Tate
Aarn Tate, Christchurch NZ
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20090020580 | Backpack Systems - Backpack and counterbalance systems using load balancing pockets to be worn during active movement. The load balancing pockets of such system are arranged in the following way: a gap is created between the pockets so that the feet of the wearer are visible through the gap; the sides of the pockets do not hinder the natural swing of the arms when walking or running; this positioning is maintained whatever the size and shape of the wearer. | 01-22-2009 |
Alan Tate, Puyallup, WA US
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20140368983 | SUBSTANTIALLY TRANSPARENT HINGED SUBSTRATE APPARATUS - In various embodiments, a transparent hinged substrate apparatus integrated nto a portable computer may address common deficiencies associated with space limitations on student desktop surfaces. The transparent hinged substrate apparatus may utilize, in some embodiments, a transparent substrate that is positioned between the display side and the keypad side of a portable computer. The transparent hinged substrate apparatus may be movable into multiple positions including one position that covers the keypad side of the portable computer without touching any of the keys of the keypad. Thus, the keypad surface may now be used as a work surface using the same physical space occupied by the portable computer. | 12-18-2014 |
Alan W. Tate, Puyallup, WA US
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20150205330 | ELECTRONIC DEVICE HAVING A DETACHABLE TABLET - An electronic device may be provided that includes a base portion having an input device, a tablet having a display and a docking connector with a plurality of second electrical connectors, and a docking connector to move relative to the base portion. The docking connector may include a first docking pole to extend from the docking connector and to engage with the docking receptacle, and a plurality of first electrical connectors. | 07-23-2015 |
Allan R. Tate, Bedford, MA US
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20160062766 | UNIFORM REFERENCES - Embodiments of the present invention provide a novel and non-obvious method, system and computer program product for uniform references to artifacts in a software configuration management tool. In one embodiment, a data processing system configured to resolve artifact references can include a software configuration management tool and uniform reference resolution logic coupled to the tool. In this regard, the uniform reference logic can be programmed to resolve a path name to a referenced artifact by processing a uniform reference specifying the referenced artifact. | 03-03-2016 |
Barry J. Tate, Calgary CA
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20100206580 | Tools and Methods Useful with Wellbore Reverse Circulation - A method for reverse circulating a tool upwardly through a wellbore, the method including: providing a manipulator tool including an upper end and a lower end, conveying the manipulator tool down hole to a position adjacent a downhole tool, using the manipulator tool to manipulate the downhole tool, and reversing fluid flow through the well to create a pressure differential about at least one of the manipulator tool and the downhole tool such that the at least one of the manipulator tool and the downhole tool is lifted upwardly through the wellbore. A manipulator tool for use in a reverse circulating method is also described as are a tool catcher, a tool catching assembly and a tool catching method. | 08-19-2010 |
20130248204 | MANIPULATOR TOOL AND TOOL CATCHER USEFUL WITH WELLBORE REVERSE CIRCULATION - A method for reverse circulating a tool upwardly through a wellbore, the method including: providing a manipulator tool including an upper end and a lower end, conveying the manipulator tool down hole to a position adjacent a downhole tool, using the manipulator tool to manipulate the downhole tool, and reversing fluid flow through the well to create a pressure differential about at least one of the manipulator tool and the downhole tool such that the at least one of the manipulator tool and the downhole tool is lifted upwardly through the wellbore. A manipulator tool for use in a reverse circulating method is also described as are a tool catcher, a tool catching assembly and a tool catching method. | 09-26-2013 |
20150060046 | TOOLS AND METHODS USEFUL WITH WELLBORE REVERSE CIRCULATION - A method for reverse circulating a tool upwardly through a wellbore, the method including: providing a manipulator tool including an upper end and a lower end, conveying the manipulator tool down hole to a position adjacent a downhole tool, using the manipulator tool to manipulate a the downhole tool, and reversing fluid flow through the well to create a pressure differential about at least one of the manipulator tool and the downhole tool such that the at least one of the manipulator tool and the downhole tool is lifted upwardly through the wellbore. A manipulator tool for use in a reverse circulating method is also described as are a tool catcher, a tool catching assembly and a tool catching method. | 03-05-2015 |
Berthel Floyne Tate, Brandywine, MD US
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20150358583 | SUPPORTING PATIENT-CENTEREDNESS IN TELEHEALTH COMMUNICATIONS - A teleconferencing system includes a dominance calculator ( | 12-10-2015 |
Candice Tate, Williamsport, PA US
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20150306063 | COMPOSITION AND METHOD FOR VAGINAL THERAPY - Provided are a composition and method for vaginal therapy. The composition includes a delivery compound and a pharmaceutically active agent dispersed in the delivery compound. The pharmaceutically active agent includes a centrally acting muscle relaxant. The method for vaginal therapy includes preparing a composition including a pharmaceutically active agent dispersed in a delivery compound, and administering the composition intravaginally. The pharmaceutically active agent includes a muscle relaxant. Another method includes administering the composition extravaginally and then administering the composition intravaginally. | 10-29-2015 |
Chris Tate, Queensland AU
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20100263975 | Improvements in Movement Controls - A damping device includes a cylinder ( | 10-21-2010 |
Chris Tate, Iluka AU
