within the desalter vessel with the assistance of the emulsion breaker chemicals so the wash water and crude oil form distinct phases, with substantially desalted crude oil removed from an upper portion of the desalter vessel and substantially oil-free wash water removed from a bottom portion of the desalter vessel. A portion of the desalter vessel is substantially transparent to allow visualization of the demulsification process and at least one light source is positioned adjacent to the desalter vessel to aid in visualization of a rag layer formed in the desalter vessel. A heated jacket surrounds the desalter vessel to maintain the desalter vessel at the desired temperature. | 01-21-2010 |
| 20100035357 | Apparatus For Optically Reading Test Kits And Identification Data Associated Therewith - A method and an apparatus for optically reading test kits having an identification data zone associated with the test kit and test zone arranged to receive a test substance. The apparatus comprises an optical sensing module, an image-processing module coupled to the optical sensing module, a control module coupled to the optical sensing module and to the image-processing module. The optical sensing module is arranged to sense both the test zone and the identification data zone and deliver the sensed data to the image processing module responsive to the control module. Further, the image-processing unit is arranged to perform image processing on the sensed data from the test zone and from the identification data zone and further determine the test substance according to the sensed data from the test zone in view of the sensed data from the identification data zone responsive to the control unit. | 02-11-2010 |
| 20100035358 | Biological Analysis Systems, Devices, and Methods - A device for performing biological sample reactions may include a plurality of flow cells configured to be mounted to a common microscope translation stage, wherein each flow cell is configured to receive at least one sample holder containing biological sample. Each flow cell also may be configured to be selectively placed in an open position for positioning the at least one sample holder into the flow cell and a closed position for reacting biological sample contained in the at least one sample holder. The plurality of flow cells may be configured to be selectively placed in the open position and the closed position independently of each other. | 02-11-2010 |
| 20100047918 | TEST-SENSOR CARTRIDGE - A test-sensor cartridge including a plurality of test sensors adapted to assist in determining an analyte concentration of a fluid sample. The test-sensor cartridge further includes a housing forming a cavity. The cavity is adapted to contain the plurality of test sensors. The test-sensor cartridge further includes a lid adapted to enclose the cavity. The test-sensor cartridge further includes a closing feature adapted to maintain the lid in a closed position. The closing feature is distorted when the lid is in an open position and generally released when the lid is in a closed position. | 02-25-2010 |
| 20100075433 | ANALYSIS SYSTEM FOR THE PHOTOMETRIC DETERMINATION OF AN ANALYTE IN A BODY FLUID - The invention relates to an analysis system for the photometric determination of an analyte in a body fluid, having an analysis device and a test carrier. The test carrier has an evaluation zone in which a photometrically detectable change takes place as the result of a reaction of a sample of the body fluid which contacts the test carrier with a reagent contained in the test carrier. The analysis device comprises an optical emitter for emitting light onto the evaluation zone, an optical receiver for receiving light from the evaluation zone and for generating a measurement signal corresponding to the received light, and a measurement and evaluation device with a measuring unit and an evaluating unit. The measurement signal is amplified and digitalized in the measuring unit. In the evaluating unit, the concentration value is determined from the digitalized measurement signal. In the evaluating unit, a control value of a control parameter is detected at one detection point during the processing after the calculation step. An error in the measurement and evaluation device is recognized if the deviation of the control value from the expected value exceeds a predefined threshold value. | 03-25-2010 |
| 20100081207 | ASSAY MATERIAL, METHOD OF DETECTING A TARGET USING THE SAME, AND METHOD OF PRODUCING THE SAME - One or more exemplary embodiments providing an assay material including an assay material that includes a substrate, a compound linked to the substrate wherein the compound is linkable specifically to a target, and a patterned region disposed on the substrate wherein the patterned region provides an optical output signal when an incident optical signal is irradiated thereto and wherein the optical output signal corresponds to a code on the substrate. | 04-01-2010 |
| 20100081208 | Multirange indicator - A multirange indicator is proposed which permits quantitative dose determination of high-energy actinic radiation, where the dose for different wavelength ranges can be respectively determined in parallel. To this end, the multirange indicator has two indicator systems designed with mutually corresponding properties, thus eliminating any mutual distortion of the results of the dose measurements. The first indicator system is based on a photolatent Lewis acid or photolatent Lewis base, and the second indicator system is based on a polysubstituted triphenylmethane dye. Both the multirange indicator and its use for the production of various dose-measurement devices are described. Finally, the following are proposed for the measurement of UV radiation and/or electron-beam radiation: as dose-measurement device, a dose-measurement coating material and a flat dose-measurement element, these being based on the above multirange indicator, and also the measurement method that can be implemented with the said dose-measurement devices. | 04-01-2010 |
| 20100105148 | MULTI-CHANNEL SWEPT WAVELENGTH OPTICAL INTERROGATION SYSTEM AND METHOD FOR USING SAME - A multi-channel swept wavelength optical interrogation system and a method are described herein that enable the interrogation of one or more biosensors which for example could be located within the wells of a microplate. In one embodiment, the optical interrogation system comprises: (a) a tunable laser that emits an optical beam which has a predetermined sequence of distinct wavelengths over a predetermined time period; (b) a distribution unit that splits the optical beam into a plurality of interrogation beams; (c) an array of optical interrogation units that receive and direct the interrogation beams towards an array of biosensors; (d) the array of optical interrogation units receive a plurality of reflected interrogation beams from the array of biosensors; (e) a data processing device that receives and processes information associated with the reflected interrogation beams to determine for example whether or not there was a biochemical interaction on anyone of the biosensors. | 04-29-2010 |
| 20100120164 | METHOD USING A NONLINEAR OPTICAL TECHNIQUE FOR DETECTION OF INTERACTIONS INVOLVING A CONFORMATIONAL CHANGE - A nonlinear optical technique, such as second or third harmonic or sum or difference frequency generation, is used to detect binding interactions, or the degree or extent of binding, that comprise conformational change. In one aspect of the present invention, the nonlinear optical technique detects a conformational change in a probe due to target binding. In another aspect of the invention, the nonlinear optical technique screens candidate probes by detecting a conformational change due to a probe-target interaction. In another aspect of the invention, the nonlinear optical technique screens candidate modulators of a probe-target interaction by detecting a conformational change in the presence of the modulator. | 05-13-2010 |
| 20100124787 | CAVITY-ENHANCED ON-CHIP ABSORPTION SPECTROSCOPY - Embodiments of optofluidic devices or methods according to the application can provide on-chip, label-free, massively parallel analysis of analytes. An embodiment of the optofluidic device can comprise a microresonator, a waveguide optically coupled to the microresonator, and a fluidic channel that exposes an analyte to an evanescent field from the microresonator, wherein the light signal has a linewidth lesser than the width of at least one resonance of the light signal propagating in the microresonator. The light signal can be tuned across a spectrum of light wavelengths, wherein the spectrum of wavelengths includes one or more wavelengths defining the at least one resonance in the microresonator. The light transmission through the waveguide over the spectrum of wavelengths of the input light can be detected, and an absorption spectrum of the analyte can be determined. | 05-20-2010 |
| 20100136708 | ANALYSIS DEVICE AND METHOD FOR TESTING THE CATALYTIC ACTIVITY OF SURFACES - In an analysis device and a method for testing the catalytic activity of surfaces, a reaction cell is provided that has a recess for a sample that is provided with the catalytic surface. In the analysis device, an optical test of the reaction occurring in the reaction cell may occur. The reaction cell has a closed channel that is part of a fluid circuit. The reaction cell may be advantageously designed in a very space-saving manner in its scale, such that a portable use of the analysis cell is possible as well. Here, a simple measurement process of the absorption capacity of the sample fluid located in the reaction cell is conducted. To this end, a laser diode is provided, the measurement stream of which is directed into the reaction cell and reflected multiple times. The light intensity is measured by means of a photodetector. | 06-03-2010 |
| 20100136709 | RECEPTACLE AND METHOD FOR THE DETECTION OF FLUORESCENCE - The invention relates to a liquid receptacle comprising a bottom and sidewalls for holding a liquid. The bottom encompasses a flat sensor surface that is in contact with the liquid when the receptacle is filled, a light-incident area that is located below the sensor surface and is suitable for focusing light onto the sensor surface, a light emergence area, and a cover area that is suitable for reflecting light from the sensor surface such that the light can emerge through the light emergence area. The invention further relates to a method for qualitatively or quantitatively determining an analyte in such a liquid receptacle. In said method, excitation light is focused onto the sensor surface via the light-incident area such that a luminescent marker which characterizes the analyte is excited, and the generated luminescence is then reflected onto the cover surface and is detected after emerging through the light emergence area. The invention also relates to an analysis device comprising a holder for a liquid receptacle, a light source that is disposed such that the light thereof can be focused onto the sensor surface of the liquid receptacle via the light-incident area, and a detector which is arranged in such a way as to be able to detect the light emerging from the light emergence area of the liquid receptacle. | 06-03-2010 |
| 20100144052 | Optical Molecular Detection - Optical detection of molecules using a biochip having at least one reagent immobilizing area designed to receive one or more reagents and at least one calibration structure with a predetermined height to provide a height reference for optical measurement is disclosed. When the calibration structure is illuminated by a probe beam of light, a first reflected beam of light is reflected off the calibration structure, and a second reflected beam of light is reflected off the reagent immobilizing area. The first reflected beam and the second reflected beam are compared to determine a height at the reagent immobilizing area. | 06-10-2010 |
| 20100144053 | MULTIPLEX ASSAY READER SYSTEM - A system for reading optical codes includes a set of beads or particles, each of which has a surface functionalization selected for attaching a biomolecule to be studied, and a device for reading an optical code provided by rare earth-based light emitter associated with each of the beads or particles. The device includes an excitation source and a color CCD light detector. The excitation source excites the rare earth-based light emitters of each of the beads, thereby causing the emitters to emit light having a unique ratio of relative intensities, the unique ratio of the relative intensities forming the optical code of the bead or particle. The color CCD light detector detects the emitted light having the unique ratio of the relative intensities and a memory stores an image of the emitted light. | 06-10-2010 |
| 20100159612 | SENSOR CHIP AND METHOD FOR USE THEREOF - A sensor chip has: a light transmitting outer package, a plurality of reaction chambers disposed inside the outer package; a plurality of first induction paths that are connected to the reaction chambers and introduce a sample liquid into the reaction chambers; a first induction path where the induction paths merge; an introducing portion that is connected to the induction path and introduces the sample liquid; second induction paths that are connected to the reaction chambers respectively; a second induction path where the induction paths merge, and a cavity portion constituting a suction portion that is connected to the induction path and sucks the sample liquid. The total lengths of the first induction paths that are connected to different reaction chambers are different from each other, and different types of test reagents are held in the plurality of reaction chambers respectively. | 06-24-2010 |
