Patent application number | Description | Published |
20080225292 | TARGET SUBSTANCE DETECTING ELEMENT, TARGET SUBSTANCE DETECTION APPARATUS AND TARGET SUBSTANCE DETECTION METHOD - Magnetic particles with a metal coat holding target substance captors are made to react with a target substance contained in a specimen in a solution where the magnetic particles are dispersed in a liquid medium. Subsequently, the dispersion of the magnetic particles is applied to a surface having a periodic structure that is adapted to generate plasmon resonance and a change in the plasmon resonance attributable to the concentration of the target substance held on the magnetic particles fixed magnetically to the surface is optically detected to determine the concentration of the target substance in the specimen. | 09-18-2008 |
20080241964 | MATERIAL FOR IMPROVING SENSITIVITY OF MAGNETIC SENSOR AND METHOD THEREOF - The present invention relates to a capture agent member being used in a magnetic sensor to detect the presence or concentration of a target substance in a test solution by detecting the presence or number of the magnetic marker, wherein the capture agent member contains a capture agent for capturing the target substance and a labeling agent serving as a nucleus for the magnetic marker to agglutinate, and wherein the capture agent is labeled with the labeling agent. The present invention relates to a material which improves detection sensitivity of a biosensor using a magnetic sensor while maintaining reactivity and dispersibility. In particular, according to the present invention, there can be provided a material which enables realization of high sensitivity by using a simple magnetic biosensor such as a semiconductor Hall element and a magnetoresistance effect element. | 10-02-2008 |
20080309323 | METHOD FOR BIOCHEMICAL ANALYSIS - It is intended to provide a supersensitive, quick and accurate method for biochemical analysis. The method includes: adding magnetic fine particles into a solution containing a target substance, whereby a first substance for detection immobilized on the magnetic fine particle is bound to the target substance, while aggregating the magnetic fine particles so as to form an aggregate in the solution; next binding the target substance bound with the magnetic fine particle constituting the aggregate to a second substance for detection on a magnetic sensor layer so as to immobilize the aggregate onto the surface of the magnetic sensor layer; and measuring a magnetic stray field of this aggregate using a magnetic sensor. | 12-18-2008 |
20090000360 | Method for Detecting Target Substance and Target-Substance Detection Kit - The present invention provides a method for detecting a target substance by detecting the presence or concentration of a target substance in a sample solution by bringing the sample solution into contact with a detecting element including a detecting part and a non-detecting part and detecting the presence or number of a magnetic label (magnetic marker) present in the vicinity of the surface of the detecting part and provides a target-substance detection kit. The surface potential ψ | 01-01-2009 |
20090021250 | TARGET SUBSTANCE DETECTION KIT AND TARGET SUBSTANCE DETECTION METHOD - The present invention allows a target substance to be detected easily without applying an external magnetic field to a magnetic marker. The present invention provides a target substance detection kit including: a target substance detection board which contains a magnetic sensor and a first target substance capture molecule; and a magnetic marker which contains a magnetic structure and a second target substance capture molecule, wherein the first target substance capture molecule exists on a surface of the target substance detection board, and the magnetic structure generates a magnetic stray field under polarized light. | 01-22-2009 |
20090042317 | SUBSTANCE IMMOBILIZING APPARATUS, SUBSTANCE DETECTING APPARATUS AND SUBSTANCE IMMOBILIZING METHOD - The efficiency of the specific binding of a target substance to an immobilization region is increased. As a first step, target substance | 02-12-2009 |
20100047928 | TARGET SUBSTANCE DETECTION ELEMENT, TARGET SUBSTANCE DETECTION METHOD, AND METHOD FOR PRODUCING TARGET SUBSTANCE DETECTION ELEMENT - It is intended to provide a target substance detection element wherein a target substance capturing body for capturing target substances is immobilized with good orientation in a desired region on the surface of the target substance detection element, a method for producing the target substance detection element, and a detection method using the target substance detection element. The present invention provides a target substance detection element for detecting the presence or absence or concentration of a target substance in a sample, characterized in that: the target substance detection element includes at least a detection substrate including plural layers and a target substance capturing body immobilized on the surface of the detection substrate; the target substance capturing body has at least a first peptide region specifically recognizing a first layer of the plural layers constituting the detection substrate and binding to the first layer and a second peptide region specifically recognizing a second layer different from the first layer of the plural layers and binding to the second layer; and the first layer and the second layer are adjacent to each other. | 02-25-2010 |
20100188079 | DETECTION APPARATUS AND DETECTION METHOD FOR MAGNETIC SUBSTANCE - A magneto-impedance element used for detection of a magnetic substance has a structure that can trap magnetic substances locally in a predetermined band-like region on the lateral surface thereof or a structure that can detect the presence of a magnetic substance based on a change of the impedance in response to application of magnetic fields. The magneto-impedance element is used to provide a detection apparatus and a detection method that can easily detect a magnetic substance with high precision. | 07-29-2010 |
20100213935 | MAGNETIC DETECTION ELEMENT AND DETECTION METHOD - A magnetic detection element, comprises a core composed of a soft magnetic material, a detecting coil for detecting a magnetic field applied to the core, and an exciting coil for applying an alternating magnetic field to the core, wherein the surface of the core is divided into a first region and a second region in the longitudinal direction of the detecting coil, the first region and the second region being different in affinity for a detection object substance. | 08-26-2010 |
20110117675 | SUBSTANCE IMMOBILIZING APPARATUS, SUBSTANCE DETECTING APPARATUS AND SUBSTANCE IMMOBILIZING METHOD - The efficiency of the specific binding of a target substance to an immobilization region is increased. As a first step, target substance | 05-19-2011 |
20110117676 | MAGNETIC SENSOR, PRODUCTION METHOD OF THE SAME, AND TARGET SUBSTANCE DETECTING APPARATUS AND BIOSENSOR KIT USING THE SAME - The present invention provides a magnetic sensor which detects a target substance indirectly by making a labeling substance larger than the target substance bond with the target substance contained in a sample in a detection area, and detecting the labeling substance, comprising a capture area which is relatively easy to capture the target substance, and a non-capture area which is relatively hard to capture the target substance, on a surface of a member which is comprised in a detection area, wherein the capture area is surrounded by the non-capture area. Thereby, the sensor enables to detect comparatively accurately the number and concentration of substances which cannot be directly detected, and enables to be used for detection of various target substances. | 05-19-2011 |
20110136264 | METHOD FOR DETECTING TARGET SUBSTANCE AND TARGET-SUBSTANCE DETECTION KIT - The present invention provides a method for detecting a target substance by detecting the presence or concentration of a target substance in a sample solution by bringing the sample solution into contact with a detecting element including a detecting part and a non-detecting part and detecting the presence or number of a magnetic label (magnetic marker) present in the vicinity of the surface of the detecting part and provides a target-substance detection kit. The surface potential ψ | 06-09-2011 |