Yan, US
Allen Yan, Reno, NV US
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20120273099 | REDUCED TOXICITY HYPERGOLIC PROPELLANTS - The disclosure described herein is a reduced toxicity rocket propellant comprising a liquid fuel and a liquid oxidizer that ignites spontaneously upon contact with each other. The rocket propellant includes a metal hydride catalyst. Multiple embodiments of the propellant include multiple compositions of liquid fuel. | 11-01-2012 |
Cong Yan, Carmel, IN US
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20120204274 | BITRANSGENIC MURINE MODEL FOR STUDYING MYELOPOIESIS, IMMUNITY AND TUMORIGENESIS - A myeloid-specific c-fms-rtTA/(TetO) | 08-09-2012 |
Dong Yan, Buffalo Grove, IL US
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20130226784 | SYSTEM AND METHOD FOR CREDIT BALANCE TRANSFER OFFER OPTIMIZATION - A computer based method for selecting a balance transfer pricing offer for an individual financial account. The method includes selecting a plurality of balance transfer offers, each balance transfer offer comprising balance transfer pricing and duration criteria, executing computer executable instructions comprising one or more predictive models that estimate for the individual financial account and each of the balance transfer offers a plurality of parameters such as a probability of a response as well as a plurality of financial parameters, scoring the estimate of the one or more predictive models to determine an expected financial benefit for each of the balance transfer offers, determining, for the individual financial account, an optimal balance transfer offer among the plurality of the balance transfer offers by way of maximizing the expected financial benefit based on a plurality of constraints, and assigning to the individual financial account the optimal balance transfer offer. | 08-29-2013 |
Fang Yan, Nashville, TN US
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20120165262 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISORDERS INVOLVING EPITHELIAL CELL APOPTOSIS - The present invention provides therapeutic and prophylactic compositions for use in treating and preventing disorders involved epithelial cell apoptosis, such as gastrointestinal disorders (e.g., inflammatory bowel disease, Crohn's disease or ulcerative colitis) in a subject, such as a human patient. | 06-28-2012 |
Fenglan Yan, St. Charles, MO US
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20120225050 | METHODS FOR IMPROVING GUT HEALTH - The present invention provides methods for improving gut health. In particular, the invention provides methods for improving gut health by improving the digestibility of dietary proteins, decreasing the flow of protein to the lower gastrointestinal tract, and/or decreasing the levels of | 09-06-2012 |
20140248258 | METHODS FOR IMPROVING GUT HEALTH - The present invention provides methods for improving gut health. In particular, the invention provides methods for improving gut health by improving the digestibility of dietary proteins, decreasing the flow of protein to the lower gastrointestinal tract, and/or decreasing the levels of | 09-04-2014 |
Fengting Yan, Columbus, OH US
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20130059892 | Compositions and Methods for Cancer Detection and Treatment - Disclosed herein are compositions and methods for cancer detection and treatment. Compounds that inhibit PRMT5 are contemplated, as are pharmaceutical compositions comprising a therapeutically effective amount of at least one PRMT5 inhibitor. In some embodiments pharmaceutical compositions further comprising at least one HDAC inhibitor are contemplated. Methods of treating disorders in a mammal by inhibiting PRMT5 by administering to a mammal, a therapeutically effective amount of a PRMT5 inhibitor are also disclosed. | 03-07-2013 |
Gai Yan, Baltimore, MD US
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20130142887 | USE OF HISTONE ACETYLTRANSFERASE INHIBITORS AS NOVEL ANTI-CANCER THERAPIES - The present invention provides methods for treating cancer comprising inhibiting the activity of p300/CBP histone acetyltransferase (HAT). Also provided are p300/CBP HAT inhibitors for treating a subject having cancer. In addition, the present invention includes biomarkers for p300/CBP HAT inhibition, which are used to i) monitor the effectiveness of cancer therapy, and ii) identify anti-cancer agents for use in combination therapy. | 06-06-2013 |
Gaofei Yan, Hallandale, FL US
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20140014767 | Self-Righting Frame And Aeronautical Vehicle - An aeronautical vehicle that rights itself from an inverted state to an upright state has a self-righting frame assembly has an apex preferably at a top of a central vertical axis. The apex provides initial instability to begin a self-righting process when the vehicle is inverted on a surface. A lift and stabilization panel extends across an upper portion of said frame to provide lift, drag and/or stability. A propulsion system can be located within a central void of the frame assembly and oriented to provide a lifting force. An electronics assembly is also carried by the self-righting frame for receiving remote control commands and is communicatively interconnected to the power supply for remotely controlling the aeronautical vehicle to take off, to fly, and to land on a supporting surface. The frame provides self-righting functionality and protection of elements carried therein. | 01-16-2014 |
Gaofei Yan, Sunrise, FL US
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20120018579 | SELF-RIGHTING FRAME AND AERONAUTICAL VEHICLE - An aeronautical vehicle that rights itself from an inverted state to an upright state has a self-righting frame assembly has a protrusion extending upwardly from a central vertical axis. The protrusion provides an initial instability to begin a self-righting process when the aeronautical vehicle is inverted on a surface. A propulsion system, such as rotor driven by a motor can be mounted in a central void of the self-righting frame assembly and oriented to provide a lifting force. A power supply is mounted in the central void of the self-righting frame assembly and operationally connected to the at least one rotor for rotatably powering the rotor. An electronics assembly is also mounted in the central void of the self-righting frame for receiving remote control commands and is communicatively interconnected to the power supply for remotely controlling the aeronautical vehicle to take off, to fly, and to land on a surface. | 01-26-2012 |
Guang Yan, Pocatello, ID US
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20140087056 | DIETARY FIBER SUPPLEMENTS FOR APPETITE SUPPRESSION - The present invention provides a composition of dietary fiber supplements for satiety enhancement and appetite suppression in treatment of overweight, obesity, or eating disorders. The composition of the dietary fiber supplements consist of at least one cationic polymer and at least one anionic polymer. The cationic polymers and the anionic polymers in the composition can be dissolved or dispersed in an aqueous solution. When the pH of the aqueous solution is lowered, such as the solution is ingested into the stomach with a gastric pH environment or the aqueous solution is added with some acidifying agents, the aqueous solution will turn into a gel. The formation of a gel from the aqueous solution after it being ingested into the stomach before a meal would provide a satiety enhancement and appetite suppression effect. | 03-27-2014 |
Guanhua Yan US
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20120180126 | Probable Computing Attack Detector - A probable computing attack detector monitors electrical power consumption of a computing device. Task data may be acquired for at least one task operating on the computing device. A predicted electrical power consumption may be calculated for the computing device employing a user-centric power model and the task data. A probable attack may be detected when the electrical power consumption disagrees with the predicted electrical power consumption by a determined margin. | 07-12-2012 |
Guojue Yan, Carpentersville, IL US
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20100289203 | PARALLEL CLAMP AND ACCESSORIES THEREFOR - An apparatus for securing a workpiece is provided. In one form, the apparatus is configured such that the clamping jaws of the apparatus lie flush against the workpiece and the pressure from the pressure application mechanism is distributed substantially equally over the surface of the workpiece in contact with the jaws of the apparatus. Additionally, the apparatus is provided with a brake mechanism which allows at least one of the clamping jaw members to be secured in a desired position on the elongated member without having to tilt the jaw member connected thereto. In another form, the apparatus may have two brake release mechanisms to account for the various positions the apparatus may be placed in with respect to a workpiece. The apparatus may also have mating structures which allow the apparatus to be connected to a work surface. In addition, the apparatus may also include a pivoting pressure application member handle to assist the user in applying or removing pressure to the workpiece. | 11-18-2010 |