| 20100173423 | Multiple testing apparatus and method - A multiple test strip assembly comprising a non-bibulous support, a sample application site comprising a defined area of said non-bibulous support delimited by a liquid impervious barrier, and at least two test strips placed on said support, each having a bibulous sample receiving pad, wherein the sample receiving pad of each of said at least two test strips is in contact with said sample application site. | 07-08-2010 |
| 20100178708 | LIQUID FLUID TESTING INSTRUMENT AND TESTING METHOD - Printed surface | 07-15-2010 |
| 20100184232 | METHOD AND APPARATUS FOR OLIGO PEPTIDE SYNTHESIS - An oligo peptide synthesis apparatus comprises a stationary apparatus part, which is stationary in relation to the frame and a movable apparatus part. The movable apparatus part comprises an oligo peptide synthesis reaction holder, which comprises a number of receptors for receiving a corresponding number of vessels and the receptors are located on a circle. The movable apparatus part comprises a revolveable holder, which has a disengageable coupling for connecting the revolveable holder to the oligo peptide synthesis reaction holder. | 07-22-2010 |
| 20100184233 | MATERIAL FOR PRESSURE MEASUREMENT - The invention provides a material for pressure measurement which utilizes a color forming reaction between a colorless electron-donating dye precursor and an electron-accepting compound to form color, and having a color density difference (ΔD) of 0.02 or more before and after pressurization at 0.05 MPa. When the colorless electron-donating dye precursor is included in microcapsules and the median diameter of the microcapsules on a volume basis is A μm, 5000 to 30000 microcapsules having a diameter of (A+5) μm or more are present per 2 cm×2 cm area. | 07-22-2010 |
| 20100184234 | REAGENT FOR MEASUREMENT OF CONCENTRATION OF LEAD, AND METHOD FOR MEASUREMENT OF CONCENTRATION OF LEAD - To provide a lead concentration determination reagent which realizes accurate, high-sensitivity, and simple-manner determination of the lead ion concentration (also referred to simply as “lead concentration”) of a sample solution in the presence of calcium ions, and a lead concentration determination method employing the reagent. | 07-22-2010 |
| 20100197038 | MICROELECTRONIC SENSOR DEVICE FOR OPTICAL EXAMINATIONS WITH TOTAL INTERNAL REFLECTION - The invention relates to a microelectronic sensor device for optical examinations like the detection of target components that comprise label particles ( | 08-05-2010 |
| 20100210028 | MEASURING METHOD USING BIOSENSOR - In a biosensor for measuring the concentration of an object to be analyzed by optical signal detection, when a liquid sample is supplied to a supply part ( | 08-19-2010 |
| 20100221842 | SENSOR DEVICE FOR THE DETECTION OF TARGET COMPONENTS - There is provided a microelectronic sensor device for the detection of target components comprising label-particles, comprising a carrier with a binding surface at which target components can collect; a light source for emitting a light beam incident at the binding surface; a light detector for determining the amount of light in a reflected light beam. In one aspect of the invention, the binding surface is provided by a plurality of aperture defining structures having a smallest in plane aperture dimension (W | 09-02-2010 |
| 20100233822 | DEVICE FOR ANALYZING FLUIDS - It is an object of the invention to provide for an alternative for analyzing fluids. To this end a device for analyzing fluids comprising magnetic particles is provided, the device comprising magnetic means for generating a magnetic field designed for exerting a magnetic force to the magnetic particles creating a movement of the fluid comprising targets and a membrane with an array for moving the fluid through or along the array. | 09-16-2010 |
| 20100240142 | ANALYZING DEVICE AND ANALYZING METHOD USING SAME - A solution component | 09-23-2010 |
| 20100248382 | WAFER PROCESS CHAMBER LEAK DETECTOR - The present disclosure includes a method for monitoring leaks in a wafer process chamber. The method includes providing a wafer process chamber coupled to a gas supply by a gas supply line, wherein an indicator member is coupled to the gas supply line between the gas supply and the wafer process chamber, and a final valve is located on the gas supply line between the gas supply and the indicator member. A gas is supplied from the gas supply to the wafer process chamber through the gas supply line. A light is emitted and directed through the indicator member. The light that was directed through the indicator member is then reflected using a reflecting member. The reflected light is then received and compared to the light emitted in order to determine that the color of the indicator member has changed and a leak has been detected in the gas supply line. | 09-30-2010 |
| 20100248383 | COMBINED OPTICAL AND ELECTRICAL SENSOR CARTRIDGES - A sensor cartridge has a cartridge substrate comprising an optical substrate for optical detection of a target moiety in a sample fluid based on frustrated totalinternal reflection and at least one electric structure. This way, optical read-out and electrical functions, e.g. read-out, are combined in a single substrate, in a simple and cheap manner. Also a method of fabricating such sensor cartridge is provided. | 09-30-2010 |
| 20100248384 | OPTICAL REAGENT FORMAT FOR SMALL SAMPLE VOLUMES - An optical waveguiding optical format enables consistent optical analysis of small sample volumes with minimal variation in light path length among optical formats. The optical format is comprised of an input guide, an output guide, and a sample cavity adapted to allow light to pass through a sample on its way from the input guide to the output guide. A lid removed from the light pathway within the format may be provided with a reagent for assisting fluid analysis. | 09-30-2010 |
| 20100261288 | TIP TRAY ASSEMBLY FOR OPTICAL SENSORS - An apparatus and method for packaging of an optical sensing fiber is disclosed. The apparatus includes a substrate with a plurality of openings, and each opening is configured for holding an optical sensing assembly. The assembly is positioned in the opening with a tip of the assembly extending through the opening to be suspended from the substrate. In addition, openings are arranged so the assembly positioned therein avoids contacting another assembly positioned therein. The apparatus can include a support member for supporting the substrate and positioning the substrate so the tip of the assembly suspended from the opening in the substrate contacts solution in one of a plurality of wells in a container adjacent to the substrate. The assembly can be configured for preparing of the optical assembly for assay. An agitation assembly for agitating the container to create flow of the solution in the container wells over an optical sensing assembly is also disclosed. | 10-14-2010 |
| 20100267163 | NON-SCANNING SPR SYSTEM - A system for measuring an evanescent wave phenomenon at total internal reflection, the system comprising:
| 10-21-2010 |
| 20100273271 | SOLUTION MEASUREMENT METHOD AND SOLUTION MEASUREMENT APPARATUS - A solution measurement method in which a specimen X stored in a capillary | 10-28-2010 |
| 20100291700 | Analysis of membrane component interactions - Devices and methods for detecting interaction between components associated with lipid membranes and analytes are described herein. In certain methods, a surface of a compartment of a device is coated with a material that attaches to lipid membrane from a sample. An analyte is introduced and interaction is detected, for example, by back scattering interferometry. In another method, a surface is passivated with a material that does not bind a lipid membrane. A sample is introduced that contains a membrane comprising a component for testing and an analyte. Interaction is detected. In a third method, a channel is filled with a first liquid that does not comprise a lipid membrane. A bolus of a second liquid that comprises a membrane comprising a component for testing and an analyte is introduced under laminar flow conditions so that a leading edge of the second liquid does not completely displace the first liquid in a sensing area that is interrogated by optical methods, for example, a laser. Interaction between the analyte and the component is detected. | 11-18-2010 |
| 20100311181 | Assay Reader Insert and Method of Maintaining a Reader - An assay reader system incorporating a conventional assay reader, for example a lateral flow reader, and an insert aligned with the reader's sensor to detect an assay result. The insert may include a housing which defines a cavity to receive a removable barrier, wherein the removable barrier can be aligned between the sensor and the test strip. The barrier may include an optical window, and may be cleanable and/or disposable to maintain the accuracy of the reader. Test strips are introduced into the reader through a receiving port within the insert's housing. An air inlet on the insert further maintains the reader's accuracy by allowing air to be tunneled over the housing to remove excess dust, debris, or the like. | 12-09-2010 |
| 20100311182 | METHOD AND APPARATUS PROVIDING ANALYTICAL DEVICE AND OPERATING METHOD BASED ON SOLID STATE IMAGE SENSOR - An analytical system-on-a-chip can be used as an analytical imaging device, for example, for detecting the presence of a chemical compound. A layer of analytical material is formed on a transparent layer overlying a solid state image sensor. The analytical material can react in known ways with at least one reactant to block light or to allow light to pass through to the array. The underlying sensor array, in turn, can process the presence, absence or amount of light into a digitized signal output. The system-on-a-chip may also include software that can detect and analyze the output signals of the device. | 12-09-2010 |
| 20100323454 | ANALYZING DEVICE, AND ANALYZING APPARATUS AND ANALYZING METHOD USING THE ANALYZING DEVICE - A measurement cell ( | 12-23-2010 |
| 20110033948 | METHOD OF READING ENCODED PARTICLES - Microparticles | 02-10-2011 |
| 20110053285 | SENSOR USING MASS ENHANCEMENT OF NANOPARTICLES - Provided herein is a method of detecting a biomolecule, which enhances a mass of the target biomolecule by irradiating light to a photocatalytic nanoparticle binding to the target biomolecule. Accordingly, the method can effectively detect a change in mass, and provide economical and rapid detection using a low-priced photocatalyst. | 03-03-2011 |
| 20110053286 | METHOD AND APPARATUS FOR MOVING STAGE DETECTION OF SINGLE MOLECULAR EVENTS - An apparatus and method based on the apparatus is disclosed for detecting and monitoring chemical and/or bio-chemical reactions or interactions at the single molecule level, where detection and monitoring is improved by moving the viewing field of the detector in a controlled manner. The motion of the moving frame is accomplished either through software in the detector system or is accomplished by moving the reacting system. The motion is controlled and is either linear, circular or elliptical. The motion provides for improved site identification or mapping, improved event detection and monitoring, improved signal recognition and improved noise reduction. | 03-03-2011 |
| 20110059545 | TIME-TEMPERATURE INDICATOR BASED ON OLIGOMERIC SPIROAROMATICS - The present invention relates to a time temperature indicator for indicating a temperature change over time comprising one dimeric or trimeric spiropyran indicator of the formula I or II wherein R | 03-10-2011 |
| 20110065203 | UV-DOSE INDICATOR - The present application provides a uv dose indicator film and ink showing a color change depending on the absorbed radiation-dose, comprising (a) a selected acid responsive colorant; (b) a sulfonyloxime ester compound or a —N—O-sulfonyl compound as photolatent acid. | 03-17-2011 |
| 20110091986 | CHEMICAL ANALYSER, METHOD FOR SAMPLE-BASED ANALYSIS, DEVICE FOR HANDLING CUVETTES, AND LOADING METHOD - With the aid of the invention, a chemical analyser, a method for sample-based analysis, a device for handling cuvettes, and a loading method are provided. The chemical analyser ( | 04-21-2011 |
| 20110097814 | DETECTION DEVICES AND METHODS - The application discloses embodiments of detection devices including a sensor component in a flow path between a first flow path portion and a second flow path portion. In embodiments described, the sensor component includes a receptor in a polymerized composition. The receptor is configured to bind with an analyte in a test sample. Upon binding the sensor component undergoes a detectable change in response to interaction of the analyte with the receptor. | 04-28-2011 |
| 20110111517 | PAPER-BASED MICROFLUIDIC SYSTEMS - Paper-based microfluidic systems and methods of making the same are described. | 05-12-2011 |
| 20110117664 | Reagent, A Kit, And A Method For Detecting And Identifying A Wide Range Of Illicit Drugs - A reagent for detecting and identifying a chemical substance. The reagent is an emulsion including a cobalt salt dissolved in water which also includes at least one organic solvent that is at least partly water-miscible and also including an organic compound which serves as an ion pair color changing indicator or a pH sensitive color changing indicator, the organic compound dissolved in an organic solvent only partly miscible with water. A two product kit for detecting and identifying a chemical substance is also taught. The kit includes the aforementioned reagent and a diazonium salt, typically a diazonium salt having electron withdrawing groups on its phenyl rings. A method for detecting and identifying a chemical substance using the two product kit is also discussed. The reagent, testing kit and method may be used for detecting and identifying controlled substances. | 05-19-2011 |
