| Entries |
| Document | Title | Date |
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| 20080206352 | Extract for Preventing or Treating Thrombotic Diseases - An extract for preventing or treating thrombotic disease, particularly, an extract of leech and/or earthworm with molecular weight of not more than 5800 Dalton, and processes for preparation, pharmaceutical compositions and uses thereof. The extract of the present invention has improved significantly safety without any reducing in pharmaceutical activities or the therapeutical effects as compared to existing products. | 08-28-2008 |
| 20080241269 | Methods of Applying Antimicrobial Formulations on Food - Methods for applying antimicrobials or other active agents onto food products, and particularly meat products, are described. The methods apply a controlled amount of treatment composition to the food product in an efficient fashion so that an excess of the solution is not required. | 10-02-2008 |
| 20090011041 | Compositions for Correcting Age Related Changes of a Human Endocrine System and Methods for Producing a Pharmaceutical Form Bases on Said Compositions - The present invention relates to anti-aging pharmacology and is intended for correction of age-related changes in human endocrine system. The essence of the invention is the compositions for correction of certain age-related endocrine changes and method for production of pharmaceutical form based thereon. Each composition contains a mixture of substances exhibiting hormonal activity (HA) or hormone-like activity (HLA) selected from the group: C21 or C19 steroids, pregnenolone, 17-hydroxypregnenolone, DHEA, progesterone, testosterone, or a hormone-like substance of herbal origin (HS), and also a dry methanolic of Nettle root extract, taken in a definite ratio, wherein HA, HLA or HS with the Nettle root extract can further contain a Deer Antler velvet extract and/or Ginseng root extract, and HS can comprise diosgenin or protodioscin. One variant of the composition is a mixture of a dry Ginseng root extract and a dry Nettle root extract. The inventive method for production of said pharmaceutical form consists in mixing an active component and pharmaceutically acceptable carrier with suitable adjuvants in an effective amount. The useful result is in broadening the range of natural agents able to correct age-related hormonal changes in human organism. | 01-08-2009 |
| 20090061012 | Shark Repelling Method and Repellent Incorporating Wax - A method of repelling sharks for limiting their attacking a surfboard user comprises applying a conventional surfboard traction improving solid wax that also incorporates a shark repellent such as a surfactant, a capsaicinoid or a semiochemical in a concentration based on the “Johnson & Baldridge Test”. The extent of application is consequently sufficient to render the coated surfboard foul tasting when bitten by a shark but insufficient to reliably repel a shark in response to the dispersion in the water of the repellent. The invention extends to a shark repellent incorporating surfboard coating wax. | 03-05-2009 |
| 20090061013 | METHODS OF ENHANCING THE QUALITY, NUTRITIVE AND HEALTH VALUES OF MEAT FROM BOVINE - The present invention relates to methods of increasing the selenium content in beef by feeding special enriched diets, methods of improving human immune function, such as providing anticancer benefits. The present invention further provides methods for improving the quality of beef meat through a special enhanced diet, wherein organic selenium, copper, zinc and manganese replace all inorganic and metallic forms. | 03-05-2009 |
| 20090068281 | Composition, Functional Food and Pharmaceutical Composition for Improvement in Obesity - A composition for improving obesity is disclosed. The composition contains a natural ingredient free of side effects in daily intake as an active ingredient. The composition is capable of remarkably reducing body fat, as compared with a conventional ingredient which is derived from a natural ingredient as an active ingredient, and is capable of suppressing fat storage. The composition includes a meat extract or a fish meat extract, and a fat storage suppressive substance. | 03-12-2009 |
| 20090087495 | Food for Improving Motor Function - A food for improving motor function comprising as effective components carnosine and/or anserine and a material for improving motor performance (a material for motor energy source, a material for promoting conversion into energy and/or an antioxidant) is provided. In the invention, by synergistic effect of these components, the motor function or stamina can be improved and recovery from fatigue can be promoted in humans and mammals. Further, any of the effective components of the food for improving motor function of the invention is a naturally occurring component, therefore, the food has a characteristic of high safety. | 04-02-2009 |
| 20090104278 | FOOD COMPOSITION FOR RECOVERY FROM FATIGUE - In the present application are disclosed a food composition for recovery from fatigue, comprising, as an effective ingredient, an extract of migratory fish such as a | 04-23-2009 |
| 20090148536 | Traditional chinese medicine composition to treat rheumatoid arthritis and Preparation method thereof - The present invention discloses a traditional Chinese medicine composition to treat Rheumatoid Arthritis and its preparation method. The composition is mainly comprised of the following crude drugs: ant, Radix Salviae Miltiorrhizae, Radix Aconiti Preparata, Radix Ginseng, Caulis Spatholobi, and Ramulus Cinnamomi, etc. According to pharmaceutical methods, various clinical acceptable dosage forms can be prepared of the composition of the present invention, including but not limited to one of the following dosage forms: tablets, capsules, pills, granules, suspension, dripping pills, oral liquid preparation, etc. The drug of the present invention has the functions of invigorating the kidney and spleen, promoting blood flow and clearing out the vein, expelling wind-evil and removing wetness, eliminating cold to stop pain. It can be effectively used in the treatment of lingering arthralgia with weak, arthralgia, intumesce and morning stiffness, numbness and stickiness, difficult to flex and extend, rigor and deforming, the rheumatism and rheumatoid arthritis with the above symptoms. | 06-11-2009 |