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20150345556 | FLUID BEARINGS - The present invention provides improvements to a fluid bearing ( | 12-03-2015 |
Chris Tate US
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20150345556 | FLUID BEARINGS - The present invention provides improvements to a fluid bearing ( | 12-03-2015 |
Ciara Tate, Montpellier FR
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20130195817 | METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS AND VASCULOGENESIS - Disclosed herein are methods and compositions for stimulating angiogenesis, using cells descended from marrow adherent stromal cells that have been transfected with sequences encoding a Notch intracellular domain. Applications of these methods and compositions include treatment of ischemic disorders such as stroke. | 08-01-2013 |
Ciara Tate, Chicago, IL US
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20150104435 | METHODS AND COMPOSITIONS FOR PROVISION OF ANGIOGENIC FACTORS - Disclosed herein are methods and compositions for the use of marrow adherent stem cells and their descendents; e.g., bone marrow-derived neural regenerating cells; for provision of angiogenic factors to cells. In certain embodiments, provision of angiogenic factors to sites of neural degeneration stimulates growth and/or survival of host neurons. | 04-16-2015 |
Culin Tate, Potomac, MD US
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20150100598 | ASSISTED NAME CHANGE AUTOMATION SYSTEM - An assisted name change automation (ANCA) system provides analytically derived name change recommendations to women considering marital name changes. The ANCA system provides the user with a questionnaire asking a number of questions relevant to the name change decision. The results are then used to score the available choices based on a statistical analysis of a large number of prior name change decisions. A number of demographic factors may be taken into consideration, such as the subject's geographical location, age, education level, profession, whether the subject has brothers with the same last name, and so forth. The name change recommendation is then displayed to the user. A detailed report may also be presented to the user including the recommended name change, if any, along with a graphical presentation of how the user's questionnaire responses compare with the data in the historical database. | 04-09-2015 |
Danielle Tate, Potomac, MD US
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20150100598 | ASSISTED NAME CHANGE AUTOMATION SYSTEM - An assisted name change automation (ANCA) system provides analytically derived name change recommendations to women considering marital name changes. The ANCA system provides the user with a questionnaire asking a number of questions relevant to the name change decision. The results are then used to score the available choices based on a statistical analysis of a large number of prior name change decisions. A number of demographic factors may be taken into consideration, such as the subject's geographical location, age, education level, profession, whether the subject has brothers with the same last name, and so forth. The name change recommendation is then displayed to the user. A detailed report may also be presented to the user including the recommended name change, if any, along with a graphical presentation of how the user's questionnaire responses compare with the data in the historical database. | 04-09-2015 |
Gary Tate, Ada, OK US
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20140260024 | PORTABLE BUILDING - A portable building kit, construction members, and method for building a portable building are presented. The portable building includes a plurality of upright members, a plurality of footing members adapted to be connected to one or more of the plurality of upright members, a plurality of angle truss members adapted to be connected to one of the plurality of upright members, a plurality of horizontal eave brace members adapted to be connected to one or more of the plurality of upright members and one or more of the plurality of angle truss members, and a plurality of horizontal ridge brace members adapted to be connected to one or more of the plurality of angle truss members. The portable building is made by selecting a predetermined number of upright members, footing members, angle truss members, horizontal eave brace members, and horizontal ridge brace members. | 09-18-2014 |
Jason Tate, Thompsons Station, TN US
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20160067647 | FILTER WITH HIGH DUST CAPACITY - A panel filter is provided. The panel filter can have extended life or higher dust holding capacity by one or more of the following provisions of (a) placing the dimpled pattern (compressed region) on the downstream side and outlet face of the media, (b) using the dimpled media in combination with adhesive spacers and embossments, (c) selection of a media that is depth loading rather than surface loading, (d) operating the pleater/embossing assembly in a manner so as to maintain integrity of the dimples and/or other features as described herein. | 03-10-2016 |
J.d. Tate, Freeport, TX US
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20160109413 | METHODS AND SYSTEMS FOR MEASURING CORROSION IN-SITU - Systems and methods for measuring corrosion rate of an equipment material are provided. A system may comprise a corrosion probe body for insertion within an interior of the equipment through which corrodant fluid flows. At least one sensor on the corrosion probe body includes an ultrasonic source configured to provide an ultrasonic signal into the probe body material, and a receiver configured to receive reflections of the ultrasonic signal from the probe body material and generate electrical response signals indicative of the travel time of the ultrasonic signal. A heat exchanger may be placed in fluid communication with the probe body to deliver heated or cooled fluids to the probe body. A processor is configured to process the electrical response signals and produce corresponding corrosion data. | 04-21-2016 |
Jennifer A. Tate, Hopkinton, MA US
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20140219926 | Biodegradable Iron Oxide Nanoparticle Gel for Tumor Bed Therapy - A biodegradable iron oxide nanoparticle gel for hyperthermia treatment of cancer includes a polysaccharide-based carrier matrix and starch-coated iron oxide nanoparticles. The gel has sufficient deformability to integrate into a diffuse tumor site, adheres to tissue and has sufficient mechanical properties to remain in place during hyperthermia treatment. The gel releases iron oxide nanoparticles for uptake by cancerous cells at the tumor margin. | 08-07-2014 |
