Patent application number | Description | Published |
20130140416 | Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 06-06-2013 |
20140053891 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A PV module framing and coupling system which enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array and a cable management system that holds, directs, organizes, and otherwise manages cables, wires, cord, and similar components of and relating to a PV array. | 02-27-2014 |
20140158184 | Skirt and Other Devices for Photovoltaic Arrays - A skirt and other devices for photovoltaic arrays, as well as photovoltaic arrays with a skirt(s) and/or other device(s) installed, related modules, and foothold devices and systems are herein disclosed. Various such embodiments include one or more array skirt(s), T-locks, grip(s), inside and outside corner cap(s), array trim(s), pest abatement screen(s), wire clip(s), foothold(s), groove adaptor bracket(s), magnetic skirt embodiment(s), as well as other structures and embodiments which are herein disclosed. | 06-12-2014 |
20140182662 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - The method and apparatus for forming and mounting a photovoltaic (PV) array of this invention is disclosed and provides, without limitation, (i) a PV module framing and coupling system which enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array and (ii) an ancillary device attachment bracket, system, and method. One embodiment may provide a slidable parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement, thereby enabling the formation of a PV array with improved structural load distribution. Another embodiment may provide a photovoltaic module accessory bracket, comprising: a substantially rigid plate comprising a flexible spring tab; a first ear substantially rigidly positioned on the plate; a second ear positioned on the spring tab; wherein the spring tab flexes backward away from the plate during connection to a frame of a photovoltaic module to allow the first ear to engage the frame, and a forward force applied to the spring tab locks the second ear to the frame. | 07-03-2014 |
20140326838 | Apparatus, System, and Method for Photovoltaic-Related Wire Management - A flexible wire clip dimensioned to be snapped into a side groove on a photovoltaic module frame, wherein the wire clip flexes during installation such that a catch moves away from a frame-receiving slot and slides upwardly against a side edge of a photovoltaic module frame so that a frame member of a photovoltaic module frame can be inserted into the frame-receiving slot, and wherein the wire clip returns to a substantially non-flexed position after it has been snapped into the side groove of a photovoltaic module frame. | 11-06-2014 |
Patent application number | Description | Published |
20090191586 | ENZYME EXPRESSION METHODS AND COMPOSITIONS - Methods for expressing active enzymes are described that involve co-expressing a first enzyme with a second enzyme that has an enzymatic activity that reverses a modification on the first enzyme and/or for identification of soluble and/or active catalytic domains by systematic variation of fragment lengths around catalytic domain boundaries. | 07-30-2009 |
20100324065 | Compounds and methods for development of Ret Modulators - Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and structural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands. | 12-23-2010 |
20110005152 | STRUT RUNNER MEMBER AND ASSEMBLY USING SAME FOR MOUNTING ARRAYS ON ROOFTOPS AND OTHER STRUCTURES - A strut runner includes a member extending lengthwise in a first direction, where the member includes an underlying panel and one or more walls that extend from the panel. The member may be configured to at least partially support the panel array while being integrated or directly connected to the underlying structure. Additionally, the strut runner may include one or more peripheral extensions that extend a distance outward from the body. | 01-13-2011 |
20110173900 | MOUNTING ASSEMBLY FOR ARRAYS AND OTHER SURFACE-MOUNTED EQUIPMENT - A mounting system is provided for supporting equipment such as solar module arrays on a rooftop or other underlying surface. The mounting system includes a pipe, and a grasp section. These couple to a base that is extended into or otherwise integrated with the underlying surface. The pipe may be coupled so as to extend a height from the underlying surface. The grasp section is coupled to a top section of the pipe and is structured to secure to a section of the solar module array when the solar module array is installed on the underlying surface. | 07-21-2011 |
20110174360 | RACK ASSEMBLY FOR MOUNTING SOLAR MODULES - A rack assembly is provided for mounting solar modules over an underlying body. The rack assembly may include a plurality of rail structures that are arrangeable over the underlying body to form an overall perimeter for the rack assembly. One or more retention structures may be provided with the plurality of rail structures, where each retention structure is configured to support one or more solar modules at a given height above the underlying body. At least some of the plurality of rail structures are adapted to enable individual rail structures to be sealed over the underlying body so as to constrain air flow underneath the solar modules. Additionally, at least one of (i) one or more of the rail structures, or (ii) the one or more retention structures are adjustable so as to adapt the rack assembly to accommodate solar modules of varying forms or dimensions. | 07-21-2011 |
20130020267 | RACK ASSEMBLY FOR MOUNTING SOLAR MODULES - A rack assembly is provided for mounting solar modules over an underlying body. The rack assembly may include a plurality of rail structures that are arrangeable over the underlying body to form an overall perimeter for the rack assembly. One or more retention structures may be provided with the plurality of rail structures, where each retention structure is configured to support one or more solar modules at a given height above the underlying body. At least some of the plurality of rail structures are adapted to enable individual rail structures o be sealed over the underlying body so as to constrain air flow underneath the solar modules. Additionally, at least one of (i) one or more of the rail structures, or (ii) the one or more retention structures are adjustable so as to adapt the rack assembly to accommodate solar modules of varying forms or dimensions. | 01-24-2013 |
20130303534 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR - Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases. | 11-14-2013 |
20140037617 | KINASE MODULATION, AND INDICATIONS THEREFOR - The present disclosure provides methods of using protein kinase inhibitors for treating diseases and conditions, including diseases and conditions associated with activity of any protein kinase selected from Fms protein kinase including any mutations thereof, Kit protein kinase any mutations thereof, Flt-3 protein kinase any mutations thereof and combinations thereof. | 02-06-2014 |
Patent application number | Description | Published |
20140299179 | Photovoltaic Array Mounting Apparatus, Systems, and Methods - A photovoltaic array, including: (a) supports laid out on a surface in rows and columns; (b) photovoltaic modules positioned on top of the supports; and (c) fasteners connecting the photovoltaic modules to the supports, wherein the supports have an upper pedestal surface and a lower pedestal surface such that the photovoltaic modules are positioned at a non-horizontal angle when edges of the photovoltaic modules are positioned on top of the upper and lower pedestal surfaces, and wherein a portion of the fasteners rotate to lock the photovoltaic modules onto the supports. | 10-09-2014 |
20140339179 | PHOTOVOLTAIC MODULE FRAME - A photovoltaic module frame having hollow sections into which male ends of a corner key are received such that two frame sections can be connected together in orthogonal directions. The male ends of the corner key may have teeth thereon. Once so engaged, a tool head may be applied to the corner formed by the adjacent frame sections. The tool head may create indentations in the profiles that engage the teeth of the corner keys within the frame sections, thereby forming a corner of a module frame. | 11-20-2014 |
20140360558 | Pivot Framing System For Dual Glass Photovoltaic Modules - A photovoltaic module assembly in which frame members are affixed by sealant onto opposite bottom edges of a dual glass photovoltaic laminate to provide a module combining the strength advantages of framed modules with the advantages of frameless dual glass photovoltaic modules. | 12-11-2014 |
20150013756 | PIVOT-FIT FRAME, SYSTEM AND METHOD FOR PHOTOVOLTAIC MODULES - A system and apparatus are disclosed including PV modules having a frame allowing quick and easy assembling of the PV modules into a PV array in a sturdy and durable manner. In examples of the present technology, the PV modules may have a grooved frame where the groove is provided at an angle with respect to a planar surface of the modules. Various couplings may engage within the groove to assemble the PV modules into the PV array with a pivot-fit connection. Further examples of the present technology operate with PV modules having frames without grooves, or with PV modules where the frame is omitted altogether. | 01-15-2015 |
20150033658 | APPARATUS FOR FORMING AND MOUNTING A PHOTOVOLTAIC ARRAY - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 02-05-2015 |
20150040965 | Ground Mount Structure With Mounting Assemblies And Central Quick-Mount Rail - A solar array having three rails with the central rail having upward and downward facing pivot connectors, with top and bottom photovoltaic modules being pivot mounted onto the shared central rail such that the two photovoltaic modules are supported by three mounting rails. | 02-12-2015 |
20150040967 | PIVOT-FIT FRAME, SYSTEM AND METHOD FOR PHOTOVOLTAIC MODULES - A system and apparatus are disclosed including PV modules having a frame allowing quick and easy assembling of the PV modules into a PV array in a sturdy and durable manner. In examples of the present technology, the PV modules may have a grooved frame where the groove is provided at an angle with respect to a planar surface of the modules. Various couplings may engage within the groove to assemble the PV modules into the PV array with a pivot-fit connection. Further examples of the present technology operate with PV modules having frames without grooves, or with PV modules where the frame is omitted altogether. | 02-12-2015 |
20150068590 | APPARATUS FOR FORMING AND MOUNTING A PHOTOVOLTAIC ARRAY - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 03-12-2015 |
20150069198 | SOLAR PANEL ATTACHMENT SYSTEM - A method, system and apparatus are disclosed regarding an attachment system for solar equipment, sometimes referred to as a flashing device allowing quick and easy assembling of the solar equipment into an array or other combination in a sturdy and durable manner. In examples of the present technology, a flashing device may include a flashing plate which may contain one or more raised features to further direct and control the flow of liquid over the flashing plate. The flashing device may also contain a fluid restrictor such as a seal or part of a seal usually held within an aperture of a block having a skyward facing essentially or substantially flat surface. One or more various items of solar equipment may be attached to the essentially flat surface of the block. Also disclosed are adjustable mounting feet which may be installed in connection with other solar equipment. | 03-12-2015 |
20150075100 | Flashing System For Mounting Photovoltaic Arrays Onto Tile Roofs - A tile hook and flashing assembly, having: (a) a lower flashing; (b) an upper flashing; (c) a tile hook; and (d) a seal, wherein tile hook extends through an aperture passing between overlapping portions of the upper and lower flashings, and wherein the seal extends across the aperture and seals around the tile hook. | 03-19-2015 |
20150075589 | Low-Slope Mounted Photovoltaic Array - A photovoltaic array mounting system for a low-slope roof having interchangeable first and second bases, with a short leg extending from the first base at a non-vertical angle and a long leg extending from the second base at a non-vertical angle, wherein the short and long legs support opposite sides of a photovoltaic module such that the module is held at a non-horizontal angle, and wherein rock-in connectors are provided on top of the short and long legs permitting fast and easy system installation. | 03-19-2015 |
20150075590 | PIVOT-FIT FRAME, SYSTEM AND METHOD FOR PHOTOVOLTAIC MODULES - A system and apparatus are disclosed including PV modules having a frame allowing quick and easy assembling of the PV modules into a PV array in a sturdy and durable manner. In examples of the present technology, the PV modules may have a grooved frame where the groove is provided at an angle with respect to a planar surface of the modules. Various couplings may engage within the groove to assemble the PV modules into the PV array with a pivot-fit connection. Further examples of the present technology operate with PV modules having frames without grooves, or with PV modules where the frame is omitted altogether. | 03-19-2015 |
Patent application number | Description | Published |
20090203541 | MSP AND ITS DOMAINS AS FRAMEWORKS FOR NOVEL BINDING MOLECULES - Disclosed are compositions and methods relating to the use of MSP94 proteins and its domains as frameworks for novel binding molecules, including screening assays for the identification of novel binding molecules. | 08-13-2009 |
