Entries |
Document | Title | Date |
20080213864 | Apparatus For Producing And Handling A Flowing Substance | 09-04-2008 |
20080220500 | Human Elongase Genes, Uses Thereof, and Compounds for Modulating Same - The present invention relates to elongase genes, their polypeptides and their control regions, and the use of such genes, polypeptides and control regions in determining compositions for use in the treatment of disease. The identified compositions regulate the expression of the elongase genes or modulate the activity of their protein products. The nucleotide and amino acid sequences are taught for ELG4, ELG6 and ELG7. The control sequences and function are taught for ELG1, ELG2, ELG3, ELG4, ELG5, ELG6 and ELG7. | 09-11-2008 |
20080227176 | HIGHLY EFFICIENT GAS PERMEABLE DEVICES AND METHODS FOR CULTURING CELLS - This invention relates to methods and devices that improve cell culture efficiency. They include the use of gas permeable culture compartments that reduce the use of space while maintaining uniform culture conditions, and are more suitable for automated liquid handling. They include the integration of gas permeable materials into the traditional multiple shelf format to resolve the problem of non-uniform culture conditions. They include culture devices that use surfaces comprised of gas permeable, plasma charged silicone and can integrate traditional attachment surfaces, such as those comprised of traditional tissue culture treated polystyrene. They include culture devices that integrate gas permeable, liquid permeable membranes. A variety of benefits accrue, including more optimal culture conditions during scale up and more efficient use of inventory space, incubator space, and disposal space. Furthermore, labor and contamination risk are reduced. | 09-18-2008 |
20080233630 | Apparatus and Method for Magnetically Separating Cells From Mixture - According to the conventional process of separating necessary cells from a cell mixture containing specific cells tagged with magnetic beads, there is a problem in that separation process is complicated when the separation efficiency is high whereas the separation efficiency is relatively low when the separation process is simplified. The present invention provides an apparatus and method for separating cells from a cell mixture simply and efficiently through the processes of creating a cell mixture layer between upper and lower plates by adjusting a gap between the upper and lower plates and of adjusting a thickness of the created layer and separating the layer while applying a magnetic field to the layer from the upper plate, wherein the lower plate is provided with a cell mixture holding portion, in which the cell mixture containing specific cells tagged with magnetic beads is accommodated in an upwardly convex shape, at a top surface thereof and the upper plate is positioned above the lower plate to face each other and to adsorb the cell mixture accommodated in the cell mixture holding portion of the lower plate into a bottom surface thereof. | 09-25-2008 |
20080248552 | METHOD OF CELL CULTURES AND DEVICE FOR IMPLEMENTING IT - The invention generally provides a cell culture vessel having at least one first zone and at least one second zone, wherein the first zone is a transfer zone for a culture medium which essentially contains no cells and the second zone is a cell culture zone. The invention further includes methods utilizing the cell culture vessel. | 10-09-2008 |
20080274536 | Culture Double Container and a Method of Culture - A culture container and a method of culture which do not require a plurality of incubators in a case where a plurality of cells of different kinds which like different gas concentrations should be cultured simultaneously. | 11-06-2008 |
20080286851 | Large-scale photo-bioreactor using flexible materials, large bubble generator, and unfurling site set up method - A closed photo-bioreactor, which in at least one example comprises a plurality of flexible, repeating, substantially enclosed, parallel chambers flexibly connected along their lengths, where a liquid growth media is substantially still without the need for turbulent mixing of the bulk liquid. In many examples, each is connected into integrated, flexible pipelines that serve to supply gas to the chambers, to vent gas from the chambers, and to fill and drain the individual photo-bioreactor chambers of their liquid contents. In some installations, a bioreactor will be rolled up using, for example, a long rod as a spool, for storage and transportation. Some examples will be manually unfurled and positioned on an angled site including, for example, an earthen berm. In many embodiments, a photo-bioreactor will be manufactured from thin plastics using low cost manufacturing techniques. In at least one example, a photo bioreactor is described in which bubbles with a substantially non-convex shape are introduced to mix the liquid contents. | 11-20-2008 |
