Patent application number | Description | Published |
20090075313 | Split protein fragments, split protein systems, methods of making split protein systems, and methods of using split protein systems - Split protein herpes simplex virus type 1 thymidine kinase [HSV1-TK or TK] TK fragments, split protein TK systems, methods of imaging protein-protein interactions, methods of cellular localization of proteins, methods of evaluating protein translocation and trafficking, and the like, are provided. In addition, the present disclosure includes compositions used in and methods relating to non-invasive imaging (e.g., positron emission tomography (PET) imaging) in vivo and in vitro. | 03-19-2009 |
20100008862 | Fluorescent magnetic nanoprobes, methods of making, and methods of use - Embodiments of the present disclosure provide for nanoprobes, methods of imaging, methods of imaging a target, methods of making nanoprobes, and the like. | 01-14-2010 |
20110059014 | COMPOUNDS AND METHODS OF MAKING COMPOUNDS - Embodiments of the present disclosure provide for compounds and methods of making compounds such as those shown in FIGS. | 03-10-2011 |
20110059439 | COMPOSITION AND METHOD FOR IMAGING STEM CELLS - An expression vector, comprising a first reporter nucleic acid sequence operably linked to a first expression control sequence comprising a promoter; and a second reporter nucleic acid sequence operably linked to a second expression control sequence that comprises a response element that is activated or inactivated as one or more of the cells differentiate or dedifferentiate. Methods and kits for imaging and monitoring stem cells comprising the expression vector are also provided. | 03-10-2011 |
20110230760 | Raman imaging devices and methods of molecular imaging - In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to Raman imaging devices (e.g., Raman endoscope probes), methods of using Raman agents and Raman imaging devices to image or detect a signal, and the like. | 09-22-2011 |
20140046179 | Dual-isotope positron emitting tomography for disease evaluation - Simultaneous dual-isotope positron emission tomography (PET) is used to improve disease evaluation. Two distinct molecular probes are simultaneously provided to the imaging target. One of the probes is labeled with a radionuclide that emits positrons to provide double coincidence events in PET. The other probe is labeled with a radionuclide that emits positrons+prompt gammas to provide triple coincidence events in PET. One of the probes is a metabolic probe, and the other probe is a selective probe that includes a ligand or antibody that is biologically responsive to receptor/antigen status. A PET system is employed that can provide simultaneous double coincidence and triple coincidence PET images. The resulting images provide simultaneous metabolic imaging and receptor/antigen imaging. Applications include disease evaluation, such as cancer staging (e.g., for breast cancer, prostate cancer, etc.). | 02-13-2014 |
20140316255 | Raman Imaging Devices and Methods of Molecular Imaging - In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to Raman imaging devices (e.g., Raman endoscope probes) or systems, methods of using Raman agents, Raman imaging devices, and/or systems to image or detect a signal, and the like. | 10-23-2014 |
20150118157 | Compounds and Methods of Making Compounds - Embodiments of the present disclosure provide for compounds and methods of making compounds such as those shown in | 04-30-2015 |