20090304719 | ACTIVATABLE BINDING POLYPEPTIDES AND METHODS OF IDENTIFICATION AND USE THEREOF - The present disclosure provides activatable binding polypeptides (ABPs), which contain a target binding moiety (TBM), a masking moiety (MM), and a cleavable moiety (CM). The present disclosure provides activatable antibody compositions, which contain a TBM containing an antigen binding domain (ABD), a MM and a CM. Furthermore the present disclosure also provides ABPs which contain a first TBM, a second TBM and a CM. The ABPs exhibit an “activatable” conformation such that at least one of the TBMs is less accessible to target when uncleaved than after cleavage of the CM in the presence of a cleaving agent capable of cleaving the CM. The disclosure further provides libraries of candidate ABPs, methods of screening to identify such ABPs, and methods of use. The disclosure further provides ABPs having TBMs that bind VEGF, CTLA-4, or VCAM, ABPs having a first TBM that binds VEGF and a second TBM that binds FGF, as well as compositions and methods of use. | 12-10-2009 |
20090311750 | METHODS OF CONVERTING FAB SEQUENCES INTO SINGLE CHAIN ANTIBODY SEQUENCES - In various embodiments, the present invention provides methods of converting a Fab molecule to a scFv molecule. The methods include amplifying the polynucleotide sequence of the variable light and variable heavy regions of the Fab molecule from the framework 1 to framework 4 sequences; adding one or more restriction endonuclease sites to the amino or carboxyl terminal of the amplified variable region sequence by PCR or ligation; adding one or more linker sequences to the amino or carboxyl terminal of the amplified variable region sequence by PCR or ligation. Additionally, in various embodiments the variable light chain sequence is either amino terminal or carboxyl terminal to the variable heavy chain sequence. | 12-17-2009 |
20100075377 | TETRAMERIZING POLYPEPTIDES AND METHODS OF USE - The present invention relates to a method of preparing a tetrameric protein comprising culturing a host cell transformed or transfected with an expression vector encoding a fusion protein comprising a vasodialator-stimulated phosphoprotein (VASP) domain and a heterologous protein. In one embodiment, the heterologous protein is a membrane protein, the portion of the heterologous protein that included in the fusion protein is the extracellular domain of that protein, and the resulting fusion protein is soluble. The method can be used to produced homo- and hetero-tetrameric proteins. The present invention also encompasses DNA molecules, expression vectors, and host cells used in the present method and fusion proteins produced by the present method. | 03-25-2010 |
20100189651 | MODIFIED ANTIBODY COMPOSITIONS, METHODS OF MAKING AND USING THEREOF - The present disclosure provides modified antibodies which contain an antibody or antibody fragment (AB) modified with a masking moiety (MM). Such modified antibodies can be further coupled to a cleavable moiety (CM), resulting in activatable antibodies (AAs), wherein the CM is capable of being cleaved, reduced, photolysed, or otherwise modified. AAs can exhibit an activatable conformation such that the AB is more accessible to a target after, for example, removal of the MM by cleavage, reduction, or photolysis of the CM in the presence of an agent capable of cleaving, reducing, or photolysing the CM. The disclosure further provides methods of making and using such modified antibodies and activatable antibodies. | 07-29-2010 |
20100221212 | PROPROTEINS AND METHODS OF USE THEREOF - The present disclosure provides for proprotein and activatable proprotein compositions. A proprotein contains a functional protein (i.e. a full length protein or functional fragment thereof) which is coupled to a peptide mask that inhibits the binding of the functional protein to its target or binding partner. An activatable proprotein contains a functional protein coupled to a peptide mask, and further coupled to an activatable linker, wherein in an non-activated state, the peptide mask inhibits binding of the functional protein to its target or binding partner and in an activated state the peptide mask does not inhibit binding of the functional protein to its target or binding partner. Proproteins can provide for reduced toxicity and adverse side effects that could otherwise result from binding of a functional protein at non-treatment sites if it were not inhibited from binding its binding partner. Proproteins can further provide improved biodistribution characteristics. Proproteins containing a peptide mask can display a longer in vivo or serum half-life than the corresponding functional protein not containing a peptide mask. The disclosure further provides methods of screening for, making, and using these proproteins. | 09-02-2010 |
20120149061 | Modified Antibody Compositions, Methods of Making and Using Thereof - The present disclosure provides modified antibodies which contain an antibody or antibody fragment (AB) modified with a masking moiety (MM). Such modified antibodies can be further coupled to a cleavable moiety (CM), resulting in activatable antibodies (AAs), wherein the CM is capable of being cleaved, reduced, photolysed, or otherwise modified. AAs can exhibit an activatable conformation such that the AB is more accessible to a target after, for example, removal of the MM by cleavage, reduction, or photolysis of the CM in the presence of an agent capable of cleaving, reducing, or photolysing the CM. The disclosure further provides methods of making and using such modified antibodies and activatable antibodies. | 06-14-2012 |
20120207756 | Modified Antibody Compositions, Methods of Making and Using Thereof - The present disclosure provides modified antibodies which contain an antibody or antibody fragment (AB) modified with a masking moiety (MM). Such modified antibodies can be further coupled to a cleavable moiety (CM), resulting in activatable antibodies (AAs), wherein the CM is capable of being cleaved, reduced, photolysed, or otherwise modified. AAs can exhibit an activatable conformation such that the AB is more accessible to a target after, for example, removal of the MM by cleavage, reduction, or photolysis of the CM in the presence of an agent capable of cleaving, reducing, or photolysing the CM. The disclosure further provides methods of making and using such modified antibodies and activatable antibodies. | 08-16-2012 |
20120237512 | Activatable Binding Polypeptides and Methods of Identification and Use Thereof - Activatable binding polypeptides (ABPs), which contain a target binding moiety (TBM), a masking moiety (MM), and a cleavable moiety (CM) are provided. Activatable antibody compositions, which contain a TBM containing an antigen binding domain (ABD), a MM and a CM are provided. Furthermore, ABPs which contain a first TBM, a second TBM and a CM are provided. The ABPs exhibit an “activatable” conformation such that at least one of the TBMs is less accessible to target when uncleaved than after cleavage of the CM in the presence of a cleaving agent capable of cleaving the CM. Further provided are libraries of candidate ABPs, methods of screening to identify such ABPs, and methods of use. Further provided are ABPs having TBMs that bind VEGF, CTLA-4, or VCAM, ABPs having a first TBM that binds VEGF and a second TBM that binds FGF, as well as compositions and methods of use. | 09-20-2012 |
20120237977 | Activatable Binding Polypeptides and Methods of Identification and Use Thereof - Activatable binding polypeptides (ABPs), which contain a target binding moiety (TBM), a masking moiety (MM), and a cleavable moiety (CM) are provided. Activatable antibody compositions, which contain a TBM containing an antigen binding domain (ABD), a MM and a CM are provided. Furthermore, ABPs which contain a first TBM, a second TBM and a CM are provided. The ABPs exhibit an “activatable” conformation such that at least one of the TBMs is less accessible to target when uncleaved than after cleavage of the CM in the presence of a cleaving agent capable of cleaving the CM. Further provided are libraries of candidate ABPs, methods of screening to identify such ABPs, and methods of use. Further provided are ABPs having TBMs that bind VEGF, CTLA-4, or VCAM, ABPs having a first TBM that binds VEGF and a second TBM that binds FGF, as well as compositions and methods of use. | 09-20-2012 |
20120244154 | Activatable Binding Polypeptides and Methods of Identification and Use Thereof - Activatable binding polypeptides (ABPs), which contain a target binding moiety (TBM), a masking moiety (MM), and a cleavable moiety (CM) are provided. Activatable antibody compositions, which contain a TBM containing an antigen binding domain (ABD), a MM and a CM are provided. Furthermore, ABPs which contain a first TBM, a second TBM and a CM are provided. The ABPs exhibit an “activatable” conformation such that at least one of the TBMs is less accessible to target when uncleaved than after cleavage of the CM in the presence of a cleaving agent capable of cleaving the CM. Further provided are libraries of candidate ABPs, methods of screening to identify such ABPs, and methods of use. Further provided are ABPs having TBMs that bind VEGF, CTLA-4, or VCAM, ABPs having a first TBM that binds VEGF and a second TBM that binds FGF, as well as compositions and methods of use. | 09-27-2012 |
20130101555 | Proproteins and Methods of Use Thereof - The present disclosure provides for proprotein and activatable proprotein compositions. A proprotein contains a functional protein (i.e. a full length protein or functional fragment thereof) which is coupled to a peptide mask that inhibits the binding of the functional protein to its target or binding partner. An activatable proprotein contains a functional protein coupled to a peptide mask, and further coupled to an activatable linker, wherein in an non-activated state, the peptide mask inhibits binding of the functional protein to its target or binding partner and in an activated state the peptide mask does not inhibit binding of the functional protein to its target or binding partner. Proproteins can provide for reduced toxicity and adverse side effects that could otherwise result from binding of a functional protein at non-treatment sites if it were not inhibited from binding its binding partner. Proproteins can further provide improved biodistribution characteristics. Proproteins containing a peptide mask can display a longer in vivo or serum half-life than the corresponding functional protein not containing a peptide mask. The disclosure further provides methods of screening for, making, and using these proproteins. | 04-25-2013 |
20130309230 | Modified Antibody Compositions, Methods of Making and Using Thereof - The present disclosure provides modified antibodies which contain an antibody or antibody fragment (AB) modified with a masking moiety (MM). Such modified antibodies can be further coupled to a cleavable moiety (CM), resulting in activatable antibodies (AAs), wherein the CM is capable of being cleaved, reduced, photolysed, or otherwise modified. AAs can exhibit an activatable conformation such that the AB is more accessible to a target after, for example, removal of the MM by cleavage, reduction, or photolysis of the CM in the presence of an agent capable of cleaving, reducing, or photolysing the CM. The disclosure further provides methods of making and using such modified antibodies and activatable antibodies. | 11-21-2013 |
20140024810 | Modified Antibody Compositions, Methods of Making and Using Thereof - The present disclosure provides modified antibodies which contain an antibody or antibody fragment (AB) modified with a masking moiety (MM). Such modified antibodies can be further coupled to a cleavable moiety (CM), resulting in activatable antibodies (AAs), wherein the CM is capable of being cleaved, reduced, photolysed, or otherwise modified. AAs can exhibit an activatable conformation such that the AB is more accessible to a target after, for example, removal of the MM by cleavage, reduction, or photolysis of the CM in the presence of an agent capable of cleaving, reducing, or photolysing the CM. The disclosure further provides methods of making and using such modified antibodies and activatable antibodies. | 01-23-2014 |
20140045195 | Activatable Binding Polypeptides and Methods of Identification and Use Thereof - Activatable binding polypeptides (ABPs), which contain a target binding moiety (TBM), a masking moiety (MM), and a cleavable moiety (CM) are provided. Activatable antibody compositions, which contain a TBM containing an antigen binding domain (ABD), a MM and a CM are provided. Furthermore, ABPs which contain a first TBM, a second TBM and a CM are provided. The ABPs exhibit an “activatable” conformation such that at least one of the TBMs is less accessible to target when uncleaved than after cleavage of the CM in the presence of a cleaving agent capable of cleaving the CM. Further provided are libraries of candidate ABPs, methods of screening to identify such ABPs, and methods of use. Further provided are ABPs having TBMs that bind VEGF, CTLA-4, or VCAM, ABPs having a first TBM that binds VEGF and a second TBM that binds FGF, as well as compositions and methods of use. | 02-13-2014 |
Patent application number | Description | Published |
20130315906 | Activatable Antibodies That Bind Epidermal Growth Factor Receptor And Methods Of Use Thereof - The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these anti-EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications. | 11-28-2013 |
