Class / Patent application number | Description | Number of patent applications / Date published |
427200260 | For mineralized body part (e.g., bone, tooth, crown, hip) | 45 |
20080206443 | ENHANCED BONDING LAYERS ON TITANIUM MATERIALS - The present invention provides a dense-coverage, adherent phosphorous-based coating on the native oxide surface of a material. Disclosed phosphorous-based coatings include phosphate and organo-phosphonate coatings. The present invention also provides further derivatization of the phosphorous-based coatings to yield dense surface coverage of chemically reactive coatings and osteoblast adhesion-promoting and proliferation-promoting coatings on the native oxide surface of a titanium material. | 08-28-2008 |
20080292779 | COATING OF IMPLANTS WITH HYALURONIC ACID SOLUTION - A method for fabricating and/or coating an implant or other structure to be inserted into bone or osseous tissue, including dental implants, is described in which the surface of the implant is treated with a hyaluronic acid solution to form a thin film conformal coating of the hyaluronic solution over the surface of the implant. The surface of the implant may be roughened and cleaned prior to treating the surface with the hyaluronic solution. After the coating is formed, the implant may be sterilized. | 11-27-2008 |
20090022878 | METHOD TO IMPREGNATE A POROUS BONE REPLACEMENT MATERIAL - A method to impregnate a porous bone replacement material ( | 01-22-2009 |
20090176006 | BIOMIMETIC MATERIALS COMPRISING POLYHEDRAL OLIGOMERIC SILSESQUIOXANES - Nanostructured chemicals such as polyhedral oligomeric silsesquioxanes, polyhedral oligomeric silicates, and polyhedral oligomeric metallasesquioxanes are attached to living and nonliving systems as biomaterials to provide a nanoscopic topology that favors biomimetic function and cellular modulation. The resulting surface is nanoscopically thin, nanoscopically dispersed, provides systematic chemistry, surface area, surface volume, surface topology, and is essentially free of impurities, and has controllable properties through selection of composition, R groups, nanostructure size and topology. Highly shape specific and chemically tailorable nanostructured molecules are sized to biological material dimensions and are compatible with all sterilization methods. | 07-09-2009 |
20100151114 | IN-LINE TREATMENT OF YARN PRIOR TO CREATING A FABRIC - A woven orthopedic implant for cartilage replacement having layered functionality and a method of forming the same. The woven orthopedic implant may include bottom layer of fibers that promotes anchoring to bone, and intermediate layer of fibers that promotes soft tissue attachment, and a top layer of fibers that promotes lubrication. The method may involve treating the surfaces of fibers before weaving the fibers together. | 06-17-2010 |
20100247738 | CURABLE ZIRCONIA ADHESIVE COMPOSITIONS FOR DENTAL RESTORATIONS - The present application relates to a polymerizable dental adhesive system formulated for effective and durable bonding of zirconia based materials and restorations to dental resins and dental surfaces. According to one embodiment, a polymerizable dental adhesive system comprises a first acidic monomer comprising an ethylenically unsaturated polymerizable group or moiety of the general formula CH | 09-30-2010 |
20100260924 | DIGITALLY-PAINTED DENTAL ARTICLES - A digital painting process provides computer-controlled finishing of dental articles. The process can selectively apply different materials over portions of a dental article in one or more layers to achieve a multi-chromatic finish having a variety of colors, finishes, and surface properties that closely match the appearance and function of human dentition. | 10-14-2010 |
20100291287 | POLYMERIC PLATE BENDABLE WITHOUT THERMAL ENERGY AND METHODS OF MANUFACTURE - An implantable plate for providing support to a bone of a subject when affixed thereto includes a polymeric body of a biocompatible polymer having a desired amount of polymer molecule orientation in a first direction so that the plate can be bent to conform with a contour of the bone of the subject. The polymeric body includes a top surface, a bottom surface, and at least one fastener portion. The fastener portion includes a recess and a fastener hold that is configured for receiving a fastener when affixed to the bone of the subject. A method of manufacturing the implantable plate includes: (1) injection molding a biocompatible polymeric composition into a polymeric body within an injection mold; (2) removing the polymeric body from the injection mold; and (3) forming at least one fastener hole within polymeric body. | 11-18-2010 |
