Zarate
Alfredo R. Zarate, Bethesda, MD US
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20110295176 | VENOUS DEVICE - A needle can include a fluid directing portion comprising a U-shaped lateral orifice extending between the exterior and interior surfaces and a corresponding U-shaped diverter adjacent to the U-shaped lateral orifice. A diverter can be disposed within a lumen of a needle and transverse to a central axis within the lumen. | 12-01-2011 |
20120059354 | METHODS OF IMPROVING FLUID DELIVERY - A method of reducing cell damage can include inserting device into a blood vessel, wherein the device includes a hollow shaft, a lumen, a fluid directing portion comprising a U-shaped lateral orifice extending between the exterior and interior surfaces and a corresponding U-shaped diverter adjacent to the U-shaped lateral orifice, wherein the diverter is disposed within the lumen and transverse to the central axis, and decreasing free plasma hemoglobin levels, thereby reducing damage to circulating blood cells or endothelium during dialysis. | 03-08-2012 |
20120065567 | HEMODIALYSIS SYSTEM AND METHOD - Hemodialysis systems and methods with streamlined blood flow paths are provided. Such streamlined blood flow paths facilitate flow without undue damage to circulating cells. | 03-15-2012 |
Boris A. Zarate, Columbia, SC US
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20120209538 | Determination of the Remaining Life of a Structural System Based on Acoustic Emission Signals - In accordance with the present disclosure, a method of using acoustic emission data to predict the state of a structural element is described. The method includes capturing acoustic emission data for a structural element. The method further includes predicting the future stress intensity in the structural element using the captured acoustic emission data and calculating the probability of future failure of the structural element using the predicted future stress intensity. | 08-16-2012 |
Carlos Zarate, Hamilton CA
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20090074283 | SYSTEM AND METHODS FOR RAPID AND AUTOMATED SCREENING OF CELLS - A system for performing automated cell screening in drug discovery, includes an automated microscope, a fast autofocus device, and a digital imaging system. Processes are implemented in software through which relevant cellular material is segmented and quantified with minimal user interaction. Improvements in the following areas: known methods for image processing are implemented in such a way that automated segmentation is achieved; sets of known measurements (pixel counting, etc.) are implemented as methods which demonstrate aspects of biology in a reliable fashion; components for automated positioning, focusing, imaging and processing of a multiplicity of samples are integrated as systems within which the segmentation and measurement methods may be mounted; and components and methods are adapted into systems which yield more highly automated and more rapid cell screening. | 03-19-2009 |
Carlos Zarate, Caba AR
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20100254590 | SYSTEM AND METHODS FOR RAPID AND AUTOMATED SCREENING OF CELLS - A system for performing automated cell screening in drug discovery, includes an automated microscope, a fast autofocus device, and a digital imaging system. Processes are implemented in software through which relevant cellular material is segmented and quantified with minimal user interaction. Improvements in the following areas: known to methods for image processing are implemented in such a way that automated segmentation is achieved; sets of known measurements (pixel counting, etc.) are implemented as methods which demonstrate aspects of biology in a reliable fashion; components for automated positioning, focusing, imaging and processing of a multiplicity of samples are integrated as systems within which the segmentation and measurement methods may be mounted; and components and methods are adapted into systems which yield more highly automated and more rapid cell screening. | 10-07-2010 |
20130129212 | METHOD FOR REDUCING IMAGE ARTIFACTS PRODUCED BY A CMOS CAMERA - The present invention relates to a system and method for reducing image artifacts for a CMOS camera used as an optical detector for a line confocal fluorescent imager. The method for reducing image artifacts in a monochromatic image comprises subtracting RGB channel offset mismatch; and correcting random row offset for each row. Preferably, the method also comprises correcting random column offset and gain. Optionally, the method also comprises clipping of defective pixels, and/or subtracting dark current. When the monochromatic image is a fluorescence image, the method also comprises a step of compressing CMOS camera noise. Also provided are a system for reducing image artifacts in a monochromatic image from a CMOS camera, as well as an image artifact reduction system for a CMOS camera-based line confocal fluorescent microscope. | 05-23-2013 |
Carlos A. Zarate, Rockville, MD US
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20140256821 | INTRANNASAL ADMINISTRATION OF KETAMINE TO TREAT DEPRESSION - Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>2 years). | 09-11-2014 |
20150056308 | INTRANASAL ADMINISTRATION OF KETAMINE TO TREAT DEPRESSION - Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>2 years). | 02-26-2015 |
Carlos A. Zarate, Germantown, MD US
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20140296241 | THE USE OF (2R, 6R)-HYDROXYNORKETAMINE, (S)-DEHYDRONORKETAMINE AND OTHER STEREOISOMERIC DEHYDRO AND HYDROXYLATED METABOLITES OF (R,S)- KETAMINE IN THE TREATMENT OF DEPRESSION AND NEUROPATHIC PAIN - The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or hydroxylated ketamine metabolite. (2R,6R)-hydroxynorketamine The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain disorder (CRPS) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment. | 10-02-2014 |