20140010810 | Anti-Jagged 1/Jagged 2 Cross-Reactive Antibodies, Activatable Anti-Jagged Antibodies And Methods Of Use Thereof - This invention relates generally to the generation of antibodies, e.g., monoclonal antibodies including fully human monoclonal antibodies, that recognize Jagged 1 and/or Jagged 2, to antibodies, e.g., monoclonal antibodies including fully human antibodies that recognize Jagged 1 and/or Jagged 2, and nucleic acid molecules that encode antibodies, e.g., nucleic acid molecules that encode monoclonal antibodies including fully human cross-reactive antibodies that recognize both Jagged 1 and Jagged 2, and to methods of making the anti-Jagged antibodies and methods of using the anti-Jagged antibodies as therapeutics, prophylactics, and diagnostics. The invention also relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically bind to Jagged 1 and Jagged 2, and to methods of making and using these activatable anti-Jagged antibodies in a variety of therapeutic, diagnostic and prophylactic indications. | 01-09-2014 |
20140235467 | Protease-Resistant Systems for Polypeptide Display and Methods of Making and Using Thereof - The present invention generally relates to bacterial polypeptide display systems, libraries using these bacterial display systems, and methods of making and using these systems, including methods for improved display of polypeptides on the extracellular surface of bacteria using circularly permuted transmembrane bacterial polypeptides that have been modified to increase resistance to protease degradation and to enhance polypeptide display characteristics. | 08-21-2014 |
20140363430 | Activatable Antibodies that Bind Interleukin-6 Receptor and Methods of Use Thereof - The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to interleukin-6 receptor (IL-6R), and to methods of making and using these anti-IL-6R activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications. | 12-11-2014 |
Patent application number | Description | Published |
20110014673 | Systems and Methods for Effecting a Physical Change in a Biological Sample - The present invention relates generally to systems and methods for processing a biological sample that result in a physical change, such as reacting two molecules together to form a reaction product or for use in lysing viruses or biological cells for analysis using biological assay systems. As such, the present invention relates both to breaking apart biological species such as viruses and cells, as well as the formation of reactants from one or more reactive species. The sample has a volume in the range from about 1 microliter to 10 milliliters. The sample is processed by applying pressure, and either sonic energy or thermal energy to the sample, wherein the pressure achieved is usually at least 24 atmospheres, and the temperature of the sample is usually raised to at least 50° C. | 01-20-2011 |
20110294205 | AUTOMATED CELLULAR MATERIAL PREPARATION - Provided are cartridges and systems for effecting automated extraction, isolation, and purification of cellular components—such as nucleic acids—from a cellular sample in assay-ready form. Also provided are related methods of effecting such sample processing. | 12-01-2011 |
20120128548 | POLYMER MICROFLUIDIC BIOCHIP FABRICATION - Provided are microfluidic devices and methods for fabricating and bonding such devices. Also provided are kits for analyzing analyte-containing samples and for lysing cells. | 05-24-2012 |
20130295602 | METHODS, SYSTEMS AND DEVICES FOR MULTIPLE SINGLE-CELL CAPTURING AND PROCESSING USING MICROFLUIDICS - Methods, systems, and devices are described for multiple single-cell capturing and processing utilizing microfluidics. Tools and techniques are provided for capturing, partitioning, and/or manipulating individual cells from a larger population of cells along with generating genetic information and/or reactions related to each individual cell. Different capture configurations may be utilized to capture individual cells and then processing each individual cell in a multi-chamber reaction configuration. Some embodiments may provide for specific target amplification, whole genome amplification, whole transcriptome amplification, real-time PCR preparation, copy number variation, preamplification, mRNA sequencing, and/or haplotyping of the multiple individual cells that have been partitioned from the larger population of cells. Some embodiments may provide for other applications. Some embodiments may be configured for imaging the individual cells or associated reaction products as part of the processing. Reaction products may be harvested and/or further analyzed in some cases. | 11-07-2013 |
20130296196 | METHODS, SYSTEMS AND DEVICES FOR MULTIPLE SINGLE-CELL CAPTURING AND PROCESSING USING MICROFLUIDICS - Methods, systems, and devices are described for multiple single-cell capturing and processing utilizing microfluidics. Tools and techniques are provided for capturing, partitioning, and/or manipulating individual cells from a larger population of cells along with generating genetic information and/or reactions related to each individual cell. Different capture configurations may be utilized to capture individual cells and then processing each individual cell in a multi-chamber reaction configuration. Some embodiments may provide for specific target amplification, whole genome amplification, whole transcriptome amplification, real-time PCR preparation, copy number variation, preamplification, mRNA sequencing, and/or haplotyping of the multiple individual cells that have been partitioned from the larger population of cells. Some embodiments may provide for other applications. Some embodiments may be configured for imaging the individual cells or associated reaction products as part of the processing. Reaction products may be harvested and/or further analyzed in some cases. | 11-07-2013 |
20130302807 | METHODS, SYSTEMS, AND DEVICES FOR MULTIPLE SINGLE-CELL CAPTURING AND PROCESSING USING MICROFLUIDICS - Methods, systems, and devices are described for multiple single-cell capturing and processing utilizing microfluidics. Tools and techniques are provided for capturing, partitioning, and/or manipulating individual cells from a larger population of cells along with generating genetic information and/or reactions related to each individual cell. Different capture configurations may be utilized to capture individual cells and then processing each individual cell in a multi-chamber reaction configuration. Some embodiments may provide for specific target amplification, whole genome amplification, whole transcriptome amplification, real-time PCR preparation, copy number variation, preamplification, mRNA sequencing, and/or haplotyping of the multiple individual cells that have been partitioned from the larger population of cells. Some embodiments may provide for other applications. Some embodiments may be configured for imaging the individual cells or associated reaction products as part of the processing. Reaction products may be harvested and/or further analyzed in some cases. | 11-14-2013 |
20130302883 | METHODS, SYSTEMS AND DEVICES FOR MULTIPLE SINGLE-CELL CAPTURING AND PROCESSING USING MICROFLUIDICS - Methods, systems, and devices are described for multiple single-cell capturing and processing utilizing microfluidics. Tools and techniques are provided for capturing, partitioning, and/or manipulating individual cells from a larger population of cells along with generating genetic information and/or reactions related to each individual cell. Different capture configurations may be utilized to capture individual cells and then processing each individual cell in a multi-chamber reaction configuration. Some embodiments may provide for specific target amplification, whole genome amplification, whole transcriptome amplification, real-time PCR preparation, copy number variation, preamplification, mRNA sequencing, and/or haplotyping of the multiple individual cells that have been partitioned from the larger population of cells. Some embodiments may provide for other applications. Some embodiments may be configured for imaging the individual cells or associated reaction products as part of the processing. Reaction products may be harvested and/or further analyzed in some cases. | 11-14-2013 |
20130302884 | METHODS, SYSTEMS AND DEVICES FOR MULTIPLE SINGLE-CELL CAPTURING AND PROCESSING USING MICROFLUIDICS - Methods, systems, and devices are described for multiple single-cell capturing and processing utilizing microfluidics. Tools and techniques are provided for capturing, partitioning, and/or manipulating individual cells from a larger population of cells along with generating genetic information and/or reactions related to each individual cell. Different capture configurations may be utilized to capture individual cells and then processing each individual cell in a multi-chamber reaction configuration. Some embodiments may provide for specific target amplification, whole genome amplification, whole transcriptome amplification, real-time PCR preparation, copy number variation, preamplification, mRNA sequencing, and/or haplotyping of the multiple individual cells that have been partitioned from the larger population of cells. Some embodiments may provide for other applications. Some embodiments may be configured for imaging the individual cells or associated reaction products as part of the processing. Reaction products may be harvested and/or further analyzed in some cases. | 11-14-2013 |
Patent application number | Description | Published |
20080274436 | Optically regulated dental light unit - A dental system includes a light source, a power supply that adjusts a quantity of light produced by the light source, a measuring device that measures a quantity of light received from the light source, an input, through which user data, including a desired quantity of light, can be entered, and a controller which, together with the measuring device, forms at least part of a feedback loop. The controller receives the user data and communicates with the measuring device and the power supply so that the power supply adjusts a quantity of light emitted by the light source. As a result, the quantity of light received from the light source becomes substantially equal to the desired quantity of light. | 11-06-2008 |
20090046476 | Dental Light Guide - The present invention is a device that attaches to a light source to transmit and distribute light energy to the surface or internal chamber of a tooth for the purpose of photo-initiation of light curing resins and dental tooth whitening. More particularly, the invention may be used with a single or multiple Light Emitting Diode(s) to more efficiently collect and transmit the light energy emitted by the LED(s) resulting in increased total energy, uniform illumination, and collimation of the light energy delivered to the tooth. | 02-19-2009 |
20090052184 | Multi-Purpose Light Source - The present invention is a multi-purpose light source of a unique design and specialized attachments which are also independently unique that can be used for, but not limited to, Dental, Medical, Cosmetic, and Industrial applications and procedures. Specifically the spectral irradiance of the light source can be controlled in such a way as to allow it to be used for procedures currently performed by lasers, electrosurgical devices, and hand instruments while retaining the benefits of the light source for other uses such as the photo-initiation of resins, tooth whitening, fluorescence, and illumination. The present invention may be used instead of a laser either independently or in conjunction with electrosurgical devices and hand instruments. | 02-26-2009 |
20100121198 | Multi-Purpose Illumination System And Method For Tissue Examination - The present invention is a multi-purpose light source of a unique design and specialized attachments. The invention encompasses a system for the illumination and visual detection of normal and abnormal biologic tissue comprising a light source, a light transmitting device and a light viewing device wherein said device allows for the simultaneous illumination and viewing of target tissue. | 05-13-2010 |
Patent application number | Description | Published |
20100065108 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The inventive apparatus provides a one-piece coupling for interlocking the sides of PV modules together to form an array, resulting in a parallel beam support system. The inventive coupling member attaches to the frame at substantially any position along the length of the frame, and interlocks the photovoltaic module with adjacent photovoltaic modules. The inventive apparatus further includes a novel bracket member which attaches to a surface of the frame member and secures the frame member directly to a roof or other mounting surface. | 03-18-2010 |
20110000519 | PIVOT-FIT CONNECTION APPARATUS, SYSTEM, AND METHOD FOR PHOTOVOLTAIC MODULES - A system and method are disclosed for quickly and easily assembling PV modules into a PV array in a sturdy and durable manner. In examples of the present technology, the system includes various couplings having a first engaging portion adapted to engage a first PV module and a second engaging portion adapted to engage a second PV module. At least one of the engaging portions allows variable positioning of the engaged PV module along the engaging portion. | 01-06-2011 |
20110000520 | LEVELING FOOT APPARATUS, SYSTEM, AND METHOD FOR PHOTOVOLTAIC ARRAYS - A system and apparatus are disclosed for quickly and easily assembling PV modules into a PV array in a sturdy and durable manner. In examples of the present technology, the system includes a leveling foot for engaging a PV module and supporting the PV module on a support structure. The leveling foot allow adjustment of the height of engaged PV modules relative to the support structure. | 01-06-2011 |