| 20090162452 | EB Matrix Production From Animal Tissue And Its Use For Tissue Repair - A method of forming and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue to chemical and mechanical processing. In addition to skin tissue, another source of EBM is a blood vessel. EBM may be used for hernia repair, colon, rectal, vaginal and or urethral prolapse treatment; pelvic floor reconstruction; muscle flap reinforcement; lung tissue support; rotator cuff repair or replacement; periosteum replacement; dura repair; pericardial membrane repair; soft tissue augmentation; intervertebral disk repair; and periodontal repair. EBM may also be used as a urethral sling, laminectomy barrier or spinal fusion device. | 06-25-2009 |
| 20090202653 | Compositions and method for enhancing proteoglycan production - The present invention provides compositions comprising notochord enriched media and/or one or more factors derived therefrom. Such compositions are useful for enhancing the production of proteoglycan in cells or animals in need thereof, for example for treating degenerative disc disease. The notochord enriched media is preferably obtained from a nonchondrodystrophic animal. | 08-13-2009 |
| 20090238891 | Method of producing a dry earthworm powder - Provided is a method of producing a dry earthworm powder without deterioration in useful pharmacological action, by removing dirt on the skin of earthworms while allowing the earthworms to excrete the digest remaining in the digestive tracts efficiently without weakening the earthworms, which comprises the steps of: standing living earthworms under light for 10 to 50 hours, removing the dirt formed on the skin thereof, adding an organic acid to the living earthworms, diluting the acid rapidly with addition of water, adjusting the pH of the aqueous acidic solution to 2 to 5, standing the earthworm mixture for 3 to 180 minutes under the pH condition, washing the earthworms with water, grinding the earthworms into a homogenate, freezing the homogenate at −18° C to −35°0 C, keeping the frozen homogenate for 20 to 240 hours, and freeze-drying and degassing the frozen homogenate under vacuum simultaneously. | 09-24-2009 |
| 20090238892 | DEER ANTLER EXTRACT FOR PROMOTING ANGIOGENESIS - An isolated extract of deer velvet which contains components which have molecular weights that are substantially are less than or equal to 10 kDa and which have a proliferative effect on endothelial cells and/or promote angiogenesis. | 09-24-2009 |
| 20090269415 | NOVEL THERAPEUTIC AGENT DERIVED FROM MARINE ORGANISM - There is provided a nerve repairing agent, anti-ulcer agent or the like comprising an extract from a marine organism selected from organisms belonging to the class Holothuroidea, the phylum Porifera and the order Actiniaria or a material removed from a viscus of the organism. The extract has the following properties (1) to (4): (1) it is a almost colorless, transparent and viscous liquid having a slight fishy smell, or a almost white powder having a slight fishy smell which, when dissolved in water, is almost colorless and viscous; (2) a solution prepared by dissolving the liquid or powder in water shows the maximum absorbance at a wavelength of 264±10 nm; (3) a solution prepared by dissolving the liquid or powder in water shows an acidic pH value; and (4) it has at least one effect selected from a cranial nerve repairing effect, a nerve-growing effect, an insulin-releasing effect, an immunopotentiating effect, a noxious pain preventive effect, a neurogenic pain preventive effect, a diabetic sensory neuropathy ameliorating effect and an ulcer preventive effect. | 10-29-2009 |
| 20090317482 | METHODS AND COMPOSITIONS FOR TREATING CONGESTIVE HEART FAILURE - Compositions and methods for treating congestive heart failure are provided herein. | 12-24-2009 |
| 20100015241 | AVIAN-BASED INSECT REPELLENT - The invention provides an insect repellent that repels flies, gnats, mosquitoes, lice, ticks, and fleas. The insect repellent comprises an avian-based extract, in particular an extract isolated from birds of the order Psittaciformes (parrots). The invention also provides an insect repellent composition about 5 volume% to about 75 volume % of the avian-based extract and about 95 volume % to about 25 volume % of a carrier vehicle. | 01-21-2010 |
| 20100015242 | USE OF A COMPOSITION FOR SKIN TREATMENT UNDER X-IRRADIATION - The invention relates to the use of a composition in the production of a dermatological agent for skin treatment under repeated X-irradiation. The composition includes oxygen-bearing asymmetrical lamellar aggregates of phospholipids and fluorocarbons as well as specific water-soluble antioxidants, said composition having a radical protection factor of at least 4000×10 | 01-21-2010 |
| 20100034897 | Method for Removal or Inactivation of Heparin - The present invention relates to the use of immobilized RAGE or portions thereof for removal of heparin and low molecular weight heparin from a fluid sample or from a patient in need of neutralization of anticoagulant activity. The invention provides a method for removal or inactivation of heparin and low molecular weight heparin, as well as a device which utilizes this method. | 02-11-2010 |
| 20100047360 | Use Of Polyamines In The Treatment Of Psoriasis - The present invention provides unbranched aliphatic polyamines for use in therapy, particularly for use in the treatment of psoriasis and compositions containing polyamines. | 02-25-2010 |
| 20100074962 | DEGRADATION OF PRION PROTEIN AND REDUCED PRION INFECTIVITY BY EARTHWORM HOMOGENATES - Methods for the degradation of prion proteins are described. Items that may be contaminated with prions are treated with earthworm-derived extracts to degrade prion proteins and reduce their infectivity in animals. Methods of using an earthworm-derived protein extract for treating foodstuffs and surfaces to inhibit or disable prion infectivity are disclosed. Also disclosed are methods for treating medical instruments, tools used to butcher animals, and laboratory equipment. | 03-25-2010 |
| 20100080853 | Use of Spongilla Spicules as a Dermabrasion Device or Resurfacing Modality - Dermabrasive compositions for skin resurfacing are disclosed. Therapeutic compositions disclosed are derived from Porifera species, specifically sponges, and more specifically fresh water sponges. One disclosed embodiment is derived from | 04-01-2010 |
| 20100119613 | PROCESS TO ACTIVATE EXTRACTS DERIVED FROM LIVING ORGANISMS USING LONG WAVE UV IRRADIATION AND COMPOSITIONS COMPRISING SAID ACTIVATED EXTRACT - The present invention relates to a method for producing an extract which is capable of inducing an antioxidant stress response comprising the step of treating an extract from organic material with UV light, said extract being derived from a non-mammalian cell or a non-mammalian organism and said cell or organism being capable of synthesizing polyunsaturated fatty acids. Furthermore, an extract capable of inducing an antioxidant stress response produced in accordance with the inventive methods, in particular an extract capable of inducing an antioxidant stress response for the preparation of a cosmetic composition is disclosed. The present invention also relates to a cosmetic composition comprising the inventive extract obtainable by the method provided herein. | 05-13-2010 |