Cartos Zarate, Puerto Ordaz VE
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20090212571 | WAVE POWER SYSTEM FOR EXTRACTING SIMULTANEOUSLY BOTH POTENTIAL AND KINETIC ENERGY AT VARIABLE SIGNIFICANT WAVE HEIGHTS AND PERIODS - A wave energy conversion system or device includes a float and base on top of which there is a power take-off system. The float, its base and the machine room are inserted in a main column supported by legs and corresponding leg supports on the bottom floor in shallow waters (seas or lakes). In deeper waters, the main column may be supported by column supports attached to an underwater float. The machine room is separated of the float frame through a rotary joint which allows the float and base to rotate in any horizontal direction while maintaining the machine room fixed in the same horizontal direction. The rotary joint separating the float frame and the machine room also allows for the vertical up and down movement when interacting with incoming waves. The distance between the machine room and the float frame is always the same. The device includes flaps or blades for the absorption of kinetic energy derived from the back and forth movement of water generated by waves. The device extracts potential energy of the wave from the up and down movement of the floating structure through a power take-off system in the machine room. | 08-27-2009 |
Eugene Anthony Zarate, Powell, OH US
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20140088884 | METHODS OF SOURCE ATTRIBUTION FOR CHEMICAL COMPOUNDS - Methods of determining the source of an unknown sample are disclosed. Mass spectra from possible sources are obtained using two-dimensional gas chromatography coupled with time-of-flight mass spectrometry. That data is processed to obtain a dataset. A random forest algorithm is used to classify the dataset and create a classifier that distinguishes between the possible sources. | 03-27-2014 |
Gabriel Aurelio Zarate, Plazas Verdes CO
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20090133456 | PROCESS AND MECHANISM TO PRODUCE GRANULATED ORGANIC-MINERAL FERTILIZER BASED ON CONCENTRATED VINASSE - A process and mechanism to produce granulated organic-mineral fertilizer based on concentrated vinasse, comprising specific conditions of raw material preparation, volume and amounts of mixtures, humidity of the materials used in the mixture, homogenization, granulation, drying and packaging, relation on amount of the product intended to granulate versus length of the granulator cylinder, temperature of the gases for draying, speed of the gas for draying and relation on the length versus diameter of the dryer. To improve the fertilizer composition and its mixing with conventional fertilizers, the present invention uses other sub-products from the sugar cane mill and alcohol distillery industries to obtain organic-mineral fertilizers that replace conventional fertilizers, providing organic materials and microorganisms, required for the reactivation of the soil fertility and a superior approach by the plants, resulting in an increasing of the harvesting productivity and the use of smaller amounts compared with conventional fertilizers. | 05-28-2009 |
Gustavo Azgad Zarate, Redlands, CA US
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20160073791 | WOMB EXPERIENCE COLIC CONTROLLING INFANT CARRIER - The invention consists of an infant carrier/harness that incorporates sound speakers on the interior portion of the carrier, where the baby places his or her back; additionally, there is a “halo” speaker that is incorporated into a Head Cover of the carrier which completes the overall sound experience; it also serves to block out light. The speakers connect to a sound/white noise apparatus—or can connect to a mobile phone, or other portable device to produce sound, creating an ambient and constant “shush” sound. The object of the sound and cover is to re-create a womb-like experience. The infant carrier harness will also have the ability to plug in a mobile device to play other sounds and or music. | 03-17-2016 |
Jaime Zarate, Puerto Ordaz VE
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20090212571 | WAVE POWER SYSTEM FOR EXTRACTING SIMULTANEOUSLY BOTH POTENTIAL AND KINETIC ENERGY AT VARIABLE SIGNIFICANT WAVE HEIGHTS AND PERIODS - A wave energy conversion system or device includes a float and base on top of which there is a power take-off system. The float, its base and the machine room are inserted in a main column supported by legs and corresponding leg supports on the bottom floor in shallow waters (seas or lakes). In deeper waters, the main column may be supported by column supports attached to an underwater float. The machine room is separated of the float frame through a rotary joint which allows the float and base to rotate in any horizontal direction while maintaining the machine room fixed in the same horizontal direction. The rotary joint separating the float frame and the machine room also allows for the vertical up and down movement when interacting with incoming waves. The distance between the machine room and the float frame is always the same. The device includes flaps or blades for the absorption of kinetic energy derived from the back and forth movement of water generated by waves. The device extracts potential energy of the wave from the up and down movement of the floating structure through a power take-off system in the machine room. | 08-27-2009 |
Jessica Lynn Zarate, Redford, MI US