20110000526 | PIVOT-FIT FRAME, SYSTEM AND METHOD FOR PHOTOVOLTAIC MODULES - A system and apparatus are disclosed including PV modules having a frame allowing quick and easy assembling of the PV modules into a PV array in a sturdy and durable manner. In examples of the present technology, the PV modules may have a grooved frame where the groove is provided at an angle with respect to a planar surface of the modules. Various couplings may engage within the groove to assemble the PV modules into the PV array with a pivot-fit connection. Further examples of the present technology operate with PV modules having frames without grooves, or with PV modules where the frame is omitted altogether. | 01-06-2011 |
20110000544 | DROP-IN CONNECTION APPARATUS, SYSTEM, AND METHOD FOR PHOTOVOLTAIC ARRAYS - A system and apparatus are disclosed including PV modules having a frame allowing quick and easy assembling of the PV modules into a PV array in a sturdy and durable manner. In examples of the present technology, the PV modules may have a grooved frame where the groove is provided at an angle with respect to a planar surface of the modules. Various couplings may engage within the groove to assemble the PV modules into the PV array with a pivot-fit connection. Further examples of the present technology operate with PV modules having frames without grooves, or with PV modules where the frame is omitted altogether. | 01-06-2011 |
20120125410 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 05-24-2012 |
20120255598 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 10-11-2012 |
20120260972 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 10-18-2012 |
20120279558 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 11-08-2012 |
20120298186 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 11-29-2012 |
20120298188 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 11-29-2012 |
20130133270 | Solar Panel Attachment System - A method, system and apparatus are disclosed regarding an attachment system for solar equipment, sometimes referred to as a flashing device allowing quick and easy assembling of the solar equipment into an array or other combination in a sturdy and durable manner. In examples of the present technology, a flashing device may include a flashing plate which may contain one or more raised features to further direct and control the flow of liquid over the flashing plate. The flashing device may also contain a fluid restrictor such as a seal or part of a seal usually held within an aperture of a block having a skyward facing essentially or substantially flat surface. One or more various items of solar equipment may be attached to the essentially flat surface of the block. Also disclosed are adjustable mounting feet which may be installed in connection with other solar equipment. | 05-30-2013 |
20130140416 | Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 06-06-2013 |
20130180572 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 07-18-2013 |
20130180573 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 07-18-2013 |
20130180574 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 07-18-2013 |
20130183084 | Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The coupling may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The apparatus may further provide a rotating portion and locking portion, mounting brackets for direct connection to a mounting surface, grounding teeth, and a twist-lock engagement means for interlocking and aligning PV modules in the array. | 07-18-2013 |
20140053891 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A PV module framing and coupling system which enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array and a cable management system that holds, directs, organizes, and otherwise manages cables, wires, cord, and similar components of and relating to a PV array. | 02-27-2014 |
20140182662 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - The method and apparatus for forming and mounting a photovoltaic (PV) array of this invention is disclosed and provides, without limitation, (i) a PV module framing and coupling system which enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array and (ii) an ancillary device attachment bracket, system, and method. One embodiment may provide a slidable parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement, thereby enabling the formation of a PV array with improved structural load distribution. Another embodiment may provide a photovoltaic module accessory bracket, comprising: a substantially rigid plate comprising a flexible spring tab; a first ear substantially rigidly positioned on the plate; a second ear positioned on the spring tab; wherein the spring tab flexes backward away from the plate during connection to a frame of a photovoltaic module to allow the first ear to engage the frame, and a forward force applied to the spring tab locks the second ear to the frame. | 07-03-2014 |
20140251431 | Method and Apparatus for Forming and Mounting a Photovoltaic Array - A photovoltaic (PV) module framing and coupling system enables the attachment of PV modules to a roof or other mounting surface without requiring the use of separate structural support members which attach directly to and span between multiple PV modules in a formed PV array. The inventive apparatus provides a parallel coupling for securely interlocking the outside surfaces of parallel frame members together in a side to side arrangement to form an array with improved structural load distribution. The inventive coupling member may attach to a slot in the frame at substantially any position along the length of the frame thereby enabling the interconnection of adjacent PV modules along both an x and y axis. The inventive apparatus may further provide a rotating portion and locking portion for coupling to frame attachment, mounting brackets for direct connection to a mounting surface, grounding teeth for the automatic creation of a reliable two axis grounding matrix, and a rapid twist-lock engagement means for reliably interlocking and aligning PV modules in the array. | 09-11-2014 |
20150041251 | Foothold System on Sloped Roof - Foothold system on a sloped roof includes first flashing block with hole, second flashing block with hole, moveable foothold with hook portion removably inserted into first flashing block hole and lower portion comprising a step portion extending down-roof from hook portion, the moveable foothold moveable from first flashing block to second flashing block via unhooking hook portion from first flashing block and hooking hook portion to second flashing block; flashing blocks may include mounting portion to receive mounting foot for photovoltaic array, and/or step portion sized to receive and support weight of foot of human working on sloped roof. | 02-12-2015 |
Patent application number | Description | Published |
20120152326 | Discrete Attachment Point Apparatus and System for Photovoltaic Arrays - An attachment point apparatus and system for photovoltaic arrays is disclosed. One embodiment provides a rail system for receiving a PV module, including a first rail, a second rail, a substantially rectilinear double male connector adapted for coupling an end of the first rail to an end of the second rail, and a connector adapted to attach a PV module to the first rail. Another embodiment provides a PV module including a PV laminate, a frame integral with and supporting the PV laminate, and a spanner bar adapted to solely span a width of the PV module, orthogonally connect at various locations along the frame, and attach to a support structure. A further embodiment provides a coupling device for a PV module comprising a first coupling portion adapted to rotatably engage a PV module, and a second coupling portion adapted to rotatably engage a rail. | 06-21-2012 |
20120234378 | Pivot-Fit Connection Apparatus and System for Photovoltaic Arrays - An apparatus and system for quickly and easily assembling PV modules into a PV array in a sturdy and durable manner. In some embodiments, the PV modules may have a grooved frame where the groove is angled into the frame with respect to the planar surface of the modules. Various components may engage within the angled groove to assemble the PV modules into the PV array using what may be referred to as a pivot-fit connection between the components and angled groove. Other embodiments may operate with PV modules having frames without angled grooves as by use of wraparound brackets. | 09-20-2012 |
20120266946 | Discrete Attachment Point Apparatus and System for Photovoltaic Arrays - An attachment point apparatus and system for photovoltaic arrays is disclosed. One embodiment provides a rail system for receiving a PV module, including a first rail, a second rail, a substantially rectilinear double male connector adapted for coupling an end of the first rail to an end of the second rail, and a connector adapted to attach a PV module to the first rail. Another embodiment provides a PV module including a PV laminate, a frame integral with and supporting the PV laminate, and a spanner bar adapted to solely span a width of the PV module, orthogonally connect at various locations along the frame, and attach to a support structure. A further embodiment provides a coupling device for a PV module comprising a first coupling portion adapted to rotatably engage a PV module, and a second coupling portion adapted to rotatably engage a rail. | 10-25-2012 |
20120298817 | Pivot-Fit Frame, System and Method for Photovoltaic Arrays - A system and apparatus are disclosed including PV modules having a frame allowing quick and easy assembling of the PV modules into a PV array in a sturdy and durable manner. In examples of the present technology, the PV modules may have a grooved frame where the groove is provided at an angle with respect to a planar surface of the modules. Various couplings may engage within the groove to assemble the PV modules into the PV array with a pivot-fit connection. Further examples of the present technology operate with PV modules having frames without grooves, or with PV modules where the frame is omitted altogether. | 11-29-2012 |
20120301661 | Skirt for Photovoltaic Arrays - A skirt for photovoltaic arrays provides a screen portion, a groove portion, and a separate coupling adapted to couple the skirt to the skirt of an adjacent photovoltaic array and to a photovoltaic module. Another embodiment provides a screen portion comprising an angled louver and is adapted to partially obscure an area substantially beneath a PV module in a PV array. A further embodiment provides an edge blocking skirt for a PV array comprising a screen portion adapted for mounting a bottom of the screen portion substantially close to a roof. | 11-29-2012 |
20140026946 | Discrete Attachment Point Apparatus and System for Photovoltaic Arrays - An attachment point apparatus and system for photovoltaic arrays is disclosed as well as an installed photovoltaic array using attachment apparatus. One embodiment provides a rail for receiving a PV module, including a rail member located substantially beneath at least a portion of a second photovoltaic module and having a first end located near a gap between a first and second photovoltaic modules. An embodiment also provides a second photovoltaic module which is substantially coplanar with and located between a first and third photovoltaic modules and wherein said rail member is connected to the first, second, and third photovoltaic modules and attached to a support structure by a first and second attachment brackets. A further embodiment provides a lever clip, said lever clip comprising a head portion connecting a photovoltaic module to a rail, a lever portion extending away from a head portion, and a retaining portion near an end of a lever portion wherein the lever portion acts as a lever to rotate the head portion during installation such that the head portion secures the photovoltaic module to a frame. | 01-30-2014 |
20140102997 | Photovoltaic Module Frame - The invention comprises components and a method for producing components that, without limitation, frame a photovoltaic (“PV”) module such that the frame (i) provides improved stability for the groove incorporated therein, (ii) enables a higher percentage of in-tolerance final PV module product, and (iii) enables acceptance of a wider tolerance range in raw frame extrusion than the prior art. An embodiment may include a profile with a first hollow and a second hollow, collinear to one another and separated by a diagonal component. A corner key with teeth and male portions may engage the first hollow of adjacent profiles that meet orthogonally. Once so engaged, a tool head may be applied to the corner formed by the adjacent profiles. The application of the tool head may create indentations in the profiles that engage the teeth of the corner keys within the profiles, forming a corner of a PV module frame. | 04-17-2014 |
20140130847 | PV Array Mounting for Trapezoidal Metal and Low-Slope Roofs - Components mount an array of solar panels to trapezoidal metal roofs or flat or low-slope roofs. Couplings may secure a trapezoidal metal roof mounting adapter to the peak of the trapezoidal portion of a trapezoidal metal roof, and couplings may secure additional mounting hardware to the adapter. Solar panels may connect to the rear portion of one support and the front portion of another support to achieve an angled installation to improve sun exposure. Wind diffusers may connect to solar panels to form a barrier extending from the upper-most edge of the installed solar panel downward toward the roof to impede wind. The flat and low-slope roof solution may comprise a penetration-free mechanism to install solar panels at an angle on a flat or substantially flat surface while impeding effect from wind and maintaining an electrically grounded connection between all components. | 05-15-2014 |
