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| 20100008978 | NANOPARTICLES EFFECTIVE FOR INTERNALIZATION INTO CELLS - This invention provides antibodies that have improved affinity for the epidermal growth factor receptor (EGFR). In addition, this invention provides microparticles and nanoparticles comprising a plurality of EGFR affinity moieties that are effectively internalized by cells expressing an EGFR. | 01-14-2010 |
| 20100009390 | MUTANT ANTIBODIES WITH HIGH AFFINITY FOR EGFR - This invention provides antibodies that have improved affinity for the epidermal growth factor receptor (EGFR). In addition, this invention provides microparticles and nanoparticles comprising a plurality of EGFR affinity moieties that are effectively internalized by cells expressing an EGFR. | 01-14-2010 |
| 20100297004 | HIGH AFFINITY ANTI-PROSTATE STEM CELL ANTIGEN (PSCA) ANTIBODIES FOR CANCER TARGETING AND DETECTION - The present invention provides novel high affinity antibodies and fragments thereof that bind to the cancer antigen PSCA. The antibodies of the present invention may be used for cancer diagnosis, prognosis, treatment, visualization, and the like. The present invention also provides methods for the detection, visualization, and treatment of various cancers expressing PSCA. | 11-25-2010 |
| 20130209481 | Anti-Tumor Antigen Antibodies and Methods of Use - Antibodies that bind to tumor associated antigen CD44 or to tumor associated antigen EphA2, are disclosed herein, as well as related compositions and methods of use. Methods of use encompass cancer therapies, diagnostics, and screening methods. | 08-15-2013 |
| 20150239983 | HIGH AFFINITY ANTI-PROSTATE STEM CELL ANTIGEN (PSCA) ANTIBODIES FOR CANCER TARGETING AND DETECTION - The present invention provides novel high affinity antibodies and fragments thereof that bind to the cancer antigen PSCA. The antibodies of the present invention may be used for cancer diagnosis, prognosis, treatment, visualization, and the like. The Present invention also provides methods for the detection, visualization, and treatment of various cancers expressing PSCA. | 08-27-2015 |
| 20150343081 | ANTI-EPHA2 ANTIBODIES AND METHODS OF USE THEREOF - Antibodies that bind to tumor associated antigen CD44 or to tumor associated antigen EphA2, are disclosed herein, as well as related compositions and methods of use. Methods of use encompass cancer therapies, diagnostics, and screening methods. | 12-03-2015 |
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| 20100106082 | IN SITU TUBING MEASUREMENTS FOR INFUSION PUMPS - An infusion pump uses sensors and a computer program to detect tubing in a tube-loading section of the pump. The pump and the computer program also measures one or more of the tubing outer diameter, outer circumference, inner diameter, inner circumference, and tubing wall thickness. The infusion pump utilizes proximity sensors, such as an ultrasonic sensor, a capacitive sensor, or even an air-in-line sensor to detect proximity between two infusion pump surfaces, such as the surfaces that clamp the tubing in the pump, to determine thickness. At least one of the clamping surfaces is equipped with sensors to indicate contact length of the tubing with the surface. Using these measurements, the tubing wall thickness and inner diameter can be determined. Knowing the actual tubing inner diameter, increased volumetric accuracy is possible, up to a three or four percent improvement over present measurements. | 04-29-2010 |
| 20100229978 | INFUSION PUMP ACTUATORS, SYSTEM AND METHOD FOR CONTROLLING MEDICAL FLUID FLOWRATE - An infusion pump includes an actuator having an output shaft; a pump actuator having a length l | 09-16-2010 |
| 20120130676 | IN SITU TUBING MEASUREMENTS FOR INFUSION PUMPS - An infusion pump having a tubing clamping section including a movable and a stationary portion. The infusion pump includes at least one sensor for detecting a contact length of tubing within the movable and/or the stationary portion. The infusion pump includes a shuttle having a shuttle stationary and a shuttle moveable portion, and is configured to squeeze a length of the tubing between the shuttle portions. The infusion pump includes a motor connected to the shuttle moveable portion via a shaft. The motor moves the shuttle moveable portion towards and away from the shuttle stationary portion. The infusion pump includes a controller and an encoder that detects a position of the shaft. The controller converts the detected position into a travel distance of the shuttle moveable portion, and calculates a diameter and a thickness of the tubing based on the travel distance and the contact length of the tubing. | 05-24-2012 |