Haijin Yan, Hainesville, IL US
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20120309430 | METHOD FOR IMPROVING DISCOVERY OF PREFERRED MOBILE COMPUTING LOCATIONS - A method for improving discovery of preferred mobile computing locations includes monitoring sensor data corresponding to a mobile computing device (MCD) and monitoring non-GPS network data implemented by the mobile computing device. Additionally, the method determines whether sensor data and non-GPS network data indicate that the mobile computing device is stationary within a cell site as well as scanning any network that the mobile computing device is electronically linked to. In short, the method discovers an improved preferred mobile computing location based on the sensor data and non-GPS network data that provide reliable information that the mobile computing device is stationary within the cell site. The sensor data and non-GPS network data are converged when several corresponding scans produce overlapping results. | 12-06-2012 |
20130331122 | METHOD FOR IMPROVING DISCOVERY OF PREFERRED MOBILE COMPUTING LOCATIONS - A method for improving discovery of preferred mobile computing locations includes monitoring sensor data corresponding to a mobile computing device (MCD) and monitoring non-GPS network data implemented by the mobile computing device. Additionally, the method determines whether sensor data and non-GPS network data indicate that the mobile computing device is stationary within a cell site as well as scanning any network that the mobile computing device is electronically linked to. In short, the method discovers an improved preferred mobile computing location based on the sensor data and non-GPS network data that provide reliable information that the mobile computing device is stationary within the cell site. The sensor data and non-GPS network data are converged when several corresponding scans produce overlapping results. | 12-12-2013 |
20130331123 | METHOD FOR IMPROVING DISCOVERY OF PREFERRED MOBILE COMPUTING LOCATIONS - A method for improving discovery of preferred mobile computing locations includes monitoring sensor data corresponding to a mobile computing device (MCD) and monitoring non-GPS network data implemented by the mobile computing device. Additionally, the method determines whether sensor data and non-GPS network data indicate that the mobile computing device is stationary within a cell site as well as scanning any network that the mobile computing device is electronically linked to. In short, the method discovers an improved preferred mobile computing location based on the sensor data and non-GPS network data that provide reliable information that the mobile computing device is stationary within the cell site. The sensor data and non-GPS network data are converged when several corresponding scans produce overlapping results. | 12-12-2013 |
20140051436 | METHODS AND DEVICES FOR IDENTIFYING LOCAL AREA NETWORKS | 02-20-2014 |
He Yan, Fort Collins, CO US
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20110231704 | METHODS, APPARATUS AND ARTICLES OF MANUFACTURE TO PERFORM ROOT CAUSE ANALYSIS FOR NETWORK EVENTS - Example methods, apparatus and articles of manufacture to perform root cause analysis for network events are disclosed. An example method includes retrieving a symptom event instance from a normalized set of data sources based on a symptom event definition; generating a set of diagnostic events from the normalized set of data sources which potentially cause the symptom event instance, the diagnostic events being determined based on dependency rules; and analyzing the set of diagnostic events to select a root cause event based on root cause rules. | 09-22-2011 |
20130051248 | HIERARCHICAL ANOMALY LOCALIZATION AND PRIORITIZATION - Methods, apparatus and articles of manufacture for hierarchical anomaly localization and prioritization are disclosed. An example method disclosed herein comprises obtaining reported status for a plurality of nodes of a hierarchical topology, the reported status for a particular node being at least one of normal, abnormal or indeterminate, and determining a subset of root cause abnormal nodes, a root cause abnormal node included in the subset of root cause abnormal nodes having a total number of abnormal direct descendent nodes and indeterminate direct descendent nodes that is greater than a number of normal direct descendent nodes of the root cause abnormal node. | 02-28-2013 |
20130185591 | METHODS, APPARATUS AND ARTICLES OF MANUFACTURE TO PERFORM ROOT CAUSE ANALYSIS FOR NETWORK EVENTS - Example methods, apparatus and articles of manufacture to perform root cause analysis for network events are disclosed. An example method includes retrieving a symptom event instance from a normalized set of data sources based on a symptom event definition; generating a set of diagnostic events from the normalized set of data sources which potentially cause the symptom event instance, the diagnostic events being determined based on dependency rules; and analyzing the set of diagnostic events to select a root cause event based on root cause rules. | 07-18-2013 |
Hong Yan US
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20130138569 | Protecting Identities of Users to Whom Advertising is Targeted - A system environment supporting one or more advertisers and one or more ad publishers provides a means of sharing user-targeted advertisement. One or more hashing modules in the system environment provide the advertisers and ad publishers a means of sharing this information without revealing a user's personally identifiable information (PII). If a lossy hash is chosen, then an advertiser can communicate targeted advertisements to an ad publisher without revealing any PII to the ad publisher that the ad publisher did not already know. | 05-30-2013 |
Jianhua Yan, Naperville, IL US
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20110151445 | ALLELIC DISORDERS CAUSED BY MUTATIONS IN TRPV4 - The present invention provides methods, kits, and compositions for detecting mutations in transient receptor potential cation channel, subfamily V, member 4 (TRPV4). In particular, mutations are detected in TRPV4 to detect diseases such as scapuloperoneal spinal muscular atrophy (SPSMA) and hereditary motor and sensory neuropathy type IIC (HMSN IIC) or Charcot-Marie-Tooth disease type 2C (CMT2C). | 06-23-2011 |
20130183671 | ALLELIC DISORDERS CAUSED BY MUTATIONS IN TRPV4 - The present invention provides methods, kits, and compositions for detecting mutations in transient receptor potential cation channel, subfamily V, member 4 (TRPV4). In particular, mutations are detected in TRPV4 to detect diseases such as scapuloperoneal spinal muscular atrophy (SPSMA) and hereditary motor and sensory neuropathy type IIC (HMSN IIC) or Charcot-Marie-Tooth disease type 2C (CMT2C). | 07-18-2013 |
Jin Yan, Orlando, FL US
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20120307178 | DISPLAY DEVICE - A display device includes a display module, a light source module and a guiding optical film. The display module includes a first substrate, a second substrate and a display medium. The light source module generates directional light. The display module has a vertical electric field. The display medium is optically isotropic, and the display medium is optically anisotropic when driven by the vertical electric field. The directional light is not perpendicular to the first substrate when the directional light enters the display nodule. The directional light is not perpendicular to the second substrate when the directional light exits the display module. The guiding optical film is disposed on the second substrate and has a light incident surface and a light emitting surface. After the directional light exits the guiding optical film, emitting light is formed, and the emitting light and the light emitting surface has an included angle there between. | 12-06-2012 |
20150036080 | Optical Film and Display Device Having the Same - An optical film and a display device having the same are provided. The optical film has a light input face, a light output face opposite to the light input face, and a light-output structure disposed on the light output face. The light-output structure includes a plurality of light output microstructures such as prisms disposed side by side along a first direction on the light output face. Each prism has a first quadrilateral cross section parallel to the first direction. A first side of the quadrilateral cross section is connected to the light output face and includes a first angle with the light output face, wherein the first angles of the prisms continuously arranged have angle values varying in a periodic manner. | 02-05-2015 |
Jun Yan, Annandale, VA US