Kevin Tate, Roswell, GA US
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20150047124 | Bed Sheet with Compartment for Feet - A bed sheet placed on a mattress for bedding includes a region of fabric defining a compartment for surrounding a user's feet at one end of the mattress. | 02-19-2015 |
Leon J. Tate, Cranberry Township, PA US
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20150335821 | RADIOPHARMACEUTICAL ADMINISTRATION METHODS, FLUID DELIVERY SYSTEMS AND COMPONENTS THEREOF - A fluid path set for a fluid delivery system includes a tube coil that is designed to optimally position one or more volumes of a pharmaceutical within an ionization chamber to optimally measure and prepare a pharmaceutical dose for administration to a patient. The tube coil may be maintained in a desired dimensional geometry by means of a core structure around which the tube coil is positioned. Novel developments in radiopharmaceutical administration methods and systems include, but are not limited to, the configuration and layout of a fluid path set for use in a fluid delivery system, arrangements for piercing and drawing fluid from a pharmaceutical container (such as a vial), arrangements for optimizing the positioning of a tube coil within an ionization chamber, a handling system for transporting vial shields that maintain an operator's hand and fingers at a safe distance from a pharmaceutical vial, a method for calibrating a radiopharmaceutical delivery system in which the difference between the expected and measured activities of two radioisotopes are used to calculate an estimated error in the measured activity of a third radioisotope and a vial access system that ensures an optimal draw of fluid from a radiopharmaceutical container. | 11-26-2015 |
Mark W. Tate, Ithaca, NY US
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20140190730 | CONDUCTING POLYMER NANOFIBERS, METHODS OF MAKING AND USING SAME, AND USES THEREOF - Provided are conducting polymer nanofibers, methods of making conducting polymer nanofibers, and uses thereof. The conducting polymer nanofibers can be formed by, for example, electrospinning, force spinning, and centrifugal spinning using a spinning dope. The conducting polymer nanofibers can be used in devices, such as a radiation detecting device. | 07-10-2014 |
Martha Lillian Tate, Sandy Springs, GA US
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20140188194 | Method and Apparatus to Increase Tactile Senstivity and Proprioception in Humans - The article is a support to which an electrode pair, a positive and corresponding negative electrode, is attached. Leads are electrically attached to each of the positive and negative electrodes, wherein each lead has an insulated coating. A controller is electrically attached to the leads for delivering monophasic or biphasic electrical stimulation at a single frequency. A power supply is electrically connected to the controller, and may be attached to the support. The article may be a sock, a glove, a harness or an insole. | 07-03-2014 |
Michael Tate, Mouans Sartoux FR
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20140204942 | METHODS OF ESTABLISHING VIRTUAL CIRCUITS AND OF PROVIDING A VIRTUAL PRIVATE NETWORK SERVICE THROUGH A SHARED NETWORK, AND PROVIDER EDGE DEVICE FOR SUCH NETWORK - A virtual private network (VPN) service is provided through a shared network infrastructure comprising interconnected provider edge (PE) devices having customer edge (CE) interfaces. Some of the CE interfaces are allocated to a VPN supporting virtual LANs. A correspondence between a CE interface and a virtual LAN is learnt on the basis of tagged frames received at this CE interface and including an identifier of this virtual LAN. The learning process permits the detection of pairs of CE interfaces which correspond to a common virtual LAN. Upon such detection, a virtual circuit is established in the shared network infrastructure between the PE devices having these CE interfaces, and subsequently used for forwarding frames including the identifier of the common virtual VLAN. | 07-24-2014 |
20140204951 | METHODS OF ESTABLISHING VIRTUAL CIRCUITS AND OF PROVIDING A VIRTUAL PRIVATE NETWORK SERVICE THROUGH A SHARED NETWORK, AND PROVIDER EDGE DEVICE FOR SUCH NETWORK - A virtual private network (VPN) service is provided through a shared network infrastructure comprising interconnected provider edge (PE) devices having customer edge (CE) interfaces. Some of the CE interfaces are allocated to a VPN supporting virtual LANs. A correspondence between a CE interface and a virtual LAN is learnt on the basis of tagged frames received at this CE interface and including an identifier of this virtual LAN. The learning process permits the detection of pairs of CE interfaces which correspond to a common virtual LAN. Upon such detection, a virtual circuit is established in the shared network infrastructure between the PE devices having these CE interfaces, and subsequently used for forwarding frames including the identifier of the common virtual VLAN. | 07-24-2014 |
Michael Lewis Tate, Rangiora NZ
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20110184652 | METHODS OF GENERATING GENETIC PREDICTORS EMPLOYING DNA MARKERS AND QUANTITATIVE TRAIT DATA - A genetic trait predictor is generated by blending individual molecular estimates with estimates of at least one genetic value derived from quantitative trait measure. The individual molecular estimates may include molecular trait estimates or molecular trait variance. The individual molecular estimates may be determined by applying individual deoxyribonucleic acid (DNA) markers, DNA marker panels, specific parameter estimates and specific parameter variance thereof, and a genotype of a test sample. Quantitative trait measure may include estimated breeding data, raw trait data, and breed composition data. The genetic predictor is accurate and stable under a wide range of conditions and relatively immune to errors in parameter estimation. | 07-28-2011 |
Quinn Tate, North Salt Lake, UT US
