Class / Patent application number | Description | Number of patent applications / Date published |
422056000 | Having reagent in absorbent or bibulous substrate | 29 |
20090196792 | Multiple Assay Device - Disclosed is an assay device for the determination of analyte in a liquid sample over an extended concentration range comprising a first assay and a second assay, wherein the first assay for an analyte comprises a first flow-path having a sole detection zone capable of immobilising a labelled binding reagent and the second assay for said analyte comprises a second flow-path having a sole detection zone capable of immobilising a labelled binding reagent, wherein the presence of labelled binding reagent at the detection zones provides an indication of the presence and/or extent of analyte in said liquid sample. | 08-06-2009 |
20090191093 | BIOCHEMICAL TEST STRIP - A biochemical test strip is provided. The biochemical test strip includes an insulating substrate, an electrode system, an insulating layer, and a cover. The electrode system is formed on the insulating substrate and the insulating layer is formed on the electrode system. The insulating layer has an opening, and the opening exposes a part of the electrode system to define a reaction region with a supply port. The cover is formed above the insulating layer to cover the reaction region and has a slot corresponding to the reaction region and a sampling hole corresponding to the supply port. | 07-30-2009 |
20100074800 | OZONE DETECTING DEVICE | 03-25-2010 |
20100239458 | COLLECTION DEVICE FOR ASSAY OF ORAL FLUIDS - An apparatus and process for transporting aqueous fluid from the oral cavity to a lateral chromatographic strip for test is disclosed. A lateral chromatographic strip is placed within a cavity defined in a housing. The lateral chromatography strip extends within the cavity and is disposed along the housing to an inspection site. At least one inspection site to the lateral chromate phic strip is provided to enable inspection of selected sites on the lateral chromatographic strip for test results. A porous wick material protrudes from the housing to a collection site exterior of the housing at one end and communicates to the lateral chromatographic strip at the other end. This porous wick material has particulate construction, the particles adsorbing aqueous oral fluid to transport the fluid from the mouth to the lateral chromatographic strip without substantial absorption. The particles of the porous wick material are bound together to define a continuous interstitial volume for the flow of oral fluid to be transported and are treated to be hydrophilic to the adsorbed oral fluids. The porous wick material readily releases oral fluid to the lateral chromatographic strip. Prevention of reverse flow to the oral cavity from the lateral chromatographic strip naturally occurs due to the circuitous flow path of the porous wick material. By observing the lateral chromatographic strip while the entire test device is in the mouth immediate test results are obtained. | 09-23-2010 |
20090148344 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS - The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being. | 06-11-2009 |
20100098583 | Blood Glucose Tracking Apparatus and Methods - A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand-held computer. Electronics determine the amount of glucose present in a sample of body fluid, when the test strip is positioned in the receptacle and the body fluid is placed on a test strip, and communicate the glucose amount to the hand-held computer via the connector portion. | 04-22-2010 |
20080310998 | Liquid Flow Assays Utilising a Combined Detection and Control Zone - The invention relates to liquid flow assays widely applicable to target analytes, including haptens, which employ a detection zone which is a single combined analyte detection and control zone in a test strip or sheet and two labelled reagents with detectably distinguishable labels, preferably with visually contrasting coloured particle labels, whereby both negative and positive samples are distinguishable by detection of different captured label signals in the detection zone. | 12-18-2008 |
20090123334 | Device and Method for Monitoring the Temperature to Which a Product has Been Exposed - A device for monitoring the temperature to which a product has been exposed, comprising at least one spatially structured element, constituted by a material indicating a preset level of temperature and a preset exposure time interval, and adapted to be applied to a monitored product. The indicator material is selected among materials which detectably change their morphological and/or structural and/or chemical and/or physical state once the material is placed in a condition in which it can absorb a preset amount of heat. | 05-14-2009 |
20090311142 | DEVICE FOR RAPID DETERMINATION OF DISEASE-ASSOCIATED THIOL COMPOUNDS - Disclosed is a single-use disposable article for determining the concentration of thiol compounds in a sample of fluid, and a description of how to make and use the article. | 12-17-2009 |
