Walles
Elizabeth Walles, Winston-Salem, NC US
Patent application number | Description | Published |
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20150367031 | METHODS AND COMPOSITIONS FOR INHIBITING FIBROSIS, SCARRING AND/OR FIBROTIC CONTRACTURES - Biomedical implants, regenerative scaffolds, and compositions comprise a substrate with a coating, a scaffold, and/or a carrier composition which include anisotropic nanoparticles in or on the coating, scaffold or carrier, to inhibit fibrosis, scarring, and/or fibrotic contracture, or the formation of adhesions, in a tissue contacting or administered the same. In some embodiments the nanoparticles may be electrically conductive nanoparticles such as multi wall carbon nanotubes. | 12-24-2015 |
Heike Walles, Sindelfingen DE
Patent application number | Description | Published |
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20110300530 | IN VITRO TEST SYSTEM FOR VIRAL INFECTIONS - The invention relates to a multi-layered biological in vitro tissue containing: dermis layer, containing a collagen biomatrix with fibroblasts embedded therein and epidermis layer, containing epithelial cells. It is provided that latently virally infected neuronal cells are integrated at least into the dermis layer. | 12-08-2011 |
20120058560 | Bioreactor System - Bioreactors may be used for the cultivation of cells, in particular of adherent cells, and, in particular for the cultivation and propagation of cell cultures, and utilized in methods for the cultivation of cells. A particular area of application is the use of the bioreactors in the GMP-compliant, fully automatic cultivation and propagation of cells. | 03-08-2012 |
Heike Walles, Wurzburg DE
Patent application number | Description | Published |
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20120301958 | BIOARTIFICIAL PROXIMAL TUBULE SYSTEMS AND METHODS OF USE - This application invention discloses bioartificial proximal tubule device, constructed by preparing a decellularized biological matrix, seeding the biological matrix with mammalian kidney-derived cells and optionally mammalian endothelial cells. The device may then be cultured statically or matured using bioreactor culture to allow differentiation of the kidney cells into functioning proximal tubule cells. The device is capable of carrying out proximal tubule functions. The application also describes various methods of making the proximal tubule devices. The application also further describes methods of use of bioartificial proximal tubule devices for e.g. in vitro studies of tubule cell transport, toxicity effects of various compounds or pharmaceutical compound screening. | 11-29-2012 |
20140342000 | POROUS SCAFFOLD WITH CARBON-BASED NANOPARTICLES - A biocompatible porous scaffolds, especially bone regeneration scaffolds, comprising carbon-based nanoparticles, especially diamond nanoparticles, methods for the production of such biocompatible porous scaffolds, the use of such biocompatible porous scaffolds and methods for treating bone defects by inserting such biocompatible porous scaffolds comprising carbon-based nanoparticles into the bone defect. | 11-20-2014 |