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20160123998 | Devices, Systems, and Methods for Measuring Blood Loss - Devices, systems, and methods for measuring the blood loss of a subject during a medical procedure. Blood and other fluids are received within a container, and a blood measurement device determines the hemoglobin concentration of the fluid within the container. The blood measurement device can also calculate the estimated blood loss of the subject based upon the determined hemoglobin concentration and the volume of the fluid within the container and the patient's hemoglobin. | 05-05-2016 |
Rodney James Tate, Queensland AU
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20120112149 | APPARATUS AND METHOD RELATING TO FENCING - An apparatus and method for fencing in which a mobile apparatus has a plurality of posts held with wires passing through respective aligned holes and means to take a post at a time to an into the ground driver with the wire or wires still extending through apertures in the post. | 05-10-2012 |
Rodney James Tate, Marochydore Qld AU
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20120110930 | POST INSTALLATION - A method of securing an elongate member in the ground which includes the steps of embedding the member within a matching size and shaped hole in the ground then ensnaring the member with a ground anchor that passes substantially through the member intersecting the member. The invention also applies to a member with a ground anchor positioned therein and also having a tightening nut. | 05-10-2012 |
Ronald C. Tate, Battle Ground, IN US
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20150377927 | Cover Removal Switch Having Lever-Arm - A meter cover removal detection arrangement includes a switch element, a pivoting lever arm, a meter cover and a plunger. The switch element has first and second positions, and conducts electricity between first and second contacts in only one of the first position and the second position. The pivoting lever arm has two arm positions, and is operably coupled to cause the switch element to be in the second position when the lever arm is in a second arm position. The lever arm engages a spring that biases the level arm toward the second arm position. The meter cover has an inward extending cam. The plunger has first and second plunger positions, and is operably coupled to hold the pivoting lever arm in the first arm position when the plunger is in the first plunger position. The cam engages the plunger to hold the plunger in the first plunger position when the meter cover is installed on a meter base. The cam is disengaged from the plunger when the meter cover is removed. | 12-31-2015 |
20160084884 | Service Switch With High Current Arc Protection - An arrangement for use in a utility meter includes an actuator element configured for linear movement. The actuator is operably coupled to receiving moving power from a prime mover, and includes a plurality of receptacles for corresponding contact arms of a switch within an electricity meter. Each receptacle is defined by an outer bar, an inner bar, and opposing stiffening elements. The outer bar is configured to engage a first surface of a contact arm element when the switch is in a first position, and the inner bar configured to engage a second surface of the contact arm element when the switch is in a second position. | 03-24-2016 |
Shaun Tate, Grand Blanc, MI US
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20150071579 | ROLLING BEARING HAVING RINGS WITH STEPPED SURFACES OPPOSITE TO THE RACEWAYS - A rolling bearing is provided that includes an outer ring having a first portion which includes a first raceway and a second portion that includes a second raceway that has a larger diameter than the first raceway. An outer diameter of the first portion of the outer ring is less than an outer diameter of the second portion of the outer ring. The rolling bearing includes an inner ring having a first portion that includes a first raceway and a second portion that includes a second raceway that has a larger diameter than the first raceway. An inner diameter of the first portion of the inner ring is less than an inner diameter of the second portion of the inner ring. | 03-12-2015 |
20150110430 | BEARING ASSEMBLY INCLUDING TAPERED ROLLERS AND SPHERICAL ROLLING ELEMENTS - A bearing assembly is provided. The assembly includes a plurality of tapered rollers and a plurality of spherical rolling elements. A first inner ring defines a first inner raceway on which the plurality of tapered rollers run, and a second inner ring defines a second inner raceway on which the plurality of spherical rolling elements run. A unitary outer ring includes a first portion defining a first outer raceway on which the plurality of tapered rollers run, and a second portion defining a second outer raceway on which the plurality of spherical rolling elements run. | 04-23-2015 |
Stephen A. Tate, Barrie CA
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20130124102 | SYSTEMS AND METHODS FOR PROCESSING FRAGMENT ION SPECTRA TO DETERMINE MECHANISM OF FRAGMENTATION AND STRUCTURE OF MOLECULE - Correlated fragment ions of a molecule are grouped using mass spectrometry with ramps in collision energy (CE). A known molecule is fragmented and analyzed at a plurality of different collision energies using a mass spectrometer. A plurality of variables for a plurality of fragment ions are produced. Principal component analysis is performed on the plurality of variables. A number of principal components produced by the principal component analysis is selected. A subset principal component space is created having the number of principal components. A variable in the subset principal component space is selected. A spatial angle is defined around a vector extending from an origin to the variable. A set of one or more variables within the spatial angle of the vector is selected. The set is assigned to a group, if the set includes a minimum number of variables. | 05-16-2013 |
20130153761 | Systems and Methods for Using Variable Mass Selection Window Widths in Tandem Mass Spectrometry - Systems and methods are used to analyze a sample using variable mass selection window widths. A tandem mass spectrometer is instructed to perform at least two fragmentation scans of a sample with different mass selection window widths using a processor. The tandem mass spectrometer includes a mass analyzer that allows variable mass selection window widths. The selection of the different mass selection window widths can be based on one or more properties of sample compounds. The properties may include a sample compound molecular weight distribution that is calculated from a molecular weight distribution of expected compounds or is determined from a list of molecular weights for one or more known compounds. The tandem mass spectrometer can also be instructed to perform an analysis of the sample before instructing the tandem mass spectrometer to perform the at least two fragmentation scans of the sample. | 06-20-2013 |