20140158184 | Skirt and Other Devices for Photovoltaic Arrays - A skirt and other devices for photovoltaic arrays, as well as photovoltaic arrays with a skirt(s) and/or other device(s) installed, related modules, and foothold devices and systems are herein disclosed. Various such embodiments include one or more array skirt(s), T-locks, grip(s), inside and outside corner cap(s), array trim(s), pest abatement screen(s), wire clip(s), foothold(s), groove adaptor bracket(s), magnetic skirt embodiment(s), as well as other structures and embodiments which are herein disclosed. | 06-12-2014 |
20140174511 | Photovoltaic Array Mounting Apparatus, Systems, and Methods - The invention comprises an apparatus for mounting a photovoltaic (PV) module on a surface, comprising a support with an upper surface, a lower surface, tabs, one ore more openings, and a clip comprising an arm and a notch, where the apparatus resists wind forces and seismic forces and creates a grounding electrical bond between the PV module, support, and clip. The invention further comprises a method for installing PV modules on a surface that includes arranging supports in rows along an X axis and in columns along a Y axis on a surface such that in each row the distance between two neighboring supports does not exceed the length of the longest side of a PV module and in each column the distance between two neighboring supports does not exceed the length of the shortest side of a PV module, placing a PV module upon the supports such that each corner of the frame of the PV module rests on a support, and connecting the supports to the PV module by engaging a clip to at least a portion of the frame of the PV module and to the support. The invention further comprises an apparatus for mounting a PV module on a surface, comprising a support with an upper surface, a lower surface, tabs, one or more openings, and a clip comprising an arm and a notch, and a bracket. The invention additionally comprises a method for installing a PV module on a surface that includes arranging supports in rows along an X axis and in columns along a Y axis on a surface such that in each row the distance between two neighboring supports does not exceed the length of the longest side of a PV module and in each column the distance between two neighboring supports does not exceed the length of the shortest side of a PV module, placing a PV module upon the supports such that each corner of the frame of the PV module rests on a support, connecting the supports to the PV module by engaging a clip to at least a portion of the frame of the PV module and to the support, and securing a bracket to a support and to the surface or structure. | 06-26-2014 |
20140175244 | Connecting Components for Photovoltaic Arrays - The invention includes an apparatus for mounting a photovoltaic (PV) module onto a structure where the apparatus includes a base portion, a stud portion, and a coupling portion. The coupling portion includes a male portion that acts as a spring under load and a clip portion that penetrates the PV module frame to create a grounding bond. The apparatus includes a lower jaw, shaped to pry open a groove, and a key portion that can compress to allow for tolerances. The invention further includes a clip with one or more tabs and one or more teeth. The invention further includes a replacement roof tile which includes a support structure with a horizontal flange, a vertical component, a horizontal component, a flashing with an upper surface and a lower surface, and a tile-shaped metal surface having a curvilinear shape that reflects the shapes of adjacent tiles. | 06-26-2014 |
20140246549 | Torque Tube Mounted Photovoltaic Apparatus, System, and Method - An interlocking system for connecting photovoltaic module frames to a torque tube, including: (a) an interlock dimensioned to be positioned between the sides of two adjacent photovoltaic module frames; (b) a pair of couplings or flanges, wherein the couplings or flanges connect the interlock to both of the adjacent photovoltaic module frames; and (c) a U-lock connected to the interlock, wherein the U-lock is dimensioned to be connected to a torque tube. | 09-04-2014 |
20140326838 | Apparatus, System, and Method for Photovoltaic-Related Wire Management - A flexible wire clip dimensioned to be snapped into a side groove on a photovoltaic module frame, wherein the wire clip flexes during installation such that a catch moves away from a frame-receiving slot and slides upwardly against a side edge of a photovoltaic module frame so that a frame member of a photovoltaic module frame can be inserted into the frame-receiving slot, and wherein the wire clip returns to a substantially non-flexed position after it has been snapped into the side groove of a photovoltaic module frame. | 11-06-2014 |
Patent application number | Description | Published |
20090099813 | Time Delay Estimation - A time differential is estimated between a plurality of signals by determining a filter response of a first electrical signal with a first filter array, determining a filter response of a second electrical signal with a second filter array, and determining, based at least on the filter response of the first electrical signal and the filter response of the second electrical signal, a time differential between the first electrical signal and the second electrical signal. A first optical signal is converted into the first electrical signal and a second optical signal is converted into the second electrical signal. The filter response of the first electrical signal and the filter response of the second electrical signal are sampled and the time differential between the first electrical signal and the second electrical signal is determined based at least on the sampled filter response of the first electrical signal and the sampled filter response of the second electrical signal. | 04-16-2009 |
20090102313 | Transmission Lines Applied to Contact Free Slip Rings - A non-contacting rotary interface has a first core with a first pair of balanced transmission lines coupled to the first core and a second core moveable in relation to the first core with a second pair of balanced transmission lines coupled to the second core and configured to receive signals from the first pair of balanced transmission lines. The first pair of balanced transmission lines has a first transmit wire coupled to a first transceiver at a first end of the first transmit wire, a second transceiver coupled to the first transmit wire at a second end of the first transmit wire, a second transmit wire coupled to a third transceiver at a first end of the second transmit wire, and a fourth transceiver coupled to the second transmit wire at a second end of the second transmit wire. The balanced transmission lines may be electrical traces on a circuit board. | 04-23-2009 |
20110161031 | Time Delay Estimation - A time differential is estimated between a plurality of signals by determining a filter response of a first electrical signal with a first filter array, determining a filter response of a second electrical signal with a second filter array, and determining, based at least on the filter response of the first electrical signal and the filter response of the second electrical signal, a time differential between the first electrical signal and the second electrical signal. A first optical signal is converted into the first electrical signal and a second optical signal is converted into the second electrical signal. The filter response of the first electrical signal and the filter response of the second electrical signal are sampled and the time differential between the first electrical signal and the second electrical signal is determined based at least on the sampled filter response of the first electrical signal and the sampled filter response of the second electrical signal. | 06-30-2011 |
20110184699 | Time Delay Estimation - A time differential is estimated between a plurality of signals by determining a filter response of a first electrical signal with a first filter array, determining a filter response of a second electrical signal with a second filter array, and determining, based at least on the filter response of the first electrical signal and the filter response of the second electrical signal, a time differential between the first electrical signal and the second electrical signal. A first optical signal is converted into the first electrical signal and a second optical signal is converted into the second electrical signal. The filter response of the first electrical signal and the filter response of the second electrical signal are sampled and the time differential between the first electrical signal and the second electrical signal is determined based at least on the sampled filter response of the first electrical signal and the sampled filter response of the second electrical signal. | 07-28-2011 |
20120218061 | Transmission Lines Applied to Contact Free Slip Rings - A non-contacting rotary interface has a first core with a first pair of balanced transmission lines coupled to the first core and a second core moveable in relation to the first core with a second pair of balanced transmission lines coupled to the second core and configured to receive signals from the first pair of balanced transmission lines. The first pair of balanced transmission lines has a first transmit wire coupled to a termination point at a first end of the first transmit wire, a first transceiver coupled to the first transmit wire at a second end of the first transmit wire, a second transmit wire coupled to the termination point at a first end of the second transmit wire, and a second transceiver coupled to the second transmit wire at a second end of the second transmit wire. The balanced transmission lines may be electrical traces on a circuit board. | 08-30-2012 |
Patent application number | Description | Published |
20100100456 | CELL ONTOGENY INFORMATION SYSTEMS AND METHODS OF USING THE SAME - Aspects of the invention are drawn to cell ontogeny information systems and methods for using the same. | 04-22-2010 |
20130011918 | METHODS FOR TELOMERE LENGTH AND GENOMIC DNA QUALITY CONTROL AND ANALYSIS IN PLURIPOTENT STEM CELLS - The generation of clinical-grade cell-based therapies from human embryonic stem cells or cells reprogrammed to pluripotency from somatic cells, requires stringent quality controls to insure that the cells have long enough telomeres and resulting cellular lifespan to be clinically useful, and normal gene expression and genomic integrity so as to insure cells with a desired and reproducible phenotype and to reduce the risk of the malignant transformation of cells. Assays useful in identifying human embryonic stem cell lines and pluripotent cells resulting from the transcriptional reprogramming of somatic cells that have embryonic telomere length are described as well as quality control assays for screening genomic integrity in cells expanded and banked for therapeutic use, as well as assays to identify cells capable of abnormal immortalization, | 01-10-2013 |
20130115673 | Methods of Screening Embryonic Progenitor Cell Lines - Aspects of the present invention include methods and compositions related to the production and use of numerous clonal lineages of embryonic progenitor cell lines derived from differentiating cultures of primordial stem cells with diverse molecular markers and having been cultured for >21 doublings of clonal expansion. The robustness of these clonally-purified lines, their ability to expand for >40 passages while maintaining their pattern of gene expression, lack of tumorigenicity, and their embryonic pattern of gene expression offers novel compositions and methods for modeling numerous differentiation pathways for the first time in vitro, and for the manufacture of purified product not existing in such a purified state in nature or using other manufacturing modalities. Representative progenitor cell lines described herein are capable of development into cutaneous adipocytes, blood-brain barrier cells, neuronal cells, or smooth muscle cells each with therapeutic potential. | 05-09-2013 |
20130295581 | Methods and Compositions for the Treatment and Diagnosis of Breast Cancer - The invention provides methods, compositions and kits relating to the diagnosis, prognosis and treatment of breast cancer. | 11-07-2013 |
20140099712 | Methods and Compositions for Targeting Progenitor Cell Lines - The invention provides methods, compositions and kits for the identification and enrichment of progenitor cell lines obtained from pluripotent stem cells. | 04-10-2014 |
20140141996 | Methods and Compositions for the Treatment and Diagnosis of Cancer - Embodiments of the disclosure are directed to methods of diagnosis, prognosis and treatment of cancer. In some embodiments, the methods include targeting a marker that is expressed at abnormal levels in bladder cancer tissue in comparison to normal somatic tissue. Some embodiments are directed to methods of treating cancer comprising administering a composition including a therapeutic that affects the expression or function of a target marker. Some embodiments are directed to methods of detecting cancer comprising detecting a level of a target marker associated with the cancer, | 05-22-2014 |
20140154691 | Methods and Compositions for the Treatment and Diagnosis of Bladder Cancer - Embodiments of the disclosure are directed to methods of diagnosis, prognosis and treatment of cancer. The methods are particularly suited for bladder cancer. The methods include targeting a marker that is expressed at abnormal levels in bladder cancer tissue in comparison to normal somatic tissue. Also disclosed are methods of treating cancer comprising administering a composition including a therapeutic that affects the expression or function of a target marker. | 06-05-2014 |
