Patent application number | Description | Published |
20080300268 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 12-04-2008 |
20090137588 | HETEROARYL COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 05-28-2009 |
20090163497 | Compounds Useful as Antagonists of CCR2 -
The present invention provides compounds of general formula (I) or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R | 06-25-2009 |
20090181966 | PGD2 receptor antagonists for the treatment of inflammatory diseases - Disclosed herein are compounds represented by Structural Formula (I) and (I-A): | 07-16-2009 |
20090197884 | Compounds Useful as Antagonists of CCR2 - The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions. | 08-06-2009 |
20090275556 | Aryl sulfonamides useful as inhibitors of chemokine receptor activity - The present invention provides compounds of general formula I: | 11-05-2009 |
20090281081 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREFOR - Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: | 11-12-2009 |
20090306085 | HCV PROTEASE INHIBITORS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 12-10-2009 |
20100016289 | Compounds Useful as Antagonists of CCR2 - The present invention provides compounds of general formula I: (I) or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R | 01-21-2010 |
20100016296 | HETEROARYL COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 01-21-2010 |
20100069294 | HCV PROTEASE INHIBITORS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 03-18-2010 |
20100197723 | BICYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME - Disclosed herein are compounds that may be modulators of 5-HT receptors, and methods of making and using same. | 08-05-2010 |
20100249174 | CCR1 ANTAGONISTS AND METHODS OF USE THEREFOR - The invention provides compounds having the formula: | 09-30-2010 |
20100324035 | Carboxamide Compounds and Their Use - Chemokine receptor antagonists, in particular, compounds of Formula (I-A) that act as antagonists of the chemokine CCR2 receptor, including pharmaceutical compositions and uses thereof to treat or prevent diseases associated with monocyte accumulation, lymphocyte accumulation or leukocyte accumulation are described herein. | 12-23-2010 |
20100331298 | Carboxamide Compounds and Their Use - Chemokine receptor antagonists, in particular, compounds of Formula (I) that act as antagonists of the chemokine CCR2 receptor, including pharmaceutical compositions and uses thereof to treat or prevent diseases associated with monocyte accumulation, lymphocyte accumulation or leukocyte accumulation are described herein. | 12-30-2010 |
20110046362 | METHODS OF MAKING NUCLEOSIDE TETRAPHOSPHATE - The invention provides compounds and methods for making adenosine-ribofuranoside tetraphosphate compounds. The compounds are contemplated to have activity at the P2Y receptor and may be used in the treatment of medical disorders such as cystic fibrosis and upper respiratory disorders. | 02-24-2011 |
20110117073 | Protein Kinase Conjugates and Inhibitors - The invention relates to protein conjugates that contain a protein kinase containg a cysteine residue in the ATP binding site and an inhibitor that is covalently and irreversibly bonded to said cysteine residue, such that the activity of the protein kinase is irreversibly inhibited. The invention also relates to compounds that irreversibly inhibit protein kinases. | 05-19-2011 |
20110224432 | HETEROARYL COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 09-15-2011 |
20110230494 | HETEROARYL COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 09-22-2011 |
20110230516 | CCR1 Antagonists and Methods of Use Therefor - The invention provides compounds having the formula: | 09-22-2011 |
20110237601 | Substituted piperazinyl-pyrrolidine compounds useful as chemokine receptor antagonists - The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided: | 09-29-2011 |
20110281873 | Pyrimidine Compounds and Methods of Making and Using Same - Disclosed herein are pyrimidinyl compounds that are contemplated to be modulators of cystic fibrosis transmembrane regulators (CFTR), and methods of making and using same. Also provided are pharmaceutical compositions and methods of treating disorders associated with cystic fibrosis transmembrane regulators, such as airway inflammation, cystic fibrosis, and the like. | 11-17-2011 |
20120046311 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF - Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: | 02-23-2012 |
20120088793 | Bicyclic Compounds and Methods of Making and Using Same - Disclosed herein are compounds that may be modulators of 5-HT receptors, and methods of making and using same. | 04-12-2012 |
20120208818 | COMPOUNDS USEFUL AS ANTAGONISTS OF CCR2 - The present invention provides compounds of general formula I: | 08-16-2012 |
20120214807 | COMPOUNDS USEFUL AS ANTAGONISTS OF CCR2 - The present invention provides compounds of general formula I: | 08-23-2012 |
20120238593 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 09-20-2012 |
20130065892 | HETEROARYL COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 03-14-2013 |
20130123270 | SUBSTITUTED PIPERAZINYL-PYRROLIDINE COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS - The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided: | 05-16-2013 |
20130131105 | HCV PROTEASE INHIBITORS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 05-23-2013 |
20130217688 | HETEROARYL COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 08-22-2013 |
20130289063 | CCR1 ANTAGONISTS AND METHODS OF USE THEREFOR - The invention provides compounds having the formula: | 10-31-2013 |
20140073661 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 03-13-2014 |
20140303165 | HETEROARYL COMPOUNDS AND USES THEREOF - The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same. | 10-09-2014 |
20140364420 | SUBSTITUTED PIPERAZINYL-PYRROLIDINE COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS - The present invention relates to compounds useful as Chemokine Receptor antagonists. Compounds of general formula I are provided: | 12-11-2014 |
20140371207 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF - Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: | 12-18-2014 |