| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 204602000 | With control means responsive to sensed condition | 14 |
| 20100000866 | MICROFLUIDIC DEVICE FOR CONTROLLED MOVEMENT OF LIQUID - The invention concerns a microfluidic device for the controlled movement of liquid. | 01-07-2010 |
| 20100032298 | Method of Cell Capture - Embodiments of methods and devices are disclosed for the manipulation (e.g., concentration, purification, capture, trapping, location, transfer) of analytes, e.g., biomolecules, with respect to analyte-containing solutions, using one or more electric fields. | 02-11-2010 |
| 20100170799 | MULTI-CAPILLARY ELECTROPHORESIS CARTRIDGE INTERFACE MECHANISM - The present invention provides for an interface mechanism in a bio-separation instrument that makes interface connections to a multi-channel cartridge. The interface mechanism precisely positions the cartridge in relation to the support elements in the instrument (e.g., high-voltage, gas pressure, incident radiation and detector), and makes automated, reliable and secured alignments and connections between various components in the cartridge and the support elements in the supporting instrument. The interface mechanism comprises pneumatically or electromechanically driven actuators for engaging support elements in the instrument to components on the cartridge. After the cartridge has been securely received by the interface mechanism, the connection sequence is initiated. The interface provides separate high voltage and optical connections for each separation channel in the cartridge, thus providing channel-to-channel isolation from cross talk both electrically and optically. | 07-08-2010 |
| 20100252437 | OPTICAL DETECTION ALIGNMENT COUPLING APPARATUS - An apparatus for aligning a capillary column with one or more excitation fibers and with one or more optical lens elements for Capillary Electrophoresis. The apparatus includes two identical blocks having a plurality of grooves for positioning and aligning the capillary column with the one or more excitation fibers, and a plurality of lens seats for optically coupling the lens element with the capillary column. Each block includes a male and female part for mating the two identical blocks together. | 10-07-2010 |
| 20120043211 | CAPILLARY ELECTROPHORESIS APPARATUS - Provided is a capillary electrophoresis apparatus capable of avoiding electric discharge even when a conductive component is arranged near a cathode end of a capillary. The capillary electrophoresis apparatus of the present invention has a structure in which a spatial distance and a creeping distance between an electrode attached to the cathode end of the capillary and the conductive component are large even when the conductive component is arranged near the cathode end of the capillary. That is to say, the capillary electrode, which protrudes from a lower surface of the load header, penetrates through a space between the load header and an anti-evaporation film and further penetrates through a capillary hole formed on the anti-evaporation film to extend into a container. At least a portion exposed to the space between the load header and the anti-evaporation film of the capillary electrode is covered with an insulating member. | 02-23-2012 |
| 20120080315 | FLUIDIC DEVICES HAVING INCORPORATED ELECTRODES - The invention provides fluidic devices having incorporated electrodes, systems for using such devices, and methods for manufacturing such devices. The invention also provides fluidic devices configured to absorb joule heating within the device. | 04-05-2012 |
| 20120103816 | MULTI-TASK IMMUNOAFFINITY DEVICE SECURED TO A PERIPHERAL BOX AND INTEGRATED TO A CAPILLARY ELECTROPHORESIS APPARATUS - The present invention relates to an immunoaffinity device for capturing one or more analytes present at high or low concentrations in simple or complex matrices. The device is designed as a modular, multi-task immunoaffinity device secured to a peripheral box and connected to capillary electrophoresis or liquid chromatography for the isolation, enrichment, separation and identification of polymeric macromolecules, primarily protein biomarkers. In one embodiment, two devices are coupled in-tandem to perform separately and sequentially microreactions and concentrations of proteins. In this embodiment, biological samples containing proteins can be subjected to proteolytic processing in the first device, and the resulting peptides subjected to selective purification and concentration in the second device. | 05-03-2012 |
| 20120298511 | CHANNEL DEVICE AND SAMPLE TREATMENT APPARATUS INCLUDING THE SAME - A channel device including a nanosize channel through which single molecule flows, at least one electrode pair arranged near the nanosize channel, and an AC power source that applies an AC voltage to the electrodes. This channel device is useful for identifying molecules one by one. Furthermore, a channel device including a nanosize channel through which single molecule flows, a branching portion, and a plurality of branching channels, wherein (i) an electrode pair is arranged near the nanosize channel so as to sandwich the nanosize channel between the electrodes, or (ii) one electrode of the electrode pair is located near the nanosize channel, whereas the other is arranged near the branching channels. This channel device is useful for separating single molecule. The present channel device achieves identification or separation at an accuracy of 100% in principle. A sample treatment apparatus according to present invention includes a channel device, a measurement section, and an arithmetic processing section. The measurement section applies a voltage (DC or AC) to between electrodes of an electrode pair installed in the nanosize channel, and measures an electric signal when single molecule passes between the electrodes to identify the molecule | 11-29-2012 |
| 20130199933 | Ruggedized Apparatus for Analysis of Nucleic Acid and Proteins - The invention provides methods and systems for ruggedizing a nucleic acid analyzing apparatus. The ruggedized apparatus can be used reliably and effectively in uncontrolled environments, such as, for example at a crime scene to collect and analyze forensic data, as well as in semi-controlled environments, such as, for example at a point of care location. | 08-08-2013 |
| 20150027892 | MANIPULATION OF MICROFLUIDIC DROPLETS - The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control. | 01-29-2015 |
| 20150377829 | CAPILLARY UNIT FOR ELECTROPHORESIS AND ELECTROPHORESIS DEVICE COMPRISING THE CAPILLARY UNIT - A capillary unit includes a reservoir capable of retaining a liquid. A capillary having a linear shape has one end secured on a bottom-end portion of the reservoir. The capillary extends from the bottom-end portion in a direction away from an opening of the reservoir. A nozzle connector is provided between a bottom of the reservoir and the one end of the capillary, and provides liquid-tight removable connection with a nozzle for injecting the liquid into the capillary from a portion adjacent to the reservoir. | 12-31-2015 |
| 20160059230 | BIOCHIP PACKAGE - A biochip package includes: (a) a bottom plate including a bottom substrate, a first electrode layer disposed on the bottom substrate and a first hydrophobic layer disposed on the first electrode layer; (b) a top plate including a top substrate and a second hydrophobic layer disposed on the top substrate, wherein the first hydrophobic layer and the second hydrophobic layer are oppositely disposed and spaced from each other to form a liquid channel; (c) a control unit connected to the first electrode layer for operating a fluid in a first direction; (d) at least one biochip disposed over the bottom plate by connecting pillars to allow the fluid to flow between the at least one biochip and the bottom plate. | 03-03-2016 |
| 20160074863 | MICROFLUIDIC FEEDBACK USING IMPEDANCE DETECTION - Methods comprising measuring the impedance of the electrode produced by the excitation signal, wherein the impedance indicates presence of liquid at the electrode are disclosed. Computer readable mediums storing processor executable instructions for performing the method, and systems are also disclosed. The systems comprise a processor, memory and code stored in the memory that when executed cause the processor at least to: receive an output voltage signal, superimpose an excitation signal onto the output voltage signal to produce a superimposed signal, connect the superimposed signal to an electrode in a droplet actuator, suppress the output voltage signal, when detecting an impedance of the electrode, and measure the impedance of the electrode produced by the excitation signal, wherein the impedance indicates presence of liquid at the electrode. | 03-17-2016 |
| 20160195492 | Droplet Operations Platform | 07-07-2016 |