| 20100124573 | EXTRACELLULAR MATRIX COMPOSITIONS FOR THE TREATMENT OF CANCER - The present invention is directed to methods of inhibiting cancer cell growth or proliferation by contacting the cancer cell with an extracellular matrix (ECM) composition. Also provided are methods of delivering a chemotherapeutic agent to a cancer cell by contacting a cancer cell with an extracellular matrix composition containing a chemotherapeutic agent. Also provided are compositions containing ECM and a chemotherapeutic agent. | 05-20-2010 |
| 20100183733 | HAIR GROWTH-INHIBITING AGENT - A hair removing agent or a hair growth inhibiting agent is provided by determining an endogenous factor having a hair growth inhibitory activity, screening for substances having an activity similar to that of the endogenous factor or substances enhancing the activity or expression of the endogenous factor, and utilizing the physiological activities of such substances. It has been found that FGF18 inhibits hair growth. A method of screening for FGF18-like active substances, substances that promote the activity of FGF18 or substances that promote the expression of FGF18 to thereby obtain candidates for the hair growth inhibiting agent or hair removing agent is disclosed. Also disclosed is a hair growth inhibiting agent or a hair removing agent comprising, as an active ingredient, FGF18 and/or an FGF18 partial peptide, or an FGF18-like active substance and/or a substance that promotes the activity or expression of FGF18 (e.g., Digenea simplex extract). | 07-22-2010 |
| 20100203154 | Elasmobranch-Repelling Compounds, Methods of Use and Devices - Elasmobranch-repelling compositions are prepared from elasmobranch carcasses. Extraction of these elasmobranch carcasses with polar solvent after a period of aerobic decay yields semiochemical repellents that induce a flight reaction in sharks when introduced into the sharks' oceanic proximity. | 08-12-2010 |
| 20100221358 | Synthetic derivatives beta glycolipids and compositions thereof for the treatment of pathologic disorders - The invention relates to novel synthetic derivatives of β-glycolipids and uses thereof as immunomodulators. More particularly, the invention relates to synthetic derivatives of β-glycolipids, specifically, the compounds of any one of Formula I, II III and IV or any mixture or combination thereof, and particularly the ALIB-97 (Formula II) derivative and uses thereof for the treatment of different pathologic disorders, particularly, immune-related hepatic disorders and pathologies associated with the metabolic syndrome. | 09-02-2010 |
| 20100255113 | HERBAL COMPOSITION FOR TREATMENT OF NEURODEGENERATION AND NEURONAL DYSFUNCTION - This invention provides methods of using various herbal compositions to treat neurodegenerative diseases and neuronal dysfunctions, said compositions comprise a combination of Radix | 10-07-2010 |
| 20100260861 | TREATMENTS WITH HELMINTHS - The invention relates to a method of treating obesity or IBS in an individual by administering a physiologically acceptable composition comprising a helminthic parasite, or an active variant thereof, that is of a type and present in an amount sufficient to treat the individual for obesity or IBS. The invention is not limited to obesity and IBS and is further drawn to conditions of health in which the microbiota profile for a population of microbes found within an individual contributes to a pathological condition. | 10-14-2010 |
| 20100285145 | GPR 119 MODULATORS - Compounds of Formula (I) that modulate the activity of the G-protein-coupled receptor GPR119 and their uses in the treatment of diseases linked to the modulation of the G-protein-coupled receptor GPR119 in animals are described herein. | 11-11-2010 |
| 20100323027 | MESENCHYMAL STEM CELL CONDITIONED MEDIUM - We disclose a method of preparing a conditioned cell culture medium, the method comprising the steps of: (a) culturing a mesenchymal stem cell (MSC), a descendent thereof or a cell line derived therefrom in a cell culture medium; and (b) optionally isolating the cell culture medium; in which the mesenchymal stem cell (MSC) is obtained by propagating a cell obtained by dispersing a embryonic stem (ES) cell colony, or a descendent thereof, in the absence of co-culture in a serum free medium comprising FGF2. | 12-23-2010 |
| 20110003008 | MESENCHYMAL STEM CELL PARTICLES - We describe a particle secreted by a mesenchymal stem cell and comprising at least one biological property of a mesenchymal stem cell. The biological property may comprise a biological activity of a mesenchymal stem cell conditioned medium (MSC-CM) such as cardioprotection or reduction of infarct size. The particle may comprise a vesicle or an exosome. | 01-06-2011 |
| 20110020459 | Microfluidic method and system for isolating particles from biological fluid - The invention relates to a system and method for isolating particles from a biological fluid, including: obtaining a sample of biological fluid from a source (e.g. a patient) in which the sample contains particles of multiple sample particle types; tagging particles in the sample with tagging agents, including mixing the sample with a solution of magnetic tagging agents that selectively bind to particles of at least one of the sample particle types, thereby forming a group of tagged particles in the sample; passing the sample through a magnetic conduit having a magnetic field that interacts with at least some of the tagged particles; sorting the particles of the sample into multiple groups based on the interaction between the tagged particles and the magnetic field; and optionally returning selected portions of the processed fluid back to its source with or without the addition of appropriate therapeutic agents. | 01-27-2011 |
| 20110020460 | GPR 119 MODULATORS - Compounds of Formula I that modulate the activity of the G-protein-coupled receptor GPR119 and their uses in the treatment of diseases linked to the modulation of the G-protein-coupled receptor GPR119 in animals are described herein. | 01-27-2011 |
| 20110045098 | EXCITATORY GLYCINE RECEPTORS AND METHODS - The invention provides isolated N-methyl-D-aspartate type 3B (NR3B) polypeptides, functional fragments and peptides, encoding nucleic acid molecules and polynucleotides, and specific antibodies. Also provided are excitatory glycine receptors, containing either NR3B or NR3A polypeptides. Further provided are methods for detecting excitatory glycine receptor ligands, agonists and antagonists. The invention also provides related diagnostic and therapeutic methods. | 02-24-2011 |