20110033609 | Methods and Apparatus for Making Coatings Using Ultrasonic Spray Deposition - Ultrasonic spray deposition (USD) used to deposit a base layer on the substrate, followed by chemical vapor infiltration (CVI) to introduce a binder phase that creates a composite coating with good adherence of the binder to the initial phase particles and adherence of the composite coating to the substrate, is disclosed. We have used this process to create coatings consisting of cubic boron nitride (cBN), deposited using USD, and titanium nitride (TiN) applied using CVI in various embodiments. This process can be used with many materials not usable with other processes, including nitrides, carbides, carbonitrides, borides, oxides, sulphides and silicides. In addition, other binding or post-deposition treatment processes can be applied as alternatives to CVI, depending on the substrate, the coating materials, and the application requirements of the coating. Coatings can be applied to a variety of substrates including those with complex geometries. The application also describes apparatus or equipment designs used to perform ultrasonic spray deposition. | 02-10-2011 |
20110039014 | COMPOSITE PROSTHETIC BEARING HAVING A CROSSLINKED ARTICULATING SURFACE AND METHOD FOR MAKING THE SAME - An implantable prosthetic bearing is constructed of a composite material having a first layer and second layer. The first layer has an articulating surface defined therein, whereas the second layer has a engaging surface defined therein for engaging either another prosthetic component or the bone itself. The first layer of the implantable prosthetic bearing is constructed of crosslinked polymer such as Ultra-High Molecular Weight Polyethylene, whereas the second layer of the implantable prosthetic bearing is constructed of polymer such as Ultra-High Molecular Weight Polyethylene that is either non-crosslinked or crosslinked to a lesser degree than the first layer. In such a manner, the first layer possesses mechanical properties which are advantageous in regard to the articulating surface (e.g., enhanced wear and oxidation resistance), whereas the second layer possesses mechanical properties which are advantageous in regard to the engaging surface (e.g., high ductility, toughness, and creep resistance). A method of making a prosthetic bearing is also disclosed. | 02-17-2011 |
20110123705 | COHESIVE OSTEOGENIC PUTTY AND MATERIALS THEREFOR - Described is an implantable medical material comprising a malleable, cohesive, shape-retaining putty including mineral particles, insoluble collagen fibers and soluble collagen. The medical material can be used in conjunction with biologically active factors such as osteogenic proteins to treat bone or other tissue defects in patients. | 05-26-2011 |
20110143015 | PRIMER COMPOSITION FOR METAL OXIDE CERAMICS - [Problems] A primer used for pre-treating the surfaces of a prosthetic, which exhibits a large adhering force at the time of adhering a prosthetic of metal oxide ceramics to an object to be joined by using an adhesive such as a dental cement, the large adhering force being maintained for extended periods of time even in a severe environment such as in an oral cavity. | 06-16-2011 |
20110318476 | POROUS AND NONPOROUS MATERIALS FOR TISSUE GRAFTING AND REPAIR - Implants having improved mechanical properties and/or degradation profiles, kits including such implants, and methods of producing and using the same. | 12-29-2011 |
20120009327 | Method and Device for Coating of a Medical Implant - The invention relates to a method for coating of a medical implant that can be used to apply a calcium salt to the surface of a medical implant easily and without expensive coating equipment and little expenditure of time. | 01-12-2012 |
20120164311 | COATING METHOD AND COATING DEVICE - A device for coating at least regions of a medical implant including a powder having at least one pharmaceutically active substance or one bone growth-promoting substance such that the powder can be transferred to the medical implant when the medical implant is contacted. | 06-28-2012 |
20120164312 | COATING METHOD AND COATING DEVICE - A method for coating at least regions of a medical implant includes providing a medical implant having a surface to be coated, and immersing the surface of the medical implant into a liquid including at least one pharmaceutically active substance, whereby the liquid is transferred to the surface of the medical implant due to the immersing. The method also includes pulling the surface of the medical implant out of the liquid, whereby part of the liquid remains adhering to the surface of the medical implant. | 06-28-2012 |