20140178988 | Differentiated Progeny of Clonal Progenitor Cell Lines - Aspects of the present invention include methods and compositions related to the production and use of embryonic progenitor cell types useful in the generation of cartilage, bone, choroid plexus, tendon, lipasin-secreting adipocytes, and other differentiated cell types useful in research and therapy. | 06-26-2014 |
20140178994 | Methods and Compositions for In Vitro and In Vivo Chondrogenesis - Aspects of the present invention include methods and compositions related to the production, identification and use of embryonic progenitor cell lines that are capable of undergoing chondrogenesis. A number of exemplary chondrogenic cell lines derived from primordial stem cells are disclosed. The chondrogenic cell lines described herein are robust, can expand for >40 passages, and have site-specific purity, thus providing for compositions and methods of producing diverse cartilage types with unique molecular compositions for use in research and therapy. | 06-26-2014 |
20140206574 | Methods and Compositons for the Treatment and Diagnosis of Cancer - The invention relates to methods of detecting cancer in a sample obtained from a subject. The invention also provides kits and reagents for detecting cancer as well as therapeutics and methods of treating cancer. | 07-24-2014 |
20140221244 | Methods and Compositions for the Treatment and Diagnosis of Colorectal Cancer - The invention provides methods, compositions and kits relating to the detection, diagnosis, treatment of colorectal cancer. | 08-07-2014 |
20140234964 | Novel Methods and Formulations for Orthopedic Cell Therapy - Aspects of the present invention include methods and compositions related to the production and use of clonal lineages of embryonic progenitor cell lines derived from differentiating cultures of primordial stem cells, in particular, said methods and compositions relate to methods of differentiating cells in the presence of BMP family mambeis of growth factors and the applications of said cell lines in the treatment of degenerative orthopedic diseases such as osteoarthritis, | 08-21-2014 |
20140235486 | Methods and Compositions for the Treatment and Diagnosis of Breast Cancer - The invention provides for methods of diagnosis, prognosis and treatment of cancer including, but not limited to, breast cancer. | 08-21-2014 |
20140248700 | Method of Differentiation of Morula or Inner Cell Mass Cells and Method of Making Lineage-Defective Embryonic Stem Cells - An improved method of producing differentiated progenitor cells comprising obtaining inner cell mass cells from a blastocyst and inducing differentiation of the inner cell mass cells to produce differentiated progenitor cells. The differentiated progenitor cells may be transfected such that there is an addition, deletion or alteration of a desired gene. The differentiated progenitor cells are useful in cell therapy and as a I source of cells for the production of tissues and organs for transplantation. Also provided is a method of producing a lineage-defective human embryonic stem cell. | 09-04-2014 |
20140315743 | Methods and Compositions for the Treatment and Diagnosis of Ovarian Cancer - The invention relates to methods, compositions and kits for the diagnosis, detection, and treatment of ovarian cancer. | 10-23-2014 |
20140323342 | Methods and Compositions for the Treatment and Diagnosis of Bladder Cancer - The invention provides methods, compositions and kits for the detection and treatment of bladder cancer. | 10-30-2014 |
20140349396 | Compositions and Methods Relating to Clonal Progenitor Cells - Aspects of the present invention include methods and compositions related to the production and use of clonal lineages of embryonic progenitor cell lines derived from differentiating cultures of primordial stem cells. In particular, said methods and compositions relate to methods of differentiating cells in the presence of agents that inhibit the signaling of the TGF beta family members of growth factors and the applications of said cell lines in the treatment of diseases such as degenerative muscle disorders, cancer, and vascular disease. | 11-27-2014 |
20140357518 | Methods and Compositions for the Treatment and Diagnosis of Thyroid Cancer - The invention provides methods, compositions and kits for the detection and treatment of thyroid cancer. | 12-04-2014 |
20150018235 | Methods and Compositions for the Treatment and Diagnosis of Pancreatic Cancer - The invention provides methods, compositions and kits for the detection and treatment of pancreatic cancer. | 01-15-2015 |
Patent application number | Description | Published |
20090104697 | Method of differentiation of morula or inner cell mass cells and method of making lineage-defective embryonic stem cells - An improved method of producing differentiated progenitor cells comprising obtaining inner cell mass cells from a blastocyst and inducing differentiation of the inner cell mass cells to produce differentiated progenitor cells. The differentiated progenitor cells may be transfected such that there is an addition, deletion or alteration of a desired gene. The differentiated progenitor cells are useful in cell therapy and as a I source of cells for the production of tissues and organs for transplantation. Also provided is a method of producing a lineage-defective human embryonic stem cell. | 04-23-2009 |
20090215640 | METHODS FOR IDENTIFYING LIGANDS FOR STEM CELLS AND CELLS DERIVED THEREFROM - The present invention provides methods for the identification of novel ligands to pluripotent stem cells such as human embryonic stem cells, human embryo-derived cells, and from cells differentiated from such cells, and the use of such ligands in identifying differentiation conditions, purifying cells, and for eliminating such cells from mixtures of varied cell types. The invention also provides methods for the identification of target progenitor cells and cells identified thereby. | 08-27-2009 |
20090253588 | Screening assays for identifying differentiation-inducing agents and production of differentiated cells for cell therapy - The invention relates to assays for screening growth factors, adhesion molecules, immunostimulatory molecules, extracellular matrix components and other materials, alone or in combination, simultaneously or temporally, for the ability to induce directed differentiation of pluripotent and multipotent stem cells. | 10-08-2009 |
20090271335 | Totipotent, Nearly Totipotent or Pluripotent Mammalian Cells Homozygous or Hemizygous for One or More Histocompatibility Antigent Genes - The present invention relates to totipotent, nearly totipotent and pluripotent stem cells that are hemizygous or homozygous for MHC antigens and methods of making and using them. These cells are useful for reduced immunogenicity during transplantation and cell therapy. The cells of the present invention may be assembled into a bank with reduced complexity in the MHC genes. | 10-29-2009 |
20100167404 | Methods of Reprogramming Animal Somatic Cells - This invention generally relates to methods to obtain mammalian cells and tissues with patterns of gene expression similar to that of a developing mammalian embryo or fetus, and the use of such cells and tissues in the treatment of human disease and age-related conditions. More particularly, the invention relates to methods for identifying, expanding in culture, and formulating mammalian pluripotent stem cells and differentiated cells that differ from cells in the adult human in their pattern of gene expression, and therefore offer unique characteristics that provide novel therapeutic strategies in the treatment of degenerative disease. | 07-01-2010 |
20100184033 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY - Aspects of the present invention relate to methods to differentiate pluripotent primordial stem cells, such as human embryonic stem (“hES”) cells, human embryonic germ (“hEG”) cells, human embryo-derived (“hED”) cells and human embryonal carcinoma (“hEC”) cells, to obtain subpopulations of cells from heterogeneous mixtures of cells, wherein the subpopulation of cells possess reduced differentiation potential compared to the original pluripotent stem cells and where the subpopulation is capable of being propagated 20 or more population doublings. This invention also provides novel compositions of such subpopulations of cells and methods to propagate and differentiate said cells. | 07-22-2010 |
20110143441 | Methods of Reprogramming Animal Somatic Cells - This invention generally relates to methods to obtain mammalian cells and tissues with patterns of gene expression similar to that of a developing mammalian embryo or fetus, and the use of such cells and tissues in the treatment of human disease and age-related conditions. More particularly, the invention relates to methods for identifying, expanding in culture, and formulating mammalian pluripotent stem cells and differentiated cells that differ from cells in the adult human in their pattern of gene expression, and therefore offer unique characteristics that provide novel therapeutic strategies in the treatment of degenerative disease. | 06-16-2011 |
20110171185 | Genetically intact induced pluripotent cells or transdifferentiated cells and methods for the production thereof - The present disclosure relates to methods for dedifferentiating and transdifferentiating recipient cells, preferably human somatic cells. These methods minimize the risk of undesired genome sequence alteration. These methods employ reprogramming factors, which may be used alone or in certain combinations with one another. These methods have application especially in the context of cell-based therapies, establishment of cell lines, and the production of genetically modified cells. | 07-14-2011 |
20110256622 | Novel Culture Systems for Ex Vivo Development - The present invention provides methods for the culture of animal pluripotent stem cells and their differentiated progeny cells, tissues, and organs, and nonhuman animal embryos and fetuses. | 10-20-2011 |
20110286978 | Genetically Intact Induced Pluripotent Cells Or Transdifferentiated Cells And Methods For The Production Thereof - The present disclosure relates to methods for dedifferentiating and transdifferentiating recipient cells, preferably human somatic cells. These methods minimize the risk of undesired genome sequence alteration. These methods employ reprogramming factors, which may be used alone or in certain combinations with one another. These methods have application especially in the context of cell-based therapies, establishment of cell lines, and the production of genetically modified cells. | 11-24-2011 |
20120129262 | Methods of Modifying Transcriptional Regulatory Networks in Stem Cells - The vast differentiation potential of human embryonic and induced pluripotent stem cells, including their potential to cascade through all of the somatic cell lineages and to display the complete transcriptional regulatory network of human biology, has generated interest in deriving scalable, purified, and identified cell types and methods of discovering the precise structure of the human regulatory network. However, the innate capacity of pluripotent cells to display all these lineages is not necessarily reflected during their culture in vitro. The clonal isolation and propagation of progenitors greatly facilitates the generation of highly purified and identified formulations for research and therapeutic purposes. Nevertheless, other cell types have yet to be isolated and propagated from normal cells and methods of isolating said novel cell types as well as methods for introducing perturbations into the transcriptional regulatory network in order to construct a computer model of the entire human transcriptional regulatory network would greatly benefit basic research as well as manufacturing technology for cell-based therapies. | 05-24-2012 |
20120171171 | Methods and Compositions for In Vitro and In Vivo Chondrogenesis - Aspects of the present invention include methods and compositions related to the production, identification and use of embryonic progenitor cell lines that are capable of undergoing chondrogenesis. A number of exemplary chondrogenic cell lines derived from primordial stem cells are disclosed. The chondrogenic cell lines described herein are robust, can expand for >40 passages, and have site-specific purity, thus providing for compositions and methods of producing diverse cartilage types with unique molecular compositions for use in research and therapy. | 07-05-2012 |
20130053278 | TOTIPOTENT, NEARLY TOTIPOTENT OR PLURIPOTENT MAMMALIAN CELLS HOMOZYGOUS OR HEMIZYGOUS FOR ONE OR MORE HISTOCOMPATIBILITY ANTIGENS GENES - The present invention relates to totipotent, nearly totipotent and pluripotent stem cells that are hemizygous or homozygous for MHC antigens and methods of making and using them. These cells are useful for reduced immunogenicity during transplantation and cell therapy. The cells of the present invention may be assembled into a bank with reduced complexity in the MHC genes. | 02-28-2013 |
20140057348 | Novel Culture System for Ex Vivo Development - The present invention provides methods for the culture of animal pluripotent stem cells and their differentiated progeny cells, tissues, and organs, and nonhuman animal embryos and fetuses. | 02-27-2014 |
Patent application number | Description | Published |
20110066260 | SYSTEM AND METHOD FOR DYNAMICALLY ADJUSTING PATIENT THERAPY - A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and/or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and/or halt the delivery of medication to the patient until the alert is resolved. | 03-17-2011 |
20120016215 | SYSTEM AND METHOD FOR DYNAMICALLY ADJUSTING PATIENT THERAPY - A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and/or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and/or halt the delivery of medication to the patient until the alert is resolved. | 01-19-2012 |