| 20110064822 | BIOMATERIAL AND PREPARATION METHOD THEREOF - A biomaterial prepared from a process comprising dehydrating the fish scales until the fish scales containing less than about 50% of water, and grinding the dehydrated fish scales into ground particles each having an average size of less than about 10,000 μm in diameter, wherein the ground particles contain a mixture of sponge like matrix and powder is provided. The invention also provides a biomaterial prepared from fish scales by a process comprising subjecting the fish scales to a heat treatment at a temperature of less than about 200° C. | 03-17-2011 |
| 20110076338 | Composition for Skin Protection and Methods of Making Same - Skin care formulations having tamanu oil in amounts providing effective rates of protection for antimicrobial and anti-aging properties, including but not limited to promoting the formation of new tissue, scar healing and skin repair, anti-inflammatory, anti-bacterial, anti-fungal, anti-oxidant, and combinations thereof. | 03-31-2011 |
| 20110081423 | Tissue Stabilization for Heart Failure - Methods and devices for the stabilization of heart tissue to treat congestive heart failure using a therapeutic composition are discussed. The therapeutic composition can comprise an elastin stabilization agent, a collagen stabilization agent, or a combination thereof and be applied to the pericardium, to the outer surface of the myocardium, or a combination thereof using a catheter type of device with an attached reservoir. Controlled placement and release of the therapeutic composition can be achieved using a delivery vehicle to formulate the composition. | 04-07-2011 |
| 20110086105 | METHODS FOR IDENTIFYING NOVEL NUCLEIC ACID REGULATORY ELEMENTS AND COMPOUNDS THAT AFFECT THE REGULATION - Described herein are methods for identifying novel nucleic acid regulatory elements and compounds that modulate the regulation of such elements. Also described herein are nucleic acid sequence identified as novel nucleic acid regulatory elements and host cells containing such nucleic acid regulatory elements in a vector. | 04-14-2011 |
| 20110086106 | METHOD OF PRODUCING A DRY EARTHWORM POWDER - Provided is a simple and easy method of producing an innoxious dry earthworm powder, while suppressing inactivation of the enzymes contained in earthworms. In the method, a homogenate obtained by grinding living earthworms is freeze-dried and the dried product is heat-treated at a temperature of 110° C. or higher but lower than 130° C. Preferably, the method according to the present invention comprises further a process for preparation of the living earthworms, which precedes the grinding step, comprising the steps of: standing the living earthworms under light for 10 to 50 hours; removing the dirt formed on the skin thereof, bringing the earthworms into contact with an organic acid for 30 seconds or less; diluting the acid with addition of water to adjust the pH of the aqueous acidic solution to a pH in the range of 2 to 5; standing the earthworm mixture under the pH condition for 3 to 180 minutes; and then washing the earthworms with water. | 04-14-2011 |
| 20110091567 | TISSUE ORGANIZING STRUCTURE AND THERAPEUTIC METHODS - A novel cellular component, tissue organizing structure, and methods for use in detection, diagnosis and treatment of disease is described herein. Particularly, clinical applications include tissue generation from individual cellular components, gene transfer therapeutics and its use as a novel target for cancer prevention and therapeutics. More particularly, methods for disease and cancer prevention, detection, diagnosis and treatment are provided. | 04-21-2011 |
| 20110091568 | MEDIA CONDITIONED BY STEM CELLS AND USES THEREFOR - Compositions for application to the skin of individuals in need thereof are provided that include media conditioned by the growth of human stem cells, particularly human neural stem cells. In some embodiments, the stem cells are grown without the use of feeder layers. | 04-21-2011 |
| 20110091569 | ECHINODERM-DERIVED EXTRACTS, METHODS OF PREPARATION AND USES THEREOF - An Echinozoa tissue or organ extract comprising antioxidant compounds is disclosed. Also disclosed is a process for obtaining an Echinozoa tissue or organ extract, as well an extract obtained by this process. Compositions comprising such an extract are also described. Uses of such extracts/compositions, as well as corresponding methods of treatment, for example as an antioxidant or to decrease or inhibit oxidative stress in a cell, tissue or subject are also described. | 04-21-2011 |
| 20110111045 | Pharmaceutical composition for preventing and treating cell proliferative disease comprising mixture of feather of birds and scale of fish as an active ingredient - The present invention relates to a pharmaceutical composition for preventing and treating cell proliferative diseases comprising a feather of birds and a scale of fish, a scale transformed from the dermis, a degenerated or cornified variant of a scale, or a scale or horny scale of reptiles as an active ingredient. More particularly, the present invention relates to a pharmaceutical composition for preventing and treating cell proliferative diseases comprising a mixture of 70-85 weight % of a feather of birds and 15-30 weight % of a scale of fish, a scale transformed from the dermis, a degenerated or cornified variant of a scale, or a scale or horny scale of reptiles as an active ingredient. The inventive composition has the effect of inhibiting and preventing growth of cancer cells. Accordingly, the inventive composition may be used for anticancer purposes to prevent, ameliorate or treat cancer. | 05-12-2011 |
| 20110111046 | N1-Pyrazolospiroketone Acetyl-CoA Carboxylase Inhibitors - The invention provides a compound of Formula (I) | 05-12-2011 |
| 20110123638 | METHOD FOR THE INTRADERMAL DELIVERY OF SUBSTANCES - This invention describes method to facilitate intradermal delivery of a great variety of active substances, especially including high molecular weight cosmicuticals. Also disclosed is a method of applying the composition of matter resulting from the method topically to patients, especially using a cream or patch. The active substance is initially combined with a biopolymer, which combination is subsequently linked to a base formulation whereby the base formulation aids in the intra-dermal delivery of the active substance without the skin irritation limitations of other formulations and dermal transmitting methods. The method of using a combination of natural herbal, vegetable and animal products combined in this invention with biopolymers permits molecules of higher molecule weight to penetrate into the skin in a bioactive form by passive delivery means. The invention includes a method for the improvement of skin health and wrinkle reduction. | 05-26-2011 |
