Class / Patent application number | Description | Number of patent applications / Date published |
204601000 |
Capillary electrophoresis type
| 166 |
204627000 |
Barrier separator (e.g., electrodialyzer, etc.)
| 96 |
204643000 |
Dielectrophoretic (i.e., uses nonuniform electric field)
| 45 |
204606000 |
Gel electrophoresis type
| 44 |
204622000 |
Coating or forming means | 5 |
20090038945 | Method and device for producing by electrophoresis fully ceramic tooth element having a predefined spatial shape - The invention relates to a method and device for producing by electrophoresis fully ceramic tooth elements having a predefined spatial shape, wherein an electric conductive plate ( | 02-12-2009 |
20100006440 | Apparatus For Electrophoretic Painting Of Metal Objects, In Particular Lids For Containers For Food Use - The apparatus for electrophoretic repainting of metal objects, in particular lids for containers for food use, comprises a tank ( | 01-14-2010 |
20100326832 | Immersion Treatment System - The invention relates to an immersion treatment system, particularly an electrophoretic immersion coating system, comprising at least one immersion basin in a known manner that can be filled with a treatment fluid. A transport system guides the objects to be coated to the immersion basin, into the interior of the immersion basin, out of the immersion basin, and away therefrom. It comprises at least one transport car whereon a vertically displaceable carriage is disposed. A component defining a rotary axis is supported on the same, supporting a mounting device for the object to be treated. A motion sequence for the object can be achieved in said manner, comprising a superposition of a horizontal linear motion, a vertical linear motion, and a rotary motion about the rotary axis. | 12-30-2010 |
20110284380 | Methods for Nanowire Alignment and Deposition - The present invention provides methods and systems for nanowire alignment and deposition. Energizing (e.g., an alternating current electric field) is used to align and associate nanowires with electrodes. By modulating the energizing, the nanowires are coupled to the electrodes such that they remain in place during subsequent wash and drying steps. The invention also provides methods for transferring nanowires from one substrate to another in order to prepare various device substrates. The present invention also provides methods for monitoring and controlling the number of nanowires deposited at a particular electrode pair, as well as methods for manipulating nanowires in solution. | 11-24-2011 |
20140021054 | SYSTEM FOR DIP COATING ARTICLES - A system for dip coating articles, in particular vehicle bodies, which articles can be moved to at least one dip tank and away from it with the aid of a transport system. For being lowered into and raised out of the tank, they are placed onto a rotating platform of at least one stationary rotating station and are dipped into the treatment liquid and removed from it by rotation of the rotating platform. Each article is fastened with the aid of a fastening device on a skid which interacts with the transport system. The fastening device is configured such that the article fastened to the fastening device is at a smaller spacing from the rotating platform in the removed position than in the second, dipped position. | 01-23-2014 |
204641000 |
Absorbent strip (e.g., cellulose acetate, paper strip, etc.) type | 5 |
20090071834 | Methods and Devices for Concentration and Fractionation of Analytes for Chemical Analysis Including Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry (MS) - A device is described for pre-concentration and purification of analytes from biological samples (such as human serum, plasma, homogenized solid tissue, etc.) to be analyzed by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI MS) and methods of use thereof are provided. | 03-19-2009 |
20090127118 | SAMPLE SEPARATION/ADSORPTION APPLIANCE - A sample separation/adsorption appliance ( | 05-21-2009 |
20090260990 | Electroosmotic material, method for production of the material, and electroosmotic flow pump - A porous sintered material is produced which is suitable as an electroosmotic material constituting an electroosmotic flow pump. At least one member selected from BaO, SrO, CaO, TiO | 10-22-2009 |
20110094887 | SAMPLE SEPARATION/ADSORPTION APPLIANCE - A sample separation/adsorption appliance ( | 04-28-2011 |
20110233062 | Biological Molecule Separation Apparatus - A biological molecule separation apparatus for separating a biological molecule of one embodiment of the present invention has a buffer solution chamber receiving a buffer solution, a separation electrode arranged in the buffer solution chamber, a biological molecule separation medium for separating a biological molecule, a biological molecule adsorption film for adsorbing a biological molecule, a pair of transfer electrodes having a plurality of line shaped conductors extending in a direction perpendicular to a first direction, the conductors being arranged in the direction perpendicular to the first direction, and a separation part which holds the transfer electrode, the biological molecule adsorption film, the medium and the transfer electrode, wherein the transfer electrode, the biological molecule adsorption film, the medium and the transfer electrode are stacked in this order. | 09-29-2011 |
204645000 |
Isotachophoretic (i.e., displacement electrophoretic) or means to measure ion or particle mobility | 4 |
20080302666 | APPARATUS FOR DIFFERENTIAL CHARGED-PARTICLE MOBILITY - The invention provides methods of preparation of lipoproteins from a biological sample, including HDL, LDL, Lp (a), IDL, and VLDL, for diagnostic purposes utilizing differential charged particle mobility analysis methods. Further provided are methods for analyzing the size distribution of lipoproteins by differential charged particle mobility, which lipoproteins are prepared by methods of the invention. Further provided are methods for assessing lipid-related health risk, cardiovascular condition, risk of cardiovascular disease, and responsiveness to a therapeutic intervention, which methods utilize lipoprotein size distributions determined by methods of the invention. | 12-11-2008 |
20140209466 | Corrosion resistant electrodes for electrophoretic mobility measurements and method for their fabrication - An electrode for use in instruments capable of measuring the electrophoretic mobility of particles in solution is disclosed. The electrode is comprised of an inexpensive support member, generally made of titanium, onto a flat surface of which has been connected, generally by microwelding, a flat electrically conductive but chemically inert foil member, preferably platinum. A uniform texture can be generated on the exposed surfaces of the electrode by various means including tumbling the electrode with an abrasive. An oxide layer can be generated on the support member by soaking the composite electrode in an appropriate medium, protecting the exposed surface of the support member from fluid contact with the sample solution, while the foil member, unaffected by the oxidation process, is able to contact the sample solution. | 07-31-2014 |
