Patent application number | Description | Published |
20090242477 | Modified Substrate and Process for Production Thereof - The present invention is characterized in that a base material comprises ester groups in the main chain and/or in the side chain(s), and comprises a polymer having hydrophobic groups. Particularly, the hydrophobic groups can be introduced by irradiating the base material with a radiation during the base material contacts an aqueous solution of a monohydric alcohol or an aqueous solution of an alcohol having not less than 2 hydroxyl groups, which is a monomer or a polymer, and which has one or more carbon atoms between the carbon atoms to each of which the hydroxyl group is bound in the monomer or in each monomer constituting the polymer. | 10-01-2009 |
20100176048 | Substrate and method for production thereof - The present invention relates to a substrate including a compound having blood anticoagulation activity and a hydrophilic polymer compound, wherein the amount of elution of the compound having blood anticoagulation activity is less than 0.6 μg/ml, and a manufacturing method of a substrate, wherein after a compound having blood anticoagulation activity and a hydrophilic compound brought in contact with a substrate are irradiated with radiation, unreacted components are washed out. | 07-15-2010 |
20110017654 | SEPARATION MEMBRANE, METHOD OF PRODUCING THE SAME AND SEPARATION MEMBRANE MODULE USING THE SEPARATION MEMBRANE - A separation membrane includes a membrane comprising a polymer, characterized in that a functional layer is formed on the surface in one side of the membrane, the peak area percentage of carbon derived from ester group measured by the electron spectroscopy for chemical analysis (ESCA) on the surface of the preceding functional layer is 0.1% (by atomic number) or more but not more than 10 (% by atomic number), and the peak area percentage of carbon derived from ester group measured by the electron spectroscopy for chemical analysis (ESCA) on the surface opposite to the functional layer is not more than 10 (% by atomic number). A separation membrane module suffering from little sticking of organic matters, proteins, platelets and so on is provided with the separation membrane as a built-in membrane. | 01-27-2011 |
Patent application number | Description | Published |
20110117287 | Process for producing modified substrate - The present invention provides a modified substrate including a hydrophilic polymer wherein the soluble hydrophilic polymer ratio is 15 weight percent or less and the number of adhered human blood platelets is 10/4.3×10 | 05-19-2011 |
20130220912 | CARRIER FOR BLOOD COMPONENT ADSORPTION AND BLOOD COMPONENT ADSORPTION COLUMN - A carrier for blood component adsorption includes a water-insoluble carrier composed of a fiber or particle, the water-insoluble carrier having a surface to which a functional group(s) is/are introduced, the functional group(s) containing an acidic functional group selected from the group consisting of the sulfate group, sulfite group and sulfonate group; and containing an amino group; the fiber having a fiber diameter of, or the particle having a particle diameter of, 0.5 to 20 μm. | 08-29-2013 |
20130306544 | MEDICAL MATERIAL AND HOLLOW FIBER MEMBRANE MODULE - The present invention provides a medical material and a blood purification apparatus each having high anti-thrombotic properties and high safety. The apparatus is produced by incorporating therein a medical material which has a hydrophilic copolymerization polymer present on a surface thereof which is to be in contact with blood, wherein particulate protuberances each having a particle diameter of 50 nm or more are present on the surface which is to be in contact with blood at a density of 3 particles/μm | 11-21-2013 |
20140061121 | SEPARATION MEMBRANE, METHOD OF PRODUCING THE SAME AND SEPARATION MEMBRANE MODULE USING THE SEPARATION MEMBRANE - A separation membrane includes a membrane comprising a polymer, characterized in that a functional layer is formed on the surface in one side of the membrane, the peak area percentage of carbon derived from ester group measured by the electron spectroscopy for chemical analysis (ESCA) on the surface of the preceding functional layer is 0.1% (by atomic number) or more but not more than 10 (% by atomic number), and the peak area percentage of carbon derived from ester group measured by the electron spectroscopy for chemical analysis (ESCA) on the surface opposite to the functional layer is not more than 10 (% by atomic number). A separation membrane module suffering from little sticking of organic matters, proteins, platelets and so on is provided with the separation membrane as a built-in membrane. | 03-06-2014 |
20140206818 | CARRIER FOR ADSORPTION AND METHOD FOR PRODUCING SAME - An adsorptive carrier includes one or more high-molecular-weight compounds each of which includes two or more aromatic ring-containing repeating units, the aromatic rings being covalently bound to each other via a structure represented by Formula (I): | 07-24-2014 |
Patent application number | Description | Published |
20130327698 | CARRIER FOR BLOOD COMPONENT ADSORPTION AND BLOOD COMPONENT ADSORPTION COLUMN - A carrier for blood component adsorption enables selective and efficient adsorption removal of granulocytes and monocytes and, at the same time, enables adsorption removal of inflammatory cytokines. The carrier for blood component adsorption includes a water-insoluble carrier having a surface to which a functional group(s) containing a silyl group and an amino group is/are introduced. | 12-12-2013 |
20140256783 | SUBSTRATE AND METHOD FOR PRODUCTION THEREOF - The present invention relates to a substrate including a compound having blood anticoagulation activity and a hydrophilic polymer compound, wherein the amount of elution of the compound having blood anticoagulation activity is less than 0.6 μg/ml, and a manufacturing method of a substrate, wherein after a compound having blood anticoagulation activity and a hydrophilic compound brought in contact with a substrate are irradiated with radiation, unreacted components are washed out. | 09-11-2014 |
20150053609 | POLYSULFONE-BASED HOLLOW FIBER MEMBRANE AND HOLLOW FIBER MEMBRANE MODULE THAT PURIFIES BLOOD PREPARATIONS - A polysulfone-based hollow fiber membrane that purifies blood preparations, including a hydrophilic polymer on a surface thereof which contacts the blood preparation, wherein an abundance ratio of the hydrophilic polymer is from 40 to 60% by mass, and porosity at the surface is 8 to 30%. | 02-26-2015 |