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20100040765 | Lifting and Preserving Bloody Impressions for Law Enforcement - A lifting strip containing titanium dioxide has been successful in the lifting and enhancement of bloody impressions from nonporous, semi porous and porous surfaces. The lifting strip is best when activated with an alcohol such as ethanol or methanol. When the lifting strip has dried after application it can easily be removed from the surface lifting the bloody impression onto a contrasting white background for examination. This method is safe, easy, and effective on several surfaces of contrasting colors. | 02-18-2010 |
20100136208 | Lifting and Preserving Bloody Impressions for Law Enforcement - A fluorogenic lifting strip containing titanium dioxide has been successful in the lifting and enhancement of impressions and bloody impressions from nonporous, semi porous and porous surfaces. The lifting strip is best when activated with an alcohol such as ethanol or methanol. When the lifting strip has dried after application it can easily be removed from the surface lifting the impression onto a contrasting white background. The lifting trip can be subsequently visualized with an ALS or Laser to fluoresce the lifted impression with optimal contrast for visualization and examination. This method is safe, easy, and effective on several surfaces of contrasting colors. | 06-03-2010 |
Victor Manuel Perez Zarate, Halfmoon, NY US
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20110306864 | POSITIONER FOR ULTRA-PORTABLE IMAGING SYSTEM - A flexible, lightweight, easily maneuverable positioner for an imaging system. The positioning system in one example has a cart section with a base frame coupled to one or more wheels. There is a mast extending from the cart section and a linkage assembly coupled to a second end of the mast, wherein the mast is configured to swing about a vertical plane. There is a positioning arm coupled to the linkage assembly, wherein the positioning arm is configured to swing about at least one of a horizontal plane and the vertical plane. An imaging bracket is used to couple to the positioning arm and configured to receive an imaging unit. In one example, the positioner is coupled together by fasteners, wherein the positioner can be assembled and dis-assembled via the fasteners without tools | 12-15-2011 |
20140324908 | METHOD AND SYSTEM FOR INCREASING ACCURACY AND COMPLETENESS OF ACQUIRED DATA - The present disclosure relates to the use of both semantic analysis and statistical text mining to process data records, improving the completeness and accuracy of records so processed. By way of example, a data record may be iteratively processed by text mining using seeds derived from a semantic template and by validating the results based on semantic reasoning based on the semantic template. | 10-30-2014 |
Walter Zarate, Prospect Place, NJ US
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20120096782 | Hidden Ridge Vent for Slate Roofs - A ridge ventilation system includes a plurality of ridge vent sections configured to be arranged end-to-end along the ridge of a roof covering a vent slot formed therealong. Each ridge vent section has an elongated longitudinally flexible top panel with a central portion, edge portions terminating at extreme edges of the top panel, and ventilation grids extending beneath and along the edge portions spaced from extreme edges thereof. The space between the extreme edges of the top panel and the ventilation grids forms or defines an overhang configured to receive edges of shingles in a course of shingles installed next to the vent section and to inhibit the edges of the shingles from rising up. The ridge vent sections also have depending deflectors for deflecting blowing rain and snow that might enter through the ventilation grids and filter fabric may be affixed to the bottom of the ridge vent sections to provide additional deflection of rain and snow. The ridge ventilation system is particularly useful with slate or slate-style roofs and the vent sections are sized so that ridge cap slates extend beyond the extreme edges of the sections to hide substantially the ridge ventilation system from view. | 04-26-2012 |
20130165038 | Mesh Vent with Varying Density or Integral Moisture Barrier - A mesh ridge vent has an air permeable layer formed of randomly aligned synthetic fibers that are opened and blended, randomly aligned into a web by airflow, joined by phenolic or latex binding agents, and heat cured to produce an air-permeable varying mesh. A moisture barrier may be integrally formed above the air permeable layer and may be defined by a coating or by a layer of fibers that is sufficiently dense to inhibit penetration of water into the web. The mesh ridge vent has edge portions and a central portion and the edge portions may be more dense and thicker while the central portion may be less dense and thinner than the edge portions. | 06-27-2013 |
Walter Zarate, Wayne, NJ US
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20140259998 | Multi-Purpose Ridge Vent System - A solar ridge vent includes an elongated laterally flexible panel having edge portions and ventilation grids extending along the edge portions. Channel members extend along the edge portions of the panel and define channels that have channel openings facing inwardly. The channels are sized to receive edges of auxiliary components to hold the auxiliary components on the ridge vent. The auxiliary components may be ridge cap shingles, slate cap shingles, light emitting emergency location panels, or fluid heating panels. In a preferred embodiment, solar power generating panels are configured to be mounted on the ridge vent with its edges held in the channels. A remote electrical box has chargeable batteries, a power inverter, and an AC outlet to provide electrical power in an emergency. | 09-18-2014 |