20120213911 | METHOD FOR THE REALIZATION OF BIOLOGICALLY COMPATIBLE PROSTHESIS - Method for the realization of a biologically compatible prosthesis component including the steps of having at least two materials with different physical/chemical features, defining in forming means the component as a composition of at least two volumes of at least two materials, sintering the component in the forming means and at a preset sintering temperature (T | 08-23-2012 |
20120269956 | CHEMICAL MECHANICAL VAPOR DEPOSITION DEVICE FOR PRODUCTION OF BONE SUBSTITUTE MATERIAL - A method for fabricating a substitute component for bone, including the processes of: provision of a chemical spray including at least three of calcium chloride, hydrogen phosphate, hydrogen carbonate and water to form a combined solution; reaction and precipitation of the combined solution onto a substrate; allowing the precipitated particles to form a porous structure on the substrate; applying substantially isostatic pressure to the porous structure to form a compressed structure; and (optional) providing one or more through-holes in the compressed structure to promote osteoinduction. | 10-25-2012 |
20120321779 | CHEMICAL VAPOR INFILTRATION APPARATUS AND PROCESS - The present invention relates to improvements in chemical vapor infiltration processes and devices for depositing a biocompatible material onto a porous substrate to form an orthopedic implant. The substrate may be formed of reticulated vitreous foam and coated with tantalum, niobium, tungsten, or other biocompatible materials. | 12-20-2012 |
20130004651 | SUSTAINED DRUG RELEASE FROM BODY IMPLANTS USING NANOPARTICLE-EMBEDDED POLYMERIC COATING MATERIALS - The present invention relates to the preparation of therapeutic compositions including drug-containing nanoparticles for coating a body implant to provide for drug delivery in a locally applied and extended release manner and their methods of use to treat physiological conditions. | 01-03-2013 |
20130115364 | RESIN-INFILTRATED CERAMICS - Porous ceramic materials, including dental prostheses, may be infiltrated by a solution comprising resin monomers and a solvent for lowering viscosity of the solution. Infiltration may be achieved by providing the ceramic and the solution in a low pressure environment, followed by a polymerizing process whereby the resin is cross-linked within the pores of the ceramic. The solvent may be removed, for example, to leave substantially only the polymerized resin within the ceramic. | 05-09-2013 |
20130302512 | METHODS FOR ALTERING THE SURFACE CHEMISTRY OF BIOMEDICAL IMPLANTS AND RELATED APPARATUS - Methods for improving the antibacterial characteristics of a biomedical implant. In some implementations, the method may comprise providing a biomedical implant material block. The biomedical implant material block may comprise a silicon nitride ceramic material. The surface chemistry of the biomedical implant material block may be altered to improve the antibacterial characteristics of the biomedical implant material block. In some implementations, the surface chemistry may be altered by firing the biomedical implant material block in a nitrogen-rich environment or otherwise increasing the nitrogen content in the transitional oxide layer of at least a portion of the biomedical implant material block. The surface of the biomedical implant material block may also, or alternatively, be roughened to improve antibacterial characteristics of the implant. | 11-14-2013 |
20130302513 | DENTAL PROSTHETICS COMPRISING CURABLE ACRYLATE POLYMER COMPOSITIONS AND METHODS OF THEIR USE - Disclosed herein are acrylic and methacrylic acid ester-based polymeric materials containing as flexibilizing and brittleness reducing agents 1-60% of C | 11-14-2013 |
20140161965 | OPTICAL COMPOSITION FOR IMPRESSIONS OR REPLICAS OF SMALL OBJECTS - A method for preparing a 3-D impression or replica of small objects. It is particularly aimed at the dental field and provides improved optical texture of an impression or replica of a small object to enable imaging by photogrammetry. A composition useful in the method comprises a liquid curable polymer; macroparticles having a size greater than about 1 μm in diameter and microparticles present in a size range of less than about 1 μm such that the macroparticles and microparticles are present in a ratio in the range of between 5:1 and 15:1 (by volume); wherein the impression or replica formed from the composition has a surface particle distribution effective to allow imaging by photogrammetry. | 06-12-2014 |