20160139078 | GRADIENT ELUTION ISOTACHOPHORETIC APPARATUS FOR SEPARATING, PURIFYING, CONCENTRATING, QUANTIFYING, AND/OR EXTRACTING CHARGED ANALYTES AND METHODS THEREOF - Gradient elution isotachophoretic apparatus, and systems for performing gradient elution isotachophoresis to separate, purify, concentrate, quantify, and/or extract charged analytes from a sample. The isotachophoretic apparatus include an electrophoretic assembly, a sampling assembly connected to the electrophoretic assembly, and/or a support structure connected to the electrophoretic assembly and/or to the sampling assembly. The system includes an isotachophoretic apparatus, and a controller communicatively coupled to the isotachophoretic apparatus. The controller includes a storage medium and a processor for executing computer readable and executable instructions. | 05-19-2016 |
20160146756 | Magnetohydrodynamic Microfluidic Systems Including Modified Electrodes And Methods Of Using The Same - A magnetohydrodynamic microfluidic system and a method of pumping a fluid using a magnetohydrodynamic system are disclosed. The method includes applying at least one of an electric current and an electric voltage to a first modified electrode and a second electrode to generate an ionic current between the first modified electrode and the second electrode and to cause a current carrying species to move to or from the modified electrode, applying a magnetic field perpendicular to an ionic current vector, the magnetic field and the ionic current combining to induce flow of the fluid in a direction perpendicular to the magnetic field and the ionic current vector, and maintaining fluid flow by recharging the modified electrode. | 05-26-2016 |
204648000 |
Bulk separator for solids and liquids (e.g., to dewater solids, clarify water, etc.) | 3 |
20160144319 | SYSTEM AND METHOD FOR THE CONCENTRATION OF A SLURRY - The present invention relates to a system and a method for the concentration of slurry, especially mineral containing slurry. The invention provides a system comprising an electrophoresis unit and a separation unit, where the separation unit comprises a recipient, preferably of half cylindrical form, with adjusted flanks for separating the solid material or cake from the rotating anodes and a sliding carriage suitable for closing the recipient and stripping resting solid material from the flanks into the recipient before the solid material or cake is pressed out of the recipient by a piston. | 05-26-2016 |
20100089757 | GRADIENT ELUTION ELECTROPHORESIS AND DETECTORLESS ELECTROPHORESIS APPARATUS - A microfluidic apparatus and method for performing electrophoretic separation of compounds. The apparatus comprises: a) A first container for containing a sample fluid; b) a second container for containing a separation buffer fluid; c) a channel of a first length having an inlet end and an outlet end, the inlet end connected to the first container and the outlet end connected to the second container; d) a voltage device electrically connected to the first container and the second container, the voltage device facilitating adjustment of the amount of voltage to the first container and the second container; e) a controller for controlling the velocity flow of the sample fluid through the channel from the first container towards the second container; and f) a measuring device for measuring the current through the channel. The method comprises the steps of: a) providing a separation buffer; b) providing a sample solution in fluid contact with the separation buffer; c) applying an electric field to the separation buffer; and d) producing a variable bulk flow of the separation buffer in a direction substantially aligned with said electric field. Fluid contact between the separation buffer and the sample solution is made through a separation column having a length in the range of from approximately 0.01 mm to approximately 5 mm. By the foregoing, compounds can be sequentially detected and quantified. | 04-15-2010 |
20160046877 | SEQUENTIAL MIXING SYSTEM FOR IMPROVED DESALTING - A system for desalting crude oil includes delivering a stream of salty crude oil and wash water into a mixing valve, mixing the stream of salty crude oil and wash water through the mixing valve to create a mixed stream of desalted crude oil and salty wash water, delivering the mixed stream of desalted crude oil and salty wash water to a static mixer, and mixing the mixed stream of crude oil and wash water in the static mixer. Within the static mixer, the mixed stream is mixed in a coalescing regime to coalesce smaller droplets of water into larger droplets of water. The mixed stream is subjected to an electric field to cause additional coalescence before being directed to a desalter where the salty wash water is separated from the desalted crude oil. | 02-18-2016 |
204644000 |
Isoelectric focusing (i.e., uses pH variation) | 2 |
20090178929 | SEPARATION DEVICE FOR ISOELECTRIC FOCUSING - The invention relates to a device for use in separation, especially isoelectric focusing employing “pH sink regions”, whereby the direction of change in pH is reversed. | 07-16-2009 |
20110132763 | SOLUTION PHASE ELECTROPHORESIS DEVICE, COMPONENTS, AND METHODS - A device for fluid phase electrophoresis, particularly solution phase isoelectric focusing, components thereof, and methods for use are presented. | 06-09-2011 |
204647000 |
Particle bed separator (e.g., inert particles, ion exchange beads, etc.) | 1 |
20120160693 | APPARATUS AND METHOD FOR MANUFACTURING BICHROMAL BALLS - An apparatus for manufacturing bichromal balls including first and second supply containers; a pair of microchannels for moving the first and second liquids; a pair of nozzles at which the microchannels contact each other; and an actuator, and a method for manufacturing bichromal balls using the same. | 06-28-2012 |
Entries |
Document | Title | Date |
20080237046 | Microfluidic device and analyzing device using the same - The conventional micropump and the conventional micromixer have the following problems. In a mechanical or hydrodynamic method, the structure of the inside of a flow path is complex so as to easily cause clogging, and manufacturing cost is high, and dead volume is large. Additionally, in an electrical method, the conventional micropump or the conventional micromixer was incapable of operating with a liquid having the concentration of a physiological saline that is important in the medical or biological field although the structure of the flow path is simple. These problems are solved by applying an AC voltage to a pair of electrodes in which an electrode-to-electrode gap between the pair of electrodes is vertically arranged and by generating the flow of a fluid in the direction opposite to gravity along the electrode-to-electrode gap. A micropump ( | 10-02-2008 |
20080264796 | LATERAL WIRE APPARATUS AND METHOD FOR MONITORING OF ELECTROPHORETIC INK PARTICLE MOTION - A lateral wire apparatus allows direct lateral viewing of particles of electrophoretic ink (e.g., liquid emulsion aggregation particle (LEAP) ink) that are undergoing electrophoretic migration. Electrophoretic ink movement is commonly monitored by placing the ink through the top electrode, but as the toner particles migrate back and forth between the two electrodes, the viewer can not see what lies beneath the top electrode. This may hide commonly known failure modes, such as particle agglomeration, swishing of particles due to hydrodynamic effects. The lateral wire apparatus includes two narrow gauge wires glued to a glass substrate and held apart at a fixed distance to help maintain a uniform electric field across the gap. A plastic block with pegs that situated at a fixed distance and threaded screws is used to make the lateral wire apparatus with precise wire spacing that may be reproducibly made in less than five minutes using inexpensive and readily available materials. | 10-30-2008 |