20140259999 | Low Profile Slate-Style Solar Roofing System - A solar roofing panel has a rectangular body with solar cells exposed on the upper surface of the body and an electrical junction box on the lower surface of body along the forward edge portion thereof. A cutout is formed in the upper edge portion of the rectangular body at a corner thereof. When a plurality of solar panels are arranged on a roof in courses with an upper course partially overlapping a lower course, the junction boxes of roofing panels in the upper course are disposed in the cutouts of roofing panels of the lower course. Accordingly, the solar roofing panels present a low profile mimicking the profile of slate-style shingles. | 09-18-2014 |
Walter Zarate, Prospect Park, NJ US
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20100043312 | Fascia Vent - A fascia vent for a roof structure includes a fascia board for attachment along the lower ends of roof rafters that support a roof deck above an attic space. The fascia vent has an exposed outside face and an inside face at least partly exposed to the attic space. In one embodiment, a plurality of slots are formed along the inside face of the fascia board with a lower end of the slots communicating with ambience along the bottom edge of the fascia board and an upper end of the slots communicating with the attic space. In another embodiment, a plurality of spaced vent pockets are formed in the inside face and a slot is formed along the bottom edge of the fascia vent communicating with the vent pockets. In use, hot air vented from the attic is replaced by fresh air that flows through the fascia vent and into the attic space. | 02-25-2010 |
20110124280 | Ridge Vent with Powered Forced Air Ventilation - A ridge vent with powered forced air ventilation includes a ridge vent that is configured to be installed along the ridge of a roof covering an elongated ridge slot on either side of a ridge beam of the roof. Hot air from the attic below escapes by convection through the ridge slot and is expelled to ambient atmosphere through the ridge vent. A blower is mounted in a blower opening formed at a predetermined location along the ridge vent on one side of the ridge beam. The blower includes a blower housing forming an inlet within the attic and an outlet oriented to force air upwardly through the vent slot to be expelled through the ridge vent. A pair of baffles are hingedly secured to the housing adjacent its outlet and can be hinged up for dropping the blower through the blower opening during installation, and then hinged down and attached to a roof deck covering the blower opening and a portion of the ridge slot on the other side of the ridge beam. The baffles secure the blower and help to isolate its outlet from the attic space below. An impeller is disposed in the housing and is driven by an electric motor, which may be driven by electricity from a solar panel, electricity from a household electrical service, or both depending upon availability of sunlight and other conditions. | 05-26-2011 |
20110277394 | Fascia Vent - A fascia vent for a roof structure includes a fascia board for attachment along the lower ends of roof rafters that support a roof deck above an attic space. The fascia vent has an exposed outside face and an inside face at least partly exposed to the attic space. In one embodiment, a plurality of slots are formed along the inside face of the fascia board with a lower end of the slots communicating with ambience along the bottom edge of the fascia board and an upper end of the slots communicating with the attic space. In another embodiment, a plurality of spaced vent pockets are formed in the inside face and a slot is formed along the bottom edge of the fascia vent communicating with the vent pockets. In still another embodiment for installing along the longer rafter tails of wider rafters, the fascia board is wider and plunge cuts are made along the bottom edge of the fascia board to form a flow path to the vent pockets and thus to an attic space. In use, hot air vented from the attic is replaced by fresh air that flows through the fascia vent and into the attic space. | 11-17-2011 |
20140179220 | Contoured Mesh Ridge Vents - Ridge vents and deck covers are disclosed that have a fibrous mesh mat and a moisture barrier. The mesh mat may be contoured to define a variety of structures and may have regions of relatively higher fiber density and regions of relatively lower fiber density. Solar cells may be exposed on the ridge vents to collect solar energy when the vents are exposed to sunlight. | 06-26-2014 |
20150159378 | HIP VENT - A vent is disclosed that is particularly suited to use in ventilating attic spaces beneath a hip roof. The vent is configured to be installed along a hip of the roof overlying and covering a ventilation slot formed through the roof deck along the hip. The vent includes an elongated laterally flexible top panel from which baffle arrays depend. The baffle arrays are formed of a plurality of depending arcuately curved vanes that arc away from the vent. The vanes are aerodynamically shaped to redirect wind-blown rain and snow away from the vent and are configured to block the migration of rain and snow through the vent. A pair of spongy conformable filler strips is attached beneath the edge portions of the vent. The filler strips conform to the shapes of underlying shingles when the vent is installed to fill any gaps that otherwise might be formed between the vent and the shingles. A weather filter drapes over some of the baffle arrays to allow attic air to pass but prevent ingress of blown snowflakes and raindrops. | 06-11-2015 |