| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 435700310 | Fungi (e.g., yeast, mold, etc.) | 26 |
| 20080268475 | YEAST CELLS EXPRESSING MODIFIED G PROTEINS AND METHODS OF USE THEREFOR - The present invention pertains to novel yeast cells which are useful for the expression of heterologous G protein coupled receptors. The yeast cells of the present invention can be used in screening assays which can be used to screen for modulators of G protein coupled receptors. Specifically, the invention provides novel yeast cells which express a heterologous G protein coupled receptor and mutant and/or chimeric G protein subunit molecules which serve to functionally integrate the heterologous into the pheromone signaling pathway of the yeast cell. The invention also provides for the expression of heterologous G protein coupled receptors which are functionally integrated into the yeast cell membrane using a yeast α factor leader sequence. Drug discovery assays using the subject yeast cells are also provided. | 10-30-2008 |
| 20080293079 | Chip for Diagnosing the Presence of Candida - The present invention concerns means and methods of detection of | 11-27-2008 |
| 20080311595 | Rapid fungal detection assay and product - The present invention relates to the use of an assay and product for rapid detection of fungi in a variety of samples suspected of containing fungi, particularly swab samples from the human vaginal area, but also in other environments such as in food and feeds. The product of the invention is suitable for use in a variety of different environments, including in clinical settings, at the point of care, and by patients themselves (bedside kit). | 12-18-2008 |
| 20090111129 | Methods and Kits for Detecting Fungal Infection - Methods and kits which utilize a conjugate, preferably an adduct, of ergosterol for determining the presence or level of a broad spectrum of ergosterol-containing organisms (e.g., fungi) in various substrates are disclosed. These methods and kits can be used to accurately and efficiently diagnose a subject having a fungal infection, particularly invasive fungal infection, and to accurately and efficiently detect the presence of fungi and other ergosterol-containing organisms in other substrates. Antibodies and other compounds (e.g., molecularly imprinted polymers) that are capable of selectively binding to ergosterol or to an ergosterol-containing conjugate and methods of producing same are also disclosed. | 04-30-2009 |
| 20090246806 | COCCIDIOIDES ANTIGEN IMMUNOASSAY - The present disclosure relates to methods for detecting a | 10-01-2009 |
| 20090305312 | In Vitro Diagnostic Method and Kit for an Aspergillus Infection - The present invention relates to a method for the in vitro diagnosis of an | 12-10-2009 |
| 20090305313 | Diagnosis of candidiasis and candidemia or invasive candida infection - The use of an antibody to a | 12-10-2009 |
| 20100099122 | FERRIC REDUCTASE ACTIVITY OF HISTOPLASMA CAPSULATUM Y-GLUTAMYLTRANSFERASE - A novel gamma-glutamyltransferase gene and its encoded protein isolated from the fungus | 04-22-2010 |
| 20100105081 | DETECTING FUNGI IN HUMAN SAMPLES - Methods and materials involved in detecting fungi in human samples are provided herein. | 04-29-2010 |
| 20100129835 | Methods for Selecting Improved Strains - The present invention relates to a system for improving a strain of filamentous fungus that is useful in producing an enzyme of interest such as a cellulase. The invention involves generating genetic diversity in a strain of fungal cells, subjecting the population of cells to selection, and isolating the cells that overproduce the enzyme. The selection techniques involve culturing the population of cells in purified cellulose and/or at an elevated temperature that is adverse to production of the enzyme. | 05-27-2010 |
| 20100196932 | Yeast Reporter System - Cell-based screens for compounds that inhibit the accumulation of amyloids are described. For example, the herein described screens may be used to assay the formation, or inhibition, of pre-amyloid or amyloid aggregates and/or oligomers. Agents have been identified that interfere with, or inhibit, the oligomerization of the major component of amyloid plaques; a | 08-05-2010 |
| 20100227338 | Method and Apparatus for Rapid Detection and Identification of Live Microorganisms Immobilized On Permeable Membrane by Antibodies - An apparatus and method is provided for the rapid detection, identification and/or enumeration of one or more live target microorganisms growing on solid nutrient media or filtration membrane. Microcolonies or colonies attach to a porous transfer permeable membrane loaded with immobilized antibodies specific for target microorganisms. Non-specific cells are washed out of the permeable membrane and the membrane then is placed on a container containing a chromogenic and/or a fluorogenic substrate and incubated to allow coloration and subsequent identification and enumeration of color spots of targeted microorganisms and patterns of microcolonies or colonies. | 09-09-2010 |
| 20100240074 | Set of Yeast Cells, Method of Identifying Target Candidate Molecule, Method of Analyzing Action Mechanism and Screening Method - Provided is a set of yeast gene knockout strains whose drug sensitivity is significantly improved. A set of yeast cells of the invention is a set of yeast cells comprising two or more types of yeast cells, wherein at least one mutually different gene has been deleted or mutated in each of the two or more types of yeast cells, and all of the two or more types of yeast cells are drug hypersensitive yeast cells in which the expression of at least one drug sensitivity-related gene is regulated. | 09-23-2010 |
| 20100285505 | Device and Method for Detecting a Substance by Means of Particle Plasmon Resonance (PPR) or Particle-Mediated Fluorescence Based on Cell Surface Polarizations - The invention relates to devices and methods for detecting a substance by cell surface polarizations and the detection thereof by means of PPR or particle-mediated fluorescence. The device for detecting a substance by cell surface polarization according to the invention has cells, wherein a gene the expression of which leads to the polarized presentation of a protein on the surface of the cell is placed under the control of a promotor which can be regulated by the substance to be detected, nanoparticles which are functionalized with a molecule which can bind specifically to the surface-exposed protein, and at least one optical measurement device, such that an accumulation of the nanoparticles on the surface of the cells can be detected by particle plasmon resonance or particle-mediated fluorescence. | 11-11-2010 |