20080264797 | Apparatus for Manipulating Droplets - An apparatus for manipulating droplets is provided. In one embodiment, the apparatus includes a substrate having a set of electrical leads for connecting electrodes to a controller, a first set of electrodes, each connected to a separate one of the electrical leads, and a second set of electrodes, all connected to a single one of the electrical leads. In another embodiment, the apparatus includes a substrate having a set of X electrodes, and a set of Y electrical leads, each connected to one or more electrodes, wherein X is greater than Y. | 10-30-2008 |
20080296158 | DEVICE FOR ELECTROPHORESIS, DEVICE FOR TRANSFER, DEVICE FOR ELECTROPHORESIS AND TRANSFER, CHIP FOR ELECTROPHORESIS AND TRANSFER, AND METHOD FOR ELECTROPHORESIS, METHOD FOR TRANSFER, AND METHOD FOR ELECTROPHORESIS AND TRANSFER - A device for electrophoresis applies a voltage to a medium in contact with a plurality of electric conductors so that a potential of adjacent conductors is within a certain range. This allows preventing decline in electrophoresis speed. A device for electrophoresis and transfer includes an electrode having a plurality of electrode regions being insulated one another and arranged in a specific direction. This allows providing a practical and easy-to-use device for electrophoresis and transfer. A device for transfer alters an applied voltage or applied voltage duration to a certain position to another position. This allows improving transfer efficiency. | 12-04-2008 |
20080296159 | RADIATION-OR THERMALLY-CURABLE OXETANE BARRIER SEALANTS - This invention relates to cationically curable sealants that provide low moisture permeability and good adhesive strength after cure. The composition consists essentially of an electrophoretic device containing an oxetane compound and a photoinitiating system comprising and photoinitiator and optionally a photosensitizer. | 12-04-2008 |
20080302664 | Apparatus for driving fluid - An apparatus for driving a fluid includes a substrate, at least one electrode group and a controlling unit. The substrate has at least one plane. The electrode group is disposed on the substrate and includes a first electrode, a second electrode and a third electrode. A projecting position of the second electrode on the plane is disposed between that of the first electrode and that of the third electrode. The controlling unit electrically connected to electrode group is for driving the first to third electrodes. When the controlling unit drives the first to third electrodes to make the first and third electrodes have opposite polarities and to make the second and third electrodes have the same polarity, an electric field produced by the electrode group enables the fluid on the substrate to flow from the first electrode to the third electrode. | 12-11-2008 |
20090000949 | Method And Apparatus Of Concentration And Purification Of Nucleic Acid - In a method for concentration and purification method of nucleic acids using electrophoresis, cationic surfactant is added to a sample containing nucleic acids so as to adjust electric charge of impurities in the sample, and then the sample is placed in an electric field for electrophoresis so as to concentrate and purify the nucleic acids. The cationic surfactant ( | 01-01-2009 |
20090008255 | Arrangement for Generating Liquid Flows and/or Particle Flows, Method for Producing and Operating Said Arrangement and Use of the Latter - A device for producing at least one of fluid flows and particles flows includes a substrate having a substrate surface. The substrate surface includes a matrix including a plurality of regions having at least one of a different magnitude of a surface charge, a different sign of the surface charge, and a different height above the substrate. A fluid including at least partially electrically charged particles is disposed at the substrate surface. A first control element is configured to supply a plurality of electrical voltages to a plurality of electrode pairs. The electric field exerts a first force on a component of the fluid within an electrical double layer. The component is disposed adjacent to the substrate surface. The electric field exerts a second force within the double layer and outside the double layer, the second force is exerted on the at least partially electrically charged particles. | 01-08-2009 |
20090107843 | MICROCHIP PROCESSING METHOD AND APPARATUS - The processing apparatus for microchips, each at least having a main flow path performing migration of a sample for analysis inside a sheet-like member, comprises a holding part holding microchips so that the multiple main flow paths are provided; a pretreatment part common to the multiple main flow paths for performing a pretreatment step prior to an analysis step in each of the multiple main flow paths; a processing part for performing analysis in each of the main flow paths independently of the others; and a control part controlling an operation in the pretreatment part so that when a pretreatment step for one main flow path ends, a pretreatment for a next main flow path starts and further controlling an operation in the processing part so that an analysis is subsequently performed for the main flow path where the pretreatment step has ended. | 04-30-2009 |
20090114540 | Electro-Osmotic Dehydrator - Disclosed is an electro-osmotic dehydrator dehydrating sludges generated from the treatment plants of, such as, pure water, sewage water, night soil, waste water, etc. using three phase alternating current. | 05-07-2009 |
20090236226 | Modular microfluidic system and method for building a modular microfludic system - A “plug-n-play” modular microfluidic system is described herein which can be made by connecting multiple microfluidic components together to form a larger integrated system. For example, the modular microfluidic system includes a motherboard with interconnecting channels and integrated electrodes (or holes for electrodes to pass) which provide electronic connections to external data acquisition and system control devices. The modular microfluidic system can also include channel inserts (which are placed in the channels of the motherboard), heater units, actuator units, fitting components and microchips/modules with different functionalities which are placed on the motherboard. | 09-24-2009 |
20090301884 | Electrophoretic analysis system having in-situ calibration - An electrophoretic system having a plurality of separation lanes is provided with an automatic calibration feature in which each lane is separately calibrated. For each lane, the calibration coefficients map a spectrum of received channel intensities onto values reflective of the relative likelihood of each of a plurality of dyes being present. Individual peaks, reflective of the influence of a single dye, are isolated from among the various sets of detected light intensity spectra, and these can be used to both detect the number of dye components present, and also to establish exemplary vectors for the calibration coefficients which may then be clustered and further processed to arrive at a calibration matrix for the system. The system thus permits one to use different dye sets to tag DNA nucleotides in samples which migrate in separate lanes, and also allows for in-situ calibration with new, previously unused dye sets. | 12-10-2009 |