| 20110117665 | ANALYZING DEVICE, AND ANALYZING METHOD USING THE ANALYZING DEVICE - An analyzing device includes: an operation cavity ( | 05-19-2011 |
| 20110124114 | Assays - A method for assaying a sample for each of multiple analytes is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone comprising a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple test zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte. Capillary structures of the devices or used in the methods may comprise a matrix and the devices may comprise control elements and methods for assaying of sample may use corresponding controlling activities. | 05-26-2011 |
| 20110124115 | Indication enhanced colorimetric detector - The present invention pertains generally to colorimetric indicia provided by a primary device, and more particularly, to at least one indicator moiety influenced by changing environments wherein the indicator moiety exhibits a rapid initial response and a protracted transient time for visualization by an operator. As compared to heretofore colorimetric indicator technologies, the present invention allows for improved accuracy of data interpretation by direct visual capture of changing environments with shorter duration transients. | 05-26-2011 |
| 20110136248 | TRANSILLUMINATION MEASUREMENT DEVICE - The invention relates to a transillumination measurement device for determining the intensity of a chemical/biological reaction, comprising at least one carrier layer, a source and a quantum detector of electromagnetic radiation, and an interface. A reaction membrane is applied to the carrier layer and features at least one chemically/biologically reactive test area. The electromagnetic radiation emitted from the source lies in a first optical spectral range, and the quantum detector features an area that is sensitive to electromagnetic radiation in a second optical spectral range, and the first and second spectral ranges at least partially overlap. The source and the quantum detector of electromagnetic radiation are electrically connected to the interface. | 06-09-2011 |
| 20110136249 | Analyte test system for determining the concentration of an analyte in a physiological or aqueous fluid - This invention provides a device for determining the concentration of an analyte like glucose, cholesterol, free fatty acids, triglycerides, proteins, ketones, phenylalanine or enzymes, in a physiological or aqueous fluid like blood, serum, plasma, saliva, urine, interstitial and/or intra-cellular fluid, the device having an integrated calibration and quality control system suitable for dry reagent test strips with a very small sample volume of about 0.5 μL based on to a new sample distribution system. The production of the inventive analyte test element involves only a small number of uncomplicated production steps enabling an inexpensive production of the strips. | 06-09-2011 |
| 20110136250 | BEAD READER - A method of determining a normalized quantity of an analyte adhering to beads in a detection area of a bead-based assaying system, the method comprising:
| 06-09-2011 |
| 20110165693 | Duration and Environmental Monitoring Compositions, Devices Methods for Preparation and Systems - Duration monitoring co-topo-polymeric compositions and methods for making and using the same are provided. Indicator compositions of the invention include an organic polymer and undergo a color change, which may be reversible or irreversible, in a time dependent manner following an initiation event. Also provided are indicator devices that include the indicator compositions of the invention. The compositions of the invention find use in a variety of different applications. | 07-07-2011 |
| 20110171746 | Variable Penetration Depth Biosensor Methods - A surface plasmon resonance sensor system including a high refractive index prism, a sensor chip, a light source having multiple wavelengths over a broad range of wavelengths, optical lenses, a photodetector, a data acquisition unit, and as defined herein. The sensor chip can include, for example, a thin layer of silicon and gold on one face of a transparent substrate and the prism adjacent to the opposite face of the transparent substrate. Such an arrangement provides variable penetration depths up to about 1.5 micrometers with a dynamic range for sensing index of refraction changes in a sample that are several times greater than that of a conventional SPR sensor. The disclosure provides methods for using the surface plasmon resonance sensor system for cell assay or chemical assay related applications. | 07-14-2011 |
| 20110171747 | BACTERIORHODOPSIN-BASED PHOTOCHROMIC SENSOR FOR DETECTION OF CHEMICAL AND ENVIRONMENTAL TOXINS - A bacteriorhodopsin based chemical sensing architecture based upon the collective response of bacteriorhodopsin and a number of its mutants; the wild type protein and a selection of genetically-engineered variants was able to respond differentially to a selection of amines. The observable response to the presence of a target chemical was manifested through a modulation of bacteriorhodopsin's photokinetic properties, which are monitored through pump-probe techniques using a custom prototype flash photolysis system. Differential responsivity exists at two levels; (1) bacteriorhodopsin proteins (wild-type and genetically-engineered variants) respond differentially upon exposure of a target chemical, and (2) the response pattern exhibited by the proteins differs from chemical to chemical. This dichotomy forms the basis for a BR-mediated chemical sensing technology that is highly sensitive and selective and may therefore discriminate between different chemicals. | 07-14-2011 |
| 20110189785 | PROCESSING UNITS AND METHODS FOR THE PROCESSING OF LIQUID SAMPLES - A microfluidic processing unit for the automated processing of liquid samples and method thereof are disclosed. In one embodiment, the unit comprises first and second main channels connected to a pump for generating a negative or positive pressure therein; a sample channel which supplies a liquid sample is connectable to a sample vessel containing the liquid sample, the sample channel communicates with the first main channel and is equipped with an on/off valve; one or more reagent channels for supplying one or more reagents, the reagent channels being connectable to reagent vessels containing reagents for reacting with the liquid samples, each of the reagent channels communicating with the first or second main channel and being equipped with an on/off valve; and a reaction chamber for reacting a sample and reagent, the reaction chamber being connected to the first and second main channels via at least one on/off valve. | 08-04-2011 |
| 20110189786 | COTTON THREAD AS A LOW-COST MULTI-ASSAY DIAGNOSTIC PLATFORM - Hydrophilic threads as platforms for inexpensive, low volume, portable diagnostic systems, and methods of making the same are described. A diagnostic system includes a hydrophilic loading thread having an inlet zone at a proximal end; a testing zone at a distal end; and an intermediate zone located between the inlet zone and the testing zone, wherein the testing zone does not directly contact the inlet zone. In another aspect, a diagnostic system includes (i) a hydrophilic loading thread that includes an inlet zone at a proximal end and an intermediate zone at a distal end; and (ii) one or more additional hydrophilic threads that contact the intermediate zone of the loading thread. A method of detecting the presence or absence of an analyte in a fluid sample includes applying the sample to an inlet zone of a diagnostic system that includes a hydrophilic loading thread with an inlet zone at a proximal end; an intermediate zone; and a testing zone at a distal end; wherein the testing zone does not directly contact the inlet zone. | 08-04-2011 |
| 20110201125 | METHODS AND RELATED DEVICES FOR CONTINUOUS SENSING UTILIZING MAGNETIC BEADS - A fluidic device including a main channel, wherein a first inlet fluidly connects to an upstream end of the main channel and introduces magnetic beads into a first side of the main channel A second inlet is fluidly connected to the upstream end of the main channel and introduces a sample stream into a second side of the main channel A first magnet disposed adjacent to the second side of the main channel pulls the magnetic beads towards a sidewall of the second side, and thus into the sample stream A second magnet disposed downstream from the first magnet and adjacent to a first side of the main channel subsequently pulls the magnetic beads towards a sidewall of the first side, and thus out of the sample stream A detection region is disposed at or downstream from the second magnet and in the first side of the main channel | 08-18-2011 |
| 20110212537 | METHODS AND SYSTEMS FOR EXTENDING DYNAMIC RANGE IN ASSAYS FOR THE DETECTION OF MOLECULES OR PARTICLES - Described herein are systems and methods for extending the dynamic range of assay methods and systems used for determining the concentration of analyte molecules or particles in a fluid sample. In some embodiments, a method comprises spatially segregating a plurality of analyte molecules in a fluid sample into a plurality of locations. At least a portion of the locations may be addressed to determine the percentage of said locations containing at least one analyte molecule. Based at least in part on the percentage, a measure of the concentration of analyte molecules in the fluid sample may be determined using an analog, intensity-based detection/analysis method/system and/or a digital detection/analysis method/system. In some cases, the assay may comprise the use of a plurality of capture objects. | 09-01-2011 |
| 20110212538 | METHOD FOR DETERMINING AN ANALYTE IN A WATER SAMPLE BY MEANS OF A MOBILE WATER ANALYSIS ARRANGEMENT - A method for determining an analyte in a water sample with a mobile water analyzing system having a basic unit and a test element insertable in the basic unit, the method comprising providing the test element and the basic unit. The test element is inserted into a test element receptacle of the basic unit. The water sample is transported forward from an inlet opening to a measuring section of the test element. A first analyzing of the water sample is performed in the measuring section with an analyzer of the basic unit. The water sample is transported forward from the measuring section to the first reagent section of the test element. The water sample is transported backward from the first reagent section to the measuring section of the test element. A second analyzing of the water sample is performed in the measuring section with the analyzer of the basic unit. | 09-01-2011 |
| 20110223679 | METHOD OF SEEKING AT LEAST ONE ANALYTE IN A MEDIUM LIKELY TO CONTAIN IT - A new method of seeking the presence of an analyte bound to a probe, wherein a periodic geometric pattern ( | 09-15-2011 |
| 20110223680 | Microfluidic Device and Material Manipulating Method Using Same - Microfluidic devices for manipulating relatively dense materials, such as colloidal rod particles, are provided. Microfluidic devices for separating a denser first material from a less-dense second material are provided. Methods of manipulating a relatively dense first material, for example, colloidal rod particles, and separating the first material from a less-dense second material, are provided. Methods of marking samples or sample components with relatively dense materials, are also provided. | 09-15-2011 |
| 20110223681 | MOBILE WATER ANALYSIS ARRANGEMENT AND METHOD FOR DETERMINING AN ANALYTE IN A WATER SAMPLE - A mobile water analyzing system for determining an analyte in a water sample includes a basic unit and a test element configured to be inserted into the basic unit. The test element includes a sample line with an inlet opening configured to receive the water sample, a measuring section forming a measuring track and configured to allow the determination of an analyte, a pump opening, and a key reagent disposed inside the sample line. The basic unit includes a test element receptacle configured to hold the inserted test element, an analyzer with an analyzer measuring track formed by the measuring section, and a pump actuator cooperatively connected with the pump opening. | 09-15-2011 |
| 20110244588 | OPTICAL DETECTION SYSTEMS AND METHODS OF MAKING AND USING THE SAME - An optical sensing device is provided. The device comprises a cavity defined by at least an anomalous reflective element having an anomalous reflection surface, and a non-absorptive element having a non-absorptive reflection surface disposed in a direction away from the anomalous reflection surface. | 10-06-2011 |
| 20110244589 | IN-VIVO PLATELET FUNCTION TEST BY ONLINE BLEEDING VOLUME MEASUREMENT - A method for remotely determining a patient's excessive bleeding tendency and a patient's resistance to blood thinning medication is disclosed. An incision is made in the patient's forearm. Blood oozing out of the incision is absorbed into a blotter paper until the bleeding stops. Blotches of blood formed on the blotter paper are captured as an image and sent to a service provider who calculates a value associated with the bleeding volume of the patient. The service provider retransmits a value associated with the bleeding volume back to the medical professional. To determine the resistance to blood thinning medication, one incision is made in the patient prior to administration of blood thinning medication. Blood oozing out of the incision is collected on blotter paper until the patient stops bleeding. A second incision is made in the patient. A second set of blotter paper is used to collect the blood oozing out of the incision until the bleeding stops. Both sets of blotter paper are sent to a service provider to calculate a value associated with the difference in bleeding volume. The service provider then retransmits the value associated with the difference in bleeding volume to the medical professional. | 10-06-2011 |