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20090297486 | Survival, Differentiation and Structural Integration Of Human Neural Stem Cells Grafted Into the Adult Rat Spinal Cord - The present invention provides methods and compositions for treating spinal cord diseases and injuries. The methods involve transplanting neural stem cells which have been previously expanded in vitro into a patient such that the cells can ameliorate the disease or injury. The stem cells to be transplanted are derived from spinal cord tissue. | 12-03-2009 |
20150086511 | SURVIVAL, DIFFERENTIATION AND STRUCTURAL INTEGRATION OF HUMAN NEURAL STEM CELLS GRAFTED INTO THE ADULT RAT SPINAL CORD - The present invention provides methods and compositions for treating spinal cord diseases and injuires. The methods involve transplanting neural stem cells which have been previously expanded in vitro into a patient such that the cells can ameliorate the disease or injury. The stem cells to be transplanted are derived from spinal cord tissue. | 03-26-2015 |
Jun Yan, Louisville, KY US
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20090047288 | Glucan compositions and methods of enhancing CR3 dependent neutrophil-mediated cytotoxicity - A 25 kD β-glucan composition is described herein that effects the CR3-dependent priming of neutrophils and can promote neutrophil killing of iC3b-opsonized targets. Also described herein are methods of enhancing neutrophil cytotoxicity locally at the site of the tumor. | 02-19-2009 |
20090074761 | Therapeutic beta-glucan combinations - A therapeutic composition for treating a proliferative disorder includes a VEGF antagonist and β-glucan. VEGF is overexpressed in some tumor types. The efficacy of treatment with VEGF antagonists capable of activating complement in combination with β-glucan is significantly increased. | 03-19-2009 |
Jun Yan, Cincinatti, OH US
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20090027748 | MEMS Oscillator Having A Combined Drive Coil - A MEMS oscillator, such as a MEMS scanner, has an improved and simplified drive scheme and structure. Drive impulses may be transmitted to an oscillating mass via torque through the support arms. For multi-axis oscillators drive signals for two or more axes may be superimposed by a driver circuit and transmitted to the MEMS oscillator. The oscillator responds in each axis according to its resonance frequency in that axis. The oscillator may be driven resonantly in some or all axes. Improved load distribution results in reduced deformation. A simplified structure offers multi-axis oscillation using a single moving body. Another structure directly drives a plurality of moving bodies. Another structure eliminates actuators from one or more moving bodies, those bodies being driven by their support arms. | 01-29-2009 |
20090134319 | Scanned Beam Display and Method of Operating - A MEMS oscillator, such as a MEMS scanner, has an improved and simplified drive scheme and structure. Drive impulses may be transmitted to an oscillating mass via torque through the support arms. For multi-axis oscillators drive signals for two or more axes may be superimposed by a driver circuit and transmitted to the MEMS oscillator. The oscillator responds in each axis according to its resonance frequency in that axis. The oscillator may be driven resonantly in some or all axes. Improved load distribution results in reduced deformation. A simplified structure offers multi-axis oscillation using a single moving body. Another structure directly drives a plurality of moving bodies. Another structure eliminates actuators from one or more moving bodies, those bodies being driven by their support arms. | 05-28-2009 |
Kathy Wei Yan, Chandler, AZ US
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20110084388 | REDUCING UNDERFILL KEEP OUT ZONE ON SUBSTRATE USED IN ELECTRONIC DEVICE PROCESSING - Electronic devices and methods for fabricating electronic devices are described. One method includes providing a substrate with a die attach area, and forming a layer on the substrate outside of the die attach area. The layer may be formed from a fluoropolymer material. The method also includes coupling a die to the substrate in the die attach area, wherein a gap remains between the die and the die attach area. The method also includes placing an underfill material in the gap and adjacent to the layer on the substrate. Examples of fluoropolymer materials which may be used include polytetrafluoroethylene (PTFE) and perfluoroalkoxy polymer resin (PFA). Other embodiments are described and claimed. | 04-14-2011 |
Kenny Yan, Asheville, NC US
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20130190097 | Golf Training Aid - A golf training aid comprises a body including a top surface and a bottom surface. The top surface comprises a club shaft groove. The bottom surface comprises an index finger groove, a middle finger groove and a separation bulge between the two index and middle finger grooves. The body comprises an elastomeric material having sufficient flexibility so the club shaft groove generally conforms to a golf club shaft and the index and middle finger grooves generally conform to the index and middle fingers of a user when the body is positioned between the user's hand and the golf club shaft with a user's hand gripping the golf club shaft. | 07-25-2013 |
Liang Zeng Yan, Carmel, IN US
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20080300177 | CYCLIC PEPTIDE CXCR4 ANTAGONISTS - Provided are lactam-cyclized peptide CXCR4 antagonists useful in the treatment of cancers, rheumatoid arthritis, pulmonary fibrosis, and HIV infection. | 12-04-2008 |
20100130409 | CYCLIC PEPTIDE CXCR4 ANTAGONISTS - Provided are lactam-cyclized peptide CXCR4 antagonists useful in the treatment of cancers, rheumatoid arthritis, pulmonary fibrosis, and HIV infection. | 05-27-2010 |
Miin Jen Yan, Dublin, OH US
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20110283963 | ACCOMMODATING PISTON SEAT FOR DIFFERENTIAL-STROKE CYCLE ENGINES - A piston seat method and apparatus for a differential-stroke cycle combustion engine, the combustion engine including one or more two-part pistons, each two-part piston having a first piston part and a second piston part. The apparatus comprising: a piston seat cover operatively associated with the first piston part, the piston seat cover being adapted for abutting engagement with the second piston part; wherein, upon abutting engagement, the seat cover is adapted to move relative to the first piston part, thereby at least partially absorbing impact forces applied between the first piston part and the second piston part. | 11-24-2011 |
Miin Jeng Yan, Dublin, OH US
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20130014713 | DIFFERENTIAL-STROKE INTERNAL COMBUSTION ENGINE - An apparatus and method for a differential stroke combustion engine. The combustion engine including one or more two-part pistons, each two-part piston having a first piston part and a second piston part. The apparatus comprising: piston-lever element mechanically coupled to the second piston part; a plurality of cam-followers assemblies selectively coupleable with the piston-lever element for controlling operation of the second piston part; and wherein selective engagement of one or more cam-followers assemblies defines an operational mode of the second piston part. | 01-17-2013 |
Mingdi Yan, Lake Oswego, OR US
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20080214410 | IMMOBILIZATION OF DISCRETE MOLECULES - Embodiments of a method for covalently immobilizing one or more discrete molecules on a substrate and embodiments of substrates having covalently-immobilized discrete molecules are disclosed. Embodiments of the method can include exposing a substrate to a functionalizing reagent to form a functionalized substrate and exposing the functionalized substrate to a solution comprising the molecule to be immobilized. A reaction-energy source then can be used to activate the functionalizing reagent and covalently bond one or more of the molecules to the substrate. All or a substantial portion of the unbonded molecules then can be removed. Controlling the concentration of the functionalizing reagent to which the substrate is exposed allows the density of the bonding sites on the substrate to be reduced so that, after removal of the unbonded molecules, at least one of the bonded molecules remains on the substrate spatially isolated from any other bonded molecules. | 09-04-2008 |