20090311141 | IMMUNOCHROMATOGRAPHIC STRIP FOR USE IN IMMUNOASSAY AND KIT COMPRISING THE SAME - The present invention relates to an immunochromatographic strip and a kit comprising the same. The immunochromatographic strip according to the present invention is characterized in that it comprises a) an adhesive plastic backing, b) a sample pad receiving a liquid sample to be analyzed, which is attached on the surface of the top portion of the adhesive plastic backing, a conjugate pad coupled to the sample pad, which contains a conjugate specifically binding to an analyte in the liquid sample from the sample pad, d) a signal detection pad coupled to the conjugate pad, which comprises a signal detection zone to detect the presence of the analyte in the liquid sample and a control zone to confirm whether the liquid sample chromatographically migrates regardless of the presence of the analyte, and e) an absorbent pad positioned downstream of the signal detection pad, which absorbs the liquid sample after the completion of the signal detection reaction and comprises a porous backing and an absorbent dispersed, adsorbed, or coated into the pores of the porous backing. It is more preferable that the absorbent pad further comprises a film layer attached on the top portion of the porous backing. It is most preferable that the film layer attached on the top portion of the porous backing is a porous membrane. The absorbent pad having the above-described structure efficiently absorbs the liquid sample after the completion of the signal detection reaction. As a result, the chromatographic flow is improved, test errors caused by the backflow of liquid sample are reduced, background clearance is improved, and the result of signal detection is consistently maintained. More significantly, with the help of the absorption ability improved by the absorbent which is dispersed into the porous backing, more preferably adsorbed, or coated onto fibers of the porous backing, the immunochromatographic strip and kit comprising the same absorb moisture in air quickly and sufficiently. Thus, in addition to improved performance, there is no need to package the strip or the kit with an additional absorbent bag in a pouch, which makes the packaging process simple, thereby improving the speed of automatic packaging process. | 12-17-2009 |
20090214384 | IDENTIFICATION OF A STRIP TYPE BY THE METER USING CONDUCTIVE PATTERNS ON THE STRIP - A test strip including a reagent end for receiving a body fluid sample and an insertion end which is received at a test strip receptacle slot of a measuring device, the insertion end including one or more on-strip indicators for indicating to a measuring device that the test strip has been inserted into the device so that the device will power-up in preparation to perform a test, and the one or more on-strip indicators having a distinct pattern indicating whether calibration is automatic or whether the user needs to input calibration information to the said device, and corresponding methods are disclosed. | 08-27-2009 |
20090246078 | Electromagnetic Assay - An apparatus includes a sample strip-receiving member configured to receive a sample strip that includes a chamber. The chamber includes a magnetically susceptible particle. The apparatus also includes an electromagnetic field generator configured to subject the magnetically susceptible particle of the chamber of a sample strip received by the sample strip-receiving member to an oscillating magnetic field. The electromagnetic field generator includes first and second coils. The coils are spaced apart along and disposed about a common axis. A detector is configured detect a response to the oscillating magnetic field of the particle of a chamber of a received sample strip. The device can be used to, for example, determine a coagulation parameter of a blood sample. | 10-01-2009 |
20100111763 | Examination Device for Blood Detection - The present invention describes examination devices, such as examination gloves, for detecting the presence of blood, and in particular hidden blood, in biological samples. Examination devices according to the present invention include, in certain embodiments, developer and indicator reagents in a single encapsulation and in microencapsulations, which offers numerous clinical and other benefits. Kits including devices according to the present invention in sterile packaging, and methods of making and using devices according to the present invention, are also described. | 05-06-2010 |
20100196200 | BIOLOGICAL TEST STRIP - A biological test strip is disclosed and includes a source end, at least one test line and at least two control lines. The source end is used for dropping a sample liquid thereon. The at least one test line is used to react with at least one sample of the sample liquid to generate a colorization reaction. The at least two control lines are used to react with the sample liquid to generate at least two colorization reactions with different color darkness, so as to define a predetermined maximum concentration value and a predetermined minimum concentration value, both of which can be used as color comparison references for the at least one test line. | 08-05-2010 |
20090214383 | ASSAY TEST STRIPS WITH MULTIPLE LABELS AND READING SAME - In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described. | 08-27-2009 |