| 20110244590 | ANALYSIS APPARATUS AND METHOD - A coloration state of a test region is read out as image density values by a readout device. A calculation is made to find a similarity degree between template information for the test region, which template information represents a state of coloration of the test region, and which has been stored previously in a pattern storing device, and the coloration state of the test region, which coloration state has been read out by the readout device. An analysis of an analyte is performed by a judgment device in accordance with the similarity degree, which has been calculated. | 10-06-2011 |
| 20110244591 | COLORATION ANALYZING APPARATUS AND METHOD - Viscosity of a test body solution spotted onto a test piece is detected. The test piece has an insoluble support, through which the test body solution is developed, and a test region formed on the insoluble support, the test region reacting with an analyte in the test body solution and undergoing coloration. A washing liquid is fed to the test region and its neighboring regions at the time between a stage, at which the test body solution has been developed through the test region, and a stage, at which a liquid for amplifying the coloration state of the test region is fed to the test piece, such that the quantity of the washing liquid fed to the test region and its neighboring regions is set to be large as the detected viscosity becomes high. | 10-06-2011 |
| 20110244592 | OPTOCHEMICAL SENSOR ACTIVE ELEMENT, METHOD OF ITS PREPARATION AND USE - An optochemical sensor element suitable for sensing an analyte comprises a polymeric material in which at least a portion of the polymer material is solvent crazed to provide a multiplicity of pores of controlled nanometer size, and an indicator dye impregnated into the pores, in which optochemical sensor element the indicator dye is a long-decay photoluminescent dye selected from the group consisting of: phosphorescent platinum(II)—and palladium (II) complexes of porphyrin dyes such as octaethylporphine, coproporphyrin, octaethylporphine -ketone, benzoporphine, tetra (pentafluorophenyl) porphine, chlorin e6; fluorescent complexes of ruthenium (II), osmium(II), iridium(III) and europium (III); or derivatives or close analogs of these dyes. The sensor element in the presence of the analyte alters a photoluminescence parameter thus allowing sensing and/or quantification of the analyte. | 10-06-2011 |
| 20110275162 | ASSAY READER OPERABLE TO SCAN A TEST STRIP - Low-cost assay test strip readers are disclosed. Such readers enable creation of profiles of analyte reactions detected on an assay test strip utilizing a simple detector fixedly mounted to a body of the reader. The detector may be a single detector, such as a photodetector, which detects an optical signal at a single point. The assay test strip is inserted and/or removed from the test strip reader and the detector detects the optical elements of the strip during such insertion and/or removal. The movement of the test strip with respect to the body enables the detector to scan a length of the test strip, such that a one-dimensional profile of the optical signals can be generated. The reader may convert the detected profile into a displayable indication of analyte concentrations for diagnostic purposes. Moving the test strip relative to an array of detectors enables creation of a two-dimensional profile. | 11-10-2011 |
| 20110287553 | BREACH OR CONTAMINATION INDICATING ARTICLE HAVING MICROCAPSULES - Provided among other things are breach or contamination indicating elastomeric articles for indicating a breach or contamination by a selected chemical or group of chemicals, the article having an exterior and interior and comprising: (1) an indicating layer that comprises (a) a carrier polymer, and (b) a plurality of microcapsules wherein each microcapsule comprises a dye and a shell, wherein the plurality of microcapsules is dispersed in the carrier polymer and the polymer shell releases the dye in the presence of the selected chemical(s); and (2) an elastomeric layer selected to resist permeation by the selected chemical(s), which resistant layer is to the interior or exterior side of the indicating layer. | 11-24-2011 |
| 20110294224 | Devices, Systems, and Methods for Separating an Analyte From a Mixture, and Devices, Systems, and Methods for Measuring an Amount of an Analyte - Devices, systems, and methods for separating an analyte from a mixture, and devices, systems, and methods for measuring an amount of an analyte are disclosed. The devices, systems, and methods may be used to separate glycated hemoglobin from other blood components and to measure the amount of the glycated hemoglobin. | 12-01-2011 |
| 20110312102 | LIGHT TRANSMISSIVE TEMPERATURE CONTROL APPARATUS AND BIO-DIAGNOSIS APPARATUS INCLUDING THE SAME - A light transmissive temperature control apparatus, a bio-diagnosis apparatus including the transmissive temperature control apparatus, and a method of diagnosing biochemical reaction using the bio-diagnosing apparatus are provided. The light transmissive temperature control apparatus includes at least one tube which is formed of a light transmissive material and configured to contain a sample; and a temperature control unit which accommodates at least a part of the at least one tube which is transparent, guides light to be irradiated onto the at least one tube, and controls a temperature of the at least one tube. | 12-22-2011 |
| 20120021528 | Method for Adding an Apparent Non-Signal Line to a Rapid Diagnostic Assay - A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in the test device becomes transparent, thereby allowing the user to view a mark that is present on a support that is disposed beneath the observation area. Typically, the mark on the underlying support is configured as a minus (−) sign. In the absence of analyte in the sample, the test device presents a negative result as a minus (−) signal. In the presence of analyte in the sample, however, the mark operates in concert with a perpendicular test line on the observation area to present a positive result as a plus (+) signal that is visible to the user. | 01-26-2012 |
| 20120034701 | DEVICE FOR ASSAY OF A LIQUID SAMPLE - Device and detection system comprising two polarising elements and a measuring zone located between said polarising elements, wherein the measuring zone is being bounded on one side by the first polarising element. The device further comprises an inlet reservoir, an outlet reservoir and a flow channel. Method of fabricating said device, comprising the step of depositing an antibody into the measuring zone. | 02-09-2012 |
| 20120058569 | METHOD AND DEVICE FOR DETERMINING REFLECTION COEFFICIENTS ON FILTER ARRANGEMENTS HAVING THIN LAYERS - The invention relates to a method for determining optical properties by measuring intensities on a thin layer, wherein light is irradiated onto a carrier ( | 03-08-2012 |
| 20120077280 | NANOFIBERS WITH MODIFIED OPTICAL PROPERTIES - Nanofibers modified to alter their optical properties in the infrared part of the electromagnetic spectrum, which nanofibers can be used in applications ranging from identification technology to energy conversion devices (e.g., thermophotovoltaics) to stealth technology. The desired optical properties can be obtained by modifying the fibers with rare earth and other materials and then can be incorporated into garments or other composite structures or can be applied as coatings on solid surfaces, to be used in a number of applications that benefit from selective emission properties. | 03-29-2012 |
| 20120083043 | TEMPERATURE-TIME INDICATOR SYSTEM BASED ON IRREVERSIBLE COLOR CHANGES, AND CORRESPONDING METHOD - The present invention relates to a temperature-time indicator system which allows monitoring the maintenance of the cold chain in frozen or refrigerated substances based on irreversible color changes, comprising a layer with a solution of ascorbic acid and a layer with a solution of at least one base, wherein the solution of ascorbic acid does not mix with the solution of at least one base unless the temperature reaches a pre-determined threshold. The invention also relates to a method using said system. | 04-05-2012 |
| 20120094392 | DETERMINATION OF AT LEAST ONE PARAMETER OF A PHYSICAL AND/OR CHEMICAL TRANSFORMATION - Physico-chemical systems subject to transformation are flowed in a flow member, while maintaining the external periphery of the wall of such flow member at one and the same temperature, with the exception of a display zone, at least between two remote points along said member; at least one spatial distribution of the temperature of the physico-chemical system along this display zone is displayed, in particular comprising an infrared camera, and the or each parameter is determined therefrom utilizing the or each spatial temperature distribution. | 04-19-2012 |
| 20120094393 | Heated Reaction Chamber For Processing A Biochip And Method For Controlling Said Reaction Chamber - The invention relates to a heated reaction chamber for processing a biochip and to a method for controlling said reaction chamber. The heated reaction chamber for processing a biochip comprises a chamber wall, constituted by a flexible circuit board ( | 04-19-2012 |
| 20120107949 | TEST SWIPE FOR PORTABLE EXPLOSIVE OR DRUG DETECTION SYSTEM - A portable chemical analytical apparatus to analyze a test swipe having a base; a chemically treated pad containing the swiped sample positioned in a white zone above the base; and a tab attached to one side of the base. The apparatus includes a heater to warm the test swipe to a predetermined temperature; a clamp to secure the test swipe to the heater; one or more pumps to dispense one or more chemicals onto the test swipe from a disposable cartridge; a fan to remove chemical vapors rising a predetermined distance from the test swipe; and a camera to capture an image of the test swipe for un-biased automated analysis, and displayed on an LCD screen. | 05-03-2012 |
| 20120122231 | SPECIMEN TESTING DEVICE AND METHOD THEREOF - The present invention relates to a specimen testing device and method thereof, and it is an object of the present invention to provide a compact and reliable specimen testing device and method thereof. The specimen testing device includes one, two or more test cartridge containers which comprise a plurality of accommodation parts which accommodate or can accommodate a specimen and one, two or more reagent solutions or testing tools used for testing the specimen, and which visibly display specimen information for identifying or managing the specimen and test information showing test content; an automatic testing unit which is attached with or supports the testing tools and which causes a reaction of the specimen and the reagent solution accommodated in the test cartridge containers to obtain a predetermined optical state; an optical measurement unit which measures the optical state obtained by the automatic testing unit; and a digital camera which captures an image of content including the specimen information and the test information and displayed on the one, two or more test cartridge containers to obtain image data. | 05-17-2012 |
| 20120129269 | NANO-OPTIC FILTER ARRAY BASED SENSOR - A device such as a filter or reflector includes a conductive layer including a periodic pattern of elements. The elements have shapes and sizes configured such that a transmittance or reflectance spectrum of the conductive layer has a drop at a long-wavelength end. The elements have a period configured such that the spectrum has a dip at a Plasmon mode resonant wavelength. The spectrum further includes a peal- between the dip and the drop. | 05-24-2012 |
| 20120135535 | AUTOMATED REAL-TIME PARTICLE CHARACTERIZATION AND THREE-DIMENSIONAL VELOCIMETRY WITH HOLOGRAPHIC VIDEO MICROSCOPY - An in-line holographic microscope can be used to analyze on a frame-by-frame basis a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. Through a combination of applying a combination of Lorenz-Mie analysis with selected hardware and software methods, this analysis can be carried out in near real time. An efficient particle identification methodology automates initial position estimation with sufficient accuracy to enable unattended holographic tracking and characterization. | 05-31-2012 |
| 20120156795 | NANOMETRIC INK FOR DETECTION OF EXPLOSIVES - A method of manufacturing an explosive testing agent is disclosed. The method includes synthesizing hydrogen bronze nanoparticles and placing the nanoparticles on a test platform. | 06-21-2012 |