20100028559 | Method for functionalizing materials and devices comprising such materials - Devices comprising functionalized materials, and embodiments of a method for making and using such devices, are disclosed. Exemplary devices include ophthalmic devices, nanoparticles, quartz crystal microbalances, microarrays, and nanocomposites. In particular embodiments, device surfaces are modified with monomers and/or polymers, typically carbohydrate monomers and/or polymers. Embodiments of a method for making and using such devices are disclosed. Monomers and/or polymers are covalently bonded to surfaces using functionalized perhalophenylazides. In some embodiments, device surfaces are functionalized with a perhalophenylazide. One or more monomers and/or polymers subsequently are covalently bonded to the device surface using the perhalophenylazide. In other embodiments, monomers and/or polymers are derivatized with a functionalized perhalophenylazide. The derivatized monomers and/or polymers then are covalently bonded to the device surface using the perhalophenylazide. In some embodiments, graphite is functionalized with perhalophenylazide to produce a functionalized graphene sheet. In other embodiments, graphene sheets are covalently attached to functionalized substrates. | 02-04-2010 |
Philip Yan, Vernon Hills, IL US
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20080311043 | Uses and compositions for treatment of psoriatic arthritis - The invention provides methods, uses and compositions for the treatment of psoriatic arthritis. The invention describes methods and uses for treating psoriatic arthritis, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to psoriatic arthritis in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment of psoriatic arthritis in a subject. | 12-18-2008 |
20090304682 | Multiple-variable dose regimen for treating TNFa-related disorders - Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase. | 12-10-2009 |
20130122011 | Multiple-variable dose regimen for treating TNFa-related disorders - Multiple-variable dose methods for treating TNFα-related disorders, including Crohn's disease and psoriasis, comprising administering TNFα inhibitors, including TNFα antibodies, are described. Multiple-variable dose methods include administration of a TNF-inhibitor in an induction or loading phase followed by administration of the agent in a maintenance or treatment phase, wherein the TNF-inhibitor is administered in a higher dosage during the induction phase. | 05-16-2013 |
20130243763 | TREATMENT OF HIDRADENITIS SUPPURATIVA (HS) USING TNFalpha ANTIBODIES - Methods of treating TNFα-related disorders comprising administering TNFα inhibitors, including TNFα antibodies are described. | 09-19-2013 |
20130243786 | TREATMENT OF JUVENILE RHEUMATOID ARTHRITIS (JRA) - Methods of treating TNFα-related disorders comprising administering TNFα inhibitors, including TNFα antibodies are described. | 09-19-2013 |
20140248215 | USES AND COMPOSITIONS FOR TREATMENT OF PSORIATIC ARTHRITIS - The invention provides methods, uses and compositions for the treatment of psoriatic arthritis. The invention describes methods and uses for treating psoriatic arthritis, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to psoriatic arthritis in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment of psoriatic arthritis in a subject. | 09-04-2014 |
20140286939 | TREATMENT OF TNFALPHA RELATED DISORDERS - Methods of treating TNFα-related disorders comprising administering TNFα inhibitors, including TNFα antibodies are described. | 09-25-2014 |
20140286940 | TREATMENT OF TNFALPHA RELATED DISORDERS - Methods of treating TNFα-related disorders comprising administering TNFα inhibitors, including TNFα antibodies are described. | 09-25-2014 |
20140286941 | TREATMENT OF TNFALPHA RELATED DISORDERS - Methods of treating TNFα-related disorders comprising administering TNFα inhibitors, including TNFα antibodies are described. | 09-25-2014 |
20150050216 | Uses and Compositions for Treatment of Psoriasis - The invention provides methods, uses and compositions for the treatment of psoriasis. The invention describes methods and uses for treating psoriasis, wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof, is used to treat psoriasis in a subject. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment psoriasis in a subject. | 02-19-2015 |
20150071938 | Use of TNFAlpha Inhibitor for Treatment of Psoriasis - The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarthritis. | 03-12-2015 |
Pingkun Yan, Bethesda, MD US
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20130281839 | VISUALIZATION OF CATHETER OF THREE-DIMENSIONAL ULTRASOUND - An image-guided system employs an X-ray imaging device ( | 10-24-2013 |
Qilang Yan, Portland, OR US
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20080235651 | Method and apparatus for determining an optical model that models the effects of optical proximity correction - One embodiment provides a system that can enable a designer to determine the effects of subsequent processes at design time. During operation, the system may receive a test layout and an optical model that models an optical system, but which does not model the effects of subsequent processes, such as optical proximity correction (OPC). The system may generate a first dataset using the test layout and the optical model. Next, the system may apply OPC to the test layout, and generate a second dataset using the corrected test layout and the optical model. The system may then use the first dataset and the second dataset to adjust the optical model to obtain a second optical model that models the effects of subsequent processes. | 09-25-2008 |
Qiliang Yan, Portland, OR US
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20080219590 | Method and system for correlating physical model representation to pattern layout - One embodiment of the present invention provides a system that reduces computational complexity in simulating an image resulting from an original mask and an optical transmission system. During operation, the system obtains a set transmission cross coefficient (TCC) kernel functions based on the optical transmission system, and obtains a set of transmission functions for a representative pattern which contains features representative of the original mask. The system constructs a new set of kernel functions based on the TCC kernel functions and the transmission functions for the representative pattern, wherein responses to the new kernel functions in a resulting image corresponding to the representative pattern are substantially uncorrelated with one another. The system further produces an intensity distribution of a resulting image corresponding to the original mask based on the new kernel functions, thereby facilitating prediction of a layout that can be produced from the original mask. | 09-11-2008 |
20080276211 | Method and apparatus for determining a process model using a 2-D-pattern detecting kernel - One embodiment provides a system for determining an improved process model that models one or more semiconductor manufacturing processes. During operation, the system can receive a first process model. Next, the system can receive a 2-D-pattern detecting kernel which can detect 2-D patterns. The system can then receive a second set of empirical data which is associated with 2-D patterns in a test layout. Next, the system can determine an improved process model using the first process model, the 2-D-pattern detecting kernel, the test layout, and the second set of empirical data. | 11-06-2008 |
20100086196 | METHOD AND APPARATUS FOR DETERMINING AN OPTICAL THRESHOLD AND A RESIST BIAS - One embodiment of the present invention provides techniques and systems for determining modeling parameters for a photolithography process. During operation, the system can receive a layout. Next, the system can determine an iso-focal pattern in the layout. The system can then determine multiple aerial-image-intensity values in proximity to the iso-focal pattern by convolving the layout with multiple optical models, wherein the multiple optical models model the photolithography process's optical system under different focus conditions. Next, the system can determine a location in proximity to the iso-focal pattern where the aerial-image-intensity values are substantially insensitive to focus variations. The system can then use the location and the associated aerial-image-intensity values to determine an optical threshold and a resist bias. The optical threshold and the resist bias can then be used for modeling the photolithography process. | 04-08-2010 |
20110202891 | EVALUATING THE QUALITY OF AN ASSIST FEATURE PLACEMENT BASED ON A FOCUS-SENSITIVE COST-COVARIANCE FIELD - One embodiment of the present invention provides a system that determines an assist feature placement within a post-optical proximity correction (post-OPC) mask layout. During operation, the system receives a set of target patterns which represent a set of polygons in a pre-OPC mask layout. The system then constructs a focus-sensitive cost function based on the target patterns, wherein the focus-sensitive cost function represents an amount of movement of post-OPC contours of the target patterns in response to changes in focus condition of the lithography system. Note that the contours of the target patterns substantially coincide with the edges of set of the polygons. Next, the system computes a cost-covariance field (CCF field) based on the focus-sensitive cost function, wherein the CCF field is a two-dimensional (2D) map representing changes to the focus-sensitive cost function due to an addition of a pattern at a given location within the post-OPC mask layout. Finally, the system generates assist features for the post-OPC mask layout based on the CCF field. | 08-18-2011 |