20130206979 | Data Independent Acquisition of Product Ion Spectra and Reference Spectra Library Matching - Systems and methods are used to store an electronic record of all product ion spectra of all detectable compounds of a sample. A plurality of product ion scans are performed on a tandem mass spectrometer one or more times in a single sample analysis across a mass range using a plurality of mass selection windows. All sample product ion spectra of all detectable compounds for each mass selection window are produced. All sample product ion spectra for each mass selection window are received from the tandem mass spectrometer using a processor. All sample product ion spectra for each mass selection window are stored as an electronic record of all detectable compounds of the sample using the processor. The electronic record is used to characterize compounds known at the time the electronic record is stored or to characterize compounds that became known after the electronic record was stored. | 08-15-2013 |
20130240723 | Systems and Methods for Rapidly Screening Samples by Mass Spectrometry - Systems and methods are used to rapidly screening samples. A fast sample introduction device that is non-chromatographic is instructed to supply each sample of a plurality samples to a tandem mass spectrometer using a processor. The fast sample introduction device can include a flow injection analysis device, an ion mobility analysis device, or a rapid sample cleanup device. The tandem mass spectrometer is instructed to perform fragmentation scans at two or more mass selection windows across a mass range of each sample of the plurality of samples using the processor. The two or more mass selection windows across the mass range can have fixed or variable window widths. The tandem mass spectrometer can be instructed to obtain a mass spectrum of the mass range before instructing the tandem mass spectrometer to perform the fragmentation scans. | 09-19-2013 |
20130289894 | Method for Triggering Dependent Spectra for Data Acquisition - Methods and systems are provided for triggering an information dependent mass spectrometry scan in real time. A mass spectrometry scan of a separating sample mixture is performed by a mass spectrometer at each time interval of a time period. The mass spectrometer receives the separating sample mixture from a separation device. It is determined at a certain time interval that a received mass spectrometry scan at the time interval and one or more preceding received mass spectrometry scans include two or more time-varying ion signals that represent two or more fragment ion transitions of a known compound. If a characteristic of the two or more time-varying ion signals meets a selection criterion, the mass spectrometer is instructed to perform a dependent mass spectrometry scan of the separating sample mixture for a precursor ion of the known compound at the time interval. | 10-31-2013 |
20140332681 | Use of Windowed Mass Spectrometry Data for Retention Time Determination or Confirmation - A scan of a separating sample is received by a mass spectrometer at each interval of a plurality of intervals. The spectrometer performs at each interval one or more mass spectrometry scans. The scans have one or more sequential mass window widths in order to span an entire mass range at each interval and produce a collection of spectra for the entire mass range for the plurality of intervals. One or more peaks at one or more different intervals in the collection of spectra are identified for a fragment ion. A mass spectrum of the entire mass range is retrieved for each interval of each peak. Values for one or more ion characteristics of a mass-to-charge ratio peak in the mass spectrum corresponding to each peak are compared to one or more known values for the fragment ion. Each peak is scored based on the comparison. | 11-13-2014 |
20150097113 | Modulation of Instrument Resolution Dependant upon the Complexity of a Previous Scan - Systems and methods are used to analyze a sample using variable detection scan resolutions. A tandem mass spectrometer is instructed to perform at least two scans of a sample with different detection scan resolutions using a processor. The tandem mass spectrometer includes a mass analyzer that allows variable detection scan resolutions. The selection of the different detection scan resolutions can be based on one or more properties of sample compounds. The properties may include a sample compound molecular weight distribution that is calculated from a molecular weight distribution of expected compounds or is determined from a list of molecular weights for one or more known compounds. The tandem mass spectrometer can also be instructed to perform an analysis of the sample before instructing the tandem mass spectrometer to perform the at least two scans of the sample. | 04-09-2015 |
20150129757 | Systems and Methods for Using Variable Mass Selection Window Widths in Tandem Mass Spectrometry - Systems and methods are used to analyze a sample using variable mass selection window widths. A tandem mass spectrometer is instructed to perform at least two fragmentation scans of a sample with different mass selection window widths using a processor. The tandem mass spectrometer includes a mass analyzer that allows variable mass selection window widths. The selection of the different mass selection window widths can be based on one or more properties of sample compounds. The properties may include a sample compound molecular weight distribution that is calculated from a molecular weight distribution of expected compounds or is determined from a list of molecular weights for one or more known compounds. The tandem mass spectrometer can also be instructed to perform an analysis of the sample before instructing the tandem mass spectrometer to perform the at least two fragmentation scans of the sample. | 05-14-2015 |