20090035839 | Metabolically engineered cells for the production of resveratrol or an oligomeric or glycosidically-bound derivative thereof - A recombinant micro-organism producing resveratrol by a pathway in which phenylalanine ammonia lyase (PAL) produces trans-cinnamic acid from phenylalanine, cinnamate 4-hydroxylase (C4H) produces 4-coumaric acid from said trans-cinnamic acid, 4-coumarate-CoA ligase (4CL) produces 4-coumaroyl CoA from said 4-coumaric acid, and resveratrol synthase (VST) produces said resveratrol from said 4-coumaroyl CoA, or in which L-phenylalanine- or tyrosine-ammonia lyase (PAL/TAL) produces 4-coumaric acid, 4-coumarate-CoA ligase (4CL) produces 4-coumaroyl CoA from said 4-coumaric acid, and resveratrol synthase (VST) produces said resveratrol from said 4-coumaroyl CoA. The micro-organism may be a yeast, fungus or bacterium including | 02-05-2009 |
20090098635 | METHOD FOR SUPPLY OF STARTER CULTURES HAVING A CONSISTENT QUALITY - The present invention relates to the field of producing starter cultures. In particular, a method for customers in need of a starter culture with a consistent quality, is provided. Specifically, the method involves the use of subsets of a stock inoculum material, which comprises a concentrate of starter culture organism cells to be propagated for direct inoculation of a cultivation medium, to obtain a starter culture whereby the conventional stepwise preparation of inoculum material for the production of a starter culture can be avoided. This novel method can be used for the manufacturing of starter cultures for the food, feed or pharmaceutical industry. Furthermore, the method is useful in the cultivation of cells expressing desired products, such as primary and secondary metabolites, including e.g. enzymes and flavours. | 04-16-2009 |
20090155885 | DEVICE AND METHOD FOR THE INCUBATION OF CELLS - Device for the incubation of cells comprising a sterile or sterilisable, portable receptacle for enclosing in a contamination-proof manner at least one integrated and/or insertable culture vessel for accommodating cells with at least one closable opening for introducing and/or removing cells and/or culture medium and/or a culture vessel into and/or from the receptacle and at least one device for creating culture conditions in the receptacle. | 06-18-2009 |
20090170183 | Microtiter Plate and Use Thereof - The invention relates to a microtiter plate and use thereof for conducting fermentation under fed-batch conditions. In order to produce a microtiter plate which permits screening under fed-batch conditions, the invention proposes that the cavities ( | 07-02-2009 |
20090186397 | Product - The invention relates to a microorganism growth substrate which comprises a sterile nutrient composition derived from the biomass of a culture of bacteria including methanotrophic bacteria and further containing at least one sterile nutrient. A preferred biomass material is that derived from a microbial culture comprising | 07-23-2009 |
20090215149 | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics - The invention provides isolated polypeptide and nucleic acid sequences derived from | 08-27-2009 |
20090215150 | Sample container and filtration apparatus and method of filtration using the same - A sample container and filtration apparatus is described comprising a sealable sample container and a surface that is configured to interface with a vacuum base. When the surface interfaces with the vacuum base, a portion of the sample container is broached, providing a pathway for the vacuum source to pull the sample therethrough. In exemplary embodiments, the broachable portion of the sample container comprises an actuating valve. The method for using the sample container and filtration apparatus significantly reduces the possibility of contamination of the sample and during the sample testing procedure relative to the conventional devices and procedures, provides more consistent and reliable test results, and significantly reduces the number of preparation and testing steps for the testing procedure. | 08-27-2009 |
20090221054 | Biogas system - A biogas system includes a fermenter having a first fermenting chamber and a second fermenting chamber for the fermentation of a fermenting medium. Biogas formed in the first fermenting chamber can be introduced into a riser pipe disposed in the second fermenting chamber. | 09-03-2009 |