20140032199 | Fast 3D Mask Model Based on Implicit Countors - Computer-readable medium and methods for photolithographic simulation of scattering. A design layout comprising a layout polygon is received. A skeleton representation of a mask shape that is created responsive to e-beam writing of the layout polygon is generated. The skeleton representation is defined by a plurality of skeleton points. Individual scattering patterns for the skeleton points are selected from a lookup table of pre-determined scattering patterns. Each of the individual scattering patterns representing an amount of optical scattering for a corresponding one of the skeleton points. A simulated wafer image is produced responsive to the individual scattering patterns. | 01-30-2014 |
Qinyi Yan, Davie, FL US
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20130008803 | Methods and Systems for Measurement of Tear Glucose Levels - A sensor system for determining glucose concentration in a tear fluid sample includes a working electrode including an immobilized glucose oxidase enzyme portion for reacting with glucose in the tear fluid sample, and a selectivity portion for enhancing the selectivity for glucose over electroactive interferent species in the tear fluid sample. Alternatively, a vessel for receiving the tear fluid sample may include the enzyme portion on an inner wall thereof. A reference electrode is disposed adjacent the working electrode, wherein the electrochemical reaction of the enzyme portion with glucose in the tear fluid sample generates a current related to the glucose concentration in the tear fluid sample. | 01-10-2013 |
20140305796 | METHODS AND SYSTEMS FOR MEASUREMENT OF TEAR GLUCOSE LEVELS - A sensor system for determining glucose concentration in a tear fluid sample includes a working electrode including an immobilized glucose oxidase enzyme portion for reacting with glucose in the tear fluid sample, and a selectivity portion for enhancing the selectivity for glucose over electroactive interferent species in the tear fluid sample. Alternatively, a vessel for receiving the tear fluid sample may include the enzyme portion on an inner wall thereof. A reference electrode is disposed adjacent the working electrode, wherein the electrochemical reaction of the enzyme portion with glucose in the tear fluid sample generates a current related to the glucose concentration in the tear fluid sample. | 10-16-2014 |
Qiuming Yan, Ashburn, VA US
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20100114682 | Systems and Methods for Advertising on Content-Screened Web Pages - According to one aspect of the present disclosure, a method is provided for advertising on a content-screened web page. The method includes receiving an impression request for a URL for which an advertising impression is desired; screening HTML content of a web page identified by the URL; generating a rating for the URL based on the HTML content of the web page; assigning the rating to the impression request; and serving an advertising impression on the web page based on the rating. | 05-06-2010 |
20140222554 | SYSTEMS AND METHODS FOR ADVERTISING ON CONTENT-SCREENED WEB PAGES - According to one aspect of the present disclosure, a method is provided for advertising on a content-screened web page. The method includes receiving an impression request for a URL for which an advertising impression is desired; screening HTML content of a web page identified by the URL; generating a rating for the URL based on the HTML content of the web page; assigning the rating to the impression request; and serving an advertising impression on the web page based on the rating. | 08-07-2014 |
Riqiang Yan, Pepper Pike, OH US
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20080299596 | Substrates and assays for beta-secretase activity - The present invention is directed to novel substrates for Hu-Asp. More particularly, the invention provides peptide substrates and fusion polypeptide substrates comprising a β-secretase cleavage site. Methods and compositions for making and using the peptides are disclosed. | 12-04-2008 |
20090075316 | Alzheimer's Disease Secretase, APP Substrates Therefor and Uses Therefor - The present invention provides the enzyme and enzymatic procedures for cleaving the β secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays. The invention further provides a modified APP protein and associated nucleic acids, peptides, vectors, cells, and cell isolates, and assays that are particularly useful for identifying candidate therapeutics for treatment or prevention of Alzheimer's disease. | 03-19-2009 |
20110294149 | Alzheimer's Disease Secretase, APP Substrates Therefor, and Uses Therefor - The present invention provides the enzyme and enzymatic procedures for cleaving the β secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and cell isolates and assays. The invention further provides a modified APP protein and associated nucleic acids, peptides, vectors, cells, and cell isolates, and assays that are particularly useful for identifying candidate therapeutics for treatment or prevention of Alzheimer's disease. | 12-01-2011 |
Rong Yan US
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20120259919 | Using Polling Results as Discrete Metrics for Content Quality Prediction Model - A social networking system presents content items to users, who then provide feedback regarding pairs of content items. The feedback includes a selection of a content item of the pair of content items that was preferred by the user over the other content item. The social networking system uses this information to train a predictive model that scores content items based on quality. The content items may be advertisements. The social networking system uses the pair-wise comparisons of the advertisements to determine feedback coefficients in an advertising quality score prediction model using regression analysis of the pair-wise comparisons for each predictive factor in the model. In this way, the pair-wise comparisons are used to train the prediction model to understand which advertisements are more enjoyable than others. A feedback coefficient for each predictive factor may be computed based on the preferences received from the group of users. | 10-11-2012 |
20130254283 | Targeting Stories Based On Influencer Scores - A story describing an activity performed by an interacting user is distributed to viewing users according to the influencer scores for the viewing users. Each influencer score can be calculated based at least in part on the influence of a viewing user on those users connected to the viewing user, and on the influencer scores for the users connected to the viewing user. Based on the determined influencer scores, at least one of the viewing users can be provided with the story describing the activity performed by the interacting user. | 09-26-2013 |
Rusen Yan, Mishawaka, IN US
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20130342279 | METHODS AND APPARATUS FOR TERAHERTZ WAVE AMPLITUDE MODULATION - A wave amplitude modulator for modulating a transmitted electromagnetic wave includes one or multiple self-gated capacitively coupled pair(s) of electron layers such as semiconductor or semimetal layers. Two electrical contacts are placed to each layer of electrons of the self-gated pair(s), and a power source is electrically connected to them. The power source, by varying the voltage applied between layers of electrons, tunes the electron density thereof, thereby adjusting the optical conductivity thereof, and the change in the optical conductivity of the layers of electrons causes an amplitude modulation of the transmitted electromagnetic wave passing through the capacitively coupled layers of electrons. | 12-26-2013 |
Shikui Yan, Knoxville, TN US
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20130026353 | Conical Water-Equivalent Phantom Design for Beam Hardening Correction in Preclinical Micro-CT - Apparatuses, methods, and computer-readable mediums are provided that utilize a phantom to correct attenuation due to beam hardening. The phantom includes a calibration tip attached to a proximal end of a portion. The portion has a diameter that increases incrementally from the proximal end of the portion towards a distal end of the portion (e.g., a substantially conical shape, a substantially convex shape, a substantially concave shape, or a series of adjacent steps). In another embodiment, a method is provided in which the phantom is scanned and an image of the phantom is reconstructed. Thereafter, an x-ray path length and estimated attenuation coefficient are calculated. A sum of expected coefficients are also calculated. The calculations are used to generate an algorithm for beam hardening coefficients. | 01-31-2013 |