| 20120156796 | CUVETTE FOR PHOTOMETRIC MEASUREMENT OF SMALL LIQUID VOLUMES - A cuvette for photometric measurement of liquids is provided comprising a body having outer walls and an inner space for receiving liquids, the body comprising an upper part comprising an upper open top portion, an upper front wall, an upper back wall, and two upper side walls. The upper walls form four upper inner edges and an upper open bottom portion with a first substantially rectangular cross-section in a plane A-A, a lower measurement chamber comprising a lower closed bottom portion, a lower front wall, a lower back wall, and two lower side walls. The lower walls form four lower inner edges and a lower open top portion with a second substantially rectangular cross-section in a plane B-B smaller than the first substantially rectangular cross-section in the plane A-A, wherein at least the lower front wall and the lower back wall are at least in part substantially planar and substantially parallel to each other. An abrupt transition zone is positioned between the plane A-A and the plane B-B comprising four transition inner edges connecting the four lower inner edges to the upper open bottom portion. At least in the plane B-B the lower inner edges comprise fillets having a first radius (R | 06-21-2012 |
| 20120164745 | NANOFINGER DEVICE WITH MAGNETIZABLE PORTION - A nanofinger device with magnetizable portion. The nanofinger device includes a substrate, and a plurality of nanofingers coupled with the substrate. A nanofinger of the plurality includes a flexible column, and at least one magnetizable portion. At least the nanofinger and a second nanofinger of the plurality of nanofingers are to arrange into a close-packed configuration. The magnetizable portion is to actuate the nanofinger in opening from the close-packed configuration in response to a physical stimulus affecting the magnetic state of the magnetizable portion. A chemical-analysis apparatus including the nanofinger device for chemical sensing and a method of using the nanofinger device for chemical sensing are also provided. | 06-28-2012 |
| 20120178176 | COLOR CODED SWIPE FOR PORTABLE EXPLOSIVE OR DRUG DETECTION SYSTEM - A test swipe for testing drugs, explosives or a chemical compound includes a base; and one or more swipe pads positioned on the base to receive one or more chemicals thereon, the one or more swipe pads displaying an array of colors after receiving the chemicals to uniquely identify a chemical compound. | 07-12-2012 |
| 20120184047 | NANOPLASMONIC DEVICE - The present invention relates to a solution for nanoplasmonic measurement using a nanoplasmonic device with a short range order structure of trough going channels in contact with a fluid flow cell. The device is manufactured in a micro machine process comprising steps of using combined colloidal lithography, thin film deposition and etching steps on the micro/nano scale, for chemical or bio analytical sensing, and other uses. The solution makes use of shifts in the nanoplasmonic resonance, an optical property of the device that is sensitive to changes in refractive index induced by molecular reactions or other processes. | 07-19-2012 |
| 20120184048 | METHOD FOR CHARACTERIZATION OF BIOLOGICAL BONDS - The invention relates to the field of intensity measurements of a light scattering label bound to a surface of a support using an optical evanescent field. According to the invention, the method comprises the steps: a) Providing an assay comprising at least one light scattering label bound to a surface of a support by at least one bond; b) Measuring the fluctuations in the intensity of scattered light of the label in an optical evanescent field over time while the label is bound to the surface. The method according to the invention allows to identify different bonds and/or to distinguish between different bonds. | 07-19-2012 |
| 20120190123 | STRUCTURAL ANALYSIS DEVICE AND STRUCTURAL ANALYSIS METHOD - A molecular structure analysis device of at least one embodiment of the present invention includes: a light source for illuminating, with exciting light, a measurement sample including a molecule to be structurally analyzed to which molecule a rare earth complex is bonded; a measurement section for receiving light emitted from the measurement sample and for measuring intensities of spectra of the light; a calculation section for performing normalization in which intensities of spectra including a line spectrum due to electric dipole transition among the measured intensities of the spectra of the light are normalized by an intensity at one wavelength in a line spectrum due to magnetic dipole transition; and an output section for outputting the spectra whose intensities have been normalized. This makes it possible to attain a device and a method capable of analyzing minute change in a dynamic structure of the molecule. | 07-26-2012 |
| 20120190124 | Reversible Covalent Linkage of Functional Molecules - The present invention relates to the use of a compound containing a moiety of formula (I) as a reagent for linking a compound of formula R | 07-26-2012 |
| 20120202294 | SYSTEMS AND METHODS FOR WAVELENGTH SPECTRUM ANALYSIS FOR DETECTION OF VARIOUS GASES USING A TREATED TAPE - An apparatus including a treated tape, an adjustable color source, a photodiode, and a processor is provided. The adjustable color source emits a first radiation toward the treated tape and operates at each of a plurality of different target wavelengths in a spectrum. The photodiode measures a second radiation reflected from the treated tape, and the processor analyzes measurements from the photodiode to determine a peak wavelength from the plurality of target wavelengths. Based on the peak wavelength, the processor determines a color and darkness of a color stain on the treated tape. Based on the determined color and darkness of the color stain, the processor also determines a type and concentration of gas to which the treated tape is exposed. | 08-09-2012 |
| 20120208287 | REAGENT SYSTEM AND METHOD - The present invention relates generally to a chromogenic compositions and reagents systems and methods therefor. | 08-16-2012 |
| 20120214251 | TEST SET FOR A PHOTOMETRIC MEASURING DEVICE AND PHOTOMETRIC MEASURING METHOD FOR A SAMPLE LIQUID - The invention relates to a test set for a photometric measuring device, comprising a mixing container ( | 08-23-2012 |
| 20120214252 | COMPOSITION, DEVICE AND METHOD FOR COLORIMETRIC DETECTION OF AN ANALYTE USING IMPRINTED POLYMERS AND PHOTOCHROMIC SWITCH MOLECULES - The invention provides various compositions, devices, and methods useful for detecting an analyte by colorimetric readout. The compositions and devices include polymers constructed to have pores specifically imprinted to provide for capture of an analyte in the pores; nanoparticles layered on the polymers; and photochromic optical switch molecules coated on the nanoparticles. Capture of the analyte in the pores of the polymer results in a change in the spatial relation of the nanoparticles layered on the polymer, which in turn causes the photochromic optical switch molecules coated thereon to undergo a change in energy state corresponding to a visible change in the optical spectra of the photochromic optical switch molecules. | 08-23-2012 |
| 20120238032 | LAB ON A CHIP - A Lab On a Chip (LOC) has a Sample Preparation Module (SPM) coupled to a sample inlet, a microchannel coupled to the SPM, and an optic module optically proximate to the microchannel. The optic module holds multiple lenses, each of which has a different effective focal length, such that all fields of focus within the microchannel are covered as objects suspended within the liquid sample pass through the microchannel. | 09-20-2012 |
| 20120244628 | LIQUID ANALYSIS SYSTEM - A liquid analysis system for a photometric determination of an analyte in a liquid sample includes an analyzer comprising a photometer, an RFID parameter reading device and an identifier reading device, and a cuvette package comprising an RFID parameter transponder and a plurality of test cuvettes of one batch. Each test cuvette comprises a reagent. Batch identification and batch-specific reagent data are stored in the RFID parameter transponder. Each test cuvette comprises a batch-specific identifier including a batch identification. The batch identification is configured to be read by the identifier reading device. | 09-27-2012 |
| 20120252131 | BIOLOGICAL MATERIAL ANALYZER AND BIOLOGICAL MATERIAL ANALYSIS METHOD - An analyzer includes a holder for a chip having a spreading layer for a sample including a biological material and a reaction layer with a reagent that reacts with the biological material and generates a chromogenic material, a first light source that applies first light that is absorbed by the chromogenic material, a first detector that detects first output light from the chip irradiated with the first light, a second light source that applies second light that is absorbed by the biological material, a second detector that detects second output light from the chip irradiated with the second light, and a calculation unit that calculates a first concentration of the biological material from the first output light, calculates a spreading state of the sample from the second output light, and calculates a second concentration of the biological material by correcting the first concentration using the calculated spreading state. | 10-04-2012 |
| 20120276653 | Detection Device and Method of Using the Same - A detection device ( | 11-01-2012 |
| 20120309101 | IN-SITU MEASUREMENTS OF SPATIALLY RESOLVED SPECTROSCOPIC DATA WITHIN A REACTOR CHAMBER OF A REACTOR - The invention is directed to a reactor having a reactor chamber and a sensor situated inside the reactor chamber, characterized in that the sensor is a sensor for collecting spectroscopic information. Further, the invention is directed to a method for analyzing a reactor state including the steps of providing said reactor; collecting spectroscopic information from a sample inside the reactor chamber; and analyzing said collected spectroscopic information. | 12-06-2012 |
| 20120309102 | Method for Determining the Antioxidant Power of Biological Vegetal Fluids - A method is described for determining the antioxidant power of biological fluids such as saliva, serum, plasma, urine, sweat, tears and vegetal fluids, such as fruit, vegetables, beverages derived therefrom. Said method proved to be particularly suitable when evaluating the antioxidant power of saliva, which presents particular complexities from the analytical viewpoint. | 12-06-2012 |
| 20120329170 | ANALYZING APPARATUS AND ANALYZING METHOD - An analyzing apparatus contains an image pickup unit and an analysis unit. The image pickup unit contains a view field area that covers at least a reaction area and a background area in a test piece. The reaction area exhibits a reaction color when exposed to a test substance in a specimen. The analysis unit detects the test substance based on the reaction color and determines, during detection of the test substance, whether a state of the background area falls within an acceptable range set for the test substance. | 12-27-2012 |
| 20130005048 | INDICATOR DEVICE - The present invention provides a test device for indicating the presence, concentration and effectiveness of chemical and biological agents. The test device interacts with the target agent producing a detectable signal indicating the presence, concentration and effectiveness of the agent. | 01-03-2013 |
| 20130040400 | METHOD OF STUDYING A SAMPLE IN AN ETEM - A method and apparatus is provided for studying the reaction (chemical or physical) of a sample with a gas in the active atmosphere of an instrument such as an Environmental Transmission Electron Microscope (ETEM), optical microscope, X-ray microscope or scanning probe microscope. The sample is exposed to inert gas at a desired temperature before exchanging the inert gas to the active gas to reduce to avoid, or at least minimize, sample drift during image acquisition. | 02-14-2013 |
| 20130040401 | TEST STRIP READER - In one innovative aspect, systems and methods for modular electronic test kits such that test can be more easily fabricated as well as integrated with other devices is provided. In a further innovative aspect, systems, and methods for test strip readers including improved accuracy of the tests performed by the test reader are provided. | 02-14-2013 |
| 20130045541 | OPTICAL GAS SENSOR - A gas sensor and method for ascertaining the concentration of one or more gas species, in the exhaust gas of an internal combustion engine. The gas sensor includes a measuring cell having a gas inlet, a gas outlet, a catalysis area, and an analysis area. The sensor also includes a catalytic converter for catalyzing a reaction of a first gas species to form a second gas species in the catalysis area, and a gas analyzer for spectroscopically measuring the concentration of the second gas species in the analysis area. Through the catalytic converter, a first gas species may be converted into a second gas species whose absorption and/or scattering wavelength(s) are within the emission wavelength range of semiconductor radiation sources, so that the gas analyzer may have a semiconductor radiation source. | 02-21-2013 |
| 20130052745 | CHEMOCHROMIC MEMBRANES FOR MEMBRANE DEFECT DETECTION - A method of detecting defects in membranes such as ion exchange membranes of electrochemical cells. The electrochemical cell includes an assembly having an anode side and a cathode side with the ion exchange membrane in between. In a configuration step a chemochromic sensor is placed above the cathode and flow isolation hardware lateral to the ion exchange membrane which prevents a flow of hydrogen (H | 02-28-2013 |
| 20130052746 | HIGHER ORDER STRUCTURED DYES WITH ENHANCED OPTICAL FEATURES - Organic dyes that are covalently bonded multimers or higher order symmetrical structures where one or more dye units may optionally contain deuterium substitutions are disclosed. The disclosed dyes are particularly useful for optical coatings, new optical nanomaterials, high density storage devices. The structural and optical characteristics of the disclosed dyes provide avenues for increased information-content through surface-enhanced Raman resonance spectroscopy. | 02-28-2013 |