20090258407 | TEMPERATURE TRANSFER DEVICES - A portable temperature transfer device for transferring thermo energy to and/or from a laboratory culture plate is provided as well as its methods of use. The temperature transfer device comprises a base and a raised stage that comprises a thermal conductive material. The raised stage allows direct contact between individual wells of the laboratory culture plate and the temperature transfer device. | 10-15-2009 |
20090305386 | LOW OXYGEN BIOLOGICALLY MEDIATED NUTRIENT REMOVAL - The present invention is directed to a substantially odorless biologically mediated treatment process for solid and liquid organic wastes. The present invention also provides for a novel nutrient rich humus material produced from the biologically mediated treatment process. The bioconversion process of the present invention results from low electron acceptor concentrations and high quantities of microorganisms in a diverse microbial community. | 12-10-2009 |
20090317891 | PLANT ACTIVATION OF INSECT TOXIN - Compositions and methods for protecting a plant from an insect pest are provided. In particular, nucleic acid sequences encoding insect protoxins modified to comprise at least one proteolytic activation site that is sensitive to a plant protease or an insect gut protease are provided. Cleavage of the modified protoxin at the proteolytic activation site by a protease produces an active insect toxin. Methods of using the modified insect protoxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided. Particular embodiments of the invention further provide modified insect protoxin compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds. | 12-24-2009 |
20100003737 | PARTIALLY FLUORINATED SULFONATED SURFACTANTS - The present invention comprises a compound comprising Formula 1A, 1B, or 1C | 01-07-2010 |
20100041124 | MULTI-STAGE CSTR BIOREACTOR SYSTEM EQUIPPED WITH CELL RECYCLE UNIT - The present invention relates to a single CSTR bioreactor equipped with a cell recycle unit, and a multi-stage CSTR bioreactor system in which 2-7 such single CSTR bioreactors are connected in series with each other. According to the present invention, multi-stage fermentation is carried out in the bioreactor equipped with the cell recycle unit, and thus the production of products (alcohols, organic acids, antibiotics, recombinant proteins, etc.) by anaerobic or aerobic microbial fermentation can be increased, and in addition, a final product can be obtained at high concentration, thus improving the productivity and economic efficiency of a microbial process. | 02-18-2010 |
20100055764 | CELL CULTURE APPARATUS AND METHOD - Cell culture apparatuses and methods for culturing cells include bags for culturing cells. The bags are folded and unfolded to control cell culture conditions. As the bags are folded, segmented sealed chambers for culturing cells are formed. As the bags are unfolded, the segments are unsealed allowing for exchange of fluid between the regions of the subchambers. | 03-04-2010 |
20100075400 | LOW-COST MICROBIAL HABITAT FOR WATER QUALITY ENHANCEMENT AND WAVE MITIGATION - A low-cost aquatic structure optimized for water quality enhancement and wave mitigation. The structure is preferably comprised predominantly of recycled polymer scrap or other low-cost, high-surface-area materials, such as jute. The structure may be either buoyant or non-buoyant. Buoyant embodiments of the structure are preferably tip resistant. All embodiments are preferably wave damping. The structure is preferably porous and permeable, and has a large internal surface area for colonization by nutrient-removing microbes. The structure may alternately be used to add nutrients to a water body to promote fish growth for aquaculture applications. | 03-25-2010 |
20100086987 | SURFACE TREATED CALCIUM CARBONATE AND ITS USE IN WASTE WATER TREATMENT - The present invention relates to a process for the purification of water, wherein a surface-reacted natural calcium carbonate is brought into contact with the water to be purified, the surface-reacted natural calcium carbonate being the reaction product of a natural calcium carbonate with an acid and carbon dioxide, which is formed in situ by the acid treatment and/or supplied externally. | 04-08-2010 |
20100099164 | METHOD FOR CONTROLLING THE GROWTH OF CELL CULTURE - In a method for controlling the growth of microbes grown in a medium to high cell-densities by the fed-batch technology, a two-phase system, having a liquid phase (cultivation medium) and a solid or gel phase, the solid or gel phase provides a source of substrate-delivering polymer which is turned by an enzyme in a controlled way into a growth-limiting substrate or pH adjusting agent. Also described is a method for restricting the synthesis of growth-limiting metabolites and preventing oxygen-depletion in microbial cell cultures. | 04-22-2010 |