20090308750 | Electro-phoresis device - Provided is an electro-phoresis device that includes a light control layer, a first electrode, a second electrode and a third electrode. The light control layer may include a plurality of electro-phoresis particles. The first electrode and the second electrode may form an electric field to control of the electro-phoresis particles such that the electro-phoresis particles move towards at least one of the electrodes. The third electrode may be electrically connected to any one of the first and second electrodes and may have an electric polarity opposite to the other of the first and second electrode. | 12-17-2009 |
20090314643 | Electrophoresis Cassette and Method for Producing the Same - The object of the present invention is to inject smoothly a precursor to be a support and make an excellent support in which a boundary between a separation gel and a concentration gel after the injection is not ill-defined in the cassette which is made by combining two plates made of a synthetic resin, and in order to achieve the object, the present invention provides an electrophoresis cassette made by combining plates made of a synthetic resin which has a cavity for forming a support, wherein the surface of the plate which contacts with the support is covered with a SiOx film, and the SiOx film has a contact angle to water of 30° or less, and preferably 10° or less. | 12-24-2009 |
20090321262 | LIQUID TRANSFER DEVICE - Provided is a liquid transfer device which controls electrically liquid position. The surface of the liquid transfer device is provided with unevenness in order to solve a problem of having a large number of electrodes for controlling voltage. The number of electrodes for controlling voltage can be halved by utilization of restoring force of liquid to a spherical shape by surface tension, in addition to electrical force. | 12-31-2009 |
20100108518 | ELECTROPHORESIS CHIP AND ELECTROPHORESIS UNIT HAVING THE SAME - In order to provide a high-performance electrophoresis chip and an electrophoresis unit having the same that can restrain the diffusion of sample at an intersection between the electrophoresis groove and the sample introduction groove and prevent decrease in contrast and decrease in resolution, an electrophoresis chip is provided with a sample introduction groove, an electrophoresis groove, and a through hole. The sample introduction groove, the electrophoresis groove, and the through hole are formed on different substrates. In the electrophoresis chip, by combining the substrates, the sample introduction groove and the electrophoresis groove are located in different planes. | 05-06-2010 |
20100147691 | SYSTEMS AND METHODS FOR TRANSPORTING PARTICLES - Various particle transport systems and components for use in such systems are described. The systems utilize one or more traveling wave grids to selectively transport, distribute, separate, or mix different populations of particles. Numerous systems configured for use in two dimensional and three dimensional particle transport are described. | 06-17-2010 |
20100155247 | RADIATION-CURABLE RUBBER ADHESIVE/SEALANT - A radiation-curable adhesive/sealant composition comprises a radiation-curable rubber resin, one or more photoinitiators or photosensitizers, and optionally, one or more inorganic or organic fillers. | 06-24-2010 |
20100170798 | Fabrication and use of semipermeable membranes and gels for the control of electrolysis - A microfluidic device and method is disclosed having one or more membranes for the control of electrolysis. In one embodiment, a microfluidic device is disclosed that includes body with first channel and second channels separated by a gel layer. A first electrode positioned in the first channel and a second electrode positioned in the second channel wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the gel layer. In another embodiment, a microfluidic device includes a body having a surface with a channel separating two first reservoirs. One or more membranes are positioned on the surface covering a portion of the channel and a blank is positioned covering the channel and the one or more membranes. A second reservoir through the blank is in contact with the membrane, each second reservoir in communication with the channel via the membrane. A first electrode is positioned in the first reservoir and a second electrode is positioned in the second reservoir wherein a potential applied to the first and second electrodes passes electrons from the first channel to the second channel through the membranes. | 07-08-2010 |
20100175998 | Virtual channel platform - A virtual channel platform is disclosed. Said virtual channel platform comprises two electrode plates, which can provide an electric field, and two spacers set between said plates. Said plates are separated by said spacers for forming a passageway. A driven fluid is injected into said passageway. When applying electric signals of different frequencies in said plates, said plates form said electric field to drive said working fluid in a virtual channel. | 07-15-2010 |
20100175999 | MICROFLUIDIC DEVICE - The present invention relates to a microfluidic device, comprising a laminate of first and second films, one or each film including an integrally thermoformed structure such that the films together define an enclosed volume ( | 07-15-2010 |
20100200405 | Devices, systems and methods for separating magnetic particles - A method and device for separating from samples magnetic particles that contain capture compounds on their surfaces. The device includes a sheath including a magnet and including orienting pin adapted to concentrate or direct a magnetic field of the magnet; and a magnetizable plate with lid holes for receiving a vessel lid of a vessel, the magnetizable plate configured to receive the sheath and position the orienting pin over the vessel lid. In one method, magnetic beads with attached molecules are collected in the lids of the reaction vessel by the magnetic separator device provided herein and the separated magnetic particles, which carry the molecules of interest through affinity-based attachment chemistry and are held in the lid by the magnet of the device, are released into a new vessel containing a solution by removal of the separator device without the need for pipettes or liquid handling devices. | 08-12-2010 |
20100213067 | REACTION KIT TREATING EQUIPMENT - Upper space on the front surface side of a reaction plate, provided with at least a reaction container causing reaction in a sample and a reagent container containing a reagent used for reaction with the sample, is covered with an airtight cover. A dispensation tip ( | 08-26-2010 |
20100300883 | Microfluidic separation device - A microfluidic separation device is provided that includes a sample channel having a first sample channel region and a second sample channel region, where a cross-section of the first sample channel region is smaller than a cross-section of the second sample channel region. The invention further includes a detection region having a first detection region and a second detection region, where a cross-section of the first detection region is larger than a cross-section of the second detection region and the second sample channel region is connected to the first detection region. Additionally, the invention includes a marker input channel disposed to input markers into the second sample channel region, where the markers are larger than the cross-section of the first sample channel region and the cross-section of the second detection region, where the markers collect in the first detection region. | 12-02-2010 |
