Wainer
Irving W. Wainer, Washington, DC US
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20100168245 | PREPARATION OF (R,R)-FENOTEROL AND (R,R)-OR (R,S)-FENOTEROL ANALOGUES AND THEIR USE IN TREATING CONGESTIVE HEART FAILURE - This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding β2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease. | 07-01-2010 |
20120157543 | PREPARATION OF (R,R)-FENOTEROL AND (R,R)-OR (R,S)-FENOTEROL ANALOGUES AND THEIR USE IN TREATING CONGESTIVE HEART FAILURE - This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding β2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease. | 06-21-2012 |
20130005799 | THE USE OF FENOTEROL AND FENOTEROL ANALOGUES IN THE TREATMENT OF GLIOBLASTOMAS AND ASTROCYTOMAS - This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogues for the treatment of a tumor expressing a β2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a β2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject. | 01-03-2013 |
20140296241 | THE USE OF (2R, 6R)-HYDROXYNORKETAMINE, (S)-DEHYDRONORKETAMINE AND OTHER STEREOISOMERIC DEHYDRO AND HYDROXYLATED METABOLITES OF (R,S)- KETAMINE IN THE TREATMENT OF DEPRESSION AND NEUROPATHIC PAIN - The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or hydroxylated ketamine metabolite. (2R,6R)-hydroxynorketamine The disclosure also provides novel ketamine metabolite prodrugs. The disclosure provides methods of treating, bipolar depression, major depressive disorder, neuropathic and chronic pain, including complex regional pain disorder (CRPS) by administering a purified ketamine metabolite or a ketamine metabolite prodrug directly to patients in need of such treatment. | 10-02-2014 |
Irving William Wainer, Washington, DC US
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20140187645 | PREPARATION OF (R,R)-FENOTEROL AND (R,R)-OR (R,S)-FENOTEROL ANALOGUES AND THEIR USE IN TREATING CONGESTIVE HEART FAILURE - This disclosure concerns the discovery of (R,R)- and (R,S)-fenoterol analogues which are highly effective at binding β2-adrenergic receptors. Exemplary chemical structures for these analogues are provided. Also provided are pharmaceutical compositions including the disclosed (R,R)-fenoterol and fenoterol analogues, and methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease. | 07-03-2014 |
Jacob Wainer, Natick, MA US
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20140360420 | MULTI-COMPONENT ROBOT FOR BELOW ICE SEARCH AND RESCUE - The invention relates to remotely operated multi-component search robots for underwater search and rescue operations, and particularly suited for searches under ice. | 12-11-2014 |
Magali Audrey Valeria Wainer, Haarlem NL
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20140141275 | COATED STEEL SUBSTRATE AND METHOD FOR MAKING THE SAME - Steel substrate suitable for forming operations including a corrosion protective coating, wherein the corrosion protective coating includes a nano-layer of oxide nanoparticles and a polyamide-imide layer on the nano-layer. | 05-22-2014 |
20140150247 | POLYAMIDE-IMIDE COATED SUBSTRATE - Steel substrate suitable for forming operations which includes a coating thereon wherein the coating includes a corrosion resistant layer of polyamide-imide having a dry film thickness between 1 and 10 μm. | 06-05-2014 |
Magali Audrey Valerie Wainer, Ac Haarlem NL
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20120225309 | Method of Preparing a Polyetherimide Coating on a Metallic Substrate - A method of preparing a polyetherimide coating on a carbon steel substrate, which includes the steps of: providing an organic solvent, providing a dianhydride, providing a first diamine that is a monoaromatic diamine, providing a second diamine, placing the organic solvent, the dianhydride, the first diamine and the second diamine in a reaction vessel to form a reaction mixture, stirring the reaction mixture under inert conditions to form a polyamic acid intermediate, applying the polyamic acid intermediate on the carbon steel substrate, and curing the polyamic acid intermediate to form a polyetherimide coating. | 09-06-2012 |
Naor Wainer, Zichron Yaaqov IL
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20110012014 | SPECTRAL DETECTOR CALIBRATION - A method includes detecting radiation that traverses a material having a known spectral characteristic with a radiation sensitive detector pixel that outputs a signal indicative of the detected radiation and determining a mapping between the output signal and the spectral characteristic. The method further includes determining an energy of a photon detected by the radiation sensitive detector pixel based on a corresponding output of the radiation sensitive detector pixel and the mapping. | 01-20-2011 |
20130327947 | SINGLE OR MULTI-ENERGY VERTICAL RADIATION SENSITIVE DETECTORS - A vertical radiation sensitive detector array ( | 12-12-2013 |
Naor Wainer, Zichron Yaakov IL
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20080210877 | Double Decker Detector For Spectral Ct - A radiation detector ( | 09-04-2008 |
20100220833 | DETECTOR ARRAY FOR SPECTRAL CT - A radiation detector ( | 09-02-2010 |
20100246919 | RADIATION DETECTOR FOR COUNTING OR INTEGRATING SIGNALS - A radiation sensitive detector array ( | 09-30-2010 |
20120037809 | IMAGING MEASUREMENT SYSTEM WITH A PRINTED ORGANIC PHOTODIODE ARRAY - An imaging system includes a macro organic photodiode array with rows and columns of printed photodiodes. The array may be bendable for easy manufacture and assembly on a curved support within an imaging system. Two or more layers of photodiodes may be provided for use in a spectral CT imaging system or as slices. | 02-16-2012 |
20120153163 | IMAGING MEASUREMENT SYSTEM WITH A PRINTED PHOTODETECTOR ARRAY - Low cost large area photodetector arrays are provided. In a first embodiment, the photodetectors comprise an inorganic photoelectric conversion material formed in a single thick layer of material. In a second embodiment, the photodetectors comprise a lamination of several thin layers of an inorganic photoelectric conversion material, the combined thickness of which is large enough to absorb incoming x-rays with a high detector quantum efficiency. In a third embodiment, the photodetectors comprise a lamination of several layers of inorganic or organic photoelectric conversion material, wherein each layer has a composite scintillator coating. | 06-21-2012 |
20130058452 | CT DETECTOR INCLUDING MULTI-LAYER FLUORESCENT TAPE SCINTILLATOR WITH SWITCHABLE SPECTRAL SENSITIVITY - A scintillator element ( | 03-07-2013 |
20140070109 | IONIZING RADIATION DETECTION - A detector array ( | 03-13-2014 |
Naor Wainer, Haifa IL
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20100296625 | RADIATION DETECTOR COMPRISING A LIGHT REFLECTIVE MATERIAL - The invention relates to a light-reflecting material ( | 11-25-2010 |