20100178685 | METHOD AND DEVICE FOR AERATION, PARTICULARLY FOR MICROBIOLOGICAL FERMENTATION AND FOR CELL CULTIVATION - The invention relates to a method and a device for aeration, particularly for microbiological fermentation and for cell cultivation in a closed chamber. The invention comprises a sterilizable reactor ( | 07-15-2010 |
20100184193 | OVEREXPRESSION OF AMINOACYL-tRNA SYNTHETASES FOR EFFICIENT PRODUCTION OF ENGINEERED PROTEINS CONTAINING AMINO ACID ANALOGUES - Methods for producing modified polypeptides containing amino acid analogues are disclosed. The invention further provides purified dihydrofolate reductase polypeptides, produced by the methods of the invention, in which the methionine residues have been replaced with homoallylglycine, homoproparglycine, norvaline, norleucine, cis-crotylglycine, trans-crotylglycine, 2-aminoheptanoic acid, 2-butynylglycine and allylglycine. | 07-22-2010 |
20100190235 | METHODS FOR DESIGNING AND OPERATING PHOTOBIOREACTOR SYSTEMS - The invention may include methods of configuring and operating a photobioreactor system with modular photobioreactor units or blades. The invention may also include apparatus and methods of controlling the photobioreactor system and optimizing growth conditions through a support structure and backplane interface. | 07-29-2010 |
20100190236 | System for Producing Microorganisms - The invention relates to a device for producing biomass containing any species of microalgae and cyanobacteria, and more generally any microorganisms whose growth depends on photosynthesis in a liquid medium. | 07-29-2010 |
20100248330 | Flow-Controlling Header - An apparatus and method for holding a membrane, screen or other flexible planar body in tension, while providing a conduit for water or other liquid to flow to the membrane being held. The membrane extends from inside a manifold body that carries the liquid, and the manifold body supports the membrane at one edge while the membrane is pulled in tension. Liquid pressure builds up inside the manifold body, preferably by entering a pressure chamber at the top of the manifold body. At a feeding pressure in the pressure chamber the liquid is distributed to the membrane for microbe growth. The liquid can be elevated to a higher, microbe-harvesting pressure by increasing the pressure in the pressure chamber, thereby deflecting a shim separating the pressure chamber from the membrane. The change in pressure is carried out by manually or automatically opening and closing a conventional water valve. | 09-30-2010 |
20100255560 | METHOD AND APPARATUS FOR CAPTURING VIABLE BIOLOGICAL PARTICLES OVER AN EXTENDED PERIOD OF TIME - Method and apparatus for acquiring a sample of viable biological particles from ambient air, and maintaining the collected viable biological particles at temperature and humidity conditions selected to maintain the viability of the collected viable biological particles. In at least one embodiment, spent collection surfaces are stored in a magazine, and the temperature and humidity conditions in the magazine are controlled. In at least one embodiment, viable biological particles are extracted from ambient air using a particle collector contained in a housing, and the temperature and humidity conditions in the housing are controlled. In at least one embodiment, the temperature and humidity of ambient air entering a particle collector are manipulated to levels selected to maintain the viability of collected particles. | 10-07-2010 |
20100297734 | Fusion Tag Comprising an Affinity Tag and an EF-Hand Motif Containing Polypeptide and Methods of Use Thereof - The application discloses a fusion tag comprising an affinity tag and a polypeptide comprising one or more EF hand motif(s). Preferably, said fusion tag comprises a polyhistidine tag, one or more EF hand motif(s) of calmodulin and a thrombin cleavage site. Methods of using said fusion tag to purify a polypeptide of interest are also disclosed. | 11-25-2010 |
20100304466 | System for Supplying an Automatic Inoculating Device and Process Using Such an Automatic Device - A supplying system for an automatic inoculating machine for a sample on a substrate, characterized in that it includes a turret mobile in rotation, preferably around an axis substantially vertical, and an arm mobile in rotation, preferably around an axis substantially horizontal, carried by the turret, at a distal end of the aforesaid arm including means to fix a stylus, and means for raising or lowering the arm. | 12-02-2010 |
