Patent application number | Description | Published |
20080206712 | RESIN REINFORCED ZINC POLYCARBOXYLATE TEMPORARY CEMENT COMPOSITIONS AND RELATED KITS AND METHODS - Two-part resin-reinforced cement compositions, kits, and related methods are used for bonding a dental prosthetic appliance to a tooth. A first part includes an amine activator component and a zinc oxide reactive filler, while a second part includes a polymerization initiator (e.g., benzoyl peroxide) and a polymerizable component having a structure including at least one acrylate or methacrylate group at one end and a carboxylic acid group at another end. A temporary cement composition advantageously exhibits reduced compressive and/or bonding strength relative to permanent cement compositions, which provides sufficient strength to facilitate normal use of the teeth while the provisional appliance is in use, while also facilitating easy removal of the provisional appliance for replacement with a permanent appliance at a later time. | 08-28-2008 |
20080206715 | COLOR CHANGING DENTAL ADHESIVE COMPOSITIONS AND RELATED METHODS AND KITS - Methods, compositions, and kits for use in facilitating detection and removal of dental adhesives while minimizing and/or eliminating removal of adjacent tooth tissue. A pH sensitive color changing component (i.e., an acid/base indicator) is included within a dental adhesive composition or an activating wash composition. The adhesive composition is used to bond a dental appliance (e.g., a provisional restorative appliance or an orthodontic bracket) to a tooth. When it becomes necessary to remove the dental appliance, selective removal of the dental adhesive while minimizing and/or eliminating removal of enamel or other adjacent tooth tissue are facilitated because of the inclusion of a pH sensitive color-changing component within the dental adhesive or activating wash composition. The adhesive changes from a first color having low contrast relative to adjacent tooth tissue to a second color having greater contrast relative to adjacent tooth tissue upon application of the activating wash. | 08-28-2008 |
20080241799 | KITS AND METHODS FOR CHAIR-SIDE COATING OF ENDODONTIC CONES - Kits and methods facilitate chair-side coating of an endodontic cone for improved sealing between the hydrophilic root canal tissue, the hydrophobic elastomer substrate of the endodontic cone, and a hydrophilic sealing resin. The kit includes one or more endodontic cones (e.g., formed of gutta percha) and a micro-dose container containing an adhesive composition. The practitioner can dip the cones into the adhesive composition so as to coat the cones chair-side, just prior to use. The adhesive composition includes an adhesive resin compound comprising at least one hydrophobic region and at least one hydrophilic region. The hydrophobic region is compatible with the hydrophobic elastomer substrate of the endodontic cone, while the hydrophilic region is compatible with a hydrophilic endodontic sealing resin. | 10-02-2008 |
20080286723 | METHODS FOR CHAIR-SIDE COATING OF ENDODONTIC CONES - Kits and methods facilitate chair-side coating of an endodontic cone for improved sealing between the hydrophilic root canal tissue, the hydrophobic elastomer substrate of the endodontic cone, and a hydrophilic sealing resin. The kit includes one or more endodontic cones (e.g., formed of gutta percha) and a micro-dose container containing an adhesive composition. The practitioner can dip the cones into the adhesive composition so as to coat the cones chair-side, just prior to use. The adhesive composition includes an adhesive resin compound comprising at least one hydrophobic region and at least one hydrophilic region. The hydrophobic region is compatible with the hydrophobic elastomer substrate of the endodontic cone, while the hydrophilic region is compatible with a hydrophilic endodontic sealing resin. | 11-20-2008 |
Patent application number | Description | Published |
20100159450 | DPYD GENE VARIANTS AND USE THEREOF - Variants in DPYD gene are disclosed which can result in abnormal synthesis of DPD proteins and alteration of DPD activities. The invention provides methods for detecting the newly discovered genetic variants. The DPD genetic variants of the invention can be used as biomarkers in predicting toxicity to 5-FU and other drugs metabolized by the DPD enzyme. | 06-24-2010 |
20110311972 | DPYD GENE VARIANTS AND USE THEREOF - Variants in DPYD gene are disclosed which can result in abnormal synthesis of DPD proteins and alteration of DPD activities. The invention provides methods for detecting the newly discovered genetic variants. The DPD genetic variants of the invention can be used as biomarkers in predicting toxicity to 5-FU and other drugs metabolized by the DPD enzyme. | 12-22-2011 |
20120041274 | CANCER BIOMARKERS - Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided. | 02-16-2012 |
20120309018 | CANCER DETECTION MARKERS - Methods and compositions involving molecular markers for the detection and characterization of cancer in a patient are provided. | 12-06-2012 |
20130005610 | TOXICITY-ASSOCIATED GENES, GENETIC VARIANTS, AND USE THEREOF - Genes and genetic variants in human genomes are disclosed which are useful, inter alia, as diagnostic biomarkers. | 01-03-2013 |
20130058924 | HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION - Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular detection and classification of disease are provided. | 03-07-2013 |
20130143747 | METHODS OF DETECTING CANCER - Methods and compositions involving molecular markers for the detection and characterization of cancer in a patient are provided. | 06-06-2013 |
20130302242 | GENE SIGNATURES FOR CANCER DIAGNOSIS AND PROGNOSIS - Biomarkers and methods using the biomarkers for molecular detection and classification of disease and, particularly, molecular markers for cancer diagnosis and prognosis and methods of use thereof are provided. | 11-14-2013 |
20140113310 | CANCER DETECTION MARKERS - Methods and compositions involving molecular markers for the detection and characterization of cancer in a patient are provided. | 04-24-2014 |
20140134166 | HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION - Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular detection and classification of disease are provided. | 05-15-2014 |
20140170139 | HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION - Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular detection and classification of disease are provided. | 06-19-2014 |
20140170242 | GENE SIGNATURES FOR LUNG CANCER PROGNOSIS AND THERAPY SELECTION - The invention provides for molecular classification of disease and, particularly, molecular markers for lung cancer prognosis and therapy selection and methods and systems of use thereof. | 06-19-2014 |
20140212415 | HYPOXIA-RELATED GENE SIGNATURES FOR CANCER CLASSIFICATION - Biomarkers, particularly hypoxia-related genes, and methods using the biomarkers for molecular classification of disease are provided. | 07-31-2014 |
20140315935 | GENE SIGNATURES FOR LUNG CANCER PROGNOSIS AND THERAPY SELECTION - The invention provides for molecular classification of disease and, particularly, molecular markers for lung cancer prognosis and therapy selection and methods and systems of use thereof. | 10-23-2014 |