| 20110142953 | COMBINATIONS OF IMMUNOSUPPRESSIVE AGENTS FOR THE TREATMENT OR PREVENTION OF GRAFT REJECTIONS - A pharmaceutical composition useful in the treatment or prevention of transgenic xenograft rejection comprising immunosuppressant compounds selected from the group consisting of an IL-2 transcription inhibitor and immunosuppressant compounds that immunosuppress for B-cell-mediated or antibody-mediated rejection of xenografts, and pharmaceutically acceptable diluents or carriers, and a method of preventing hyperacute rejection, reducing early graft damage, improving early xenograft function and promoting long term survival of said transgenic xenografts comprising the steps of i) contacting the body fluid removed from a human recipient with a xenoantigenic material which is bound to a biocompatible solid support, ii) reintroducing the treated body fluid into the recipient, and iii) treating the recipient with said pharmaceutical composition. | 06-16-2011 |
| 20110217385 | Method for extracting mesenchymal stem cell from human or animal embryo and for extracting the secretion product thereof - The present invention relates to a method of extracting mesenchymal stem cells from human or animal embryo, comprising: A. taking the sample based on human or animal embryo, centrifuging the sample; B. digesting the sample with enzyme digestion solution, and making single cell suspension, wherein said enzyme digestion solution comprises trysin-EDTA and collagenase IV; C. adding mesenchymal stem cell culture medium A to the isolated single cells, inoculating and culturing the cells; D. treating the cells with adherence purification, and obtaining mesenchymal stem cells by magnetic sorting. The present invention also relates to a method of extracting the secretion product from mesenchymal stem cells, the use of the secretion product in the aspects of cosmetic and healthcare, and an epidermal cell repairing lotion made using the secretion product. In the process according to the present invention of extracting mesenchymal stem cells from human or animal embryo, the mixture of trypsin-EDTA and collagenase IV is used as the enzyme digestion solution, enabling to obtain the maximal number of single cells, while reducing cell damage to the lowest level. | 09-08-2011 |
| 20110236499 | DERMAL COMPOSITIONS CONTAINING GORGONIAN EXTRACT - A skincare composition comprising Gorgonian extract as an anti-inflammatory component thereof, said skincare composition being selected from among compositions (I) and (II): (I) an aqueous composition comprising from 35 to 65 wt.% water, from 25 to 45 wt.% surfactant, from 0.01 to 0.2 wt.% retinol and from 0.005 to 0.5 wt.% Gorgonian extract, wherein all weight percentages are based on total weight of the aqueous face wash composition, and all weight percentages of all ingredients in the aqueous face wash composition total to 100 wt. %; and (II) a gel composition comprising from 60 to 90 wt.% water, from 1 to 12 wt.% benzoyl peroxide, and from 0.05 to 1.25 wt.% Gorgonian extract, wherein all weight percentages are based on total weight of the gel composition, and all weight percentages of all ingredients in the gel composition total to 100 wt.%. | 09-29-2011 |
| 20110256232 | ANTIMICROBIAL COMPOSITION FROM COPEPODS - The present invention relates to an antimicrobial composition, and to a process for the preparation of such a composition. The invention also relates to the use of such an antimicrobial composition. The present invention further relates to the use of the antimicrobial composition as a pharmaceutical. | 10-20-2011 |
| 20110280950 | SYNERGISTIC ANTIOXIDANT COMPOSITIONS - Antioxidant compositions for the stabilization of fat sources against oxidation, stabilized fat source compositions, and methods of stabilizing fat sources against oxidation are described. In particular, an antioxidant emulsion that includes quercetin in addition to at least one other ingredient and a lipid carrier is described. | 11-17-2011 |
| 20110280951 | COMPOSITION FROM SPHAERANTHUS INDICUS AND GARCINIA MANGOSTANA FOR THE CONTROL OF METABOLIC SYNDROME - The invention relates pharmaceutical/dietary supplement/food ingredient(s) selected from the extract(s), fraction(s), active compound(s) and phytochemical(s) or mixtures thereof derived from | 11-17-2011 |
| 20120009269 | RANGE OF ASEPTICALLY PRODUCED INFANT FOODS HAVING LOW CONCENTRATIONS OF UNDESIRED BY-PRODUCTS AND METHODS FOR MAKING THE SAME - A range of infant food products wherein each product in the range includes minimal levels of undesired by-products produced during processing as indicated by less than about 15 micrograms furan per kg food product. | 01-12-2012 |
| 20120121719 | METHODS OF MAKING AND USING THREE-DIMENSIONAL EXTRACELLULAR MATRICES - Three-dimensional extracellular matrices lacking synthetic scaffolds are provided. Methods of making the three-dimensional extracellular matrices and methods of using the three-dimensional extracellular matrices are also provided. | 05-17-2012 |
| 20120171298 | USE OF PHARMACEUTICAL COMPOSITIONS IN PREPARING PHARMACEUTICALS FOR TREATING DIABETIC ULCER - The use of pharmaceutical compositions in preparing pharmaceuticals for treating diabetic ulcer in limb or on body surface, or in preparing medical dressing. The pharmaceutical compositions consist of (A) 3 to 15% by weight of edible beeswax and (B) 85 to 97% by weight of sesame oil extract of | 07-05-2012 |
| 20120183624 | METHOD FOR MANUFACTURING HOMEOPATHIC PERSONAL CARE PRODUCTS - A method for making a personal care composition including homeopathic remedies and essential oils. The homeopathic remedies are selected from one or more pharmacopeias wherein the remedies are indicated for one or more biological conditions. Remedies are selected because they are indicated for the same disease condition or in certain embodiments related conditions. Once selected the remedies are diluted to a predetermined concentration and blended with essential oils. In certain embodiments a medicated cleansing bar, a soap, or a cleansing material may be selected for delivering the homeopathic remedy and the essential oils. The essential oils may be extracted from plant material using various techniques including distillation. | 07-19-2012 |