20100330651 | SYSTEM AND METHODS FOR ANAEROBIC ENVIRONMENTAL MICROBIAL COMPARTMENTALIZED CULTIVATION - The invention described below relates to an enclosed cell sorting device and methods of using the device. The device is constructed so that the entire process of cell sorting can be conducted under fully anaerobic conditions to retain viability of anaerobic cells before, during, and after cell sorting. This is accomplished by creating an anaerobic atmosphere for the high speed cell sorter and all its components and by the use of airlocks that allow the introduction of anaerobic containers into the chamber containing the sample. | 12-30-2010 |
20100330652 | METHOD AND DEVICE FOR PHOTOCHEMICAL PROCESS - Photochemical process and device adapted to breed, produce, or hydrocultivate microorganisms. The process includes conveying a reaction medium in a reactor in a meander-shaped way that includes moving the reaction medium along a direction that perpendicularly or inclined at an angle to an imaginary horizontal plane, wherein, during the conveying, the reaction medium moves in the reactor at least once along a first direction defined as one of a top down direction and a direction of gravity, moves in the reactor at least once along a second direction defined as one of a bottom up direction and against the direction of gravity, and moves in the reactor one of freely under atmospheric pressure and while exposed to the atmosphere. The process also includes introducing into and removing from the reactor the reaction medium in a continuous manner. | 12-30-2010 |
20110003366 | METHODS OF USING PNEUMATIC BIOREACTORS - A pneumatic bioreactor includes a vessel containing a fluid to be mixed and at least one mixing device driven by gas pressure. A first embodiment includes a floating impeller that rises and falls in the fluid as gas bubbles carry it upward to the surface where the gas is then vented, permitting the impeller to sink in the fluid. The floating impeller may be tethered to a second impeller with a flexible member and pulley. The mixing speed is controlled with electromagnets in the vessel acting upon magnetic material in the impeller or its guides. In another embodiment, floating pistons mix the fluid, pushing it through a mixing plate with one or more apertures. In a third embodiment, the mixing device is a rotating drum with bubble-catching blades and rotating mixing plates with apertures. The top of the vessel for these mixers may include a closed top and sterile filters. | 01-06-2011 |
20110070625 | NOVEL FLUORESCENT PROTEINS AND METHODS FOR USING SAME - The present invention provides nucleic acid molecules encoding novel red fluorescent proteins from | 03-24-2011 |
20110124087 | PHOTOBIOREACTOR - A method of operating a closed photobioreactor for cultivation of phototrophic microorganisms. The photobioreactor comprises a culture liquid and is partially or completely surrounded by water of a water body. A density difference between the culture liquid and the surrounding water is provided so that the position of the photobioreactor in the water body is controlled. A closed photobioreactor for cultivation of phototrophic microorganisms. The photobioreactor is adapted to comprise a culture liquid and to be partially or completely surrounded by water of a water body. The photobioreactor comprises means for determining the density difference between the culture liquid and the surrounding water. | 05-26-2011 |
20110129899 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL, 4-HYDROXYBUTANAL, 4-HYDROXYBUTYRYL-COA, PUTRESCINE AND RELATED COMPOUNDS, AND METHODS RELATED THERETO - The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO), 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine pathway comprising at least one exogenous nucleic acid encoding a BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine pathway enzyme expressed in a sufficient amount to produce BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine and further optimized for expression of BDO. The invention additionally provides methods of using such microbial organisms to produce BDO, 4-hydroxybutyryl-CoA, 4-hydroxybutanal or putrescine. | 06-02-2011 |
20110129900 | LOW OXYGEN BIOLOGICALLY MEDIATED NUTRIENT REMOVAL - The present invention is directed to a substantially odorless biologically mediated treatment process for solid and liquid organic wastes. The present invention also provides for a novel nutrient rich humus material produced from the biologically mediated treatment process. The bioconversion process of the present invention results from low electron acceptor concentrations and high quantities of microorganisms in a diverse microbial community. | 06-02-2011 |
20110159572 | MICROORGANISMS FOR THE PRODUCTION OF 1,4-BUTANEDIOL - The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO. The invention additionally provides methods of using such microbial organisms to produce BDO. | 06-30-2011 |
