| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 435227000 | Acting on carbon to nitrogen bond other than peptide bond (3.5) | 22 |
| 20090111162 | SEQUESTRATION OF FORMALDEHYDE TO STABILIZE NITRILASE SPECIFIC ACTIVITY WHEN CONVERTING GLYCOLONITRILE TO GLYCOLIC ACID - A process is provided to improve the specific activity of an enzyme catalyst having nitrilase activity when converting glycolonitrile to glycolic acid under aqueous reaction conditions. Inclusion of an effective amount of at least one amine protectant improves the specific activity and catalytic productivity of the enzyme catalyst. | 04-30-2009 |
| 20090181445 | Crystallization and Structure of a Plant Peptide Deformylase - This invention relates to the crystal structure of a plant peptide deformylase polypeptide and methods of using the structure to design compounds that modulate the activity of the polypeptide. | 07-16-2009 |
| 20090269831 | Modified cytosine deaminases - The document provides modified cytosine deaminases with increased solubility and high levels of DNA cytosine deaminase activity. | 10-29-2009 |
| 20090305384 | Class II Human Histone Deacetylases, and Uses Related Thereto - The invention provides histone deacetylase class II nucleic acids and polypeptides, methods and reagents for their use, and related compounds including small molecule libraries containing class II histone deacetylase inhibitors. | 12-10-2009 |
| 20100009426 | Nitrilases, Nucleic Acids Encoding Them and Methods for Making and Using Them - The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature. | 01-14-2010 |
| 20100086986 | Nitrilases and Methods for Making and Using Them - The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature. | 04-08-2010 |
| 20100136656 | IMMOBILIZED MICROBIAL NITRILASE FOR PRODUCTION OF GLYCOLIC ACID - The present invention is directed to a process for improving the specific activity of a dehydrated enzyme catalyst having nitrilase activity for hydrolysis of glycolonitrile to glycolic acid upon rehydration. In particular, a process is provided comprising pretreating an enzyme catalyst having nitrilase activity with glutaraldehyde, immobilizing the gutaraldehyde-preteated enzyme catalyst and chemically cross-linking the enzyme catalyst prior to dehydration. Upon rehydration, the enzyme catalyst exhibits improved specific nitrilase activity as compared to enzyme catalysts having nitrilase activity that are dehydrated and rehydrated without the processing described herein. | 06-03-2010 |
| 20100184189 | PROTEIN FOR THE CHEMOENZYMATIC PRODUCTION OF L-THREO-HYDROXYASPARTATE - A simple mutant of the natural asparagine oxygenase comprises at least the amino acids 13 to 318 of the natural asparagine oxygenase AsnO. In this protein according to the present invention, comprising at least the amino acids 13-318 of AsnO D241N, the amino acid residue at position 241 of the natural asparagine oxygenase AsnO is exchanged from aspartate (D) to asparagine (N). The protein according to the present invention, comprising at least the amino acids 13-318 of AsnO D241N, is produced by means of a directed mutagenesis from the AsnO wild type, cloning of this expression plasmid into a vector, transformation of the vector plasmid construction into a host organism and expression of the recombinant protein. The protein according to the present invention is suitable for the chemoenzymatic and enantioselective production of L-threo-hydroxyaspartate from L-aspartate. The protein is substrate-specific and converts quantitatively L-aspartate into L-threo-hydroxyaspartate. | 07-22-2010 |
| 20100216214 | Nitrilases, Nucleic Acids Encoding Them and Methods for Making and Using Them - The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature. | 08-26-2010 |
| 20110104787 | Fusion Peptides That Bind to and Modify Target Nucleic Acid Sequences - Novel methods and compositions for altering target nucleic acid (e.g., DNA e.g., genomic DNA) sequences are provided. Fusion proteins including one or more DNA binding domains and one or more DNA modifying domains are provided. Isolated polynucleotides encoding fusion proteins including one or more DNA binding domains and one or more DNA modifying domains are provided. | 05-05-2011 |
| 20140186924 | METHODS FOR TRANSFORMING TARWI AND FOR PRODUCING MOLECULAR FARMING PRODUCTS IN TRANSGENIC TARWI SEED - The present disclosure describes reproducible methods for the | 07-03-2014 |