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| 20080254325 | System for transferring metal to electronic energy - Disclosed are a device and method for generating electrical energy. The device has a fuel cell that converts hydrogen gas to electricity; and a fuel cartridge in fluid communication with the fuel cell and containing a fuel which reacts with water to form the hydrogen gas. The fuel comprises a solid metal or alloy, and the fuel cartridge is configured such that the rate of hydrogen gas generation decreases automatically without consuming electricity as demand for the hydrogen gas decreases. | 10-16-2008 |
| 20080271377 | Combination Metal-Based and Hydride-Based Hydrogen Sources and Processes for Producing Hydrogen - A metal based hydrogen source contains metal such as Al, Zn, Mg that can react with water to produce hydrogen gas, borohydride such as sodium borohydride, potassium borohydride etc, and hydroxides such as NaOH and KOH etc. The hydrogen generation follows the following processes: First, metal aluminum reacts with water and hydroxide to produce hydrogen gas an heat, at the same time, hydroxide, the stabilizer of sodium borohydride, is consumed; As sodium borohydride is de-stabilized by the consuming of sodium hydroxide, hydrogen gas is produced through hydrolysis reaction of borohydride. The hydrolysis reaction can be accelerated by utilizing the heat that comes from aluminum's reaction with water. At the same time, hydroxides are partly or completely eliminated from the byproduct. The hydrogen gas produced may be used for any purpose. | 11-06-2008 |
| 20090214904 | Integrated Fuel and Fuel Cell Device - Described here is a device for generating electrical current via an electrochemical fuel cell that consumes hydrogen. The described device may be entirely or partially self-contained or may be made up of cooperating components. The device comprises at least and fuel and fuel cell components and those components may be integrated. The fuel is selected to produce hydrogen suitable for use in a variety of fuel cell designs that utilize hydrogen to produce electrical current. The fuel cell, in some variations, produces water and that water may be returned to the selected fuel source to create a self-sustaining supply of hydrogen for the fuel cell under load. The fuel cell may also contain a system for controlling the amount of water produced by the fuel cell that gets delivered to the solid fuel. | 08-27-2009 |
| 20100012499 | FUEL CELL CHARGER - A method and apparatus is described for recharging a fuel used to produce hydrogen for a hydrogen consuming device. The fuel can be NaBH | 01-21-2010 |
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| 20120093283 | METHOD FOR PLACING A/D CONVERTER, FRONT-LIT DETECTOR AND CT APPARATUS - A front-lit detector includes a collimator, an X-ray to visible light converter configured to convert X-rays to visible light after the X-rays pass through the collimator to irradiate the X-ray to visible light converter, a visible light to analog signal converter configured to cover the visible light into analog signals, a substrate on which the visible light to analog signal converter is placed, and an A/D converter configured to convert the analog signals into digital signals. | 04-19-2012 |
| 20130018214 | CATALYST COMPOSITION FOR OLIGOMERIZATION OF ETHYLENE AND PROCESSES OF OLIGOMERIZATIONAANM Zheng; MingfangAACI BeijingAACO CNAAGP Zheng; Mingfang Beijing CNAANM Li; WeizhenAACI BeijingAACO CNAAGP Li; Weizhen Beijing CNAANM Wang; HuaijieAACI BeijingAACO CNAAGP Wang; Huaijie Beijing CNAANM Liu; JunAACI BeijingAACO CNAAGP Liu; Jun Beijing CNAANM Zhang; HaiyingAACI BeijingAACO CNAAGP Zhang; Haiying Beijing CNAANM Zhou; YuAACI BeijingAACO CNAAGP Zhou; Yu Beijing CNAANM Li; TonglinAACI BeijingAACO CNAAGP Li; Tonglin Beijing CNAANM Zhao; LanAACI BeijingAACO CNAAGP Zhao; Lan Beijing CNAANM Wang; JilongAACI BeijingAACO CNAAGP Wang; Jilong Beijing CNAANM Wu; HongfeiAACI BeijingAACO CNAAGP Wu; Hongfei Beijing CNAANM Piao; YulingAACI BeijingAACO CNAAGP Piao; Yuling Beijing CNAANM Sui; JunlongAACI BeijingAACO CNAAGP Sui; Junlong Beijing CN - The present invention provides a catalyst composition for the ethylene oligomerization, which comprises 2-imino-1,10-phenanthroline coordinated iron (II), cobalt (II) or nickel (II) chloride as main catalyst and triethylaluminum as cocatalyst. The present invention also provides a process for oligomerization of ethylene is provided, wherein a catalyst composition comprising 2-imino-1,10-phenanthroline coordinated iron (II), cobalt (II) or