20110201089 | METHODS FOR INCREASING PRODUCT YIELDS - A non-naturally occurring microbial organism includes a microbial organism having a reductive TCA or Wood-Ljungdahl pathway in which at least one exogenous nucleic acid encoding these pathway enzymes is expressed in a sufficient amount to enhance carbon flux through acetyl-CoA. A method for enhancing carbon flux through acetyl-CoA includes culturing theses non-naturally occurring microbial organisms under conditions and for a sufficient period of time to produce a product having acetyl-CoA as a building block. Another non-naturally occurring microbial organism includes at least one exogenous nucleic acid encoding an enzyme expressed in a sufficient amount to enhance the availability of reducing equivalents in the presence of carbon monoxide or hydrogen, thereby increasing the yield of redox-limited products via carbohydrate-based carbon feedstock. A method for enhancing the availability of reducing equivalents in the presence of carbon monoxide or hydrogen includes culturing this organism for a sufficient period of time to produce a product. | 08-18-2011 |
20110201090 | Yeast microorganisms with reduced by-product accumulation for improved production of fuels, chemicals, and amino acids - The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In various aspects of the invention, the recombinant microorganisms may further comprise one or more modifications resulting in the reduction or elimination of 3 keto-acid (e.g., acetolactate and 2-aceto-2-hydroxybutyrate) and/or aldehyde-derived by-products. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the | 08-18-2011 |
20110212507 | METHODS FOR INCREASING PRODUCT YIELDS - A non-naturally occurring microbial organism includes a microbial organism having a reductive TCA or Wood-Ljungdahl pathway in which at least one exogenous nucleic acid encoding these pathway enzymes is expressed in a sufficient amount to enhance carbon flux through acetyl-CoA. A method for enhancing carbon flux through acetyl-CoA includes culturing theses non-naturally occurring microbial organisms under conditions and for a sufficient period of time to produce a product having acetyl-CoA as a building block. Another non-naturally occurring microbial organism includes at least one exogenous nucleic acid encoding an enzyme expressed in a sufficient amount to enhance the availability of reducing equivalents in the presence of carbon monoxide or hydrogen, thereby increasing the yield of redox-limited products via carbohydrate-based carbon feedstock. A method for enhancing the availability of reducing equivalents in the presence of carbon monoxide or hydrogen includesculturing this organism for a sufficient period of time to produce a product. | 09-01-2011 |
20120070878 | Microporous Microfluidic Device - A micro fluidic apparatus includes (i) a first conduit; (ii) a second conduit; and (iii) a first interconnected microporous network in communication with the first and second conduits and configured to allow diffusion of gas between the first and second conduits. The microporous network comprises poly(dimethylsiloxane) (PDMS) and prevents flow of aqueous fluid between the first and second conduits through the microporous network. | 03-22-2012 |
20120107913 | MICROORGANISM CULTURE SHEET AND MANUFACTURING METHOD THEREFOR - A microorganism culture sheet is provided which can limit the use of a costly cultivation material to a necessary portion, which has simple production at the time of manufacture, and can be simply and stably used by a user. The microorganism culture sheet of the present invention is a microorganism culture sheet comprising a base sheet, a culture layer formed on top of the base sheet, and a cover sheet that covers the culture layer, and the culture layer is pattern-formed with an application liquid comprising a polyvinylpyrrolidone and at least on selected from the group consisting of a gelling agent, a nutrient component, a color indicator, a selective agent and a substrate. | 05-03-2012 |
20120202269 | GELATINOUS SUBSTANCE BASED GROWTH MEDIUM FILTRATION DEVICE AND METHOD - Growth medium filtration devices are provided which are particularly well adapted to sterilize gelatinous substance based growth mediums including agar, agarose and other polysaccharide derived growth mediums for use in agar plates and the like for culturing microorganisms. The devices may include one or more filtration units and at least one heat source for filtering the growth medium in a heated filtration process. Methods of filtering a growth medium, such as an agar growth medium, and methods of preparing a growth medium having low gelling point and lower molecular weight characteristics are also provided. | 08-09-2012 |