20100178203 | Non-Invasive Colorimetric-Based Infection Detector And Infection Detecting Bandage - A non-invasive, calorimetric infection detector is provided, comprised of a substrate, and one or more indicator compositions disposed upon or incorporated therein. These indicator compositions exhibit a persistent change color when exposed to gaseous oxides of nitrogen and acids formed therefrom, providing a means of detecting NO production in a wound, which has been found to occur at a high level at the onset of infection in a wound. In addition, a bandage is provided, comprised of the detector, as well as a porous portion, and preferably a hydrophobic barrier layer to protect the detector from contamination by water and other fluids draining from the wound. The non-invasive, calorimetric infection detector, and bandage containing same, can be utilized to provide a convenient, easily utilized colorimetric means of detecting the onset of wound infection, thereby enabling caregivers to effectively and timely treat infections. | 07-15-2010 |
20080267821 | Test Piece for Analysis - The present invention provides an analytical test piece | 10-30-2008 |
20100068093 | Identification of a Strip Type by the Meter Using Conductive Patterns on the Strip - A test strip including a reagent end for receiving a body fluid sample and an insertion end which is received at a test strip receptacle slot of a measuring device, the insertion end including one or more on-strip indicators for indicating to a measuring device that the test strip has been inserted into the device so that the device will power-up in preparation to perform a test, and the one or more on-strip indicators having a distinct pattern indicating whether calibration is automatic or whether the user needs to input calibration information to the said device, and corresponding methods are disclosed. | 03-18-2010 |
20100209296 | Combination Rapid Detection Cartridges For Biological and Environmental Agents, Methods of Production and Uses Thereof - Hand-held test cartridges are described herein that comprise at least one assay, where each assay can simultaneously test for at least two different types of biological agents, environmental agents or combinations thereof. Methods of measuring biological and environmental agents are described herein that include: providing at least one multicomponent hand-held test cartridge, wherein the cartridge has multiple channels for testing multiple agents, providing at least two biological agents, environmental agents or a combination thereof, applying the at least two biological agents, environmental agents or a combination thereof to the multicomponent test cartridge, such that the biological and/or environmental agent is applied to the appropriately labeled section of the cartridge. | 08-19-2010 |
20080286148 | PH INDICATOR - A pH indicator comprising a solid substrate coated at least partially by at least one layer of at least one substance, wherein said the and the substrate are having different colors and wherein the at least one substance is selected to dissolve or to decompose when exposed to predetermined pH values, thereby exposing said first color. | 11-20-2008 |
20090257915 | PREWETTING LATERAL FLOW TEST STRIP - A test strip and method for detecting an analyte present in a sample. The test strip comprising: a buffer addition zone to which a buffer may be added; an absorbent zone proximal to the buffer addition zone; one or more test zones distal to the buffer addition zone, at least one of the test zones including a first analyte binding agent immobilized therein which is capable of binding to the analyte to be detected; a terminal buffer flow zone distal to the one or more test zones, the absorbent zone being positioned relative to the buffer addition zone and having an absorption capacity relative to the other zones of the test strip such that when a volume of buffer within a predetermined buffer volume range for the test strip is added to the buffer addition zone, a distal diffusion front of the buffer diffuses from the buffer addition zone to a distal diffusion point within the terminal buffer flow zone and then diffuses proximal relative to the one or more test zones; and a sample addition zone distal to the terminal buffer flow zone to which a sample may be added. | 10-15-2009 |
20100290948 | ABSORBENT ARTICLES CAPABLE OF INDICATING THE PRESENCE OF URINARY TRACT INFECTIONS - In accordance with one embodiment of the present disclosure, a diagnostic test kit for detecting the presence or absence of nitrites within a test sample is disclosed. The test kit comprises an aromatic primary amine that is capable of reacting with a nitrite to form a diazonium ion. The test kit also comprises a lateral flow device that comprises a chromatographic medium and an absorbent material that receives the test sample after flowing through the chromatographic medium. The chromatographic medium defines a detection zone within which is contained a detection reagent consisting of a nucleophilic aromatic amine that is directly bound through covalent bonding to the chromatographic medium. The detection reagent is capable of reacting with the diazonium ion to form an indicator (e.g., azo compound). The indicator exhibits a color that is different than the color of the detection reagent. | 11-18-2010 |