20150129758 | Systems and Methods for Sequencing Peptides by Mass Spectrometry - The number of atoms present in an ion of a molecule is identified using a mixture of different forms of the molecule. A mass spectrometer analyzes a mixture of at least two forms of the molecule using one or more ion scans producing a mass spectrum. The first form of the molecule includes a first combination of isotopes of one or more elements. The second form of the molecule includes a second combination of isotopes of the one or more elements. A first peak and a second peak that differ in mass by a multiple of a mass difference between the first combination of isotopes and the second combination of isotopes are located in the mass spectrum. The number of atoms of the one or more elements present in an ion of the molecule is identified from a mass difference between the first peak and the second peak. | 05-14-2015 |
20150136968 | Systems and Methods for Using Interleaving Window Widths in Tandem Mass Spectrometry - Systems and methods are provided for analyzing a sample using overlapping measured mass selection window widths. A mass range of a sample is divided into two or more target mass selection window widths using a processor. The two or more target widths can have the same width or variable widths. A tandem mass spectrometer is instructed to perform two or more fragmentation scans across the mass range using the processor. Each fragmentation scan of the two or more fragmentation scans includes a measured mass selection window width. The two or more measured widths of the two or more fragmentation scans can have the same width or variable widths. At least two of the two or more measured mass selection window widths overlap. The overlap in measured mass selection window widths corresponds to at least one target mass selection window width. | 05-21-2015 |
20150144778 | Data Independent Acquisition of Product Ion Spectra and Reference Spectra Library Matching - Systems and methods are used to store an electronic record of all product ion spectra of all detectable compounds of a sample. A plurality of product ion scans are performed on a tandem mass spectrometer one or more times in a single sample analysis across a mass range using a plurality of mass selection windows. All sample product ion spectra of all detectable compounds for each mass selection window are produced. All sample product ion spectra for each mass selection window are received from the tandem mass spectrometer using a processor. All sample product ion spectra for each mass selection window are stored as an electronic record of all detectable compounds of the sample using the processor. The electronic record is used to characterize compounds known at the time the electronic record is stored or to characterize compounds that became known after the electronic record was stored. | 05-28-2015 |
20150248998 | Systems and Methods for Identifying Compounds from MS/MS Data without Precursor Ion Information - Systems and methods are provided for identifying a precursor ion without using any a priori precursor ion information. In one method, a sample is analyzed using a tandem mass spectrometer, producing at least one measured product ion spectrum from a precursor mass-to-charge ratio range. The at least one measured product ion spectrum are received. A subset of measured product ions is selected from the at least one measured product ion spectrum. A list of candidate compounds is created by searching a dictionary of potential compounds that includes one or more predicted product ions for each of the potential compounds using the subset of measured product ions. A candidate compound on the list is selected as the identified compound. In another method, the measured product ions are assumed to correspond to shortened forms of the peptide and a protein database is searched for shortened forms of the peptide. | 09-03-2015 |
20150248999 | Systems and Methods for Acquiring Data for Mass Spectrometry Images - Systems and methods are provided for maximizing the data acquired from a sample in a mass spectrometry imaging experiment. An ion source device is instructed to produce and transmit to a tandem mass spectrometer a plurality of ions for each location of two or more locations of a sample. A mass range is divided into two or more mass window widths. For each location of the two or more locations, the tandem mass spectrometer is instructed to fragment the plurality of ions received for each location using each mass window width of the two or more mass window widths and to analyze resulting product ions. A product ion spectrum is produced for each mass window width, and a plurality of product ion spectra are produced for each location of the two or more locations. | 09-03-2015 |
20150279644 | Data Independent Acquisition of Product Ion Spectra and Reference Spectra Library Matching - Systems and methods are disclosed for identifying detectable compounds of a sample. Sample product ion spectra are received for each mass selection window of precursor mass selection windows for each time step. The received sample product ion spectra are searched for the presence of known compounds of interest with known product ion spectra by retrieving a known product ion spectrum from a library, retrieving the sample product ion spectra corresponding to the precursor mass selection window expected to contain a precursor ion corresponding to the known product ion spectrum, generating product ion traces in time for the retrieved sample product ion spectra, calculating a score for the product ion traces and the retrieved sample product ion spectra that represents how well the retrieved sample product ion spectra and the known product ion spectrum match, and confirming the identity of a precursor ion using the score. | 10-01-2015 |
20150287579 | Data Independent Acquisition of Product Ion Spectra and Reference Spectra Library Matching - Systems and methods are disclosed for quantitating detectable compounds of a sample. Sample product ion spectra are received for each mass selection window for each time step. The received sample product ion spectra are searched for the presence of known compounds of interest with known product ion spectra by retrieving the known product ion spectra from a library, retrieving the sample product ion spectra corresponding to the precursor mass selection window expected to contain a precursor ion corresponding to the known product ion spectra, generating product ion traces in time for the sample product ion spectra for the known product ion spectra, calculating a score for the product ion traces and product ion spectra that represents how well known product ions and sample product ions match, and calculating a quantitative value for the known compound from the product ion traces when the score exceeds a threshold value. | 10-08-2015 |