20140328999 | Dynamic and Switchable Slippery Surfaces - The present disclosure describes a strategy to create self-healing, slippery liquid-infused porous surfaces (SLIPS) that can be modified as desired. Roughened (e.g., porous) surfaces can be utilized to lock in place a lubricating fluid, referred to herein as Liquid B to repel a wide range of objects, referred to herein as Object A (Solid A or Liquid A). Use of an external stimuli or degradation of the Liquid B can be utilized to change the characteristics of SLIPS structures reversibly or irreversibly that may be desired in a number of different applications. Numerous characteristics, such as adhesion, optical, mechanical, and the like, can be dynamically changed. | 11-06-2014 |
20150064339 | METHOD FOR MANUFACTURING AN IMPLANT MATERIAL - A method for manufacturing an implant material includes preparing a base material for implant, removing moisture from a chamber in which the base material is placed, and introducing material gas as a carbon source and a silicon source into the chamber after the removal of the moisture to form a carbon thin film containing a C—C component in which carbon atoms are bonded, and a SiC component in which carbon and silicon atoms are bonded on a surface of the base material by ionized deposition. | 03-05-2015 |
20150072067 | METHOD OF MANUFACTURE OF A PIECE DESIGNED TO BE FITTED IN THE AREA OF A DENTAL PROSTHESIS IN THE MOUTH OF A PATIENT - Method of manufacture of a piece designed to be fitted in the area of a dental prosthesis in the mouth of a patient, which comprises creating sugosities on the outer surface of the piece and applying a layer of TiN on the piece. The pieces allow the aesthetic results of the prosthetic treatment to be enhanced. It has also been shown that the manufactured pieces inhibit bacterial adhesion and are biocompatible. | 03-12-2015 |
20150086704 | Coating Spray System - Embodiments of the present invention include a spray bonder that comprises a bonder, a carrier, and, optionally, a propellant. Embodiments also include a coating spray system that comprises the spray bonder and a coating spray that includes a coating material, a carrier, and, optionally, a propellant. The coating material can be an opaque material, glass fit, opacious dentin, or the like. Also provided are methods for using the spray bonder and/or coating spray to coating objects, such as coating dental implants to match the color of a patient's gums. | 03-26-2015 |
20150132470 | FILM-PRODUCING DEVICE AND METHOD FOR PRODUCING ARTIFICIAL JOINT COMPONENT - It is an object, with regard to a configuration for forming a macromolecular layer on a surface of a base material of an artificial joint component, to achieve a size reduction, to accurately control ultraviolet irradiation intensity, to form a macromolecular layer having a uniform thickness, to suppress the influence of ultraviolet light on equipment and workers, and to make the occurrence of a malfunction unlikely. A film-producing device body forms a macromolecular layer in an inner surface of a base material of an artificial joint component, by means of photograft polymerization. The film-producing device body includes a plurality of ultraviolet LED elements and a work holder. On the work holder, solution containing macromolecular monomers is in contact with the inner surface of the base material. The ultraviolet LED elements emit ultraviolet light to a wider area than an area that each of the ultraviolet LED elements individually irradiates. | 05-14-2015 |
20180021136 | RAPID MANUFACTURING OF POROUS METAL PROSTHESES | 01-25-2018 |
427200270 | Inorganic oxygen-containing compound containing layer formed (e.g., hydroxyapatite, ceramic, glass) | 15 |
20080220148 | Methods for Production and Use of Synthetic Hydroxyapatite and Fluorapatite Nanorods, and Superstructures Assembled from the Same - Disclosed herein are methods directed toward the synthesis of ordered structures of hydroxyapatite and hydroxyapatite derivatives. More specifically, disclosed herein is a method of preparing ordered hydroxyapatite nanorod structures including the steps of suspending calcium and phosphate in a solvent, adjusting the pH to above 5, and heating to a temperature sufficient to support formation of the ordered hydroxyapatite nanorod structures. In some cases, the methods may include ethylenediamine tetraacetic acid or ethylenediamine tetraacetic acid derivatives. Also disclosed are methods that additionally involve a step of coating hydroxyapatite nanorods with a protein or an amphiphile such as a surfactant or polymer. | 09-11-2008 |
20080241353 | Biomimetic Process For Coating Substrates With A Biomimetic Solution Containing A Bioactive Substance And Use Of Said Process And Substrates In Bone, Connective Tissue-, Fat Tissue-And Muscle Tissue Engineering - The invention relates to a biomimetic process for coating a substrate, particularly a medical device, with a biomimetic composition, which comprises:
