Thiriot
David Thiriot, Harleysville, PA US
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20100240868 | Composition and Method for a Producing Stable Amyloid Beta Oligomers of High Molecular Weight - The invention relates to a method for the preparation of a stable, soluble amyloid beta (Aβ) oligomer and composition thereof for use as an antigen for the generation of antibodies for the treatment of Alzheimer's disease and other conditions related to abnormal amyloid beta aggregation. The method which uses a pH in excess of 7.0 and high concentrations of Aβ, optionally includes the use of divalent anions or a helix-inducing solvent to form the oligomers. The stable, soluble Aβ oligomers produced by the method herein have a particle size of 10 to 100 nm in diameter, when measured by a dynamic light scattering technique, and a molecular weight of 100 to 500 kDa. | 09-23-2010 |
David S. Thiriot, Harleysville, PA US
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20140314653 | METHOD FOR PREPARATION OF ALUMINUM HYDROXYPHOSPHATE ADJUVANT - The present invention relates to methods for preparing amorphous aluminum hydroxyphosphate. An aluminum salt and a phosphate solution are co-mixed at a constant ratio in the presence of a buffer. Preferably, an excess of the phosphate solution is used to act as a buffer. Due to the presence of a buffer, the pH is maintained constant during reaction (after initial rapid equilibration) without active adjustment. The methods are particularly applicable for the large scale manufacturing of aluminum phosphate adjuvant. Aluminum phosphate is used as an adjuvant in vaccine formulations, particularly those including a protein or saccharide antigen. | 10-23-2014 |
Laurent Thiriot, Andolsheim FR
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20080277443 | Multi-functional Carry Pack Assembly for Fire Fighters - The present invention concerns a multi-functional carry pack assembly intended to equip fire fighters when fighting fires in wildland areas. The carry pack assembly of the invention comprises: a) a carry frame, preferably with at least two straps of shoulder strap type resting on the shoulders, and at least one cross-strap joined to said shoulder type straps and acting as belt, b) a first element of pouch type fixed or fixable to the carry frame, able to carry at least one water reservoir and a “hands-free” hydration system connected or connectable to said water reservoir, and c) at least one second element of pouch type fixed or fixable onto the carry frame and able to contain a protective, action or survival garment, a protective mask or at least one other accessory. | 11-13-2008 |
Remi Thiriot, Lizio FR
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20090155416 | Fermented Appetence Factors Without Animal Proteins for Animals - The invention relates to appetence factors for animal feeding. More specifically, the invention relates to an appetence factor for animal feeding, obtained by fermentation with the aid of a yeast and which comprises at least one, in the absence of protein constituents of animal origin: a humidity (H) ranging from approximately 80 to 96% by weight; a protein fraction (FP) ranging from approximately 1.5 to 10.0% by weight; fat (MG) up to approximately 10%; sugars (S) ranging from approximately 0.20 to 2.0% by weight, and ashes (C) ranging from approximately 0.3 to 8.0% by weight. | 06-18-2009 |