nickel (II) chloride as main catalyst and triethylaluminum as cocatalyst is used, and the molar ratio of aluminum in the cocatalyst to central metal in the main catalyst ranges from 30 to less than 200. According to the present invention, another process for oligomerization of ethylene is also provided, wherein a catalyst composition comprising 2-imino-1,10-phenanthroline coordinated iron (II), cobalt (II) or nickel (II) chloride as main catalyst and triethylaluminum as cocatalyst is used, and the temperature of ethylene oligomerization ranges from −10 to 19° C. According to the present invention, the price of cocatalyst i.e. triethylaluminum, is low, just a fraction of that of methylaluminoxane, the amount of cocatalyst is therefore significantly reduced, with the catalytic activity is still acceptable, thus the cost of ethylene oligomerization is significantly reduced. In view of both the catalytic activity and the cost, the present invention is highly applicable in industry. | 01-17-2013 |
| 20130267708 | N ORTHO ACYL SUBSTITUTED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PROCESS FOR PREPARING AMINAL IRON (II) COMPLEXES THEREOF - Provided are a process for preparing an N ortho acyl substituted nitrogen-containing heterocyclic compound and an aminal iron (II) complex thereof, and the use of the complexes obtained by the process in an olefin oligomerization catalyst. The N ortho acyl substituted nitrogen-containing heterocyclic compound in the present invention is for example 2-acyl-1,10-phenanthroline or 2,6-diacetyl pyridine as shown in formula b, and the N ortho acyl substituted nitrogen-containing heterocyclic compound in the present invention is produced by a reaction of a precursor thereof in a substituted or unsubstituted nitrobenzene. Preferably the precursor shown in formula I in the present invention is produced by 1,10-phenanthroline reacting with trialkyl aluminum, or a halogenoalkyl aluminum R | 10-10-2013 |
| 20150369017 | EXPLORATION DRILLING SYSTEM AND METHOD FOR SUPPLYING POWER THERETO - A drilling system, comprising: a plurality of drilling drive systems; a fracturing drive system; a centralized power supply system electrically coupled to said drilling drive systems and said fracturing drive system to supply power thereto; and a plurality of distributed power supply systems electrically coupled to said drilling drive systems to supply additional power thereto during peak loading of a respective one of the plurality of drilling drive systems. | 12-24-2015 |
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| 20150024373 | MICROFLUIDIC CHIP - A microfluidic chip orients and isolates components in a sample fluid mixture by two-step focusing, where sheath fluids compress the sample fluid mixture in a sample input channel in one direction, such that the sample fluid mixture becomes a narrower stream bounded by the sheath fluids, and by having the sheath fluids compress the sample fluid mixture in a second direction further downstream, such that the components are compressed and oriented in a selected direction to pass through an interrogation chamber in single file formation for identification and separation by various methods. The isolation mechanism utilizes external, stacked piezoelectric actuator assemblies disposed on a microfluidic chip holder, or piezoelectric actuator assemblies on-chip, so that the actuator assemblies are triggered by an electronic signal to actuate jet chambers on either side of the sample input channel, to jet selected components in the sample input channel into one of the output channels. | 01-22-2015 |
| 20150111196 | MICROFLUIDIC CHIP - A microfluidic chip orients and isolates components in a sample fluid mixture by two-step focusing, where sheath fluids compress the sample fluid mixture in a sample input channel in one direction, such that the sample fluid mixture becomes a narrower stream bounded by the sheath fluids, and by having the sheath fluids compress the sample fluid mixture in a second direction further downstream, such that the components are compressed and oriented in a selected direction to pass through an interrogation chamber in single file formation for identification and separation by various methods. The isolation mechanism utilizes external, stacked piezoelectric actuator assemblies disposed on a microfluidic chip holder, or piezoelectric actuator assemblies on-chip, so that the actuator assemblies are triggered by an electronic signal to actuate jet chambers on either side of the sample input channel, to jet selected components in the sample input channel into one of the output channels. | 04-23-2015 |