20130100345 | Imaging System Warp Correction with Phantom Assembly - A device for imaging system warp correction includes an object including an imaging phantom, the object being configured for placement of the imaging phantom adjacent a scanning interface of a detector, and a mounting cap coupled to the object and configured to be secured to the detector to establish the placement of the imaging phantom adjacent the scanning interface of the detector. The mounting cap includes a plurality of alignment features configured to align the object and the mounting cap. | 04-25-2013 |
20130329217 | Laser System for Aligning a Bed Transport Mechanism in an Imaging System - A system for aligning a bed of an imaging system with an imaging plane. The system includes a laser device which generates a laser beam and a target element having a target detecting surface. The system also includes a reflective element which receives the laser beam. The reflective element includes a reflective detecting surface for detecting a first position of the laser beam. A first parameter of the bed is adjusted until the laser beam is positioned on a first center portion of the reflective detecting surface. In addition, the laser beam is reflected to the target detecting surface to detect a second position of the laser beam. A second parameter of the bed is adjusted until the laser beam is positioned on a second center portion of the target detecting surface to orient the bed substantially perpendicular to the imaging plane. | 12-12-2013 |
Shoubao Yan, Tucson, AZ US
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20090174479 | High-voltage differential amplifier and method using low voltage amplifier and dynamic voltage selection - A differential amplifier ( | 07-09-2009 |
Wang Yan, Gainesville, FL US
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20130273446 | HYDROGEN OXIDATION AND GENERATION OVER CARBON FILMS - An electrode comprises an acid treated, cathodically cycled carbon-comprising film or body. The carbon consists of single walled nanotubes (SWNTs), pyrolytic graphite, microcrystalline graphitic, any carbon that consists of more than 99% sp | 10-17-2013 |
Wei Yan, Memphis, TN US
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20120110896 | METHOD FOR WET TORREFACTION OF A BIOMASS - A process for increasing the energy density of a biomass, which includes establishing a temperature and pressure within a reaction chamber that includes water and is at or above a desired reaction condition wherein the desired reaction condition is sufficient to increase the energy density of a reacted biomass; introducing a biomass into the reaction chamber such that the desired reaction condition is maintained or equilibrates thereto; and subjecting the biomass to the desired reaction condition for an amount of time effective to increase the energy density of the reacted biomass relative to the biomass prior to reaction. | 05-10-2012 |
20140262727 | Rapid Production of Hydrothermally Carbonized Biomass via Reactive Twin-Screw Extrusion - A system for the production of carbonized biomass that includes an infeed for accepting biomass feed material and an associated twin screw extruder. A water heater is connected with respect to at least one inlet along a length of the twin screw extruder and a pressure sustaining valve is connected at an outlet of the twin screw extruder. | 09-18-2014 |
Wenchang Yan, Duluth, GA US
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20110282943 | SYSTEMS AND METHODS FOR DETERMINING VALUE OF SOCIAL MEDIA PAGES - Systems and methods for evaluating the effectiveness of social media pages. Users of social media systems review and publish various kinds of content on social media pages, including various messages, audio clips, video clips, polls, web links, etc. A social media page evaluation system hosted on a physical server or a cloud receives a social media page that is to be evaluated, and provides results of an evaluation process. The evaluation process involves processing of various criteria and parameters that characterize engagements and interactions between users of social media pages. Results of an evaluation process include qualitative and quantitative attributes in connection with evaluating the effectiveness of published content on social media pages. Such results are useful for purposes of enriching content in social media pages, resulting in greater network traffic due to increased engagements and interaction among users of social media pages. | 11-17-2011 |
Wengui Yan, Stuttgart, AR US
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20100132062 | Rice Mutant Allele - A rice mutant allele designated Rc-g is disclosed. The invention relates to the Rc-g nucleotide sequence, the amino acid sequence, rice seeds containing the mutant allele Rc-g, to rice plants containing the mutant allele Rc-g and to methods for producing a rice plant containing the mutant allele Rc-g produced by crossing a rice plant containing allele Rc-g with itself or another rice variety. The invention further relates to hybrid rice seeds and hybrid rice plants containing mutant allele Rc-g. | 05-27-2010 |
Xiangying Yan, Portland, OR US
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20130336305 | PERSISTENT LOGICAL DATA TUNNELS - Embodiments of the present disclosure describe methods, computer-readable media and system configurations for data delivery among wireless machine-to-machine (“M2M”) and/or machine-type-communication (“MTC”) devices. A method may include receiving, from a plurality of wireless devices (e.g., user equipment or subscriber unit devices), a plurality of uplink data packets, and routing uplink data packets from a subset of the plurality of wireless devices into a logical data tunnel leading to an access gateway. The logical data tunnel may be persistent across sessions of the subset of the plurality of wireless devices. Additionally or alternatively, a method may include incorporating an M2M/MTC payload into data for establishing a connection between a wireless device and a radio access network (“RAN”), so that the wireless device may thereafter enter into an idle mode. Other embodiments may be described and/or claimed. | 12-19-2013 |
Xiaodong Yan, New Milford, CT US
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20120283163 | COPPER CLEANING AND PROTECTION FORMULATIONS - A cleaning composition and process for cleaning post-chemical mechanical polishing (CMP) residue and contaminants from a microelectronic device having said residue and contaminants thereon. The cleaning compositions include novel corrosion inhibitors. The composition achieves highly efficacious cleaning of the post-CMP residue and contaminant material from the surface of the microelectronic device without compromising the low-k dielectric material or the copper interconnect material. | 11-08-2012 |
Xiao-Hai Yan, Newark, DE US
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20090022359 | Vegetation index image generation methods and systems - Methods and systems for generating a vegetation index image of a geographic region are disclosed by the present invention. The vegetation index image is generated by identifying one or more obscured locations within the geographic region, determining a vegetation index value for each location within the geographic region, replacing the determined vegetation index value for each obscured location with a predetermined replacement value for that location, and generating a vegetation index image based on the predetermined replacement values for the obscured locations and the determined vegetation index values for the non-obscured locations. | 01-22-2009 |
20090187369 | Estimation of subsurface thermal structure using sea surface height and sea surface temperature - A method of determining a subsurface temperature in a body of water is disclosed. The method includes obtaining surface temperature anomaly data and surface height anomaly data of the body of water for a region of interest, and also obtaining subsurface temperature anomaly data for the region of interest at a plurality of depths. The method further includes regressing the obtained surface temperature anomaly data and surface height anomaly data for the region of interest with the obtained subsurface temperature anomaly data for the plurality of depths to generate regression coefficients, estimating a subsurface temperature at one or more other depths for the region of interest based on the generated regression coefficients and outputting the estimated subsurface temperature at the one or more other depths. Using the estimated subsurface temperature, signal propagation times and trajectories of marine life in the body of water are determined. | 07-23-2009 |
Xin Yan, West Lafayette, IN US
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20130280819 | SYNCHRONIZATION OF ION GENERATION WITH CYCLING OF A DISCONTINUOUS ATMOSPHERIC INTERFACE - The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface. | 10-24-2013 |
20140051180 | SYNCHRONIZATION OF ION GENERATION WITH CYCLING OF A DISCONTINUOUS ATMOSPHERIC INTERFACE - The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface. | 02-20-2014 |