| 10-02-2008 |
20080254201 | Method for Preparing Endosseous Implants with Zircon Dioxide Coating - The method includes the following steps: formulation of liquid, non-gelled and stable precursors by solvolysis of ZV (IV) compounds; precursor deposition on endosseous implant surface; thermal treatment to achieve film densification, in the presence of oxygen, of a complex formed by the said endosseous implant and precursor, to obtain on the implant surface a thin nanocrystalline zirconium dioxide film. | 10-16-2008 |
20090148592 | Methods of Making Ceramic and Metal Compositions - A novel metal/ceramic hybrid material in which the void space of the ceramic is filled with metal. The metal may be bonded to the ceramic, for example by formation of a metal oxide. The metal may be introduced into the ceramic as small particles in a suspension then heated to melt the metal, allowing bonding to the ceramic or better filling of the void space. The hybrid material may be used in a variety of applications. | 06-11-2009 |
20090181161 | PROCESS FOR THE PREPARATION OF PROTEIN MEDIATED CALCIUM HYDROXYAPATITE (HAP) COATING ON METAL SUBSTRATE - This invention provides a process for the preparation of protein mediated calcium hydroxyapatite (HAp) coating on metal substrates particularly on stainless steel (316 L) by biomimetic route, capable of rapid and effective osteointegration with the host tissue following controlled interfacial reactions. For the purpose, calcium deficient, carbonated hydroxyapatite (HAp) coating was developed on metal substrates particularly on stainless steel (316L) alloy through biomimetic route after a surface treatment step using aqueous solution (4-10 wt %) of BSA at room temperature. The coating was characterised with respect to phase composition, crystallinity, morphology and thickness. The protein mediated calcium phosphate ceramic coating is porous (pore dia—100-200 μm) having uniform pore distribution and coverage. There is multifold enhancement in thickness and crystallinity (data provided) of the as-prepared coating. The process in the present invention is designed to mimic the structural and characteristic properties of the biological apatite to expedite osteointegration kinetics and to further improve biocompatibility of the metallic implant. | 07-16-2009 |
20100040767 | Process and Apparatus for Producing Three-Dimensional Shaped Ceramic Bodies - A process for producing three-dimensional shaped ceramic bodies by layerwise printing of a suspension comprising the constituents required for formation of the shaped ceramic bodies by means of an inkjet printer in the desired two-dimensional shape onto a support material, drying and hardening of the layer composite formed, which is characterized in that printing is effected using a suspension comprising from 50 to 80% by weight of ceramic particles in a dispersion medium comprising an aqueous boehmite sol, at least one low molecular weight alcohol, at least one drying inhibitor and at least one organic fluidizer, and also an apparatus for carrying out this process are described. | 02-18-2010 |
20100136214 | Acetabular Shell System and Method for Making - A method for forming an acetabular shell includes providing a working surface such as a mandrel, and spraying the working surface with a first layer of material having a first composition such as aluminum oxide. After a suitable thickness is generated, the spray composition is gradually changed to other compositions having desired particle sizes and distribution. In one example, the composition is changed to a mixture of aluminum oxide and titanium oxide and/or titanium. As thickness builds up, the relative amount of aluminum oxide is decreased such that the composition is all titanium and titanium oxide. After a desired thickness is generated, the acetabular shell is extracted off the mandrel. | 06-03-2010 |
20100247739 | Titanium oxide-organic polymer conjunction suitable for artificial bone - The titanium oxide-organic polymer composite material for artificial bone obtained by forming titania gel on the surface of said base material by titania solution treatment to dip into a solution of 0° C. to 50° C. temperature for from several seconds to 1 week obtained by adding a solution consisting of acidic alcohol and water into alcohol solution of titaniumtetraalcoxide to a base material composed of a polymer compound selected from a group consisting of polyolefin, polyester and nylon, and modifying to a titanium oxide membrane which forms apatite having similar Ca/P atom ratio to an apatite of mammalian's bone in supersaturated aqueous solution to apatite or from a body fluid of mammalian by dipping said base material on the surface of which titania gel is formed into hot water of. 50° C. to 95° C. or solution of room temperature to 95° C. to which acid is added. | 09-30-2010 |
