Class / Patent application number | Description | Number of patent applications / Date published |
435259000 | Lysis of micro-organism | 11 |
20080248554 | DEVICES AND METHODS FOR SELECTIVELY LYSING CELLS - A device for generating microbubbles in a gas and liquid mixture and injection device, the device comprising: a housing defining a mixing chamber; means for mixing solution contained in the mixing chamber to generate microbubbles in the solution; a needle array removably attached to the housing and in fluid connection with the mixing chamber, the needle array including at least one needle; and a machine readable identifier on the needle array. | 10-09-2008 |
20090233348 | METHOD FOR ISOLATING PROTEINS FROM PRODUCTION CELLS - A method for the disruption of biological cells by means of a homogenizer device which | 09-17-2009 |
20100055766 | MICROFLUIDIC CARTRIDGE FOR SEPARATING TARGET MOLECULES, AND SEPARATOR AND METHOD OF SEPARATING TARGET MOLECULES USING SAME - A microfluidic cartridge includes a capture portion capturing target material on surfaces of nonmagnetic particles; and a separating portion separating target molecules from the target material captured on the surfaces of the particles. The microfluidic cartridge is mounted on an adaptor that is rotated by a rotating unit in order to separate a fluid including the target molecules from the particles through centrifugal force. | 03-04-2010 |
20100317088 | Systems and Methods for Extracting Lipids from Wet Algal Biomass - Presented herein are exemplary systems and methods for extracting lipids from a wet algal biomass. An exemplary method comprises lysing a wet algal biomass with an insoluble granular lysing agent to create a lysate, creating a lipid-rich phase in the lysate, and separating the lipid-rich phase from the lysate. An exemplary system comprises a lysing station for creating a lysate from a wet algal biomass and a separation station for creating and separating a lipid-rich phase from the lysate. According to further exemplary systems and methods, ultrasound may be used in place of or in addition to a lysing agent to lyse the wet algal biomass. | 12-16-2010 |
20110189759 | METHOD AND DEVICE FOR THE DIGETSION OF BIOLOGICAL CELLS - The invention relates to a method and a device for the digestion of biological cells. Digestion of cells is understood as breaking up cells so that hereditary information can be removed. Using the present invention, nucleic acids are to be able to be removed from cells in particular. The nucleic acids include RNA and DNA. According to the invention, cells are digested in a vessel which can be connected to a line and can thus be part of an overall device. Liquid can drain out of the container or can be pumped into the container via the line, for example. The typical means for performing a mechanical digestion are located in the vessel, that is, in particular beads and a buffer solution. In contrast to the prior art, however, the vessel is not shaken, that is, subjected to vibrations. Instead, it is stirred with the aid of a magnetic stirrer. Strong vibrations are thus avoided. A vessel for performing digestion of cells can therefore be integrated without problems in an overall device. | 08-04-2011 |
20140141497 | MICROFLUIDIC CHEMOSTAT - A chemostat is described that includes a growth chamber having a plurality of compartments. Each of the compartments may be fluidly isolated from the rest of the growth chamber by one or more actuatable valves. The chemostat may also include a nutrient supply-line to supply growth medium to the growth chamber, and an output port to remove fluids from the growth chamber. Also, a method of preventing biofilm formation in a growth chamber of a chemostat is described. The method may include the steps of adding a lysis agent to a isolated portion of the growth chamber, and reuniting the isolated portion with the rest of the growth chamber. | 05-22-2014 |
20140242678 | APPARATUS AND METHOD FOR A LYSIS OF A SAMPLE, IN PARTICULAR FOR AN AUTOMATED AND/OR CONTROLLED LYSIS OF A SAMPLE - The present invention provides an apparatus and a method for a lysis procedure, in particular for an automated and/or controlled lysis procedure of a sample, in particular a biological sample. The apparatus comprises at least one rotation disc ( | 08-28-2014 |
20140342439 | PORTABLE SAMPLE DISRUPTOR APPARATUS, KITS, AND METHODS - Apparatuses, kits, and methods for portable sample disruption (e.g., for encouraging cell lysis). | 11-20-2014 |
20150315135 | Sulphated Chelating Agent - This invention refers to a series of substances according to formula (I): and its synthesis process. The subtances according to formula I above, known as sulphated chelating agents have the ability to enlarge/loosen simple cell membranes or common organic membranes. Furthermore, these subtances have the potential as biocides raw material, with very low toxicity to mammals. These features make the substances of this invention become very useful on many applications. | 11-05-2015 |
20150368634 | METHOD AND APPARATUS FOR EXTRACTING DNA FROM A BIOLOGICAL SAMPLE - A method of extracting DNA from a biological sample includes the steps of freezing a biological sample; mechanically breaking down the sample to produce a processed sample; mixing the processed sample with a lysis solution; and cycling the mixture through a series of pressure fluctuations to produce a resulting lysate. The method may further include the steps of exposing the lysate to a material that binds to DNA present in the sample and collecting the DNA from the sample using an elution solution. An apparatus for practicing the method includes a first segment for mechanically breaking down the sample; a second segment for pressurizing a mixture of the processed sample and lysis solution to produce a lysate; and wherein the first segment is fluidly coupled to the second segment. The apparatus may also include a third segment in which the lysate is exposed to the binding material. | 12-24-2015 |
20160186127 | CAPTURE AND ELUTION OF BIO-ANALYTES VIA BEADS THAT ARE USED TO DISRUPT SPECIMENS - Lysing may include agitating a specimen in a chamber along with a medium that includes a particulate lysing material that has an affinity for a biological material. Lysing material may include beads or other material which may be coated that facilitates binding. The medium may include a fluid with a high salt or low pH level. The biological material may be eluted by lowering a concentration of salt or increasing a pH level. Lysing materials with two or more different affinities may be employed. Heating may be used. Lysing may be performed in a flow through apparatus. | 06-30-2016 |