| 20150125928 | NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature. | 05-07-2015 |
| 435228000 | Acting on a linear amide linkage in linear amide | 7 |
| 20090061500 | Novel protein-deamidating enzyme, microorganism producing the same, gene encoding the same, production process therefor, and use thereof - A method for the production of an enzyme, which comprises culturing in a medium a strain that belongs to a bacterium classified into Cytophagales or Actinomycetes, or a new bacterium | 03-05-2009 |
| 20110236955 | ARYLACYLAMIDASE GENE AND METHOD OF USING THE SAME - The present invention provides an efficient method of producing an arylacylamidase. In an aspect, the present invention provides (a) a DNA comprising the base sequence shown in the sequence listing under SEQ ID NO:1, or (b) a DNA capable of hybridizing, under stringent conditions, with a DNA comprising the base sequence complementary to the base sequence shown in the sequence listing under SEQ ID NO:1 and coding for a polypeptide having arylacylamidase activity. In another aspect, the invention provides a polypeptide encoded by the DNA mentioned above and having arylacylamidase activity, a vector containing the DNA mentioned above, a transformant which is transformed using the DNA or the vector mentioned above, and a method for producing an arylacylamidase which comprises cultivating the transformant mentioned above and obtaining the arylacylamidase from the culture medium. | 09-29-2011 |
| 20120184018 | Genetically Programmed Expression of Selectively Sulfated Proteins in Eubacteria - The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the unnatural amino acid sulfotyrosine into proteins produced in eubacterial host cells such as | 07-19-2012 |
| 20160032268 | UREASE PURIFICATION FROM JACK BEANS OR OTHER ORGANISMS - A method for the extraction and purification of urease from jack beans or other natural sources of urease. The method provides an efficient way to obtain purified urease from natural sources. The method can include defatting the natural sources of urease, extracting the urease from impurities, and further purification of the extracted urease. | 02-04-2016 |
| 435229000 | Asparaginase | 3 |
| 20090047725 | Method for Increasing Asparaginase Activity in a Solution - A stable asparaginase solution is disclosed. In one aspect, drinking water is treated to reduce the level of chlorine to enhance the residual enzyme activity of asparaginase. The treatment can occur by removing chlorine constituents or by supplying additives that reduces the level of chlorine. Additives can include reducing agents and chlorine scavengers. Removal technologies can include use of activated carbon, ion exchange, and air stripping. | 02-19-2009 |
| 20100273236 | RECOMBINANT HOST FOR PRODUCING L-ASPARAGINASE II - The invention provides a recombinant | 10-28-2010 |
| 20130023029 | NOVEL ASPARAGINASES AND USES THEREOF - The present invention relates to an asparaginase having the width of the pH activity profile which is at least 3.5. Furthermore the invention relates to newly identified asparaginase polypeptide according to any one of SEQ ID NO: 2 or SEQ ID NO: 4 and to variants thereof and to polynucleotide sequences that encode such novel asparaginase variants. Furthermore the invention relates to the use of these novel asparaginase variants in industrial processes. | 01-24-2013 |
| 435231000 | Acting on amide linkage in cyclic amides (e.g., penicillinase, etc.) (3.5.2) | 3 |
| 20140127785 | MODIFIED BETA-LACTAMASES AND METHODS AND USES RELATED THERETO - The present invention relates to pharmaceuticals and modified beta-lactamases. Specifically, the invention relates to novel recombinant beta-lactamases and pharmaceutical compositions comprising the beta-lactamases. Also, the present invention relates to methods for modifying a beta-lactamase, producing the beta-lactamase and treating or preventing beta-lactam antibiotic induced adverse effects. Furthermore, the present invention relates to the beta-lactamase for use as a medicament and to the use of the beta-lactamase in the manufacture of a medicament for treating or preventing beta-lactam antibiotics induced adverse effects. | 05-08-2014 |
| 20160168557 | MODIFIED BETA-LACTAMASES AND METHODS AND USES RELATED THERETO | 06-16-2016 |
| 20180023072 | BETA-LACTAMASES WITH IMPROVED PROPERTIES FOR THERAPY | 01-25-2018 |