20130096444 | SYSTEM AND METHOD FOR DYNAMICALLY ADJUSTING PATIENT THERAPY - A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and/or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and/or halt the delivery of medication to the patient until the alert is resolved. | 04-18-2013 |
20140100868 | SYSTEM AND METHOD FOR DYNAMICALLY ADJUSTING PATIENT THERAPY - A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values at vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and/or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and/or halt the delivery of medication to the patient until the alert is resolved. | 04-10-2014 |
20140297313 | SYSTEM AND METHOD FOR DYNAMICALLY ADJUSTING PATIENT THERAPY - A system and method of managing therapy provided to patients in an institution. The system monitors all aspects of the medication delivery to a patient, as well as other information related to the patient, such as values of vital signs, laboratory results and patient factors such as history, diagnosis, allergies and the like. The system includes one or more databases of information, including institutionally developed rules, guidelines and protocol representing the best medical practices of the institution. The system provides alerts and/or recommendations based on the application of the rules to the information being monitored, and alerts care givers accordingly, providing for dynamic adjustment of the patient's therapy. The system also monitors the status of the alerts, and if no action is taken in a selected period of time, may escalate the priority of the alert and/or halt the delivery of medication to the patient until the alert is resolved. | 10-02-2014 |
Patent application number | Description | Published |
20110308833 | PHOTOVOLTAIC STRING SUB-COMBINER - An improved method of collecting DC power in solar photovoltaic systems is disclosed where series string overcurrent protection is provided at distributed series string terminus locations and a tap connection is made to higher current conductors carrying the combined currents of a number of series strings. A number of related string combiner methods and embodiments are disclosed. | 12-22-2011 |
20110309690 | CENTRALIZED ISLANDING PROTECTION FOR DISTRIBUTED RENEWABLE ENERGY GENERATORS - A device and method is disclosed for providing anti-islanding protection for an electrical grid-tied power converter, which is autonomous to the operation of the power converter. The device can protect any number of paralleled power converters and can independently determine if an islanding condition exists. The method involves actively perturbing the electrical grid at a common point of coupling between converter and grid, observing the effect of the perturbation, comparing the perturbed and non-perturbed grid characteristics and disconnecting the converter from the grid if a run-on or islanding condition is indicated. Perturbation is accomplished switching a reactive load or loads onto the grid or by changing a transformer tap connection at the point of common coupling. | 12-22-2011 |
20120025609 | VERY HIGH EFFICIENCY UNINTERRUPTIBLE POWER SUPPLY - The invention is an electrical power conversion topology. The preferred embodiment is as a three-phase, on-line Uninterruptible Power Supply (UPS). The desired AC output voltage waveform is formed on each output line or phase of the UPS, using pulse modulation techniques and a smoothing output filter inductor. A semiconductor switching matrix is used to switch the power converter side of each output filter inductor between three voltage potentials, a positive battery potential, a negative battery potential and a third intermediate and varying AC potential synchronized with the desired output voltage. The invention potentially provides the same performance as that of a multi-level inverter topology approaching an infinite number of DC levels. | 02-02-2012 |
20120026770 | POWER CONVERTER WITH LINEAR DISTRIBUTION OF HEAT SOURCES - A power converter design is disclosed with a novel approach to thermal management which enhances the performance and significantly reduces the cost of the converter compared to prior art power converters. The invention minimizes the heating of one power component by another within the power converter and therefore enables the power converter to work at higher power levels. Essentially, the power converter uses a heatsink having a high length to width ratio, a linear array of power components thermally coupled to the heatsink parallel to the long axis of the heatsink and a heat removal system which produces the highest cross sectional thermal flux perpendicular to said long axis. In addition, a number of ancillary thermal management techniques are used to significantly enhance the value of this basic approach. A specific circuit design for the power converter is not disclosed or discussed as the invention can be applied to any number of power converter electrical topologies. What is addressed is the specific thermal management of the three primary component groups found in any power converter; semiconductor devices, magnetic components and capacitors. The invention uses specific geometries and power component arrangements as well as strategic use of advanced thermal materials. | 02-02-2012 |
20120039003 | BIPOLAR PHOTOVOLTAIC ARRAY GROUNDING APPARATUS AND METHOD - The invention is an apparatus and method for safely disconnecting a bipolar photovoltaic array from earth ground under normal static operating conditions. The invention senses the voltage to earth on all three terminals of a bipolar photovoltaic array and uses a set of operable contacts to selectively couple or uncouple the DC neutral point of the array (the center tap) to earth ground. When all three terminals of the bipolar array are within the rated voltage capability of the photovoltaic array the DC neutral point is allowed to float. | 02-16-2012 |
20120133477 | RENEWABLE ONE-TIME LOAD BREAK CONTACTOR - An electrical contactor with high DC and AC interrupt capability is disclosed. The invention is intended for applications where load break capability is only required under abnormal operating conditions. Under overload conditions, an alternate path is automatically provided through a sacrificial fuse to divert current from opening, or open and arcing, contacts such that the fuse interrupts the fault current and not the contacts. The current rating of the sacrificial fuse may be orders of magnitude less than the normal carry current of the contactor. The contactor provides a one-time load break function that is renewable by the replacement of a fuse. | 05-31-2012 |
20140034613 | PHOTOVOLTAIC SWITCHGEAR WITH SACRIFICIAL FUSE - The invention is a photovoltaic-specific, DC load-break disconnect switch intended for applications where load-break capability is only required under abnormal operating conditions or in an emergency due to the catastrophic failure or other system components. Under normal operating conditions, the load will be switched off before a DC disconnect switch is opened. Under conditions where a load-break disconnect operation is required, an alternate path is automatically provided through a sacrificial fuse to divert current from opening contacts such that the fuse interrupts the current and not the contacts, thereby providing a substantially arcless load break. The current rating of the sacrificial fuse may be orders of magnitude less than the normal carry current. Equipment based on this invention will provide a one-time load break function that is renewable by the replacement of a fuse. The invention leverages the superior, cost-effective fault clearing capability of fuses in DC applications. | 02-06-2014 |
20140041709 | GEO-COOLED PHOTOVOLTAIC POWER CONVERTER - The invention is a liquid cooled photovoltaic power converter with a liquid-to-earth heat exchanger. With the invention, removal of heat from primary power converter heat sources is accomplished without cooling fans or ambient air exchange in order to eliminate associated particulate contamination and maintenance issues. | 02-13-2014 |
20140376293 | PARALLELABLE THREE-PHASE PHOTOVOLTAIC POWER CONVERTER - The invention is a bipolar solar photovoltaic to three-phase AC power converter with a novel non-isolated power conversion topology which allows multiple power converter outputs to be directly paralleled without the need for synchronized switching or galvanic isolation. The invention directly supports a new approach to solar photovoltaic system design wherein a large number of distributed lower power converters are used in lieu of one large central inverter. | 12-25-2014 |
20150016162 | PHOTOVOLTAIC INVERTER WITH SWINGING LINE FILTER INDUCTORS - The invention is a high efficiency single-phase or poly-phase DC-to-AC power converter apparatus and power conversion method which includes a line filter inductor or line filter inductors to integrate or filter pulse modulated waveforms into substantially sinusoidal waveforms wherein (i) the line filter inductor or inductors have inductance values that swing substantially from zero current to peak rated current and (ii) a pulse width modulation technique is used that varies both pulse width modulation duty cycles and periods as a function of the predicted instantaneous line filter inductance and the predicted di/dt across the line filter inductor or inductors in order to minimize power converter switching losses while maintaining AC power quality. With the invention, substantial CEC power conversion efficiency enhancements should be achievable and with an overall reduction in power converter parts cost. | 01-15-2015 |
20150016168 | HIGHLY STABLE MAXIMUM POWER POINT TRACKING FOR BIPOLAR PHOTOVOLTAIC INVERTERS - The invention is a method of tracking the overall maximum power point of a grounded bipolar photovoltaic array by tracking and regulating the voltage of the weaker of the two monopolar subarrays at any instant in time. The transfer between subarrays being tracked for the maximum power point is seamless when the voltage of one subarray becomes lower than the other. This tracking method insures stable operation and maximum power transfer under all balanced and unbalanced PV array conditions. This tracking algorithm would typically be part of a larger digital power converter control system. | 01-15-2015 |
Patent application number | Description | Published |
20120112220 | LED-Based Light Source Utilizing Asymmetric Conductors - A light source includes LED dies that are flip-chip mounted on a flexible plastic substrate. The LED dies are attached to the substrate using an asymmetric conductor material with deformable conducting particles sandwiched between surface mount contacts on the LED dies and traces on the substrate. A diffusively reflective material containing light scattering particles is used instead of expensive reflective cups to reflect light upwards that is emitted sideways from the LED dies. The diffusively reflective material is dispensed over the top surface of the substrate and contacts the side surfaces of the dies. The light scattering particles are spheres of titanium dioxide suspended in silicone. The light source is manufactured in a reel-to-reel process in which the asymmetric conductor material and the diffusively reflective material are cured simultaneously. A silicone layer of molded lenses including phosphor particles is also added over the mounted LED dies in the reel-to-reel process. | 05-10-2012 |
20120175643 | Packaging Photon Building Blocks Having Only Top Side Connections in an Interconnect Structure - Standardized photon building blocks are used to make both discrete light emitters as well as array products. Each photon building block has one or more LED chips mounted on a substrate. No electrical conductors pass between the top and bottom surfaces of the substrate. The photon building blocks are supported by an interconnect structure that is attached to a heat sink. Landing pads on the top surface of the substrate of each photon building block are attached to contact pads disposed on the underside of a lip of the interconnect structure. In a solder reflow process, the photon building blocks self-align within the interconnect structure. Conductors on the interconnect structure are electrically coupled to the LED dice in the photon building blocks through the contact pads and landing pads. The bottom surface of the interconnect structure is coplanar with the bottom surfaces of the substrates of the photon building blocks. | 07-12-2012 |
20120187430 | Packaging Photon Building Blocks Having Only Top Side Connections in a Molded Interconnect Structure - Standardized photon building blocks are packaged in molded interconnect structures to form a variety of LED array products. No electrical conductors pass between the top and bottom surfaces of the substrate upon which LED dies are mounted. Microdots of highly reflective material are jetted onto the top surface. Landing pads on the top surface of the substrate are attached to contact pads disposed on the underside of a lip of the interconnect structure. In a solder reflow process, the photon building blocks self-align within the interconnect structure. Conductors in the interconnect structure are electrically coupled to the LED dies in the photon building blocks through the contact pads and landing pads. Compression molding is used to form lenses over the LED dies and leaves a flash layer of silicone covering the landing pads. The flash layer laterally above the landing pads is removed by blasting particles at the flash layer. | 07-26-2012 |
20130105837 | JETTING A HIGHLY REFLECTIVE LAYER ONTO AN LED ASSEMBLY | 05-02-2013 |