20100323094 | POROUS BIOMATERIALS SURFACE ACTIVATION METHOD - The present invention relates to a porous biomaterials surface activation method by coating with a layer of apatitic nanocrystals in order to increase their surface reactivity. The method according to the invention is characterized by the following steps:
| 12-23-2010 |
20100330260 | Implant Depots to Deliver Growth Factors to Treat Osteoporotic Bone - The present invention relates to the design and composition of a depot implant for optimal delivery of growth factors to treat osteoporotic bone, in that such depot implant is constructed to be in a cylinder (rod) or sphere shape and have a natural or synthetic polymer scaffold with or without impregnated calcium phosphate particles. The density of the depot is higher than a typical BMP sponge carrier to facilitate it's implantation and slower release of the growth factor. The scaffold is such that it has adequate porosity and pore size to facilitate growth factor seeding and diffusion throughout the whole of the bone structure resulting in increased bone mineral density in the osteoporotic bone. In addition, the shape of the depot implant allows for delivery through a cannula or large bore needle. | 12-30-2010 |
20120058250 | METHOD FOR PREPARATION OF BIOACTIVE GLASS COATINGS BY LIQUID PRECURSOR THERMAL SPRAY - The present invention belongs to the field of biomedical material, and is particularly related to a method of preparing bioactive glass coatings by liquid precursor thermal spray. The objective of the present invention is to overcome the shortcomings of the air plasma spraying where the powder feedstock preparation is complicated and time-consuming, and sol-gel or other wet chemistry method where the synthesized coating generally has thin coating thickness and with low production efficiency. Therefore, a new method is provided for preparation of bioactive glass coatings. In this method, organic and inorganic raw materials were first weighed in accordance with the chemical composition of bioactive glasses, and sol or suspension was prepared; then the sol or suspension was used as the feedstock for thermal spray, and was deposited on the biomedical materials substrate, at high temperature to form the bioactive glass coating. The invention possesses the following advantages: simple operation, less complicated procedures, synthesis with high efficiency, low production cost, suitable for industrial production, and so on. This method can be used to prepare bioactive glass coatings. | 03-08-2012 |
20120135133 | METHOD FOR COATING METAL IMPLANTS WITH THERAPEUTIC MIXTURES - Disclosed herein are methods of treating an article surface. The method comprises delivering a polymer and drug to a medical implant having a porous surface and using at least one particle stream from at least one fluid jet to subsequently remove the polymer from the outer surface of the metal substrate, thereby retaining the therapeutic agent and polymer within the pores of the implant. | 05-31-2012 |
20130230640 | CERAMIC LAYERED MEDICAL IMPLANT - A new composition and medical implant made there from comprises a thick diffusion hardened zone, and layered ceramic surface. Orthopedic implants comprising the new composition, methods of making the new composition, and methods of making orthopedic implants comprising the new composition are disclosed. | 09-05-2013 |
20140127392 | DEPOSITION OF DISCRETE NANOPARTICLES ON A NANOSTRUCTURED SURFACE OF AN IMPLANT - A method of forming an implant to be implanted into living bone is disclosed. The method comprises the act of roughening at least a portion of the implant surface to produce a microscale roughened surface. The method further comprises forming a nanoscale roughened surface on the microscale roughened surface. The method further comprises the act of depositing discrete nanoparticles on the nanoscale roughened surface though a one-step process of exposing the roughened surface to a solution including the nanoparticles. The nanoparticles comprise a material having a property that promotes osseointegration. | 05-08-2014 |
20140377449 | METHOD FOR THE SURFACE TREATMENT OF TITANIUM BONE IMPLANTS USING, IN ORDER, A SODIUM HYDROXIDE BATH AND ANODIZATION - The invention relates to a method for the surface treatment of a biologically inert titanium implant to be placed in contact with a bone of the human body, which involves allowing body fluids, such as the inorganic portion of human blood plasma, to naturally deposit, onto the titanium implant, a calcium phosphate film having the formula Ca | 12-25-2014 |