| 20130059397 | AUTOMOTIVE FOGGING ANALYSES BY XENON UV EXPOSURE - Processes and apparatuses are provided for the liberation of one or more volatile organic compounds from a test sample. The processes include exposing a sample to light of a wavelength less than 400 nm, subjecting the sample to heat, and collecting one or more volatile organic compounds produced from the sample. The volatile organic compounds are detected by any of various methods, and are optionally identified by methods such as FTIR. The processes and apparatus provide for improved detection of relevant volatile organic compounds that are otherwise undetectable by traditional processes. | 03-07-2013 |
| 20130071942 | System and Method for Small Molecule Detection - A system for analyzing a content of a sample material is presented. The system includes a fiber sensitized to a first substance, and at least one electrode configured to expose the fiber to an electric field. The system includes an optical sensor configured to detect a displacement of the fiber when the fiber is exposed to the electric field, and a processor configured to use the displacement of the fiber to characterize a content of the sample material. | 03-21-2013 |
| 20130095572 | ANALYSIS DEVICE, ANALYSIS SYSTEM AND ANALYSIS METHOD - An analysis device of performing predetermined analysis processing to a sample. The analysis device includes: a first analysis unit, a second analysis unit and a simple analysis unit to perform at first analysis process to the sample, a second analysis process to the sample and a short-time analysis process to the sample, by which an analysis result is given in a shorter time than by the first analysis process, respectively; and a judging unit to judge, before a result of the first analysis process is given, whether or not to perform the second analysis process on a basis of a result of the first analysis process. | 04-18-2013 |
| 20130149789 | LIQUID TESTING SYSTEM - A liquid testing system is provided, which includes a distribution module, a testing chip, a driving module and an image analyzing module. The distribution module is for providing a liquid. The testing chip receives the liquid from the distribution module. The driving module is connected to the testing chip and drives the testing chip to rotate, wherein the liquid flowing in the testing chip is actuated by centrifugal force. The image analyzing module produces and analyzes an image of the liquid in the testing chip. | 06-13-2013 |
| 20130183767 | Diffusion/Chemical Reaction/Spectrometric Device for the Analysis of Petroleum Hydrocarbons in Environmental and Geological Formation Samples - An analytical device that provides chemical composition spectrometric data on surface and sub-surface samples is provided. The device provides for the introduction of the liquid or solid sample into a sample chamber where it is extracted by a chlorinated hydrocarbon solvent. The extract then passes into a chamber where it undergoes a Friedel-Crafts (FC) reaction, catalyzed by a polymer-encased Lewis acid. This FC reaction produces characteristic colors, which provide specific quantitative and qualitative chemical information about the hydrocarbon substance. The polymer chain then passes into a module containing a spectrometer consisting of a tungsten/halogen light source, a diffraction grating, and a CCD-based detector that reads the spectral information and sends the digital information to a microprocessor. The microprocessor is not described in this patent application as many types exist, which will perform the necessary operations for analysis, storage, and transmission of the spectral data. | 07-18-2013 |
| 20130210161 | METHOD FOR PREPARING A SAMPLE FOR ANALYSIS - A well plate ( | 08-15-2013 |
| 20130217141 | METHOD FOR DETERMINING AN ANALYTE IN AN AUTOMATED MANNER - A method for determining an analyte of a liquid sample in a cuvette includes providing a cuvette, a reagent, a barcode, an icon on the cuvette and a liquid analysis device comprising a photometer, a rotation device, a camera, a calibration data memory storing first calibration data, and an input device which manually inputs second calibration data. The cuvette is inserted into the liquid analysis device and is rotated to align the icon with the camera. The icon is read with the camera and the icon read compared with an icon model stored in the liquid analysis device to determine whether it corresponds thereto. The liquid sample is subjected to photometry based on the first calibration data if the icon read corresponds to the icon model. If not, the input apparatus is activated and the liquid sample is subjected to photometry on the basis of the second calibration data. | 08-22-2013 |
| 20130217142 | ARTICLE FOR BIOLOGICAL ANALYSIS - The present invention generally relates to the field of analysis, for example biological analysis. More specifically, the present invention relates to an article, especially for biological analysis, the article including: a first sheet, a second sheet, superimposed on the first sheet, the first and second sheets being joined on all of their sides in order to form a sealed package, at least one analysis device, placed inside the package, a rigid desiccation device, also constituting a device perforating the first or second sheet of the package, in order to access the analysis device, and one of the first and second sheets contains a notch which constitutes a preferential folding area. | 08-22-2013 |
| 20130224875 | TIME-TEMPERATURE INDICATING DEVICE - The present invention is generally in the field of measuring and indicating techniques and relates to a time-temperature indicating device and methods of manufacturing and reading this device. More specifically, the time-temperature indicator (TTI) device comprises at least one active reactant being at least a part of a component that is configured to be either an electrical component or transformable into an electrical component, said at least one active reactant being selected to be affectable by a chemical and/or physical reaction effecting a change in at least an electrical property of said electrical component at a rate that is time-temperature dependent. | 08-29-2013 |
| 20130224876 | A METHOD AND DEVICE FOR DETECTING ALKYLATING AGENTS - A method is provided for detecting alkylating agents, the method comprising bringing together a first solvent, one or more surfactants, a base, a reagent comprising a nucleophilic nitrogen atom, and a suspected alkylating agent. A device suitable for putting said method into effect is also provided. | 08-29-2013 |
| 20130244337 | Systems and Methods for Analyte Detection - This disclosure provides a system component and method for analysis of airborne analytes by absorbing the analytes into a liquid and interrogating the liquid with an analytical instrument. In some examples, a cartridge with a microfluidic chip contains a vessel of a colloidal solution of nanostructured particles in a liquid. The vessel is broken, releasing the solution into microfluidic containers on the chip. Air having analytes is passed over the chip leading to absorption of airborne analytes into the solution. The analytes bind with the nanostructures and are detected optically. Techniques are disclosed for filling the vessel in a way that maintains the efficacy of the solution until it is needed for measurement. | 09-19-2013 |
| 20130252343 | METHOD FOR PRESERVING AQUEOUS SOLUTION CONTAINING LEUCO CHROMOGEN - The present invention provides: a method for preserving an aqueous solution containing a leuco chromogen, comprising adding a compound having at least one substituent selected from the group consisting of a nitroso group and an azo group and having an ability to coordinate a metal ion or a salt thereof to the aqueous solution containing a leuco chromogen; a method for stabilizing a leuco chromogen, comprising allowing the leuco chromogen to coexist in an aqueous solution comprising a compound having at least one substituent selected from the group consisting of a nitroso group and an azo group and having an ability to coordinate a metal ion or a salt thereof; and a liquid reagent comprising a leuco chromogen and a compound having at least one substituent selected from the group consisting of a nitroso group and an azo group and having an ability to coordinate a metal ion or a salt thereof. | 09-26-2013 |
| 20130267034 | INTERMOLECULAR INTERACTION MEASUREMENT METHOD, MEASUREMENT SYSTEM FOR USE IN THE METHOD, AND PROGRAM - A measuring method of an intermolecular interaction for optically measuring an intermolecular interaction between a plurality of substances on a thin film, the method comprising: detecting intensity at a first wavelength of reflected light or transmitted light before start of the intermolecular interaction with a detection unit which detects the reflected light from the thin film or the transmitted light transmitted through the thin film; detecting intensity at the first wavelength of the reflected light or the transmitted light after the start of the intermolecular interaction with the detection unit; and calculating a difference in intensity of the reflected light or the transmitted light at the first wavelength between before and after the start of the intermolecular interaction. | 10-10-2013 |
| 20130280818 | LIGHT ABSORBANCE MEASUREMENT METHOD AND APPARATUS - Methods and apparatuses for measuring a light absorbance are provided. The method measures light absorbance of at least one detection chamber of a microfluidic device, including the detection chamber and at least one reference chamber. The detection chamber may accommodate a test subject. The method includes detecting a plurality of reference transmitted light intensities for the at least one reference chamber and estimating a value between the plurality of reference transmitted light intensities through nonlinear approximation. The estimated value is then applied to light absorbance measurement of the detection chamber to reduce a light absorbance error of the detection chamber. | 10-24-2013 |
| 20130288381 | PORTABLE EXPLOSIVE OR DRUG DETECTION SYSTEM - Systems and methods are disclosed to automatically detect the presence of a substance on a test swipe by capturing a background image of the test swipe; adjusting the temperature of the test swipe to a predetermined temperature range; capturing an in-situ image of the test swipe after the application of chemical at the predetermined temperature range; subtracting the background image from the in-situ image; generating a difference value from the two images; and searching a known database to identify the substance. | 10-31-2013 |
| 20130295682 | METHOD OF OPERATING AN OPTOCHEMICAL SENSOR - An optochemical sensing device has source that emits radiation of a first and a second predetermined intensity, a detector, and a sensitive element that comprises a signal substance. To measure an analyte in a measurement medium, the sensitive element is contacted with the analyte. A first raw signal, which is dependent on the analyte content is obtained by exciting the signal substance with radiation of the first predetermined intensity. At a later time, a second raw signal is also obtained. A comparison of the raw signals yields a comparison value, which is compared against a predetermined limit value. If the comparison value exceeds the limit value, the radiation source is set at the first intensity. If the comparison value is smaller than the limit value, the radiation source is set at the lower second intensity. Using the lower radiation intensity prolongs the life of the sensitive element. | 11-07-2013 |
| 20130323854 | OPTICAL SENSOR FOR DETERMINING QUATERNARY AMMONIUM COMPOUND CONCENTRATION - The present disclosure generally relates to a dye that signals when the concentration of a quaternary ammonium compound in antimicrobial solution changes. A sensor is used to monitor changes in the dye wavelength as an indicator of the quat concentration. The use of a sensor leads to improved precision in measuring quat concentration by eliminating or reducing operator bias in reading color or wavelength changes. The dye can be incorporated into a variety of articles including towels, labels, containers, buckets, trays, sinks, spray bottles, liners for containers, buckets, sinks, or spray bottles, indictor wands or strips, and test kits. | 12-05-2013 |
| 20130323855 | DEVICE FOR HOLDING A SAMPLE - A device is provided for holding a sample for optical examination. The device comprises a body that defines a plurality of spots or wells. One or more non-specific interacting surfaces in the spots or wells are capable of non-specific binding of a said sample, a luminophore label, or their combination. A light conducting layer comprises material that is essentially non-transparent to optical excitation radiation and essentially transparent to optical luminescent radiation. A light input window couples luminescent light into said light conducting layer, and a light output window couples light out from said light conducting layer. | 12-05-2013 |
| 20130323856 | RAMAN SCATTERING NANOPROBES - A Raman scattering probe, and a method of making such a probe, uses a capsule of nanometric size, such as a nanotube, to which is coupled at least one Raman-active molecule. The Raman-active molecule may be encapsulated in, or attached on the exterior of the capsule, and exhibits a Raman scattering response when the probe is illuminated by an excitation light beam. A functionalization chemical group that is attached to an exterior of the capsule provides a connection between the capsule and a target material. This functionalization may include a generic chemical functionalization that bonds with any of a plurality of secondary chemical groups each of which bonds directly with a different target. A method of using the probe for Raman spectroscopy or Raman imaging is also provided. | 12-05-2013 |