20100307921 | MICRODEVICE WITH INTEGRATED MEMORY - The present invention provides microdevices, such as those used in the pharmaceutical and biotechnological fields, including an integrated memory. According to various embodiments, the integrated memory is readable, writable, and rewritable. The present invention further provides processing stations, e.g., for carrying out electrophoresis, per, genetic analysis, sample preparation, and/or sample cleanup, etc., that are capable of reading from and/or writing/rewriting to such memory. | 12-09-2010 |
20110024297 | ELECTROOSMOTIC MOVABLE DEVICE - An electroosmotic movable device is provided, which includes a liquid chamber that houses a liquid, a conductive movable structure that is placed in the liquid chamber and has a rotating shaft or a supporting point and further has a conductive portion, and an electrode for applying an electric field to the conductive movable structure. The conductive movable structure is enabled to move by an electroosmotic flow which occurs in an electric double layer portion formed by being paired with an electric charge induced in the conductive movable structure owing to the electric field which is applied from the electrode. | 02-03-2011 |
20110048951 | DIGITAL MICROFLUIDICS BASED APPARATUS FOR HEAT-EXCHANGING CHEMICAL PROCESSES - The present invention provides an apparatus and method for performing heat-exchanging reactions on an electro wetting-based micro fluidic device. The apparatus provides one or multiple thermal contacts to an electro wetting-based device, where each thermal contact controls the part of the electro wetting-based device it communicates with to a designed temperature. The electrowetting-based device can be used to create, merge and mix liquids in the format of droplets and transport them to different temperature zones on the micro fluidic device. The apparatus and methods of the invention can be used for heat-exchanging chemical processes such as polymerase chain reaction (PCR) and other DNA reactions, such as ligase chain reactions, for DNA amplification and synthesis, and for real-time PCR. | 03-03-2011 |
20110048952 | MICROFLUIDIC INTERFACE - The invention allows for the formation of robust, reproducible, non-permanent connections to microchips. The connections are formed using either indexing arms or multiple fitting holder heads which are capable of forming a compression seal to a port located at any position on the surface of the microchip. The sealing force is user-defined and can be tightly controlled with integrated force sensors. In addition, the sealing force is monitored with a force sensor and force compensation mechanism ensuring that the desired force is maintained. The device is compatible with all microchip architectures. Alterations to the microchip surface is avoided as connections are established using instrumentation rather than processing steps. Further, the process is automatable allowing for exchanging microchips and subsequently creating electrical and fluidic connections in an automated fashion. Optionally, the integration of leak sensors to monitor leaks are included. | 03-03-2011 |
20110083963 | Liquid Transport Using Electrowetting Supported by Effective Arrangement of Electrodes - An arrangement of electrodes is provided in which there is a plurality of electrodes located in two planes and offset from one another in the direction of movement, and which within each plane are arranged in at least two electrically interconnected and alternating groups. A method is also provided for the movement or transport of drops of liquid utilizing the electrowetting effect and utilizing the above arrangement. | 04-14-2011 |
20110114492 | ELECTROKINETIC PUMP HAVING CAPACITIVE ELECTRODES - An electrokinetic pump achieves high and low flow rates without producing significant gaseous byproducts and without significant evolution of the pump fluid. A first feature of the pump is that the electrodes in the pump are capacitive with a capacitance of at least 10 | 05-19-2011 |
20110168562 | Nanopore and Carbon Nanotube Based DNA Sequencer - The present invention provides a device for analyzing the composition of a heteropolymer comprising a carbon nanotube through which the heteropolymer is driven by electrophoresis. The carbon nanotube also serves as one electrode in a reading circuit. One end of the carbon nanotube is held in close proximity to a second electrode, and each end of the carbon nanotube is functionalized with flexibly-tethered chemical-recognition moieties, such that one will bind one site on the emerging polymer, and the second will bind another site in close proximity, generating an electrical signal between the two electrodes when the circuit is completed by the process of chemical recognition. | 07-14-2011 |
20110186435 | LIQUID MIXING APPARATUS - A liquid mixing apparatus includes a flow channel configured to supply a liquid therethrough; a vortex-flow generating unit including a conductive member and an electrode, and configured to generate a vortex flow in the liquid in the flow channel by an electric field, the conductive member being provided in the flow channel, the electrode applying the electric field to the conductive member; a directional-flow generating unit connected to an end portion of the flow channel and configured to generate a flow of the liquid in a direction along the flow channel; and a switching unit configured to switch between the vortex flow and the directional flow. | 08-04-2011 |
20110186436 | Particle Interrogation Devices and Methods - Devices, apparatus and methods are disclosed for non-contact pneumatic sampling and sampling of surfaces, persons, articles of clothing, buildings, furnishings, vehicles, baggage, packages, mail, and the like, for contaminating aerosols indicative of a hazard or a benefit, where the contaminating aerosols are chemical, radiological, biological, toxic, or infectious in character. In a first device, a central orifice for pulling a suction gas stream is surrounded by a peripheral array of convergingly-directed gas jets, forming a virtual sampling chamber. The gas jets are configured to deliver millisecond pneumatic pulses that erode particles from solid surfaces at a distance. In another aspect of the invention, a suction gas stream is split using an air-to-air concentrator so that a particle-enriched gas flow is directed to a particle trap and any particles immobilized in the particle trap (including any adsorbed vapors associated with the particles) are selectively analyzed to detect trace residues associated with explosives. | 08-04-2011 |
20110203931 | Particle Interrogation Devices and Methods - Devices, apparatus and methods are disclosed for non-contact pneumatic sampling and sampling of surfaces, persons, articles of clothing, buildings, furnishings, vehicles, baggage, packages, mail, and the like, for contaminating aerosols or vapors indicative of a hazard or a benefit, where the contaminating aerosols or vapors are chemical, radiological, biological, toxic, or infectious in character. In a first device, a central orifice for pulling a suction gas stream is surrounded by a peripheral array of convergingly-directed gas jets, forming a virtual sampling chamber. The gas jets are configured to deliver millisecond pneumatic pulses that erode particles and vapors from solid surfaces at a distance. In another aspect of the invention, a suction gas stream is split using an air-to-air concentrator so that a particle-enriched gas flow is directed to a particle trap and particles immobilized therein are selectively analyzed for explosives and explosives related materials under optimized conditions for analyzing particle-associated constituents and a bulk flow is directed to a vapor trap and free vapors immobilized therein are selectively analyzed for explosives and explosives related materials under optimized conditions for analyzing free vapors. Detection signals from the particle channel and the vapor channel are compared or integrated to detect trace residues associated with explosives. | 08-25-2011 |