20130113016 | PACKAGING PHOTON BUILDING BLOCKS WITH TOP SIDE CONNECTIONS AND INTERCONNECT STRUCTURE - Standardized photon building blocks are used to make both discrete light emitters as well as array products. Each photon building block has one or more LED chips mounted on a substrate. No electrical conductors pass between the top and bottom surfaces of the substrate. The photon building blocks are supported by an interconnect structure that is attached to a heat sink. Landing pads on the top surface of the substrate of each photon building block are attached to contact pads disposed on the underside of a lip of the interconnect structure. In a solder reflow process, the photon building blocks self-align within the interconnect structure. Conductors on the interconnect structure are electrically coupled to the LED dice in the photon building blocks through the contact pads and landing pads. The bottom surface of the interconnect structure is coplanar with the bottom surfaces of the substrates of the photon building blocks. | 05-09-2013 |
20130134459 | Micro-Bead Blasting Process for Removing a Silicone Flash Layer - Using compression molding to form lenses over LED arrays on a metal core printed circuit board leaves a flash layer of silicone covering the contact pads that are later required to connect the arrays to power. A method for removing the flash layer involves blasting particles of sodium bicarbonate at the flash layer. A nozzle is positioned within thirty millimeters of the top surface of the flash layer. The stream of air that exits from the nozzle is directed towards the top surface at an angle between five and thirty degrees away from normal to the top surface. The particles of sodium bicarbonate are added to the stream of air and then collide into the top surface of the silicone flash layer until the flash layer laterally above the contact pads is removed. The edge of silicone around the cleaned contact pad thereafter contains a trace amount of sodium bicarbonate. | 05-30-2013 |
20130292709 | LED Lens Design with More Uniform Color-Over-Angle Emission - An LED device with improved angular color performance has a silicone lens shaped as a portion of a sphere. The lens is molded over an array of LED dies disposed on the upper surface of a substrate. Phosphor particles are disbursed throughout the material used to mold the lens. The distance between farthest apart edges of the LED dies is more than half of the length that the lens extends over the surface of the substrate. The distance from the top of the lens dome to the surface of the substrate is between 57% and 73% of the radius of the sphere. Shaping the lens as the top two thirds of a hemisphere reduces the non-uniformity in the emitted color such that neither of the CIE color coordinates x or y of the color changes more than 0.004 over all emission angles relative to the surface of the substrate. | 11-07-2013 |
20130337592 | MICRO-BEAD BLASTING PROCESS FOR REMOVING A SILICONE FLASH LAYER - Using compression molding to form lenses over LED arrays on a metal core printed circuit board leaves a flash layer of silicone covering the contact pads that are later required to connect the arrays to power. A method for removing the flash layer involves blasting particles of sodium bicarbonate at the flash layer. A nozzle is positioned within thirty millimeters of the top surface of the flash layer. The stream of air that exits from the nozzle is directed towards the top surface at an angle between five and thirty degrees away from normal to the top surface. The particles of sodium bicarbonate are added to the stream of air and then collide into the top surface of the silicone flash layer until the flash layer laterally above the contact pads is removed. The edge of silicone around the cleaned contact pad thereafter contains a trace amount of sodium bicarbonate. | 12-19-2013 |
20140048832 | Micro-Bead Blasting Process for Removing a Silicone Flash Layer - Using compression molding to form lenses over LED arrays on a metal core printed circuit board leaves a flash layer of silicone covering the contact pads that are later required to connect the arrays to power. A method for removing the flash layer involves blasting particles of sodium bicarbonate at the flash layer. A nozzle is positioned within thirty millimeters of the top surface of the flash layer. The stream of air that exits from the nozzle is directed towards the top surface at an angle between five and thirty degrees away from normal to the top surface. The particles of sodium bicarbonate are added to the stream of air and then collide into the top surface of the silicone flash layer until the flash layer laterally above the contact pads is removed. The edge of silicone around the cleaned contact pad thereafter contains a trace amount of sodium bicarbonate. | 02-20-2014 |
20140131747 | Packaging Photon Building Blocks Having Only Top Side Connections In A Molded Interconnect Structure - Standardized photon building blocks are packaged in molded interconnect structures to form a variety of LED array products. No electrical conductors pass between the top and bottom surfaces of the substrate upon which LED dies are mounted. Microdots of highly reflective material are jetted onto the top surface. Landing pads on the top surface of the substrate are attached to contact pads disposed on the underside of a lip of the interconnect structure. In a solder reflow process, the photon building blocks self-align within the interconnect structure. Conductors in the interconnect structure are electrically coupled to the LED dies in the photon building blocks through the contact pads and landing pads. Compression molding is used to form lenses over the LED dies and leaves a flash layer of silicone covering the landing pads. The flash layer laterally above the landing pads is removed by blasting particles at the flash layer. | 05-15-2014 |
20150021629 | Using An LED Die To Measure Temperature Inside Silicone That Encapsulates An LED Array - An LAM/ICM assembly comprises an integrated control module (ICM) and an LED array member (LAM). The ICM includes interconnect through which power from outside the assembly is received. In a first novel aspect, active circuitry is embedded in the ICM. In one example, the circuitry monitors LED operation, controls and supplies power to the LEDs, and communicates information into and out of the assembly. In a second novel aspect, a lighting system comprises an AC-to-DC converter and a LAM/ICM assembly. The AC-to-DC converter outputs a substantially constant current or voltage. The magnitude of the current or voltage is adjusted by a signal output from the LAM/ICM. In a third novel aspect, the ICM includes a switching DC-to-DC converter. An AC-to-DC power supply supplies a roughly regulated supply voltage. The switching converter within the LAM/ICM receives the roughly regulated voltage and supplies a regulated LED drive current to its LEDs. | 01-22-2015 |
20150022088 | LED Array Member and Thermally Decoupled Integrated Control Module Assembly - A LAM/ICM assembly comprises an integrated control module (ICM) and an LED array member (LAM). In a first aspect, active circuitry is embedded in the ICM. The circuitry monitors LED operation, controls and supplies power to the LEDs, and communicates information into and out of the assembly. A thermal insulator is disposed between the ICM and a heat sink outside the lateral boundary of the LAM. In a second aspect, a lighting system comprises an AC-to-DC converter and a LAM/ICM assembly. The AC-to-DC converter outputs a substantially constant current or voltage. The magnitude of the current or voltage is adjusted by a signal output from the LAM/ICM. In a third aspect, the ICM includes a built-in switching DC-to-DC converter. An AC-to-DC power supply supplies a roughly regulated supply voltage. The switching converter within the LAM/ICM receives the roughly regulated voltage and supplies a regulated LED drive current to its LEDs. | 01-22-2015 |
20150054406 | LED Array Member and Integrated Control Module Assembly Having Active Circuitry - An LAM/ICM assembly comprises an integrated control module (ICM) and an LED array member (LAM). The ICM includes interconnect through which power from outside the assembly is received. In a first novel aspect, active circuitry is embedded in the ICM. In one example, the circuitry monitors LED operation, controls and supplies power to the LEDs, and communicates information into and out of the assembly. In a second novel aspect, a lighting system comprises an AC-to-DC converter and a LAM/ICM assembly. The AC-to-DC converter outputs a substantially constant current or voltage. The magnitude of the current or voltage is adjusted by a signal output from the LAM/ICM. In a third novel aspect, the ICM includes a switching DC-to-DC converter. An AC-to-DC power supply supplies a roughly regulated supply voltage. The switching converter within the LAM/ICM receives the roughly regulated voltage and supplies a regulated LED drive current to its LEDs. | 02-26-2015 |
Patent application number | Description | Published |
20080304207 | LOW TEMPERATURE DOUBLE-LAYER CAPACITORS - Double-layer capacitors capable of operating at extremely low temperatures (e.g., as low as −75° C.) are disclosed. Electrolyte solutions combining a base solvent (e.g., acetonitrile) and a cosolvent are employed to lower the melting point of the base electrolyte. Example cosolvents include methyl formate, ethyl acetate, methyl acetate, propionitrile, butyronitrile, and 1,3-dioxolane. An optimized concentration (e.g., 0.10 M to 0.75 M) of salt, such as tetraethylammonium tetrafluoroborate, is disolved into the electrolyte solution. In some cases (e.g., 1,3-dioxolane cosolvent) additives, such as 2% by volume triethylamine, may be included in the solvent mixture to prevent polymerization of the solution. Conventional device form factors and structural elements (e.g., porous carbon electrodes and a polyethylene separator) may be employed. | 12-11-2008 |
20110170237 | LOW TEMPERATURE DOUBLE-LAYER CAPACITORS USING ASYMMETRIC AND SPIRO-TYPE QUATERNARY AMMONIUM SALTS - Double-layer capacitors capable of operating at extremely low temperatures (e.g., as low as −80° C.) are disclosed. Electrolyte solutions combining a base solvent (e.g., acetonitrile) and a cosolvent are employed to lower the melting point of the base electrolyte. Example cosolvents include methyl formate, ethyl acetate, methyl acetate, propionitrile, butyronitrile, and 1,3-dioxolane. A quaternary ammonium salt including at least one of triethylmethylammonium tetrafluoroborate (TEMATFB) and spiro-(1,1′)-bipyrrolidium tetrafluoroborate (SBPBF | 07-14-2011 |
20120144796 | MICROFLUIDIC ELECTROSPRAY THRUSTER - An electrospray thruster and methods of manufacturing such thrusters are provided. The micro-electrospray thruster increases the thrust density of conventional electrospray thrusters by miniaturizing the individual components of the thruster thereby allowing for the increase in the number and density of the charged particle emitters. | 06-14-2012 |
20130224550 | Lithium-Based High Energy Density Flow Batteries - Systems and methods in accordance with embodiments of the invention implement a lithium-based high energy density flow battery. In one embodiment, a lithium-based high energy density flow battery includes a first anodic conductive solution that includes a lithium polyaromatic hydrocarbon complex dissolved in a solvent, a second cathodic conductive solution that includes a cathodic complex dissolved in a solvent, a solid lithium ion conductor disposed so as to separate the first solution from the second solution, such that the first conductive solution, the second conductive solution, and the solid lithium ionic conductor define a circuit, where when the circuit is closed, lithium from the lithium polyaromatic hydrocarbon complex in the first conductive solution dissociates from the lithium polyaromatic hydrocarbon complex, migrates through the solid lithium ionic conductor, and associates with the cathodic complex of the second conductive solution, and a current is generated. | 08-29-2013 |
20140021034 | SOLAR FUELS GENERATOR - The solar fuels generator includes an ionically conductive separator between a gaseous first phase and a second phase. A photoanode uses one or more components of the first phase to generate cations during operation of the solar fuels generator. A cation conduit is positioned provides a pathway along which the cations travel from the photoanode to the separator. The separator conducts the cations. A second solid cation conduit conducts the cations from the separator to a photocathode. | 01-23-2014 |
20140362495 | Systems and Methods for Implementing High-Temperature Tolerant Supercapacitors - Systems and methods in accordance with embodiments of the invention implement high-temperature tolerant supercapacitors. In one embodiment, a high-temperature tolerant super capacitor includes a first electrode that is thermally stable between at least approximately 80° C. and approximately 300° C.; a second electrode that is thermally stable between at least approximately 80° C. and approximately 300° C.; an ionically conductive separator that is thermally stable between at least approximately 80° C. and 300° C.; an electrolyte that is thermally stable between approximately at least 80° C. and approximately 300° C.; where the first electrode and second electrode are separated by the separator such that the first electrode and second electrode are not in physical contact; and where each of the first electrode and second electrode is at least partially immersed in the electrolyte solution. | 12-11-2014 |
20150056109 | SOLAR FUEL GENERATOR - The disclosure provides conductive membranes for water splitting and solar fuel generation. The membranes comprise an embedded semiconductive/photoactive material and an oxygen or hydrogen evolution catalyst. Also provided are chassis and cassettes containing the membranes for use in fuel generation. | 02-26-2015 |