Xin Yan, Bloomington, IN US
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20120279570 | SOLUBLE GRAPHENE NANOSTRUCTURES AND ASSEMBLIES THEREFROM - Disclosed herein is a method for preparing large soluble graphenes. The method comprises attaching one or more hindering groups to the graphene, which can prevent face-to-face graphene stacking by reducing the effects of inter-graphene attraction. The large graphenes can absorb a wide spectrum of light from UV to near infrared, and are useful in photovoltaic devices and sensitizers in nanocrystalline solar cells. | 11-08-2012 |
Xingzhong Yan, Brookings, SD US
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20090002919 | Organic branched and hyperbranched systems for high dielectric and capacitance applications - An organic dielectric material comprises a branched and/or hyperbranched macromolecule having delocalized electrons. Such macro-molecular organic material systems have desirable delocalized charge and optionally one or more micro-crystalline regions. Organic dielectric materials include, for example, branched polyanilines and phthalocyanines. Delocalized excitations within the macromolecular framework of the organic dielectric material may be used in various applications, such as light harvesting, nonlinear optical, quantum optical, and electronic applications, e.g., capacitors. Electrical devices may comprise such dielectric materials, including capacitors that have very high energy density, storage, and transfer. Also provided are methods of preparing such materials. | 01-01-2009 |
Xuxu Yan, Palm Beach Gardens, FL US
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20130022542 | RADIOLABELLED ROTENONE DERIVATIVES AND THEIR USE IN SPECT IMAGING - The present application discloses a compound of formula (I) or (II): | 01-24-2013 |
Yajun Yan, Athens, GA US
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20130130340 | BIOSYNTHESIS OF CAFFEIC ACID AND CAFFEIC ACID DERIVATIVES BY RECOMBINANT MICROORGANISMS - Microorganisms are genetically engineered to synthesize caffeic acid from simple carbon sources via a tyrosine intermediate by means of a dual pathway that utilizes both endogenous and engineered enzymatic activities. | 05-23-2013 |
20140134690 | MICROBES AND METHODS FOR PRODUCING 1-PROPANOL - Provided herein are microbes metabolically engineered to produce 1-propanol from a 1,2-propanediol intermediate. The microbes may include one or two pathways for production of 1-propanol from a 1,2-propanediol intermediate. Also provided herein are methods for using the microbes for the production of 1-propanol. | 05-15-2014 |
20140363858 | METHODS FOR HYDROXYLATING PHENYLPROPANOIDS - Provided herein are methods for producing an ortho-hydroxylated phenylpropanoid. In one embodiment the method includes culturing a microbe that includes HpaBC activity in the presence of a phenylpropanoid substrate. Also provided are genetically engineered microbes engineered to have greater levels of HpaB and/or HpaC than a control microbe. | 12-11-2014 |
20140370557 | GENETICALLY ENGINEERED MICROBES AND METHODS FOR PRODUCING 4-HYDROXYCOUMARIN - Provided herein are methods for the biosynthesis of 4-hydroxycoumarin. In one embodiment, provided herein are genetically engineered microbes that include a metabolic pathway for the production of 4-hydroxycoumarin. Also provided are methods for using the genetically engineered microbes to produce 4-hydroxycoumarin, and using the 4-hydroxycoumarin as the starting point for the synthesis of other compounds. | 12-18-2014 |
Yajun Yan, Bogart, GA US
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20130203141 | PRODUCTION OF 1,4-BUTANEDIOL BY RECOMBINANT MICROORGANISMS - Provided herein are metabolically-modified microorganisms useful for producing 1,4-butanediol. | 08-08-2013 |
20130288325 | BIOFUEL AND CHEMICAL PRODUCTION BY RECOMBINANT MICROORGANISMS VIA FERMENTATION OF PROTEINACEOUS BIOMASS - Provided herein are metabolically modified microorganisms characterized by having an increased keto-acid flux when compared with the wild-type organism and comprising at least one polynucleotide encoding an enzyme that when expressed results in the production of a greater quantity of a chemical product when compared with the wild-type organism. The recombinant microorganisms are useful for producing a large number of chemical compositions from various nitrogen containing biomass compositions and other carbon sources. More specifically, provided herein are methods of producing alcohols, acetaldehyde, acetate, isobutyraldehyde, isobutyric acid, n-butyraldehyde, n-butyric acid, 2-methyl-1-butyraldehyde, 2-methyl-1-butyric acid, 3-methyl-1-butyraldehyde, 3-methyl-1-butyric acid, ammonia, ammonium, amino acids, 2,3-butanediol, 1,4-butanediol, 2-methyl-1,4-butanediol, 2-methyl-1,4-butanediamine, isobutene, itaconate, acetoin, acetone, isobutene, 1,5-diaminopentane, L-lactic acid, D-lactic acid, shikimic acid, mevalonate, polyhydroxybutyrate (PHB), isoprenoids, fatty acids, homoalanine, 4-aminobutyric acid (GABA), succinic acid, malic acid, citric acid, adipic acid, p-hydroxy-cinnamic acid, tetrahydrofuran, 3-methyl-tetrahydrofuran, gamma-butyrolactone, pyrrolidinone, n-methylpyrrolidone, aspartic acid, lysine, cadeverine, 2-ketoadipic acid, and/or S-adenosyl-methionine (SAM) from a suitable nitrogen rich biomass. | 10-31-2013 |
Yan Yan, Cheshire, CT US
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20130189258 | THERAPEUTIC METHODS USING ANTI-CD200 ANTIBODIES - The present disclosure relates to anti-CD200 antibodies and to use of the antibodies in methods for treating autoimmune disorders and cancer. Also featured are biomarkers for use in selecting or prescribing a treatment modality for a patient with an autoimmune disorder and/or cancer. In addition, the disclosure features methods of treatment using an anti-CD200 antibody in combination with one or more additional therapeutic agents such as an anti-CD20 therapeutic agent. | 07-25-2013 |
20130202602 | BIOMARKERS OF IMMUNOMODULATORY EFFECTS IN HUMANS TREATED WITH ANTI-CD200 ANTIBODIES - The present disclosure relates to anti-CD200 antibodies (e.g., variant anti-CD200 antibodies having decreased or no effector function) and to biomarkers for use in a variety of diagnostic and therapeutic methods, e.g., determining whether a human has been administered one or more of the antibodies at a dose sufficient to induce a desired immunomodulatory effect in the human and/or selecting an appropriate dosing schedule for a patient. | 08-08-2013 |
20150079613 | ATYPICAL HEMOLYTIC UREMIC SYNDROME BIOMARKER PROTEINS - The disclosure provides biomarker proteins, a change in the concentration or activity level of which are associated with atypical hemolytic uremic syndrome (aHUS) or clinically meaningful treatment of aHUS with a complement inhibitor. Also provided are compositions and methods for interrogating the concentration and/or activity of one or more of the biomarker proteins in a biological fluid. The compositions and methods are useful for, among other things, evaluating risk for developing aHUS, diagnosing aHUS, determining whether a subject is experiencing the first acute presentation of aHUS, monitoring progression or abatement of aHUS, and/or monitoring response to treatment with a complement inhibitor or optimizing such treatment. | 03-19-2015 |
Yanfa Yan, Littleton, CO US
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20100263717 | Low Temperature Junction Growth Using Hot-Wire Chemical Vapor Deposition - A system and a process for forming a semi-conductor device, and solar cells ( | 10-21-2010 |
Yilin Yan US
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20120107857 | Di- and Poly-Ubiquitin Deubiquitinase Substrates and Uses Thereof - Methods for detection of the activity of proteolytic enzymes, particularly isopeptidases, are disclosed. | 05-03-2012 |
Yuan-Yong Yan US
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20130041096 | POLYHEDRAL-MODIFIED POLYMER - A macromolecule including a polymer and a polyhedral radical chemically bonded to a terminus of the polymer provides numerous processing and performance advantages. Further functionalization of this macromolecule also is described as being advantageous in certain circumstances. Methods of providing, functionalizing, and utilizing the macro-molecule also are provided. | 02-14-2013 |
Yushan Yan, Hockessin, DE US
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20130260282 | EXTENDED TWO DIMENSIONAL METAL NANOTUBES AND NANOWIRES USEFUL AS FUEL CELL CATALYSTS AND FUEL CELLS CONTAINING THE SAME - Metal nanotubes are provided comprising a composition having formula (M | 10-03-2013 |
20140004402 | DOUBLE-MEMBRANE TRIPLE-ELECTROLYTE REDOX FLOW BATTERY DESIGN | 01-02-2014 |
20140004403 | MULTIPLE-MEMBRANE MULTIPLE-ELECTROLYTE REDOX FLOW BATTERY DESIGN | 01-02-2014 |