20110259749 | Flow cytometer and flow cytometry - One embodiment of the present invention is to provide a system for sorting cell particles in a liquid flow, which comprises a flow-defining block including a flow chamber receiving a sample conduit and a flow cell having a flow channel. The system also comprises a strobe block including a imaging device for taking an image of a jet flow ejected from the flow-defining block and a plurality of droplets in a given image area. The flow-defining block and the strobe block are detachably connected each other. Further the strobe block includes a nozzle plate having a nozzle channel between a receiving end and a nozzle. The flow-defining block includes a discharge end opposite to the receiving end and a channel enlarged portion of which cross section taken along a predetermined plane perpendicular to a flow direction has an area increasing towards the discharge end. The discharge end and the receiving end have substantially the same open distance in the predetermined plane perpendicular to the flow direction. | 10-27-2011 |
20120006684 | ARRAY ELEMENT CIRCUIT AND ACTIVE MATRIX DEVICE - An array element circuit with an integrated impedance sensor is provided. The array element circuit includes an array element which is controlled by application of a drive voltage by a drive element; writing circuitry for writing the drive voltage to the drive element; and sense circuitry for sensing an impedance presented at the drive element. | 01-12-2012 |
20120031761 | ANALYSIS APPARATUS - An analysis apparatus enables a plurality of analysis processes to be accurately and efficiently performed. The analysis apparatus includes a detention tank in which a specimen is stored, and a voltage applier. The voltage applier includes a power source and a contact tip to be brought into contact with the specimen for applying a voltage necessary for analyzing the specimen. The voltage applier renews the contact tip from a used state to an unused state after completing an analysis and before starting the subsequent analysis. | 02-09-2012 |
20120055798 | Unitary Biochip Providing Sample-in to Results-out Processing and Methods of Manufacture - A biochip for the integration of all steps in a complex process from the insertion of a sample to the generation of a result, performed without operator intervention includes microfluidic and macrofluidic features that are acted on by instrument subsystems in a series of scripted processing steps. Methods for fabricating these complex biochips of high feature density by injection molding are also provided. | 03-08-2012 |
20120067725 | Apparatuses and Methods for Control and Self-Assembly of Particles into Adaptable Monolayers - Apparatuses and methods for the control and self-assembly of particles into adaptable monolayers and changing the relative position of a plurality of particles at an interface between two fluids, including applying an electric field perpendicular to the interface; moving the particles vertically in the interface in response to applying the electric field; moving the particles laterally within the interface in response to the electric field and capillary forces; maintaining the particles at the interface when moving the particles vertically; and maintaining the particles at the interface when moving the particles laterally. | 03-22-2012 |
20120085651 | METHOD OF PREPARING NEUTROPHIL-DEPLETED PLATELET-RICH PLASMA - Methods of producing neutrophil-depleted platelet-rich plasma by passing a blood, platelet or platelet-rich plasma fraction through a narrow, twisted and/or charged environment to remove neutrophils and produce neutrophil-depleted platelet-rich plasma is described. The neutrophil-depleted platelet-rich plasma may be depleted in neutrophils by 75% or more and includes at least 0.5×10 | 04-12-2012 |
20120181178 | FLUIDIC DEVICE FOR ELECTROPHORESIS OF MOLECULES - A fluidic device is disclosed for making electrophoresis of molecules. The device has channels of closed geometry and variable powers over time. Migration of molecules is contained within channel of closed geometry, whereby they can circulate again and again, thus separating the molecules at a wide migration distance. The device has an injection system which is a secondary channel which intersects the main channel. An arrangement of electrodes along this main channel connected to a variable voltage source with multiple outlets which regulates the value of the electric power in each electrode, and the frequency at which the same varies from one electrode to another. Thus it is achieved to generate a periodic arrangement of powers along the channel which set the flow of the sample optimizing the separation process. Electrodes can be added for the detection of molecules by measuring the changes in electric resistivity, current or voltage. | 07-19-2012 |
20120234680 | PARTICLE TRANSPORTER - A particle transporter based on travelling-wave dielectrophoresis is provided. The particle transporter includes a plurality of turn-around electrodes. The turn-around electrodes are disposed on a substrate and arranged in a fan shape. The turn-around electrodes provide an arc channel for transporting a plurality of particles. Wherein, the turn-around electrodes are not connected to each other, and neighboring sides of any two adjacent electrodes of the turn-around electrodes are approximately parallel. | 09-20-2012 |
20120312689 | PUMP - A pump includes a flow passage through which a liquid containing an electrolytic solution is conveyed, a pair of electrodes in the flow passage to apply an electric field along the direction in which the liquid is conveyed, and a conductive member connected to one of the pair of electrodes and in contact with the liquid in the flow passage. The conductive member includes a sidewall portion that locally divides a flow of the liquid in the flow passage. The conductive member connected to one of the pair of electrodes may be a polyhedron or a column that is convex toward the electrode to which the conductive member is not connected. | 12-13-2012 |
20130020202 | Cartridge and System for Manipulating Samples in Liquid Droplets - A cartridge ( | 01-24-2013 |
20130026040 | Digital Microfluidic Platform for Actuating and Heating Individual Liquid Droplets - A digital microfluidic platform utilizes dual active matrix circuitry to actuate and heat liquid droplets on a biochip. Liquid droplets are introduced into a droplet handling area of the biochip where they can be actuated by electrodes residing in pixels of an actuating active matrix array according to the electrowetting on dielectric phenomenon and heated by heating elements residing in pixels of a heating active matrix array. Pixels of the actuating active matrix array and the heating active matrix array are independently addressable such that droplets in the droplet handling area can be selectively heated and actuated according to their location. The actuating active matrix array and heating active matrix array can be formed on the same or different substrates with the droplet handling area disposed above or between the substrates. | 01-31-2013 |