| 20120219632 | METHODS FOR MONITORING CELLULAR STATES AND FOR IMMORTALIZING MESENCHYMAL STEM CELL - We describe a method of monitoring the state of a cell, the method comprising establishing, for a selected microRNA (miRNA) species secreted by the cell, a ratio of: (a) a precursor form of the miRNA species (pre-miRNA); to (b) a mature form of the miRNA species (mature miRNA); in which the pre- to mature miRNA ratio so established is indicative of the state of the cell. We also describe a method comprising the steps of: (a) providing a mesenchymal stem cell (MSC); and (b) introducing an oncogene into the mesenchymal stem cell to thereby transform it; in which the transformed mesenchymal stem cell does not secrete a gene product of the oncogene into a medium in which it is grown. | 08-30-2012 |
| 20120237607 | Immortalized cell compositions and compositions derived therefrom - The invention is directed to immortalized cell compositions and compositions derived therefrom. The invention is further directed to methods of making and using such immortalized cell compositions and compositions derived therefrom. Such immortalized cell compositions include but are not limited to Immortalized Amnion-derived Multipotent Progenitor cells (herein referred to as I-AMP cells) and conditioned media derived therefrom (herein referred to as I-Amnion-derived Cellular Cytokine Solution or I-ACCS). | 09-20-2012 |
| 20120282344 | FORMULATION FOR THE BIOLOGICAL CONTROL OF INSECT-PESTS - A formulation for the biological control of pests comprises a cohort of infective juvenile insect-parasitic nematodes from at least three species, wherein at least two of the species are of a first genus, and at least one of the species is from a second genus, and the species number from the first genus is greater than the species number from the second genus. The cohort of nematodes consists essentially of two species from the first genus and one species from the second genus and comprises at least one ambusher foraging species of nematode from a first genera and at least two cruiser foraging species of nematode from a different genera, or at least two ambusher foraging species of nematode from the same genera and at least one cruiser foraging species of nematode from a different genera. The first and second genus are selected from the group comprising: Steinernematidae and Heterorhapditidae. | 11-08-2012 |
| 20120294949 | METHODS OF PRODUCING STEM CELL CONDITIONED MEDIA TO TREAT MAMMALIAN INJURIES OR INSULTS - Methods of producing stem cell conditioned media to treat mammalian injuries or insults. In at least one embodiment of a method of producing a stem cell conditioned media of the present disclosure, the method comprises the steps of culturing at least one stem cell in a first cell culture medium, replacing some or all of the first cell culture medium with a second cell culture medium and further culturing the at least one stem cell in the second cell culture medium, and collecting a quantity of the second cell culture medium after a culture duration, wherein the quantity of the second cell culture medium contains a cell culture byproduct effective to treat a mammalian insult or injury. In another embodiment, the step of culturing comprises culturing the at least one stem cell in EGM2MV. | 11-22-2012 |
| 20120294950 | METHOD FOR PRODUCING DRY EARTHWORM POWDER - A method for producing dry earthworm powder, by which dry earthworm powder having high-titer enzymes can be produced while removing toxic substances contained in the bodies of earthworms, is provided. The method comprises:
| 11-22-2012 |
| 20120308664 | AVIAN-BASED INSECT REPELLENT - The invention provides an insect repellent that repels flies, gnats, mosquitoes, lice, ticks, and fleas. The insect repellent comprises an avian-based extract, in particular an extract isolated from birds of the order Psittaciformes (parrots). The invention also provides an insect repellent composition about 5 volume % to about 75 volume % of the avian-based extract and about 95 volume % to about 25 volume % of a carrier vehicle. | 12-06-2012 |
| 20130129831 | Compositions for Regenerating Defective or Absent Myocardium - Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function. | 05-23-2013 |
| 20130149386 | CD36 AS BIOMARKER FOR STEATOSIS - A method is provided for early treatment of steatosis, which method is based on early detection of steatosis based on the detection of CD36. CD36 is determined in a body fluid, and CD36 levels above a predetermined value is indicative of steatosis. | 06-13-2013 |
| 20130149387 | BIODEGRADABLE TISSUE COMPOSITION WITH BIODEGRADABLE CROSS-LINKERS - Novel implantable tissue fixation methods and compositions are disclosed. Methods and compositions of tissue, fixed using polymeric and/or variable length crosslinks, and di- or polymercapto compounds are described. Also described are the methods and compositions wherein the tissue is fixed using biodegradable crosslinkers. Methods and compositions for making radio-opaque tissue are also described. Methods and compositions to obtain a degradable implantable tissue-synthetic biodegradable polymer composite are also described. Compositions and methods of incorporating substantially water-insoluble bioactive compounds in the implantable tissue are also disclosed. The use of membrane-like implantable tissue to make an implantable drug delivery patch are also disclosed. Also described are the compositions and methods to obtain a coated implantable tissue. Medical applications implantable tissue such as heart valve bioprosthesis, vascular grafts, meniscus implant, drug delivery patch are also disclosed. | 06-13-2013 |
| 20130224305 | METHODS OF IDENTIFYING INSECT-TRPA1 MODULATORS - The invention provides a screening method for identifying an insect-specific TRPA1 modulator by comparing modulation of an insect TRPA1 and a mammalian TRPA1. The invention further provides method of insect control by applying to an insect a insect-specific TRPA1 modulator identified by the screening method. | 08-29-2013 |
| 20130259950 | METHOD FOR PREPARING SUPPLEMENT USING PETTITOES OR PIG'S HEAD AND ZANTHOXYLUM PIPERITUM, AND COMPOSITION THEREOF - The present invention relates to a dietary supplement capable of treating and preventing symptoms of immune diseases (reduced immunity, allergic disease, and respiratory disease), viral diseases (cold, varicella, and herpes zoster), musculoskeletal diseases (arthritis, traffic accident sequela, sciatica, frozen shoulder, and herniated disk), neurological diseases (insomnia, menopausal disorder, hypothermia, cold hands and feet, dysautonomia, and postpartum pain), and the like. More specifically, the dietary supplement is prepared by the following steps: preparing pettitoes or a pig's head in cold water for about 24 hours to remove blood and to wash the same; preparing | 10-03-2013 |