| 20110053187 | SILICA-BASED MATERIAL FOR DETECTION AND ISOLATION OF CHITIN AND CHITIN-CONTAINING MICROORGANISMS - The subject invention provides silica-based material that has high affinity to chitin, chitin derivatives and chitin-containing microorganisms at an acidic pH. In an embodiment, the silica-based material surface comprises glass. Also provided are methods for preparing the subject silica-based chitin-binding material. In addition, the subject invention provides rapid, specific, sensitive, accurate and convenient methods for detection, isolation and purification of chitin, chitin derivatives and chitin-containing microorganisms. | 03-03-2011 |
| 20110223620 | Method of detecting microorganisms and microorganism detecting apparatus - It is possible to determine the presence of bacteria in a sample solution in a shorter period of time without changing a conventional incubating method. Bacteria in a sample solution are incubated in, for example, a sterilized agar medium | 09-15-2011 |
| 20110281283 | YEAST CELL WALL COMPONENTS AND DETECTION THEREOF - The present invention relates to animal feed additives and detection thereof in feed products. Additionally, the present invention relates to yeast cell wall components, their methods of isolation, and compositions and methods for the immunological detection thereof. | 11-17-2011 |
| 20120058494 | Quenched Dendrimeric Dyes for Florescence Detection - The present invention presents designs for high extinction quenched “dyedrons” that can be activated by conversion of a single acceptor/quencher in the molecular assembly to a fluorescent state. The quencher is activated by noncovalent binding to a unique complementary expressible fluorogen activating peptide (FAP). In this way, the quencher serves as the homogeneous switch, receiving energy efficiently from each of the donor molecules of the dendronic antenna, and releasing it as fluorescence only when activated by binding. The sum of the extinction of the multiple dyes on the antenna will provide dramatic enhancements in the effective brightness of the probe in standard imaging systems. This approach provides a set of probes with exceptional brightness, specifically targeted to an expressed tag that activates the fluorescence of the dyedron. | 03-08-2012 |
| 20120070850 | Method for detecting microorganisms and microorganism detecting apparatus - It is possible to determine the presence of bacteria in a sample solution in a shorter period of time without changing a conventional incubating method. Bacteria in a sample solution are incubated in, for example, a sterilized agar medium | 03-22-2012 |
| 20120282635 | SELF-CALIBRATING GRADIENT DILUTION IN A CONSTITUTENT ASSAY AND GRADIENT DILUTION APPARATUS PERFORMED IN A THIN FILM SAMPLE - A method and apparatus for measuring antibody titers in a thin film sample in an automated system which does not require multiple dilutions. The system provides a simple method for creating an in-situ dilution within a sample analysis chamber without the use of any precision fluid-handling components, and further, to use the same principles to provide a wide range of sample dilutions within the chamber so as to obviate the need for additional dilution steps when dealing with samples possibly containing wide ranges of analyte concentrations. | 11-08-2012 |
| 20130011862 | RAPID PROCESS FOR DETECTION OF MICROORGANISMS WITH MAGNETIC PARTICLES - The present invention relates to processes for the rapid detection, semi-quantification and quantification of live microorganisms in solutions or suspensions using immunomagnetic particles, without requiring pre-enrichment through culture of the microorganism. The invention also relates to kits for carrying out said processes and to the quantification of the microorganisms detected by means of automated biosensor equipment. | 01-10-2013 |
| 20130309693 | POLYPEPTIDES FOR MICROBIAL DETECTION - Polypeptides which can be activated to cause the formation of pores in a lipid membrane are disclosed. Also disclosed are polypeptide compositions for the detection of target microorganisms and methods of using said compositions. | 11-21-2013 |
| 20140004538 | METHOD FOR DIAGNOSING INVASIVE CANDIDA INFECTIONS | 01-02-2014 |
| 20140178902 | METHOD FOR DETECTING INFECTIONS - The present invention relates to a method for detecting infections caused by or associated with siderophore-secreting microorganisms and kits and components used therein for carrying out the method. In one aspect the invention relates to a method for detecting siderophores and/or detecting infections caused by or associated with siderophore-secreting microorganisms in a biological sample of a subject, the method comprising providing a solid support having either bound siderophore or a conjugate thereof, or bound anti-siderophore antibody; reacting the bound siderophore or a conjugate thereof, with an anti-siderophore antibody, and a biological sample of a subject; or reacting the bound anti-siderophore antibody with a siderophore or conjugate thereof, and a biological sample of a subject; and detecting and/or quantifying the presence of the siderophore in the biological sample. | 06-26-2014 |
| 20150072358 | HAND-HELD MEASURING INSTRUMENT AND PROCEDURE FOR THE DETECTION OF MOLD ATTACK IN INTERIOR SPACES - A hand-held measuring instrument is used for detecting hidden mold damage in interior spaces. The measuring instrument includes at least one collection unit configured to intake at least of one interior space sample, at least one buffer unit, at least one immunological test unit, an evaluation unit and a control panel. The at least one buffer unit has a first compartment and a second compartment. | 03-12-2015 |
| 20150132777 | NON-HEATING DETECTION METHOD FOR DERMATOPHYTE - The present invention provides a method of detecting dermatophyte, which does not require a complicated operation such as an enzyme treatment and a heat treatment. | 05-14-2015 |
