Patent application number | Description | Published |
20090048274 | PYRAZOLO[3,4-d]PYRIMIDINE DERIVATIVES - Disclosed are novel pyrazolo[3,4-d]pyrimidine derivatives that are inhibitors of Raf kinase. These compounds and their pharmaceutically-acceptable salts and esters are anti-proliferative agents useful in the treatment or control of proliferative disorders such as solid tumors, in particular breast tumor, colon tumor, lung tumor, prostate tumor, and melanoma. Also disclosed are a composition and a unit dose formulation comprising such a compound, or a pharmaceutically-acceptable salt or ester thereof, methods for making such compounds, and methods for using such compounds, or their pharmaceutically-acceptable salts or esters, in the treatment of proliferative disorders. | 02-19-2009 |
20090111789 | CHIRAL CIS-IMIDAZOLINES - There are provided compounds of the formula | 04-30-2009 |
20090318408 | HALO-SUBSTITUTED PYRIMIDODIAZEPINES - The present invention provides PLK1 inhibitor compounds of formula I: | 12-24-2009 |
20100152190 | Substituted Pyrrolidine-2-Carboxamides - There are provided compounds of the formula | 06-17-2010 |
20100160308 | Thiazolyl-Benzimidazoles - The invention is directed to compounds of formula (1) | 06-24-2010 |
20110086854 | NOVEL N-SUBSTITUTED-PYRROLIDINES AS INHIBITORS OF MDM2-P-53 INTERACTIONS - There are provided compounds of the formula | 04-14-2011 |
20110130398 | SPIROINDOLINONE PYRROLIDINES - There are provided compounds of the formula | 06-02-2011 |
20110269809 | SPIROINDOLINONE PYRROLIDINES - There are provided compounds of the formula | 11-03-2011 |
20120010235 | N-SUBSTITUTED PYRROLIDINES - Compounds of formula | 01-12-2012 |
20120046306 | Substituted Heteroaryl Spiropyrrolidine MDM2 Antagonists - There are provided compounds of the general formula | 02-23-2012 |
20120065210 | SUBSTITUTED HEXAHYDROPYRROLO[1,2-C]IMIDAZOLONES - There are provided compounds of formula I | 03-15-2012 |
20120071499 | Substituted Spiro[3H-Indole-3,6'(5'H)-[1H]Pyrrolo[1,2c]Imidazole-1',2(1H,2'H)-diones - There are provided compounds of the formula | 03-22-2012 |
20130053410 | SUBSTITUTED HETEROARYL 2',3',7',7A'-TETRAHYDROSPIRO[PYRROLE-3,6'-PYRROLO[1,2-C]IMIDAZOLE]-1',2(1- H,5'H)-DIONE - There are provided compounds of the formula | 02-28-2013 |