20130068622 | Method and apparatus for real-time monitoring of droplet composition in microfluidic devices - A device for real time monitoring of fluid composition in microfluidic devices. The invention can be integrated into any microfluidic device where fluid moves along a pathway with a measurement region consisting of at least two measurement electrodes. The fluidic pathway can contain an unbound droplet, a droplet confined in at least one aspect, or a continuous flow. The device also includes control circuitry connected to measurement electrodes that allows for the determination of the droplet composition by measuring at least one of capacitance, resistance, or impedance between said electrodes. This invention can (1) measure droplet composition, (2) compare composition against a known sample, (3) monitor droplet mixing, (4) control mixing to achieve specific mixing ratios, (5) measure the particle concentration within a droplet, (6) determine the position of particles in a droplet, and (7) monitor chemical reactions. These functions call all be performed in real time. | 03-21-2013 |
20130126358 | SYSTEM FOR MANIPULATING SAMPLES IN LIQUID DROPLETS - A liquid droplet manipulation system has a substrate with at least one electrode array and a central control unit for controlling selection of individual electrodes of the electrode array and for providing the electrodes with individual voltage pulses for manipulating liquid droplets by electrowetting. A working film is placed on top of the electrodes for manipulating samples in liquid droplets with the electrode array. At least one selected individual electrode of the electrode array is configured to be penetrated by light of an optical detection system for the optical inspection or analysis of samples in liquid droplets that are located on the working film. Also disclosed is working film that is to be placed on the electrode array and a cartridge that includes such a working film for manipulating samples in liquid droplets. | 05-23-2013 |
20140069813 | SYSTEM AND METHODS FOR MOVING OBJECTS INDIVIDUALLY AND IN PARALLEL - Electro-osmosis is used to create droplets in order to easily, carefully, and quickly pick-and-place millions of objects (ranging in size from millimeters to nanometers) individually or in parallel. Droplets are formed within channels that are individually controlled in order to achieve a predetermined configuration of the selected objects. | 03-13-2014 |
20140102903 | APPARATUS FOR PARTICLE REMOVAL - Methods and apparatus for cleaning a substrate (e.g., wafer) in the fabrication of semiconductor devices utilizing electrorheological (ER) and magnetorheological (MR) fluids to remove contaminant residual particles from a surface of the substrate are provided. | 04-17-2014 |
20140174932 | MICROORGANISM QUANTITY MEASUREMENT CELL AND MICROORGANISM QUANTITY MEASUREMENT DEVICE COMPRISING SAME - A measurement cell comprises a measurement chamber; an inflow aperture through which a sample liquid flows into the measurement chamber; an outflow aperture through which the sample liquid flows out of the measurement chamber; a measurement electrode which is provided in the measurement chamber at a position toward the outflow aperture, traps microorganisms contained in the sample liquid that flows in the measurement chamber, and to which a measurement AC voltage is applied for measuring the quantity of the microorganisms; a concentration electrode which is provided in the measurement chamber at a position toward the inflow aperture, and to which a concentration-use AC voltage is applied for imparting a repulsive force that guides the microorganisms contained in the sample liquid to the measurement electrode side; and insulators which are provided on the concentration electrode, and on which is formed an electrical field convergence unit that produces a repulsive force in a portion of the insulators when the concentration-use AC voltage is applied to the concentration electrode. | 06-26-2014 |
20140190831 | ACTUATION OF VALVES USING ELECTROOSMOTIC PUMP - A method of actuating a valve, comprises operatively coupling the valve with an electroosmotic pump; flowing a fluid through the electroosmotic pump; and generating a fluidic pressure of at least 0.75 PSI to actuate the valve, wherein the electroosmotic pump comprises one or more thin, porous, positive electroosmotic membranes and one or more thin porous, negative electroosmotic membranes; a plurality of electrodes comprising cathodes and anodes, and a power source; wherein each of the positive and negative electroosmotic membranes are disposed alternatively and wherein at least one of the cathodes is disposed on one side of one of the membranes and at least one of the anodes is disposed on the other side of the membrane and wherein at least one of the cathodes or anodes is disposed between a positive and a negative electroosmotic membrane. | 07-10-2014 |
20140202865 | ELECTROOSMOTIC MOVABLE DEVICE - An electroosmotic movable device is provided, which includes a liquid chamber that houses a liquid, a conductive movable structure that is placed in the liquid chamber and has a rotating shaft or a supporting point and further has a conductive portion, and an electrode for applying an electric field to the conductive movable structure. The conductive movable structure is enabled to move by an electroosmotic flow which occurs in an electric double layer portion formed by being paired with an electric charge induced in the conductive movable structure owing to the electric field which is applied from the electrode. | 07-24-2014 |
20140216938 | MICRO-CHEMICAL MIXING - A device comprising, a substrate having a droplet thereover, and an electrical source coupleable to the substrate. The electrical source is configured to apply a voltage between the substrate and the droplet using an electrode. The electrode has a first portion and a second portion non-symmetric to the first portion, the first and second portions defined by a plane located normal to a longitudinal axis and through a midpoint of a length of the electrode. | 08-07-2014 |
20140231257 | DROPLET ACTUATOR APPARATUS AND SYSTEM - Droplet actuator apparatus and system are provided. An apparatus comprises: a microfluidics system having an insertion slot for insertion of a droplet actuator; a bottom plate against which the droplet actuator would slide when inserting the droplet actuator into the insertion slot; and means for forcing a substrate in the droplet actuator parallel to the bottom plate, wherein warpage in the substrate is corrected. | 08-21-2014 |
20140231258 | ELECTROKINETIC PUMP HAVING CAPACITIVE ELECTRODES - An electrokinetic pump achieves high and low flow rates without producing significant gaseous byproducts and without significant evolution of the pump fluid. A first feature of the pump is that the electrodes in the pump are capacitive with a capacitance of at least 10 | 08-21-2014 |
20140246320 | Method and Apparatus for the Characterizing and Counting Particles, in Particular, Biological Particles - The present invention relates to a method and an apparatus for the characterization and/or the counting of particles by means of non uniform, time variable force fields and integrated optical or impedance meter sensors. The force fields can be of positive or negative dielectrophoresis, electrophoresis or electro-hydrodynamic motions, characterized by a set of stable equilibrium points for the particles (solid, liquid or gaseous); the same method is suitable for the manipulation of droplets (liquid particles) by exploiting effects known to the international scientific community with the name of Electro-wetting on dielectric. The aim of the present invention is to act on the control of the position of each particle which is present in the sample, for the purpose of displacing such particles in a deterministic or statistical way, in order to detect their presence with the integrated optical or impedance meter sensors and/or characterize their type, for the purpose of counting or manipulating them in an efficient way. | 09-04-2014 |