20160042930 | Systems and Methods for Using Interleaving Window Widths in Tandem Mass Spectrometry - Systems and methods are provided for analyzing a sample using overlapping measured mass selection window widths. A mass range of a sample is divided into two or more target mass selection window widths using a processor. The two or more target widths can have the same width or variable widths. A tandem mass spectrometer is instructed to perform two or more fragmentation scans across the mass range using the processor. Each fragmentation scan of the two or more fragmentation scans includes a measured mass selection window width. The two or more measured widths of the two or more fragmentation scans can have the same width or variable widths. At least two of the two or more measured mass selection window widths overlap. The overlap in measured mass selection window widths corresponds to at least one target mass selection window width. | 02-11-2016 |
20160042933 | Removal of Ions from Survey Scans Using Variable Window Band-Pass Filtering to Improve Intrascan Dynamic Range - Systems and methods are used to band-pass filter ions from a mass range. A full spectrum is received for a full scan of a mass range using a tandem mass spectrometer. A mass selection window of the full spectrum is selected and a set of tuning parameter values is selected. The tandem mass spectrometer is instructed to perform a scan of the mass selection window using the set of tuning parameter values. A spectrum is received for the scan from the tandem mass spectrometer. A band-pass filtered spectrum is created for the mass range that includes values from the spectrum for the mass selection window of the mass range. Systems and methods are also used to band-pass filter ions from two or more mass selection windows across the mass range and to filter out ions from a mass selection window between two band-pass mass selection windows. | 02-11-2016 |
20160079047 | Systems and Methods for Using Variable Mass Selection Window Widths in Tandem Mass Spectrometry - Systems and methods are used to analyze a sample using variable mass selection window widths. A tandem mass spectrometer is instructed to perform at least two fragmentation scans of a sample with different mass selection window widths using a processor. The tandem mass spectrometer includes a mass analyzer that allows variable mass selection window widths. The selection of the different mass selection window widths can be based on one or more properties of sample compounds. The properties may include a sample compound molecular weight distribution that is calculated from a molecular weight distribution of expected compounds or is determined from a list of molecular weights for one or more known compounds. The tandem mass spectrometer can also be instructed to perform an analysis of the sample before instructing the tandem mass spectrometer to perform the at least two fragmentation scans of the sample. | 03-17-2016 |
20160079048 | Systems and Methods for Rapidly Screening Samples by Mass Spectrometry - Systems and methods are used to rapidly screening samples. A fast sample introduction device that is non-chromatographic is instructed to supply each sample of a plurality samples to a tandem mass spectrometer using a processor. The fast sample introduction device can include a flow injection analysis device, an ion mobility analysis device, or a rapid sample cleanup device. The tandem mass spectrometer is instructed to perform fragmentation scans at two or more mass selection windows across a mass range of each sample of the plurality of samples using the processor. The two or more mass selection windows across the mass range can have fixed or variable window widths. The tandem mass spectrometer can be instructed to obtain a mass spectrum of the mass range before instructing the tandem mass spectrometer to perform the fragmentation scans. | 03-17-2016 |
20160086783 | Improved Data Quality after Demultiplexing of Overlapped Acquisition Windows - Systems and methods are provided for identifying missing product ions after demultiplexing product ion spectra produced by overlapping precursor ion transmission windows in sequential windowed acquisition tandem mass spectrometry. Overlapping sequential windowed acquisition is performed on a sample. A first precursor mass window and the corresponding first product ion spectrum are selected from a plurality of overlapping stepped precursor mass windows and their corresponding product ion spectra. A product ion spectrum is demultiplexed for each overlapped portion of the first precursor mass window producing two or more demultiplexed first product ion spectra for the first precursor mass window. The two or more demultiplexed first product ion spectra are added together producing a reconstructed summed demultiplexed first product ion spectrum. Missing product ions are identified in the summed demultiplexed first product ion spectrum by comparing the summed demultiplexed first product ion spectrum and the first product ion spectrum. | 03-24-2016 |
20160093482 | Modulation of Instrument Resolution Dependant upon the Complexity of a Previous Scan - Systems and methods are used to analyze a sample using variable detection scan resolutions. A tandem mass spectrometer is instructed to perform at least two scans of a sample with different detection scan resolutions using a processor. The tandem mass spectrometer includes a mass analyzer that allows variable detection scan resolutions. The selection of the different detection scan resolutions can be based on one or more properties of sample compounds. The properties may include a sample compound molecular weight distribution that is calculated from a molecular weight distribution of expected compounds or is determined from a list of molecular weights for one or more known compounds. The tandem mass spectrometer can also be instructed to perform an analysis of the sample before instructing the tandem mass spectrometer to perform the at least two scans of the sample. | 03-31-2016 |
20160099136 | Systems and Methods for Acquiring Data for Mass Spectrometry Images - Systems and methods are provided for maximizing the data acquired from a sample in a mass spectrometry imaging experiment. An ion source device is instructed to produce and transmit to a tandem mass spectrometer a plurality of ions for each location of two or more locations of a sample. A mass range is divided into two or more mass window widths. For each location of the two or more locations, the tandem mass spectrometer is instructed to fragment the plurality of ions received for each location using each mass window width of the two or more mass window widths and to analyze resulting product ions. A product ion spectrum is produced for each mass window width, and a plurality of product ion spectra are produced for each location of the two or more locations. | 04-07-2016 |
