Patent application number | Description | Published |
20090270380 | 3,4,5-Substituted Piperidines as Renin Inhibitors - The application relates to novel substituted piperidines of the general formula (II) in which R | 10-29-2009 |
20100029628 | 2,4,5-Substituted Piperidines as Renin Inhibitors - SP-P2140 ATE-132—Abstract Novel substituted piperidines of the general formula (I) and (II) with the substituent definitions as explained in detail in the description are described. The compounds are suitable in particular as renin inhibitors and are highly potent. | 02-04-2010 |
20100331322 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS - The present invention relates to compounds of the general formula (I) and the salts thereof, preferably the pharmaceutically acceptable salts thereof; in which R has the meaning explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors. | 12-30-2010 |
20110009399 | ORGANIC COMPOUNDS - The application relates to trisubstituted piperidines of the general formula (I) and their salts, preferably their pharmaceutically acceptable salts, in which R | 01-13-2011 |
20110053924 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS - The present invention relates to compounds of the general formula (I) and the salts thereof, preferably the pharmaceutically acceptable salts thereof; in which R has the meaning explained in the description, a process for their preparation and the use of these compounds as medicines, especially as renin inhibitors. | 03-03-2011 |
20110212950 | 4,4-DISUBSTITUTED PIPERIDINES - The application relates to 4,4-disubstituted piperidines of the general formula (I) and their salts, preferably their pharmaceutically acceptable salts, in which R | 09-01-2011 |
20110301196 | TRYPSIN-LIKE SERINE PROTEASE INHIBITORS, AND THEIR PREPARATION AND USE - The invention provides compounds that are effective as inhibitors of human plasmin and plasma kallikrein, and that are useful for the prevention of blood loss and as components of fibrin adhesives. The invention further provides methods of making and using the compounds. | 12-08-2011 |
20120115859 | 3,4,5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS - The application relates to novel substituted piperidines of the general formula (II) in which R | 05-10-2012 |
20120252743 | TRYPSIN-LIKE SERINE PROTEASE INHIBITORS, THEIR PREPARATION AND USE AS SELECTIVE INHIBITORS OF THE CLOTTING FACTORS IIA AND XA - The invention provides methods of making and using compounds of the formula: | 10-04-2012 |
20140073573 | TRYPSIN-LIKE SERINE PROTEASE INHIBITORS, AND THEIR PREPARATION AND USE - The invention provides compounds that are effective as inhibitors of human plasmin and plasma kallikrein, and that are useful for the prevention of blood loss and as components of fibrin adhesives. The invention further provides methods of making and using the compounds. | 03-13-2014 |