20100209295 | ASSAY DEVICES AND METHODS AND COMPONENTS FOR USE THEREIN - Dipsticks and other assay devices suitable for the assay of haptens are disclosed. Also disclosed are blocking agents for use in such devices. | 08-19-2010 |
20090081080 | DIAGNOSTIC DEVICES FOR USE IN THE ASSAYING OF BIOLOGICAL FLUIDS - Diagnostic in-vitro devices for use in the assaying of biological fluids are provided which include cover plates or backing strips which exhibit hydrophilic properties to assist in transport of the biological fluid or retention of same within the device. Exemplary diagnostic devices include lateral flow devices, microfluidic devices and microtiter plates. The devices may also be comprised of low fluorescent material in order to facilitate any diagnostic determination by use of fluorescent emissions. Hydrophilic properties may be imparted to the cover plates or backing strips by physical or chemical treatment thereof. The cover plates or backing strips may exhibit heat sealable or pressure sensitive properties. | 03-26-2009 |
20080299005 | DISINTEGRATABLE FILMS FOR DIAGNOSTIC DEVICES - The invention provides disintegratable film compositions for diagnostic test devices. The films are prepared with a combination of components that yield films of sufficient film strength and desired disintegration profiles. A disintegratable film according to the present invention contains a water soluble high molecular weight component, a water soluble low molecular weight component, and one or more reagents for use in a diagnostic device. Optionally, the films further contain a starch component, a glucose component, a plasticizer and/or a humectant, and/or a filler. The invention further provides a diagnostic testing device, which includes a film according to an embodiment of the invention, and methods of using such devices. | 12-04-2008 |
20090074612 | Gas Sorption Tester For Rapid Screening of Multiple Samples - An apparatus determines gas sorption properties of a large number of material samples simultaneously. The apparatus includes a switchable manifold of low-volume conduits and an array of sensors, where each low-volume conduit fluidly couples a single sample of gas-sorbing material to a dedicated detector. The switchable manifold is also configured to fluidly couple the samples to a vacuum source or a dosing gas source. Because of the very low internal volume of the conduits, essentially all gas released from a particular sample is accurately detected by the corresponding detector, either through sorption of the released gas, by measuring pressure, or by other means. In this way, a very accurate measurement of the quantity of gas released by the sample is made. In one embodiment, the array of sensors includes hydride-based sensors, which contain a material that forms an optically and/or electrically responsive hydride upon exposure to hydrogen-containing gas. | 03-19-2009 |
20090317297 | ANALYTE TEST STRIP FOR ACCEPTING DIVERSE SAMPLE VOLUMES - An analyte test strip for accepting diverse bodily fluid sample volumes includes a first insulating layer, a second insulating layer disposed above the first insulating layer, and a third insulating layer disposed below the first insulating layer. The third insulating layer has a platform portion that extends beyond the first and second insulating layers and an upper surface. The analyte test strip also has a patterned spacer layer positioned between the first and second layers. The patterned spacer layer defines a channel between the first and second insulating layers that has a sample-receiving chamber, a first port proximate the platform portion and a second port at an outer edge of the analyte test strip. Moreover, the first port and the second port are in fluidic communication with the sample-receiving chamber. In addition, the upper surface of the platform portion is configured to receive a first (relatively large) bodily fluid sample of at least 5 micro-liters and transfer at least a portion of the first bodily fluid sample to the sample-receiving chamber via the first port. The second port is configured to receive a second (relatively small) bodily fluid sample of lesser volume than the first bodily fluid sample and to transfer at least a portion of the second bodily fluid sample to the sample-receiving chamber. | 12-24-2009 |
20100124516 | APPARATUS FOR DETERMINING TOTAL CHLORINE IN LIQUIDS - The present invention relates to an apparatus for determining total chlorine in liquids, the apparatus comprising an indicator carrier that is impregnated with a color indicator that contains Michler's thioketone, the indicator carrier additionally containing as a color indicator at least one azine as well as an iodide, in particular potassium iodide and/or sodium iodide. | 05-20-2010 |
20090232702 | TEST DEVICE FOR DETECTING AN ANALYTE IN A LIQUID SAMPLE - The present invention relates to test devices, and in particular devices capable of detecting the presence or absence of an analyte in a sample, such as a liquid sample. Also provided are methods of using such devices for quantitative or qualitative measurement of one or more analytes in a liquid sample. | 09-17-2009 |