| 20130337574 | METHOD FOR DETERMINING A SHAPE CORRECTION VALUE F FOR LABORATORY LIQUID-ANALYSIS CUVETTES - A method for determining a shape correction value F for a laboratory liquid-analysis cuvette comprising a cuvette body with a circular cross-section for a photometric liquid analysis includes optically measuring an inside diameter d | 12-19-2013 |
| 20140011288 | SYSTEM AND METHOD FOR ANALYZING A SAMPLE LIQUID - The present invention provides a system for analyzing a sample liquid comprising a test tape having a plurality of test elements, a tape transport device which successively transports the test elements to a sample application site while advancing the tape, and a measuring device which scans the test elements loaded with sample liquid at a measuring site. The measuring site is located at a distance from the sample application site in the direction of tape movement. The tape transport is interrupted in order to exactly position a wetted area of the test elements carrying a sample liquid at the measuring site by means of a positioning device that responds to the presence of sample liquid on the test element. | 01-09-2014 |
| 20140017801 | Monitoring of Photo-Aging of Light-Based Chemical Indicators Using Illumination-Brightness Differential Scheme, and Systems, Methods, Apparatuses, and Software Relating Thereto - Photo-aging monitoring of light-based chemical indicators that experience performance degradation as the cumulative amount of light exposure from measurement and/or reference illumination increases from usage. Differing regions on a chemical indicator are illuminated with measurement illumination light of differing exposures, for example, higher brightness, longer exposure times, or both. Readings from the differing regions are compared with known aging information for the chemical indicator at issue to determine a confidence factor for the measurements. The confidence factor can be used to control various actions relating to measurements acquired from the chemical indicators, such as compensating measurement readings for photo-aging, assigning confidence levels to measurement readings, and issuing alerts to users when photo-aging exceeds one or more predetermined thresholds. | 01-16-2014 |
| 20140017802 | METHOD TO IDENTIFY CHEMICAL COMPOUNDS USING COLORIMETRIC SPOT TESTS - A method to identify a compound of interest includes the step of subjecting a sample to a plurality of colorimetric spot tests to yield a plurality of resultant test colors. The resultant test colors are compared with reference colors to define a set of sample reference colors. Indexed reference color sets indexed for the compound of interest are provided. The indexed reference color sets are searched with one or more of the sample reference colors for a match with the set of sample reference colors. The identity of the sample as the compound of interest is then determined. A device and a system to identify compounds of interest are also disclosed. | 01-16-2014 |
| 20140038305 | ARTICLES AND METHODS FOR THE DETECTION AND QUANTIFICATION OF ULTRAVIOLET LIGHT - Formulations, articles and methods for the detection and/or qualification of ultraviolet light. A chemical formulation containing a tetrazolium or formazan complex is used to make a UV sensitive compound. The formulation is used to form a chemical indicator comprising a substrate with the formulation impregnated on or in the substrate. The substrate may be any suitable material and may be coated, uncoated, or laminated. The formulation may be coated on or inserted into a substrate and will form a UV detecting indicator when applied thereto. Depending upon its composition, the formulation will undergo a color change on exposure to different types of ultraviolet radiation, such as UVA, UVB or UVC, and the color change can be correlated to the length of exposure. The indicator can be used to detect and evaluate exposure to ultraviolet light in a variety of settings depending on the specifics of the formulation. | 02-06-2014 |
| 20140051178 | SPECIMEN TEST UNIT - A self-contained specimen testing unit consisting of a swab-tip with attached, hollow swab-stick, an outer, elongated, removable tube housing cover that surrounds and protects the swab-tip and swab-stick, a dropper removably secured to the end of the tube cover, a dropper cap, a piercing closure member, a rotatable base closure member coupled to the piercing closure element, a membrane member mounted in the base closure member, and reagent-solution storage container screwed onto the end of the rotatable base closure member and sealed by the membrane member thereof. A method of using the unit is also disclosed whereby the piercing unit pierces the membrane when reagent solution is to be delivered to the swab-tip. | 02-20-2014 |
| 20140051179 | System for Visual and Electronic Reading of Colorimetric Tubes - Gas detector tubes may be used to determine a concentration of target gases in air. The gas detector tubes described may be read either by and optical reader or visually by the user. A gas detector tube reader having an optical reader capable of reading a length of stain, a color change and color density of a reagent in a gas detector tube. The gas detector tube may further comprise sensors for measuring the environmental conditions during sampling. | 02-20-2014 |
| 20140073061 | URINE GENDER TEST KIT - A kit and methods for determining the gender of an unborn fetus. The kit comprises a container holding a solid composition therein, the solid composition including a basic salt and a transition metal separated by a filler and in which an atmosphere in the container is substantially free of water. | 03-13-2014 |
| 20140080223 | Systems and Methods for Inspecting and Monitoring a Pipeline - Disclosed are systems and methods for inspecting and monitoring an inner surface of a pipeline. One system includes a pig arranged within the pipeline and having first and second ends, one or more optical computing devices arranged on at least one of the first and second ends for monitoring a fluid within the pipeline. The optical computing devices including at least one integrated computational element configured to optically interact with the fluid and thereby generate optically interacted light, and at least one detector arranged to receive the optically interacted light and generate an output signal corresponding to a characteristic of the fluid. The system also includes a signal processor communicably coupled to the at least one detector of each optical computing device for receiving the output signal of each optical computing device and determining the characteristic of the fluid as detected by each optical computing device. | 03-20-2014 |
| 20140080224 | Systems and Methods for Inspecting and Monitoring a Pipeline - Disclosed are systems and methods for inspecting and monitoring an inner surface of a pipeline. One system includes a pig arranged within the pipeline and having a housing that defines a conduit therein for providing fluid communication through the pig, one or more optical computing devices arranged on the conduit for monitoring a bypass fluid flowing through the conduit. The one or more optical computing devices including at least one integrated computational element configured to optically interact with the bypass fluid and generate optically interacted light, and at least one detector arranged to receive the optically interacted light and generate an output signal corresponding to a characteristic of the bypass fluid. A signal processor is communicably coupled to the at least one detector of each optical computing device for receiving the corresponding output signals and determining the characteristic of the fluid. | 03-20-2014 |
| 20140147928 | METHOD FOR ASCERTAINING A TRANSMISSION VALUE - The invention is in the field of in vitro diagnostics and relates to a method for ascertaining a transmission value for a light signal that is pulsed at a frequency through a specimen in an automatic analysis appliance. It also relates to a transmission measurement apparatus for an automatic analysis appliance, comprising a light source that is pulsed at a frequency and a photodetector having a downstream A/D converter. | 05-29-2014 |
| 20140162372 | DEVICE FOR MEASURING ELECTROLYTE IONS USING OPTODES AND USES THEREOF - Provided is a device for measuring electrolyte ions that is capable of providing a uniform pH environment in the region of an optode, and a method of measuring electrolyte ion concentration using the device. | 06-12-2014 |
| 20140220700 | CAPILLARY ABSORPTION SPECTROMETER AND PROCESS FOR ISOTOPIC ANALYSIS OF SMALL SAMPLES - A capillary absorption spectrometer and process are described that provide highly sensitive and accurate stable absorption measurements of analytes in a sample gas that may include isotopologues of carbon and oxygen obtained from gas and biological samples. It further provides isotopic images of microbial communities that allow tracking of nutrients at the single cell level. It further targets naturally occurring variations in carbon and oxygen isotopes that avoids need for expensive isotopically labeled mixtures which allows study of samples taken from the field without modification. The method also permits sampling in vivo permitting real-time ambient studies of microbial communities. | 08-07-2014 |
| 20140242714 | AIR MONITORING SYSTEM AND METHOD - A filter element having filter media for filtering air passing therethrough and a detection strip attached thereto comprising a chemical compound that generates a chemical reaction with certain molecules that contact the detection strip. | 08-28-2014 |
| 20140242715 | Detection of Volatiles in Personal Care Products - Color-change compositions for detecting urine and feces volatiles include the following pH indicator dyes: m-Cresol Purple, Basic Fuchsin, Brilliant Blue G, Brilliant Blue R, Cresol Red and Thymol Blue. The compositions may be applied to various substrates. Such substrates may be used in the construction of a personal care absorbent article such as a diaper, training pant or incontinence garment. | 08-28-2014 |
| 20140256056 | METHOD TO CALIBRATE DISPOSABLE CARTRIDGE CUVETTE THICKNESS IN-SITU - An analytical system includes a laser disposed to direct light toward a microfluidic feature disposed in a feature layer of a multiple layer test cartridge, a sensor to receive reflections from capping layers disposed about the microfluidic feature in the feature layer, and a controller to determine a depth of the microfluidic feature as a function of the received reflections. | 09-11-2014 |
| 20140287520 | System and Method for Optical Detection Using Capillary Action - A system and method for the detection of one or more analytes in a collected sample employs capillary action in a sample card containing a sample substrate, at least one test capsule and an absorbent pad. The absorbent pad absorbs the contents of the test capsule and delivers the same to the sample substrate, with the contents of the test capsule chemically reacting with at least one detection reagent to establish an optical indicator for the analyte(s). The sample card can be automatically tested within a reader device, which records and processes an optical signal produced by the chemical reaction and outputs a test result. The collected sample can then be further analyzed using a second device. Additionally, an adhesive component can be provided so that a sample can be collected thereon. Furthermore, the at least one detection reagent can include a surfactant. | 09-25-2014 |
| 20140295571 | METHOD AND ASSEMBLY FOR DETERMINING THE TEMPERATURE OF A TEST SENSOR - An assembly determines an analyte concentration in a sample of body fluid. The assembly includes a test sensor having a fluid-receiving area for receiving a sample of body fluid, where the fluid-receiving area contains a reagent that produces a measurable reaction with an analyte in the sample. The assembly also includes a meter having a port or opening configured to receive the test sensor; a measurement system configured to determine a measurement of the reaction between the reagent and the analyte; and a temperature-measuring system configured to determine a measurement of the test-sensor temperature when the test sensor is received into the opening. The meter determines a concentration of the analyte in the sample according to the measurement of the reaction and the measurement of the test-sensor temperature. | 10-02-2014 |
| 20140322816 | PORTABLE EXPLOSIVE OR DRUG DETECTION SYSTEM - A portable chemical analytical apparatus to analyze a test swipe includes a heater to warm the test swipe to a predetermined temperature; a clamp to secure the test swipe to the heater; one or more pumps to dispense one or more chemicals onto the test swipe from a disposable cartridge; a fan to remove chemical vapors rising a predetermined distance from the test swipe; and a camera to capture an image of the test swipe for automated analysis. | 10-30-2014 |
| 20140342464 | Package Including an Anti-Counterfeit Indicator - A package including a container and an anti-counterfeit indicator that can indicate whether or not a product dispensably disposed within the container is authentic or counterfeit when it is exposed to a sample of the product. The indicator may be configured to produce a response upon detecting a certain chemical compound in the product that is indicative of the authenticity of the product. | 11-20-2014 |