| 20130280340 | Compositions and methods of using lamellar bodies for modifying linear biological macromolecules - Compositions comprising therapeutically effective amounts of lamellar bodies to restore lubricity and non-stick properties to mucous surfaces for conditions characterised by dry adherent surfaces, particularly those surfaces close to the body openings and conditions of the eye. | 10-24-2013 |
| 20130309315 | PORIFERA-BASED THERAPEUTIC COMPOSITIONS FOR TREATING AND PREVENTING SKIN DISEASES - Methods and protocols of harvesting and processing of Porifera species, specifically sponges, and more specifically fresh water species of Genus | 11-21-2013 |
| 20140093581 | Avian-Based Treatment for Microbial Infections - A method for treating or preventing microbial skin infections comprising the step of: administering to a subject in need thereof a composition comprising avian extract EP-2 in a therapeutically effective concentration together with a pharmaceutically acceptable carrier and/or diluent. | 04-03-2014 |
| 20140105996 | Avian-Based Treatment - A method for treating or preventing proliferative skin disorders, cancers or pre-cancers comprising the step of: administering to a subject in need thereof a composition comprising avian extract EP-2 in a therapeutically effective concentration together with a pharmaceutically acceptable carrier and/or diluent. | 04-17-2014 |
| 20140154331 | TYROSINASE INHIBITOR PRODUCED USING DRIED EARTHWORM POWDER, AND METHOD FOR PRODUCING SAME - The present invention provides a highly safe tyrosinase inhibitor having excellent tyrosinase-inhibiting action, and a method for producing the tyrosinase inhibitor. The method for producing a tyrosinase inhibitor comprises the steps of contacting a live earthworm with hydroxycarboxylic acid powder, diluting the resulting mixture with water to adjust the pH to 2 to 5, and then leaving the resulting dilution to stand for 3 to 180 minutes, or contacting a live earthworm with an aqueous solution of hydroxycarboxylic acid having a pH of 2 to 5 and then leaving the resulting mixture to stand for 3 to 180 minutes; followed by washing the live earthworm with water, grinding the washed earthworm, and then freeze-drying the obtained ground product. | 06-05-2014 |
| 20140161897 | METHOD FOR TREATING CANCERS, SUCH AS MYELOMA AND BREAST CANCER, WITH A COMBINATION OF TBL-12 AND VELCADE - The invention relates to the use of TBL-12 in combination with at least one drug known to be effective against a specific cancer, but at a dose below its minimal effective dose when used alone. Among the types of cancer contemplated for treatment are multiple myeloma, breast, prostate, and cervical cancer. For multiple myeloma, combination with Velcade is envisioned. | 06-12-2014 |
| 20140161898 | Methods and Compositions for Treating Skin - A method for treating intact irritated or inflamed skin with a composition comprising at least one Histamine Receptor pathway inhibitor; at least one Lipoxygenase pathway inhibitor; at least one Cyclooxygenase pathway inhibitor and at least one Chemotaxis pathway inhibitor. | 06-12-2014 |
| 20140170230 | COMPOSITE OF NATURAL FOODS FOR ENHANCING NORMALIZATION OF TEAR SECRETION - The invention is in relation to a composite, which enhances normalization of tear secretion, and is made of selections from natural foods as eels, soybeans, oats, corn, champignons and sesames. Moreover, through above-mentioned natural foods, there are contents of vitamins, including vitamin B | 06-19-2014 |
| 20140193511 | Compositions Of Functional Mitochondria And Uses Thereof - Mitochondrial compositions and therapeutic methods of using same. Compositions of partially purified functional mitochondria and methods of using the compositions to treat conditions which benefit from increased mitochondrial function by administering the compositions to a subject in need thereof. | 07-10-2014 |
| 20140271904 | METHODS FOR PREPARING TISSUE IMPLANTS - A method is provided for preparing a biological tissue for implantation. The method includes providing a biological tissue from a human or animal donor, treating the biological tissue with an antiviral treatment formulation, lysing the biological tissue, decellularizing the biological tissue with a decellularization treatment formulation, and decontaminating the biological tissue with an alkaline alcohol solution. The antiviral treatment formulation may include a solution of peracetic acid and an alcohol, wherein the peracetic acid is present in the antiviral treatment formulation at a concentration from about 0.03% to about 1.2% (v/v). The decellularization solution may include a solution of a polar aprotic solvent, such as dimethyl sulfoxide, benzyl alcohol and ethanol. | 09-18-2014 |
| 20140271905 | Neural Progenitor Cell Differentiation - Differentiation and stability of neural stem cells can be enhanced by in vitro or in vivo culturing with one or more extracellular matrix (ECM) compositions, such as collagen I, IV, laminin and/or a heparan sulfate proteoglycan. In one aspect of the invention, adult mammalian enteric neuronal progenitor cells can be induced to differentiate on various substrates derived from components or combinations of neural ECM compositions. Collagen I and IV supported neuronal differentiation and extensive glial differentiation individually and in combination. Addition of laminin or heparan sulfate to collagen substrates unexpectedly improved neuronal differentiation, increasing neuron number, branching of neuronal processes, and initiation of neuronal network formation. In another aspect, neuronal subtype differentiation was affected by varying ECM compositions in hydrogels overlaid on intestinal smooth muscle sheets. The matrix compositions of the present invention can be used to tissue engineer transplantable innervated GI smooth muscle constructs to remedy aganglionic disorders. | 09-18-2014 |
| 20140271906 | NGNA COMPOSITIONS AND METHODS OF USE - The present invention relates to the field of viral disorders, and in particular to viral obesity. Compositions comprising nutraceutical agents are provided for treating viral obesity. Additionally, compositions comprising nutraceutical agents targeting adenoviruses are provided. | 09-18-2014 |