Stephen A. Tate, North York CA
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20140095084 | Use of Variable XIC Widths of TOF-MSMS Data for the Determination of Background Interference in SRM Assays - Systems and methods identify a product ion that does not include an interference. A full product ion spectrum for a mass range of an analyte in a sample is received from a tandem mass spectrometer. A first set of one or more peak parameters is calculated for a product ion in the full product ion spectrum using a first XIC window width. A second set of one or more peak parameters is calculated for the product ion using a second XIC window width. The product ion is identified as not including an interference, if the first set of one or more peak parameters and the second set of one or more peak parameters are substantially the same. The product ion is further confirmed or determined to be from the analyte and not from a matrix of the sample by correlating the product to a precursor ion of the analyte. | 04-03-2014 |
20140117224 | Removal of Ions from Survey Scans Using Variable Window Band-Pass Filtering to Improve Intrascan Dynamic Range - Systems and methods are used to band-pass filter ions from a mass range. A full spectrum is received for a full scan of a mass range using a tandem mass spectrometer. A mass selection window of the full spectrum is selected and a set of tuning parameter values is selected. The tandem mass spectrometer is instructed to perform a scan of the mass selection window using the set of tuning parameter values. A spectrum is received for the scan from the tandem mass spectrometer. A band-pass filtered spectrum is created for the mass range that includes values from the spectrum for the mass selection window of the mass range. Systems and methods are also used to band-pass filter ions from two or more mass selection windows across the mass range and to filter out ions from a mass selection window between two band-pass mass selection windows. | 05-01-2014 |
Stephen Alexander Tate, Barrie CA
Patent application number | Description | Published |
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20140353490 | MASS SPECTROMETRY SYSTEMS AND METHODS FOR IMPROVED MULTIPLE REACTION MONITORING - The present teachings are directed to methods and apparatuses for mass spectrometry that include configuring mass spectrometry apparatus to perform a plurality of separate assays on ions fragmented from a given analyte, where each such analysis by the spectrometry apparatus is targeted at a different respective associated mass-to-charge ratio and provides a quantitative measure of the number of fragments thereof. | 12-04-2014 |
20150034815 | METHOD FOR MASS SPECTROMETRY - A method is provided for mass spectrometry. The method includes generating precursor ions from a sample; transmitting the precursor ions into a collision cell; generating product ions in the collision cell; detecting the precursor and product ions; applying modulation to one or more of the precursor ion intensity and the product ion intensity; and identifying precursor ion and product ion relationships by analyzing intensity profiles defined by the modulation. | 02-05-2015 |
Trent S. Tate, Austin, TX US
Patent application number | Description | Published |
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20150128475 | FISHING ROD - A fishing rod that includes an elongated, tapered rod blank at least a portion of which is quadrilateral in cross section, the quadrilateral portion of the rod blank diminishing in cross-sectional area toward a tip end of the rod blank, the quadrilateral portion of the rod blank comprising a sandwich-structured composite of a core disposed between facings, the core less dense than the facings, the quadrilateral portion of rod blank less stiff in a casting direction than transverse to the casting direction; fishing line guides mounted at intervals along the length of the rod blank; a reel seat mounted at the base end of the rod blank; and a handle mounted at the base end of the rod blank adjacent to the reel seat. | 05-14-2015 |
Warren Perry Tate, Dunedin NZ
Patent application number | Description | Published |
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20090215051 | Novel Assay - The invention relates to a translational recoding reporter construct comprising: a first fluorescent protein coding sequence; a second fluorescent protein coding sequence encoding a fluorescent protein different from the first fluorescent protein; and a linker sequence interposed between the first and second fluorescent protein coding sequence; wherein the a first fluorescent protein coding sequence and the second fluorescent protein coding sequence are out-of-frame with respect to each other but are co-expressed as a single fusion polypetpdie upon recoding. The invention also relates to methods of use of the construct in screening modulators of recoding. | 08-27-2009 |
Yonathan Tate, Herzlia Pituach IL
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20160094245 | LDPC DECODER WITH EFFICIENT CIRCULAR SHIFTERS - A decoder includes variable-node circuitry, check-node circuitry and a Message Passing (MP) module, which includes multiple configurable partial cyclic shifters that each supports only a partial subset of shift values out of a full range of shift values 0 . . . L−1. The variable-node circuitry and check-node circuitry are configured to exchange messages with one another in accordance with a parity check matrix that represents a respective Quasi-Cyclic (QC)-Low Density Parity Check (LDPC) Error Correcting Code (ECC) and that includes L-by-L sub-matrices, and to process the exchanged messages to decode a given code word that was encoded using the QC-LDPC ECC. The MP module is configured to schedule the variable-node circuitry and check-node circuitry that are interconnected in accordance with a respective sub-matrix to exchange L messages simultaneously by assigning a given partial cyclic shifter to shift the L messages cyclically a number of positions that depends on a structure of the respective sub-matrix. | 03-31-2016 |