| 20140349409 | REAGENT CARD ALIGNMENT SYSTEM AND METHOD - A reagent card analyzer comprises an optical signal source configured to transmit an optical signal and an optical signal detector spaced a distance from the optical signal source to define an optical signal path into which the optical signal is transmitted, the optical signal detector configured to detect the optical signal and to output an electrical signal indicative of the optical signal. A reader is configured to read a reagent pad of a reagent card. A reagent card moving mechanism is configured to move the reagent card having the reagent pad including a leading and trailing end through the optical signal path. An optical detector interface is electrically coupled with the optical signal detector and configured to receive electrical signals and to output a pad detect signal indicative of at least one of the leading and the trailing end as the reagent card is moved through the optical signal path. | 11-27-2014 |
| 20140370615 | USE OF OPTICALLY ANISOTROPIC PARTICLES - This invention relates to the use of optically anisotropic particles in order to non-destructively test or determine physical system parameters and/or the microscopic structure of systems. The mobility of the optically anisotropic particles is used to examine physical system parameters and/or the microscopic structure of systems. To this end, particle mobility is measured via an optical system. | 12-18-2014 |
| 20140377879 | ASSAY DEVICES AND METHODS - A device for determining an assay result may include a test strip, a light source system, a light detection system, and a processor. | 12-25-2014 |
| 20150056714 | METHOD FOR CHARACTERIZATION OF THE REDOX CONDITION OF CEMENTITIOUS MATERIALS - Disclosed are methods for determining the redox condition of cementitious materials. The methods are leaching methods that utilize an in situ redox indicator that is present in the cementitious materials as formed. The in situ redox indicator leaches from cementitious material and, when the leaching process is carried out under anaerobic conditions can be utilized to determine the redox condition of the material. The in situ redox indicator can exhibit distinct characteristics in the leachate depending upon the redox condition of the indicator. | 02-26-2015 |
| 20150087076 | APPARATUSES, INDICATORS, METHODS AND KITS WITH TIMED COLOR CHANGE INDICATION - An apparatus, method and kit includes one or more use protocol indicators having a color changeable dye, the dye being translucent or having a first color upon immediate exposure to an environment and for a defined time thereafter and the dye changing color after exposure to the environment for the defined time. A dual environment indicator includes a first indicator color changeable dye being translucent or having a first color upon immediate exposure to a first environment and changing color after exposure to a second environment and a second indicator color changeable dye being translucent or having a first color upon immediate exposure to the second environment and for a defined time thereafter and changing color after exposure to the second environment for the defined time. A time exposure indicator comprises at least one color changeable dye disposed to change color in a sequential manner. | 03-26-2015 |
| 20150290638 | CHEMICAL SEQUENCING AND CONTROL TO EXPAND AND ENHANCE DETECTION CAPABILITIES UTILIZING A COLORIMETRIC TEST - In some embodiments, the present disclosure pertains to a colorimetric system for detecting a substance, the colorimetric system that includes a first chemical container adapted for releasing a first chemical; a second chemical container adapted for releasing a second chemical; a flow modulation sheet adjacent each chemical container; and an encapsulation covering the flow modulation sheet and each chemical container, where the encapsulation comprises a window defining a target area of the filter paper such that the target area is adapted for applying the substance; where the flow modulation sheet comprises a design adapted for automatically controlling a first flow of the first chemical and a second flow of the second chemical to the target area. | 10-15-2015 |
| 20150293079 | Hazardous Material Detection and Isolation Distance Apparatus and Method - Disclosed herein is a first responder hazardous material detection and isolation distance (HMDID) apparatus and method that addresses the disconnect that exists in two current first responder tools: a means for detecting a hazardous material, but also the need for an immediate action plan to secure a dangerous area and prevent harm to individuals, such as first responders present at an emergency scene. The detection apparatus comprises test membranes configured to detect a hazardous material present in the atmosphere, by producing a visual color change when exposed to air contaminated with the hazard. The test membranes are attached to a planar form, such as a flat paper card, and are accompanied by an isolation indicator and action item for isolating an area depending on the level of hazardous material present in the atmosphere. | 10-15-2015 |
| 20150301031 | ELECTRONIC TEST DEVICE DATA COMMUNICATION - Electronic test devices and methods include data transfer capabilities. In one implementation, an assay device includes wireless communication capabilities to send assay result decisions and/or values to a separate processing and display device such as a smartphone. In another implementation, light sources are modulated both for performing an assay and encoding and transmitting a result of an assay. | 10-22-2015 |
| 20150330904 | COLORMETRIC SENSOR DETECTING ANALYTES WITH VISUAL EXAMINATION - Provided is a colorimetric sensor whose color is changed from an A color to a B color after being exposed to analytes and which adds a dye or pigment complementing the A or B color so as to induce the color change from a black color to another color thereby maximizing a color contrast effect. The colorimetric sensor according to embodiments of the present invention includes a color change detecting part in which an indicator of which a color is changed according to presence and absence of the analytes and a dye which complements the color of the indicator are mixed, wherein the analytes are detected using a color change of the color change detecting part. | 11-19-2015 |
| 20150352550 | DISCRETE ELEMENTS FOR 3D MICROFLUIDICS - A module may be provided with at least one opening, the opening being an endpoint of a microfluidic channel that passes through at least part of the module. A set of multiple such modules may be arranged into an arrangement of modules, which may be coupled together using one or more coupling mechanisms included on each module. The arrangement of modules may fit within a regular polyhedral grid, and each module within the arrangement of modules may have a form suitable for arrangement of the modules within the regular polyhedral grid. Fluid may then flow through at least a subset of the arrangement of modules via the microfluidic channel of each module of the subset of the arrangement of modules. Some modules may include sensors, actuators, or inner microfluidic channel surface coatings. The arrangement of modules may form a microfluidic circuit that can perform a microfluidic circuit function. | 12-10-2015 |
| 20150353580 | GOLD NANOPARTICLES AND METHODS OF MAKING AND USING GOLD NANOPARTICLES - Disclosed herein are embodiments of gold nanoparticles and methods of making and using the gold nanoparticles. The disclosed gold nanoparticles have core sizes and polydispersities controlled by the methods of making the gold nanoparticles. In some embodiments, the methods of making the gold nanoparticles can concern using flow reactors and reaction conditions controlled to make gold nanoparticles having a desired core size. The gold nanoparticles disclosed herein also comprise various ligands that can be used to facilitate the use of the gold nanoparticles in a variety of applications. | 12-10-2015 |
| 20150377780 | PLASMONIC PROJECTED DIFFRACTION SENSOR - A device for detecting an analyte includes a light source emitting substantially monochromatic light; a two-dimensional diffraction element that interacts with the light from the light source, the diffraction element having one or more features that can generate plasmon waves upon receipt of the light from the light source, at least some of the features being configured to interact with the analyte; and a two-dimensional image sensor facing the diffraction element to receive diffracted light from the diffraction element so as to detect a diffraction pattern projected thereto and to measure a two-dimensional spatial change in the diffraction pattern that occurs as a result of the analyte interacting with the feature of the diffraction element. | 12-31-2015 |
| 20150377782 | Terahertz system - The present invention relates to a terahertz system for generating and time-resolved incoherent detecting of THz radiation, said system comprising a pulse laser light source ( | 12-31-2015 |
| 20160025638 | TEST STRIP METER WITH A MECHANISM FOR PUSHING THE TEST STRIP AGAINST AN OPTICAL READER - The present invention relates to a system, method, and meter for determining the concentration of an analyte in a fluid sample provided on a test strip. The meter ( | 01-28-2016 |
| 20160041103 | LAB-ON-A-CHIP FOR ALKALINITY ANALYSIS - Described is a lab-on-a-chip device and a method of employing a lab-on-a-chip device for determining the concentration of species present in the water. | 02-11-2016 |
| 20160051235 | FECES SAMPLING AND DETECTING DEVICE AND METHOD FOR DETECTING FECES BASED ON THE DEVICE - The present invention provides a feces sampling and detecting device and a method for detecting feces based on the feces sampling and detecting device. The device includes a detector, a casse with detecting strips provided in the detector, a collector accommodated in the detector detachably, a feces sampler for sealing the collector detachably, and at least one puncturing part arranged at a bottom of the detector facing one side of the collector. The feces sampling and detecting device can detect collected feces quickly, thereby avoiding feces sample from nature changing in an interval period, and preventing liquid in the collector from entering the detector to influence safety of the device of the present invention. | 02-25-2016 |
| 20160097709 | MOBILE WATER ANALYSIS - An embodiment provides a method, including: operating a motor to position sample fluid within a fluid channel of a cuvette; transmitting light through an optical chamber of the cuvette; measuring a value of received light that has been transmitted through the optical chamber; comparing the measured value of light to one or more thresholds; determining a position of the sample fluid within the fluid channel based on a comparison from the comparing step; and generating a response based upon the position of the sample fluid with the fluid channel. Other aspects are described and claimed. | 04-07-2016 |
| 20160131627 | REACTION CARRIER, MEASURING SYSTEM AND MEASURING METHOD FOR DETERMINING GAS AND PARTICLE CONCENTRATIONS, AND OPTICAL FLOW SENSOR - A measuring system ( | 05-12-2016 |
| 20160180625 | PCDA-PHBV ELECTROSPUN ADHERENT MATS AS AUTHENTICATION FEATURE | 06-23-2016 |
| 20160184817 | CAP FOR MONITORING OBJECTS IN SUSPENSION - A vessel is for storing and monitoring a suspension of microscopic objects, which comprises a cap suitable for closing off the vessel. The cap includes a fluidics system, which includes an inlet and an outlet. The inlet and the outlet are arranged to be in an interior volume of the vessel when the cap is closing off the vessel. The cap also includes a measurement region for optical microscopy, which includes a sample region suitable for the suspension. The sample region is in fluid connection with the fluidics system. The cap also includes a pump suitable for inducing a flow in the fluidics system. A particular monitoring system and setup is for monitoring cells in a cell culture liquid. | 06-30-2016 |
| 20160187164 | Biological disc and method of positioning the biological disc - A biological disc and method of positioning the biological disc is presented. The biological disc includes a manufacturing information data zone on the outermost peripheral for storing data corresponding to characteristics and limitations of the biological disc, a plurality of flow paths, and a biological detecting zone on the outer peripheral. The testing start mark is used to mark starting point for counting testing chambers. Dividers are disposed between a plurality of testing mark, upper positioning mark, and lower positioning mark. The testing chamber is displayed in the testing mark. The lower positioning mark is positioned across the lower half of the testing mark and the upper positioning mark is positioned across the upper half of the testing mark used for positioning the testing mark. | 06-30-2016 |
| 20160202188 | METHOD OF ASSESSING HAIR COLOUR CHANGES | 07-14-2016 |
| 20160252460 | QUANTIFYING COLOR CHANGES OF CHEMICAL TEST PADS INDUCED BY SPECIFIC CONCENTRATIONS OF BIOLOGICAL ANALYTES UNDER DIFFERENT LIGHTING CONDITIONS | 09-01-2016 |
| 20160377641 | REACTION VESSEL MOVING MEMBER FOR MOVING REACTION VESSELS FROM A PROCESSING TRACK TO A ROTATING DEVICE IN A DIAGNOSTIC ANALZYER - A diagnostic analyzer includes a rotating device, a first optical reader, and a second optical reader. The rotating device includes a first darkened compartment, a second darkened compartment, and an optical path along which the first darkened compartment and the second darkened compartment travel. The first optical reader is operable to read the first darkened compartment and the second optical reader is operable to read the second darkened compartment. | 12-29-2016 |
| 20180024045 | Pipette Tip, Pipette, Apparatus and Kit for Light Measurement | 01-25-2018 |