| 20140314869 | ISOLATING AND THERAPEUTIC USE OF PERIVASCULAR MEDICINAL CELLS - Disclosed are perivascular medicinal cells (PVMCs), methods of isolating PVMCs, and a composition comprising PVMCs having medicinal capabilities. Specifically, the disclosure provides a method of isolating PVMCs from an umbilical cord blood vessel or from bone. The disclosure further provides a method of making an enhanced, autologous bone graft, a method of stimulating bone regeneration comprising administering a therapeutically effective amount of bone-derived PVMCs, a method of reconstructing bone tissue, and methods of treating a disease that affects cellular function. PVMCs capable of secreting a site-dependent trophic factor are also described. | 10-23-2014 |
| 20140342008 | PERSONAL CARE SUBSTANCES HAVING CERTAIN MINERAL AND ORGANIC BASED CONSTITUENT MATERIALS - Skin care creams and atomizable liquids, based on mineral based ingredients such as those in gemstones and gold, and organically based ingredients such as organic solvents, eggs, and others. The personal care substances are in fluid form, including a carrier fluid together with active ingredients. The final fluids may be topically applied, or may be used as additives to other personal care substances. | 11-20-2014 |
| 20140356446 | Apparatus And Method For Separating and Concentrating Fluids Containing Multiple Components - An apparatus may allow separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample and mesenchymal stem cells from bone reaming material. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. | 12-04-2014 |
| 20150064269 | METHOD FOR PRODUCING DRY EARTHWORM POWDER - [Task] A method for producing dry earthworm powder, in which there is no risk of reduction of the enzymatic activity of earthworms and the enzymatic activity of the dry earthworm powder obtained therefrom is increased, is provided. | 03-05-2015 |
| 20150079190 | Immortalized cell compositions and compositions derived therefrom - The invention is directed to immortalized cell compositions and compositions derived therefrom. The invention is further directed to methods of making and using such immortalized cell compositions and compositions derived therefrom. Such immortalized cell compositions include but are not limited to Immortalized Amnion-derived Multipotent Progenitor cells (herein referred to as I-AMP cells) and conditioned media derived therefrom (herein referred to as I-Amnion-derived Cellular Cytokine Solution or I-ACCS). | 03-19-2015 |
| 20150104522 | USE OF PHARMACEUTICAL COMPOSITIONS IN PREPARING PHARMACEUTICALS FOR TREATING DIABETIC ULCER - This invention relates to use of pharmaceutical compositions in preparing pharmaceuticals for treating diabetic ulcer in limb or on body surface, or in preparing medical dressing. The pharmaceutical compositions consist of (A) 3 to 15% by weight of edible beeswax and (B) 85 to 97% by weight of sesame oil extract of Huangqin, Huanglian, Huangbai, earthworm and poppy capsule, based on the total weight of the pharmaceutical compositions. In the sesame oil extract, each of Huangqin, Huanglian, Huangbai, earthworm and poppy capsule is in an amount of 2 to 10% by weight of dry raw material based on the total weight of sesame oil. This invention also relates to a medical dressing for treating diabetic ulcer and corresponding medicine box enclosing the said dressing. | 04-16-2015 |
| 20150132401 | Methods and Compositions for Treating Skin - A method for treating intact irritated or inflamed skin with a composition comprising at least one Histamine Receptor pathway inhibitor; at least one Lipoxygenase pathway inhibitor; at least one Cyclooxygenase pathway inhibitor and at least one Chemotaxis pathway inhibitor. | 05-14-2015 |
| 20150140112 | COMPOSITION COMPRISING EXTRACT OF MIXTURE OF UNDARIA PINNATIFIDA SPOROPHYLLS AND ASCIDIAN SHELLS FOR TREATING ATOPIC DERMATITIS - The present invention relates to a composition comprising an extract of a mixture of | 05-21-2015 |
| 20150299650 | USE OF STEM CELL CONDITIONED MEDIUM TO INHIBIT OXIDATION FOR ANTI-AGING SKIN - A use of a stem cell conditioned medium to inhibit oxidation for anti-aging skin. First, mesenchymal stem cells are cultured in a cell culture dish containing a complete growth medium. After mesenchymal stem cells are sub-cultured in the complete growth media for three times and transferred to a basal medium, a conditioned medium can be acquired from the basal medium. | 10-22-2015 |
| 20150376185 | N1-PYRAZOLOSPIROKETONE ACETYL-CoA CARBOXYLASE INHIBITORS - The invention provides a compound of Formula (I) | 12-31-2015 |
| 20160008268 | PORE MINIMIZER | 01-14-2016 |
| 20160038556 | HEALTHCARE FOOD WITH ANTI-DIABETIC EFFECT AND PREPARATION METHOD THEREOF - A healthcare foodstuff having an anti-diabetic effect and effective for treating type 2 diabetes mellitus. The healthcare foodstuff comprises effective ingredients and adjuvant(s), including | 02-11-2016 |
| 20160058696 | ORIENTAL MEDICINAL COLLAGEN FOOD AND MANUFACTURING METHOD THEREOF - Oriental medicinal collagen food and manufacturing method of the oriental medicinal collagen food for skin beauty enhancement are provided. The manufacturing method including: a first process including: removing claws and scales from chicken feet, and preparing dandelion, | 03-03-2016 |
| 20160058802 | DERMAL COMPOSITIONS CONTAINING GORGONIAN EXTRACT - A skincare composition comprising Gorgonian extract as an anti-inflammatory component thereof, said skincare composition being selected from among compositions (I) and (II): (I) an aqueous composition comprising from 35 to 65 wt. % water, from 25 to 45 wt. % surfactant, from 0.01 to 0.2 wt. % retinol and from 0.005 to 0.5 wt. % Gorgonian extract, wherein all weight percentages are based on total weight of the aqueous face wash composition, and all weight percentages of all ingredients in the aqueous face wash composition total to 100 wt. %; and (II) a gel composition comprising from 60 to 90 wt. % water, from 1 to 12 wt. % benzoyl peroxide, and from 0.05 to 1.25 wt. % Gorgonian extract, wherein all weight percentages are based on total weight of the gel composition, and all weight percentages of all ingredients in the gel composition total to 100 wt. %. | 03-03-2016 |
| 20160074457 | COMPOSITION FROM SPHAERANTHUS INDICUS AND GARCINIA MANGOSTANA FOR THE CONTROL OF METABOLIC SYNDROME - Pharmaceutical/dietary supplements and food ingredient(s) derived from | 03-17-2016 |
| 20160106795 | Methods and Compositions for Treating Skin - A method for treating intact irritated or inflamed skin with a composition comprising at least one Histamine Receptor pathway inhibitor; at least one Lipoxygenase pathway inhibitor; at least one Cyclooxygenase pathway inhibitor and at least one Chemotaxis pathway inhibitor. | 04-21-2016 |
| 20160108368 | EXOSOMES FROM CLONAL PROGENITOR CELLS - The invention provides methods, compositions, uses and kits relating to exosomes isolated from progenitor cells. | 04-21-2016 |