20120301948 | Novel method of acid hydrolysis of biomass and the recovery of sugars thereof by solvent extraction - The present invention provides for a method of hydrolyzing a cellulose, hemicellulose, or ligno-cellulose comprising: (a) contacting (i) an ionic liquid (IL) or ionic liquid-aqueous (ILA) phase comprising cellulose, hemicellulose, or ligno-cellulose, or a mixture thereof, and (ii) an acid, such that the cellulose, hemicellulose, or ligno-cellulose is hydrolyzed into sugar, and (b) optionally adding water to the IL or ILA phase wherein the proportion of water in the IL or ILA phase does not exceed about 60% by weight. The present invention also provides for a method of recovering a sugar comprising contacting an IL or ILA phase and an organic phase comprising an organic acid. | 11-29-2012 |
20120301949 | METHOD AND SYSTEM FOR PRODUCING HYDROGEN FROM CARBON-CONTAINING RAW MATERIALS - The invention refers to a process to produce H | 11-29-2012 |
20130011905 | INCUBATOR DEVICE AND METHOD OF OPERATING IT - A movable incubator facility comprises a culture chamber which is arranged for receiving at least one cell culture, a heating arrangement by means of which the temperature of the culture chamber can be adjusted, a gas feed arrangement by means of which at least one gas can be introduced into the culture chamber, and an energy storage arrangement which is disposed for supplying the heating arrangement and/or the gas feed arrangement with electrical energy. | 01-10-2013 |
20130224837 | INOCULATION TOOL AND METHOD OF USE THEREOF - The present invention describes disposable inoculation tools designed to fit into an appropriately sized test tube with the lid closed. A method that reduces the overall number of steps required to complete inoculation and can reduce repetitive motion injuries that might result from repetitive inoculation is also disclosed. | 08-29-2013 |
20140004596 | USE OF CARBONATES FOR BIOLOGICAL AND CHEMICAL SYNTHESIS | 01-02-2014 |
20140193883 | GAS EXHAUST FILTER DEVICE FOR A BIOREACTOR - A gas exhaust filter device for a bioreactor with reduced blockage by condensed liquid is disclosed, which comprises a housing with a filter medium, a gas inlet and a gas outlet and also further comprises a plurality of ribs extending from at least one inner wall of the housing in a region between the gas inlet and the filter medium. | 07-10-2014 |
20140295529 | COMPOSITIONS COMPRISING EICOSAPENTAENOIC ACID SUITABLE FOR HIGH PURIFICATION - The invention relates to a microbial biomass composition produced from a heterotrophic fermentation whose fatty acid profile exhibits an eicosapentaenoic acid (EPA) to arachidonic acid (ARA) ratio of about 11:1 or more, an EPA to total co-concentrating fatty acid ratio of about 8:1 or more, extract compositions, and methods of producing such compositions. | 10-02-2014 |
20140335597 | SINGLE-USE VERTICAL WHEEL BIOREACTORS - A pneumatic bioreactor includes a vessel containing a fluid to be mixed and at least one mixing device driven by gas pressure. A first embodiment includes a floating impeller that rises and falls in the fluid as gas bubbles carry it upward to the surface where the gas is then vented, permitting the impeller to sink in the fluid. The floating impeller may be tethered to a second impeller with a flexible member and pulley. The mixing speed is controlled with electromagnets in the vessel acting upon magnetic material in the impeller or its guides. In another embodiment, floating pistons mix the fluid, pushing it through a mixing plate with one or more apertures. In a third embodiment, the mixing device is a rotating drum with bubble-catching blades and rotating mixing plates with apertures. The top of the vessel for these mixers may include a closed top and sterile filters. | 11-13-2014 |
20140377843 | AUTOMATED MICROBIOLOGY LABORATORY INSTRUMENT AND SYSTEM USES THEREOF - The present application discloses an automated laboratory system comprising of an instrument and an accompanied system to prepare biological culture plates specifically microbiological culture plates for sample inoculation and a process of sample inoculation. Further, the application discloses various modules of a system required to run the different units of the instrument. | 12-25-2014 |
20150125930 | COLLAPSIBLE BAG WITH FLEXIBLE VORTEX BREAKER - A generally cylindrical collapsible mixing vessel, comprising: a) a flexible plastic film side wall, a top wall and a bottom wall, wherein both the top wall and the bottom wall are attached to the side wall and the side, top and bottom walls define an inner volume of the vessel; b) an agitator located in the inner volume and; c) at least one vortex breaker made from flexible plastic film, located in the inner volume and attached to the bottom wall and/or the side wall via string elements, wherein said vortex breaker extends along the side wall and inwards in a generally radial direction. | 05-07-2015 |
