| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 424528000 | Bile, bile acid, bile salt, amniotic fluid, or ascitic fluid | 9 |
| 20080286378 | Use of Amniotic Fluid (Af) in Treating Ocular Disease and Injury - Compositions and methods for the treatment of ocular disease and injury are provided. The methods involve the administration of amniotic fluid directly to the eye, for example, as eye drops. The types of diseases and injuries that can be treated in this manner include chemical burns, dry eye and corneal neovascular disorders, corneal opacities (including corneal haze) and inflammatory diseases of the eye. | 11-20-2008 |
| 20100003339 | FERTILITY AGENT - Means for improving the success rate of pregnancy on the basis of blastocyst transfer is disclosed. The means comprises an agent for promoting pregnancy in blastocyst transfer comprising the supernatant of the culture which is obtained by culturing a human embryo in a medium until the embryo develops into a blastocyst. Also disclosed are a method for production of the agent, as well as a method for promoting pregnancy comprising: culturing a human embryo in a medium until the human embryo develops into a blastocyst, injecting a composition comprising the supernatant of the culture into the uterine cavity of a patient who is to undergo blastocyst transfer, and then transferring the blastocyst to the recipient. | 01-07-2010 |
| 20110038944 | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF HEPATOBILIARY DISEASE AND ASSOCIATED DISORDERS - Provided are nucleic acids comprising ABCB4 gene mutations (e.g., insertions, deletions, frame shift, missense) (e.g., canine ABCB4 1583_1584G) that result in prematurely terminated and/or inactive ABCB4 proteins. A significant association (P=1.54E-7) of the mutations was detected between gallbladder mucoceles-affected dogs, providing methods for detection or diagnosis of a hepatobiliary disease and/or related conditions (e.g., increased mucin secretion, mucinous hyperplasia, gallbladder mucocele, progressive familial intrahepatic cholestasis (type 3), cholelithiasis, primary biliary cirrhosis, and intrahepatic cholestasis of pregnancy). Compositions and methods for genotyping or screening of test subjects are provided, and have added utility in combination with surgical intervention, selective breeding, and medical or dietary management. Also provided are methods of treatment of dogs with hepatobiliary disease, comprising administration of hydrophilic, less cytotoxic bile acids (e.g., ursodeoxycholate). Methods for screening or testing for therapeutic agents for treatment of human hepatobiliary disease, comprising use of canine test subjects harboring ABCB4 gene mutations are provided. | 02-17-2011 |
| 20110111047 | COMBINATION PREPARATION OF A BIOLOGICAL RESPONSE MODIFIER AND AN ANTICANCER AGENT AND USES THEREOF - The present invention provides anticancer biological response modifier combinations. In accordance with an aspect of the present invention, there is provided a combination comprising: (i) a composition comprising small molecular weight components of less than 3000 daltons, and having the following properties: is extracted from bile of animals; is capable of stimulating monocytes and/or macrophages in vitro and/or in vivo; is capable of modulating tumor necrosis factor production and/or release; contains no measurable level of IL-1α, IL-1β, TNF, IL-6, IL-8, IL-4, GM-CSF or IFN-gamma; is not cytotoxic to human peripheral blood mononuclear cells; is not an endotoxin; and (ii) one or more anticancer agent(s), wherein said combination has therapeutic synergy or improves the therapeutic index in the treatment of cancer over the composition or the anticancer agent(s) alone. Another aspect of the present invention provides the use of this combination in the manufacture of a medicament or a pharmaceutical kit and in the treatment of cancer. | 05-12-2011 |
| 20130045278 | SKIN FORMULATION, PREPARATION AND USES THEREOF - Serum compositions for application to skin are described which contain an amniotic fluid extract in combination with embryonic stem cells. Formulations containing the serum composition are also described. The serum compositions and formulations may be applied to skin for treatment of symptoms of aging, wounds, burns, scars or other skin lesions. Methods of preparing the serum compositions and formulations are also disclosed. | 02-21-2013 |
| 20130052272 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER - The present invention concerns pharmaceutical compositions and methods for treating proliferative diseases, e.g. cancer using intracellular and extracellular extracts. These cell extracts can direct epigenetic reprogramming of the cancer cells and thereby reverse their neoplastic phenotype | 02-28-2013 |
| 20140079797 | SKIN FORMULATION, PREPARATION AND USES THEREOF - Serum compositions for application to skin are described which contain an amniotic fluid extract in combination with embryonic stem cells. Formulations containing the serum composition are also described. The serum compositions and formulations may be applied to skin for treatment of symptoms of aging, wounds, burns, scars or other skin lesions. Methods of preparing the serum compositions and formulations are also disclosed. | 03-20-2014 |
| 20140093582 | FORMULATION FOR TREATMENT OF DRY MOUTH AND MOUTH SORES - Serum compositions for application to endothelial tissue are described which contain an amniotic fluid extract in combination with embryonic stem cells. Formulations containing the serum composition are also described. The serum compositions and formulations may be used to treat conditions of the mouth such as dry mouth and mouth sores. | 04-03-2014 |
| 20150140114 | SKIN TREATMENT PROTOCOL UTILIZING AMNIOTIC SOLUTION - A skin treatment method, including: performing a skin treatment procedure on the skin of a patient, wherein the skin treatment procedure includes one of a chemical peel procedure, a dermabrasion procedure, a micro-needling procedure, and a laser procedure; and subsequently, applying a preparation including one or more of amniotic fluid and amniotic membrane material to the treated skin of the patient to promote healing and collagen rejuvenation, wherein the preparation including the one or more of amniotic fluid and amniotic membrane material is prepared from one or more of amniotic fluid, a concentrated amniotic membrane solution, and an amniotic membrane powder. The preparation comprising the one or more of amniotic fluid and amniotic membrane material also includes sterile water or saline. The treated skin of the patent preferably includes one or more of the skin of the face and the skin of the neck. | 05-21-2015 |