20140107237 | CATION-STRUNG SIDE CHAIN POLYMERS USEFUL IN HYDROXIDE/ANION EXCHANGE MEMBRANES - This invention provides a family of cation-strung polymers capable of forming membranes having exceptional hydroxide ionic conductivity as well as low water uptake and methods of making the same. The invention also provides for using these cation-strung polymers to manufacture membranes useful in HEMFC fuel cells and other devices such as electrolysis, solar hydrogen generation, redox flow battery, dialysis, reverse osmosis, forward osmosis, pervaporation, ion exchange, sensor, and gas separation. | 04-17-2014 |
20140326611 | MEMBRANES AND CATALYSTS FOR FUEL CELLS, GAS SEPARATION CELLS, ELECTROLYZERS AND SOLAR HYDROGEN APPLICATIONS - Oxygen reduction catalysts for fuel cells are provided. The catalyst can be based on platinum-coated palladium nanotubes, or multiple twinned, crystalline silver nanowires. Also provided is a method of removing carbon dioxide using a membrane having basic functional groups, and a method of water electrolysis using a membrane having basic functional groups. | 11-06-2014 |
Zhe Yan, Lakewood, CO US
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20120009212 | CONJUGATES UTILIZING PLATFORM TECHNOLOGY FOR STIMULATING IMMUNE RESPONSE - Templated conjugates created from naturally-occurring protein sequences found in pathogens, such as viruses, are disclosed. The sequences are “templated” into a consensus coiled-coil sequence in order to form a two-stranded antigen suitable for immunization of a subject. | 01-12-2012 |
20120014972 | INFLUENZA VIRUS COMPOSITIONS AND METHODS FOR UNIVERSAL VACCINES - The disclosure relates at least in part to embodiments of compositions and methods including vaccines for protection against multiple serologically distinct strains of influenza virus. This disclosure provides significant advances and addresses important needs in the influenza vaccine field. | 01-19-2012 |
20140154282 | CONJUGATES UTILIZING PLATFORM TECHNOLOGY FOR STIMULATING IMMUNE RESPONSE - Templated conjugates created from naturally-occurring protein sequences found in pathogens, such as viruses, are disclosed. The sequences are “templated” into a consensus coiled-coil sequence in a platform in order to form a two-stranded antigen suitable for immunization of a subject. | 06-05-2014 |
Zhen Yan, Charlottesville, VA US
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20110152317 | PREVENNTING THE OCCURRENCE OF OBESITY - Administration of autophagy inhibitor (e.g. 400 mg chloroquine daily) prevents occurrence of obesity and insulin resistance in human subject on prolonged high-fat diet. | 06-23-2011 |
Zhen-Xing Yan US
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20110170070 | LIGHT-MIXING MODULE AND OPTICAL PROJECTION SYSTEM - A light-mixing module includes a first plate, a second plate, a first dichroic mirror, a second dichroic mirror, and a third dichroic mirror. The first dichroic mirror is disposed between the first plate and the second plate and is substantially perpendicular to the first plate and the second plate. The second dichroic mirror is disposed on a first side of the first dichroic mirror. The second dichroic mirror forms an angle with the first dichroic mirror and is substantially perpendicular to the first plate and the second plate. The third dichroic mirror is disposed on a second side of the first dichroic mirror and is substantially perpendicular to the first plate and the second plate. The third dichroic mirror is substantially parallel with the second dichroic mirror. The second dichroic mirror and the third dichroic mirror together form a fourth dichroic mirror, and at least one of the first dichroic mirror and the fourth dichroic mirror has a bevel gradient dichroic film. | 07-14-2011 |
Zhiquan Yan, Richmond, VA US
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20110259943 | Hermetically Sealed Paperboard Container with Enhanced Barrier Performance - A hermetically sealed paperboard container including a container body component including upper and lower ends, the body component being formed from a blank including a paperboard layer having first and second major sides, a first sealant layer on the first major side, a barrier layer on the second major side, and a second sealant layer on the barrier layer, wherein the blank includes first and second longitudinal ends, the first longitudinal end being skived to a predetermined thickness for a predetermined width, the skived portion being folded over onto the blank and heat-sealed to the first sealant layer to form a folded first longitudinal end, and wherein the body component includes an overlapped seam including the folded first longitudinal end positioned inside the second longitudinal end, a bottom component sealed to the lower end; and a lid component hermetically sealed to the upper end. | 10-27-2011 |
20120104078 | Hermetically Sealed Paperboard Container with Enhanced Barrier Performance - A hermetically sealed paperboard container including a container body component including upper and lower ends, the body component being formed from a blank including a paperboard layer having first and second major sides, a first sealant layer on the first major side, a barrier layer on the second major side, and a second sealant layer on the barrier layer, wherein the blank includes first and second longitudinal ends, the first longitudinal end being skived to a predetermined thickness for a predetermined width, the skived portion being folded over onto the blank and heat-sealed to the first sealant layer to form a folded first longitudinal end, and wherein the body component includes an overlapped seam including the folded first longitudinal end positioned inside the second longitudinal end, a bottom component sealed to the lower end; and a lid component hermetically sealed to the upper end. | 05-03-2012 |
Zhiquan Q. Yan, Richmond, VA US
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20120298733 | Hermetically Sealed Paperboard Container - A hermetically-sealed paperboard container is disclosed that may be produced using a conventional converting machine but at a converting temperature of at least 93° C. lower than a conventional converting temperature. The formation of pin holes or rupture on the barrier structure during the converting process can be significantly reduced, resulting in the hermetically-sealed paperboard container with enhanced barrier performances. | 11-29-2012 |
Zhiquan Quentin Yan, Richmond, VA US
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20110168771 | HERMETICALLY SEALED PAPERBOARD CONTAINERS WITH ENHANCED BARRIER PERFORMANCE - A hermetically sealed paperboard container with enhanced barrier and seal performances is disclosed that may be produced by a more effective and economical process for the in-plant system. The container includes a container body component, a bottom, and a top lid hermetically sealed to the body component. The container body is formed from a blank comprising a paperboard ( | 07-14-2011 |
Ziying Yan, Iowa City, IA US
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20080226600 | Adeno-associated viruses and uses thereof - The invention provides an isolated and purified DNA molecule comprising at least one DNA segment, a biologically active subunit or variant thereof, of a circular intermediate of adeno-associated virus, which DNA segment confers increased episomal stability, persistence or abundance of the isolated DNA molecule in a host cell. The invention also provides a composition comprising at least two adeno-associated virus vectors. | 09-18-2008 |
20080249050 | Compounds and methods to enhance rAAV transduction - Agents and methods to alter rAAV transduction are provided. | 10-09-2008 |
20090241203 | Transgenic animal models of disease - The present invention provides transgenic, large non-human animal models of diseases and conditions, as well as methods of making and using such animal models in the identification and characterization of therapies for the diseases and conditions. | 09-24-2009 |
20090241206 | METHODS FOR CLONING FERRETS AND TRANSGENIC FERRET MODELS FOR DISEASES - The invention provides a transgenic Mustelidae in which a gene associated with a human disease or condition comprises a targeted genetic modification, and uses thereof. Also provided is a method to cryopreserve Mustelidae embryos or cells, and to enhance the number of live offspring from cryopreserved Mustelidae embryos. | 09-24-2009 |
20110054247 | METHODS FOR CLONING FERRETS AND TRANSGENIC FERRET MODELS FOR DISEASES - The invention provides a transgenic Mustelidae in which a gene associated with a human disease or condition comprises a targeted genetic modification, and uses thereof. Also provided is a method to cryopreserve Mustelidae embryos or cells, and to enhance the number of live offspring from cryopreserved Mustelidae embryos. | 03-03-2011 |
20120180141 | Transgenic Animal Models of Disease - The present invention provides transgenic, large non-human animal models of diseases and conditions, as well as methods of making and using such animal models in the identification and characterization of therapies for the diseases and conditions. | 07-12-2012 |