20150125931 | METHOD FOR PROCESSING OF STABLE EMULSIONS FROM WHOLE-CELL BIOTRANSFORMATIONS BY MEANS OF PHASE INVERSION - A method processes a stable emulsion having components from whole-cell biotransformations such as cells, soluble cell components, organic solvents and/or water. In this connection, the emulsion, which is stable after the biotransformation, is mixed with further parts of organic phase, and subsequently the mixture is continuously stirred until a catastrophic phase inversion of the emulsion takes place while mixing; subsequently, this phase-inverted mixture is transferred to a settling container, where the phases of the emulsion separate from one another and can be separated from one another. | 05-07-2015 |
20150299642 | CELL CULTURE APPARATUS AND METHOD OF USING THE SAME - A cell culture apparatus comprises at least one storage space, at least one barrier, a working space, a sterilization space, and a control space. The at least one storage space comprises a container shelf, an upright track, a rotatable holder, and a light tube. The working space comprises a filling station and an inspecting station. The filling station comprises a first delivering device, an open-close device, and a filling mechanism. The inspecting station comprises a first inspecting mechanism and a second delivering device. Also provided is a method of using the cell culture apparatus including steps of filling, inspecting, or collecting cell cultures, therefore, the cell culture apparatus performs multiple cell culture processes automatically. | 10-22-2015 |
20150353879 | OMNI-FUNCTIONAL HIGH-EFFICIENT SOLID-STATE FERMENTATION METHOD FOR EDIBLE AND MEDICINAL MICROORGANISMS - A solid-state fermentation method is provided. The method is provided for edible and medicinal microorganisms. A commensurate device is used for processing sterilization, inoculation, cultivation, drying, and collection. Cultivation substrates are filled in cultivation plates and placed on trays of a movable layer rack in a reaction fermenter for fermentation. Inner pipes provide inoculation, fluid nutrient, and air for fermentation of microorganisms. The reaction fermenter is accompanied with a dry circulation unit and a production collection unit for drying and collection. The solid-state fermentation processes are thus effectively integrated without the need of transferring fermented products between stations, which largely reduces contamination rate. Even more, there is no need to purchase automatic production equipments of high mechanical technologies. Thus, the present invention reduces labor requirement, saves time and energy, deducts cost of automatic equipments, achieves low contamination rate, and processes automatic mass production even without automatic production equipments. | 12-10-2015 |
20160009784 | Chimeric Receptors with 4-1BB Stimulatory Signaling Domain | 01-14-2016 |
20160040114 | DEVICES, SYSTEMS AND METHODS FOR AUTOMATED TRANSFER OF A SAMPLE - A coupling device configured to form a sample access assembly is provided. The sample access assembly is configured to house a sample. The coupling device includes a heating component and a separating component. Further, the separating component is configured to separate portions of first and second containers that form first and second compartments of the sample access assembly. Moreover, the heating component is configured to heat at least a portion of the sample. | 02-11-2016 |
20160122697 | Devices and Methods for Creating and Testing Microbes and Biofilms - Systems and methods for growing microbes and biofilms on a hydrogel in a controlled environment. The system can have a cup, and a liner with the liner inserted into the cup and a hydrogel inserted into the liner. The cup, liner, and hydrogel assembly can be placed into a containment tray. The hydrogel can be sterilized before being placed into the containment tray. A lid can seal the cup, liner, and hydrogel into the containment tray. A lid can have inoculations ports, or can be made out of a self-sealable material keeping the inside environment sterilized and free of contaminants. The hydrogel can be inoculated with microbes through the inoculations ports, and incubated for a period of time at a set temperature to allow the microbes, and biofilms time to grow. After being grown the microbes and biofilms can be separated from each other allowing for both microbes and biofilm to be separately tested. | 05-05-2016 |
20160177253 | METHOD AND SYSTEM FOR PREPARATION OF SUBSTRATE FOR USE IN ANAEROBIC DIGESTION OF ORGANIC WASTE | 06-23-2016 |
20160177255 | LABYRINTHULOMYCETE STRAINS FOR PRODUCING DOCOSAHEXAENOIC ACID | 06-23-2016 |