20140251811 | Electrowetting Dispensing Devices and Related Methods - A device having a first substrate and a second substrate separated from the first substrate to form a volume between the first and second substrates, electrodes disposed on the first and second substrates and facing the volume, each substrate comprising at least one electrode, and a first insulating layer disposed on the first substrate and a second insulating layer disposed on the second substrate to separate the electrodes from the volume. | 09-11-2014 |
20140374259 | Electrowetting Dispensing Devices and Related Methods - A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting. | 12-25-2014 |
20150008129 | Electrowetting Dispensing Devices and Related Methods - A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting. | 01-08-2015 |
20150014170 | MICROSTRUCTURED POLYMER DEVICES - A method of manufacturing a device with a planar electrode structure, the method comprising: (a) forming a microfluidic channel on a substrate; (b) applying a primer layer to at least part of the microfluidic channel, (c) applying a conductive liquid to the microfluidic channel, the conductive liquid comprising electrically conductive particles dispersed in a carrier medium, the carrier medium including a solvent; (d) allowing the conductive liquid to flow throughout the microfluidic channel by capillary action to form the planar electrode structure; and (e) evaporating the solvent from the carrier medium, is described. Devices obtainable using the method and their applications are also described. | 01-15-2015 |
20150021186 | Devices for Flow Step Focusing (FSF) - Flow step focusing isolates and concentrates a molecule of interest by flowing a liquid comprising a molecule of interest through a main channel having an inlet and an outlet with application of a first pressure at the inlet; applying a voltage along the channel during the flowing, wherein the voltage is configured to have a polarity such that it drives the molecule of interest in a direction opposite the flow of the liquid; controlling the first pressure and/or the voltage in a manner so as to trap and concentrate the molecule of interest in a region of the main channel; and removing the concentrated molecule of interest from the channel by recovering a portion of the liquid from a side channel diverging from the main channel, wherein the side channel is maintained at a pressure lower than the first pressure. Also disclosed is an apparatus for such. | 01-22-2015 |
20150034486 | POLARIZABLE CONNECTION STRUCTURE AND DEVICE INCLUDING THE SAME - Provided is a device capable of functionalizing a micro-motion of a polarizable microstructure. A structure includes a plurality of polarizable structures, each having an electrically polarizable conductive part on a surface thereof, and a connector body having one of mobility and deformability, for connecting the plurality of polarizable structures to each other. | 02-05-2015 |
20150075991 | Techniques and Droplet Actuator Designs for Reducing Bubble Formation - During droplet operations in a droplet actuator, bubbles often form in the filler fluid in the droplet operations gap and interrupt droplet operations. The present invention provides methods and systems for performing droplet operations on a droplet in a droplet actuator comprising maintaining substantially consistent contact between the droplet and an electrical ground while conducting multiple droplet operations on the droplet in the droplet operations gap and/or reducing the accumulation of electrical charges in the droplet operations gap during multiple droplet operations. The methods and systems reduce or eliminate bubble formation in the filler fluid of the droplet operations gap, thereby permitting completion of multiple droplet operations without interruption by bubble formation in the filler fluid in the droplet operations gap. | 03-19-2015 |
20150338372 | Electrowetting Dispensing Devices and Related Methods - A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting. | 11-26-2015 |
20150338373 | Electrowetting Dispensing Devices and Related Methods - A method for dispensing liquid for use in biological analysis may comprise positioning liquid to be dispensed via electrowetting. The positioning may comprise aligning the liquid with a plurality of predetermined locations. The method may further comprise dispensing the aligned liquid from the plurality of predetermined locations through a plurality of openings respectively aligned with the predetermined locations. The dispensing may be via electrowetting. | 11-26-2015 |
20160011148 | Apparatus and Method for Evaluating Characteristics of Target Molecules | 01-14-2016 |
20160031730 | SYSTEMS AND METHODS FOR ION SEPARATION IN AN AQUEOUS SOLUTION - Systems and methods for providing a deionization chamber having a plurality of electrodes corresponding to a plurality of register levels thereby forming a gradient of electrical amplitudes and frequencies within the deionization chamber. | 02-04-2016 |
20160116437 | MULTI-CHANNEL FLOW DIRECTION CONTROLLER FOR FREE-FLOW ELECTROPHORESIS APPARATUS - A multi-channel flow direction controller for a free-flow electrophoresis apparatus, including a base and a propulsion member. The base is provided with a plurality of convex pieces. The propulsion member is provided with a plurality of narrow pieces. The convex pieces and the narrow pieces have the same length and number. One end of the base is provided with a groove, and one end of the propulsion member is disposed in the groove. | 04-28-2016 |
20160129437 | INSTRUMENT AND CARTRIDGE FOR PERFORMING ASSAYS IN A CLOSED SAMPLE PREPARATION AND REACTION SYSTEM EMPLOYING ELECTROWETTING FLUID MANIPULATION - In one embodiment, a multiplex fluid processing cartridge includes a sample well, a deformable fluid chamber, a mixing well with a mixer disposed therein, a lysis chamber including a lysis mixer, an electrowetting grid for microdroplet manipulation, and electrosensor arrays configured to detect analytes of interest. An instrument for processing the cartridge is configured to receive the cartridge and to selectively apply thermal energy, magnetic force, and electrical connections to one or more discrete locations on the cartridge and is further configured to compress the deformable chamber(s) in a specified sequence. | 05-12-2016 |
20160185628 | APPARATUS FOR PURIFYING A FLUID AND METHOD FOR THE ATTAINMENT THEREOF - Apparatus for purifying a fluid, which comprises electrode layers facing each other, power supplied to different polarities with spacer layers interposed, and traversed by a flow of fluid to be treated containing ionized particles. The electrode layers and the spacer layers are wound as a spiral around a longitudinal extension axis inside the suitably cylindrical containment structure. The power supply comprises a pair of collectors that are extended with portions inside the winding connected to the corresponding first internal sides of the electrode layers at the longitudinal extension axis. | 06-30-2016 |